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<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQD5</accession>
    <name>A4RQD5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_85999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415713.1">
        <property type="nucleotide sequence ID" value="XM_001415676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQD5"/>
    <dbReference type="GeneID" id="4999705"/>
    <dbReference type="Gramene" id="ABO94005">
        <property type="protein sequence ID" value="ABO94005"/>
        <property type="gene ID" value="OSTLU_85999"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_85999"/>
    <dbReference type="eggNOG" id="ENOG502RXRT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048953_1_1_1"/>
    <dbReference type="OMA" id="HWSPPQP"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF49">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="407" mass="45611" checksum="D6ACF1F3DA6B70B6" modified="2007-05-15" version="1">MLHHAIVIVAAAGRGGRAPRPGRGGRSNRSDAPDWAKPPAEGRQKRASTSKPPPNGGGGRGERTNDGARAASSKATTSKGEPSRERAVRASDDLRAVSANASTKNFDDGGRGTTTLFDDGGRGTTLEECLRYEREGHTCIRGAVDAMEMIPMVKALSGEIMSRRMEAYRHRVSVLCPQVDARELRDVEDAKRALKKHSQEDVGFLQTFNLHREQTSAAREYIMSKRFAKIAAELMGCERARIYQSCIFVKEPGMAETNWHSDLNMVPLDTNDFVTLWIPLRSLEEDDAALHFANRSHRDFSLPYWRTLEGMEDLEGRYEIDTYDELDLGDLTAHHGWCLHWSPPQPEDCVPRYALSVCYFADGARRLDTDQLRRVPHDEDAWSYDSWLKDIKPGAVAKHPELPIVWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQI7</accession>
    <name>A4RQI7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_6786</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415395.1">
        <property type="nucleotide sequence ID" value="XM_001415358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQI7"/>
    <dbReference type="STRING" id="436017.A4RQI7"/>
    <dbReference type="GeneID" id="4999570"/>
    <dbReference type="Gramene" id="ABO93687">
        <property type="protein sequence ID" value="ABO93687"/>
        <property type="gene ID" value="OSTLU_6786"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6786"/>
    <dbReference type="eggNOG" id="KOG0852">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_21_1_1"/>
    <dbReference type="OMA" id="HYAFGDV"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF171">
        <property type="entry name" value="PEROXIREDOXIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO93687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="192" mass="21459" checksum="32EC54A180A7779C" modified="2007-05-15" version="1" fragment="single">EVKIGQPAPQFDSPACVDGDLGRVKLSDYLGKYCVVFFYPLDFTFVCPTEITAFNDRADEFEALNTKVIAVSTDSEYSHLAWTMMERERGGLGAMRIPIVSDRTKEISAKYGVLFEDRGIALRGLFIIDDEGIVQQITMNNLPVGRSVDETLRLVRAFQYTAEHGEVCPAGWTPGAPTMIDDPEKSKTYFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQK6</accession>
    <name>A4RQK6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415406.1">
        <property type="nucleotide sequence ID" value="XM_001415369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQK6"/>
    <dbReference type="GeneID" id="4999953"/>
    <dbReference type="Gramene" id="ABO93698">
        <property type="protein sequence ID" value="ABO93698"/>
        <property type="gene ID" value="OSTLU_13610"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13610"/>
    <dbReference type="HOGENOM" id="CLU_1373895_0_0_1"/>
    <dbReference type="OMA" id="NTREAGH"/>
    <dbReference type="OrthoDB" id="10377308at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="Lamin A/C globular tail domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LTD" evidence="1">
        <location>
            <begin position="14"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="208" mass="22888" checksum="6D64C01335F0F3DA" modified="2007-05-15" version="1">MCVVVAEATSIPAEPREVTRYGAAQITEISYEQLDAADATEGETAGSGDWIEIYNPSETDKVDLTGWAFTDRSARAIEKNPEVAVGHWFELPELELAPKSFAVLARDEMAFRTAYRDRDNALDALVRGSFKFGLTAKGETVRLLDASNETVYELTYDDKSPWPDTSEGGHSLELIDVRLDPNDPFSWISSYEEGGTPGEINSIAVSWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR09</accession>
    <name>A4RR09_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">OBG-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_3188</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415822.1">
        <property type="nucleotide sequence ID" value="XM_001415785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR09"/>
    <dbReference type="STRING" id="436017.A4RR09"/>
    <dbReference type="GeneID" id="4999637"/>
    <dbReference type="Gramene" id="ABO94114">
        <property type="protein sequence ID" value="ABO94114"/>
        <property type="gene ID" value="OSTLU_3188"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3188"/>
    <dbReference type="eggNOG" id="KOG1490">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011784_6_0_1"/>
    <dbReference type="OMA" id="RFEDYLW"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NOG1 N-terminal helical" evidence="3">
        <location>
            <begin position="3"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleolar GTP-binding protein 1 Rossman-fold" evidence="2">
        <location>
            <begin position="230"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32141" checksum="7B4276328187F40A" modified="2007-05-15" version="1" fragment="single">GAFGRLPNVSPAEQLIASAVKRAGRVTPTRGLKDAARERNKSAKQLDALTTGVCKPLKEYVKGFPPPERLHPFERALLELTLSDKKYRTTLAAVDSMRKGMLGIGKGYASQVTKTTALKEAEEMREKGFAEMEAYYRKYARCVDDLKSIAKLLRKLPVAELETPTVALVGAPNVGKSSLVRVLSSGLPEVCNYPFTTKGIKMGHFFVDDERHVVTDTPGLINRSEADRNKIEMLTIATLEHLPTCVIFVTDLTGLSGTSIDDQLQLREELYKQFAERRPWIDVFSKSALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR96</accession>
    <name>A4RR96_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_39993</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415532.1">
        <property type="nucleotide sequence ID" value="XM_001415495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR96"/>
    <dbReference type="STRING" id="436017.A4RR96"/>
    <dbReference type="GeneID" id="4999679"/>
    <dbReference type="Gramene" id="ABO93824">
        <property type="protein sequence ID" value="ABO93824"/>
        <property type="gene ID" value="OSTLU_39993"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39993"/>
    <dbReference type="eggNOG" id="KOG1870">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001060_8_2_1"/>
    <dbReference type="OMA" id="GSCQLIW"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="33"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO93824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="688" mass="76846" checksum="63DA4D194DD1A119" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRY6</accession>
    <name>A4RRY6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415648.1">
        <property type="nucleotide sequence ID" value="XM_001415611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRY6"/>
    <dbReference type="GeneID" id="4999893"/>
    <dbReference type="Gramene" id="ABO93940">
        <property type="protein sequence ID" value="ABO93940"/>
        <property type="gene ID" value="OSTLU_29182"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29182"/>
    <dbReference type="HOGENOM" id="CLU_797846_0_0_1"/>
    <dbReference type="OrthoDB" id="568470at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="295"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="39779" checksum="49064FB87A7C222D" modified="2007-05-15" version="1">MRARVDDILRAQPTSQSIPAEVVAYELKRLILELDENVHDSARSSTWPSVRTFFVDSLQLIESSEPARRVAEALRDLEASFLITSQKQQWLDGEREDWLETVRLVARVVDRPLMTFGLLRVIGSLLNDLAMSLKEGSFVPAFTRPRTAVDATRKSLWHARVEAILISGIATDERDARVLEERYFSDVLRLRAPEASEQPVLLNATRFVAPMPREETRVPAERERELRLAQSYNFSTDVLIRRQETRRRCAPRRLMISDEDEDDPYSAVGGDAEELERLRGEVARLQIEREQEVLCTICYSNKRDTVVCPCLHLMYCSACIARLRDQGGSEARCPHCRCAMTGLLQIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRZ5</accession>
    <name>A4RRZ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_29190</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415651.1">
        <property type="nucleotide sequence ID" value="XM_001415614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRZ5"/>
    <dbReference type="STRING" id="436017.A4RRZ5"/>
    <dbReference type="GeneID" id="4999882"/>
    <dbReference type="Gramene" id="ABO93943">
        <property type="protein sequence ID" value="ABO93943"/>
        <property type="gene ID" value="OSTLU_29190"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29190"/>
    <dbReference type="eggNOG" id="KOG1654">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119276_0_1_1"/>
    <dbReference type="OMA" id="AVYQEHK"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000010">
        <property type="entry name" value="Autophagy-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO93943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="15009" checksum="DB27ED62CF661AFA" modified="2007-05-15" version="1">MSAKFAFKQEHPFDKRASESARIRGKYNDRVPVIVERAEKSDAPTLDKKKYLVPADLTVGQFVYVIRKRIKLSAEKAIFIFVNNVLPPTAALMSAVYEEHKDEDGFLYVTYSGENTFGGERASDEDDEASVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSI6</accession>
    <name>A4RSI6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">procollagen-proline 4-dioxygenase</fullName>
            <ecNumber evidence="4">1.14.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_6831</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the P4HA family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416487.1">
        <property type="nucleotide sequence ID" value="XM_001416450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSI6"/>
    <dbReference type="STRING" id="436017.A4RSI6"/>
    <dbReference type="GeneID" id="5000266"/>
    <dbReference type="Gramene" id="ABO94780">
        <property type="protein sequence ID" value="ABO94780"/>
        <property type="gene ID" value="OSTLU_6831"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6831"/>
    <dbReference type="eggNOG" id="KOG1591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058132_5_0_1"/>
    <dbReference type="OMA" id="DRWLEVI"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000002">
        <property type="entry name" value="Prolyl 4-hydroxylase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="16">
        <location>
            <begin position="77"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="17">
        <location>
            <begin position="221"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO94780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="255" mass="28007" checksum="134392F86C161C6A" modified="2007-05-15" version="1" fragment="single">PRAFVYEGFLTDEECDHILALSKGHLHKSGVVDAKTGGSTTSDIRTSTGTFISRAHDPTITAIEERIELWSQIPVDHGEALQVLRYENGQEYKAHFDYFFHKGGKRNNRIATVLLYLSDVEEGGETVFPNTDVPTDRDRSQYSECGNGGKSVKARKGDALLFWSMKPGGELDPGSSHAGCPVIKGVKWTATKWMHVNAIGKHGDDVHKIFYEGGPQATESCKDTDDACRGWAESGECDKNPGFMLKSCAMSCRAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT12</accession>
    <name>A4RT12_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fip1 motif containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Fip1</name>
        <name evidence="8" type="ORF">OSTLU_119510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416398.1">
        <property type="nucleotide sequence ID" value="XM_001416361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT12"/>
    <dbReference type="STRING" id="436017.A4RT12"/>
    <dbReference type="GeneID" id="5000525"/>
    <dbReference type="Gramene" id="ABO94691">
        <property type="protein sequence ID" value="ABO94691"/>
        <property type="gene ID" value="OSTLU_119510"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119510"/>
    <dbReference type="eggNOG" id="KOG1049">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_850981_0_0_1"/>
    <dbReference type="OrthoDB" id="1917198at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044976">
        <property type="entry name" value="FIPS5/FIPS3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36884">
        <property type="entry name" value="FIP1[III]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36884:SF4">
        <property type="entry name" value="FIP1[III]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="7">
        <location>
            <begin position="127"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="266"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="327" mass="37276" checksum="F4E7B6C862E70159" modified="2007-05-15" version="1">MTGFSREKGLNEEKLFGEIFHSGETGSGAERTRSTPESLEERRGTEFVKHDDRKIPQPPPGKPRTGRESVSSRLPDGRWNTYNGQMPNARYNELQQRILPGGEGGARFIPPDEYKEFLQLGHGGVFDLDLDNIDVAPWRRRGAELNSYFNYGFTERSWRLYIKEIRRARMELHLRNSIEIGFTENNSTVDTDLPPEVRRALGGWEYEGQSRSTSLPPVGSSHEVLGVKNTEYLLQPSENFHNESQVNTQQLYEGTRPAQVKMNSQQQSMEAKLAGGEMTLEELREEAQNIQSEYRALVASSTLSSAKNYELQSKMLEIKKRIAQYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT66</accession>
    <name>A4RT66_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29977</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the dispatched family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416127.1">
        <property type="nucleotide sequence ID" value="XM_001416090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT66"/>
    <dbReference type="STRING" id="436017.A4RT66"/>
    <dbReference type="GeneID" id="5000081"/>
    <dbReference type="Gramene" id="ABO94419">
        <property type="protein sequence ID" value="ABO94419"/>
        <property type="gene ID" value="OSTLU_29977"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29977"/>
    <dbReference type="eggNOG" id="KOG3664">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_297790_0_0_1"/>
    <dbReference type="OMA" id="HIGHAYA"/>
    <dbReference type="OrthoDB" id="497871at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007224">
        <property type="term" value="P:smoothened signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052081">
        <property type="entry name" value="Dispatched_Hh_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003392">
        <property type="entry name" value="PTHD_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45951:SF3">
        <property type="entry name" value="PROTEIN DISPATCHED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45951">
        <property type="entry name" value="PROTEIN DISPATCHED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02460">
        <property type="entry name" value="Patched"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="831"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="856"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="888"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="929"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="963"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="382"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1011" mass="109954" checksum="887A36A4EC55CB3D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTB8</accession>
    <name>A4RTB8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleolar protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_14147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416339.1">
        <property type="nucleotide sequence ID" value="XM_001416302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTB8"/>
    <dbReference type="SMR" id="A4RTB8"/>
    <dbReference type="STRING" id="436017.A4RTB8"/>
    <dbReference type="GeneID" id="5000313"/>
    <dbReference type="Gramene" id="ABO94632">
        <property type="protein sequence ID" value="ABO94632"/>
        <property type="gene ID" value="OSTLU_14147"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14147"/>
    <dbReference type="eggNOG" id="KOG2188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_405679_0_0_1"/>
    <dbReference type="OMA" id="MIGKNRH"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="620"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="620"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="659"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="74131" checksum="345B6563A8A72109" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTC8</accession>
    <name>A4RTC8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Septum formation protein MAF-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Maf</name>
        <name evidence="2" type="ORF">OSTLU_119388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416332.1">
        <property type="nucleotide sequence ID" value="XM_001416295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTC8"/>
    <dbReference type="GeneID" id="5000160"/>
    <dbReference type="Gramene" id="ABO94625">
        <property type="protein sequence ID" value="ABO94625"/>
        <property type="gene ID" value="OSTLU_119388"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119388"/>
    <dbReference type="eggNOG" id="KOG1509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040416_4_1_1"/>
    <dbReference type="OMA" id="EEVCGFC"/>
    <dbReference type="OrthoDB" id="10267058at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.950.10:FF:000008">
        <property type="entry name" value="Maf-like protein, expressed"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF4">
        <property type="entry name" value="7-METHYL-GTP PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="236" mass="25742" checksum="5EFB209B1DC64F6C" modified="2007-05-15" version="1">MRATTTWTRRCAWIVRTRACGRNEAIARAMNAKTVAERLKETSTAVILGSGSATRRAILSGMNIEYVIEKPDIDEKAIRFDDPEVLVRALASAKATAVREKLAERGEGARRLLITCDQVVVHRGIIREKPTSASEAREFIRGYGLDPPSTVGSTMVTDLSSGKSASAVDVNTVVFDEIPDDVVNAIVDEGECMFCAGGLMVEHPLLQPYLKRIEGSMDGVMGLDAQTVERLLNEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTE5</accession>
    <name>A4RTE5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416088.1">
        <property type="nucleotide sequence ID" value="XM_001416051.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RTE5"/>
    <dbReference type="GeneID" id="5000547"/>
    <dbReference type="Gramene" id="ABO94380">
        <property type="protein sequence ID" value="ABO94380"/>
        <property type="gene ID" value="OSTLU_24019"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24019"/>
    <dbReference type="eggNOG" id="ENOG502R2CI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_230620_0_0_1"/>
    <dbReference type="OMA" id="FHPQRRI"/>
    <dbReference type="OrthoDB" id="10434166at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044782">
        <property type="term" value="P:cilium organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030791">
        <property type="entry name" value="Rotatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31691">
        <property type="entry name" value="ROTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31691:SF1">
        <property type="entry name" value="ROTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="2253" mass="241957" checksum="9CBBB12A72D6D8AF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU96</accession>
    <name>A4RU96_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416920.1">
        <property type="nucleotide sequence ID" value="XM_001416883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU96"/>
    <dbReference type="GeneID" id="5000862"/>
    <dbReference type="Gramene" id="ABO95213">
        <property type="protein sequence ID" value="ABO95213"/>
        <property type="gene ID" value="OSTLU_30543"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30543"/>
    <dbReference type="HOGENOM" id="CLU_2077041_0_0_1"/>
    <dbReference type="OMA" id="GEEPWWI"/>
    <dbReference type="OrthoDB" id="10519731at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="118" mass="12597" checksum="79F365750B7E0345" modified="2007-05-15" version="1">MASVARARAPPRAIATTARVPRRGARAVRRATTSKGGTKTSSSSSKGSKGRGGSTKNLINYVPKPDAPEPWWPVDERTGKPPGWFQFVVFAGSQLFIGVVMQPAALVYQSLFDPIVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="118" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV19</accession>
    <name>A4RV19_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="14">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_14777</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="14"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417061.1">
        <property type="nucleotide sequence ID" value="XM_001417024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV19"/>
    <dbReference type="STRING" id="436017.A4RV19"/>
    <dbReference type="GeneID" id="5000604"/>
    <dbReference type="Gramene" id="ABO95354">
        <property type="protein sequence ID" value="ABO95354"/>
        <property type="gene ID" value="OSTLU_14777"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14777"/>
    <dbReference type="eggNOG" id="KOG0202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_3_2_1"/>
    <dbReference type="OMA" id="PLWNNMM"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000003">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000014">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000065">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005782">
        <property type="entry name" value="P-type_ATPase_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01116">
        <property type="entry name" value="ATPase-IIA1_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="312"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="776"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="809"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="849"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="938"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="24"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO95354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1025" mass="111413" checksum="C977D697A75B3711" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVR4</accession>
    <name>A4RVR4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417458.1">
        <property type="nucleotide sequence ID" value="XM_001417421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVR4"/>
    <dbReference type="GeneID" id="5001206"/>
    <dbReference type="Gramene" id="ABO95751">
        <property type="protein sequence ID" value="ABO95751"/>
        <property type="gene ID" value="OSTLU_31070"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31070"/>
    <dbReference type="HOGENOM" id="CLU_2709245_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="8472" checksum="C2DD18AE9CF5F9CF" modified="2007-05-15" version="1">MRVEKPIATVARATQYLPQVVESKWRRNRAFQTRNAGLPTVHHIKFCRRTEIIKYNTSKADAKATHLSANHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVW5</accession>
    <name>A4RVW5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417220.1">
        <property type="nucleotide sequence ID" value="XM_001417183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVW5"/>
    <dbReference type="GeneID" id="5001323"/>
    <dbReference type="Gramene" id="ABO95513">
        <property type="protein sequence ID" value="ABO95513"/>
        <property type="gene ID" value="OSTLU_31123"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31123"/>
    <dbReference type="HOGENOM" id="CLU_1013343_0_0_1"/>
    <dbReference type="OMA" id="RKRANCA"/>
    <dbReference type="OrthoDB" id="10330354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="275" mass="30400" checksum="25040B87B8603FCE" modified="2007-05-15" version="1">MPAHREFALTEYFVSVDARKRANCATDAVDGFVKINHGLCVEIPLFARVGLALTNAFYWVLAWKLLRSTGMFDDSQCARDLCRSHAFHVLLVFGIASASTAYHFYQLGLDREISRASRSACDCFKFRGFTLPGTGTTSKKVKASPLKVTSLRQLSDERVGFDRLRSDSARDLSASAACSPSPTKPSVTTMSLYNYPGELVRWLCAMDIGCAIIYGVFCATCFGAEKILSAGRLPTVFLVTAMICQRAEKYWAYVVLHSIWHALSAALMLDFLLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW38</accession>
    <name>A4RW38_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417256.1">
        <property type="nucleotide sequence ID" value="XM_001417219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW38"/>
    <dbReference type="STRING" id="436017.A4RW38"/>
    <dbReference type="GeneID" id="5001161"/>
    <dbReference type="Gramene" id="ABO95549">
        <property type="protein sequence ID" value="ABO95549"/>
        <property type="gene ID" value="OSTLU_92615"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92615"/>
    <dbReference type="HOGENOM" id="CLU_867118_0_0_1"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="321" mass="34942" checksum="AFD2ADEBDD99F87A" modified="2007-05-15" version="1">MEVDSDDDTWRLNLNDAWTSDSEGEVRAKPSTSAAKFARAELDAVNVDIDAAPATTTAPRGDVNASKYALTLPNELGVLTVAQIHKCELGTVVWNAALILCDWLRANAGTLRGRTILEVGAGCGACGFYAAACGADCIIADCGPQTMLNLEKTLACYENLVAKRPGGGSFAGNVKIRRHLWEEDFEILEARRLGEIPGRVRHWSNVGVFENEGAGFAAPMAPTDVFDIVIGSDLLYFSSQEESLLAALRLRLKPGRVCYIVQTLRTNNAEVFARFVLAARRYFVVDIVSASLPNANVFLRAKETPHALLDDPYRLLTLRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW96</accession>
    <name>A4RW96_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutathione transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_15097</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily. Mu family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417544.1">
        <property type="nucleotide sequence ID" value="XM_001417507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW96"/>
    <dbReference type="STRING" id="436017.A4RW96"/>
    <dbReference type="GeneID" id="5001284"/>
    <dbReference type="Gramene" id="ABO95837">
        <property type="protein sequence ID" value="ABO95837"/>
        <property type="gene ID" value="OSTLU_15097"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15097"/>
    <dbReference type="eggNOG" id="KOG1695">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039475_2_1_1"/>
    <dbReference type="OMA" id="LCYTDFE"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF222">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="6">
        <location>
            <begin position="2"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="7">
        <location>
            <begin position="88"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="231" mass="25751" checksum="7F1201AAFA953E74" modified="2007-05-15" version="1">MPKIELGYWPIRGLGAPARMLCEYAGADYADVNYADAGSWFAGKKPELASGNALINLPYVECDGQVVTHSSVVLEFLGQVTGVDAFASEDHRWANAQALAEIYDLRNALMGVVYPFNGKTTTKEAFEKNCDDHMNATVGKFYAKFETLLKQRGMEFLIRDAPSSADFHLFEMLDQHEIIANRRGMKSPLETFPELKRYHANFKALPQLEKYFASAAYALPMNSIGGGAWIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWF4</accession>
    <name>A4RWF4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1,4-alpha-glucan branching enzyme</fullName>
            <ecNumber evidence="4">2.4.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_31320</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Amyloplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417321.1">
        <property type="nucleotide sequence ID" value="XM_001417284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWF4"/>
    <dbReference type="STRING" id="436017.A4RWF4"/>
    <dbReference type="CAZy" id="CBM48">
        <property type="family name" value="Carbohydrate-Binding Module Family 48"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="GeneID" id="5001520"/>
    <dbReference type="Gramene" id="ABO95614">
        <property type="protein sequence ID" value="ABO95614"/>
        <property type="gene ID" value="OSTLU_31320"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31320"/>
    <dbReference type="eggNOG" id="KOG0470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011131_2_2_1"/>
    <dbReference type="OMA" id="YEMHLGS"/>
    <dbReference type="OrthoDB" id="196493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009501">
        <property type="term" value="C:amyloplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11321">
        <property type="entry name" value="AmyAc_bac_euk_BE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02854">
        <property type="entry name" value="E_set_GBE_euk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000001">
        <property type="entry name" value="1,4-alpha-glucan branching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000250">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651:SF2">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME, CHLOROPLASTIC_AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0035">Amyloplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="233"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="726"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="751" mass="84652" checksum="13B679ED461D6E7B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWN5</accession>
    <name>A4RWN5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_6612</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417610.1">
        <property type="nucleotide sequence ID" value="XM_001417573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWN5"/>
    <dbReference type="STRING" id="436017.A4RWN5"/>
    <dbReference type="GeneID" id="5001270"/>
    <dbReference type="Gramene" id="ABO95903">
        <property type="protein sequence ID" value="ABO95903"/>
        <property type="gene ID" value="OSTLU_6612"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6612"/>
    <dbReference type="eggNOG" id="KOG0724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1163687_0_0_1"/>
    <dbReference type="OMA" id="LTSREMW"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000023">
        <property type="entry name" value="protein REVEILLE 6 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF146">
        <property type="entry name" value="PROTEIN REVEILLE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24904">
        <property type="entry name" value="RVE6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="11"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="239" mass="27061" checksum="A3E95A79B290EF48" modified="2007-05-15" version="1" fragment="single">KKPRKPYTQTRARVSWTPKEHQRFLRALELYSRDWKRIEEYVGSKDVVQIRSHAQKHFLKLMKSGQGDQMPPPRHKKSNHADGERAVNYVPGMSQAMRLRLQVEPDGSLPVAPKRAPGVPPPLQNSTNTPDFATVYGFLADLFKVNEARTEPEHALRLSHTTPLENMTAIDRETALLLIRNLRNNMCSKQMWQQQSDLLEDGCSTFLDAQDAERLRPKTFGKVSDASPDDNSSGDGSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWP0</accession>
    <name>A4RWP0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417612.1">
        <property type="nucleotide sequence ID" value="XM_001417575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWP0"/>
    <dbReference type="GeneID" id="5001273"/>
    <dbReference type="Gramene" id="ABO95905">
        <property type="protein sequence ID" value="ABO95905"/>
        <property type="gene ID" value="OSTLU_31404"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31404"/>
    <dbReference type="HOGENOM" id="CLU_2642535_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="77" mass="8771" checksum="2EAD9D0D355BD691" modified="2007-05-15" version="1">MNQAQKDRVKEIAEWLSESDAGRALWHIHFGRPMAENQPGAPGTLTPNRTISVALESEDVDIYGDIDKLREQLKDFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWT6</accession>
    <name>A4RWT6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_36881</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417389.1">
        <property type="nucleotide sequence ID" value="XM_001417352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWT6"/>
    <dbReference type="STRING" id="436017.A4RWT6"/>
    <dbReference type="GeneID" id="5001586"/>
    <dbReference type="Gramene" id="ABO95682">
        <property type="protein sequence ID" value="ABO95682"/>
        <property type="gene ID" value="OSTLU_36881"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36881"/>
    <dbReference type="eggNOG" id="KOG0458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_3_5_1"/>
    <dbReference type="OMA" id="VVQITCH"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000204">
        <property type="entry name" value="Translation elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="42"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="481" mass="51339" checksum="9A523854845FAEE0" modified="2007-05-15" version="1">METTETLVKEFAAKTRVGGDATAFAGYEASSAERAAYTSPEGGDVHVVILGHVDAGKSTLSGRLMYALKAVDDRAMHKNVRDSKASGKSSFAWAWVMDCRPEERERGVTIDVSMKRCVLDGHRQLVVLDAPGHKDFVPNAISGASQADAGVLVIDGAMGGFENGFAATPGHTGQTREHARLARALGLHSLIVVINKMDCVEYGEERFRFVVDALQNFLIDDVGFSQEQLTFVPVSGIEGTNISPDDAAALPDALASWYRGPTLVDALRAVKIPSRGAPKPLRMPIADIITEVRSLGGAACGGKIEAGSLMKGQKLLVMPANVSATVKCVEVDGIAVDFAPIGTSVDVGLSDVDSRHLEVGSVLCHASHPITPTDEIEVRVLTTDMLRVPLLKGSRVVLHSHMLACDATIEELVAQVDTVTGDVVKASPRCITREQSAILRIRTSRNICVEPVEISPTLSRVTLRMNGKTMALGVVTAIWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX10</accession>
    <name>A4RX10_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417915.1">
        <property type="nucleotide sequence ID" value="XM_001417878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX10"/>
    <dbReference type="GeneID" id="5001673"/>
    <dbReference type="Gramene" id="ABO96208">
        <property type="protein sequence ID" value="ABO96208"/>
        <property type="gene ID" value="OSTLU_31527"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31527"/>
    <dbReference type="HOGENOM" id="CLU_1743598_0_0_1"/>
    <dbReference type="OrthoDB" id="498665at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="150" mass="15667" checksum="D0D67484CDA1A268" modified="2007-05-15" version="1">MTTLVALASTSAPVARARTAVKCSAKKRSSVTPKIISEGGRATSQSSTQDDVPTPLSADKQRSLPPEMLVDDPWESESFEGLGNAAQYALLVIGIVAAGAGFYATSTYNEGAVEVDFQSYESPEEAVADSLRKVNALQAQSASAPSLEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX67</accession>
    <name>A4RX67_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oxa1 family transporter: 60 KD inner membrane protein OxaA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_3329</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC (TC 2.A.9.2) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417701.1">
        <property type="nucleotide sequence ID" value="XM_001417664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX67"/>
    <dbReference type="STRING" id="436017.A4RX67"/>
    <dbReference type="GeneID" id="5001902"/>
    <dbReference type="Gramene" id="ABO95994">
        <property type="protein sequence ID" value="ABO95994"/>
        <property type="gene ID" value="OSTLU_3329"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3329"/>
    <dbReference type="eggNOG" id="KOG1239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036138_4_1_1"/>
    <dbReference type="OMA" id="PHMKELQ"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072598">
        <property type="term" value="P:protein localization to chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20070">
        <property type="entry name" value="5TM_YidC_Alb3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047196">
        <property type="entry name" value="YidC_ALB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF14">
        <property type="entry name" value="ALBINO3-LIKE PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="8">
        <location>
            <begin position="47"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="264" mass="29091" checksum="D06588A45CAE4323" modified="2007-05-15" version="1" fragment="single">AAKIASGEIAAPQRMEGWLAPVSDALEDLLFAIQGQLQGLGVPYSTGNAIIIVTILVKFVTYPLTRDQVVSSLNMKNLQPQIAAIREKYEDDQERMNKEINRVYEENGVNPLAGCGPALLTFPVLAGLYRAFNNAGIDGAFDEAWFFLPSLAGPTDARDLSWLLPLDSDYAPPIGWEEASLYLIFPVLTTISQFVSMEVLKPEETEKTDEMKNQSVLLKLLPLFIGYISLTVPAGLALYWFWNNVFTTGIQVFLRNGGAKATVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX73</accession>
    <name>A4RX73_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_8083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417947.1">
        <property type="nucleotide sequence ID" value="XM_001417910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX73"/>
    <dbReference type="STRING" id="436017.A4RX73"/>
    <dbReference type="GeneID" id="5001906"/>
    <dbReference type="Gramene" id="ABO96240">
        <property type="protein sequence ID" value="ABO96240"/>
        <property type="gene ID" value="OSTLU_8083"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8083"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1772916_0_0_1"/>
    <dbReference type="OMA" id="IHRITCA"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="74"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="147" mass="15581" checksum="6CF7693E5EE743A8" modified="2007-05-15" version="1" fragment="single">LAPDLSFMITAATDGVMRLWKVASQPPTVTLEFRGHIGEITCTACASTGLFASSGVDSSIMLWEPRNAKHVGLIKAHDGPITALSFNRDGKLLVSASVDRTCKIHSSLTGKLIVSMNHIHRITCASISLDASCVVTGAGDGTMRLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXM5</accession>
    <name>A4RXM5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OCRE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417780.1">
        <property type="nucleotide sequence ID" value="XM_001417743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXM5"/>
    <dbReference type="STRING" id="436017.A4RXM5"/>
    <dbReference type="GeneID" id="5001731"/>
    <dbReference type="Gramene" id="ABO96073">
        <property type="protein sequence ID" value="ABO96073"/>
        <property type="gene ID" value="OSTLU_15464"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15464"/>
    <dbReference type="HOGENOM" id="CLU_1006081_0_0_1"/>
    <dbReference type="OMA" id="AYARGVC"/>
    <dbReference type="OrthoDB" id="147332at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd16165">
        <property type="entry name" value="OCRE_ZOP1_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041591">
        <property type="entry name" value="OCRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019367">
        <property type="entry name" value="PDZ-binding_CRIPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035622">
        <property type="entry name" value="ZOP1_OCRE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10235">
        <property type="entry name" value="Cript"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17780">
        <property type="entry name" value="OCRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OCRE" evidence="2">
        <location>
            <begin position="209"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="277" mass="29778" checksum="B64D6928104F2AAC" modified="2007-05-15" version="1">MVCAACERKRRARGDDALVHSRPMSRRDLALEGARALDARRPVNENKALAAMRRTPYGRPGERRATCAVCRCALRDGGTHCNACAYARGVCSGCGVKIMDVSAYNGHDAAATTTTNARDAAASVRDRADVSTEDVERKEAVKTRARVGTKATAMAKEEDEDEDEGEDAAEAEAEAETRAPPATSTALAGPTSAADAAREMGQAANGGEVSAWRLDTKSGYYYDVAAQVYYDPKTGGYFDCKTQQWTMPEKKTSSEIQKGIKTGSFKDGTRKPDRFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXR8</accession>
    <name>A4RXR8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Repressor of RNA polymerase III transcription</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_38480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417803.1">
        <property type="nucleotide sequence ID" value="XM_001417766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXR8"/>
    <dbReference type="STRING" id="436017.A4RXR8"/>
    <dbReference type="GeneID" id="5002116"/>
    <dbReference type="Gramene" id="ABO96096">
        <property type="protein sequence ID" value="ABO96096"/>
        <property type="gene ID" value="OSTLU_38480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38480"/>
    <dbReference type="eggNOG" id="KOG3104">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037043_3_1_1"/>
    <dbReference type="OMA" id="DKVCRKT"/>
    <dbReference type="OrthoDB" id="277029at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072718">
        <property type="term" value="P:response to cisplatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033194">
        <property type="term" value="P:response to hydroperoxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072702">
        <property type="term" value="P:response to methyl methanesulfonate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1000.50:FF:000003">
        <property type="entry name" value="Repressor of RNA polymerase III transcription MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037240">
        <property type="entry name" value="RNA_polIII_Trep_MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR037240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="251" mass="28211" checksum="1B6D02E9A592A539" modified="2007-05-15" version="1">MKLLVEPDVAALNAFLTNVNVGDYVVSGQVESYSCKLAGTDKKLSRSLDAEVVTEIVSSCSPTNLSTSPVGPLTDQNSRKTLIYLILTLNHIYPDYDFSSLRAEHFTKEGTLSDVKTDIDTLLMESSKVWAARYGNEEPFLEVLWKTIDAAIEVFDCDVYSYKAVAEGDPFTDDGNLWSFNYFFYNKKLKRILYFTMHATSKTMLDLDSDDELDLDESNDQTGGTGYNSYDGSYRESFGNDDSMVFDEMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY58</accession>
    <name>A4RY58_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="10">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_38679</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="10"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417873.1">
        <property type="nucleotide sequence ID" value="XM_001417836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY58"/>
    <dbReference type="STRING" id="436017.A4RY58"/>
    <dbReference type="GeneID" id="5001885"/>
    <dbReference type="Gramene" id="ABO96166">
        <property type="protein sequence ID" value="ABO96166"/>
        <property type="gene ID" value="OSTLU_38679"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38679"/>
    <dbReference type="eggNOG" id="KOG2951">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_1_0_1"/>
    <dbReference type="OMA" id="ERGLHPW"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="UniPathway" id="UPA00823">
        <property type="reaction ID" value="UER00788"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010347">
        <property type="term" value="F:L-galactose-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019853">
        <property type="term" value="P:L-ascorbic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000004">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000002">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0452">Lithium</keyword>
    <keyword evidence="8 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="30343" checksum="C71197978735CFFF" modified="2007-05-15" version="1">MDHERELRVAERAARVAGAEIARAWTRDRSNETSVEYKGAVDLVTATDKLCEDLVLSALREAFPEDDVVGEETHAASGAKELSKTTSVRCWYVDPLDGTTNFVHGYPFSCVSVGLCEGGEPTVGVVFNPISDEMFTAVRGRGAFLNGKKISCSAVRTLGKALIGTEIGVHRDGKTVDAIMGRVRALVEKSRSVRCSGSCAMNMCGVAMGRLDGFFEIGFGGPWDCVAGTIIVREAGGVVFDPSGDAFDIYARRVLCANGNIGDEFVKALSEVPDGPGEPQRPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYU1</accession>
    <name>A4RYU1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_41188</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418453.1">
        <property type="nucleotide sequence ID" value="XM_001418416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYU1"/>
    <dbReference type="STRING" id="436017.A4RYU1"/>
    <dbReference type="GeneID" id="5002402"/>
    <dbReference type="Gramene" id="ABO96746">
        <property type="protein sequence ID" value="ABO96746"/>
        <property type="gene ID" value="OSTLU_41188"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41188"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_4_2_1"/>
    <dbReference type="OMA" id="CANERGH"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000013">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="8"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="167" mass="18323" checksum="3AEF99BF52E1EC76" modified="2007-05-15" version="1" fragment="single">MSPLPRVFFDVAIGRERVGRITIELRSDVVPKTCENFRQLCANERGHRLSYADSTFHRVIPNFMIQGGDFTNHDGTGGESVYGPKFRDENFTLKHAGAGTLSMANAGPHTNGSQFFICTGDTPWLDGKHVVFGSVVDGMDVVRRVEACGSKSGKTRETVKIVECGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYV5</accession>
    <name>A4RYV5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HMGB3505</name>
        <name evidence="7" type="ORF">OSTLU_15773</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYV5"/>
    <dbReference type="STRING" id="436017.A4RYV5"/>
    <dbReference type="GeneID" id="5002383"/>
    <dbReference type="Gramene" id="ABO96752">
        <property type="protein sequence ID" value="ABO96752"/>
        <property type="gene ID" value="OSTLU_15773"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15773"/>
    <dbReference type="eggNOG" id="KOG0381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1350859_0_0_1"/>
    <dbReference type="OMA" id="NYEKLMY"/>
    <dbReference type="OrthoDB" id="550908at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Toprim_C_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF32">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN B3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13368">
        <property type="entry name" value="Toprim_C_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
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        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="126"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="126"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="69"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="203" mass="22281" checksum="489DF0D4C4092543" modified="2007-05-15" version="1">MFEYPKVLGVHPVTQAPVSLNIGPFGWYVASEVAGEVLRASIGKTVLKRVGAVENVDIDEAVELLRKKAERPPRTRGRYASKKTKAKKEPKKAKEPKPKKEPEAKKEAKYPKAKKAPKPKVEVPGMKKPLTAFFAFSADERASVKAENPTFKVGEVAKALGERWASLDPERKAKYESDAKTAKEAYAAALAEFSASSESSREP</sequence>
</entry>
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    <name>A4RZ68_OSTLU</name>
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            <fullName evidence="3">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_40957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418524.1">
        <property type="nucleotide sequence ID" value="XM_001418487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ68"/>
    <dbReference type="STRING" id="436017.A4RZ68"/>
    <dbReference type="GeneID" id="5002213"/>
    <dbReference type="Gramene" id="ABO96817">
        <property type="protein sequence ID" value="ABO96817"/>
        <property type="gene ID" value="OSTLU_40957"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40957"/>
    <dbReference type="eggNOG" id="KOG1808">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004483_0_0_1"/>
    <dbReference type="OMA" id="EYQIMVA"/>
    <dbReference type="OrthoDB" id="5186at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="147"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="39808" checksum="B080FFBBDF2455E1" modified="2007-05-15" version="1">MTERELVAGGEGETGEESTIALQLEHTSLGGAGEVVHELTPEDVELARIEAEQSLTQWREKSAKERGNEANAQNLWRKLEQLTTALSAELAEKLRLILEPTLASRLQGDYKTGKRLNMRKIIPYIASDFRKDKIWLRRSRPSARKYQVMLAIDDSRSMAENHCGHIALESMVLLARAMARLEVGEIGVVGFGAGANAVRTLHPLGAPFTDQEGPSLVSKLSFAEDNTLADRPMVQLLETMAARLSVAREQIRGGGTKLQQLVLIIADGRFHEKEALRRCMREVGAQRGLLVAFIVLDNPQNSLLNMQSVSFTGGKPVMKKYLDSFPFPFYVLVQDVSQLPATISDLLRQWFEMATSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZC3</accession>
    <name>A4RZC3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Calcium-dependent protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_49728</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418307.1">
        <property type="nucleotide sequence ID" value="XM_001418270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZC3"/>
    <dbReference type="STRING" id="436017.A4RZC3"/>
    <dbReference type="GeneID" id="5002187"/>
    <dbReference type="Gramene" id="ABO96600">
        <property type="protein sequence ID" value="ABO96600"/>
        <property type="gene ID" value="OSTLU_49728"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49728"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_37_3_1"/>
    <dbReference type="OMA" id="WAHISED"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="68"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="377"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="415"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="448"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="486"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="57498" checksum="1230A91D73B86EC4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZQ2</accession>
    <name>A4RZQ2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418610.1">
        <property type="nucleotide sequence ID" value="XM_001418573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZQ2"/>
    <dbReference type="GeneID" id="5003022"/>
    <dbReference type="Gramene" id="ABO96903">
        <property type="protein sequence ID" value="ABO96903"/>
        <property type="gene ID" value="OSTLU_32465"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32465"/>
    <dbReference type="eggNOG" id="ENOG502R34T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1484381_0_0_1"/>
    <dbReference type="OMA" id="FVCFYPA"/>
    <dbReference type="OrthoDB" id="1745547at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="182" mass="20054" checksum="F1EB45F4DDF24384" modified="2007-05-15" version="1">MIEDALKGDSDAKSIAAKCRACPGTLLLSAANMRAHAASKRHRKNLEKLGRANDETFVCFYPAVREDDGIVSDGEAETHAERLARLRAQKILRSAEGERAKGGKFSLDQFDSSGDEASDDESDGDDDAKMTKRLAKKEFARKVSDSAPKEKEKRSRRHAQSKRKSGKSKPGKRQRMAMKSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZU9</accession>
    <name>A4RZU9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_2530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418861.1">
        <property type="nucleotide sequence ID" value="XM_001418824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZU9"/>
    <dbReference type="STRING" id="436017.A4RZU9"/>
    <dbReference type="GeneID" id="5002654"/>
    <dbReference type="Gramene" id="ABO97154">
        <property type="protein sequence ID" value="ABO97154"/>
        <property type="gene ID" value="OSTLU_2530"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2530"/>
    <dbReference type="eggNOG" id="KOG1906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013572_0_0_1"/>
    <dbReference type="OMA" id="NAPNMLE"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000006">
        <property type="entry name" value="non-canonical poly(A) RNA polymerase PAPD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="8">
        <location>
            <begin position="65"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="7">
        <location>
            <begin position="265"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="347" mass="38171" checksum="8F234B24F1252C0F" modified="2007-05-15" version="1" fragment="single">IDFSYLDAAPIRNEPGSASATAVKALAVEEEEAEEEYFDPNENPRWCPPGTVKRLRNLQSPLIRLHTEIVDFSRYLEPTEEEATSRAAAVERVRAVVNGIWPDARFEVHGSFATGMYLPSSDIDAVILDSGAKNAGLCLKALAVALARRGMAIKIQLIAKARVPIVKFEEVESGHQFDISFDVANGPASAEIVRENMRRFPALRPLTTVLKAFLHQRGLNEVYSGGIGSYALLCMVMAHLQLHNTTCKSTWAGSHGASDASEGCLGTLLIDFFELFGRRLVAEEVGISCGGKGPGFFKKRDKGMYEDSRPFLWAIEDPQDETNDLGRNSYACRQVKSAFEHAFTVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZW8</accession>
    <name>A4RZW8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_32539</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418872.1">
        <property type="nucleotide sequence ID" value="XM_001418835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZW8"/>
    <dbReference type="STRING" id="436017.A4RZW8"/>
    <dbReference type="GeneID" id="5002958"/>
    <dbReference type="Gramene" id="ABO97165">
        <property type="protein sequence ID" value="ABO97165"/>
        <property type="gene ID" value="OSTLU_32539"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32539"/>
    <dbReference type="eggNOG" id="KOG3327">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_3_3_1"/>
    <dbReference type="OMA" id="YWHQFDA"/>
    <dbReference type="OrthoDB" id="425602at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000679">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="10">
        <location>
            <begin position="16"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="24534" checksum="8B7BC694A6FDEC19" modified="2007-05-15" version="1">MSAAGKVAARGAFVLFEGADRCGKSTQAMRLVHTLEARGVEAELWRYPDRATAMGKMIDQYLRSKSEMEDGAIHLLFAANRWEKKALMERKLASGVTLVCDRYSYSGCAFTAAKGVDGLDLEWCRAPEVGLPRPDALMYLELSLEDAAKRGGFGEERYETTEMQRAVKASFEAMREDWWDVIDANREPDVIQDEVLRIALSAVEKCRAGRELKRLWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S062</accession>
    <name>A4S062_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_35397</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Vacuole membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418919.1">
        <property type="nucleotide sequence ID" value="XM_001418882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S062"/>
    <dbReference type="STRING" id="436017.A4S062"/>
    <dbReference type="GeneID" id="5002970"/>
    <dbReference type="Gramene" id="ABO97212">
        <property type="protein sequence ID" value="ABO97212"/>
        <property type="gene ID" value="OSTLU_35397"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35397"/>
    <dbReference type="eggNOG" id="KOG0232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085752_1_2_1"/>
    <dbReference type="OMA" id="MGVMKPD"/>
    <dbReference type="OrthoDB" id="510079at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000003">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="91"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="159" mass="15880" checksum="55686DAD9292DEFA" modified="2007-05-15" version="1">MSTSDEVAPFFGFMGATSALVFSCMGAAYGTAKSGVGIASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVVISTNIDASSYTLFQGYAHLGSGLACGLSGLSAGMCIGIVGDAGVRANAQQPKLFVGVILILIFAEALALYGMIVGIILSSAASAATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S073</accession>
    <name>A4S073_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO96986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="Gramene" id="ABO96986">
        <property type="protein sequence ID" value="ABO96986"/>
        <property type="gene ID" value="OSTLU_32639"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32639"/>
    <dbReference type="HOGENOM" id="CLU_447882_0_0_1"/>
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    <dbReference type="OrthoDB" id="10427106at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="206"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="238"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="430"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="436"/>
            <end position="458"/>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="501"/>
            <end position="524"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="330"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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        </source>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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        <source>
            <dbReference type="EMBL" id="ABO96986.1"/>
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        <source>
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</entry>
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            <taxon>Mamiellophyceae</taxon>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ABO96992"/>
        <property type="gene ID" value="OSTLU_35581"/>
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        <property type="component" value="Chromosome 7"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="CHLOROPHYLLIDE A OXYGENASE, CHLOROPLASTIC"/>
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        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
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    </dbReference>
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        <property type="entry name" value="RIESKE"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="73"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="386" mass="42145" checksum="1DA8659B8A6734A5" modified="2007-05-15" version="1">MARATPAPAPAPATARARAEARGDAGRRSVAARARRARARAPVGAVVDDATTRARGARGVDGARRTRDARDYWFPVCFSGNLRDKDALVAFDLFNVPWVLFRGRDGEVGCVKDECCHRACPLSLGKVVDGRVQCPYHGWEYETNGECAKMPSCSFLKNVFADELRVIERDGMIFVWAGESDPADFVGPEAACESWDEDVYEANEPGMFTTGEGFVTMAEVIADVKLDSDVVVERLLDITERARREPVSVKNRGRGALFPVDGTRLISKVLRIGYDAVPQSVVFKPSCVIASTIALRPRVGGGDGTSMQVEQLHVCLPAKPGLTRVLFRMAFDFVPEGAQNAAGDVWKNLAMQVLQEELEDVRSAGLKSETTSIAVESFRVFKRGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0G9</accession>
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        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_35422</name>
    </gene>
    <organism evidence="7 8">
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
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                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
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                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
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                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in vesicular protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
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        <text evidence="2 6">Belongs to the VPS35 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C"/>
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        <property type="entry name" value="Vps35"/>
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        <property type="entry name" value="Vps35_C"/>
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        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009375">
        <property type="entry name" value="Retromer_Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="822" mass="91494" checksum="281B24EFDECE6296" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Y9</accession>
    <name>A4S0Y9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aldehyde dehydrogenase family 5 member F1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_42872</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>succinate semialdehyde + NAD(+) + H2O = succinate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13217"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419272.1">
        <property type="nucleotide sequence ID" value="XM_001419235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Y9"/>
    <dbReference type="STRING" id="436017.A4S0Y9"/>
    <dbReference type="GeneID" id="5003438"/>
    <dbReference type="Gramene" id="ABO97565">
        <property type="protein sequence ID" value="ABO97565"/>
        <property type="gene ID" value="OSTLU_42872"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42872"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OMA" id="IGELFCK"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000005">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="44"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00052498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00076033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="503" mass="52924" checksum="39CCC9BC6414F10D" modified="2007-05-15" version="1">MSTAGEDDDARRSALAAALKLRNANLLRFAGASATDASRGASRASETFEVKNPATNATLATVLSTPRAAISDVLRRSEDAQKVWATEFSAHARGKVIRRWFELVEANAEDLARIMTAEQGKPLIESRGEVAYAASFLEWFAEEGKRVYGDVVPSSSTGTRIMVVKQPVGVTAAITPWNFPLAMITRKAGAALAAGCSMVVKPSEETPLSAFALGVLAEQAGCPDGVLQFIVGDPSAIGAALCESPVVRKITFTGSTRVGKLLMKQSADTVKRVSMELGGNAPFVVCADADVDAAVQGAMASKFRNAGQTCVCAQRFIVHASVEAEFVQKLADAASALVMGDGLENEDATQGPLINAAHAEKVDSHVRDAMSKGAVCHTGGKRAHGSFYEPTVLSKCTEDMLVMREETFGPVAAVTTFVDDAEAIRIANATTAGLASYVYTSDVKRTFYFSEKLDFGIVGVNTGAISTAQAPFGGTKESGIGREGGKDGVHEYVEQKYVCVGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="109" xmlns="https://uniprot.org/uniprot">
    <accession>A4S140</accession>
    <name>A4S140_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pyruvate carboxylase</fullName>
            <ecNumber evidence="12">6.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">OSTLU_32964</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="function">
        <text evidence="2">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + pyruvate + ATP = oxaloacetate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="12"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419085.1">
        <property type="nucleotide sequence ID" value="XM_001419048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S140"/>
    <dbReference type="STRING" id="436017.A4S140"/>
    <dbReference type="GeneID" id="5003368"/>
    <dbReference type="Gramene" id="ABO97378">
        <property type="protein sequence ID" value="ABO97378"/>
        <property type="gene ID" value="OSTLU_32964"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32964"/>
    <dbReference type="eggNOG" id="KOG0369">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_1_0_1"/>
    <dbReference type="OMA" id="AEACICY"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016421">
        <property type="term" value="F:CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004736">
        <property type="term" value="F:pyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07937">
        <property type="entry name" value="DRE_TIM_PC_TC_5S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000003">
        <property type="entry name" value="Acetyl-CoA carboxylase biotin carboxyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000018">
        <property type="entry name" value="Biotin carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000033">
        <property type="entry name" value="Pyruvate carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.600.10">
        <property type="entry name" value="pyruvate carboxylase f1077a mutant domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055268">
        <property type="entry name" value="PCB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005930">
        <property type="entry name" value="Pyruv_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
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    <sequence length="1132" mass="122997" checksum="587D87D1FD53BBF0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S168</accession>
    <name>A4S168_OSTLU</name>
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        <submittedName>
            <fullName evidence="8">DMT family transporter: drug/metabolite</fullName>
        </submittedName>
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    <gene>
        <name evidence="8" type="ORF">OSTLU_5328</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">CCE9901</strain>
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            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <text evidence="2">Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.</text>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="AA-Vitamin_Transporters"/>
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        <property type="entry name" value="EmrE-like"/>
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        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00892"/>
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        <source>
            <dbReference type="EMBL" id="ABO97604.1"/>
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    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="300" mass="31245" checksum="F6548DC4A4FB733F" modified="2007-05-15" version="1" fragment="single">LALVSPFFLWGTSMVAMKGVLPVTSPMFVASVRLIPSGLILVAWALSKGRPMPKTATAWGAVAAFAVVDAAMFQGFLAEGLQRTSAGLGSVIIDSQPLTVAILASIFFGETLGVEGVAGLALGVLGLLLLELPEDALKSVVNSDGADALSALRLEGSLWDSGEWWMLLAAQSMAVGTVMVRWVCKYVDPVMATGWHMALGGVPLLAYSLATEPELYSHLSLSGADVASLLYASVFGGAVAYGAFFYFATKGSLTKLSSLTFLTPMFAAALGYLTLDETLSATQLGGAAVTLVGIYFVNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1A4</accession>
    <name>A4S1A4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferritin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_4617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419330.1">
        <property type="nucleotide sequence ID" value="XM_001419293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1A4"/>
    <dbReference type="GeneID" id="5003419"/>
    <dbReference type="Gramene" id="ABO97623">
        <property type="protein sequence ID" value="ABO97623"/>
        <property type="gene ID" value="OSTLU_4617"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4617"/>
    <dbReference type="eggNOG" id="ENOG502QU9I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035354_2_0_1"/>
    <dbReference type="OMA" id="LAWDTIV"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007402">
        <property type="entry name" value="DUF455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011197">
        <property type="entry name" value="UCP012318"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782:SF4">
        <property type="entry name" value="DUF455 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782">
        <property type="entry name" value="SI:CH73-314G15.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04305">
        <property type="entry name" value="DUF455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012318">
        <property type="entry name" value="UCP012318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="34766" checksum="C12C986B6BD1DCF9" modified="2007-05-15" version="1" fragment="single">ARSRAQWDGLERWREKALDARRAWGDGDEPTTTADARARDDGGDARALASRAREIVATACPREKARLSHVAYGLLVRGKIDIADATTRASDMPTRPARPAKPRLVPPKEVPSPKNSPLGAAAHAMHTVTHIELNAIDLAWDTVGRFADLRGALPDQFFVDFAHVADDESRHLLWCLQRLEELGVAYGDVAAHDVLWEGCEATRDDPLARLAVVPCMQEARGLDAGPRLVERLVGHGDARSAAIVARISEEEIAHVAVGATWFRTVCAALGDDDDDARADDVAAATFRAYIQRLAPDALRGPFNHDDRARAGIDPSWYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1C4</accession>
    <name>A4S1C4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419125.1">
        <property type="nucleotide sequence ID" value="XM_001419088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1C4"/>
    <dbReference type="GeneID" id="5003290"/>
    <dbReference type="Gramene" id="ABO97418">
        <property type="protein sequence ID" value="ABO97418"/>
        <property type="gene ID" value="OSTLU_16436"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16436"/>
    <dbReference type="HOGENOM" id="CLU_861639_0_0_1"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="323" mass="33683" checksum="A34810DEDC125D76" modified="2007-05-15" version="1">MVCALRFATQGACFRENCRYAHDAAEGAAVPTQTTQPVCRDYQNGRCFRASCRFYHGSNAEQVAVQLGAGNRMFPGSINGAQGMYGAATGDLLHNKNPQLHMMNRTMNLPMNMVGNPDPAALLGADASTAALLGGNLSLEQALFLQTAMANGTAYDNNAALTAVAMANEILRRNAAGQQAPNGNYDMSSMYAQQMATVVAQQQAALAQQMAAANGQLTNGGFAPLNNGEKLSKDAGVGGAYQQAVAAASAAMNNPSAPGEQFSWTGIEYATNGVHQQNQFKPVDSIAALPDSLVDNDLFGFVNSEMSNAAAAFVPGSALGNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1G5</accession>
    <name>A4S1G5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419145.1">
        <property type="nucleotide sequence ID" value="XM_001419108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1G5"/>
    <dbReference type="GeneID" id="5003248"/>
    <dbReference type="Gramene" id="ABO97438">
        <property type="protein sequence ID" value="ABO97438"/>
        <property type="gene ID" value="OSTLU_33091"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33091"/>
    <dbReference type="HOGENOM" id="CLU_110464_0_0_1"/>
    <dbReference type="OMA" id="RREYRIN"/>
    <dbReference type="OrthoDB" id="544623at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23586" checksum="7C54EBDAA8D8C58F" modified="2007-05-15" version="1">MPTLVNTRAVVTSEHVSTSTPRARGAASRVTVAHASSFSRNVCASSLALLVNFTQANVAFAAPAAPSYSGVDPSKSSFIQGLVDKSEKDKAKNDQARLDNFYRREYRINRIVGGEVLKEPCDPRDPEFGYECRPMLPRLPQDRGGFDEPLEREKTGYGKVLGTRDVDRAADALVAAAVDETLERAIETIDGESDANGDAVARFDSDTEFSPSVQGLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1P8</accession>
    <name>A4S1P8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_93153</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419405.1">
        <property type="nucleotide sequence ID" value="XM_001419368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1P8"/>
    <dbReference type="STRING" id="436017.A4S1P8"/>
    <dbReference type="GeneID" id="5003162"/>
    <dbReference type="KEGG" id="olu:OSTLU_93153"/>
    <dbReference type="eggNOG" id="KOG4547">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106457_0_0_1"/>
    <dbReference type="OMA" id="HWIIVTH"/>
    <dbReference type="OrthoDB" id="30195at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="5">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="21318" checksum="273E78A2B561E649" modified="2007-05-15" version="1" fragment="single">LIERCLSVSDRTTIANTVAKLSSTHAMKLLSECAARAQAKPNSGERCAKWARTILLHHAGYASSAPKARTTLMRLSQTIESHVAMQGPLQALLGRLELVLHASAMTKGGADDVDELADAEETLTTVYDEATDAVDILQDVMGRERAGASQDVEDEEGDEDDESEEEDESEDESEDESEDDEEDEEDESEEEGDGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2G5</accession>
    <name>A4S2G5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome c peroxidase, mitochondrial</fullName>
            <ecNumber evidence="5">1.11.1.11</ecNumber>
            <ecNumber evidence="13">1.11.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_4354</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.11" evidence="5"/>
    <dbReference type="EC" id="1.11.1.5" evidence="13"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419746.1">
        <property type="nucleotide sequence ID" value="XM_001419709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2G5"/>
    <dbReference type="STRING" id="436017.A4S2G5"/>
    <dbReference type="GeneID" id="5003747"/>
    <dbReference type="Gramene" id="ABO98039">
        <property type="protein sequence ID" value="ABO98039"/>
        <property type="gene ID" value="OSTLU_4354"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4354"/>
    <dbReference type="eggNOG" id="ENOG502QR1E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036959_0_0_1"/>
    <dbReference type="OMA" id="NDCTDEG"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016688">
        <property type="term" value="F:L-ascorbate peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000009">
        <property type="entry name" value="Ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="17">
        <location>
            <begin position="47"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00039063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO98039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="243" mass="26536" checksum="5DA509A5C39E17F6" modified="2007-05-15" version="1" fragment="single">DADFGPTLVRLAWHSSGTYDRMGKTGGSGGGTIRFKEELAHGGNAGLDKAIAKLEPIKKRHPDVSWADLIAFVGVVAIEEMGGPKLKFSYGRVDEMDPEAVTPDGRLPDADKGDGPGPKTRQGLRDVFYRMGFDDREIVALSGAHALGRCHADASGYVGPWSGTPLLFNNSYFVLLKGLKWEPNPDAKKFQYKDPSGNLMMLPSDIALIEDADFKKYVDVYAKSQKVFFEDFAAAFEKLETLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2H1</accession>
    <name>A4S2H1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419530.1">
        <property type="nucleotide sequence ID" value="XM_001419493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2H1"/>
    <dbReference type="GeneID" id="5003647"/>
    <dbReference type="Gramene" id="ABO97823">
        <property type="protein sequence ID" value="ABO97823"/>
        <property type="gene ID" value="OSTLU_25031"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25031"/>
    <dbReference type="HOGENOM" id="CLU_576703_0_0_1"/>
    <dbReference type="OMA" id="HERVWHE"/>
    <dbReference type="OrthoDB" id="10645965at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="474" mass="52117" checksum="E3DB48075A538407" modified="2007-05-15" version="1">MPGGAEDAACAATRVRGELNASWPRGRTPASGSTPLVALAKNMSSVLQHFEAVKTTDADDETTQVASLRAFSEREVVVDVYDRSGGATRAVREKLGAVGGTRVREARDASGDGDVGLVVVDGQEEESFEAIGKILKQSGVASTRVIVLVYGAAVGTLEEARARAARETRAPIENVFATFGILDESTSERLDSLLKNPPLRSTLETSAEVRVSVPEPVSAFALDDEDEDEDEGLTSIALSDAKVEREEWETIVREHAERCFEDAVDATMEQTRQFCLRRAEKLALQYEPLRSSLYQRIRGERSKTKIVEPSIQARVAPPSQYVEEMTTTRPYKLNSAASQPLGIDMIKLQSVAISGVEQGAVVASQAAEKVGSFLNWIVSENEESEDERRRRVEHERVWHERRQKLWDAERAQRVETQNRGKHSPTASFVETTSKLVDIIDGSLGGESQLDQANARIRALEAALARYDPSHELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2R0</accession>
    <name>A4S2R0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_33536</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HscB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419576.1">
        <property type="nucleotide sequence ID" value="XM_001419539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2R0"/>
    <dbReference type="STRING" id="436017.A4S2R0"/>
    <dbReference type="GeneID" id="5003782"/>
    <dbReference type="Gramene" id="ABO97869">
        <property type="protein sequence ID" value="ABO97869"/>
        <property type="gene ID" value="OSTLU_33536"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33536"/>
    <dbReference type="eggNOG" id="KOG3192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068529_0_2_1"/>
    <dbReference type="OMA" id="ACEGMTI"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="entry name" value="HscB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021:SF15">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="HSC20 (HSCB), C-terminal oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="72"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="25881" checksum="DE23B462F9796327" modified="2007-05-15" version="1">MANALRRLATASSRVALSRVAAGAPRAFVSDASATATPCWSCDARTTALNDDASANFFCDACGAIQPPVAADYFALLGVEPKYALESAALEDAMKRRQKLLHPDKFSTKSERERRYSADQASAVNEAYGTLRDPLRRAKYILEARGWGVTERDGRDAPVDPGLLMEVMEAREAIDEANGDAEKLRELLREHSARVTACEEETRAALDATPMVGESAKEAVVRLTYFVRIVEEIKALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2X6</accession>
    <name>A4S2X6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Diphthine--ammonia ligase</fullName>
            <ecNumber evidence="1">6.3.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Diphthamide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diphthamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_6853</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphthine-[translation elongation factor 2] + NH4(+) + ATP = diphthamide-[translation elongation factor 2] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10174"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16692"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.14"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.3.1.14" evidence="1"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419822.1">
        <property type="nucleotide sequence ID" value="XM_001419785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2X6"/>
    <dbReference type="STRING" id="436017.A4S2X6"/>
    <dbReference type="GeneID" id="5003824"/>
    <dbReference type="Gramene" id="ABO98115">
        <property type="protein sequence ID" value="ABO98115"/>
        <property type="gene ID" value="OSTLU_6853"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6853"/>
    <dbReference type="eggNOG" id="KOG2316">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010289_0_0_1"/>
    <dbReference type="OMA" id="NYALYWA"/>
    <dbReference type="OrthoDB" id="498766at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017178">
        <property type="term" value="F:diphthine-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="AANH_PF0828-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1490.10">
        <property type="entry name" value="putative n-type atp pyrophosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00290">
        <property type="entry name" value="MJ0570_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196:SF2">
        <property type="entry name" value="DIPHTHINE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthamide synthase" evidence="6">
        <location>
            <begin position="56"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="215" mass="23207" checksum="377976C15C5B13BC" modified="2007-05-15" version="1" fragment="single">VACLVNLCPRDAATREVDSHCFQTVAHECVGAFAACAGLDVYRRRITGRSKALGLEYGDGEEGDEVEDLRAALAAAKRERPDVNSVCSGAILSDYQRLRVEAVCASLGLTSLAPLWRVEQREVLRRVEAEGVDARLVKVAAMGLDPGKHLGMSIADARETLIRVEDEYGSHCAGEGGEFETLVVDCPMFARASLAITETRTVKTSEDRFAPSGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S311</accession>
    <name>A4S311_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Pyruvate, phosphate dikinase</fullName>
            <ecNumber evidence="3 11">2.7.9.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_16882</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>pyruvate + phosphate + ATP = phosphoenolpyruvate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10756"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.1" evidence="3 11"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419632.1">
        <property type="nucleotide sequence ID" value="XM_001419595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S311"/>
    <dbReference type="STRING" id="436017.A4S311"/>
    <dbReference type="GeneID" id="5003840"/>
    <dbReference type="Gramene" id="ABO97925">
        <property type="protein sequence ID" value="ABO97925"/>
        <property type="gene ID" value="OSTLU_16882"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16882"/>
    <dbReference type="eggNOG" id="ENOG502QREJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015345_0_2_1"/>
    <dbReference type="OMA" id="MREHNPM"/>
    <dbReference type="OrthoDB" id="10340769at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.189.10">
        <property type="entry name" value="Pyruvate Phosphate Dikinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
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        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004531">
        <property type="entry name" value="PRK05878.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01828">
        <property type="entry name" value="pyru_phos_dikin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE DIKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931:SF9">
        <property type="entry name" value="PYRUVATE, PHOSPHATE DIKINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000853">
        <property type="entry name" value="PPDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="16">
        <location>
            <begin position="3"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="16">
        <location>
            <begin position="291"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme mobile" evidence="15">
        <location>
            <begin position="416"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme C-terminal" evidence="17">
        <location>
            <begin position="518"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="12">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="835"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="615"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="748"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="748"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="770"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="771"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="772"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="773"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="773"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048103"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO97925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="895" mass="97679" checksum="949B54EC2CFB43B4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S340</accession>
    <name>A4S340_OSTLU</name>
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        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_88314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88314"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arg_MeTrfase"/>
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        <property type="entry name" value="Methyltransf_25"/>
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    <dbReference type="InterPro" id="IPR029063">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF4">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="66"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="542" mass="59107" checksum="9E673365A2C247BD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S382</accession>
    <name>A4S382_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_34809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">CCE9901</strain>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50033"/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="312" mass="34378" checksum="7582AEF44C02E772" modified="2007-05-15" version="1">MFHDGDTSRGVHFVQLSHREAVAFAQRETKLLFVYLHAPAHHESELFCAQVLADPTMTAYVNQNFVAWGGNVRDGDAFSLSAGLKPTGYPCVAILDSVSGGSGSASLVMSCEGFIDVDVLISACEEALAGQNASLDDARARHAEVDASRRLREEQDAAFAESLARDAARARELDAQREAEEAERRRVEEERRAVEEETKKAEEAERQRVEEIEARRASKASKLRDEPADGADGVSKLAVRLPDGSRAERRFHSTDTIADVYDFVDTLEELDEVSYSLVTNFPRRTFARSERVSLVDAGVHPNGAMFVQTESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="304" mass="33078" checksum="ED445693E373045F" modified="2007-05-15" version="1">MASPFGDAGAAKTSVDPFASSASRSRTSEATTTRAKNAVDATPRARAPAYRAWDDVEVFEVPETLRRDGAARNERFVEHVSLEGLFGATFADAFHDDASFRTDVRRAMRKDLFVPDENLSAEANAAMSALSSSVHVNWFESRTGYAALSALFASRGIEDVTGERFIRALGGLCGEPRHGTLIDIASPVGARKISHSWHQDSGYDRLTVMLGFPAAAPSESMGLPSGVGVFSHAVKLSHALRRPSPPGAVLQWEDVASARDVRLDARFVARPAFARHREIIVYRDSSILHSAPDVAHREAVWRFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3F4</accession>
    <name>A4S3F4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="3" type="ORF">OSTLU_16992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3F4"/>
    <dbReference type="GeneID" id="5004145"/>
    <dbReference type="Gramene" id="ABO98378">
        <property type="protein sequence ID" value="ABO98378"/>
        <property type="gene ID" value="OSTLU_16992"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16992"/>
    <dbReference type="HOGENOM" id="CLU_496619_0_0_1"/>
    <dbReference type="OMA" id="ANCDAKH"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="351"/>
        </location>
    </feature>
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        <location>
            <begin position="460"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
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        <location>
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            <end position="301"/>
        </location>
    </feature>
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        <location>
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            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="549" mass="61331" checksum="52BB3E6F0F9995AF" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3I5</accession>
    <name>A4S3I5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">THIF-type NAD/FAD binding fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_38170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesA/MoeB/ThiF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419924.1">
        <property type="nucleotide sequence ID" value="XM_001419887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3I5"/>
    <dbReference type="STRING" id="436017.A4S3I5"/>
    <dbReference type="GeneID" id="5004256"/>
    <dbReference type="Gramene" id="ABO98217">
        <property type="protein sequence ID" value="ABO98217"/>
        <property type="gene ID" value="OSTLU_38170"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38170"/>
    <dbReference type="eggNOG" id="KOG2017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_10_3_1"/>
    <dbReference type="OMA" id="EVACATM"/>
    <dbReference type="OrthoDB" id="10261062at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042292">
        <property type="term" value="F:URM1 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00757">
        <property type="entry name" value="ThiF_MoeB_HesA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000080">
        <property type="entry name" value="Thiazole biosynthesis adenylyltransferase ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF102">
        <property type="entry name" value="ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="33"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="268" mass="27962" checksum="1CB7D5FA9D96F225" modified="2007-05-15" version="1" fragment="single">MPAETETARKYHIVGDYATALNPRNDARSVEKYARHLVLRPHGARIQRALCAARVLVVGCGGLGCPCAIYLAASGVGTLGLCDADAVELSNLHRQVGHSTAATGTSKAKSLAARCEGLNDGVRVVVRETFATTENVMELVAGYDLVCDCSDNPRTRYLLSDACASAEIPLVSAACVGFEGQLTVLCGTRAWNDDDESFGEFAPAPCYRCLFPTPPASGDAGTCGASGVLGPLPGIVGTFQALEAMKTLAGVGESMRGKMLTFDALSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3L6</accession>
    <name>A4S3L6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420115.1">
        <property type="nucleotide sequence ID" value="XM_001420078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3L6"/>
    <dbReference type="STRING" id="436017.A4S3L6"/>
    <dbReference type="GeneID" id="5004274"/>
    <dbReference type="Gramene" id="ABO98408">
        <property type="protein sequence ID" value="ABO98408"/>
        <property type="gene ID" value="OSTLU_25132"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25132"/>
    <dbReference type="eggNOG" id="ENOG502QQTM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041607_0_0_1"/>
    <dbReference type="OMA" id="CPGFMRF"/>
    <dbReference type="OrthoDB" id="25131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038925">
        <property type="entry name" value="At3g17800-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008479">
        <property type="entry name" value="DUF760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31808">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31808:SF4">
        <property type="entry name" value="LIGASE, PUTATIVE (DUF760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05542">
        <property type="entry name" value="DUF760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="441" mass="47418" checksum="DF0547B953D70182" modified="2007-05-15" version="1">MATATIGRATLEATRARARATATRARGRWDAGRAARARATGRARATGRGDGFGDAETNPAAGLKAPSTPESPRGQQLAYILRTAPEMFDAAVDSQLDGLGEEVEREAKSASEEAKTEQLVLFKRIADVRALERRNGLEDIMYTTIIQKFLSVGVDMLPPLDETTMLKGIDLNRLTDGVHSKEALDMVREHLMAVLGGAGENAYSSQLVRMSKLQAAQVYAASIMFGYFVTRADKRFQLDRMVGTLPMDPMESAMALERLFNSASAMDSIDEADAAPQNFGGEDFDLFSDSAPSSGTGSQLTLKQYIQNFDQSTLAQTARIVSMEGVQVAERQTGALFGSIEDLQREMQDAVGMNAVTPEELMDAVNDAVAEKKVQTLTLAYASQRRLVLEAVAFGAFLRQSETYIDGYNPKLLTPTPRGPTGPPGASLPSGDDDDGGSPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3N4</accession>
    <name>A4S3N4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_38300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420123.1">
        <property type="nucleotide sequence ID" value="XM_001420086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3N4"/>
    <dbReference type="STRING" id="436017.A4S3N4"/>
    <dbReference type="GeneID" id="5004077"/>
    <dbReference type="Gramene" id="ABO98416">
        <property type="protein sequence ID" value="ABO98416"/>
        <property type="gene ID" value="OSTLU_38300"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38300"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="WLEVENC"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="276" mass="31135" checksum="26DE1C7243FDB6E7" modified="2007-05-15" version="1" fragment="single">MERYDDLESLGAGGFSVVRKVRHRQSAKTYAMKIISDEHGKERMSVNEVTSEIDILRVLTSPTMLRLEECHWYGDKVYVVTEVLHGGAVLDAILRMKSERYTEAEAKVVVQRTVQGIDYMHKNFVLHRDLKLENLLLRSNDDLASVVIADFGLARRCQNPEGLGSLPHSRGIDTAPVGTPVFAAPEVVEQKSYGGAIDMWSLGVITYVLLTGAMPRSLWKSALKYGRVVQRDFGFDCFEWDSVSETAREFVMSCLAHKPVHRLTPANCLKHPWLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Z1</accession>
    <name>A4S3Z1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420004.1">
        <property type="nucleotide sequence ID" value="XM_001419967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Z1"/>
    <dbReference type="STRING" id="436017.A4S3Z1"/>
    <dbReference type="GeneID" id="5003963"/>
    <dbReference type="Gramene" id="ABO98297">
        <property type="protein sequence ID" value="ABO98297"/>
        <property type="gene ID" value="OSTLU_26221"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26221"/>
    <dbReference type="eggNOG" id="ENOG502QTZK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067435_0_0_1"/>
    <dbReference type="OMA" id="FKDKGAC"/>
    <dbReference type="OrthoDB" id="1153057at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008930">
        <property type="term" value="F:methylthioadenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09008">
        <property type="entry name" value="MTAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044580">
        <property type="entry name" value="MTAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46994:SF1">
        <property type="entry name" value="5'-METHYLTHIOADENOSINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46994">
        <property type="entry name" value="5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="248" mass="26203" checksum="B182907172741A96" modified="2007-05-15" version="1">MAPIARVAVLFAMDAEARPLIDALGLTLDADAFARVGGDVPMRVYSGTLKSGARVDVVCAGSCARHNVCNVGTVGAALSTYETCATLRPDVIVNAGTAGGFAKRGGEVGDVYVATKFKNHDRRIPIPGYDKYGVGEYDAWPTPRLIEALGCKTGVVCTGNSLDATETCRALLDEFECSVKEMEAAAIAHVAHLFNVPVIAVKTITDIVDGPQATEEEFLRNLSSAADALRDVVPRVVEFLDGKSVDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4S404</accession>
    <name>A4S404_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420184.1">
        <property type="nucleotide sequence ID" value="XM_001420147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S404"/>
    <dbReference type="GeneID" id="5004101"/>
    <dbReference type="Gramene" id="ABO98477">
        <property type="protein sequence ID" value="ABO98477"/>
        <property type="gene ID" value="OSTLU_26235"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26235"/>
    <dbReference type="HOGENOM" id="CLU_3127594_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="50" mass="5896" checksum="C8E6B8A140A0D1B4" modified="2007-05-15" version="1">MSLSSPRVRRSADLSRQRRPLNRRFERRVAVEFRVPSLDERFVRAAPGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4M1</accession>
    <name>A4S4M1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420289.1">
        <property type="nucleotide sequence ID" value="XM_001420252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4M1"/>
    <dbReference type="STRING" id="436017.A4S4M1"/>
    <dbReference type="GeneID" id="5004586"/>
    <dbReference type="KEGG" id="olu:OSTLU_17308"/>
    <dbReference type="HOGENOM" id="CLU_1291903_0_0_1"/>
    <dbReference type="OrthoDB" id="6922at13792"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="215" mass="24046" checksum="60FAEB02A2C06AF8" modified="2007-05-15" version="1" fragment="single">MFLADAVEAKDLPGLAERMRERLRTMKENYHDITSYEGLRQRKKGALKAAKKMDLLRAAFNVDEAPKDACPMPTHKSDKPLKRKREYRILGTKMLCAGVCFLVLLMIPFLVTQYEEHEHHTGCDSISQGMIKLDHASSGQLEVNLLVGPCTYNASDFHMSYNIYQSYNHHTYQLGALGKPLTTPHWSAASSGHRRKLLGGGGAGVSKHVKASFET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4M2</accession>
    <name>A4S4M2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ArsB family transporter: P-protein-like protein (Tyrosine transporter)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_13038</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CitM (TC 2.A.11) transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420290.1">
        <property type="nucleotide sequence ID" value="XM_001420253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4M2"/>
    <dbReference type="STRING" id="436017.A4S4M2"/>
    <dbReference type="GeneID" id="5004358"/>
    <dbReference type="Gramene" id="ABO98583">
        <property type="protein sequence ID" value="ABO98583"/>
        <property type="gene ID" value="OSTLU_13038"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13038"/>
    <dbReference type="eggNOG" id="KOG2639">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011920_4_0_1"/>
    <dbReference type="OMA" id="MIREISW"/>
    <dbReference type="OrthoDB" id="442352at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01116">
        <property type="entry name" value="P_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000802">
        <property type="entry name" value="Arsenical_pump_ArsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051475">
        <property type="entry name" value="Diverse_Ion_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43568">
        <property type="entry name" value="P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43568:SF1">
        <property type="entry name" value="P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00758">
        <property type="entry name" value="ARSENICPUMP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="9">
        <location>
            <begin position="14"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="447" mass="48663" checksum="F83635828D0D0849" modified="2007-05-15" version="1">MWLGLVLLISIFGLIITEIIHRTLVAFIGAAAVLFILSLQHRLPSIATILTWMDHGTLALLFGMMIIVALLSRTGVFEYISVHIVEYSKGSMWRLFFMLMIFDAVLSAFLDNVTTMLLLAPVALSLCKALNIDPRPLLIPLSIFGNIGGCSTLIGDPPNIIIGNALKEHIGFVDFLRVLGPGVLLTMPFIFAFVKWYYGDALFGQKINVDIDELRAKYPIRDMNLLIRSGTILIFVILLFFLHPVMHMEPAYVAVFGAIAILLTGSHDEFEYALEKVEWDSLLFFAGLFVFTEGIAKLGLLRAIADELSTLIASFPIGQRQIGAMLLVELVAGIASAFVDNIPFTTTMLPVIIQMSENVQGISIEALAWALCFGADFGGIGTLIGSSANIVMAGIAAEAGFPITFKSFFRIGWPVMCISLCIAGAYLAALEGAGTFKVKDDDSASYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4N2</accession>
    <name>A4S4N2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_43938</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO98590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4S4N2"/>
    <dbReference type="GeneID" id="5004365"/>
    <dbReference type="Gramene" id="ABO98590">
        <property type="protein sequence ID" value="ABO98590"/>
        <property type="gene ID" value="OSTLU_43938"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43938"/>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_15_0_1"/>
    <dbReference type="OMA" id="HWFPFVG"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
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        <property type="component" value="Chromosome 11"/>
    </dbReference>
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        <property type="term" value="F:heme binding"/>
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    </dbReference>
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        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673061" evidence="7">
        <location>
            <begin position="17"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="471" mass="53441" checksum="EDDBC09009EE916D" modified="2007-05-15" version="1">MTVVIFIFLLDQLSHGPLKGRKSPPVIDVAPVWGGMLAFLAGPMKLMREATPKYGEVFTVPVFHKRITFLIGPKVSEFFFKAKDTEMSQKEVYEFNVPTFGKGVVFDVDHTTRAEQFRFFADSLKSNRLRMYVGMMVKEAEDFFSKWGDAGEVDLLEQLSELIVLTASRCLLGREIRETLYSEVTDLVHDLDKGMVPLSVFFPYAPIEAHRKRDAARKNLAKIFDKVIQARRESGASEPDVLQTFIDARYKDGSRLTNDQVLGMLIAVLFAGQHTSSITSTWTGLLAIANKERVMPALEKEQKDIMKKHGKDLDFDILAKMDELHFAVKEALRMHPPLIMLLRMAQVPFEVETSTGKKYTVPKGHIVATSPAFSHRLDNVYSDPNEYKPERFREPNPEDKAQFASFIGFGGGRHGCMGETFAYMQIKTIWSILLRNFEFEMVGKVPEPDYTGMVVGPTAGQCKIRYKRRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S569</accession>
    <name>A4S569_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_7602</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420719.1">
        <property type="nucleotide sequence ID" value="XM_001420682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S569"/>
    <dbReference type="STRING" id="436017.A4S569"/>
    <dbReference type="GeneID" id="5004737"/>
    <dbReference type="Gramene" id="ABO99012">
        <property type="protein sequence ID" value="ABO99012"/>
        <property type="gene ID" value="OSTLU_7602"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7602"/>
    <dbReference type="eggNOG" id="KOG0148">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_15_5_1"/>
    <dbReference type="OMA" id="ANSAIRC"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="3"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="98"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="161" mass="17274" checksum="E050DCF2107D33CD" modified="2007-05-15" version="1" fragment="single">DDRKIYVGHLPNNATADALADAFKSIGGVQDVACIPDAALGYSCKGFAFITFATVEQAKSAATSMNGALFGDRPMEVRLKTAPREEPRRDSGSFDPDANLYVGGMTESMTEESLREIFAPYGLVQKTKLIRDHATQVPKGYGFVQMMDVSHAHAAIAALDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5I6</accession>
    <name>A4S5I6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_39458</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420615.1">
        <property type="nucleotide sequence ID" value="XM_001420578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5I6"/>
    <dbReference type="GeneID" id="5004614"/>
    <dbReference type="Gramene" id="ABO98908">
        <property type="protein sequence ID" value="ABO98908"/>
        <property type="gene ID" value="OSTLU_39458"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39458"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_0_3_1"/>
    <dbReference type="OMA" id="WVAIFDE"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010150">
        <property type="term" value="P:leaf senescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046467">
        <property type="term" value="P:membrane lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901031">
        <property type="term" value="P:regulation of response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046686">
        <property type="term" value="P:response to cadmium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009644">
        <property type="term" value="P:response to high light intensity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990641">
        <property type="term" value="P:response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF115">
        <property type="entry name" value="PROTEIN ACTIVITY OF BC1 COMPLEX KINASE 8, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="146"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="660" mass="74044" checksum="83435F81066BA669" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5L8</accession>
    <name>A4S5L8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type E3 ubiquitin transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_5242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420631.1">
        <property type="nucleotide sequence ID" value="XM_001420594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5L8"/>
    <dbReference type="STRING" id="436017.A4S5L8"/>
    <dbReference type="GeneID" id="5004661"/>
    <dbReference type="Gramene" id="ABO98924">
        <property type="protein sequence ID" value="ABO98924"/>
        <property type="gene ID" value="OSTLU_5242"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5242"/>
    <dbReference type="eggNOG" id="KOG1813">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050460_1_0_1"/>
    <dbReference type="OMA" id="RGMNNYQ"/>
    <dbReference type="OrthoDB" id="25761at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034247">
        <property type="term" value="P:snoRNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16539">
        <property type="entry name" value="RING-HC_RNF113A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039971">
        <property type="entry name" value="CWC24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 113B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930">
        <property type="entry name" value="ZINC FINGER PROTEIN 183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="177"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="26760" checksum="4E3453CA80287F95" modified="2007-05-15" version="1" fragment="single">FAFEGSKTVRARGDMGATAELEIDTSKEMDGRAMREQVLKQAIDRADGFEDDKKYRGTNAYVDYRAGFRREQTISSEKGRGAHGPMRAATNIRSTFVMDYKPDICKDYKQTGFCGWGDACKFLHDRGDYKQGWQLDKDWEQKEQARKAAEARMAKLGEDGVAEESDEEYVNDIPESCAICDTSWLEAKFPVATACGHFFCERCALQHNAKQTTCFTCDKETGGTFNAAKEIIKRVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S618</accession>
    <name>A4S618_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_26958</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420866.1">
        <property type="nucleotide sequence ID" value="XM_001420829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S618"/>
    <dbReference type="STRING" id="436017.A4S618"/>
    <dbReference type="GeneID" id="5004855"/>
    <dbReference type="Gramene" id="ABO99159">
        <property type="protein sequence ID" value="ABO99159"/>
        <property type="gene ID" value="OSTLU_26958"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26958"/>
    <dbReference type="eggNOG" id="KOG0328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
    <dbReference type="OMA" id="TRFHDFK"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18045">
        <property type="entry name" value="DEADc_EIF4AIII_DDX48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000849">
        <property type="entry name" value="ATP-dependent RNA helicase DBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="62"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="243"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="404" mass="45772" checksum="093CF6B25AF68007" modified="2007-05-15" version="1">MAKDAGKRTATSYDADEKISFETSEGIEPRATFDAMGIREDLLRGLYSYGFEKPSAIQQRAVVPIISGRDVIAQAQSGTGKTSMISLALCQMLDTTSREVQGLVLSPTRELAVQTEKTALSLGNFMNVQVHACIGGRSIGDDIRKLDYGCHIVSGTPGRVFDMIKRRNLRTRGIKILVLDEADEMLNKGFKEQIYDVYRYLPPETQVVLVSATLPNEVLEMTSKFMTDPMRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKKKVDWLTEKMRQNNFTVSAMHGDMPQKEREEIMNEFRGGTTRVLITTDVWARGIDVQQVSLVINYDLPGNRENYIHRIGRSGRYGRKGVAINFVKADDVRALRDIEQYYSTQIDEMPMNVADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6E1</accession>
    <name>A4S6E1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleosome assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_41877</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420927.1">
        <property type="nucleotide sequence ID" value="XM_001420890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6E1"/>
    <dbReference type="STRING" id="436017.A4S6E1"/>
    <dbReference type="GeneID" id="5005133"/>
    <dbReference type="Gramene" id="ABO99220">
        <property type="protein sequence ID" value="ABO99220"/>
        <property type="gene ID" value="OSTLU_41877"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41877"/>
    <dbReference type="eggNOG" id="KOG1507">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038841_4_1_1"/>
    <dbReference type="OMA" id="AAECKQN"/>
    <dbReference type="OrthoDB" id="27325at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.90:FF:000005">
        <property type="entry name" value="Nucleosome assembly protein11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="298"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="41993" checksum="2432F402A715D409" modified="2007-05-15" version="1">MAALQQLHGNSGLIGALQQKLDGLVGLRSGFLEELHPRVRARVKALEKLQEAHDGVHEAYLEEKKALEAKYAALYAPMYKARSEIVTGAKEAAVPDDDEELKAEIEAAAKDAVEAPKGVPEFWMIALKNNEELAQMITERDEGALKHLIDITTSALEGEDEDGDELCGFKIDFHFEENEYFEDSVLTKTYHMDDEEDNLLRYIESSEINWKSGKNLTVKVLRKKPKPGAKNKKPITKTEPAESFFQFFYPPEVPDEEEQQNMSEDDAEQLQDAMEQDYELGMMIANNLIPDAVNWFTGDAFADDEEDEFDEDDDEDEFDDEDDEDDEDDEDDEDEDEDEEEEFVGGKKSFAAPPAMGGAAKEGEQPPECKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6S1</accession>
    <name>A4S6S1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_27219</name>
        <name evidence="12" type="ORF">OSTLU_29690</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421142.1">
        <property type="nucleotide sequence ID" value="XM_001421105.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422813.1">
        <property type="nucleotide sequence ID" value="XM_001422776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6S1"/>
    <dbReference type="STRING" id="436017.A4S6S1"/>
    <dbReference type="GeneID" id="5005200"/>
    <dbReference type="GeneID" id="5006961"/>
    <dbReference type="Gramene" id="ABO99435">
        <property type="protein sequence ID" value="ABO99435"/>
        <property type="gene ID" value="OSTLU_27219"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01172">
        <property type="protein sequence ID" value="ABP01172"/>
        <property type="gene ID" value="OSTLU_29690"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27219"/>
    <dbReference type="KEGG" id="olu:OSTLU_29690"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013173_6_5_1"/>
    <dbReference type="OMA" id="HNFRLEY"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="10">
        <location>
            <begin position="12"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP01172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="384" mass="41754" checksum="68CE45FCB7749CA5" modified="2007-05-15" version="1">MDATRREVASERAYALSARFAARVAWCCQEGCYPHKDHHVNQDACATWEGREMAHEEAVIDGEGNDAVARRETGRVLVGVFDGHGKHGEECAQIARATFAETLARETRGGAALRDGYARTFEAVNAVVCKEMGENASFSGSTAITALFDDEGVVRVGNVGDSRCVVGVERAAGVAVGNRHTRRWEVRDLTHDQTCFRADERARMKAEATSPMTFATIGMVLGETEAHEDFGDGEPGSDEEYCDDPPRVFMAGYRFPGCAFTRSIGDTVGKSLGVSATPEMSEFDLNAEPSTRCVVVASDGVFEFMSSAETMAIAEKFYEENMPGAAERAAHAIVRAAFSRWQEHDERADDITAVVTFIYPLDSDTSTATVVVNDMDDALNKLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S753</accession>
    <name>A4S753_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_18007</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421212.1">
        <property type="nucleotide sequence ID" value="XM_001421175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S753"/>
    <dbReference type="STRING" id="436017.A4S753"/>
    <dbReference type="GeneID" id="5005541"/>
    <dbReference type="Gramene" id="ABO99505">
        <property type="protein sequence ID" value="ABO99505"/>
        <property type="gene ID" value="OSTLU_18007"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18007"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_5_1"/>
    <dbReference type="OMA" id="LTDIMEP"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="507"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="62434" checksum="2FFEA2864C84F68E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S766</accession>
    <name>A4S766_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH HARE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_25476</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421400.1">
        <property type="nucleotide sequence ID" value="XM_001421363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S766"/>
    <dbReference type="STRING" id="436017.A4S766"/>
    <dbReference type="GeneID" id="5005487"/>
    <dbReference type="Gramene" id="ABO99693">
        <property type="protein sequence ID" value="ABO99693"/>
        <property type="gene ID" value="OSTLU_25476"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25476"/>
    <dbReference type="eggNOG" id="ENOG502QQYM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_691501_0_0_1"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Asxl_HARE-HTH"/>
    </dbReference>
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        <property type="entry name" value="RLT1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36968:SF13">
        <property type="entry name" value="HOMEOBOX-DDT DOMAIN PROTEIN RLT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36968">
        <property type="entry name" value="HOMEOBOX-DDT DOMAIN PROTEIN RLT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05066">
        <property type="entry name" value="HARE-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51913">
        <property type="entry name" value="HTH_HARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HTH HARE-type" evidence="3">
        <location>
            <begin position="99"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="399" mass="43718" checksum="3F99EC952E6B53F8" modified="2007-05-15" version="1">MVASTKARRGARGDHEVIDRKEAHAEATTKGGHMSTRNRGDAHVDEDGKRTPDNVLVNTLAKGRAVPTSSSDTDEEAMMVKRAKKNWSADAVALGYEIGTIKHSAYVLLAESGTRGMTVASIVGTAQRLSMYSWGTCKTPNNSVTAALSQDETFVRIAPSTYCLRSQLRGSGNDLPAPRTSSGSHDSGTTGIGHGNGRNGDSGACQSGQGHGRQQKKHRAPQYAPRARSPMHFVVDEPYNSGYDDDEAVNIHVEDSFDRFDRMGDAKRTADALAQESYRRRMDVYGHNVGDEFGTSFHFPPTEIVRPDHSPEAAVAGSCLLYYPTARAAERTGTSRSLRVLRRSLLGCSSSTWRSIIRYSVTISNKGDHTRFQGRDRRRVNILSRPTNVYNKTKQSQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7N9</accession>
    <name>A4S7N9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-rRNA-processing protein TSR2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_93719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TSR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421487.1">
        <property type="nucleotide sequence ID" value="XM_001421450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7N9"/>
    <dbReference type="STRING" id="436017.A4S7N9"/>
    <dbReference type="GeneID" id="5005463"/>
    <dbReference type="Gramene" id="ABO99780">
        <property type="protein sequence ID" value="ABO99780"/>
        <property type="gene ID" value="OSTLU_93719"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93719"/>
    <dbReference type="eggNOG" id="KOG4032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074896_1_0_1"/>
    <dbReference type="OMA" id="LAKDEWF"/>
    <dbReference type="OrthoDB" id="498408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="123"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="23441" checksum="7F062148BD6385C3" modified="2007-05-15" version="1">MLMGRPGGTKMASEHAPTFRRGVKAVFDRWTAMQLAVVNAWGGTESERKAREAEEEIAEWFASRKSKDALELEDLLIEILGDDFNVTCEDGSPGEVAKALWMMYEQCAEGRYDMVAQIESKPLPRESIERSRQIEEDKRWSMNGGGDMDTGASSSDDEGDDEMDAVDADGLAEQLGGAFNVHPSGDDALDTSARRLKNEPDDDGWCTVPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S814</accession>
    <name>A4S814_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_40730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421548.1">
        <property type="nucleotide sequence ID" value="XM_001421511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S814"/>
    <dbReference type="STRING" id="436017.A4S814"/>
    <dbReference type="GeneID" id="5005819"/>
    <dbReference type="Gramene" id="ABO99841">
        <property type="protein sequence ID" value="ABO99841"/>
        <property type="gene ID" value="OSTLU_40730"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40730"/>
    <dbReference type="eggNOG" id="KOG1256">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_45_5_1"/>
    <dbReference type="OMA" id="ETCAYVC"/>
    <dbReference type="OrthoDB" id="494792at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF32">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="15"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="623" mass="67973" checksum="CD2269C17E30D7D9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8F7</accession>
    <name>A4S8F7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GHMP kinase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_89290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421762.1">
        <property type="nucleotide sequence ID" value="XM_001421725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8F7"/>
    <dbReference type="STRING" id="436017.A4S8F7"/>
    <dbReference type="GeneID" id="5005699"/>
    <dbReference type="Gramene" id="ABP00056">
        <property type="protein sequence ID" value="ABP00056"/>
        <property type="gene ID" value="OSTLU_89290"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89290"/>
    <dbReference type="eggNOG" id="KOG0631">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_507552_0_0_1"/>
    <dbReference type="OMA" id="MYQSHAS"/>
    <dbReference type="OrthoDB" id="498899at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF35">
        <property type="entry name" value="L-ARABINOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457">
        <property type="entry name" value="MEVALONATE KINASE/GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="3">
        <location>
            <begin position="123"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="4">
        <location>
            <begin position="396"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="53314" checksum="9EEC97A6C0C40B5B" modified="2007-05-15" version="1">MGGIADYSGATVAQLGLGGRRTECRARFRDAASGTSGTFRARTVTIGTRGAEEEDARCFEARFDEVFDAETFDAGKTREYFERTPSAANERWAAYVAGAMGEFLRAISSDADASNKRARAWVKKLARCDCEIEIRSDVPQGKGVASSAAVEIAVARAVAASALRAGVVSEDDAARRFSAHVAMIPLYCQTAENDVVGAPCGFMDQYACFHSVDSASRGNFIAIDCDLANTSHDGAEDIYRLVPLPRKLRVWGIDSGVRHSNSGGSDYARVRCGTFMGKKILINEMNARLNRDVVPSKVDLCGVITARQWDEGSAGSPMSWSQHVDEEMTGKSFLARYISHDDEPNTTIDADSTYTLRATVSHAVREHARVREFLSILEDWPSDDVCADDDVRQLGRRLGDLMFASHSSYSSVGLGSTATDDLVRLVREVDVERNALFGAKITGGGSGGVVCVLGEDSPSARAAIDAVRREYAKKHSLTNLPDLLHASHVTDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8G0</accession>
    <name>A4S8G0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lumenal PsbP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PSBP4</name>
        <name evidence="3" type="ORF">OSTLU_89292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421763.1">
        <property type="nucleotide sequence ID" value="XM_001421726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8G0"/>
    <dbReference type="STRING" id="436017.A4S8G0"/>
    <dbReference type="GeneID" id="5005651"/>
    <dbReference type="Gramene" id="ABP00057">
        <property type="protein sequence ID" value="ABP00057"/>
        <property type="gene ID" value="OSTLU_89292"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89292"/>
    <dbReference type="eggNOG" id="ENOG502QU0F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039569_1_0_1"/>
    <dbReference type="OMA" id="RMYYQVE"/>
    <dbReference type="OrthoDB" id="2020255at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048564">
        <property type="term" value="P:photosystem I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF15">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="2">
        <location>
            <begin position="77"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="271" mass="29973" checksum="F62D81AB22E873C7" modified="2007-05-15" version="1">MARASSIATHRATPASTPRRAPAIQRAVVARCDARSRSTTTTTTTRRDAMRAALSAVALARVAIATPARAFERPPIGFARYTDAIDGYGFDRPSAWVEVRGSGNDVFFRDASEVETNAFVAVSSPSSSAYESVEDLGTAEDAAKRVLEQYVGELMSTRLGVRREKEILNARRRTKSDGKVYYDVEVRISSYSARNQYGLTAEDRPQTLEWDRTLRSALGTENGKLYELRLQSPTASYEKNSKIFDVMVDSFRQFEADTPSVSSYIGLRIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8G5</accession>
    <name>A4S8G5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27844</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421764.1">
        <property type="nucleotide sequence ID" value="XM_001421727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8G5"/>
    <dbReference type="GeneID" id="5005726"/>
    <dbReference type="Gramene" id="ABP00058">
        <property type="protein sequence ID" value="ABP00058"/>
        <property type="gene ID" value="OSTLU_27844"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27844"/>
    <dbReference type="HOGENOM" id="CLU_770283_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="360" mass="40037" checksum="3CFA1995632CB2DB" modified="2007-05-15" version="1">MSRRATRERSLVASVRAPSDDRARVQATTRETTARLGSLDARPGRATGTPRKRPAATAEGARGTPGQRTEKRAPPATDGRACETCGAEKTSRWRRMDDGGGDATRFRCKACFQRERRKRNATTEHVVDGVVRACVECGETKCRGEWVRVAADDPARGTAATGREGGALGTRCAKCYERARKERRKNEGALTRCEKCGNSANGMLLVSDPSEDAAAGGKCCHKCYHRTKNRMRKLRDERTCADCRKAKRTEPDVRWYRSKETGPEGEPVWTCHQCFSDRANHPDLNAAGAPRKRMPPHKNGGKKAQKPSSAPPRHCPSCDRTKQSSQWRKSGEHTVCTACYQRHLRARKYRQREPVGTFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8L5</accession>
    <name>A4S8L5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lhcb4</name>
        <name evidence="9" type="ORF">OSTLU_27891</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421643.1">
        <property type="nucleotide sequence ID" value="XM_001421606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8L5"/>
    <dbReference type="STRING" id="436017.A4S8L5"/>
    <dbReference type="GeneID" id="5005790"/>
    <dbReference type="Gramene" id="ABO99936">
        <property type="protein sequence ID" value="ABO99936"/>
        <property type="gene ID" value="OSTLU_27891"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27891"/>
    <dbReference type="eggNOG" id="ENOG502QRH9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057943_0_0_1"/>
    <dbReference type="OMA" id="ERPLWYP"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="260" mass="27836" checksum="0F83A89CD86CE4D9" modified="2007-05-15" version="1">MFKTKAPAPKTAVKKSAPAKKAPAKKAPAKKVAAKKAPVRKAGDDELWRPGAVRPAWLDGSLPGDRGFDPFNLSKPIEYVQFDLDALDGSAATNPAGRVIGKLKKTDNKPKARAIVPYDESFDIMRFRECELLHSRWAMLGLVGATAAEAATGISWADAGKVELEQPQYLGFPLPGLSVASLTAIEVLAMGYLEVARSAELDQNKRMYPGGAFDPLGYVANADAEEEFRLKTAELKHGRLAMVGMLIISIEAAAGHGVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Y2</accession>
    <name>A4S8Y2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydroxyproline O-arabinosyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_37760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421970.1">
        <property type="nucleotide sequence ID" value="XM_001421933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Y2"/>
    <dbReference type="STRING" id="436017.A4S8Y2"/>
    <dbReference type="GeneID" id="5006010"/>
    <dbReference type="Gramene" id="ABP00264">
        <property type="protein sequence ID" value="ABP00264"/>
        <property type="gene ID" value="OSTLU_37760"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37760"/>
    <dbReference type="eggNOG" id="ENOG502QQNK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065254_0_0_1"/>
    <dbReference type="OMA" id="AQPPWDK"/>
    <dbReference type="OrthoDB" id="10259977at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF4">
        <property type="entry name" value="HYDROXYPROLINE O-ARABINOSYLTRANSFERASE RDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="7">
        <location>
            <begin position="11"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="318" mass="35969" checksum="403EE7F8A8EF8472" modified="2007-05-15" version="1">MRGDPDPSRKFHVVMTTNNAVYQGWQARVMYYHFQKQKAAQGPNGQMGGFTRVLHDVADGLEDEIPTCIVDRLEDELGFVVLSRPFAFVQFFEKCPQIEEDFILMAEPDHLYIKPVPNLMRGDTPAAFPFFYINPKEKPDIVRRFLPGITDEEMKDIDGIGSSPVFIRKDDLERLAPAWAEMSVALQKDKDAKAAWGWVIEMYGYTLAAYKLGISHDLRPQMAAQPPWDKAVGDFISIHFTYGMDYDLDGVFTPGKIGAWRFDKRSYSHAYPPKKIPDPPKGMNNDLVRALVDAVNEASAALPDWGKWGTENVIAGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Y6</accession>
    <name>A4S8Y6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_93844</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421972.1">
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    <dbReference type="STRING" id="436017.A4S8Y6"/>
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    <dbReference type="Gramene" id="ABP00266">
        <property type="protein sequence ID" value="ABP00266"/>
        <property type="gene ID" value="OSTLU_93844"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93844"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_333841_0_0_1"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Plasminogen Kringle 4"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00130">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57440">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50070">
        <property type="entry name" value="KRINGLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0420">Kringle</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673141" description="Protein kinase domain-containing protein" evidence="10">
        <location>
            <begin position="29"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="12">
        <location>
            <begin position="83"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="515"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="833"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="834"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="549"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50070"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP00266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="856" mass="93837" checksum="162B7638829B81A0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S901</accession>
    <name>A4S901_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_13344</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABP00274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="5005876"/>
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        <property type="protein sequence ID" value="ABP00274"/>
        <property type="gene ID" value="OSTLU_13344"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG0069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_4_1"/>
    <dbReference type="OMA" id="HAYGNVG"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="D-iso_2-hydroxyacid_DH_PdxB"/>
    </dbReference>
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        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
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        <property type="entry name" value="D-isomer_DH_CS"/>
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        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
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    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="22"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="118"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="32450" checksum="EEBBE3BBA61E70AB" modified="2007-05-15" version="1">MALVRKRLDVVVFDDDVARIEHGAVVLVTKEIKVDVERLPKSVRLIAEAGTGTDNIDATAAARRGIAVCNAPEYSTDGVAALVVAYASAAAVGLCERHAALRKGDRRDFNRDFSGLTTFPTMFELRGKTIGLIGGTGSIGRAVARACRALGMRATCHSRSARDEEGLWEAVSLETLLRTSDFVSVHCPLTEETRGMIDADALAMMKPTARLINTARGAVVNERDLIVALREKRIAGAMLDVQENEPPSDDSPLYTLENVYLTPHIGWKRVETRQRLVDMVAANVEAFLRGEPINVISPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S944</accession>
    <name>A4S944_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421870.1">
        <property type="nucleotide sequence ID" value="XM_001421833.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="5006040"/>
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    </dbReference>
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    </dbReference>
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            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="574" mass="64429" checksum="BD3A99211260568A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4S948</accession>
    <name>A4S948_OSTLU</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">OSTLU_93862</name>
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    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4S948"/>
    <dbReference type="GeneID" id="5005901"/>
    <dbReference type="Gramene" id="ABP00296">
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        <property type="gene ID" value="OSTLU_93862"/>
    </dbReference>
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    <dbReference type="OMA" id="HEGYMLE"/>
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    <dbReference type="Proteomes" id="UP000001568">
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    </dbReference>
    <dbReference type="InterPro" id="IPR044200">
        <property type="entry name" value="At5g03900-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380">
        <property type="entry name" value="OS02G0533000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380:SF4">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="506"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="573" mass="63327" checksum="51868C01B228DECA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S961</accession>
    <name>A4S961_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S961"/>
    <dbReference type="STRING" id="436017.A4S961"/>
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    <dbReference type="Gramene" id="ABP00301">
        <property type="protein sequence ID" value="ABP00301"/>
        <property type="gene ID" value="OSTLU_25671"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SBEM">
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    </dbReference>
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    <dbReference type="OMA" id="HCTVFHT"/>
    <dbReference type="OrthoDB" id="119121at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37204">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="37141" checksum="F2F7FEDA2EF0EB19" modified="2007-05-15" version="1">MFDRRTRAIALAALAGAACGAGAYYACASRVFARDDDDDDDDDDDDDYDDDDARTRRAEASTSKKRAPIDVKHTREVSRTYEALELAFATHGLDATTTTARRRFRFARRADVGTRPKTYAEMGMPSDCARLVILTMEDAPAIVSAAERATRELTRLCGTTMDAYAPGRGSLHVTLFHLSRTFEYVRAPVEFASAATLPPNAPNAREDAVAYEESAVAEALRGCGECELEVDRVCLAPSGCLILCFNDVHGNVQTIRERLARSAVGAARAQNDTVHCTLARLFARADGFQMDPERARAVQAMCATVTSALRGARFKARSATYCVERTFSHCDGRRARISLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S974</accession>
    <name>A4S974_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fcf2 pre-rRNA processing C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_7983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421886.1">
        <property type="nucleotide sequence ID" value="XM_001421849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S974"/>
    <dbReference type="STRING" id="436017.A4S974"/>
    <dbReference type="GeneID" id="5006054"/>
    <dbReference type="Gramene" id="ABP00180">
        <property type="protein sequence ID" value="ABP00180"/>
        <property type="gene ID" value="OSTLU_7983"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7983"/>
    <dbReference type="eggNOG" id="KOG3100">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075129_4_0_1"/>
    <dbReference type="OMA" id="WKNKGRQ"/>
    <dbReference type="OrthoDB" id="427886at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="3">
        <location>
            <begin position="21"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="15608" checksum="EA34FAB23C1A35AF" modified="2007-05-15" version="1" fragment="single">GLFVAPNDKTKVRRELRKMERKTAGKGWFDMKAVEYTPELRREMRMLKLRGAYDPKRFYKNADTSRLPTHFQVGTVVGGAADFYSARLAKKDQKRTLAEEIMHDKDIEHVRRHRFAKIQEKNAGNMGRKAKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9I5</accession>
    <name>A4S9I5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thioredoxin peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thioredoxin-dependent peroxiredoxin Q</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_28213</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422072.1">
        <property type="nucleotide sequence ID" value="XM_001422035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9I5"/>
    <dbReference type="STRING" id="436017.A4S9I5"/>
    <dbReference type="GeneID" id="5006235"/>
    <dbReference type="Gramene" id="ABP00389">
        <property type="protein sequence ID" value="ABP00389"/>
        <property type="gene ID" value="OSTLU_28213"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28213"/>
    <dbReference type="eggNOG" id="KOG0855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_14_1_1"/>
    <dbReference type="OMA" id="PKKFMGK"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF4">
        <property type="entry name" value="AHPC_TSA FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="23"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="181" mass="19318" checksum="4956217D95C3648C" modified="2007-05-15" version="1">MLLASAFAASTTLGGAQNALAAVDVGSKAPEFTLPGTAGDSVTLSDALKANDYVVLYFYNQDGSPGCSIEAQRFESAIPQFTAKKARVLGVSMDSLEKHEEFCDSKGLKSFTLLSDNDGRVSEAYGADLKIPIFGRFSDRQTFLIKNDGTIVNHWLERDSSMASVKTTAHVDQILAAIEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9T9</accession>
    <name>A4S9T9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422124.1">
        <property type="nucleotide sequence ID" value="XM_001422087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9T9"/>
    <dbReference type="GeneID" id="5006287"/>
    <dbReference type="Gramene" id="ABP00441">
        <property type="protein sequence ID" value="ABP00441"/>
        <property type="gene ID" value="OSTLU_18700"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18700"/>
    <dbReference type="HOGENOM" id="CLU_1477465_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="19168" checksum="E5B56FE40506D1D8" modified="2007-05-15" version="1">MDAVSEIASSSALAGALAGPLGIARGTEATAATETTAASARANEGADADDADDADDADDAGTRALESQGRIVSLLASFERGTPMMALFLMIFFYKHFAQLAFVGWLTYALLRANGRTVTEVAKREARKVADVGAVMVALLAHLLVVWTMTPTGRRARGMFQEPAGFWTCAFDVAALDLCASAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA06</accession>
    <name>A4SA06_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422158.1">
        <property type="nucleotide sequence ID" value="XM_001422121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA06"/>
    <dbReference type="GeneID" id="5006320"/>
    <dbReference type="Gramene" id="ABP00475">
        <property type="protein sequence ID" value="ABP00475"/>
        <property type="gene ID" value="OSTLU_25752"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25752"/>
    <dbReference type="HOGENOM" id="CLU_1498716_0_0_1"/>
    <dbReference type="OrthoDB" id="568118at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="180" mass="18786" checksum="E0E79186D1A3D09D" modified="2007-05-15" version="1">MAATAATTTTSMNATSARSSARATRARRADKTTARARRRADDGDDDGRAATTTTRAACAAIAAMAMACSSARAYVPGFFAASAEASETTTTTFAGRYADPKHPGCLREISADGTVRGEDGDPGCGKTTRTRPWTLSGVIDVNDDSIFIDFSPKGGPANLLGERVEGGVKFPDGNVWRKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA13</accession>
    <name>A4SA13_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422267.1">
        <property type="nucleotide sequence ID" value="XM_001422230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA13"/>
    <dbReference type="GeneID" id="5006219"/>
    <dbReference type="Gramene" id="ABP00584">
        <property type="protein sequence ID" value="ABP00584"/>
        <property type="gene ID" value="OSTLU_18759"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18759"/>
    <dbReference type="HOGENOM" id="CLU_1071145_0_0_1"/>
    <dbReference type="OMA" id="WASMELK"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019341">
        <property type="entry name" value="Alpha/Gamma-adaptin-bd_p34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659:SF1">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="260" mass="28329" checksum="631D0DE7E84FE6F9" modified="2007-05-15" version="1">MAYVDAVRATLGARDDDDDDDDDDGRWTLDTKYYVADVRARVVDDATAGEKRESASRARRGRARAVVLACGSAEEFARGRDALERDARDDEDATEAFEGVDARIVAYDVSEARETGVPEDVRAWALDRMFEVVEVRLDDAAADEALTRDAAKDEDAHGVRRTIAALEATMWDVLELKSLGEESDLGREMRATTTTRTREDVEALAVANGLLGDDAAESPSAMGEGVVQARIAALYDDALALKEEERLEKLADILAGDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA32</accession>
    <name>A4SA32_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_41981</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422172.1">
        <property type="nucleotide sequence ID" value="XM_001422135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA32"/>
    <dbReference type="STRING" id="436017.A4SA32"/>
    <dbReference type="GeneID" id="5006230"/>
    <dbReference type="Gramene" id="ABP00489">
        <property type="protein sequence ID" value="ABP00489"/>
        <property type="gene ID" value="OSTLU_41981"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41981"/>
    <dbReference type="eggNOG" id="KOG0048">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028567_26_4_1"/>
    <dbReference type="OMA" id="HGNKWTE"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF76">
        <property type="entry name" value="TRANSCRIPTION FACTOR MYB124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="1">
        <location>
            <begin position="46"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="54"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="99" mass="11343" checksum="BDDE4795BF580B37" modified="2007-05-15" version="1" fragment="single">MWTSDEDEKLLALIEKHGARRWNSLASAMETKTAKQCRRRWSGHLTTEIKEHEWTEAEDLALLDAHEKLGNKWTAIAKLVGGRTDNGAKNRFKALVDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA80</accession>
    <name>A4SA80_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_28464</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-catenin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422297.1">
        <property type="nucleotide sequence ID" value="XM_001422260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA80"/>
    <dbReference type="GeneID" id="5006378"/>
    <dbReference type="Gramene" id="ABP00614">
        <property type="protein sequence ID" value="ABP00614"/>
        <property type="gene ID" value="OSTLU_28464"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28464"/>
    <dbReference type="HOGENOM" id="CLU_954408_0_0_1"/>
    <dbReference type="OrthoDB" id="449062at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056597">
        <property type="entry name" value="ARM_LRRK2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23744">
        <property type="entry name" value="ARM_LRRK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671955" description="Vacuolar protein 8" evidence="8">
        <location>
            <begin position="24"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="LRRK2 ARM repeat" evidence="9">
        <location>
            <begin position="64"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="292" mass="32565" checksum="00DA907D78FB415D" modified="2007-05-15" version="1">MAKVKIMLILSMVLILRMPSALAGALTHALLRVGGPRVRQAVEKGMKQGIMDSFPGGVQDLLAYLHRHREDEIKQEFGCMALMIMCRENTENRRIAGEQGAIQAVVNALNRHRENKEVQRDGHMALVIMCEDNTENRRIAGEQGAIQAVVDALNRHRGNREVQRDGQLALAIMCKDNTENRRIAGEQGAIQTVVDALNRHRGNREVQRDGQLALAIMCKDNTENRRIAGEQGAIQTVVDALNRHRGNKEVQANGHMALASMCINNTENRRIVDAYGQTVSYSPQPPFARPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAB4</accession>
    <name>A4SAB4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_18839</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422311.1">
        <property type="nucleotide sequence ID" value="XM_001422274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAB4"/>
    <dbReference type="STRING" id="436017.A4SAB4"/>
    <dbReference type="GeneID" id="5006413"/>
    <dbReference type="Gramene" id="ABP00628">
        <property type="protein sequence ID" value="ABP00628"/>
        <property type="gene ID" value="OSTLU_18839"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18839"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_2_1"/>
    <dbReference type="OMA" id="WYLGYYK"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43574">
        <property type="entry name" value="EPIMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01713">
        <property type="entry name" value="NUCEPIMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="345" mass="37855" checksum="9724EE65A1095B71" modified="2007-05-15" version="1">METYLVTGAAGFIGSYVARALNERRVRVVGLDNINGYYPRALKRNRISKLAEVGVHVVEADLNDSLTLRGILDTCRVTTIVHLAAQAGVRYAVKNPGSYVHSNVAGFVSLLEEVVKTSPIPRVIFASSSSVYGLNTKLPFSESDVTDSPASLYAATKKANELLARTYNHIHGVALTALRFFTVYGPHGRPDMAYYSFANNIRAGQLVNIFRSADGSELARDFTYIDDIVRGIIAACDTSEASGKKADGSNPPFRVYNLGNTHPVTVSDFVSKLEHALGMVAKRNYLPMPKTGDVPYTHANISAAERDLSYKPRVDLDTGLQYFAEWYLGYYDSGANSEDFKYIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAF1</accession>
    <name>A4SAF1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422425.1">
        <property type="nucleotide sequence ID" value="XM_001422388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAF1"/>
    <dbReference type="GeneID" id="5006433"/>
    <dbReference type="Gramene" id="ABP00742">
        <property type="protein sequence ID" value="ABP00742"/>
        <property type="gene ID" value="OSTLU_94013"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94013"/>
    <dbReference type="eggNOG" id="ENOG502R2ZH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1257909_0_0_1"/>
    <dbReference type="OMA" id="VFTACWN"/>
    <dbReference type="OrthoDB" id="3700at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34118:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34118">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="220" mass="23815" checksum="70A8A2300C00F1DE" modified="2007-05-15" version="1">MRSSSTSRSTRTDARALGRAARAPNANRRNPRRGNIATPRRATPADALDEKRMSDEEYVALKRELSSTTLAHGAALSAYCLLGYGVAPGLSAALGSAGALGYLRLLQDYVDGVSESLENGNVSEADYTRNLVYEPVTDVGAMLSGAFGKVGGVYSRALLQRRLLVPTALVVFTACWNRLDLPFDFSYGATFCGFLCYKTAVLAKTWDILKPLLLEAPRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAR7</accession>
    <name>A4SAR7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422482.1">
        <property type="nucleotide sequence ID" value="XM_001422445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAR7"/>
    <dbReference type="STRING" id="436017.A4SAR7"/>
    <dbReference type="GeneID" id="5006712"/>
    <dbReference type="Gramene" id="ABP00799">
        <property type="protein sequence ID" value="ABP00799"/>
        <property type="gene ID" value="OSTLU_29356"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29356"/>
    <dbReference type="eggNOG" id="KOG0894">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041481_1_3_1"/>
    <dbReference type="OMA" id="FTNYHPE"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="7"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="174" mass="19343" checksum="09CAE136C8ABC158" modified="2007-05-15" version="1">MAPPSKACATRLTRELRQFRAAPPPLAPRVHVDDGDLLEWFVLIQGAHDTPYERGWYVMKIKFKPTYPFAAPAVSVLTPNGRFAENQSICMSMTEWHQESWNPAWSSQAIVTGFISFMSANEHTSGGVRTTDEEKKRLAAASLAWNAAQPGLVKKFPELADAEAMKALETAKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAT8</accession>
    <name>A4SAT8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422495.1">
        <property type="nucleotide sequence ID" value="XM_001422458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAT8"/>
    <dbReference type="GeneID" id="5006720"/>
    <dbReference type="Gramene" id="ABP00812">
        <property type="protein sequence ID" value="ABP00812"/>
        <property type="gene ID" value="OSTLU_94061"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94061"/>
    <dbReference type="HOGENOM" id="CLU_392017_0_0_1"/>
    <dbReference type="OrthoDB" id="10601353at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="704" mass="76547" checksum="DBBE64E36F611244" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAV7</accession>
    <name>A4SAV7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422670.1">
        <property type="nucleotide sequence ID" value="XM_001422633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAV7"/>
    <dbReference type="STRING" id="436017.A4SAV7"/>
    <dbReference type="GeneID" id="5006727"/>
    <dbReference type="Gramene" id="ABP00987">
        <property type="protein sequence ID" value="ABP00987"/>
        <property type="gene ID" value="OSTLU_29394"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29394"/>
    <dbReference type="eggNOG" id="KOG0603">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_714450_0_0_1"/>
    <dbReference type="OMA" id="DIMITSM"/>
    <dbReference type="OrthoDB" id="1675360at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="368" mass="41250" checksum="C0EE04E0624129A9" modified="2007-05-15" version="1">MGCAQGTLKRAGSVKARDRSLAVMKSLFPVAFVDAYEVESKATFDAYGGAFDVVSREDGSARTAVLARLKKQADGESLTISQFSMEEYVLQLLRHDGVASVYESFTELRKRPAMGVLIVDRLRGAKLIDYLQQKDGAKLGEDEAREIMVQLASVLKHLVDCGVTCGNLDLDTLVFREEDNMELVVTSMRYASLAGHPSPYVVEYGTYEIEDELGQPVTRTFPEDARKLHFAAPERLKPDSRGRDRQPSVDVWSFGVIMYTLLAGYLPFEGEDSRTLCEKIRQGNFTAFKYDVETWDSISMGAKDLIAGCLRVDPRRRFNIERIMKHPWIRKFEDPNATFIALGSDLGTPPLSYVSNSSDYDDLHSPMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAZ5</accession>
    <name>A4SAZ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_25853</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the p23/wos2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422688.1">
        <property type="nucleotide sequence ID" value="XM_001422651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAZ5"/>
    <dbReference type="STRING" id="436017.A4SAZ5"/>
    <dbReference type="GeneID" id="5006585"/>
    <dbReference type="Gramene" id="ABP01005">
        <property type="protein sequence ID" value="ABP01005"/>
        <property type="gene ID" value="OSTLU_25853"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25853"/>
    <dbReference type="eggNOG" id="ENOG502S6JT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_519178_0_0_1"/>
    <dbReference type="OMA" id="TWTYGAW"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="15"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="525" mass="57865" checksum="3B7EE4C3C397592E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB42</accession>
    <name>A4SB42_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">COMM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422712.1">
        <property type="nucleotide sequence ID" value="XM_001422675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB42"/>
    <dbReference type="GeneID" id="5006608"/>
    <dbReference type="Gramene" id="ABP01029">
        <property type="protein sequence ID" value="ABP01029"/>
        <property type="gene ID" value="OSTLU_29479"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29479"/>
    <dbReference type="HOGENOM" id="CLU_1996456_0_0_1"/>
    <dbReference type="OrthoDB" id="10257479at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017920">
        <property type="entry name" value="COMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037354">
        <property type="entry name" value="Commd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15857">
        <property type="entry name" value="COMM DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15857:SF0">
        <property type="entry name" value="COMM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51269">
        <property type="entry name" value="COMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COMM" evidence="1">
        <location>
            <begin position="42"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="125" mass="13631" checksum="0AC136E7D4769C59" modified="2007-05-15" version="1">MRGFGFDDAKAETLTRRYAEEALRGERGAATRRGTATNRSDAYDGLEWRLDANVSSRASLVESEAKYLLKLGLARGDDGGTKKTTLAETDYQTLKALKDACESALAASTGAHATRLARYVRRPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBG9</accession>
    <name>A4SBG9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">isopentenyl-diphosphate Delta-isomerase</fullName>
            <ecNumber evidence="5">5.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_13493</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422616.1">
        <property type="nucleotide sequence ID" value="XM_001422579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBG9"/>
    <dbReference type="STRING" id="436017.A4SBG9"/>
    <dbReference type="GeneID" id="5006674"/>
    <dbReference type="Gramene" id="ABP00933">
        <property type="protein sequence ID" value="ABP00933"/>
        <property type="gene ID" value="OSTLU_13493"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13493"/>
    <dbReference type="eggNOG" id="KOG0142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060552_0_1_1"/>
    <dbReference type="OMA" id="GEHEICY"/>
    <dbReference type="OrthoDB" id="510307at2759"/>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02885">
        <property type="entry name" value="NUDIX_IPP_Isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000012">
        <property type="entry name" value="Isopentenyl-diphosphate Delta-isomerase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02150">
        <property type="entry name" value="IPP_isom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF0">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018427">
        <property type="entry name" value="Isopntndiph_ism"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0752">Steroid biosynthesis</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="13">
        <location>
            <begin position="56"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABP00933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="28608" checksum="1BAB6F2FF08C1508" modified="2007-05-15" version="1">MGNRSSSTWDATQTQEDFMRNDRVIVVSAADDVLGSETKENAHKFIEGSSTTPRGTLHRAFSVFLFDDSGRLLLQQRAANKITFPSVWTNTCCSHQLTGQKPDEMDDASAIASGACDGAKRAATRKLKHELGIDAKDVPTESIKFLTRLHYCAADEFAENANQPVGGTWGEHEMDYILFAKIARAGESLPMAVNAEEIDDTKWVTASELKAMMDQSSGLRWSPWFRIIAEKFLYAWWTDLDSLDKHVDVETIHKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBH2</accession>
    <name>A4SBH2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Actin-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ARP3504</name>
        <name evidence="8" type="ORF">OSTLU_29609</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422774.1">
        <property type="nucleotide sequence ID" value="XM_001422737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBH2"/>
    <dbReference type="STRING" id="436017.A4SBH2"/>
    <dbReference type="GeneID" id="5006676"/>
    <dbReference type="Gramene" id="ABP01091">
        <property type="protein sequence ID" value="ABP01091"/>
        <property type="gene ID" value="OSTLU_29609"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29609"/>
    <dbReference type="eggNOG" id="KOG0677">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_0_2_1"/>
    <dbReference type="OMA" id="WEDMQHL"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009825">
        <property type="term" value="P:multidimensional cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010090">
        <property type="term" value="P:trichome morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000007">
        <property type="entry name" value="Actin like 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000148">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP01091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="45865" checksum="C840D658499EFB83" modified="2007-05-15" version="1">MTDASGALPARFATSVGLTNRENVVVCDTGTGFVKAGYAGDEEPRTLFPCMVGRPTLRYEEDAFDDEAMKDVYVGDEAARKRANLEISYPVSNGVVRDWEDMGLVWDRAFESLGCDTRECKVMLTDPPLNPKSNRERMMSTMFETYGFRGAYVQVQAVLTLYAQGLMTGVVVDSGDGVTHVVPVVDGYSFPHLTKRLNVAGRHVTTRMIDLLTRRGYPLNRTSDVETARLIKEELCYVAYDYKRDLQLARETTATNASYTLPDGRVIKFGPERFMGPECLFQPDLIDVESDGISDLVFKCIQENEIDNRRSLYQHIVLSGGNSMYAGLPSRLERDIKRLYLKNVLNGDKEAMKKFKMKVEAPAHRKHMVFVGGAVLADIMRSKDEFWISKQEYEEQGIERALKKCGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQR2</accession>
    <name>A4RQR2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_12087</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415431.1">
        <property type="nucleotide sequence ID" value="XM_001415394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQR2"/>
    <dbReference type="STRING" id="436017.A4RQR2"/>
    <dbReference type="GeneID" id="4999648"/>
    <dbReference type="Gramene" id="ABO93723">
        <property type="protein sequence ID" value="ABO93723"/>
        <property type="gene ID" value="OSTLU_12087"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12087"/>
    <dbReference type="eggNOG" id="ENOG502QSIE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029101_1_1_1"/>
    <dbReference type="OMA" id="GTIKWAM"/>
    <dbReference type="OrthoDB" id="496065at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000014">
        <property type="entry name" value="Probable dual-specificity RNA methyltransferase RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="23S RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544:SF5">
        <property type="entry name" value="RADICAL SAM CORE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01062">
        <property type="entry name" value="methyltransferase_(Class_A)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="84"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO93723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="37062" checksum="B728E90FB149A680" modified="2007-05-15" version="1">MPAFRGKQIADHLYAPNGASARSVDDFTTLSKKLREELKSANVRVGRSRRHHVAAASDGTAKLLLRLDDDRVVETVGIPATENGKNRLTACVSSQVGCPMRCTFCATGKGGFARNLAPHEIVDQVLALEEYFGQRVSNVVFMGMGEPLLNVPNVLKAHEALNKEIGIGARHITISTVGVRGSIEKLAHAQLQSVLAVSLHAPNQELRETIIPSAKVYPMEDLLQDCEQYFVATGRRVTFEYTLLGGINDQPEHAKELGRLLYARNLASHVNLIPYNPVDDSDYQRPSRATVYAFRDILEGLNVPASIRQTRGLEAAAACGQLRNAFQKNAIVGDLAPATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR33</accession>
    <name>A4RR33_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_13743</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415831.1">
        <property type="nucleotide sequence ID" value="XM_001415794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR33"/>
    <dbReference type="STRING" id="436017.A4RR33"/>
    <dbReference type="GeneID" id="4999966"/>
    <dbReference type="Gramene" id="ABO94123">
        <property type="protein sequence ID" value="ABO94123"/>
        <property type="gene ID" value="OSTLU_13743"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13743"/>
    <dbReference type="eggNOG" id="KOG0136">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014629_3_1_1"/>
    <dbReference type="OMA" id="AHAQYMV"/>
    <dbReference type="OrthoDB" id="538336at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000015">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000005">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000013">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="15">
        <location>
            <begin position="50"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="14">
        <location>
            <begin position="170"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="16">
        <location>
            <begin position="309"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="13">
        <location>
            <begin position="510"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO94123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="695" mass="77916" checksum="7FE1545310C48CE7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR86</accession>
    <name>A4RR86_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA/rRNA methyltransferase SpoU type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_28928</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415819.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RR86"/>
    <dbReference type="GeneID" id="4999650"/>
    <dbReference type="Gramene" id="ABO94148">
        <property type="protein sequence ID" value="ABO94148"/>
        <property type="gene ID" value="OSTLU_28928"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28928"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OMA" id="YQHVRHH"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="SpoU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051259">
        <property type="entry name" value="rRNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191:SF7">
        <property type="entry name" value="OBP33PEP LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="159"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="22749" checksum="FF767585CB6C29A8" modified="2007-05-15" version="1">MYFLAHNVAKKHNIGTMARCCTAFGVKSLVLIGSRQFNTFGSHGADGHVHFEHFDSLEEAREKLKGERGCTQILGVEIVDDARAIESHPFTGNTAFIMGNEGHGMTEAQKAICDGFVYIPQYGPGTASLNVSVAASIVMHHFASWAGYEERSREGEKFIVAERPQRTRKRGEVGESPEQVRARRAAARALDKEQETRGEDAIADADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRV7</accession>
    <name>A4RRV7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_2326</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415635.1">
        <property type="nucleotide sequence ID" value="XM_001415598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRV7"/>
    <dbReference type="STRING" id="436017.A4RRV7"/>
    <dbReference type="GeneID" id="4999564"/>
    <dbReference type="Gramene" id="ABO93927">
        <property type="protein sequence ID" value="ABO93927"/>
        <property type="gene ID" value="OSTLU_2326"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2326"/>
    <dbReference type="eggNOG" id="KOG0284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_77_0_1"/>
    <dbReference type="OMA" id="HHWDVKS"/>
    <dbReference type="OrthoDB" id="16717at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045245">
        <property type="entry name" value="Pfs2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836:SF0">
        <property type="entry name" value="PRE-MRNA 3' END PROCESSING PROTEIN WDR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="234"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="321"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="363" mass="40512" checksum="B4CAB9EED8D8B18B" modified="2007-05-15" version="1" fragment="single">RKAVQRRTVDYTATTVRYVEERVYAKDPWNSSHPRPLPGALLDFMPPVAYPHLPATSFATKFVHVSSNKIRTSVNKVMFMPDGRRLLTCSQNGEFTLWNGMSFNFETILQAHNGPIRCAEFSNNDNWLLTGDDEGNVKYFQTTFNNLRSFQVHKEPVTSISFARSDLKFATGSDDASVKIVDFARAETEHTLSGHSGDVKTVEWHPYLGLVASGGKDGALKMWDPKSGHCATTLYGHKNAITCSKWNKNGNWLVTGSKDQTLKVWDLRMLKEIGTYRGHGKDVTEVVWHPTHEAMFTSGAFDGSINYWLVGAGEAPHAEIKGGHEASILSLAWHPAGHILVSGSQDNTTKFWCRNRPGEVARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSA7</accession>
    <name>A4RSA7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3">4.6.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Cnx3</name>
        <name evidence="7" type="ORF">OSTLU_119780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416524.1">
        <property type="nucleotide sequence ID" value="XM_001416487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSA7"/>
    <dbReference type="STRING" id="436017.A4RSA7"/>
    <dbReference type="GeneID" id="5000390"/>
    <dbReference type="Gramene" id="ABO94817">
        <property type="protein sequence ID" value="ABO94817"/>
        <property type="gene ID" value="OSTLU_119780"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119780"/>
    <dbReference type="eggNOG" id="KOG2876">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074693_1_1_1"/>
    <dbReference type="OMA" id="IWDMVKS"/>
    <dbReference type="OrthoDB" id="429626at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="entry name" value="Molybdopterin cofactor biosynthesis C (MoaC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047594">
        <property type="entry name" value="MoaC_bact/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006870">
        <property type="entry name" value="PRK09364.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="Molybdenum cofactor biosynthesis protein C, MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin cofactor biosynthesis C (MoaC)" evidence="6">
        <location>
            <begin position="82"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="228" mass="23769" checksum="9853F6BA56390417" modified="2007-05-15" version="1">MTTLRRLIARTARSVTSMRTRASLSASSFHANGDRASAVEEANASLDETFGLGGVRVGGGGDDAAPTGRLTHVDERSGAASMVNVGSKPSTSREATASARVWLGAEAFALVRENRMKKGDVLATARIAGIMGAKKTHDLIPLCHAIAIDAVKVDLTLNESERAVDIVAVASCTGKTGVEMEALTAAAVSGLTIYDMCKAVSKDIVIGDVRLEAKVGGKSGNWSRREIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSB6</accession>
    <name>A4RSB6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Possible psaO, PSI-O, photosystem I polypeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">psaO</name>
        <name evidence="2" type="ORF">OSTLU_14386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416278.1">
        <property type="nucleotide sequence ID" value="XM_001416241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSB6"/>
    <dbReference type="STRING" id="436017.A4RSB6"/>
    <dbReference type="GeneID" id="5000401"/>
    <dbReference type="Gramene" id="ABO94571">
        <property type="protein sequence ID" value="ABO94571"/>
        <property type="gene ID" value="OSTLU_14386"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14386"/>
    <dbReference type="eggNOG" id="ENOG502S09E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151524_0_0_1"/>
    <dbReference type="OMA" id="WHFGLFL"/>
    <dbReference type="OrthoDB" id="495711at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017498">
        <property type="entry name" value="PSI_PsaO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36311">
        <property type="entry name" value="PHOTOSYSTEM I SUBUNIT O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36311:SF1">
        <property type="entry name" value="PHOTOSYSTEM I SUBUNIT O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22832">
        <property type="entry name" value="PsaO_TMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="135" mass="14853" checksum="19BF1CD5C437839F" modified="2007-05-15" version="1">MVALALTQITVARRSALSRDVRGRKTVKARAAVKVAASSDLKFDDDWKKSSVPVHLASLFGWVVPSASPCPAFENNASLFQVFSDRIGANLANFPQGPAADDKIWLYMLTWHMGLFACMMFGQIGVQARKQGYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSD5</accession>
    <name>A4RSD5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="4 11">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_30288</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416265.1">
        <property type="nucleotide sequence ID" value="XM_001416228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSD5"/>
    <dbReference type="STRING" id="436017.A4RSD5"/>
    <dbReference type="GeneID" id="5000494"/>
    <dbReference type="Gramene" id="ABO94558">
        <property type="protein sequence ID" value="ABO94558"/>
        <property type="gene ID" value="OSTLU_30288"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30288"/>
    <dbReference type="eggNOG" id="KOG1367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_648455_0_0_1"/>
    <dbReference type="OMA" id="NTRWFQG"/>
    <dbReference type="OrthoDB" id="1854730at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="entry name" value="Phosphoglycerate kinase, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406:SF23">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="464" mass="50039" checksum="BB88BCAEDAF6FA9A" modified="2007-05-15" version="1">MPRVRALADARDLTNKIVLVRVDHNCVKRGVVRDVHRIEQSLPTLYNIVERGGRPILMTHVNRPRSAKTGEIARDDDEDGVAAIVDVLRMKLGVTFAAPSFRSDGARGIRSVDTSVNFLLDDLRARRIGGIYLPNTRWFEGEEAGEGTEAYEALARQLAGLADVYVNDAFGSWQAHASTVGITKYLPSYAGLLMQKELRAVEAVLNPKRPFVAVVAGAKVDTKLGTLKAVAARCDSLILGGVVYNAYLCAKYDIEVEGVSEGDVELARELLSPEAQAKIIELPVVVESTSLKGCGCIPKEGECGDPKETLGATRALRVSDLQRGASYGYFLDVAASSFEDEKVKNALHGAKCIFVNAVMGFTSSGFHEGTTALDHAIAANKGARKYFGGGDTIQEFKSLTPALYLSAAVDPTFYLFTGGGTVLRALELGGAEKLETVQCLMADDDEEIEPHAEPKCMRFADCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSE8</accession>
    <name>A4RSE8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_36236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416261.1">
        <property type="nucleotide sequence ID" value="XM_001416224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSE8"/>
    <dbReference type="STRING" id="436017.A4RSE8"/>
    <dbReference type="GeneID" id="5000550"/>
    <dbReference type="Gramene" id="ABO94554">
        <property type="protein sequence ID" value="ABO94554"/>
        <property type="gene ID" value="OSTLU_36236"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36236"/>
    <dbReference type="eggNOG" id="KOG2071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152308_0_0_1"/>
    <dbReference type="OMA" id="ICSHIME"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16982">
        <property type="entry name" value="CID_Pcf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045154">
        <property type="entry name" value="PCF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047415">
        <property type="entry name" value="Pcf11_CID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921:SF3">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="135" mass="14735" checksum="EBFEDCAA2E01734E" modified="2007-05-15" version="1" fragment="single">MSGEEFEEYASALSELVINSKPIITSLTILAGEIAGNDEARAEAIAELIRGHIRTAPAKTKLCGFYLLDSVVKNLRGPFVRCFATGLSDLFLPAYAKVDITQKKSMARLFNTWRPVFPASVLDEIEPHIAPRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT58</accession>
    <name>A4RT58_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_36156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416134.1">
        <property type="nucleotide sequence ID" value="XM_001416097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT58"/>
    <dbReference type="STRING" id="436017.A4RT58"/>
    <dbReference type="GeneID" id="5000252"/>
    <dbReference type="Gramene" id="ABO94426">
        <property type="protein sequence ID" value="ABO94426"/>
        <property type="gene ID" value="OSTLU_36156"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36156"/>
    <dbReference type="eggNOG" id="KOG1236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_6_1_1"/>
    <dbReference type="OrthoDB" id="1290869at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671945" description="Protein kinase domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="75"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="426" mass="47069" checksum="CB1AE711C14D2656" modified="2007-05-15" version="1">MRKRAWATMHSAIALCGAAFIKWAQWASTREDVFPKDLCHQLEQLHDDAPQHSYGQTLRILANEFGFDPRLVFAQFPRKPMASGSVAQVYKARLRKEVAAVCSALAQPRKLDLNEDGTMDVAVKVRHPNVAKRIFLDFQILRAIAGIADALPALKGMQLKNTLGQFSHTMTAQTDLRNEADHLLKFTHNMKSEVQIRAPRPVPGFVTEAVLVETFVKGDGLGSAIKHKTSRNSELCSLGVHAYLLMLLRDNFIHQDLHPGNILYSVENGQSSVDSETAGIVKLELIDFGIADELPKAVRNKFLGFLCFLLRGEGEKAADVALTWDAKQTCTDRVALRRDMARLVSSQGDVYTQRVDLDGLLKEIMQLFRKHGVSIDGIYASLVVSLCVLVGFATSLDPEINLFEVAAPSVMAFALTGDVVGRLFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT62</accession>
    <name>A4RT62_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416369.1">
        <property type="nucleotide sequence ID" value="XM_001416332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT62"/>
    <dbReference type="STRING" id="436017.A4RT62"/>
    <dbReference type="GeneID" id="5000149"/>
    <dbReference type="Gramene" id="ABO94662">
        <property type="protein sequence ID" value="ABO94662"/>
        <property type="gene ID" value="OSTLU_29985"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29985"/>
    <dbReference type="eggNOG" id="KOG3772">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_732347_0_0_1"/>
    <dbReference type="OrthoDB" id="514271at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000086">
        <property type="term" value="P:G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110032">
        <property type="term" value="P:positive regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF17">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="203"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="378" mass="40636" checksum="96490FED5231C846" modified="2007-05-15" version="1">MDAEAKRRRVTAEASLASPPTVRAPAGAFETPARGKTDGEARDGGASGASTATPLPTKRKARAGETGEGMVFAAMPTFARALRDASNANGADWARAEDARAATPCRGGRPLASPPPMKASTSPPAPPRKQALSYGMSYGYTPSRGDTRYDASERVDCEEPATPALAGPCAMIPSALDAALGLPMIDGAALRALLANHESGGAGGPEVVAIDCRFPFEYAGGRVRSALNLYSPTDVQKFLASRATTSANVVYVFYCEFSSERAPRMWRHVRNLDRRDHMATYPALSFPHTYVLQGGYKHFYESFPECCEGGFVSMSDTRYTDACREFTSQSREVWFVAQRAKSMTHAPSPSDEALFRSAERFRGAVRGRGIDFTGMDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTD0</accession>
    <name>A4RTD0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Diflavin flavoprotein A 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Dfa1</name>
        <name evidence="10" type="ORF">OSTLU_119390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mediates electron transfer from NADH to oxygen, reducing it to water. This modular protein has 3 redox cofactors, in other organisms the same activity requires 2 or 3 proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the flavodoxin reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416098.1">
        <property type="nucleotide sequence ID" value="XM_001416061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTD0"/>
    <dbReference type="STRING" id="436017.A4RTD0"/>
    <dbReference type="GeneID" id="5000314"/>
    <dbReference type="Gramene" id="ABO94390">
        <property type="protein sequence ID" value="ABO94390"/>
        <property type="gene ID" value="OSTLU_119390"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119390"/>
    <dbReference type="eggNOG" id="ENOG502RX7H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017490_2_1_1"/>
    <dbReference type="OMA" id="FGMHYCD"/>
    <dbReference type="OrthoDB" id="432169at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07709">
        <property type="entry name" value="flavodiiron_proteins_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051285">
        <property type="entry name" value="NADH_oxidoreductase_modular"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045761">
        <property type="entry name" value="ODP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32145">
        <property type="entry name" value="DIFLAVIN FLAVOPROTEIN A 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32145:SF11">
        <property type="entry name" value="DIFLAVIN FLAVOPROTEIN A 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19583">
        <property type="entry name" value="ODP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="9">
        <location>
            <begin position="331"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="638" mass="70188" checksum="F87C3959265BE9E1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTG9</accession>
    <name>A4RTG9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_48780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416318.1">
        <property type="nucleotide sequence ID" value="XM_001416281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTG9"/>
    <dbReference type="STRING" id="436017.A4RTG9"/>
    <dbReference type="GeneID" id="5000444"/>
    <dbReference type="Gramene" id="ABO94611">
        <property type="protein sequence ID" value="ABO94611"/>
        <property type="gene ID" value="OSTLU_48780"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48780"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_1"/>
    <dbReference type="OMA" id="AIMWARA"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="3"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="408" mass="43062" checksum="FF7DF5A0F12A8EC8" modified="2007-05-15" version="1">MATRDAKCRFEPIDAYRRPLGARDVLLELTHCGVCHSDVHAAAGHLRRALGATEYPAVPGHELAGEVVAIGDGVTRFAIGDRIGVGCVVDACLACEACGAGDEHRCARGMVGTYGDEDKHGRAGTWPVGGRTMGGYATHHVVDERFGIRVPKAYPMEAAGPVMCAGVTVYDPMKRYGVGAGSAVGVVGLGGLGVMAVKIARAMGASEVVVFSRSETKRSLARRCGATAFASSEDADAMRRARGTLDLILNTVPVAHDYLRFQKLLKKRERGRPRAKQVVLGLHAGLVSGMVARGVRGENSPIVASAIGGIRATQEVMDLCAAHGIVPELEILPVSRLTEIYEALDSGNDSGVRYVLDIAAFAADVRAGRVDALRTSGPPRLVLDDRNAFGPRGVVRDLARVFCGCHVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTH8</accession>
    <name>A4RTH8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">formate C-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_36056</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>formate + acetyl-CoA = pyruvate + CoA</text>
            <dbReference type="Rhea" id="RHEA:11844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.54"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.54" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416311.1">
        <property type="nucleotide sequence ID" value="XM_001416274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTH8"/>
    <dbReference type="STRING" id="436017.A4RTH8"/>
    <dbReference type="GeneID" id="5000337"/>
    <dbReference type="Gramene" id="ABO94604">
        <property type="protein sequence ID" value="ABO94604"/>
        <property type="gene ID" value="OSTLU_36056"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36056"/>
    <dbReference type="eggNOG" id="ENOG502QSG9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023898_0_0_1"/>
    <dbReference type="OMA" id="CAKVSIE"/>
    <dbReference type="OrthoDB" id="10256780at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050244">
        <property type="entry name" value="Auton_GlycylRad_Cofactor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30191">
        <property type="entry name" value="FORMATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30191:SF0">
        <property type="entry name" value="FORMATE ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000379">
        <property type="entry name" value="For_Ac_trans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0556">Organic radical</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="11">
        <location>
            <begin position="3"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="10">
        <location>
            <begin position="615"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="9">
        <location>
            <position position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="738" mass="81436" checksum="785AA010151FC347" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTK6</accession>
    <name>A4RTK6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416058.1">
        <property type="nucleotide sequence ID" value="XM_001416021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTK6"/>
    <dbReference type="GeneID" id="5000307"/>
    <dbReference type="Gramene" id="ABO94350">
        <property type="protein sequence ID" value="ABO94350"/>
        <property type="gene ID" value="OSTLU_29845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29845"/>
    <dbReference type="HOGENOM" id="CLU_627607_0_0_1"/>
    <dbReference type="OrthoDB" id="498243at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="48166" checksum="20EC6B92C0EA71EA" modified="2007-05-15" version="1">MRVGQDERVSLIPERTAGDDGAPDASFSSSTRARACLNTHRSKLTWACVAVVVALGAVCGVEFKLERDREIACHTRTDRGMGGPGVVRLGEGLTPRRVGDFGDAAAAAKAFPLRAGHDDYSKYDSVALKELVMEHLRGKCEGSGLPVFLHIPKTGGTTIETVLGTLGIDVGYCHKRPFEFRKKYIGYEQWHTPPAAEVPDSFAIVRNPYSRAQSEFLWRMNWLDKALFHSLRPGYDPENCKKFENHIKQQVHDAHKSELSQCYQEVEYTIQGMNECDGKIAARLNVESHWLPQSVTAASASRLFRFEECMGPEEGTCPRVRGEGEQPNVVSFLRSRFHPAVSMASHENDWNAAVVKPNLHACWENMNPSVLNAFNAFFKHDVSAFGYEMVTPAHALDAPDGGFHYAPALALAPKTLGEIQAELPSGDVVQANVGPQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTM1</accession>
    <name>A4RTM1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416046.1">
        <property type="nucleotide sequence ID" value="XM_001416009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTM1"/>
    <dbReference type="GeneID" id="5000387"/>
    <dbReference type="Gramene" id="ABO94338">
        <property type="protein sequence ID" value="ABO94338"/>
        <property type="gene ID" value="OSTLU_29824"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29824"/>
    <dbReference type="HOGENOM" id="CLU_774753_0_0_1"/>
    <dbReference type="OMA" id="WFQLPAK"/>
    <dbReference type="OrthoDB" id="498449at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="40129" checksum="0D03F17CFC40D951" modified="2007-05-15" version="1">MTGHTDAVVERNFNRWLERVQDNPVRFLSRAENDEGSGVSRAFFLDVRDAQHFASTRLRWSSNVPLRALDEGAAYLIPPRTARFALICDADANVDEAAKKFESDFKGVAWSLEAAFAGTPAFFDACAAIDESDATESKYNGLFEVVRGGGTPAPRDRLRLWQPSPELARWLPSVERKMDAFKDGRRPTCLDVGSGAGRDAVWVASRGWNVVAIDNDKRGLDRCRSLAERHGVEASVRTLDLDLNKRASEETLATIDKILALESWSPVLAVYAVRYLHKPFVRDLPRMLPNRSAVLWFHFMRGCERTSVGRPTKDRDLLEPNELRDVFALWDVIIDDVVELPDGRPVSSFAVVRGAKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTR0</accession>
    <name>A4RTR0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416830.1">
        <property type="nucleotide sequence ID" value="XM_001416793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTR0"/>
    <dbReference type="GeneID" id="5000781"/>
    <dbReference type="Gramene" id="ABO95123">
        <property type="protein sequence ID" value="ABO95123"/>
        <property type="gene ID" value="OSTLU_30352"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30352"/>
    <dbReference type="HOGENOM" id="CLU_2578190_0_0_1"/>
    <dbReference type="OrthoDB" id="10560107at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="81" mass="9227" checksum="F449A21C6AA212D6" modified="2007-05-15" version="1">MKQSAITARKRELRERIAELMSKRGKIGKKNFGKSLERKKLTEEIKRLTRERASVCANAGGADEEEGEDLVRADEDAEMMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTT2</accession>
    <name>A4RTT2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC(ATP-binding) family transporter: cobalt ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_6452</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416551.1">
        <property type="nucleotide sequence ID" value="XM_001416514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTT2"/>
    <dbReference type="STRING" id="436017.A4RTT2"/>
    <dbReference type="GeneID" id="5000696"/>
    <dbReference type="Gramene" id="ABO94844">
        <property type="protein sequence ID" value="ABO94844"/>
        <property type="gene ID" value="OSTLU_6452"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6452"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_1"/>
    <dbReference type="OMA" id="SWKMEMG"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060586">
        <property type="term" value="P:multicellular organismal-level iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050095">
        <property type="entry name" value="ECF_ABC_transporter_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43553:SF1">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 11, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43553">
        <property type="entry name" value="HEAVY METAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="18"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="25529" checksum="397AB3FC97058B39" modified="2007-05-15" version="1" fragment="single">RGRASTRPRASRDAPPFVDARAVSYAPAGAGAPVLRDVALALPRRGLTLIVGRSGTGKSTLLTLIAGLSEPTTGRVTLGGDGAEDARATTAADRLAKVGIVFQFPERHFLGKTVLQELTFGWPTSANAFARRRALAYRMHDALHAVGMEGVPLDTEVRTLSGGYKRRLALAIQLVRDPAVLCLDEPLAGLDWSTRAEVTALLDDLKRDRAVVVVSHDVEEIQPITDRAFRMEQMGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU69</accession>
    <name>A4RU69_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUS-like FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_86671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416620.1">
        <property type="nucleotide sequence ID" value="XM_001416583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU69"/>
    <dbReference type="STRING" id="436017.A4RU69"/>
    <dbReference type="GeneID" id="5000636"/>
    <dbReference type="Gramene" id="ABO94913">
        <property type="protein sequence ID" value="ABO94913"/>
        <property type="gene ID" value="OSTLU_86671"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86671"/>
    <dbReference type="eggNOG" id="KOG2334">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_3_0_1"/>
    <dbReference type="OMA" id="GPIRTNS"/>
    <dbReference type="OrthoDB" id="10262250at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052582">
        <property type="entry name" value="tRNA-DUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="6">
        <location>
            <begin position="17"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="345" mass="38873" checksum="56A48FC271D21A14" modified="2007-05-15" version="1">MAAPDGAREFYTGKNVCAPMVRISTLATRLLAHEYGADLVYGEELVDKRFMHCRRILNKELGSVDFIDAKGTLTFRTVPEERERVVFQVGTSSAASALKSAELVARDVAAIDVNMGCPKHFSTSGGMGARLLSQPELVRDILTTLRRNLPSTTHVTCKIRLLESERETAELAKMIESCGVSAFAVHGRYIPQRPREPAHWNLIKNVVEAVDCPVIANGDVECYEDFARIRAQTGAASAMCARGAQWNLSIFRPEGMLPIDVVKKHFVQRAIEYDNPWNFTKFQLREILVHNKRMASDEGQCLNKCKTWDELAELYSLEDVLKESREKRRRAALRDDDEYTDTVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU99</accession>
    <name>A4RU99_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416635.1">
        <property type="nucleotide sequence ID" value="XM_001416598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU99"/>
    <dbReference type="GeneID" id="5000877"/>
    <dbReference type="Gramene" id="ABO94928">
        <property type="protein sequence ID" value="ABO94928"/>
        <property type="gene ID" value="OSTLU_30546"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30546"/>
    <dbReference type="HOGENOM" id="CLU_682225_0_0_1"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="404" mass="43576" checksum="696D9E304CF6112A" modified="2007-05-15" version="1">MAEDGDDPGLVSFDELASVGTMRAEDAPRGSSPAANEEDSFGSATSEGQASPAPTMMRSVLTRKPSVAALKAMLMSERDEEGAGEGSETDEDEGVCSLSEFAMVLNAAAWDDASVGALGVEVIVKQLELLRGKIAPEASLSSMLGFDLAEDLSVRANSAGMVSVGAIGNVLYRGLSRSRSVATLSSDRERFEDILDRRAVKNISKVLGGGDEDAIITSEDLKAKLDYYGVRSSMTDIISIMTQADIESTGVVKVGDLSRLLARELEQLRGLLDEKVDNSKSERFRVSLDIERDGAETSNSLLKGQATFGVLQRFPTARKDRQKPGRLLWAKDDEMCAVCLFDRSGTMMVEEQGQLIDLPTKLDYFTDVARDADTRTIVHLPAPPPQEQEKKKGGFASFFCCFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUI1</accession>
    <name>A4RUI1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Patatin</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_30628</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lipolytic acyl hydrolase (LAH).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NTE family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the patatin family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416964.1">
        <property type="nucleotide sequence ID" value="XM_001416927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUI1"/>
    <dbReference type="STRING" id="436017.A4RUI1"/>
    <dbReference type="GeneID" id="5000896"/>
    <dbReference type="Gramene" id="ABO95257">
        <property type="protein sequence ID" value="ABO95257"/>
        <property type="gene ID" value="OSTLU_30628"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30628"/>
    <dbReference type="eggNOG" id="KOG2968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_1_3_1"/>
    <dbReference type="OMA" id="CEMLVIT"/>
    <dbReference type="OrthoDB" id="421051at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056556">
        <property type="entry name" value="NTE1_P-loop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF29">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24179">
        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9 10" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7 9 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="50"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="344"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="13">
        <location>
            <begin position="638"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="961"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="9">
        <location>
            <begin position="642"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="9">
        <location>
            <begin position="669"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="9">
        <location>
            <begin position="791"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="966"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="992"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="671"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1085" mass="119786" checksum="BEA4655297F5D1CA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUP1</accession>
    <name>A4RUP1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Iron hydrogenase small subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416706.1">
        <property type="nucleotide sequence ID" value="XM_001416669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUP1"/>
    <dbReference type="STRING" id="436017.A4RUP1"/>
    <dbReference type="GeneID" id="5000576"/>
    <dbReference type="Gramene" id="ABO94999">
        <property type="protein sequence ID" value="ABO94999"/>
        <property type="gene ID" value="OSTLU_33837"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33837"/>
    <dbReference type="eggNOG" id="KOG2439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018240_0_0_1"/>
    <dbReference type="OMA" id="GYLHHVL"/>
    <dbReference type="OrthoDB" id="10253113at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070482">
        <property type="term" value="P:response to oxygen levels"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003149">
        <property type="entry name" value="Fe_hydrogenase_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00902">
        <property type="entry name" value="Fe_hyd_SSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase small subunit" evidence="2">
        <location>
            <begin position="407"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="473" mass="51004" checksum="4AFE3843D2873D86" modified="2007-05-15" version="1">MFSGAVKIAPDALNDFIAPSQDCVVALDGVALRRRKPREDDAMAVDAEPTSTFTPTMTQGDALKVSLSDCLACSGCVTSAESVLLEQQSVDEFAQACARARSDGTSVVVASVSPQSLMSLSEAYGLGVEETRARLGGLLKAGFGAARAFDTSFSRDIALVETFAEFTEWMRDGARTPMLASACPGWVCYAEKTHGELAVPHMATTKSPQQIMGRFVKSAVARELGVPAHNVYHVSVMPCYDKKLEATRDDFESDGVKDVDVVLTTGEVALLLEKAGLCHLRDAPANDFDAFVSTNEQAPESVCAAPAVSGSGGYAEYVFRRAAAELFNAPITGEIDWVKMRNADMREATLTINGEAVLRVAVAYGFRNIQNLVRSIKLKKSKHHFVEIMACPSGCLNGGGQIPAREGTANKELIDRLDDTYRENARARPMADVSTLYREWIGGNPGSSNAREALRTQYHIRAKSVGVVQLNSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUP9</accession>
    <name>A4RUP9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416997.1">
        <property type="nucleotide sequence ID" value="XM_001416960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUP9"/>
    <dbReference type="GeneID" id="5000923"/>
    <dbReference type="Gramene" id="ABO95290">
        <property type="protein sequence ID" value="ABO95290"/>
        <property type="gene ID" value="OSTLU_14688"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14688"/>
    <dbReference type="HOGENOM" id="CLU_397107_0_0_1"/>
    <dbReference type="OMA" id="GSWNEAF"/>
    <dbReference type="OrthoDB" id="498526at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671976" description="Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="694" mass="73636" checksum="D377A965DD7FAB2B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV72</accession>
    <name>A4RV72_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416792.1">
        <property type="nucleotide sequence ID" value="XM_001416755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV72"/>
    <dbReference type="GeneID" id="5000919"/>
    <dbReference type="Gramene" id="ABO95085">
        <property type="protein sequence ID" value="ABO95085"/>
        <property type="gene ID" value="OSTLU_14816"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14816"/>
    <dbReference type="eggNOG" id="ENOG502S7BP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070191_0_0_1"/>
    <dbReference type="OMA" id="FKTLAWG"/>
    <dbReference type="OrthoDB" id="45740at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="291" mass="32708" checksum="9C5388B3483CD1E4" modified="2007-05-15" version="1">MATTTHARPVRAYADRRTVVRREIKREDFESLRDFERARSGERASESAKDSERGIPVTLSSSSEGENESAMMYTEPPRRATARRKGAFDARRAASAAFQWSVIGGVVYSVRRAQRRSEDVSKNLARRFAYADAEPDALVGTRWRVYADIGRESGTWMPPAWGQSGMRLVCPIAIEFKDNGVVEPIATGAFTPTKFEAGTWSIDGDTLRFNLKMVGGLRRGDIEFGEESLYFKTLAWGDKVSANKGRMLVNQTRFLIRREWRSVGTFKTERIAADEDAGAQLVPPMRVRVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVC3</accession>
    <name>A4RVC3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416816.1">
        <property type="nucleotide sequence ID" value="XM_001416779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVC3"/>
    <dbReference type="GeneID" id="5001022"/>
    <dbReference type="Gramene" id="ABO95109">
        <property type="protein sequence ID" value="ABO95109"/>
        <property type="gene ID" value="OSTLU_30923"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30923"/>
    <dbReference type="HOGENOM" id="CLU_1513014_0_0_1"/>
    <dbReference type="OMA" id="MNENMER"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="178" mass="20960" checksum="2F42C6AFB7069A30" modified="2007-05-15" version="1">MRAVRERSKANLAARVKEEATRRTVDRAAAKSPPPTTVSPRVEDDLRRYKELGETRKELVEARVRARAPVRRHEGFGETPAYLRRRKAELLAEMNENMERALAEIERRRVERALERQTLEDERARRAREAAKRRQALRARAEIDADKATPIERRRHALELERTRELFARARVRAYECI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVC7</accession>
    <name>A4RVC7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_30927</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417115.1">
        <property type="nucleotide sequence ID" value="XM_001417078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVC7"/>
    <dbReference type="GeneID" id="5001462"/>
    <dbReference type="Gramene" id="ABO95408">
        <property type="protein sequence ID" value="ABO95408"/>
        <property type="gene ID" value="OSTLU_30927"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30927"/>
    <dbReference type="HOGENOM" id="CLU_977920_0_0_1"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="2"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="285" mass="30679" checksum="905049019572E18F" modified="2007-05-15" version="1">MVSYVVARGDSLFSIAASHGVSTDDLVEANALGLRRSIEVGQSLHVPVNIDRASFAVRAKLRATDGRVGTTPATRKLFLRDVWSPQRSSHSTMTFGSTTGKALPSLQVFGAASFVVAIMLTLVSRKPSRAVQKTYDDERQMAATVSAPVPESDALTDGGDVVVDEITETIEIRSASGKTKQISMPEPSDEEDSNDDGPRWVGEVNPPDKKGVTPTLPKSAKKVDVARLEMRANRRAQSSARRLQRSSSRTAIRQEGHGASALPALVGGIIFDLQSTIERLRSKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVR5</accession>
    <name>A4RVR5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein RFT1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RFT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417192.1">
        <property type="nucleotide sequence ID" value="XM_001417155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVR5"/>
    <dbReference type="GeneID" id="5001451"/>
    <dbReference type="Gramene" id="ABO95485">
        <property type="protein sequence ID" value="ABO95485"/>
        <property type="gene ID" value="OSTLU_31071"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31071"/>
    <dbReference type="HOGENOM" id="CLU_2137701_0_0_1"/>
    <dbReference type="OMA" id="MWYASIS"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007594">
        <property type="entry name" value="RFT1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04506">
        <property type="entry name" value="Rft-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="113" mass="12677" checksum="4C5E5B03C0BC23AE" modified="2007-05-15" version="1">MLQRRLGPVALLVANALSMIVRITFTSSYIRKRFASQKANARLKFLSKTYLSALVIFSIVARLSDQALRRDPSALGLLAHTGCGAIILAILLVTLYFYERDAFLYLSRHDKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVR8</accession>
    <name>A4RVR8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_31074</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase A22B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417194.1">
        <property type="nucleotide sequence ID" value="XM_001417157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVR8"/>
    <dbReference type="GeneID" id="5001452"/>
    <dbReference type="Gramene" id="ABO95487">
        <property type="protein sequence ID" value="ABO95487"/>
        <property type="gene ID" value="OSTLU_31074"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31074"/>
    <dbReference type="eggNOG" id="KOG2442">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023799_4_1_1"/>
    <dbReference type="OMA" id="KDYCVLF"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030660">
        <property type="term" value="C:Golgi-associated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
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        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
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        <property type="entry name" value="Preselin/SPP"/>
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        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF75">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="329"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
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        <location>
            <begin position="109"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="17"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003012"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO95487.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="557" mass="61060" checksum="E07A36C7F3665937" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVV0</accession>
    <name>A4RVV0_OSTLU</name>
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        <submittedName>
            <fullName evidence="5">Ribosomal protein L9, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="primary">RPL9</name>
        <name evidence="5" type="ORF">OSTLU_45591</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
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        <location>
            <begin position="12"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="99"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="191" mass="21479" checksum="387BC7D750EE5532" modified="2007-05-15" version="1">MRLIKREIKIAVPEGVTVTACKARKISVTGPRGSLHRDFHHIPKLDLTLNEENEVVATMWFASNKLSGSLRTTVSHISNLFDGVTKGFRYKMRAVYAHFPVNINIEKNGTVVEIRNFLGEKRTRVCNMLEGVKSYRDESVKDCIVLEGNDIDNVSKSAALIHMACLVKKKDIRKFLDGIYVSEKGTIETEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVY3</accession>
    <name>A4RVY3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417489.1">
        <property type="nucleotide sequence ID" value="XM_001417452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVY3"/>
    <dbReference type="GeneID" id="5001392"/>
    <dbReference type="Gramene" id="ABO95782">
        <property type="protein sequence ID" value="ABO95782"/>
        <property type="gene ID" value="OSTLU_31146"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31146"/>
    <dbReference type="HOGENOM" id="CLU_1550110_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="173" mass="19356" checksum="CF6013E00B34F0A4" modified="2007-05-15" version="1">MGQNCCKPKYWHDELLGAVTFGPRVGCQEIGCGSTYHWDDLGNVAWRFKDKAWKRGGALRVELEEFLDRAMERTEGAVEEPRLKCTASACCCGGCWNPDFVTPELVEEFSKVLEENKNKKLSDMGLQCRAMCLGVRGGHGATPTLFVLVEKVGDYERFTPSESYAIDRTCVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW17</accession>
    <name>A4RW17_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417507.1">
        <property type="nucleotide sequence ID" value="XM_001417470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW17"/>
    <dbReference type="STRING" id="436017.A4RW17"/>
    <dbReference type="GeneID" id="5001364"/>
    <dbReference type="Gramene" id="ABO95800">
        <property type="protein sequence ID" value="ABO95800"/>
        <property type="gene ID" value="OSTLU_31180"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31180"/>
    <dbReference type="eggNOG" id="KOG4300">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1931586_0_0_1"/>
    <dbReference type="OMA" id="TCGCHLN"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF96">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="14399" checksum="B9356D976795C732" modified="2007-05-15" version="1">MLARAKARAETLALGEKARFEEADATALPFDDGSFDVVVDTFSLCVIEDPSAALREVRRVLRSKGRAVLIEHSKSDVGALGAYQDLTSAPVKRMSKGCVWNQDVESLVRQSGMRVVKTQRALLGLLVVVEAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW35</accession>
    <name>A4RW35_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_8313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417516.1">
        <property type="nucleotide sequence ID" value="XM_001417479.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW35"/>
    <dbReference type="STRING" id="436017.A4RW35"/>
    <dbReference type="GeneID" id="5001432"/>
    <dbReference type="Gramene" id="ABO95809">
        <property type="protein sequence ID" value="ABO95809"/>
        <property type="gene ID" value="OSTLU_8313"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8313"/>
    <dbReference type="eggNOG" id="KOG2241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_6_5_1"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="164" mass="17223" checksum="07A90A10BADDD859" modified="2007-05-15" version="1" fragment="single">PVDVSRLELVVGTVRSVKRHPDADSLYVEEIDLGGDAPRQVVSGLVKHISEDDFTGLRVVCVANMKPSKMRGVESTAMVLCGTNAEGKTEPVAPPAGAANGARVSCEGFVGDADPTLNPRKKIFETVSIDFSVTPEGIAAYKGVPFACAEGPCTLPTIREGVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW57</accession>
    <name>A4RW57_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417526.1">
        <property type="nucleotide sequence ID" value="XM_001417489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW57"/>
    <dbReference type="GeneID" id="5001256"/>
    <dbReference type="Gramene" id="ABO95819">
        <property type="protein sequence ID" value="ABO95819"/>
        <property type="gene ID" value="OSTLU_31220"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31220"/>
    <dbReference type="HOGENOM" id="CLU_2125247_0_0_1"/>
    <dbReference type="OrthoDB" id="10612477at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="114" mass="11823" checksum="0ECCBEA4A823276A" modified="2007-05-15" version="1">MVKIFVKTGKPWASGSSSVVRVVLCANDVDAVARKIAKTLGPAALNRRGEFKATGVTEFAAEDARAASASTFLGYPTPASVAIEVSGCDRRAGAFTVKAFHLALDEGCGVVYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW70</accession>
    <name>A4RW70_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417531.1">
        <property type="nucleotide sequence ID" value="XM_001417494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW70"/>
    <dbReference type="GeneID" id="5001264"/>
    <dbReference type="Gramene" id="ABO95824">
        <property type="protein sequence ID" value="ABO95824"/>
        <property type="gene ID" value="OSTLU_31233"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31233"/>
    <dbReference type="HOGENOM" id="CLU_2502021_0_0_1"/>
    <dbReference type="OrthoDB" id="10586835at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="86" mass="9373" checksum="DEF169DB9AF3B3F1" modified="2007-05-15" version="1">MTAPREKPKPEEPSADEILAQKSKKELAAEMEKLRLVRERREQQRLARLEADGGVDRYAPGAGKKAGGGGDEDSDSSDSDEDSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWI7</accession>
    <name>A4RWI7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417337.1">
        <property type="nucleotide sequence ID" value="XM_001417300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWI7"/>
    <dbReference type="GeneID" id="5001537"/>
    <dbReference type="Gramene" id="ABO95630">
        <property type="protein sequence ID" value="ABO95630"/>
        <property type="gene ID" value="OSTLU_31350"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31350"/>
    <dbReference type="HOGENOM" id="CLU_2709246_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="8425" checksum="8F5DC85658F138A8" modified="2007-05-15" version="1">MPTWRCARRGTRTRGASRASRARRRRRSTSRAGAMECYTGKHAFKRASERRGPMRDAREATRERARPFSGVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWL4</accession>
    <name>A4RWL4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417598.1">
        <property type="nucleotide sequence ID" value="XM_001417561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWL4"/>
    <dbReference type="GeneID" id="5001571"/>
    <dbReference type="Gramene" id="ABO95891">
        <property type="protein sequence ID" value="ABO95891"/>
        <property type="gene ID" value="OSTLU_31377"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31377"/>
    <dbReference type="HOGENOM" id="CLU_1520303_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="115"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="177" mass="19838" checksum="6E4EF850D7879279" modified="2007-05-15" version="1">MIEMSVEKCHQRTHALAKLIKCAREEDQEMISGALDVVERVRARVEDAGGDAREETRGGGGASTTTTFDHAAFERRMDARVDRLLELVVNAVQRNATLVSAETMTTTRGEVDALREALRAEREARARDVERLTADVERLKRERADAAAATTTSGRPELDARRRRLQGLYRELQTLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWV0</accession>
    <name>A4RWV0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417639.1">
        <property type="nucleotide sequence ID" value="XM_001417602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWV0"/>
    <dbReference type="GeneID" id="5001705"/>
    <dbReference type="KEGG" id="olu:OSTLU_92682"/>
    <dbReference type="eggNOG" id="ENOG502SVV1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072906_0_0_1"/>
    <dbReference type="OMA" id="SVVWEKF"/>
    <dbReference type="OrthoDB" id="1711508at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="35058" checksum="AFDD37C6F91BBBC9" modified="2007-05-15" version="1" fragment="single">LLVFDLNGLFVERFRNGKFTRPHAVDAIETERAVEIEDAVPRASSPVSSRTRGAATRLEVVEPDFRVGRHNHYVRRYTEEFLRWAHGRFDVAVWSSAMEVNTTAMVENIWPSDLRSKIAFVLNQDHCAVDGVMKTKGGSKGTKPKFLKPLSVVWEKFADRFDAMNTLLIDDDAYKAIRNPANTAIHPKPFSVATRDSDDGLSANGALRKYLARLLASDSVPDFVKANRFIDGQHDERSNEGFVEDVAKSIETVNAKLAALRVQEKVSRQKTKPEMRIPLPKSLIMRNAAKTRTIAPVEPVVTPTSERTRSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX53</accession>
    <name>A4RX53_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_31572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417933.1">
        <property type="nucleotide sequence ID" value="XM_001417896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX53"/>
    <dbReference type="STRING" id="436017.A4RX53"/>
    <dbReference type="GeneID" id="5001982"/>
    <dbReference type="Gramene" id="ABO96226">
        <property type="protein sequence ID" value="ABO96226"/>
        <property type="gene ID" value="OSTLU_31572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31572"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024730_0_0_1"/>
    <dbReference type="OMA" id="VMPNETT"/>
    <dbReference type="OrthoDB" id="42736at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="15"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="118"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="189"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="260"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="437"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="536" mass="59851" checksum="B4590575A43E695F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXM1</accession>
    <name>A4RXM1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Bifunctional dihydrofolate reductase-thymidylate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_49676</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15009"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 14">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">In the C-terminal section; belongs to the thymidylate synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">In the N-terminal section; belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417778.1">
        <property type="nucleotide sequence ID" value="XM_001417741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXM1"/>
    <dbReference type="STRING" id="436017.A4RXM1"/>
    <dbReference type="GeneID" id="5001729"/>
    <dbReference type="Gramene" id="ABO96071">
        <property type="protein sequence ID" value="ABO96071"/>
        <property type="gene ID" value="OSTLU_49676"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49676"/>
    <dbReference type="eggNOG" id="KOG0673">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1324">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021669_2_2_1"/>
    <dbReference type="OMA" id="ILCAWNV"/>
    <dbReference type="OrthoDB" id="766at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.572.10:FF:000002">
        <property type="entry name" value="Possible thymidylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012262">
        <property type="entry name" value="DHFR-TS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002497">
        <property type="entry name" value="PRK01827.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548:SF2">
        <property type="entry name" value="THYMIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="THYMIDYLATE SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000389">
        <property type="entry name" value="DHFR-TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 14" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DHFR" evidence="17">
        <location>
            <begin position="5"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="active site" evidence="15 16">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000389-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO96071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="499" mass="55852" checksum="5683182B5A3A8000" modified="2007-05-15" version="1">MNDGKFQVVVAATREGGIGRENALPWRLAGDMGYFKKITSETRDGDAMNAVVMGRKTWESIPGKFRPLPGRLNIVLSRSGGLAEANDENNNGAETLPEGVLVRKSIDDALSAISSSEKRIEKTFVIGGAQIYEEALQSEKCEAVHLTEVEGEFECDAFIPKIDATKFKLYGQSKPMIEKGTRFQFLTYVTADAESGKFRPKADEVLPAGCSIKHEEYQYLEMIREIIDQGAVKGDRTGTGTISTFGNQMRFDLRRSFPLLTTKRVFWRGVAEELLWFVAGETNANKLAEKKINIWDGNGSREYLDSIGLTEREVGDLGPVYGFQWRHFGAEYTNMHADYTGKGVDQLAEVIHKIKNNPNDRRILLTAWNPAALKEMALPPCHMFCQFYVANGELSCQMYQRSCDMGLGVPFNIASYSLLTCMIAQVCGLKPGDFVHCCGDTHVYSNHVEPLEKQLACEPRPFPILKINPEKKDIDSFTFDDFEIVGYDPHPKIEMKMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXQ3</accession>
    <name>A4RXQ3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417797.1">
        <property type="nucleotide sequence ID" value="XM_001417760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXQ3"/>
    <dbReference type="CAZy" id="GT60">
        <property type="family name" value="Glycosyltransferase Family 60"/>
    </dbReference>
    <dbReference type="GeneID" id="5001891"/>
    <dbReference type="Gramene" id="ABO96090">
        <property type="protein sequence ID" value="ABO96090"/>
        <property type="gene ID" value="OSTLU_31775"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31775"/>
    <dbReference type="eggNOG" id="ENOG502RZFG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_345271_0_0_1"/>
    <dbReference type="OMA" id="HKRCKMC"/>
    <dbReference type="OrthoDB" id="76265at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021067">
        <property type="entry name" value="Glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496:SF9">
        <property type="entry name" value="[SKP1-PROTEIN]-HYDROXYPROLINE N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496">
        <property type="entry name" value="GLCNAC TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11397">
        <property type="entry name" value="GlcNAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="819" mass="90996" checksum="4D3F2E7D103D5644" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXT3</accession>
    <name>A4RXT3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">15-cis-phytoene synthase</fullName>
            <ecNumber evidence="3">2.5.1.32</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_12559</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34475"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.32"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="3"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418049.1">
        <property type="nucleotide sequence ID" value="XM_001418012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXT3"/>
    <dbReference type="STRING" id="436017.A4RXT3"/>
    <dbReference type="GeneID" id="5002137"/>
    <dbReference type="Gramene" id="ABO96342">
        <property type="protein sequence ID" value="ABO96342"/>
        <property type="gene ID" value="OSTLU_12559"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12559"/>
    <dbReference type="eggNOG" id="KOG1459">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037269_4_0_1"/>
    <dbReference type="OMA" id="YRCILEA"/>
    <dbReference type="OrthoDB" id="6600518at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046905">
        <property type="term" value="F:15-cis-phytoene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000004">
        <property type="entry name" value="Phytoene synthase chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480">
        <property type="entry name" value="BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="31654" checksum="E93021033A01FD0F" modified="2007-05-15" version="1">MTPEKQRAIWAIYVWCRRTDELVDGPNASHITPEALDRWEERLEGIFDGKPVDMIDATLCDTLSRFPVDIQPFRDMIDGMRMDLVKPRYETFDELYEYCYRVAGTVGLMSMPIMGCDENFQGDVKKVYKAALALGLANQLTNILRDVGEDAQTRNRIYVPIEDLNRFGITEQEVLRGMFSPSTGKVDDRWVAFMKFQIERARQVFKDAEDGVNCLHKDARWPVWSALDVYRNILDAIEANGYNNFNQRAYVPKVEKFLMLPQSYLKAQKAQMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXU0</accession>
    <name>A4RXU0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_38770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418054.1">
        <property type="nucleotide sequence ID" value="XM_001418017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXU0"/>
    <dbReference type="STRING" id="436017.A4RXU0"/>
    <dbReference type="GeneID" id="5002139"/>
    <dbReference type="Gramene" id="ABO96347">
        <property type="protein sequence ID" value="ABO96347"/>
        <property type="gene ID" value="OSTLU_38770"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38770"/>
    <dbReference type="eggNOG" id="ENOG502QT8G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011252_1_0_1"/>
    <dbReference type="OMA" id="EFRDNAS"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005747">
        <property type="entry name" value="MutS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48466:SF2">
        <property type="entry name" value="OS10G0509000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48466">
        <property type="entry name" value="OS10G0509000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005814">
        <property type="entry name" value="MutS_YshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="5">
        <location>
            <begin position="82"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="505"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="376"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="77326" checksum="1EA15DFA5046A518" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="113" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXZ9</accession>
    <name>A4RXZ9_OSTLU</name>
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        <recommendedName>
            <fullName evidence="9">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="9">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_31874</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 18">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418083.1">
        <property type="nucleotide sequence ID" value="XM_001418046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXZ9"/>
    <dbReference type="STRING" id="436017.A4RXZ9"/>
    <dbReference type="GeneID" id="5001998"/>
    <dbReference type="Gramene" id="ABO96376">
        <property type="protein sequence ID" value="ABO96376"/>
        <property type="gene ID" value="OSTLU_31874"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31874"/>
    <dbReference type="eggNOG" id="KOG0952">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000335_0_2_1"/>
    <dbReference type="OMA" id="RFGFAWI"/>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd18023">
        <property type="entry name" value="DEXHc_HFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052247">
        <property type="entry name" value="Meiotic_Crossover_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47835:SF3">
        <property type="entry name" value="HELICASE FOR MEIOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47835">
        <property type="entry name" value="HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="39"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="266"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="13">
        <location>
            <begin position="960"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="13">
        <location>
            <begin position="992"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="13">
        <location>
            <begin position="1013"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="875"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="937"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="889"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="947"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO96376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1060" mass="118816" checksum="1EC7DA7CE6F1907B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY74</accession>
    <name>A4RY74_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_24618</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417844.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABO96174"/>
        <property type="gene ID" value="OSTLU_24618"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="498631at2759"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96174.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="774" mass="83351" checksum="940BCD512200BB4A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYE5</accession>
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            <fullName evidence="7">STI1 domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="8" type="ORF">OSTLU_45893</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">CCE9901</strain>
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        <subcellularLocation>
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    </dbReference>
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        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="565" mass="62321" checksum="B25308E889CF6948" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYW4</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_32166"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_1236798_0_0_1"/>
    <dbReference type="OMA" id="ENERAMG"/>
    <dbReference type="OrthoDB" id="10528444at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="224" mass="23780" checksum="E99281B5FD744D11" modified="2007-05-15" version="1">MADAANECAAKTVLPRRADEVIETLRAVARCGDDFSRAMVPGSGCALLDAMDGGKALMTARRNADVATAYFEALASALGVENERAMGLFRALATVNVFEHDDRPTVFGVMDVFQGLACSASAQSAVAVAAALEKSGALGDFIARAFVTMAAREDDADAIDVAMSRRFFAFVIFVLRARSERFQALAFAGVESAATPVVARLCLSRAGSEPNAAALYQEIKRRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYZ2</accession>
    <name>A4RYZ2_OSTLU</name>
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        <recommendedName>
            <fullName evidence="10">Pyruvate dehydrogenase E1 component subunit beta</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_12625</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 10">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="10"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418477.1">
        <property type="nucleotide sequence ID" value="XM_001418440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYZ2"/>
    <dbReference type="STRING" id="436017.A4RYZ2"/>
    <dbReference type="GeneID" id="5002344"/>
    <dbReference type="Gramene" id="ABO96770">
        <property type="protein sequence ID" value="ABO96770"/>
        <property type="gene ID" value="OSTLU_12625"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12625"/>
    <dbReference type="eggNOG" id="KOG0524">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_1_1"/>
    <dbReference type="OMA" id="WYANCPG"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000006">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB_mito-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006667">
        <property type="entry name" value="PRK09212.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008854">
        <property type="entry name" value="PRK11892.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624:SF96">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="327" mass="35441" checksum="F3DA5684B4BFD582" modified="2007-05-15" version="1">MTVRDALNSALSEEMARDEKVFIMGEEVGDYQGAYKITKGLLQKFGADRVRDTPITEAGFTGLGVGAAFMGLKPIVEFMTFNFSMQAIDHIVNSAAKTLYMSAGAISAPIVFRGPNGAAAGVGAQHSQCFAAWYMSIPGLKVLAPYDAEDARGLMKAAIRDPDPVVFLENELLYGQEFALPKEAMDEEFVLPIGKAVVMKPGADVTLVAFSKMVGYCLEAAEQLREQGIDAEVINLRSLRPLDRGALAASVRKTNRMVVVEEGWPQCGVGAEIATVVNEDAFDYLDAPVERIAGVDIPMPYAENLEKMALPTVEDIVRVATRVCYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZA1</accession>
    <name>A4RZA1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_9589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418539.1">
        <property type="nucleotide sequence ID" value="XM_001418502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZA1"/>
    <dbReference type="STRING" id="436017.A4RZA1"/>
    <dbReference type="GeneID" id="5002536"/>
    <dbReference type="KEGG" id="olu:OSTLU_9589"/>
    <dbReference type="eggNOG" id="KOG2445">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162320_0_0_1"/>
    <dbReference type="OMA" id="RAPEASN"/>
    <dbReference type="OrthoDB" id="424673at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021995">
        <property type="entry name" value="DUF3593"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35473">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35473:SF3">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12159">
        <property type="entry name" value="DUF3593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="83" mass="8882" checksum="4C4BE0D269ADBBEC" modified="2007-05-15" version="1" fragment="single">LFQVGLAPYLAYLWFLRDARATPRASNFGARFLLLFVAATIPAGIVAKMRYGDILANVDALHGSSESLLTVSNALFAYGFGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZS3</accession>
    <name>A4RZS3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RNase T2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418848.1">
        <property type="nucleotide sequence ID" value="XM_001418811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZS3"/>
    <dbReference type="STRING" id="436017.A4RZS3"/>
    <dbReference type="GeneID" id="5003050"/>
    <dbReference type="Gramene" id="ABO97141">
        <property type="protein sequence ID" value="ABO97141"/>
        <property type="gene ID" value="OSTLU_92983"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92983"/>
    <dbReference type="eggNOG" id="ENOG502SGJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_947793_0_0_1"/>
    <dbReference type="OMA" id="HGTCAAW"/>
    <dbReference type="OrthoDB" id="435754at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
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        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
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        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
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        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
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        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="286" mass="30531" checksum="A5FA415A67C6937A" modified="2007-05-15" version="1" fragment="single">VIALVLARPVASSSPVESASSCPAVGTKTHFGCDDGVRATRRAFDMWELARAWTPGFCASAPRACEKGECARSAAEPALTLHGLWPSYSTATKSDGRDGCYWPQNCVKPSWYPSSEKWTYAAREIPSGAAAERIAPAWTRDGLGAHEWAKHGTCASWIDVEGTTRGMTQREFYNVTFALAEALGTPEVLLEATGSELSLADAQQAFGGASKVALGCTKSCVLLQVVQCFKRTPDGGVGEAEDCPCVGVRDSRYDNSCAERCERVRVLSPEQTGCHADIASRVASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0E9</accession>
    <name>A4S0E9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418733.1">
        <property type="nucleotide sequence ID" value="XM_001418696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0E9"/>
    <dbReference type="GeneID" id="5002941"/>
    <dbReference type="Gramene" id="ABO97026">
        <property type="protein sequence ID" value="ABO97026"/>
        <property type="gene ID" value="OSTLU_32720"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32720"/>
    <dbReference type="eggNOG" id="KOG3241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1858620_0_0_1"/>
    <dbReference type="OrthoDB" id="250548at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019351">
        <property type="entry name" value="DUF2039"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22876:SF5">
        <property type="entry name" value="CHROMOSOME 9 OPEN READING FRAME 85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22876">
        <property type="entry name" value="ZGC:101016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10217">
        <property type="entry name" value="DUF2039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="138" mass="15341" checksum="3D5948E1F214166E" modified="2007-05-15" version="1">MSGGRSRSQKHQNRVPFVAKRDIKRNEGDRERELGLRNLALQNVCKRCQQKIVWRFQMGKYKAKKPGTRGRCNKCEQKSVRMAYRSLCDACGKAHDLCPGCQHPPSEANASRDVPEACASSGSDSDAESEPASDGEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0P8</accession>
    <name>A4S0P8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gamma-tubulin complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_32821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419017.1">
        <property type="nucleotide sequence ID" value="XM_001418980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0P8"/>
    <dbReference type="STRING" id="436017.A4S0P8"/>
    <dbReference type="GeneID" id="5003012"/>
    <dbReference type="Gramene" id="ABO97310">
        <property type="protein sequence ID" value="ABO97310"/>
        <property type="gene ID" value="OSTLU_32821"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32821"/>
    <dbReference type="eggNOG" id="KOG4344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_318423_0_0_1"/>
    <dbReference type="OMA" id="CEYAACQ"/>
    <dbReference type="OrthoDB" id="66546at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF33">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="226"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="617"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="914" mass="100393" checksum="6ECC8A9201039EF7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0U7</accession>
    <name>A4S0U7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ku domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_16311</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419039.1">
        <property type="nucleotide sequence ID" value="XM_001419002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0U7"/>
    <dbReference type="STRING" id="436017.A4S0U7"/>
    <dbReference type="GeneID" id="5002739"/>
    <dbReference type="Gramene" id="ABO97332">
        <property type="protein sequence ID" value="ABO97332"/>
        <property type="gene ID" value="OSTLU_16311"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:Ku70:Ku80 complex"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF4">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ku" evidence="12">
        <location>
            <begin position="292"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="575"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="621"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="640" mass="68630" checksum="292147D50AD94C49" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S118</accession>
    <name>A4S118_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_3572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S118"/>
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    <dbReference type="Gramene" id="ABO97577">
        <property type="protein sequence ID" value="ABO97577"/>
        <property type="gene ID" value="OSTLU_3572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3572"/>
    <dbReference type="eggNOG" id="KOG1235">
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    </dbReference>
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    <dbReference type="OMA" id="HADCHEG"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF12">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="1">
        <location>
            <begin position="59"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="421" mass="47495" checksum="D5AF58940D6D12E1" modified="2007-05-15" version="1" fragment="single">IRDAEKRDEAWERQHQWGAERMRDVIEDFGGFYRKVGQIAGTAKQMMPAPYIECFSKTMDNNPPVSFREVRKTLEESLGGHLGEHFAELSRKPVATASIAQVHFGRLLDGREVAVKVQATDAAMMIGDIESMLQTTKAMRWLGLDEGLDFPTIFRAYLDVVDEEFDFTIEGAKTEEFGKLLDAAGLADRISVPQVIMSTRRVLIMRRVRGMKLLTLFNRARAQNKIPRCPTPVSKCHGAGGFGWQGVFHSMFTAWGVMMLKHGHFHTDPHPGNFMVANDGKLVLLDWGQTKRVSEVERMHMCRLSLYMANEDHVSIAREISEHGTVRLQRPTTEALSALAYAYFDTRPSPLAEMNVMDLKNSPFVQNKIVQNTQEGFFAIRSVFLLRGMLSTCGLRMSMVEAWEAIARNALVLNGEVPPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4S132</accession>
    <name>A4S132_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419081.1">
        <property type="nucleotide sequence ID" value="XM_001419044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S132"/>
    <dbReference type="GeneID" id="5003347"/>
    <dbReference type="Gramene" id="ABO97374">
        <property type="protein sequence ID" value="ABO97374"/>
        <property type="gene ID" value="OSTLU_32957"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32957"/>
    <dbReference type="HOGENOM" id="CLU_2007777_0_0_1"/>
    <dbReference type="OMA" id="KWSAGAM"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="124" mass="13947" checksum="78EB6BCC307A2F3B" modified="2007-05-15" version="1">MVFKTLWNYVKVYRAQTRALERIRAERSALEKTQREIAAMTEKNAENERALASFAKWSAGAMRENASSMEEIERVTTEMTDRLGAVSEQHVRDAYEAEARAAEAMNASRAAAVFANLDEVKGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S173</accession>
    <name>A4S173_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419314.1">
        <property type="nucleotide sequence ID" value="XM_001419277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S173"/>
    <dbReference type="GeneID" id="5003265"/>
    <dbReference type="Gramene" id="ABO97607">
        <property type="protein sequence ID" value="ABO97607"/>
        <property type="gene ID" value="OSTLU_24914"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24914"/>
    <dbReference type="eggNOG" id="ENOG502T1I1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1024477_0_0_1"/>
    <dbReference type="OrthoDB" id="524083at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037359">
        <property type="entry name" value="NST/OST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605:SF56">
        <property type="entry name" value="BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605">
        <property type="entry name" value="HEPARAN SULFATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR637359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="30232" checksum="D51DC70B1E199641" modified="2007-05-15" version="1">MVLYAGSYFVEHPIWKFEHVSRWAARRAASVGAAGPMRCSKDPALTGEQTCLPSFAVIGSHVGGMRRLKRLMSQHDMLTTGQKTMHFFNPVYGATQGVQMCEPPELLLKAYFSAVQAGHGETWSPYDPSETMKAKRDGEAFERELGDVVTGDWSDTYFNCACCASTMKRLMPNLRPIVVLRDPVGRAMARYVEENHPHGTPVEASGLSACALKENGYTWGATAKKTKEYLEQCVKEADGADSGTLTRECLDFHSVLGWSMYAEYLEFARNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S190</accession>
    <name>A4S190_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome C biogenesis protein transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CCDA</name>
        <name evidence="12" type="ORF">OSTLU_10432</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DsbD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419323.1">
        <property type="nucleotide sequence ID" value="XM_001419286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S190"/>
    <dbReference type="STRING" id="436017.A4S190"/>
    <dbReference type="GeneID" id="5003273"/>
    <dbReference type="Gramene" id="ABO97616">
        <property type="protein sequence ID" value="ABO97616"/>
        <property type="gene ID" value="OSTLU_10432"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10432"/>
    <dbReference type="eggNOG" id="ENOG502QR2K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053225_0_1_1"/>
    <dbReference type="OMA" id="CYAIGHC"/>
    <dbReference type="OrthoDB" id="40974at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051790">
        <property type="entry name" value="Cytochrome_c-biogenesis_DsbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31272:SF6">
        <property type="entry name" value="CYTOCHROME C-TYPE BIOGENESIS CCDA-LIKE CHLOROPLASTIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31272">
        <property type="entry name" value="CYTOCHROME C-TYPE BIOGENESIS PROTEIN HI_1454-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome C biogenesis protein transmembrane" evidence="11">
        <location>
            <begin position="4"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="225" mass="21994" checksum="75B73B65582B4673" modified="2007-05-15" version="1" fragment="single">GATTYVTVLAAGVFTSLSPCTLSVLPLTIGYIGGYGGGGGAGEAPSAEERAKTVRVASVAFAGGLASTLAALGVVAASFGAAYGQGLGDGLPTAAAALAVAMGLNLLDVVEVSFPSFGANFDPKSVRVSPVLQAYIAGAVFALAASPCATPILATLLAYAASSGDPLSGGTLLLTYTSGYVAPLLFAATATDGLKSVMALREKSAWVNPTSGFLLVAGGTYAFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1B9</accession>
    <name>A4S1B9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_33044</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419338.1">
        <property type="nucleotide sequence ID" value="XM_001419301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1B9"/>
    <dbReference type="STRING" id="436017.A4S1B9"/>
    <dbReference type="GeneID" id="5003084"/>
    <dbReference type="Gramene" id="ABO97631">
        <property type="protein sequence ID" value="ABO97631"/>
        <property type="gene ID" value="OSTLU_33044"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33044"/>
    <dbReference type="eggNOG" id="KOG4844">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150777_1_0_1"/>
    <dbReference type="OMA" id="GYSEYYQ"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013219">
        <property type="entry name" value="Ribosomal_mS33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08293">
        <property type="entry name" value="MRP-S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="92" mass="9963" checksum="85F4FDBDD5139E0A" modified="2007-05-15" version="1">MPGVAKTATEIARVAARVFGAHLGDGRPSGRKILRAPLIGERLAAYYPKTMAALDPLFTAPDETRRKVKLERLKRRGKGPPKKGEGKRAGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1F0</accession>
    <name>A4S1F0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419354.1">
        <property type="nucleotide sequence ID" value="XM_001419317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1F0"/>
    <dbReference type="GeneID" id="5003100"/>
    <dbReference type="Gramene" id="ABO97647">
        <property type="protein sequence ID" value="ABO97647"/>
        <property type="gene ID" value="OSTLU_33076"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33076"/>
    <dbReference type="HOGENOM" id="CLU_125699_0_0_1"/>
    <dbReference type="OMA" id="ANVTACH"/>
    <dbReference type="OrthoDB" id="541597at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="19844" checksum="E606B21CC36DFE9C" modified="2007-05-15" version="1">MEITARLVRELERARRRASGEDVGENERDARAASGGERGGASTSGIGAKPGTAARGLFAPADLLSTARVAPGNHREAIADEAVRRRHPDVDGALRASERVGDLLLKREEGEIARTRRFVEELDALERDPFNGAREPPCAVEAASVRACYGANAANVTACHDLVDEYKKCGRVALRKFVSREPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1H1</accession>
    <name>A4S1H1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_42867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419147.1">
        <property type="nucleotide sequence ID" value="XM_001419110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1H1"/>
    <dbReference type="GeneID" id="5003471"/>
    <dbReference type="Gramene" id="ABO97440">
        <property type="protein sequence ID" value="ABO97440"/>
        <property type="gene ID" value="OSTLU_42867"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42867"/>
    <dbReference type="eggNOG" id="ENOG502R7JU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031758_5_1_1"/>
    <dbReference type="OMA" id="AYGDHDM"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004131">
        <property type="term" value="F:cytosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035888">
        <property type="term" value="F:isoguanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006209">
        <property type="term" value="P:cytosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01293">
        <property type="entry name" value="Bact_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052349">
        <property type="entry name" value="Metallo-hydrolase_Enzymes"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005759">
        <property type="entry name" value="PRK07583.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027:SF0">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="155"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="41805" checksum="B7A51A04D59F5F5C" modified="2007-05-15" version="1">MCLPTFVDIHTHIDKAHTCERSRNLNGTLAGADAACANDFQHWTLEDAKRRMGFAIQCAYAYGTSAMRTHLMSGEERQSKIAWEAFGKLREEWRGKVELQGVSLSVLSFFRDETKARALARMVKSYGGILGAAVSCSDAGGTPLDVHTTCGADMPKLLDVIFSLAKEYNLDVDFHCDENGNESSKGLLHISEAVIRNNFKGSVVCGHCCSLAVQPNEQAKRIIDAAREAGVTVVSLPIVNQWLQNRDPTNEATPTRRGVTRVKELARAGVPVCLSSDNTRDQFFQYGDCDMLEVFRSSVCIAHLDRPFGSWPLALAANPSRAMRLGEKSGMIAPGAKANFVLFRARNYSELFSRSQHDRVVIRDGVRIATALPDYEELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1H5</accession>
    <name>A4S1H5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Methyltransferase</fullName>
            <ecNumber evidence="13">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_42420</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Microsome membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="13"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419368.1">
        <property type="nucleotide sequence ID" value="XM_001419331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1H5"/>
    <dbReference type="STRING" id="436017.A4S1H5"/>
    <dbReference type="GeneID" id="5003252"/>
    <dbReference type="Gramene" id="ABO97661">
        <property type="protein sequence ID" value="ABO97661"/>
        <property type="gene ID" value="OSTLU_42420"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42420"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039068_5_2_1"/>
    <dbReference type="OMA" id="MTNSFYD"/>
    <dbReference type="OrthoDB" id="4310724at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030384">
        <property type="entry name" value="MeTrfase_SMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013705">
        <property type="entry name" value="Sterol_MeTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44742">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44742:SF2">
        <property type="entry name" value="24-METHYLENESTEROL C-METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08498">
        <property type="entry name" value="Sterol_MT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51685">
        <property type="entry name" value="SAM_MT_ERG6_SMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12 13" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase Erg6/SMT-type" evidence="14">
        <location>
            <begin position="35"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="317" mass="34611" checksum="83EFD28B04FF7EDF" modified="2007-05-15" version="1">MVDKGIKSYNEFFDQEDGKGVGSRILSTPDFVNKFYSLITDFYEYGWGESFHFAAREKGESFEDSIIRQEVAIAENIGLKAGMNVLDLGCGVGGPMRNIVKATGGKVTGITINEYQVGRCNTLNQQAGLEDLTEIVQGNFMDLAKVFKGRSFDGAYAIEAACHASNTTALYKQVFQVLKPGALFASYEWLRTDQYDPNNKVHVDVVDGIAEGNALPEVRTIEDCVEAAKAAGFDVQFTFDRATLGAVPWQQAMKSARRAAYLTHVLTGVLEFIGFAPKGTQAVHTMLLKAAVNLEKGGDLGIFSPMYLIVMKKPLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Q5</accession>
    <name>A4S1Q5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kri1-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_16531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KRI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419408.1">
        <property type="nucleotide sequence ID" value="XM_001419371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Q5"/>
    <dbReference type="STRING" id="436017.A4S1Q5"/>
    <dbReference type="GeneID" id="5003165"/>
    <dbReference type="Gramene" id="ABO97701">
        <property type="protein sequence ID" value="ABO97701"/>
        <property type="gene ID" value="OSTLU_16531"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16531"/>
    <dbReference type="eggNOG" id="KOG2409">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009647_2_0_1"/>
    <dbReference type="OMA" id="WDNYDPR"/>
    <dbReference type="OrthoDB" id="10252032at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018034">
        <property type="entry name" value="Kri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024626">
        <property type="entry name" value="Kri1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490:SF5">
        <property type="entry name" value="PROTEIN KRI1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490">
        <property type="entry name" value="ZINC FINGER, ZZ TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05178">
        <property type="entry name" value="Kri1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12936">
        <property type="entry name" value="Kri1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kri1-like C-terminal" evidence="3">
        <location>
            <begin position="509"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="667"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="688" mass="77086" checksum="E6395C9F7C96868E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1T6</accession>
    <name>A4S1T6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="9">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_46355</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="9"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419423.1">
        <property type="nucleotide sequence ID" value="XM_001419386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1T6"/>
    <dbReference type="STRING" id="436017.A4S1T6"/>
    <dbReference type="GeneID" id="5003201"/>
    <dbReference type="Gramene" id="ABO97716">
        <property type="protein sequence ID" value="ABO97716"/>
        <property type="gene ID" value="OSTLU_46355"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_46355"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_3_0_1"/>
    <dbReference type="OMA" id="GQGFEWA"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF111">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="10">
        <location>
            <begin position="34"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="458" mass="48699" checksum="B70413FD64ED56A1" modified="2007-05-15" version="1" fragment="single">MSRSWLDDLRRACADTRADAAALDARARDMGAHAGARPDAVCAPRTVEEVAAIVRTCARHRRPIVARGAGTGLEGGAVAYGGGCVLDTRMLRAIEIDEANMCARVGAGALKSELNAALAKRGFAFGPDPSSNPTLGGMASTGGSGLSTLKYGTTKENVRSMTVVTPDGEIIRTRAEVRKSSTGYELNALYLGAEGTLGVIVELVVKIVPLPKRRCGAIVRFPTVGAAGKTVAEATAANLSTLLRCELMNDEGIKVTNVVFQTSLPCVPTLFLEFVGNRQGEMEEDWESFLRIAKSNGSASHDFASNGEELDELWDARRGCYLGAMRYRGLEAGTNAKESVYVGDVCVPASKLSACIAATELEFKKARFPCVICAHIADGNFHCLIPFQEHERAALLALEDKVIGNAIAMGGSASGEHGVGIGKQKYIIMEHGVAHVDIQRRIKRALDPLNIMNPGKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1V5</accession>
    <name>A4S1V5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_88091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419432.1">
        <property type="nucleotide sequence ID" value="XM_001419395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1V5"/>
    <dbReference type="STRING" id="436017.A4S1V5"/>
    <dbReference type="GeneID" id="5003130"/>
    <dbReference type="KEGG" id="olu:OSTLU_88091"/>
    <dbReference type="eggNOG" id="ENOG502S1JT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1005908_0_0_1"/>
    <dbReference type="OMA" id="PIQGCMY"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969:SF9">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="28"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="274" mass="29833" checksum="F28FAE21E652F4F0" modified="2007-05-15" version="1" fragment="single">LPRAAPAPARARARRATPQRAATLRPRALGTLYDVPVSNNGARCRLLARWLGLYDDLVLTNPNDAFADGGIKSAAYAEINPQLKMPTLVAANGLRVPESEVINAYLMDAASEGARRLATPKTIEGRTNGALATRTHDQYLVPIQGAMYRGPMDRATRATQLAEIARQLRILDEICGREDGDYVAGETKSAADAALFPTLIFCDFLLPKYFGWSEGAALGGANLRRMYEAVKRDPDGAKTYDEVRGGLEAWESAGRFEKVGIVDDVADVSFQWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S205</accession>
    <name>A4S205_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419241.1">
        <property type="nucleotide sequence ID" value="XM_001419204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S205"/>
    <dbReference type="GeneID" id="5003317"/>
    <dbReference type="Gramene" id="ABO97534">
        <property type="protein sequence ID" value="ABO97534"/>
        <property type="gene ID" value="OSTLU_16603"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16603"/>
    <dbReference type="HOGENOM" id="CLU_410720_0_0_1"/>
    <dbReference type="OrthoDB" id="10561173at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="669" mass="76035" checksum="41C4BEAA1C734525" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S246</accession>
    <name>A4S246_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA/rRNA methyltransferase SpoU type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_33322</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419472.1">
        <property type="nucleotide sequence ID" value="XM_001419435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S246"/>
    <dbReference type="STRING" id="436017.A4S246"/>
    <dbReference type="GeneID" id="5003620"/>
    <dbReference type="Gramene" id="ABO97765">
        <property type="protein sequence ID" value="ABO97765"/>
        <property type="gene ID" value="OSTLU_33322"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33322"/>
    <dbReference type="eggNOG" id="ENOG502QQ5S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110125_2_1_1"/>
    <dbReference type="OMA" id="AGLDYWH"/>
    <dbReference type="OrthoDB" id="5580682at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002130">
        <property type="term" value="P:wobble position ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="TrmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="TRNA (CYTIDINE(34)-2'-O)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971:SF1">
        <property type="entry name" value="TRNA (CYTIDINE(34)-2'-O)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="6">
        <location>
            <begin position="21"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="19881" checksum="2F22A9D1DB368EA9" modified="2007-05-15" version="1">MGPNVTVRAIETASDAQRKDLHVVLVTPKIPGNTGCIARTCAASRVPLHLVAPLGFSLDDAQLKRAGLDYWKSVCVKVHDDWDAFYAYWRELGDERGRLVAFSKFGARPHAEDGAYRPGDWLLFGAETTGLPDAAMEACKATGGVRRIPIDESHVRSLNLSVSCGIGVYEALRQLDGSPTVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2P3</accession>
    <name>A4S2P3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b-c1 complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_94712</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419785.1">
        <property type="nucleotide sequence ID" value="XM_001419748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2P3"/>
    <dbReference type="STRING" id="436017.A4S2P3"/>
    <dbReference type="GeneID" id="5003773"/>
    <dbReference type="Gramene" id="ABO98078">
        <property type="protein sequence ID" value="ABO98078"/>
        <property type="gene ID" value="OSTLU_94712"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94712"/>
    <dbReference type="eggNOG" id="KOG3440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115154_3_0_1"/>
    <dbReference type="OMA" id="QTALHWV"/>
    <dbReference type="OrthoDB" id="425749at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1090.10:FF:000002">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000022">
        <property type="entry name" value="Bc1_14K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="122" mass="14285" checksum="14A0EC555F5B7EA4" modified="2007-05-15" version="1">MSRAMRKMLEPMLKSMSVNYRRTVGDELRKYGLRYDDLLDEGQDLDVGEALKRLTAEERDMRAQRLKRAIDLSMKHSYLTKEEQATQTPFDFYLTPIVERVKAERAERTALGGSQPYNRQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3B2</accession>
    <name>A4S3B2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419889.1">
        <property type="nucleotide sequence ID" value="XM_001419852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3B2"/>
    <dbReference type="STRING" id="436017.A4S3B2"/>
    <dbReference type="GeneID" id="5004238"/>
    <dbReference type="Gramene" id="ABO98182">
        <property type="protein sequence ID" value="ABO98182"/>
        <property type="gene ID" value="OSTLU_25995"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25995"/>
    <dbReference type="eggNOG" id="ENOG502QTQ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137575_0_0_1"/>
    <dbReference type="OMA" id="MRAERAF"/>
    <dbReference type="OrthoDB" id="64875at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039145">
        <property type="entry name" value="Ribosomal_mL40_metazoa/plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13359">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13359:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="134" mass="14740" checksum="6D6962BDC9E0EFDE" modified="2007-05-15" version="1">MGALPISAKAEHTTKGNKNTYLEALTKLDATEIEENLTPEELAEYEARAKAYSREKMRAERAFAADINEKIRIKKAAIAALPAGATRDAAMVEDEDLFPLKRKLPMYTPAIPGFYEDKQRLAEEAVSGGAALKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3E1</accession>
    <name>A4S3E1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_7029</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF2/ABP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419903.1">
        <property type="nucleotide sequence ID" value="XM_001419866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3E1"/>
    <dbReference type="STRING" id="436017.A4S3E1"/>
    <dbReference type="GeneID" id="5004139"/>
    <dbReference type="Gramene" id="ABO98196">
        <property type="protein sequence ID" value="ABO98196"/>
        <property type="gene ID" value="OSTLU_7029"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7029"/>
    <dbReference type="eggNOG" id="KOG3152">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054086_2_1_1"/>
    <dbReference type="OMA" id="ILAIPHC"/>
    <dbReference type="OrthoDB" id="287393at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034462">
        <property type="term" value="P:small-subunit processome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12263">
        <property type="entry name" value="RRM_ABT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039119">
        <property type="entry name" value="ABT1/Esf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034353">
        <property type="entry name" value="ABT1/ESF2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311:SF7">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="175" mass="20589" checksum="C8D6E2E7BC232368" modified="2007-05-15" version="1" fragment="single">KKPTLDAKALERVRADHARRGVVFLGTIPPFMKPTKLRQLLSVYGETDRMYLAAEDPATRAKRKKFGGNTGKKYVEGWVEFRNKKDAKRAAEMLHGREVGGKRRSAHYYDLWNIKYLPKFKWDNLTEEMEYQKALREKKLQLELSVAKKERDFYLAKLDQGKALEAMKERRAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Q9</accession>
    <name>A4S3Q9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ABCG) family transporter: multidrug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_38326</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420135.1">
        <property type="nucleotide sequence ID" value="XM_001420098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Q9"/>
    <dbReference type="STRING" id="436017.A4S3Q9"/>
    <dbReference type="GeneID" id="5004089"/>
    <dbReference type="Gramene" id="ABO98428">
        <property type="protein sequence ID" value="ABO98428"/>
        <property type="gene ID" value="OSTLU_38326"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38326"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_57_8_1"/>
    <dbReference type="OMA" id="THTELCA"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="18"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="551" mass="60613" checksum="876711C0BB86272C" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3W7</accession>
    <name>A4S3W7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_10150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420165.1">
        <property type="nucleotide sequence ID" value="XM_001420128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3W7"/>
    <dbReference type="STRING" id="436017.A4S3W7"/>
    <dbReference type="GeneID" id="5004032"/>
    <dbReference type="Gramene" id="ABO98458">
        <property type="protein sequence ID" value="ABO98458"/>
        <property type="gene ID" value="OSTLU_10150"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10150"/>
    <dbReference type="eggNOG" id="KOG0246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_2_0_1"/>
    <dbReference type="OMA" id="WRANNAR"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF20">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="3">
        <location>
            <begin position="1"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="92"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="337" mass="36611" checksum="BD8096844245E4D1" modified="2007-05-15" version="1" fragment="single">INVYARKRPLFDPEKKRGEYDVVSVKSGSTAVVHNCQMHADLKRMFVKHCAYTLSGGVFDEDAQEHDVYDRSAAPLVAGTLKGGVGALFMYGQTGSGKTHTMENIEKHAIEALFVGDGAAAGAKSIKVSYFEIAGKACVDLLQPGRVEIRLKELFEEQGDALTGQMEVELMGAKEPVVTSASDLKKVIDEGKSRRQTSATQCNASSSRSHAVMRLTVTLSDGSMGRLTLVDCAGSERKEDNTHHNEKQRKETAEINASLYALKECVRFRRLKFSGARNSNVHVPYRNSPLTRVLAECFVREDAGVAVIGTMSPASIDTEHSLATLKTINAIGGNEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S479</accession>
    <name>A4S479_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">OSTLU_11</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420225.1">
        <property type="nucleotide sequence ID" value="XM_001420188.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S479"/>
    <dbReference type="GeneID" id="5004194"/>
    <dbReference type="Gramene" id="ABO98518">
        <property type="protein sequence ID" value="ABO98518"/>
        <property type="gene ID" value="OSTLU_11"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_11"/>
    <dbReference type="eggNOG" id="KOG0368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_5_2_1"/>
    <dbReference type="OMA" id="NVIPWSG"/>
    <dbReference type="OrthoDB" id="14612at2759"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000005">
        <property type="entry name" value="Acetyl-CoA carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.460.10">
        <property type="entry name" value="Biotin dependent carboxylase carboxyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1770.10">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21385">
        <property type="entry name" value="ACCA_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0092">Biotin</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="17">
        <location>
            <begin position="10"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="157"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="18">
        <location>
            <begin position="1377"/>
            <end position="1701"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="19">
        <location>
            <begin position="1705"/>
            <end position="1991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="968"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1000"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABO98518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1994" mass="218109" checksum="E4A1A951C1A3E42D" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4K3</accession>
    <name>A4S4K3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ABCD) family transporter: long-chain fatty acid (ALDP-like protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_43996</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420280.1">
        <property type="nucleotide sequence ID" value="XM_001420243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4K3"/>
    <dbReference type="STRING" id="436017.A4S4K3"/>
    <dbReference type="GeneID" id="5004577"/>
    <dbReference type="Gramene" id="ABO98573">
        <property type="protein sequence ID" value="ABO98573"/>
        <property type="gene ID" value="OSTLU_43996"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43996"/>
    <dbReference type="eggNOG" id="KOG0064">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007587_5_2_1"/>
    <dbReference type="OMA" id="DRFWASI"/>
    <dbReference type="OrthoDB" id="422637at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF67">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="398"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="615" mass="67745" checksum="18C88F9F0A1E9FEB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4P0</accession>
    <name>A4S4P0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-galactopyranose mutase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_4114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420469.1">
        <property type="nucleotide sequence ID" value="XM_001420432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4P0"/>
    <dbReference type="STRING" id="436017.A4S4P0"/>
    <dbReference type="GeneID" id="5004593"/>
    <dbReference type="Gramene" id="ABO98762">
        <property type="protein sequence ID" value="ABO98762"/>
        <property type="gene ID" value="OSTLU_4114"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4114"/>
    <dbReference type="eggNOG" id="ENOG502QSEJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042118_0_0_1"/>
    <dbReference type="OMA" id="EYKHKPN"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008767">
        <property type="term" value="F:UDP-galactopyranose mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015899">
        <property type="entry name" value="UDP-GalPyranose_mutase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21197">
        <property type="entry name" value="UDP-GALACTOPYRANOSE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21197:SF0">
        <property type="entry name" value="UDP-GALACTOPYRANOSE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03275">
        <property type="entry name" value="GLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-galactopyranose mutase C-terminal" evidence="1">
        <location>
            <begin position="164"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="391" mass="45734" checksum="31A2A2B42FAFA0EB" modified="2007-05-15" version="1" fragment="single">RDREFDLVVVGAGISGCVFASRASRELGMKTLLVDKRDHVGGNCYDFVNAKGFRVSQYGVHLFHTKHARVWEYVNRFSEWTPYEHRVKAAIEREDGEYEHGGRRYRIVGVPPNRDTINALFPEADLKTDEDARRWLDARRSVNENPKNGEESALTRAGAELYEAIFKHYTKKQWDKYPEELDASVLARIPVREDVDDRYFSDPHQALPKHGYTRIFENMIMGDPNITVRLNTDFFEHKDMLRSKARKFVVFTGPIDAWYASQGLPKLEYRSLRFFEEYHEGEDKTKPFFYQPCLQLNYPGPEVEHTRVVEYKHKPNQPREAREHAGTVVFKEYSCDHGEPYYPVPNPANRELYEKYRDMAAKEPGVVFVGRLASYKYFNMDQAFLNALETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4V7</accession>
    <name>A4S4V7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_26544</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420503.1">
        <property type="nucleotide sequence ID" value="XM_001420466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4V7"/>
    <dbReference type="STRING" id="436017.A4S4V7"/>
    <dbReference type="GeneID" id="5004513"/>
    <dbReference type="Gramene" id="ABO98796">
        <property type="protein sequence ID" value="ABO98796"/>
        <property type="gene ID" value="OSTLU_26544"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26544"/>
    <dbReference type="eggNOG" id="KOG0823">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1417290_0_0_1"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16534">
        <property type="entry name" value="RING-HC_RNF5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045103">
        <property type="entry name" value="RNF5/RNF185-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12313">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="73"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO98796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="192" mass="20078" checksum="FF7DB9D6D9C62532" modified="2007-05-15" version="1">MDADASATTSGRATTSARGRGRGDGATTTRDAGEDEGARRRSAGAVRRTSRASFDSDVARGDGEGGTKEKFECNVCFEVAREPVVTPCGHLYCWRCINTWLSVGDNVACPVCKGEMTKDMLIPLYGFGANTARGGAKREGGGAPPLESAAGLATLLGLRSSDELSTEQASQLLLSRYLLAIGTLVIVCLLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5F2</accession>
    <name>A4S5F2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UNC-50 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_39115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-50 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420594.1">
        <property type="nucleotide sequence ID" value="XM_001420557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5F2"/>
    <dbReference type="STRING" id="436017.A4S5F2"/>
    <dbReference type="GeneID" id="5004679"/>
    <dbReference type="Gramene" id="ABO98887">
        <property type="protein sequence ID" value="ABO98887"/>
        <property type="gene ID" value="OSTLU_39115"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39115"/>
    <dbReference type="eggNOG" id="KOG3012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066239_1_2_1"/>
    <dbReference type="OMA" id="YRNFMYR"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007881">
        <property type="entry name" value="UNC-50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12841">
        <property type="entry name" value="PROTEIN UNC-50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12841:SF6">
        <property type="entry name" value="PROTEIN UNC-50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05216">
        <property type="entry name" value="UNC-50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="27989" checksum="71BBB3EC9CEE868B" modified="2007-05-15" version="1">MYVDAARRNASAGHYFRRAFRWRQMDVEYSLWQAASMCVNPKAVYRHTTYRKQTKNQWARDDPTFVVMSCVFVTVAAIGYCAMYGGGGASATARIAARCAVGDYLGLGCVLATVSWYLANTYLRTKHMGGHSHAVEQRVEWMYAFDVHCNAFAPTYVVLYVLQLLLSPLLRRSGYLASACSCVMYAIALAYHNYCVFVGYNALPFLERTEFFLYPAALVLVLAPFAALVAFNPTRFVLWLYFGPGALID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5I3</accession>
    <name>A4S5I3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongin-C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_39373</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420613.1">
        <property type="nucleotide sequence ID" value="XM_001420576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5I3"/>
    <dbReference type="STRING" id="436017.A4S5I3"/>
    <dbReference type="GeneID" id="5004612"/>
    <dbReference type="Gramene" id="ABO98906">
        <property type="protein sequence ID" value="ABO98906"/>
        <property type="gene ID" value="OSTLU_39373"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39373"/>
    <dbReference type="eggNOG" id="KOG3473">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130038_1_1_1"/>
    <dbReference type="OMA" id="GCEDPAM"/>
    <dbReference type="OrthoDB" id="249087at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009867">
        <property type="term" value="P:jasmonic acid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18321">
        <property type="entry name" value="BTB_POZ_EloC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000035">
        <property type="entry name" value="Elongin C transcription elongation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039948">
        <property type="entry name" value="ELC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20648">
        <property type="entry name" value="ELONGIN-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="5">
        <location>
            <begin position="13"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="108" mass="12163" checksum="5DA61CEFD2189A06" modified="2007-05-15" version="1">MSSSTPLDPSTPITLVSSQGDEFVVEYDLLRASGVLKRLFASSEAADFEEQRSKVVKLRDISTAILRKIIDYCEYKRAHEHSSKAPPRFQIDEEDAIELLMAANFLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5I4</accession>
    <name>A4S5I4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420778.1">
        <property type="nucleotide sequence ID" value="XM_001420741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5I4"/>
    <dbReference type="GeneID" id="5004613"/>
    <dbReference type="Gramene" id="ABO99071">
        <property type="protein sequence ID" value="ABO99071"/>
        <property type="gene ID" value="OSTLU_17555"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17555"/>
    <dbReference type="eggNOG" id="ENOG502SRS8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_913341_0_0_1"/>
    <dbReference type="OMA" id="TCESWAV"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="206"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="33788" checksum="9B6D7241B304B71D" modified="2007-05-15" version="1">MATVTATADDGMNYHRMLNLSVVLAEAHAEARELEDEELRACGEEEIRAYYESGGRDVPVGVRERRCEQAGGGREVNDGRASALGDAKERAMLNKHEDAAADYRRHVFKTGIPFRKHGLFPMRDALLMELSRDNSLRAFQKATPGLGRGVFVTCESWAVGDDAAKRGLDLRYFYRERARTGSSEYPELVGVARVGDTGAIGIQTYNLAHGGCIETILDEATAELVKCWRAPCCVTIEMNVKIKKPLPLHHTVKIQVQIKEVQSHGLRIWTTARLTDPSAPLGEDVLATCEAQLCDSGMLNRMREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5S0</accession>
    <name>A4S5S0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_4809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. METTL16/RlmF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420658.1">
        <property type="nucleotide sequence ID" value="XM_001420621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5S0"/>
    <dbReference type="STRING" id="436017.A4S5S0"/>
    <dbReference type="GeneID" id="5004919"/>
    <dbReference type="Gramene" id="ABO98951">
        <property type="protein sequence ID" value="ABO98951"/>
        <property type="gene ID" value="OSTLU_4809"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4809"/>
    <dbReference type="eggNOG" id="KOG2912">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027534_3_0_1"/>
    <dbReference type="OMA" id="MEDHIRL"/>
    <dbReference type="OrthoDB" id="514248at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017182">
        <property type="entry name" value="METTL16/PsiM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393:SF0">
        <property type="entry name" value="RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037350">
        <property type="entry name" value="Mtase_ZK1128_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR037350-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27231" checksum="62346E952E4BC508" modified="2007-05-15" version="1" fragment="single">AVVDFKDWDSTRALTGAILREEYGVEAWTVPRGRLVPTATNRERYLEWLARLRALSAPSGDDASVWVLDIGTGASAIYALLGAAGRGWRFVGTDVCDEALTSARENVRRNPHLESLIEIRDARGEDGARDRVLRGVVRDGETFTFCMCNPPFFETMDEAGRNPNTACGGTATEMVFPGGEEAFVKKIFADSLTMKDSIHWFTTMCGKKSTMTTTRSFLHTHRVPAIRTTELSHGKTSRWCIAWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Z0</accession>
    <name>A4S5Z0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_88841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420855.1">
        <property type="nucleotide sequence ID" value="XM_001420818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Z0"/>
    <dbReference type="GeneID" id="5004894"/>
    <dbReference type="Gramene" id="ABO99148">
        <property type="protein sequence ID" value="ABO99148"/>
        <property type="gene ID" value="OSTLU_88841"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88841"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030320_1_0_1"/>
    <dbReference type="OMA" id="GWHHRHY"/>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="37"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="491" mass="55370" checksum="D78CE48790742281" modified="2007-05-15" version="1">MTTVAEIVDDDARRAGKGATTRRRRATTRVARDDAREATYTAAEVARHARADDCWVIVRGGVYDVTRFVPRHPGGNMIYVKAGGECTALFDSYHPERARATLEKYRIGALRRDAGEREDEDVVEYLKDDLREGEFYADCKAGAAKYFKDNKLDPRVHWEMYAKTLVILTGVVVGHYGSFFAPSASFAAALALAVLHGTCKAEVGVSIQHDANHGAYGNNRTWLHAMQLTLDAVGASSFMWKQQHVAGHHAYTNVEGIDPDIRCSEKDVRRVNEHQPHEPYHRVQHVYLALMYGLLSFKSCFVDDFNAFFSGRIGWVKVMKFTRGEAVAFWGSKLAWAFYYLYLPAKYSHRSIGQLLALWTVTEFVTGWLLAFMFQVAHVVGDVHFFRLNEKNQLNKGWGEAQLMTSADFAHGSKFWTHFSGGLNYQVVHHLFPGVCHVHYPALAPIIKAAADKHGLHYQIYPTFWSALRAHFSHLARVGHEAYVPSLRTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S641</accession>
    <name>A4S641_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Plastid ribosomal protein S21 small ribosomal subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PRPS21</name>
        <name evidence="5" type="ORF">OSTLU_26982</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421025.1">
        <property type="nucleotide sequence ID" value="XM_001420988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S641"/>
    <dbReference type="STRING" id="436017.A4S641"/>
    <dbReference type="GeneID" id="5005055"/>
    <dbReference type="Gramene" id="ABO99318">
        <property type="protein sequence ID" value="ABO99318"/>
        <property type="gene ID" value="OSTLU_26982"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26982"/>
    <dbReference type="eggNOG" id="ENOG502SFBQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2201427_0_0_1"/>
    <dbReference type="OMA" id="VMNSGHI"/>
    <dbReference type="OrthoDB" id="785538at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="Ribosomal_bS21_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="108" mass="12050" checksum="7B61380ECCE23B3D" modified="2007-05-15" version="1">MAFILGGFSHIFAFKGAFQAEVTVGENENAESAIRRFRKAVMSSGHIQETRRRRYFENKQDILKRKQSTPRNKKGGKPKTAAQAIAEKEAAALNPQGQRAGGRARFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S651</accession>
    <name>A4S651_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_41681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420885.1">
        <property type="nucleotide sequence ID" value="XM_001420848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S651"/>
    <dbReference type="STRING" id="436017.A4S651"/>
    <dbReference type="GeneID" id="5005091"/>
    <dbReference type="Gramene" id="ABO99178">
        <property type="protein sequence ID" value="ABO99178"/>
        <property type="gene ID" value="OSTLU_41681"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41681"/>
    <dbReference type="eggNOG" id="KOG4558">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058669_1_2_1"/>
    <dbReference type="OMA" id="NERVMHE"/>
    <dbReference type="OrthoDB" id="497788at2759"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243">
        <property type="entry name" value="AGL049CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE ALR4036 FAMILY FMN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding" evidence="2">
        <location>
            <begin position="7"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="220" mass="24316" checksum="D24E4569BBA5AC89" modified="2007-05-15" version="1">MPSLGVPAWRVAVKAALKKNGKSACAKFAQLATVRASTGAPAVRTVVFRGFGDAFRDDDDDDARDDGDEANALTFCADARSEKIRDIAGDARGEIAWYFPETREQFRVTGTLACATSETAAKDARGEARRRNLWRKMRRGARGQFMWPAPGETRAEVGEGGRDPHDVDEDDARLDDETVGEHFALVALRADRIDHLSLRKNERVMHEIVDGTWTSTRVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4S750</accession>
    <name>A4S750_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</fullName>
            <ecNumber evidence="17">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">OSTLU_43363</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 17">Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="17">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="17">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of complex II composed of eight subunits in plants: four classical SDH subunits SDH1, SDH2, SDH3 and SDH4 (a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.), as well as four subunits unknown in mitochondria from bacteria and heterotrophic eukaryotes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Mitochondrion inner membrane</location>
            <topology evidence="2 17">Peripheral membrane protein</topology>
            <orientation evidence="2 17">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="17"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421210.1">
        <property type="nucleotide sequence ID" value="XM_001421173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S750"/>
    <dbReference type="STRING" id="436017.A4S750"/>
    <dbReference type="GeneID" id="5005398"/>
    <dbReference type="Gramene" id="ABO99503">
        <property type="protein sequence ID" value="ABO99503"/>
        <property type="gene ID" value="OSTLU_43363"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43363"/>
    <dbReference type="eggNOG" id="KOG3049">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_0_2_1"/>
    <dbReference type="OMA" id="DGQYFGP"/>
    <dbReference type="OrthoDB" id="1696654at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045273">
        <property type="term" value="C:respiratory chain complex II (succinate dehydrogenase)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000007">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase iron-sulfur subunit SdhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050573">
        <property type="entry name" value="SDH/FRD_Iron-Sulfur"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004616">
        <property type="entry name" value="PRK05950.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921:SF29">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13534">
        <property type="entry name" value="Fer4_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="15 17" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7 17" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 17" id="KW-0408">Iron</keyword>
    <keyword evidence="14 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="19">
        <location>
            <begin position="26"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ABO99503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="28721" checksum="188BEED131F1A9F7" modified="2007-05-15" version="1">MRASASASASTSATTTTTTTTTTNVQQFRVYRWDPDSGDEPKYKTYDVDTNDCGPMMLDVLFKIKDEQDQTLSFRRSCREGICGSCAMNINGRNGLACLTKVEKTEKGAQTIAPLPHMFVVRDLVVDMANFYAQYKSIEPFLKTKSDAPANGAERLQTKEDRAKLDGLYECILCACCSTSCPSYWWNSDKYLGPAVLLQAYRWIIDSRDEFTEERLANVNDAFKLYRCHTIMNCSKVCPKGLNPALKIAKIKQMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S767</accession>
    <name>A4S767_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_89084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421401.1">
        <property type="nucleotide sequence ID" value="XM_001421364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S767"/>
    <dbReference type="GeneID" id="5005405"/>
    <dbReference type="Gramene" id="ABO99694">
        <property type="protein sequence ID" value="ABO99694"/>
        <property type="gene ID" value="OSTLU_89084"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89084"/>
    <dbReference type="eggNOG" id="ENOG502S5TX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078630_0_0_1"/>
    <dbReference type="OMA" id="PANTYMF"/>
    <dbReference type="OrthoDB" id="533393at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36974:SF1">
        <property type="entry name" value="DOXX FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36974">
        <property type="entry name" value="MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="27386" checksum="C122786E9C75FD1F" modified="2007-05-15" version="1">MRPSVAVVARAAAFARVARPRASRARRPASSTRRPRATRVSASPELEPRDVAPWTAPGYRGARVSALDERAQTACVLAVWAAILLGTYECCEVVGPATRALAPELAAWSARSWPLIGLTYIAAGAAHFAVHDGFTSMMPHKGAWGFWNLPGSASFHVNWTGVAEILGGFGVVLGSLPFGLTPDFCESWLTPASAAGLFLLTIVVTPANTYMWTHNSPGPLPPNADESMQVLPWQGHLARAALQIFLLTMLHGLIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7D5</accession>
    <name>A4S7D5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">G8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_27441</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421255.1">
        <property type="nucleotide sequence ID" value="XM_001421218.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S7D5"/>
    <dbReference type="GeneID" id="5005367"/>
    <dbReference type="Gramene" id="ABO99548">
        <property type="protein sequence ID" value="ABO99548"/>
        <property type="gene ID" value="OSTLU_27441"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27441"/>
    <dbReference type="eggNOG" id="ENOG502QUGT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_225505_0_0_1"/>
    <dbReference type="OrthoDB" id="530609at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055401">
        <property type="entry name" value="CEMIP_beta-hel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052387">
        <property type="entry name" value="Fibrocystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019316">
        <property type="entry name" value="G8_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769:SF2">
        <property type="entry name" value="FIBROCYSTIN-L ISOFORM 2 PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769">
        <property type="entry name" value="POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24606">
        <property type="entry name" value="CEMIP_beta-hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10162">
        <property type="entry name" value="G8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01225">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51484">
        <property type="entry name" value="G8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="G8" evidence="8">
        <location>
            <begin position="1489"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="domain" description="G8" evidence="8">
        <location>
            <begin position="2426"/>
            <end position="2553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1364"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2122"/>
            <end position="2146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1385"/>
            <end position="1396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="3191" mass="352143" checksum="7974D2071CF788E3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7S4</accession>
    <name>A4S7S4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421505.1">
        <property type="nucleotide sequence ID" value="XM_001421468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7S4"/>
    <dbReference type="GeneID" id="5005480"/>
    <dbReference type="Gramene" id="ABO99798">
        <property type="protein sequence ID" value="ABO99798"/>
        <property type="gene ID" value="OSTLU_27600"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27600"/>
    <dbReference type="HOGENOM" id="CLU_172791_0_0_1"/>
    <dbReference type="OMA" id="ARETQTF"/>
    <dbReference type="OrthoDB" id="10541284at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="93" mass="10810" checksum="C8D090900157E29B" modified="2007-05-15" version="1">MGKLDGLSELQRRKRATLARIEASARDGETLRRRVKELEQRVARDRERVKAYDKVIQEGESSLDRILESSEFLLSALARETQTFEDDEDDVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8L1</accession>
    <name>A4S8L1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421785.1">
        <property type="nucleotide sequence ID" value="XM_001421748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8L1"/>
    <dbReference type="GeneID" id="5005751"/>
    <dbReference type="Gramene" id="ABP00079">
        <property type="protein sequence ID" value="ABP00079"/>
        <property type="gene ID" value="OSTLU_93811"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93811"/>
    <dbReference type="HOGENOM" id="CLU_627606_0_0_1"/>
    <dbReference type="OMA" id="MAMAYVF"/>
    <dbReference type="OrthoDB" id="497760at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="437" mass="47456" checksum="8595CC577DD6AC01" modified="2007-05-15" version="1">MRAFAARALAPRAIDRGHRARLKRASSRVEASAGRRGARSFADARAAVGCDASPRARPAASRARRERPSTRRRATASSEDPAARDGEDARPELEDTIAPLSDALYPRALDAVPTFFGRLNPLTAVLLFYTGAMLRESREAPIIGAQWLLLVVLPTFGALYALRRWWYENKTSPRHEGEHRPFAFNRACRSAWLDFHVGYMLLVPAGAYGGEGSSWWVMTAPILMALRWLGGRRGKIFKTARRACVVVFGVVGLATLLLSTSTTLTKALGALRGGGAVGFILGPFAMAMAYVFYVAPACLLPRAIARAWTNTLDDAPIAETSEEDKNKTPEQIAKEKRKKRVNLIVGFVAFGATLATGSDLPLLILFAFQLLKVDPEDFVNAIINKGSPERMEMEQAIADKFAGVFADTKTEASKTDADDASADDARDPTTTTTTPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8N9</accession>
    <name>A4S8N9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27916</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421658.1">
        <property type="nucleotide sequence ID" value="XM_001421621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8N9"/>
    <dbReference type="STRING" id="436017.A4S8N9"/>
    <dbReference type="GeneID" id="5005799"/>
    <dbReference type="Gramene" id="ABO99951">
        <property type="protein sequence ID" value="ABO99951"/>
        <property type="gene ID" value="OSTLU_27916"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27916"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034043_0_0_1"/>
    <dbReference type="OMA" id="RTCTWSM"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="440"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="501"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="577" mass="63364" checksum="6363C155C94C1A9A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8W6</accession>
    <name>A4S8W6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421960.1">
        <property type="nucleotide sequence ID" value="XM_001421923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8W6"/>
    <dbReference type="STRING" id="436017.A4S8W6"/>
    <dbReference type="GeneID" id="5006000"/>
    <dbReference type="Gramene" id="ABP00254">
        <property type="protein sequence ID" value="ABP00254"/>
        <property type="gene ID" value="OSTLU_25645"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25645"/>
    <dbReference type="eggNOG" id="ENOG502S6IW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_429867_0_0_1"/>
    <dbReference type="OrthoDB" id="528882at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="637" mass="67955" checksum="CD0C41F2ADEC4D11" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S902</accession>
    <name>A4S902_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421847.1">
        <property type="nucleotide sequence ID" value="XM_001421810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S902"/>
    <dbReference type="GeneID" id="5006021"/>
    <dbReference type="Gramene" id="ABP00141">
        <property type="protein sequence ID" value="ABP00141"/>
        <property type="gene ID" value="OSTLU_25655"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25655"/>
    <dbReference type="eggNOG" id="KOG2761">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_535718_0_0_1"/>
    <dbReference type="OMA" id="WRMRTIP"/>
    <dbReference type="OrthoDB" id="495907at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF39">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="2">
        <location>
            <begin position="208"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="513" mass="57685" checksum="01618CEC49114483" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S913</accession>
    <name>A4S913_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_8514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421985.1">
        <property type="nucleotide sequence ID" value="XM_001421948.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S913"/>
    <dbReference type="STRING" id="436017.A4S913"/>
    <dbReference type="GeneID" id="5005883"/>
    <dbReference type="Gramene" id="ABP00279">
        <property type="protein sequence ID" value="ABP00279"/>
        <property type="gene ID" value="OSTLU_8514"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8514"/>
    <dbReference type="eggNOG" id="KOG4548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099204_0_0_1"/>
    <dbReference type="OrthoDB" id="498201at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04661">
        <property type="entry name" value="NUDIX_MRP_L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040008">
        <property type="entry name" value="Ribosomal_mL46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033650">
        <property type="entry name" value="Ribosomal_mL46_NUDIX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="132" mass="15229" checksum="0D588F613616127B" modified="2007-05-15" version="1" fragment="single">FEPAPRETEADRTGDRSTLHRKLPEFLFLVVKEKDGKWGFPKSKHDDGETMRQTAERSLKAFAGDSLECWVVGNAPQGHYETADGTTFYYRGSYIEGELELQDGYVEHAWVTKEELGEYFDADHHDLLKRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9J7</accession>
    <name>A4S9J7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422079.1">
        <property type="nucleotide sequence ID" value="XM_001422042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9J7"/>
    <dbReference type="STRING" id="436017.A4S9J7"/>
    <dbReference type="GeneID" id="5006240"/>
    <dbReference type="Gramene" id="ABP00396">
        <property type="protein sequence ID" value="ABP00396"/>
        <property type="gene ID" value="OSTLU_28225"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28225"/>
    <dbReference type="eggNOG" id="ENOG502QU37">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068991_0_0_1"/>
    <dbReference type="OMA" id="VRPAKIW"/>
    <dbReference type="OrthoDB" id="9970474at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039343">
        <property type="entry name" value="NDX1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35467">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35467:SF2">
        <property type="entry name" value="PROTEIN NEOXANTHIN-DEFICIENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="27204" checksum="E7C894D587A6A98C" modified="2007-05-15" version="1">MGYKDPAPWTFTGKALYQLALVRAEDARAHVPSDLRLVEFAGHTLGGLYVARYDESPCGKLDEVVVLGGLVWNPPTSCAWASRVYVDSAEARAHGIRTCGLPSRVAAFREETDASSKQRGWTNKTRWWHGTKRGKGDASTGAVSIVEGKTKVCELALPSEPKLKGPRISMFLPSFSGRTKSIPDLLKYSLRMNANVRLSAPIKVKPSDEHGAVTNILKGKPLLCIAFDNMRMDVGAPQKVKVARARDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9P1</accession>
    <name>A4S9P1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="1">2.7.1.68</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_18669</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.68" evidence="1"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422101.1">
        <property type="nucleotide sequence ID" value="XM_001422064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9P1"/>
    <dbReference type="STRING" id="436017.A4S9P1"/>
    <dbReference type="GeneID" id="5006159"/>
    <dbReference type="Gramene" id="ABP00418">
        <property type="protein sequence ID" value="ABP00418"/>
        <property type="gene ID" value="OSTLU_18669"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18669"/>
    <dbReference type="eggNOG" id="KOG0229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_614447_0_0_1"/>
    <dbReference type="OMA" id="TMYSCSP"/>
    <dbReference type="OrthoDB" id="158357at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00139">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="63"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="483" mass="54535" checksum="B4C22319B2F9BC62" modified="2007-05-15" version="1">MKRLNVGRASRRTKQMRRLWTKVHRGNRLGTADGDVLTNHLGLCLQLAFTAQSRGASGDASGGGEAAEETVKREVYAVKKMEMANGELLPNFSYTVEAPKKFEELRLLWGMDAHSYRSAFAIPDVRTVCDDVQTQNGEIRGNMRTETGKLEATSTSLRVISQALASGKSRSWFFCSEDGTLLVKTCNVAEKRTLLKMLPEYTEYVRENSTVSMLPQFYGLYTIKFNGTRPLSFIVMNYWFASTKIIQKRFDLKGSTFGRRASARELAKGSVCIYKDNDFREEDAVHTRHSQNICDVLKKDSEFLAKRNLIDYSLVFGEYQAVTPTDIFEANKAFEEFETDHADWKDQRAAAVAVAESDEGKSDTNSLADSDAVSEKSEEFLMLEKASMFTPFLHDVARLNQLRMVNKPKGAVFCGIIDILTEWGPRKKLERFFTSQICCGRDVSCQRPDVYAKRFSAFMNQNVFLPAIERATADDVGFTLAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9U7</accession>
    <name>A4S9U7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422232.1">
        <property type="nucleotide sequence ID" value="XM_001422195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9U7"/>
    <dbReference type="GeneID" id="5006188"/>
    <dbReference type="Gramene" id="ABP00549">
        <property type="protein sequence ID" value="ABP00549"/>
        <property type="gene ID" value="OSTLU_28320"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28320"/>
    <dbReference type="HOGENOM" id="CLU_183254_0_0_1"/>
    <dbReference type="OMA" id="DYHGVDK"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="10307" checksum="0A961B088D35718D" modified="2007-05-15" version="1">MAGKIQRQKLAKGGSRGRYGVSGLSAFRSKSRPARRAPIARNRGADYQKFVELRAKVDALSAEEAKGTLDKATAKELKNLRAKLTLKERKHGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAD3</accession>
    <name>A4SAD3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial-processing peptidase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_51888</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422415.1">
        <property type="nucleotide sequence ID" value="XM_001422378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAD3"/>
    <dbReference type="STRING" id="436017.A4SAD3"/>
    <dbReference type="GeneID" id="5006425"/>
    <dbReference type="Gramene" id="ABP00732">
        <property type="protein sequence ID" value="ABP00732"/>
        <property type="gene ID" value="OSTLU_51888"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51888"/>
    <dbReference type="eggNOG" id="KOG2067">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_5_1_1"/>
    <dbReference type="OMA" id="LKYHHSP"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF49">
        <property type="entry name" value="MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="4">
        <location>
            <begin position="32"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="5">
        <location>
            <begin position="184"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="47476" checksum="FFFFF03DDE38563D" modified="2007-05-15" version="1">MSETHAHDAPTEARATAPPTTSVTVLANGATIASENTPGATLACGAYVDCGSAREDAPWKRGFSHALERAAFRATKHRSGFRVTRECETIGANLSASASREQFCFAADALKTRAAETVELLLDCALNPALENHEIERVVENLKTEVKELNENPQALLMEATHATAYAGGLGHALVAPSGDLSHITGDALREFVRENFTAPRVVLAASGCEHDELVRIAEPMLATLPSGEGSPETPTTYVGGDFRQKSDSPITSIVLGFEFKGGWRDTKASTAMTVLTMLLGGGGSFSAGGPGKGMYSRLYTRVLNRYSWAQNCTAFHSIFNDTGIVGISAMANSAHTGDMVKVMAGELQAVAASGGVSPQELERAKNATVSSILMNLESKAVVAEDIGRQMLTYKYRKSAADFIAEVRAVSAQDVQKVASDLLASAPTVAMTGELHAAPRYEDIKAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAH9</accession>
    <name>A4SAH9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cornichon-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_9005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422392.1">
        <property type="nucleotide sequence ID" value="XM_001422355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAH9"/>
    <dbReference type="STRING" id="436017.A4SAH9"/>
    <dbReference type="GeneID" id="5006493"/>
    <dbReference type="KEGG" id="olu:OSTLU_9005"/>
    <dbReference type="eggNOG" id="KOG2729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112942_3_1_1"/>
    <dbReference type="OMA" id="YTVICVD"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672273" description="Cornichon-like protein" evidence="6">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="12787" checksum="B82D4421B2CDF101" modified="2007-05-15" version="1" fragment="single">LYGFALFVNLYVLAALDDLQADLVNPHDASRRINRLVNHEIAAHACASALMLCGGHYALFAANAPMMYWEHKRREARTLRIDATEIFARADSERKIRTRKLAFLGVVELIVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAJ8</accession>
    <name>A4SAJ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_5174</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422402.1">
        <property type="nucleotide sequence ID" value="XM_001422365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAJ8"/>
    <dbReference type="STRING" id="436017.A4SAJ8"/>
    <dbReference type="GeneID" id="5006460"/>
    <dbReference type="Gramene" id="ABP00719">
        <property type="protein sequence ID" value="ABP00719"/>
        <property type="gene ID" value="OSTLU_5174"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5174"/>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_18_15_1"/>
    <dbReference type="OMA" id="QEICEYS"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="4">
        <location>
            <begin position="131"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="242" mass="26835" checksum="39AF8E1E6FD07DDE" modified="2007-05-15" version="1" fragment="single">AKETKRLDLSGLGLREIPGEARELSDLIELQVSNNLLYEIPGDLIARFEKLERLGCAGNRLRALPREVGGLKSLRGIWAHGNLLNRVPEEIGNCESLRNLVLGGNRLRELPKTLGNLKNLEELSAPGNQLTSLPDLGSMPLLREIDLHGNAIEALPEDMSGLKALETLSLQGNKLKTIPKSAATLRRLRALNLAENVVERLPSEISEMTMLTSLWLYSNALKELPETMKKMPSLRQLWIEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAM3</accession>
    <name>A4SAM3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Brix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422635.1">
        <property type="nucleotide sequence ID" value="XM_001422598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAM3"/>
    <dbReference type="STRING" id="436017.A4SAM3"/>
    <dbReference type="GeneID" id="5006516"/>
    <dbReference type="Gramene" id="ABP00952">
        <property type="protein sequence ID" value="ABP00952"/>
        <property type="gene ID" value="OSTLU_29310"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29310"/>
    <dbReference type="eggNOG" id="KOG2781">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040063_2_0_1"/>
    <dbReference type="OMA" id="IGTMSEQ"/>
    <dbReference type="OrthoDB" id="10253204at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000001">
        <property type="entry name" value="IMP4, U3 small nucleolar ribonucleoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF2">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="1">
        <location>
            <begin position="85"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="291" mass="33550" checksum="18E9086884661912" modified="2007-05-15" version="1">MLRRTARLRREFVYRKSLEGKERELYEKKRTIRQCLEDGKAIPTELRKEEARLREEVHAEDAKTASYGARGVIDDEYAKAAEREPRVLLTTSRDPSSRLQQFAKELKLLFPTSQRINRGSQILPDLVDLCRNGGFTDLVMVHEHRGEPDGLVISHLPFGPTCYFGLSNTVMRHDIKDQDIGHVSEVFPHLILENFTSPLGKRTATVLKHLFPEPKAKSKRVVTFANDADYISLRHHMYEMPKGAKSVALTEIGPRFEMRLYQIKLGTVEMDDCDIEWSLRPFMRSGKKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAY5</accession>
    <name>A4SAY5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Small nuclear ribonucleoprotein E</fullName>
            <shortName evidence="12">snRNP-E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Sm protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_29422</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422520.1">
        <property type="nucleotide sequence ID" value="XM_001422483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAY5"/>
    <dbReference type="STRING" id="436017.A4SAY5"/>
    <dbReference type="GeneID" id="5006742"/>
    <dbReference type="Gramene" id="ABP00837">
        <property type="protein sequence ID" value="ABP00837"/>
        <property type="gene ID" value="OSTLU_29422"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29422"/>
    <dbReference type="eggNOG" id="KOG1774">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125186_1_0_1"/>
    <dbReference type="OMA" id="VPPINCI"/>
    <dbReference type="OrthoDB" id="25620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01718">
        <property type="entry name" value="Sm_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000013">
        <property type="entry name" value="Small nuclear ribonucleoprotein E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027078">
        <property type="entry name" value="snRNP-E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11193">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 12" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="13">
        <location>
            <begin position="13"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00058057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABP00837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="87" mass="10133" checksum="166C5B70F99F418A" modified="2007-05-15" version="1">MATKVQRIMTQPINLIFRFLQTKARVQIWMYENPDTCVEGRIVGFDEYMNLVLDDAEEVTEKKSRRVGVGRILLKGDNITLMRNVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB68</accession>
    <name>A4SB68_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29504</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422564.1">
        <property type="nucleotide sequence ID" value="XM_001422527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB68"/>
    <dbReference type="STRING" id="436017.A4SB68"/>
    <dbReference type="GeneID" id="5006622"/>
    <dbReference type="Gramene" id="ABP00881">
        <property type="protein sequence ID" value="ABP00881"/>
        <property type="gene ID" value="OSTLU_29504"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29504"/>
    <dbReference type="eggNOG" id="ENOG502S72G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_800097_0_0_1"/>
    <dbReference type="OMA" id="IREIMRH"/>
    <dbReference type="OrthoDB" id="550454at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="159"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="365" mass="38732" checksum="C4C64BB839FB99DF" modified="2007-05-15" version="1">MSGDGFFTFTDADPSQWLPKGIVDEREEHDAGAYASFALPQGSASRSASDDNSRGSFDSFGVKSKVLGSVLYDDEGLIPLGLGGHAYVDKSTSPKSTASPTAAFVADAEFGAAAASGSRLRGPSGPRRAGQGVEEEEQQVASIEVMANGGLRLRVTLLAAGFVIGASGASIREIMRHTGSTIQSWTQQPEMGVYHRPCRVFCIQGLPESVMAASNIIHEAVERYKELCEGKRRGEFVQRLQYIRGVEFSYQPPPKNAVPNAASVNGATRQGTNPLLMPRQPTNAANETMRLLAAAQAQRAAMQHYQNLATQSYAAGLAAGAKMGHVPAISAMSAMPDSENPFAAAQMPNPSDFFTAFSAQTRPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBE2</accession>
    <name>A4SBE2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coenzyme Q-binding protein COQ10 START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_19114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422761.1">
        <property type="nucleotide sequence ID" value="XM_001422724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBE2"/>
    <dbReference type="STRING" id="436017.A4SBE2"/>
    <dbReference type="GeneID" id="5006659"/>
    <dbReference type="Gramene" id="ABP01078">
        <property type="protein sequence ID" value="ABP01078"/>
        <property type="gene ID" value="OSTLU_19114"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19114"/>
    <dbReference type="eggNOG" id="KOG3177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102371_0_0_1"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="5">
        <location>
            <begin position="77"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP01078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="26040" checksum="7F1C5103D91D4CA3" modified="2007-05-15" version="1">MSRALARRAREAATRATRAVGPTRATPGATLGRAREVATRGDDGDGRNGDGDGDEGARRRFSARRIVKGIARDALCDAVADVDSYAAFVPFCAGARRTPRERWGREREREALARGEEYFEADLEIGFKLFNEKYTSAVTCARPERVTATSVSSGLFRSMTTTWKFSPLDDDEDEDPVTGLPAEGVIVDFEIDFEVKDPMHAAAVSVVFDDVARSQIQAFEKRCRQLALRGGLERDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBL4</accession>
    <name>A4SBL4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ARID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422883.1">
        <property type="nucleotide sequence ID" value="XM_001422846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBL4"/>
    <dbReference type="STRING" id="436017.A4SBL4"/>
    <dbReference type="GeneID" id="5006852"/>
    <dbReference type="Gramene" id="ABP01242">
        <property type="protein sequence ID" value="ABP01242"/>
        <property type="gene ID" value="OSTLU_94134"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94134"/>
    <dbReference type="HOGENOM" id="CLU_073694_0_0_1"/>
    <dbReference type="OMA" id="CKICHAN"/>
    <dbReference type="OrthoDB" id="498240at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042293">
        <property type="entry name" value="ARID4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46694">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46694:SF1">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="2">
        <location>
            <begin position="38"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="281" mass="31437" checksum="431136C0D1F5AE22" modified="2007-05-15" version="1" fragment="single">VKTPTGRDDGDDGFCPAWTRRGRGTIASAAWRRPALAACSLEDFTFDLMRFHQERGRDWEQCWANLDRVVGRTGAPLDCLHLYRQVCSLGGFASRTSAKERIKAAEIFRNMFNHYENHTMTDCGNRMLTAYENYFLEYEAAHEEDLTRGTCGNCGGGIQTSIGTVADLLHECVGCERMFHGRCQPPEVFPPIHGEGKNAGCSTRIVCFECRAGGAYAASTKLLRDEREDADSYQTRLYECVARRGRRYKSSYVRPTRAMDEGAKPPSPTGNDPDDGSKMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQQ9</accession>
    <name>A4RQQ9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415429.1">
        <property type="nucleotide sequence ID" value="XM_001415392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQQ9"/>
    <dbReference type="STRING" id="436017.A4RQQ9"/>
    <dbReference type="GeneID" id="4999473"/>
    <dbReference type="Gramene" id="ABO93721">
        <property type="protein sequence ID" value="ABO93721"/>
        <property type="gene ID" value="OSTLU_92090"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92090"/>
    <dbReference type="HOGENOM" id="CLU_617363_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="444" mass="52409" checksum="9C2BA1CB611A4456" modified="2007-05-15" version="1">MHDTASRKPTSRVLDRAPCESAESLFENLCQNWAKRADELARFERELCATREAVRLSSDGSDLDMVEKDTRPCSRACGEDTRDTPARPRRTESTFSAEPPAKRRAKQRIKSFVTEESDEDEDTEVSLRELLSRAIEESVAVRRRRVEKETERRKIVDTARVRRDAGRTIARSLKRWHTRRMRTICVVQSICRRWLALRRVRAVRDRRERLTRMFWIWRSTLIRARRRRACVRIQSSWRGYATRRALREDKGRRERVKRCVEEIVKRYIQRHERAKRACAAQRIQRAWRAFIRFSTLRRMNAATLQIQRVWRGTRTRRAVRSYRESTVRRNAVEFDLESADEDDFMDDDDDENAALRDVFDSVTCSTAERIAESTERARATSSRAPAASARQSDDSASTASREHYNRRHTRHIREQSKRRRREALQTSSTARFAAFRSNAARSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR04</accession>
    <name>A4RR04_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S15a, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS15a</name>
        <name evidence="5" type="ORF">OSTLU_40222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415819.1">
        <property type="nucleotide sequence ID" value="XM_001415782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR04"/>
    <dbReference type="STRING" id="436017.A4RR04"/>
    <dbReference type="GeneID" id="4999422"/>
    <dbReference type="Gramene" id="ABO94111">
        <property type="protein sequence ID" value="ABO94111"/>
        <property type="gene ID" value="OSTLU_40222"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40222"/>
    <dbReference type="eggNOG" id="KOG1754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098428_1_1_1"/>
    <dbReference type="OMA" id="EWANNIL"/>
    <dbReference type="OrthoDB" id="523101at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_A">
        <property type="entry name" value="Ribosomal_uS8_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="130" mass="14956" checksum="32B0FCB7A9FA69E2" modified="2007-05-15" version="1">MVRISVLNDTLKSMYNAEKRGKRQVLVRPVSKVVIKFLQVMQKHGYINEFEFIDDHRAGKIVVELNGRINKCGVISPRYDLSHHDLEDWVGRLLPSRLFGVIVLTTSSGIMDHEEARRKKVGGKVLGYFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR42</accession>
    <name>A4RR42_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
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                <person name="Dupont C."/>
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</entry>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415933.1">
        <property type="nucleotide sequence ID" value="XM_001415896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRN5"/>
    <dbReference type="STRING" id="436017.A4RRN5"/>
    <dbReference type="GeneID" id="4999461"/>
    <dbReference type="Gramene" id="ABO94225">
        <property type="protein sequence ID" value="ABO94225"/>
        <property type="gene ID" value="OSTLU_92186"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92186"/>
    <dbReference type="eggNOG" id="KOG3710">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_837703_0_0_1"/>
    <dbReference type="OMA" id="PRYCLTT"/>
    <dbReference type="OrthoDB" id="76265at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="5">
        <location>
            <begin position="28"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="35459" checksum="705E0D496F349E55" modified="2007-05-15" version="1">MSRRFTGAYAAIARALVAGDAKARLARHGYVVLDDAFDVARARALKDEFNALRRRGAFVANASLFAREGVVALAKPHVYECEVHRLSKEDAASAPLVNELAKETSVMEALNEAFGALGGGALDRTSTKLQVNEGAGGCFPLHFDSDASLDSRRVTMCAYLDEDWCEARDGGALALYPFPRGRVTIAPKAGRVVIFSSEFGLHRVMPAMRERFMFTVWYFAKEMRAPMKAKPPGVTAEAQMTALLDPALRKHLGKIVLADEWAKSIREAHGESEGVEAALKTHWDEVALISRVLSNNYPLGLELIAKEMERGDGAFDAGVDWFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSD2</accession>
    <name>A4RSD2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_30295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416510.1">
        <property type="nucleotide sequence ID" value="XM_001416473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSD2"/>
    <dbReference type="STRING" id="436017.A4RSD2"/>
    <dbReference type="GeneID" id="5000348"/>
    <dbReference type="Gramene" id="ABO94803">
        <property type="protein sequence ID" value="ABO94803"/>
        <property type="gene ID" value="OSTLU_30295"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30295"/>
    <dbReference type="HOGENOM" id="CLU_957760_0_0_1"/>
    <dbReference type="OMA" id="REMGHFE"/>
    <dbReference type="OrthoDB" id="273070at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039136">
        <property type="entry name" value="NUFIP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309:SF0">
        <property type="entry name" value="FMR1-INTERACTING PROTEIN NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309">
        <property type="entry name" value="NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="291" mass="32471" checksum="39C624A293EE91CE" modified="2007-05-15" version="1">MKSASIADANAAAMMAEVKVVDPSSLPEDVRRYREERAKYWPSDRNVRAKTEAGEEEERARAARRERLREILAKQREMGHFEASQEIGEEEGGVAAPAALDGKGVEARAADGSKVCRFWLQGGCRKGSACDFKHESAPNKDQKCRFFARGRCKAGARCPFKHEVTERKSSAADGGGNPQTLLKKLLDKEIKRDEQRLLQLFRFFVNNDFFTGTKGVDEPLWMFPWADSGKKVIDRRAALASLSPVDDEDDEDEVAPPPVAPADSVEEKRHQDRPDMGFFAAYDSDNDSNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSN3</accession>
    <name>A4RSN3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_8348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416464.1">
        <property type="nucleotide sequence ID" value="XM_001416427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSN3"/>
    <dbReference type="STRING" id="436017.A4RSN3"/>
    <dbReference type="GeneID" id="5000534"/>
    <dbReference type="KEGG" id="olu:OSTLU_8348"/>
    <dbReference type="eggNOG" id="KOG0291">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_18_1"/>
    <dbReference type="OrthoDB" id="541653at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="148" mass="16109" checksum="F515A5AEF3661F03" modified="2007-05-15" version="1" fragment="single">LSDDGETLITGTHSGVVNVWSIQTSSCVATFHHHEALVSAVECLRSGGGFLSASFDGTILMWSFTTGQLLEVLSGHSAIISSLDFCMTTTMVSGSWDGTVRLWDMSHREFACEVIPHSRDVIAVAIRRDDKQLAVSTSGQKIAFWKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP5</accession>
    <name>A4RSP5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_14296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416453.1">
        <property type="nucleotide sequence ID" value="XM_001416416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP5"/>
    <dbReference type="STRING" id="436017.A4RSP5"/>
    <dbReference type="GeneID" id="5000302"/>
    <dbReference type="Gramene" id="ABO94746">
        <property type="protein sequence ID" value="ABO94746"/>
        <property type="gene ID" value="OSTLU_14296"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14296"/>
    <dbReference type="HOGENOM" id="CLU_730341_0_0_1"/>
    <dbReference type="OrthoDB" id="9158at13792"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="43729" checksum="B7C1EBE46B84682A" modified="2007-05-15" version="1">MEKDRQSAWLDELYFEHSATREGKHVQRSSTGQAITKDLHKFSNALLNALRVRQILQFNQELLILTEKLAEKTNEGDLIEALNAYEDLLRLHKSRSNVRSKTDIDIESSLTSVHCFVRNATSSYCQSALVVDDLVNVLHIVDKLVRIELHHVVEDAVTTSIRETMVARYENAQNMNLDRGQIPARVSMLPLNTLYETIRSFLSQLQTYSKERKPSEAVSFVFAAIVGTWSSLVEKFLVEYDDHLKTCVLDNLTIKFDNLVQLDTAVEDIVLVNRICKAQHVIFVKFPLTMEYDNPPLHTVVSQDCREVFPVLHTLAEYYVKLEEKHFKYKAGFCVDRATYHRNNFTHGEQVSHRFLRTNDESVSESECRGYCRGILDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSV0</accession>
    <name>A4RSV0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aconitate hydratase B</fullName>
            <ecNumber evidence="6">4.2.1.3</ecNumber>
            <ecNumber evidence="7">4.2.1.99</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">(2R,3S)-2-methylisocitrate dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">2-methyl-cis-aconitate hydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Iron-responsive protein-like</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">RNA-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="primary">AcnB</name>
        <name evidence="25" type="ORF">OSTLU_119573</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="6"/>
    <dbReference type="EC" id="4.2.1.99" evidence="7"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416185.1">
        <property type="nucleotide sequence ID" value="XM_001416148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSV0"/>
    <dbReference type="STRING" id="436017.A4RSV0"/>
    <dbReference type="GeneID" id="5000445"/>
    <dbReference type="Gramene" id="ABO94478">
        <property type="protein sequence ID" value="ABO94478"/>
        <property type="gene ID" value="OSTLU_119573"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119573"/>
    <dbReference type="eggNOG" id="KOG0454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016536_0_0_1"/>
    <dbReference type="OMA" id="PLHAKAM"/>
    <dbReference type="OrthoDB" id="419183at2759"/>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01581">
        <property type="entry name" value="AcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01576">
        <property type="entry name" value="AcnB_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.310:FF:000001">
        <property type="entry name" value="Aconitate hydratase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000004">
        <property type="entry name" value="Aconitate hydratase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000008">
        <property type="entry name" value="Aconitate hydratase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.310">
        <property type="entry name" value="Aconitate B, HEAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004406">
        <property type="entry name" value="Aconitase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015933">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036288">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015929">
        <property type="entry name" value="Aconitase_B_swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00117">
        <property type="entry name" value="acnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006690">
        <property type="entry name" value="PRK09238.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF4">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06434">
        <property type="entry name" value="Aconitase_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11791">
        <property type="entry name" value="Aconitase_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74778">
        <property type="entry name" value="Aconitase B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase B HEAT-like" evidence="24">
        <location>
            <begin position="73"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase B swivel" evidence="23">
        <location>
            <begin position="237"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="22">
        <location>
            <begin position="533"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00019379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00031977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00032417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF06434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF11791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ABO94478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="918" mass="99532" checksum="3B8F0FD390653402" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSX6</accession>
    <name>A4RSX6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved protein probably involved in Fe-S center assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SUFE</name>
        <name evidence="3" type="ORF">OSTLU_95454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416417.1">
        <property type="nucleotide sequence ID" value="XM_001416380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSX6"/>
    <dbReference type="STRING" id="436017.A4RSX6"/>
    <dbReference type="GeneID" id="5000436"/>
    <dbReference type="Gramene" id="ABO94710">
        <property type="protein sequence ID" value="ABO94710"/>
        <property type="gene ID" value="OSTLU_95454"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_95454"/>
    <dbReference type="HOGENOM" id="CLU_2429981_0_0_1"/>
    <dbReference type="OMA" id="HTTEWPT"/>
    <dbReference type="OrthoDB" id="495661at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597:SF5">
        <property type="entry name" value="SUFE-LIKE PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597">
        <property type="entry name" value="SULFUR ACCEPTOR PROTEIN CSDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S metabolism associated" evidence="2">
        <location>
            <begin position="20"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="109" mass="11991" checksum="FF19E41CE4F77A96" modified="2007-05-15" version="1">MIVTRYVLHTTEWPTLILLQVPGCVSQVWIVPSFRGGLVYYEAESDSQLTKGLAALLIKGLSGNSPQDIAEVKPEFLGELGLKTALTPSRTNGLLNMLNLMQMQARSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSZ8</accession>
    <name>A4RSZ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YchF</name>
        <name evidence="8" type="ORF">OSTLU_119525</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416160.1">
        <property type="nucleotide sequence ID" value="XM_001416123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSZ8"/>
    <dbReference type="STRING" id="436017.A4RSZ8"/>
    <dbReference type="GeneID" id="5000127"/>
    <dbReference type="Gramene" id="ABO94453">
        <property type="protein sequence ID" value="ABO94453"/>
        <property type="gene ID" value="OSTLU_119525"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119525"/>
    <dbReference type="eggNOG" id="KOG1491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018395_0_1_1"/>
    <dbReference type="OMA" id="ARQWTIR"/>
    <dbReference type="OrthoDB" id="424823at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF18">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="51"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="7">
        <location>
            <begin position="334"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="419" mass="45577" checksum="66BC3A6230E0B4F7" modified="2007-05-15" version="1">MLAQKFAHTTLRSSVALRGDGWFLSGKLTLRTKSFGPARSRTLHSNCRASLKTGIVGLPNVGKSTLFNALVENSRAQAANFPFCTIEPNFGTVPVLDGRLDVLARISGTKNIVPTAVEIVDIAGLVEGASEGQGLGNKFLANIRECDAIIHVVRCFDDDNIVHVNGSVDPKRDAAIINSELALSDMSQIQKRIDKVRKSKGKVHIDGQTAETEIEILSNILTQLEDGKQVRQLKLNEDELFVIKELNLLTAKPCIYAANLPEGDLPTNGATNVHFQALSKLATDSEAGLCAVSAQVAAELKDLTQEERDDFLSCIGVESDGTKELIEVAYRQLNLLTYFTTGEKETRAWTIKRGFTAPQAAAVIHTDFEKGFIKAETVHYDDFVTSGGFAGAKEKGVWQLEGKDYVVQEGDVIVFKVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTA6</accession>
    <name>A4RTA6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_29941</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Nucleoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416107.1">
        <property type="nucleotide sequence ID" value="XM_001416070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTA6"/>
    <dbReference type="STRING" id="436017.A4RTA6"/>
    <dbReference type="GeneID" id="5000545"/>
    <dbReference type="Gramene" id="ABO94399">
        <property type="protein sequence ID" value="ABO94399"/>
        <property type="gene ID" value="OSTLU_29941"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29941"/>
    <dbReference type="eggNOG" id="KOG2020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011906_0_0_1"/>
    <dbReference type="OMA" id="WAFKHNN"/>
    <dbReference type="OrthoDB" id="27218at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000022">
        <property type="entry name" value="protein EXPORTIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041123">
        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18777">
        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="6">
        <location>
            <begin position="33"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1059" mass="120802" checksum="337CDE52CE425D94" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTC6</accession>
    <name>A4RTC6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="3 10">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_86391</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Divalent metal cations. Probably Zn(2+).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="3 10"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416102.1">
        <property type="nucleotide sequence ID" value="XM_001416065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTC6"/>
    <dbReference type="STRING" id="436017.A4RTC6"/>
    <dbReference type="GeneID" id="5000162"/>
    <dbReference type="Gramene" id="ABO94394">
        <property type="protein sequence ID" value="ABO94394"/>
        <property type="gene ID" value="OSTLU_86391"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86391"/>
    <dbReference type="eggNOG" id="KOG2628">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065200_0_2_1"/>
    <dbReference type="OMA" id="IKREEAY"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672871" description="Protein-S-isoprenylcysteine O-methyltransferase" evidence="11">
        <location>
            <begin position="31"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="22067" checksum="53EE330C5EEB8C31" modified="2007-05-15" version="1">MSLPTPTTGAALRLFAAFLAHFHLSEFAFALRFNPQDVSTRSFLLSRPYAAAMTCGVIEFAASSALMPERKASLVRGTFYLGAFMCVFGEWLRKSAMCTAGAAFTHLIQTRRRATHVLVTEGAYAYARHPGYLGWFIWALGTQLVLGNVASVAAFAVVTWVYFKRRITYEERHLRNMFSEYDAYAKRVRTWIPGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTD4</accession>
    <name>A4RTD4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_29913</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416094.1">
        <property type="nucleotide sequence ID" value="XM_001416057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTD4"/>
    <dbReference type="STRING" id="436017.A4RTD4"/>
    <dbReference type="GeneID" id="5000539"/>
    <dbReference type="Gramene" id="ABO94386">
        <property type="protein sequence ID" value="ABO94386"/>
        <property type="gene ID" value="OSTLU_29913"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29913"/>
    <dbReference type="eggNOG" id="KOG2241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_6_5_1"/>
    <dbReference type="OMA" id="EGHDMPY"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000225">
        <property type="entry name" value="tyrosine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF47">
        <property type="entry name" value="NUCLEIC ACID-BINDING, OB-FOLD-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="50"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="217" mass="23237" checksum="31B578D53345B3A4" modified="2007-05-15" version="1">MRAAAALASRASRFARSNARAPGARARGRARSTVARETRANGKAAELAPLEQRVDLRVGRVLSAKRHEDAEKLYIEEIDLGEPEGPRTILSGLVPYMSAEDIEGKSVIVFANLKARKLAGIPSHGMILAASDASHENVELLVAPEGAVVGERVRFGESDEPQAEPQTPNQIQKKKTWEELQPLLVTNQDCVATYEGAPMMTSAGPVKCATMKGATIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTF8</accession>
    <name>A4RTF8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416324.1">
        <property type="nucleotide sequence ID" value="XM_001416287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTF8"/>
    <dbReference type="GeneID" id="5000154"/>
    <dbReference type="Gramene" id="ABO94617">
        <property type="protein sequence ID" value="ABO94617"/>
        <property type="gene ID" value="OSTLU_29897"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29897"/>
    <dbReference type="HOGENOM" id="CLU_618725_0_0_1"/>
    <dbReference type="OMA" id="WLYASQI"/>
    <dbReference type="OrthoDB" id="10512790at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="47954" checksum="6F553741376B81C4" modified="2007-05-15" version="1">MDDDSTLPAAPSARALGDEVSLEQCERLFVCAHFAECRAMCERVYAAYVDDPSAPRPLVRGTSSDARESGARARATAREDSGIDAAVAAAARRLRRPERYLDEIYGECSCSEDEDEGSERNAERRALARDAESVRWPVEDLRERDAAWVTSCLWVQCKFKSKDGLGRTMAEDFAELRRGVRVGTPPRLGPTARMLWCKLKWEEGAGKTAGSREEAEIEREILALFDDAAAANVLNDESMSEELNVAWRDALRNLGWLYASQILAAQREDEDAAHAWLDKREDLLDEQIIVLTRSWIQKANINKNYRFSVSYDEHTGRVMVKNQRVDDDGEDENASDDDAPAEENETEITKSSPTAAPEPVEDDGTNAEKVSTVDALASRVTHVVREIARDPTGDYSLRAYATVAVSAYVAFSLVQRVNDWRNRAKKLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTN7</accession>
    <name>A4RTN7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416819.1">
        <property type="nucleotide sequence ID" value="XM_001416782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTN7"/>
    <dbReference type="STRING" id="436017.A4RTN7"/>
    <dbReference type="GeneID" id="5001080"/>
    <dbReference type="Gramene" id="ABO95112">
        <property type="protein sequence ID" value="ABO95112"/>
        <property type="gene ID" value="OSTLU_24151"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24151"/>
    <dbReference type="eggNOG" id="KOG1737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007105_6_0_1"/>
    <dbReference type="OMA" id="MSEPLQY"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120009">
        <property type="term" value="P:intermembrane lipid transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000001">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF136">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="373"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="51355" checksum="CA6230B886BE87BC" modified="2007-05-15" version="1">MDGFEDDVRAGLPPKQPSDAAKDAKAHRSWISRVGTWGSDLVNAVGDGLNYLAGYDELEVTEGGEEAHAGEHTEVDAVDDRKAMWGQLKDMLGSDIMSMFSLPTFLMEPVSTLQKMAEIMQYQRLLEEANEEEDADVRLAKVTAFAVAVYSTMERAKKPFNPILGETFELKMNDGSTYLAEQVSHHPPIGAGHVKTKSFTYDITSAVTTKFMGNWVDVFPVGRTRITLHKTGETFNIVPPSSRVNNLIIGRIWIDTFGEMKVINLTSGAVAELDFKACGIMSFARYVCSGVIKRPDGTTALNVFGHWNRDLSYTRAGEDEDEKVQLWQVDEWPVPANKYGFPTYTIKMNEMASAPDYGLLASDSRLRPDRVALDEGDSSATSLKTQLEEKQRAERRTRKEKGEVWTPRWFKKAEHADLHELEKDVGTDVWEFNDDYDSKKPEGVPTKFSPWQYPELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTP3</accession>
    <name>A4RTP3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_14406</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416527.1">
        <property type="nucleotide sequence ID" value="XM_001416490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTP3"/>
    <dbReference type="STRING" id="436017.A4RTP3"/>
    <dbReference type="GeneID" id="5000733"/>
    <dbReference type="Gramene" id="ABO94820">
        <property type="protein sequence ID" value="ABO94820"/>
        <property type="gene ID" value="OSTLU_14406"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14406"/>
    <dbReference type="eggNOG" id="KOG4293">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1117256_0_0_1"/>
    <dbReference type="OMA" id="RMKFLFP"/>
    <dbReference type="OrthoDB" id="366214at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130">
        <property type="entry name" value="CYTOCHROME B561 AND DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130:SF171">
        <property type="entry name" value="OS01G0895300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="8">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="26971" checksum="4DE2003AC7279A4F" modified="2007-05-15" version="1">MTRRGGLIINFSTGDATSMTIKSAIKRDVTHGVLMLVAWGVLMPTASAAPRMKFLFPDGKWFLMHQIGVVVGAVVFVTAGAMLLAEHDEREDAHSESSTFDAHSRIGIAVGFLWLAQFLLGVFRPNKNITDSARFGFIPSSWRKAWFLAHASLGPITIGLASVALVLGAVLIRDKYVGETDSGVKFLADGGVYGIMAAVWFVCAFGVWRDGFAKAKGGLENYVAREPTPSESNRNAREMRFTGITVSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTX5</accession>
    <name>A4RTX5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cation/H+ exchanger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416572.1">
        <property type="nucleotide sequence ID" value="XM_001416535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTX5"/>
    <dbReference type="GeneID" id="5001066"/>
    <dbReference type="Gramene" id="ABO94865">
        <property type="protein sequence ID" value="ABO94865"/>
        <property type="gene ID" value="OSTLU_30420"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30420"/>
    <dbReference type="eggNOG" id="KOG3826">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018415_4_0_1"/>
    <dbReference type="OrthoDB" id="423807at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098662">
        <property type="term" value="P:inorganic cation transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051843">
        <property type="entry name" value="CPA1_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31102">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31102:SF1">
        <property type="entry name" value="CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="33033" checksum="7C9AA9A221B7A163" modified="2007-05-15" version="1">MLATTALGAAFFELPIATAFALGFLMCGISLAVVIPPAVAMKRTGLGVEAGVPDLVVAASSFDGILCIVGFGVCGGVVAASGGGGASAMAWKVPTQLVVGALGGVGAAEFATRSGLLSAPGNRASATSDASMILSVVLLILFAAKRLEVNGGGALASIAFCVAVSSAWKSRGMEDALKETTAFMNALWAEFAAPLLFVIIGCTLDLHAMTGDVAAKAIGIIALGGIVRALGVFLSTAASESMNLRERAFIALAWTPKATIQAALANVVYDQAVTAHGVGSPEALDGEKLLQTALLSILITAPLGAWCIAYFAPRLLKQETKPVAIAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU42</accession>
    <name>A4RU42_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ENT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_14528</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416608.1">
        <property type="nucleotide sequence ID" value="XM_001416571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU42"/>
    <dbReference type="STRING" id="436017.A4RU42"/>
    <dbReference type="GeneID" id="5000562"/>
    <dbReference type="Gramene" id="ABO94901">
        <property type="protein sequence ID" value="ABO94901"/>
        <property type="gene ID" value="OSTLU_14528"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14528"/>
    <dbReference type="eggNOG" id="KOG4675">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1104043_0_0_1"/>
    <dbReference type="OMA" id="CLTYEIN"/>
    <dbReference type="OrthoDB" id="1737049at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ENT domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="EMSY-LIKE_plant"/>
    </dbReference>
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        <property type="entry name" value="ENT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036142">
        <property type="entry name" value="ENT_dom-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33432:SF22">
        <property type="entry name" value="OS10G0436850 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33432">
        <property type="entry name" value="PROTEIN EMSY-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03735">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01191">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51138">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENT" evidence="4">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="269" mass="29844" checksum="D459889474FB5CF0" modified="2007-05-15" version="1">MSISNSVRKLETDAYGAILKAMAVTGLTWEREEFLGRLRVELNVSSEEHLKMRDQVETDERVAKLRQGLTDHKDTQEAKRQRTEAAAMAAAMAPAAPPRAHAAPRRKPQHSATRAPKITPAQLEAMGVNELICKKVKRFWPSEGGWFDCIITDYNTETKQHCLTYEINTPNESYEWADISTFSPHEFKIEEGRVDIRELQAFTQGPGAAAAQAQANTSVVGAPADHIVAAATKARDPAKFEAVKTSLTAEEEALRKQLAELEDSEDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUB8</accession>
    <name>A4RUB8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_34381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416933.1">
        <property type="nucleotide sequence ID" value="XM_001416896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUB8"/>
    <dbReference type="STRING" id="436017.A4RUB8"/>
    <dbReference type="GeneID" id="5001112"/>
    <dbReference type="Gramene" id="ABO95226">
        <property type="protein sequence ID" value="ABO95226"/>
        <property type="gene ID" value="OSTLU_34381"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34381"/>
    <dbReference type="eggNOG" id="KOG0145">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_878095_0_0_1"/>
    <dbReference type="OMA" id="NEYGPDE"/>
    <dbReference type="OrthoDB" id="266138at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="237"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="34472" checksum="159738CB5D63CC3B" modified="2007-05-15" version="1">MYSDGQGYAATTPSSSRKHANLYVKNISERVDELTLRRLFEACGEVQSCCVIRDVSTNKSRGFGFVKFVSTARAEDAIERFNGKEYAGKMLEVKFANTDGESDGAGGAANAPPSDNVYVKGLPPSWTHDDLKAFFTHFGHIVECRLLHANRSTSSGALIRFLRESEATAAVTRANGRLLVPNGPPLVVRYAEAQGKNNKHDFAALAVLGSSPSHKFDAPMQSHQKFASATSMAQGGATMCIQNLPPAADELFLYKTFAPFGAINSVQIVRDDWTGLCSGVAVINFRSYSDACDAQRASQNGKSRLSISVQLQTANLANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUQ8</accession>
    <name>A4RUQ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1995 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417002.1">
        <property type="nucleotide sequence ID" value="XM_001416965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUQ8"/>
    <dbReference type="STRING" id="436017.A4RUQ8"/>
    <dbReference type="GeneID" id="5001055"/>
    <dbReference type="Gramene" id="ABO95295">
        <property type="protein sequence ID" value="ABO95295"/>
        <property type="gene ID" value="OSTLU_92473"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92473"/>
    <dbReference type="eggNOG" id="ENOG502QPSS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_883938_0_0_1"/>
    <dbReference type="OMA" id="PWRILVK"/>
    <dbReference type="OrthoDB" id="515480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36365">
        <property type="entry name" value="OS05G0500400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36365:SF1">
        <property type="entry name" value="OS05G0500400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1995" evidence="2">
        <location>
            <begin position="41"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="315" mass="33071" checksum="28A08E546CEF7077" modified="2007-05-15" version="1">MRATTPRVAPGVAPARDGRRRGVARRVVARAAGADEAAAPPRGKSEAYDQARVAVERALEKSTKRATKRRRSSGRAVGKPARLAVELPVNDDSDAALIEMATGTLGDGARDATAVFGRASAAKLAREMGSAMECVSVDDAWTAADAAARDGIIALVGVPSDRVEAAMRKCRAGEGRPTVCVNVEWEHDGDGGLAWSMSRQQAGVDDAAPSDVEAFANSFVVVYSFLPLNIQASMFASSLEGAVFKCVRGGAPAGTPWRILVKEKGAFAQVGAMQRRPQQTDLEAALYNSIAAKSPVNEAVGKASGFFRGLMNKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUY2</accession>
    <name>A4RUY2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF92 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_5597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="OSTLU_5597"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="DUF92_TMEM19"/>
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        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
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    </dbReference>
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    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="25229" checksum="243A61E12AA9711F" modified="2007-05-15" version="1" fragment="single">VLDGSPGLRAAAMANTAVFTSGFGVLRLGLTLAGIAHSWFLGTVVMAAFGVGGYALVCAYFIVGSAVTKIKLKEKQAEGIAEARGGLRGPGSVWGSGTAGILCAIAALSGWTPVSLELWRIGFVASFCSKLSDTTASEIGKAYGKTTYMSTPPFKLVPRGTEGAVSVEGTVAGIVVSGLFAGLAFIIGQLDAVGVGVCVLAAFIATTFESMLGAAVQGRKGFDWMSNDVVNGIQITLAAGVAIALRTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVZ7</accession>
    <name>A4RVZ7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417459.1"/>
    </dbReference>
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        <property type="gene ID" value="OSTLU_24410"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24410"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
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            <begin position="165"/>
            <end position="212"/>
        </location>
    </feature>
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        <location>
            <begin position="378"/>
            <end position="547"/>
        </location>
    </feature>
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        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
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        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
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        <location>
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            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="425"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="547" mass="58249" checksum="B3D2AFE79D846842" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW42</accession>
    <name>A4RW42_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_37370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Gramene" id="ABO95552">
        <property type="protein sequence ID" value="ABO95552"/>
        <property type="gene ID" value="OSTLU_37370"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37370"/>
    <dbReference type="eggNOG" id="KOG1454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OMA" id="ASTDHWR"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46438">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46438:SF2">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="51"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="314" mass="34578" checksum="BC323F5C046B7224" modified="2007-05-15" version="1">MDSISARGALELETDARGVERVKLRESGWNTWNWRGYACNYISAGEDNDGPIVTLVHGFGAHSYHWRYTIPALARAGYRVYALCMLGYGWSPKVEEEYCMEFWGQQVVDFTKEVAGASETDKTIIVGNSIGALAALFAASTQPQACKGLCLVNSAAQRAVGDAKEIDGKSADSFADKLRETFSRAVATAIFYSTKFRIRQILNQVYEFDVDDDLVRSIDLAAQDPGAIKTFYQLSLAGSRTKVKAGDLLADYDGDLMLLWGEKDPWMTPTKAARIREIKPNAVYAPVLGGHCPHDDAPTESNAALLRWAETLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW89</accession>
    <name>A4RW89_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_92626</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417284.1">
        <property type="nucleotide sequence ID" value="XM_001417247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW89"/>
    <dbReference type="STRING" id="436017.A4RW89"/>
    <dbReference type="GeneID" id="5001479"/>
    <dbReference type="Gramene" id="ABO95577">
        <property type="protein sequence ID" value="ABO95577"/>
        <property type="gene ID" value="OSTLU_92626"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92626"/>
    <dbReference type="HOGENOM" id="CLU_635524_0_0_1"/>
    <dbReference type="OMA" id="FANVQCF"/>
    <dbReference type="OrthoDB" id="446293at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:endocytosis"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF3">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="5">
        <location>
            <begin position="198"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="432" mass="47382" checksum="31717DD055CFBB49" modified="2007-05-15" version="1" fragment="single">VDVHALAHDLARDANVEDGRVWGPRGERDDGGRFDGGAEGGASSYDDRAQHENVEERDVGDARARKPREVSADERINATATAVIKAGSSGHSVEAFNGSSDDMAFSDRLAVATAKISTLAAQLKEKTAAARDTRAKEKALGGKELLRRLQETASSQSAQRAPGLVSLQSMRRGEGAAAPTVDESGKVVKGIGYKLSAATRRTSQRLLQSFGTAEKMRDDEFKTLWNSVQQQESILKEIAQVSTAYKHAQRAVFDMSKRLATLIRNLVETGDKNNVWDGAPTVAREAALREACKMVDVADALVARCTPLTEEVFDWNIVEPAAHRSKELPAYKACVAKRAAYMQDMDAFDRQLGALQKRSPKNADEYAVKEEQARRAKERFQDFSSKLVEELQIVDGTRYEMAYSIARGFANVQCFNLERQLDVARTLRGGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWU1</accession>
    <name>A4RWU1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417635.1">
        <property type="nucleotide sequence ID" value="XM_001417598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWU1"/>
    <dbReference type="GeneID" id="5001457"/>
    <dbReference type="Gramene" id="ABO95928">
        <property type="protein sequence ID" value="ABO95928"/>
        <property type="gene ID" value="OSTLU_31456"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31456"/>
    <dbReference type="HOGENOM" id="CLU_2125248_0_0_1"/>
    <dbReference type="OrthoDB" id="10558939at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="114" mass="12332" checksum="4E580C714778273A" modified="2007-05-15" version="1">MFTSSTFRNPEFMETCARDGVSASDAFATGAKFAFDESPVEEEDFARALADEQKRVTEKYLAKRNGISFHSAGPQQPVVAPPPADEARQAAINSQIAKARVEARIALQKAGKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX22</accession>
    <name>A4RX22_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_31539</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417921.1">
        <property type="nucleotide sequence ID" value="XM_001417884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX22"/>
    <dbReference type="STRING" id="436017.A4RX22"/>
    <dbReference type="GeneID" id="5001679"/>
    <dbReference type="Gramene" id="ABO96214">
        <property type="protein sequence ID" value="ABO96214"/>
        <property type="gene ID" value="OSTLU_31539"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31539"/>
    <dbReference type="eggNOG" id="KOG1609">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039981_2_1_1"/>
    <dbReference type="OMA" id="FITHQIA"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46158">
        <property type="entry name" value="OS02G0165000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46158:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="8">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="32"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="250" mass="27506" checksum="BC3A49CD5E658064" modified="2007-05-15" version="1">MPPRVDASTPCPSATHPAPRPSDDDAPADAVCRVCLCDVEELPESRLVKLECACVGVYVHETCAEKWLRTKGSNVCEVCRESTQFDVPESFVGRLLRRAGVASERDRGDDAREYGPAVGDVIWIFLTTFCSVWVCLRLLLGIPIGPALAMSYCFGLGILMGVGFFIIPLRRASVPRSDSRAFLWLYALSMFITHQIAFGLALRPIPTQERRIKHAFSLTFAISIAAFSYPQIVMLGGCLWRALARGDAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX24</accession>
    <name>A4RX24_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417678.1">
        <property type="nucleotide sequence ID" value="XM_001417641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX24"/>
    <dbReference type="GeneID" id="5001971"/>
    <dbReference type="Gramene" id="ABO95971">
        <property type="protein sequence ID" value="ABO95971"/>
        <property type="gene ID" value="OSTLU_92705"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92705"/>
    <dbReference type="eggNOG" id="ENOG502R76F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_759891_0_0_1"/>
    <dbReference type="OMA" id="SWIANES"/>
    <dbReference type="OrthoDB" id="2161133at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16128">
        <property type="entry name" value="FAD/NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16128:SF5">
        <property type="entry name" value="FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="39248" checksum="269DE62A4DAF92DB" modified="2007-05-15" version="1" fragment="single">VTLFDGGRAPGGRASTREGRRGAWEHGARFVDVERERERERDDDDDDAADAWMRDRAREGAFVRWEGAVVALRGGRAVKKRLGARRTATPSFGAVAKALLEKVDLRASARVVGFDASDVDGAGVVVKYRSAAPDEGGETRSMSGFDVVVLADKNAANVADALGVEELARAMREVPSVPSLVLMVTLNRAPAIEFVGAEIENDDALSWISNESSKPSRRRDANCWVAHSTDAYARAKVNLDTRPGTREHDAWMDAVANEMSESLLRILREAEANADVDVDGAPLEITYARAHRWGAAFPAAVAAGAEKSKFLRATSTSPTGRVTTVYAVGDYCVEHDRFGGFRAAVASGLACAEDILATKSARSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX25</accession>
    <name>A4RX25_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF2064 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417679.1">
        <property type="nucleotide sequence ID" value="XM_001417642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX25"/>
    <dbReference type="STRING" id="436017.A4RX25"/>
    <dbReference type="GeneID" id="5001680"/>
    <dbReference type="Gramene" id="ABO95972">
        <property type="protein sequence ID" value="ABO95972"/>
        <property type="gene ID" value="OSTLU_31542"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31542"/>
    <dbReference type="HOGENOM" id="CLU_1059004_0_0_1"/>
    <dbReference type="OMA" id="RATRANC"/>
    <dbReference type="OrthoDB" id="2018156at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018641">
        <property type="entry name" value="Trfase_1_rSAM/seldom-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529:SF1">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529">
        <property type="entry name" value="SLL1095 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09837">
        <property type="entry name" value="DUF2064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="29133" checksum="4EAF01857FC2E2C2" modified="2007-05-15" version="1">MLILFGRHPTPGRCKSRLARALNSDEAAAAIYDAIVRVVLLRTSRERDDRDTGGLQLKFSCASSDDVAACEALFATGGRWRACARNARDAAAIEVEAQTQVDDLGARIVEAFRREVDGDARSSDSSIGRAVCVAGTDVPEFSRAHALEALALVEGASSADAPRVAFGPSRDGGFYCVAARATRANCDALERALAGVRWSASTTLEECARNCRANGFDVRATMPELLDVDDDGDLDALLAERLAADDERESPAVRDAFAEMVRILENSRAARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX27</accession>
    <name>A4RX27_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417681.1">
        <property type="nucleotide sequence ID" value="XM_001417644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX27"/>
    <dbReference type="GeneID" id="5001682"/>
    <dbReference type="Gramene" id="ABO95974">
        <property type="protein sequence ID" value="ABO95974"/>
        <property type="gene ID" value="OSTLU_92707"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92707"/>
    <dbReference type="HOGENOM" id="CLU_541206_0_0_1"/>
    <dbReference type="OrthoDB" id="10497383at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="504" mass="56819" checksum="1F3CDA7DA06AF8D4" modified="2007-05-15" version="1">MARAKMTSRRAPGGKVRRPQFTVGSPRAPARDRVGASDAARRNRTLARVFALGEDWTVADARARERAFLAECDDGAWTGLTTYDALEEHGLFTAVVEAGWHELCRALGVDEDERAAYGPWRYVPGRISHEAVPWDDFDEMYWKHKAKGLVDDDLIETLEDEGDEDEYVTTHAKLSRDDVASLLEEYGKRYLFLIVREFEGADHVAAKSLALDANMEYVRHQHEQKSAHPGVPMARLLDPKELSFDEIKAMYKAAGLRVGKNAKRESLLRELVIEDRALELDAYGKAFAKVVKRLDVETKKLQDKIEKAVNKAVKSVIIDKWDTDRKNDFLATHDHWSDERKKAWHDGVASRLKKTQNAKKVQPKTTKAQPKTTKAQPKTTKAQPKTTKAQANKPAKPKRKRNDPLVTSDFAVGMELYVRGAKGETWHAEVTKVRPSNAKCPIEVAWLVKQSDDAYVYWDCAHRDVIDLRTVLETHAPGHFPAGKRARCVACEAAKTTCAKRAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX44</accession>
    <name>A4RX44_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_87200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417927.1">
        <property type="nucleotide sequence ID" value="XM_001417890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX44"/>
    <dbReference type="STRING" id="436017.A4RX44"/>
    <dbReference type="GeneID" id="5001979"/>
    <dbReference type="Gramene" id="ABO96220">
        <property type="protein sequence ID" value="ABO96220"/>
        <property type="gene ID" value="OSTLU_87200"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87200"/>
    <dbReference type="eggNOG" id="KOG1297">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061714_4_0_1"/>
    <dbReference type="OMA" id="NTRCALH"/>
    <dbReference type="OrthoDB" id="197967at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019129">
        <property type="entry name" value="Folate-sensitive_fs_Fra10Ac1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09725">
        <property type="entry name" value="Fra10Ac1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="205" mass="23163" checksum="0101A02911849D8C" modified="2007-05-15" version="1">MRRARGDDVARAALDRADFARLSPRARHAALLDAHERFCGANARRARGDGDALAREHRFVRDDEEDERRGDAWAVRLARRYHEKLYKAYAVFDATTRDGETGARWRTAAEVRAGKGQFTCGEKRCETSDGLASFECVFAYDEGGVRKKAMMKVRACARCAEKLGAGGGVSRAKPKDRKREKKDRKRKRDAEKDDAREALRGLLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXD7</accession>
    <name>A4RXD7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_8845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417981.1">
        <property type="nucleotide sequence ID" value="XM_001417944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXD7"/>
    <dbReference type="STRING" id="436017.A4RXD7"/>
    <dbReference type="GeneID" id="5001856"/>
    <dbReference type="Gramene" id="ABO96274">
        <property type="protein sequence ID" value="ABO96274"/>
        <property type="gene ID" value="OSTLU_8845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8845"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_4_3_1"/>
    <dbReference type="OMA" id="KLHYEGS"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="5"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="157" mass="17450" checksum="55B65F47BD658040" modified="2007-05-15" version="1" fragment="single">NPQCFLELRAGGYYLGRVVFEVKEDVAPITAKNFAQLCEYGCYAGTMFKVYPSNWIVGGDFTKLDESIYGAYFDDENFNLKHGGPGVLTMHNDGGGEPGRNGSQFMLTLDAKPQLDNRHVAFGQVIEGYDIVYALQKLGDARQEGETFQRITVERCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXE1</accession>
    <name>A4RXE1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_15391</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417734.1">
        <property type="nucleotide sequence ID" value="XM_001417697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXE1"/>
    <dbReference type="STRING" id="436017.A4RXE1"/>
    <dbReference type="GeneID" id="5001917"/>
    <dbReference type="Gramene" id="ABO96027">
        <property type="protein sequence ID" value="ABO96027"/>
        <property type="gene ID" value="OSTLU_15391"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15391"/>
    <dbReference type="eggNOG" id="KOG0080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_10_1_1"/>
    <dbReference type="OMA" id="IRYCDDQ"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001129">
        <property type="entry name" value="ras-related protein Rab-44 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="203" mass="22331" checksum="F0795AFA04CB0EAE" modified="2007-05-15" version="1">MTSDDARAYDHLVKILLVGDSGVGKSSLLARFISDSFDEQGPTVGVDFKLKHVDVDGTRLKLTVWDTAGQERFRTLTSSYYRGAHGVVFVYDVTSRESFENARETWRKEVEMYGTIANSVKIVIGNKIDREDERTVARKEGVAFAKEYGCLFLECSAKTKVRVAEAFDELVKGILDAPGLLVDEVDDGVKLGAYADRAGGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXH8</accession>
    <name>A4RXH8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pachytene checkpoint protein 2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_3211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. PCH2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418001.1">
        <property type="nucleotide sequence ID" value="XM_001417964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXH8"/>
    <dbReference type="STRING" id="436017.A4RXH8"/>
    <dbReference type="GeneID" id="5001827"/>
    <dbReference type="KEGG" id="olu:OSTLU_3211"/>
    <dbReference type="eggNOG" id="KOG0744">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028208_2_0_1"/>
    <dbReference type="OMA" id="NVCDSVQ"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19508">
        <property type="entry name" value="RecA-like_Pch2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000680">
        <property type="entry name" value="pachytene checkpoint protein 2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044539">
        <property type="entry name" value="Pch2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058249">
        <property type="entry name" value="Pch2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991:SF1">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23242">
        <property type="entry name" value="AAA_lid_TRIP13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="83"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="304" mass="33321" checksum="ABFD7911615DC2EB" modified="2007-05-15" version="1" fragment="single">LLAWQCALTTRAYGLCEDGPGEEIGEGDEIATYTEWSLPCVDFEGAWESLIFDDDEVKTRLLRYATAALLFGERGVDAQLISWNRVVLLHGPPGTGKTTMCKALAQRLSIRFNHIYSSSVLVEVNAHSLFSRWFSESGKLVSKLFGKIQELLEDEDSLVFVLVDEVESLAAARKSAANGSEPSDAIRVVNALLTQLDALKSRPNAIVLTTSNITEAIDLAFVDRADIKCYIGPPGMRARYEILRSCVLELIRRDLVQGAEPMEFDDGVAKGCPVSLTLREAAEACDGLSGRALRKLPFLAYSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXU4</accession>
    <name>A4RXU4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">RNA cytidine acetyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">18S rRNA cytosine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_38443</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51424"/>
            <dbReference type="Rhea" id="RHEA-COMP:13575"/>
            <dbReference type="Rhea" id="RHEA-COMP:13576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a cytidine in tRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in tRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53876"/>
            <dbReference type="Rhea" id="RHEA-COMP:13670"/>
            <dbReference type="Rhea" id="RHEA-COMP:13671"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417814.1">
        <property type="nucleotide sequence ID" value="XM_001417777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXU4"/>
    <dbReference type="STRING" id="436017.A4RXU4"/>
    <dbReference type="GeneID" id="5001766"/>
    <dbReference type="Gramene" id="ABO96107">
        <property type="protein sequence ID" value="ABO96107"/>
        <property type="gene ID" value="OSTLU_38443"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38443"/>
    <dbReference type="eggNOG" id="KOG2036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004652_0_0_1"/>
    <dbReference type="OMA" id="HLHYIMS"/>
    <dbReference type="OrthoDB" id="10067491at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990883">
        <property type="term" value="F:18S rRNA cytidine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051392">
        <property type="term" value="F:tRNA cytidine N4-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904812">
        <property type="term" value="P:rRNA acetylation involved in maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051391">
        <property type="term" value="P:tRNA acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11040:FF:000002">
        <property type="entry name" value="RNA cytidine acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002218">
        <property type="entry name" value="tRNA(Met) cytidine acetyltransferase TmcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03211">
        <property type="entry name" value="RNA_acetyltr_Nat10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033688">
        <property type="entry name" value="NAT10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007807">
        <property type="entry name" value="TcmA/NAT10_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013562">
        <property type="entry name" value="TmcA/NAT10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027992">
        <property type="entry name" value="tRNA_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="N-ACETYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925:SF5">
        <property type="entry name" value="RNA CYTIDINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05127">
        <property type="entry name" value="NAT10_TcmA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08351">
        <property type="entry name" value="TmcA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13725">
        <property type="entry name" value="tRNA_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TmcA/NAT10 N-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="TcmA/NAT10 helicase" evidence="12">
        <location>
            <begin position="276"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="14">
        <location>
            <begin position="518"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="Possible tRNA binding" evidence="15">
        <location>
            <begin position="757"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="619"/>
            <end position="621"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="717"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO96107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="986" mass="110133" checksum="3426780855E5BB25" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXU5</accession>
    <name>A4RXU5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_31820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417815.1">
        <property type="nucleotide sequence ID" value="XM_001417778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXU5"/>
    <dbReference type="STRING" id="436017.A4RXU5"/>
    <dbReference type="GeneID" id="5002141"/>
    <dbReference type="Gramene" id="ABO96108">
        <property type="protein sequence ID" value="ABO96108"/>
        <property type="gene ID" value="OSTLU_31820"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31820"/>
    <dbReference type="eggNOG" id="KOG2606">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046927_3_0_1"/>
    <dbReference type="OMA" id="EIEISMA"/>
    <dbReference type="OrthoDB" id="409956at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF6">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="4">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="72" mass="7848" checksum="A56FEEEB08EF4749" modified="2007-05-15" version="1">MQQPMAWGGEPEIIMLTHVLASPISVYMAEGVGMRSIGVYGEDYADSAQYDDLAVLFHGAGHYEALRVFGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYF8</accession>
    <name>A4RYF8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_41004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418380.1">
        <property type="nucleotide sequence ID" value="XM_001418343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYF8"/>
    <dbReference type="STRING" id="436017.A4RYF8"/>
    <dbReference type="GeneID" id="5002440"/>
    <dbReference type="KEGG" id="olu:OSTLU_41004"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1463920_0_0_1"/>
    <dbReference type="OMA" id="PLLWTIA"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE STN8, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STN8, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="229" mass="25235" checksum="885B863328879415" modified="2007-05-15" version="1" fragment="single">LEDRGFPDALEDALGIRARDGDDEAKRANRCAKKIMRDLLGTVAALHDIGIVHRDLKPSNLVLMGKRFKLIDFGAACDLRSGENYDPEQGLLDPKYSPPEQFIMSEKTPAPPPLVAGVLAPLLWTIAQPQLFDSYSAGLILLQLGVPQLRGKNVMAPNGAFQRRLEDAGYDLRKWRADVESALNWDFSALDVNGGIAWDLACRLVTKRNILRRGRLDVGAALAHPFLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYN5</accession>
    <name>A4RYN5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ABCG) family transporter: multidrug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_1441</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418422.1">
        <property type="nucleotide sequence ID" value="XM_001418385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYN5"/>
    <dbReference type="GeneID" id="5002554"/>
    <dbReference type="Gramene" id="ABO96715">
        <property type="protein sequence ID" value="ABO96715"/>
        <property type="gene ID" value="OSTLU_1441"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1441"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_57_6_1"/>
    <dbReference type="OMA" id="RDANQTE"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="523" mass="58081" checksum="FCE5047C24934A72" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ10</accession>
    <name>A4RZ10_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_10647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418491.1">
        <property type="nucleotide sequence ID" value="XM_001418454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ10"/>
    <dbReference type="STRING" id="436017.A4RZ10"/>
    <dbReference type="GeneID" id="5002547"/>
    <dbReference type="KEGG" id="olu:OSTLU_10647"/>
    <dbReference type="HOGENOM" id="CLU_2678365_0_0_1"/>
    <dbReference type="OrthoDB" id="566279at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="75" mass="7994" checksum="FAAA9A1A54902030" modified="2007-05-15" version="1" fragment="single">LTKLSPDISRMTGLLTLIISGNGLVELPESIGKLKNLKVLEAENNDLVSLPASLAQCKNLEILRVSGNKIKSLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZG7</accession>
    <name>A4RZG7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_15936</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the THADA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418331.1">
        <property type="nucleotide sequence ID" value="XM_001418294.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RZG7"/>
    <dbReference type="GeneID" id="5002604"/>
    <dbReference type="Gramene" id="ABO96624">
        <property type="protein sequence ID" value="ABO96624"/>
        <property type="gene ID" value="OSTLU_15936"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15936"/>
    <dbReference type="eggNOG" id="KOG1810">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001343_0_0_1"/>
    <dbReference type="OMA" id="IITTACW"/>
    <dbReference type="OrthoDB" id="566306at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056843">
        <property type="entry name" value="THADA-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056842">
        <property type="entry name" value="THADA-like_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019442">
        <property type="entry name" value="THADA/TRM732_DUF2428"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051954">
        <property type="entry name" value="tRNA_methyltransferase_THADA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14387:SF0">
        <property type="entry name" value="DUF2428 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14387">
        <property type="entry name" value="THADA/DEATH RECEPTOR INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10350">
        <property type="entry name" value="DUF2428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25150">
        <property type="entry name" value="TPR_Trm732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25151">
        <property type="entry name" value="TPR_Trm732_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA (32-2'-O)-methyltransferase regulator THADA-like TPR repeats region" evidence="5">
        <location>
            <begin position="440"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2428" evidence="4">
        <location>
            <begin position="902"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA (32-2'-O)-methyltransferase regulator THADA-like C-terminal TPR repeats region" evidence="6">
        <location>
            <begin position="1152"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="839"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1870" mass="205058" checksum="B695F87C64307B7B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZI9</accession>
    <name>A4RZI9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_32404</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418805.1">
        <property type="nucleotide sequence ID" value="XM_001418768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZI9"/>
    <dbReference type="STRING" id="436017.A4RZI9"/>
    <dbReference type="GeneID" id="5002789"/>
    <dbReference type="Gramene" id="ABO97098">
        <property type="protein sequence ID" value="ABO97098"/>
        <property type="gene ID" value="OSTLU_32404"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32404"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012752_0_0_1"/>
    <dbReference type="OMA" id="IEHSKWT"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACB" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="494" mass="53380" checksum="2FD816F2CDF9777B" modified="2007-05-15" version="1">MSRAHDADGVEDAVLFDEDKTLLLDALERQASRGPCQGTRPWDLWDPAGALAYDAWSMLGNISPERAMELYCEVISSRYADWFDMLVRGMSEKQKRAMIATAKECALEYYRALASGALGESARLAQTKDARRALAFNSSTGPTAFLDEMFASAADDEFVRLPILSKVSPRARSGHMSAVVDGDTIFFSHGRGSRSRLLGDLWAFDLATGAWAERKLQWPGSTCAGAASATIGSKLYAFRGKSADDCDVDGVYSLTVSAIDLTADYASKDFKWTHVRCETSDEVSTPPRARSGHTSTAIGDRIFIFGGVDAKTGDDLDELWEFTPTTTVWKKLANGTRPRSSHAATSVDERYLLVCGGSTGNELCDCGAVDVYDVVKGEWGTVDGDNEDGDRPSPRAAHASVAIGNQWFVIGGGDNENATQDAYTFDLRACVDERKCRWTLFAESCALIGKEGMSASAVVSPSSKRVFLLLHGGLNEKGAVCDTIACRLAPLASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZL6</accession>
    <name>A4RZL6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PABS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418594.1">
        <property type="nucleotide sequence ID" value="XM_001418557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZL6"/>
    <dbReference type="GeneID" id="5002913"/>
    <dbReference type="Gramene" id="ABO96887">
        <property type="protein sequence ID" value="ABO96887"/>
        <property type="gene ID" value="OSTLU_15982"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15982"/>
    <dbReference type="eggNOG" id="ENOG502QR3C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_837814_0_0_1"/>
    <dbReference type="OrthoDB" id="2016285at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317:SF1">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="35393" checksum="3E6AED24952F6EEB" modified="2007-05-15" version="1">MSARAFAFASASRAQPTRALARRRDARRRASNADGASSWTVVVDRASSRFGSDLLVERVSSDCPNAAFAGALVLTRADAPDAVLSERRDDGRESRSGRAVGRGGVFDAFATLPATLEGEARRGKKTIGILGLGAGTCAEIMAGHHDDVDMIGWELDPAIVELARRHFAVGDLEREGRLRVVTGDAFEGCARSEIEFDGLIVDCFDENSVVVACLKDKATWEALAARLKPGGRVVANVSTGRGKGAKLDDAIACAQALADATSDEVTIWRAGACSIWNELILSGPEVNWRRVADEYGDFASLTKDWFYFKKPADAASGAPWLAKTLGVDNDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZM5</accession>
    <name>A4RZM5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418824.1">
        <property type="nucleotide sequence ID" value="XM_001418787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZM5"/>
    <dbReference type="STRING" id="436017.A4RZM5"/>
    <dbReference type="GeneID" id="5002920"/>
    <dbReference type="Gramene" id="ABO97117">
        <property type="protein sequence ID" value="ABO97117"/>
        <property type="gene ID" value="OSTLU_32441"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32441"/>
    <dbReference type="HOGENOM" id="CLU_649552_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="423" mass="44481" checksum="87E046E83A524C59" modified="2007-05-15" version="1">MNLGGWASASLAKAKAVVKEAAASDAARALRRDLKTFSSHVVGDDGARTRVVREDDDDAEDGNEDARDDAPKTADAVRLAETFASGAWAAFGGAANKAKRALENAEGVIENAASDPKTFATNVTKKTQSVGMGAFSALTSVVKATADVLAGDEDDDERAAAILVERLADFGAATAQAHVEVACERAMDALLNGASEDAQRRVRELVRELDATLTAEQSTANAAPPASPGDPATLVAVPLGDDAARAHDVESSVLVALIAAVDARAEEIGETLASTSGSSRDNFADTVAAFEEALDELRDECVCDGLAKLSTTTLEKIVRVVDSIRGGDWLDVDPVPAAVLARERVAGYDDDVKIFIEATKEATTALARRAHDALRDVWPRDAPTLLDVADASFEQLARDERACVDVTRRTLRQLAWVIAASSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZN7</accession>
    <name>A4RZN7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_9462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418602.1">
        <property type="nucleotide sequence ID" value="XM_001418565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZN7"/>
    <dbReference type="STRING" id="436017.A4RZN7"/>
    <dbReference type="GeneID" id="5002926"/>
    <dbReference type="KEGG" id="olu:OSTLU_9462"/>
    <dbReference type="eggNOG" id="KOG1472">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129458_3_1_1"/>
    <dbReference type="OMA" id="EPFENPV"/>
    <dbReference type="OrthoDB" id="515250at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090537">
        <property type="term" value="C:CERF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029614">
        <property type="entry name" value="CECR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47092">
        <property type="entry name" value="CAT EYE SYNDROME CRITICAL REGION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47092:SF1">
        <property type="entry name" value="CHROMATIN REMODELING REGULATOR CECR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="3">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="82" mass="8690" checksum="D67145C26103CE9F" modified="2007-05-15" version="1" fragment="single">LLAELRAHEDAEPFAVPVDARYAPDYYAVIERPIDVATMRARAGASAYASKDAFAEDLALMEANAVAYNGAGSTVAKMARAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZV5</accession>
    <name>A4RZV5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418636.1">
        <property type="nucleotide sequence ID" value="XM_001418599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZV5"/>
    <dbReference type="GeneID" id="5002657"/>
    <dbReference type="Gramene" id="ABO96929">
        <property type="protein sequence ID" value="ABO96929"/>
        <property type="gene ID" value="OSTLU_32522"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32522"/>
    <dbReference type="eggNOG" id="ENOG502SG0Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1505859_0_0_1"/>
    <dbReference type="OMA" id="PYADEGW"/>
    <dbReference type="OrthoDB" id="199317at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049226">
        <property type="entry name" value="DUF6823"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20709">
        <property type="entry name" value="DUF6823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="179" mass="19487" checksum="E875D7C5943A819F" modified="2007-05-15" version="1">MIGLKTSPLAAPVVVRRRRARAIARAGPFDFLRNNKDVGGRDTTWEAQQEILKKRRSGANLGKEVAARRAKVSRFVNKKLPAAEQKAIEAKNRAKANALSKEAVTGGIPLPMISLGMPEFDGGERFDLRGKYVDEGWVDPEDAKAAAGDWLFGGAFKKKASSAQKKPAATPKKKGWFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZX8</accession>
    <name>A4RZX8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DMT3502</name>
        <name evidence="6" type="ORF">OSTLU_16070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418645.1">
        <property type="nucleotide sequence ID" value="XM_001418608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZX8"/>
    <dbReference type="GeneID" id="5002859"/>
    <dbReference type="Gramene" id="ABO96938">
        <property type="protein sequence ID" value="ABO96938"/>
        <property type="gene ID" value="OSTLU_16070"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16070"/>
    <dbReference type="eggNOG" id="KOG0919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049101_0_0_1"/>
    <dbReference type="OMA" id="CPEMMKL"/>
    <dbReference type="OrthoDB" id="414133at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050750">
        <property type="entry name" value="C5-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098:SF1">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="43989" checksum="EB46E6EF9D75EB19" modified="2007-05-15" version="1">MAVATGGRFAERSASVKPIGRERPERRARRRVVRVASTRDARLVELYSGIGATRLALEPLVTLKSAIAVDNSDAANAVYEANFADAPRRVNVEHLDLNALFASGNGDEGRQGRRNDYVLTVSPPCQPYTRRGKGLASEDPRARSFHAVIDQLRAIEHVPRRIFVENVVGFESSDTRRALLNALGSRRYDVREFIVSPMALGIPYSRSRYYLIATLREGGFRAPTPAWLAGRELNDDGSVVTSDAQSSPSSSATLSEYIVADADGRVDLLLSPDTIKKYRRMLDVVHAKSRRCSTFTSGYGSTVFGGSVVLRGGNDELVSMLEVDVNETSGVARISERDIERFVGELRWFAVEEIKRLHGVRRDFTFDACSTKKAIFLLGNSISVDVVREVLRHLIQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZY8</accession>
    <name>A4RZY8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nuclear cap-binding protein subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_87731</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418651.1">
        <property type="nucleotide sequence ID" value="XM_001418614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZY8"/>
    <dbReference type="STRING" id="436017.A4RZY8"/>
    <dbReference type="GeneID" id="5002814"/>
    <dbReference type="KEGG" id="olu:OSTLU_87731"/>
    <dbReference type="eggNOG" id="KOG1104">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_553650_0_0_1"/>
    <dbReference type="OMA" id="DTIWAFE"/>
    <dbReference type="OrthoDB" id="10252707at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027159">
        <property type="entry name" value="CBP80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015172">
        <property type="entry name" value="MIF4G-like_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015174">
        <property type="entry name" value="MIF4G-like_typ-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412">
        <property type="entry name" value="CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412:SF2">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09088">
        <property type="entry name" value="MIF4G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09090">
        <property type="entry name" value="MIF4G_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G-like type 1" evidence="2">
        <location>
            <begin position="63"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G-like type 2" evidence="3">
        <location>
            <begin position="222"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="53458" checksum="F63003E58A3023A5" modified="2007-05-15" version="1" fragment="single">LEPSFTEGTGNADAWGPLERFVAEEYIIDTIWAFEPGYRRSATIPVTEQLASLPLPADQPEQCQFMVAETLFAELLSLPKPSFTPVLYHIIIQDLCKIIPTFPPKMAKTVGAMFRAIDRMDVGARDRLASWLAHQISCFDLVWPWSSWKHVMEQPDDAPQRTFCKEVLRKLCQLSFFERVQKSLIEELHPLLPGQAGINAEYVDAVAQEPVFGALKEMLASKKEGHEVLGWIQSQAASASPDVLLRALAVATLERGQKCITHHDVLLKRYALPIRDLVEKAGGEVLVDAAAGVWRGHPQMGPIAIERLLALDLVTPAAVVNWLLQRAAAFGEDDTYEIANVVCEFVCASKEQAIGKREALLRKLREAEAEAAAAGQAATELTEQGRVFEAQQAQAAEASAVEEISIHEAALASADAPVDRCAAITREICLNLCGGLVKAASGGASAAVADRILAFVRKYRAELALDADAVIKAAGTKKTAKSAVAAALGVHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S004</accession>
    <name>A4S004_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_16085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418659.1">
        <property type="nucleotide sequence ID" value="XM_001418622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S004"/>
    <dbReference type="STRING" id="436017.A4S004"/>
    <dbReference type="GeneID" id="5002871"/>
    <dbReference type="Gramene" id="ABO96952">
        <property type="protein sequence ID" value="ABO96952"/>
        <property type="gene ID" value="OSTLU_16085"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16085"/>
    <dbReference type="eggNOG" id="KOG1543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_495584_0_0_1"/>
    <dbReference type="OMA" id="TEFEHYM"/>
    <dbReference type="OrthoDB" id="497629at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="4">
        <location>
            <begin position="41"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="3">
        <location>
            <begin position="158"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="61228" checksum="4F93F705D5FFA554" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S042</accession>
    <name>A4S042_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_10662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418679.1">
        <property type="nucleotide sequence ID" value="XM_001418642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S042"/>
    <dbReference type="STRING" id="436017.A4S042"/>
    <dbReference type="GeneID" id="5002995"/>
    <dbReference type="KEGG" id="olu:OSTLU_10662"/>
    <dbReference type="eggNOG" id="KOG2445">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162320_0_0_1"/>
    <dbReference type="OrthoDB" id="424673at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021995">
        <property type="entry name" value="DUF3593"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35473">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35473:SF3">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12159">
        <property type="entry name" value="DUF3593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="86" mass="9643" checksum="69B053FC6F4E2454" modified="2007-05-15" version="1" fragment="single">LFGASLFPYLGFLYFLAKPEARCPRGTLFGFKFLLAFVFGTIPFAIYAKVEYDEILANVDVLHGVAESLLTMTNVFIVLGFRQGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S061</accession>
    <name>A4S061_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418918.1">
        <property type="nucleotide sequence ID" value="XM_001418881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S061"/>
    <dbReference type="GeneID" id="5002762"/>
    <dbReference type="Gramene" id="ABO97211">
        <property type="protein sequence ID" value="ABO97211"/>
        <property type="gene ID" value="OSTLU_16130"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16130"/>
    <dbReference type="HOGENOM" id="CLU_1043286_0_0_1"/>
    <dbReference type="OMA" id="AWRECAE"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="30469" checksum="6825DBD035C5BA8A" modified="2007-05-15" version="1">MPESDDDSDDDGLFGRRNTTLEVSWSDDDDALAGARAPGTKKSTPLRGALKLTSGKASSDDDDDDDARAFDAKISEMIATATDGSPRGSPSSAKKRETKRRAADARFAEATASLPRSKKNKSDDGGVGSSDATLESVQALKSACDALAQRPPPAYVPRAVEAHAVDDDEDDEDDEDVREVVNNGDKDGGVDVIEGNLNEETGNMITVSFQLPNGDKFERRVGETWTFAKIVGAWRECAEWCEMTCLLGSEQLTVVCDGDVVRGNETPETYGLEDGDTLDIIKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0C5</accession>
    <name>A4S0C5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_32692</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
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                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Bowler C."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
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                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
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                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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</entry>
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        <property type="project" value="UniProtKB-SubCell"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32442" checksum="F2D61D553677B6A9" modified="2007-05-15" version="1">MLVVTFMVKESDRTSARVRFNEGFWLVKGVIWLGLLVAAFAVTLNDYSGLVNVDRFFAAVFLLIQLIVLLGWVYDLNDKLMSGMDEGGNRSFALLLTSSAATYAFAFTLVGFLYKLWAPSSECHRNIALITCMLIVCVIFSVISLHARVNGGLFTSGAMTFYCMYVLASALASEPNNYACTPASKDGDLSSILSVIGFVFALFALGVTAHSASSKSAFAGEGAEGSEDPTSTFNVTFFHFVFFTASSYCAMTFTEWTNGRSAAGWESAWAKVAAAYASAALYTWALLAPFVLRNREFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0M7</accession>
    <name>A4S0M7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_87850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419003.1">
        <property type="nucleotide sequence ID" value="XM_001418966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0M7"/>
    <dbReference type="STRING" id="436017.A4S0M7"/>
    <dbReference type="GeneID" id="5003005"/>
    <dbReference type="Gramene" id="ABO97296">
        <property type="protein sequence ID" value="ABO97296"/>
        <property type="gene ID" value="OSTLU_87850"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87850"/>
    <dbReference type="eggNOG" id="ENOG502QR7R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_11_2_1"/>
    <dbReference type="OMA" id="MIHINCP"/>
    <dbReference type="OrthoDB" id="426235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13290)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="227" mass="24848" checksum="359CB652C77989E7" modified="2007-05-15" version="1">MSPATSPTSTSTSRRLVRGVVFDMDGTLCVSAALDFTEMRRRVGCETSDILGEVDSWNEARRTKAYEIIGEMEREALKTTVIAPGAMEVAATLDGMGIPRALVTRNAASSVEFFHDTVWTMAPFSPWLSREFKPYKPAPDSLLHICELWGCSPSEIIMVGDSAKDDVVSGNAAGALTVLLDSGRTGKWAEEFGVDKVPEQMVPHFVCADMNELHVLLTQSGHFEFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Z0</accession>
    <name>A4S0Z0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fanciful K+ uptake-b family transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_10668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419273.1">
        <property type="nucleotide sequence ID" value="XM_001419236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Z0"/>
    <dbReference type="STRING" id="436017.A4S0Z0"/>
    <dbReference type="GeneID" id="5003396"/>
    <dbReference type="KEGG" id="olu:OSTLU_10668"/>
    <dbReference type="eggNOG" id="ENOG502S21M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136788_3_0_1"/>
    <dbReference type="OMA" id="DVTPVIW"/>
    <dbReference type="OrthoDB" id="4696at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219:SF14">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="YLMG HOMOLOG PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="CCB3_YggT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9033" checksum="1AE344C90672683E" modified="2007-05-15" version="1" fragment="single">LGPLFALSTILFIVRIVMTWYPSVPYTKLPWVLAYAPTEPLLKPTRALVPPVGGVDVSPIIWVGMISFMNEILLGKQGLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Z9</accession>
    <name>A4S0Z9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">40S ribosomal protein S30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS30</name>
        <name evidence="5" type="ORF">OSTLU_32924</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419064.1">
        <property type="nucleotide sequence ID" value="XM_001419027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Z9"/>
    <dbReference type="STRING" id="436017.A4S0Z9"/>
    <dbReference type="GeneID" id="5003400"/>
    <dbReference type="Gramene" id="ABO97357">
        <property type="protein sequence ID" value="ABO97357"/>
        <property type="gene ID" value="OSTLU_32924"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32924"/>
    <dbReference type="eggNOG" id="KOG0009">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010412_5_1_1"/>
    <dbReference type="OMA" id="KRRILVW"/>
    <dbReference type="OrthoDB" id="3446at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="62" mass="6915" checksum="8E3583F33B1A959F" modified="2007-05-15" version="1">MGKVHGSLARAGKVRGQTPKVAKQEKKKQPKGRAFQRIKYNRRFVNVVVGIGKKRSPNSNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S100</accession>
    <name>A4S100_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_6735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419065.1">
        <property type="nucleotide sequence ID" value="XM_001419028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S100"/>
    <dbReference type="STRING" id="436017.A4S100"/>
    <dbReference type="GeneID" id="5003304"/>
    <dbReference type="Gramene" id="ABO97358">
        <property type="protein sequence ID" value="ABO97358"/>
        <property type="gene ID" value="OSTLU_6735"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6735"/>
    <dbReference type="eggNOG" id="ENOG502QR28">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077796_0_0_1"/>
    <dbReference type="OMA" id="ADTRDPW"/>
    <dbReference type="OrthoDB" id="1910737at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22992">
        <property type="entry name" value="MOC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045290">
        <property type="entry name" value="MOC1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36015">
        <property type="entry name" value="HOLLIDAY JUNCTION RESOLVASE MOC1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36015:SF6">
        <property type="entry name" value="HOLLIDAY JUNCTION RESOLVASE MOC1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="195" mass="20787" checksum="B8B18F31FD84E75B" modified="2007-05-15" version="1" fragment="single">SSNDADAEARSRDDWIVVGCDSDAHGALCVISGASVGSVRSVNVRDNPTSTVTVNGRARLRLDPDAMRGAVRALGVPKGTRVYLEEGGVEFGFSAQTAFVQGYNFGLWRGVLAAEEFEVRVVKPQAWKAAMGLKFKGSTKDDSIAMAKMLFPEIAGELKRKKDHGRAESLLIAAYGHVADGGAAAKEEDELCSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="109" xmlns="https://uniprot.org/uniprot">
    <accession>A4S264</accession>
    <name>A4S264_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="9">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_35051</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="9"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419478.1">
        <property type="nucleotide sequence ID" value="XM_001419441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S264"/>
    <dbReference type="STRING" id="436017.A4S264"/>
    <dbReference type="GeneID" id="5003632"/>
    <dbReference type="Gramene" id="ABO97771">
        <property type="protein sequence ID" value="ABO97771"/>
        <property type="gene ID" value="OSTLU_35051"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35051"/>
    <dbReference type="eggNOG" id="KOG0660">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="NANCDLC"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000046">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="86"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="449" mass="51014" checksum="E8F038FD4C2F0590" modified="2007-05-15" version="1">MGVEGDFDEETARLSARVAAAERRDALGGGGARRKRKEDAVADAARIHLLEPIDARTRGRETERVREQTPRRVWLGRHAFDVDERYDPIKTIGRGAYGVVCSANNRVAPLGARNTVAIKKLTNCFDSPVEARRALREVHLLRRLKHENVIKLEDIMMPVGDNGRMDDVYLVYELMDTDLHQIIRSKQALLDEHCQYFIYQILRGLKYVHSAKVLHRDLKPSNILLNANCDLCICDFGLARSMVERGRMMTSYVVTRWYRAPELLLNSEEYAASIDMWSVGCILAEIIDRKPLFPGKDFIHQMRLIIETLGSPEEADMDFISSPYARKYIASLPRKPKVDFAVLYPDANPLAIDLLERTLVFDPQRRISVDDALAHPYLASLHDASMEPTYTPAADDPHFKSLDEPDAHIPDEYLREAIYNQMLDMKSERAAARASSTSFAFAPRAQAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2M0</accession>
    <name>A4S2M0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_35077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419556.1">
        <property type="nucleotide sequence ID" value="XM_001419519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2M0"/>
    <dbReference type="STRING" id="436017.A4S2M0"/>
    <dbReference type="GeneID" id="5003612"/>
    <dbReference type="Gramene" id="ABO97849">
        <property type="protein sequence ID" value="ABO97849"/>
        <property type="gene ID" value="OSTLU_35077"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35077"/>
    <dbReference type="eggNOG" id="ENOG502S63F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080231_3_1_1"/>
    <dbReference type="OMA" id="LYRDCRF"/>
    <dbReference type="OrthoDB" id="564473at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009637">
        <property type="term" value="P:response to blue light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF8">
        <property type="entry name" value="PHOTOTROPIN-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="1" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="67"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12154" checksum="4429C33F1826D486" modified="2007-05-15" version="1" fragment="single">MDSCAEGITIADFTQPDQPLIYANVGFEVMTGYSVQETVGHNCRFLQGPGTDQNELNKLRNAIKKGEAVTVVLKNYKKSGEEFMNQLSLTPIRDADGQVMYYVGIQSDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2P4</accession>
    <name>A4S2P4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419567.1">
        <property type="nucleotide sequence ID" value="XM_001419530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2P4"/>
    <dbReference type="GeneID" id="5003567"/>
    <dbReference type="Gramene" id="ABO97860">
        <property type="protein sequence ID" value="ABO97860"/>
        <property type="gene ID" value="OSTLU_33522"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33522"/>
    <dbReference type="HOGENOM" id="CLU_635212_0_0_1"/>
    <dbReference type="OrthoDB" id="10560964at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="246"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="432" mass="49132" checksum="A864F562BD9B1C56" modified="2007-05-15" version="1">MASAHETILEEFSVLEDQLLAAQTREDEAVQYAEQVAADLAVTSRWCETLEAEQASAKALAEKAAKDAARVAETRAVELENRIKELELELLRNSVPEMERTRDEAEKAAREAREKYQEAHDQRESALEALENETAAKRELMEQVATLQRQLEDVERVRANDRAEIDRTREELRARYQAEKDSQDRFAKAQREHELELKTAREAVAEREDQLIKMRRDRDDVLHKLHLKEEEVVEARANMRASLLNVEALQTATNEAKETRQASNKELEDLRLCNSDLLVQVKHAKRELEDTSVALNKLTEKLQDLEDGSESAIRKRREAEDEIHDLKHSIIDLEAKNKALEMDREVAYQAADVARTENAKVSASVLDLTEEVARLKSALVAAQDSTRALLDEEAARLQRLAPTVQDSDYVSPAWLHDNSWQQPSVTLVSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2X1</accession>
    <name>A4S2X1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_93272</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCNDBP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419819.1">
        <property type="nucleotide sequence ID" value="XM_001419782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2X1"/>
    <dbReference type="STRING" id="436017.A4S2X1"/>
    <dbReference type="GeneID" id="5003878"/>
    <dbReference type="Gramene" id="ABO98112">
        <property type="protein sequence ID" value="ABO98112"/>
        <property type="gene ID" value="OSTLU_93272"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93272"/>
    <dbReference type="HOGENOM" id="CLU_1105092_0_0_1"/>
    <dbReference type="OMA" id="GAVWEAS"/>
    <dbReference type="OrthoDB" id="10528356at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049318">
        <property type="entry name" value="GCIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20936">
        <property type="entry name" value="GCIP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="7">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like C-terminal" evidence="8">
        <location>
            <begin position="128"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="252" mass="27300" checksum="97FA309270420BFB" modified="2007-05-15" version="1" fragment="single">VLAALRDAHAALTLETAKTLEARGNAGRCFREEISNLARASCEATKATIRAACARAREGRAANVRRGVGAVWEASKAFAKAPKDAVRAVAARLMTCARFVKDVDDEMRALGEDEEGAAASTRTDEDDLRFCDDDFSETEMANAKALRVFVKECVALLKALILPTVKEKTARLEALEPIVDACLEFQNCVEEIGAGAYPPQDVDDLKVHVRTAREAGKKMFECVRDAGIGDDETENAFARFDETGASVSLRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S308</accession>
    <name>A4S308_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Impact N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419631.1">
        <property type="nucleotide sequence ID" value="XM_001419594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S308"/>
    <dbReference type="GeneID" id="5003838"/>
    <dbReference type="Gramene" id="ABO97924">
        <property type="protein sequence ID" value="ABO97924"/>
        <property type="gene ID" value="OSTLU_33634"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33634"/>
    <dbReference type="eggNOG" id="KOG3299">
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    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
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        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="96" mass="10623" checksum="70F768D051596E1E" modified="2007-05-15" version="1">MDILNESRRVRAATHNILAYRVSRNDASKTFYQDHDDDGETAAGGRLLRLLVLADARDVVVVVSRWYGGIHLGPARFHVINACAKDALVALGEIHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S343</accession>
    <name>A4S343_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_16903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S343"/>
    <dbReference type="GeneID" id="5003520"/>
    <dbReference type="Gramene" id="ABO98145">
        <property type="protein sequence ID" value="ABO98145"/>
        <property type="gene ID" value="OSTLU_16903"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16903"/>
    <dbReference type="HOGENOM" id="CLU_357313_0_0_1"/>
    <dbReference type="OrthoDB" id="166585at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="785" mass="85078" checksum="97825EACB57C5FBF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S358</accession>
    <name>A4S358_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419861.1">
        <property type="nucleotide sequence ID" value="XM_001419824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S358"/>
    <dbReference type="GeneID" id="5003866"/>
    <dbReference type="Gramene" id="ABO98154">
        <property type="protein sequence ID" value="ABO98154"/>
        <property type="gene ID" value="OSTLU_16913"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16913"/>
    <dbReference type="HOGENOM" id="CLU_779355_0_0_1"/>
    <dbReference type="OrthoDB" id="10670389at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="356" mass="36886" checksum="8015C9EB0D396713" modified="2007-05-15" version="1">MDTVRRVLGAYLSGPVGEIAGSSPASSVKSLVPRRLSFARASSDGVARATNGNQASRAMSRFVRDAVGGKRARESSGTNGEGANGDVDGGGDDDGAGGKRPRHDDDVDVAVVRGEISGRGDEDLAPWPSAKRKRGIEDEEDAETPAAHRRRTSERASVQAPRARATPVLVAEKVLKGGRLDGFKALPKMSSRVAAPARRGPTNRRGLGGRRRIVDVRARVEFDELAEDKAERERLEATRAPALGLPSSYATTVASDRPKSNDSGGLGAALAEFKSTAATAAAEPAKSTTTSNPPSSTGGFTFTAAPPSSSTANPFSKPPTVGAPSATPFAFSAGAAADPAPGRRVVRARRPASRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4S398</accession>
    <name>A4S398_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419881.1">
        <property type="nucleotide sequence ID" value="XM_001419844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S398"/>
    <dbReference type="GeneID" id="5004230"/>
    <dbReference type="Gramene" id="ABO98174">
        <property type="protein sequence ID" value="ABO98174"/>
        <property type="gene ID" value="OSTLU_93311"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93311"/>
    <dbReference type="HOGENOM" id="CLU_714540_0_0_1"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="387" mass="43119" checksum="43D2954AB9F6CA89" modified="2007-05-15" version="1">MFVLISQIDTVLLPRLGERCRTADFTYNAGSAFELRDGRVRRYERCLAPPCSYTLPGGNYFLELIFKTFHLLLHARFLLTFDFSTDQTGLYGRAGVRISVEAFVTYDALPICDSWCVLISWWWCVPCTGVVAQTIATIGGCAPYQSQCGGSLVVFVTDAGEVRFGVQTFMDSYNNLPLSLGGGLRIVDVSVPGKGFFARDGIAFKVLCTYDGVSNTTKIYINDKLRGIADPFVMGQFLFRPFHNVSGNLHEKITIGNSMHSAASATNTLTDFQGMHETSNGTPDTRDGTLPAIGQFATYDASPLFDGSPTTQYFLPWRGTIHEVYVYFDNGLYQGIRYPSTCVHLEPVEPEADDFSDFVTRRRRLHETPVSRVRVGPRRRSDIRATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3C7</accession>
    <name>A4S3C7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Metallothionein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419896.1">
        <property type="nucleotide sequence ID" value="XM_001419859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3C7"/>
    <dbReference type="GeneID" id="5004132"/>
    <dbReference type="Gramene" id="ABO98189">
        <property type="protein sequence ID" value="ABO98189"/>
        <property type="gene ID" value="OSTLU_26009"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26009"/>
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        <property type="component" value="Chromosome 10"/>
    </dbReference>
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        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="51" mass="5067" checksum="320CE849DB9EB956" modified="2007-05-15" version="1">MACDKCGDACACGPGACACASALTCHACGHKSCGCARCRCACDSCQCQTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3F7</accession>
    <name>A4S3F7_OSTLU</name>
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        <recommendedName>
            <fullName evidence="7">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="9" type="ORF">OSTLU_26039</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
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            <strain evidence="9 10">CCE9901</strain>
        </source>
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        <text evidence="1 7">May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.</text>
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        <subcellularLocation>
            <location evidence="2 7">Membrane</location>
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    </dbReference>
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    <dbReference type="OMA" id="WREFLCT"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
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        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="P:vesicle-mediated transport"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00002501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006483"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="236" mass="26382" checksum="3E6FC0B12AEA7BF5" modified="2007-05-15" version="1">MASNGAANGVFSGNPLSLSLGRDDFTQWVKHRKNGDSAPATSSRDRDRRADVPDRRGSDSGGRASVRFKTPYMTVDDLKKPPKPWREFLCTDHLRRSYSVPKTMLECKIRLDGNAFEYVGNYARMALVFGGVMLYRNPTAVVGAYASAKLYAWMDRNIAATSEMQALKMIGTIISWFVMMYTKASAAMSTTMLLTMAFLVTHGCLRRLDAPKPIKIGKYTGISKWETQSPRKRPMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3R1</accession>
    <name>A4S3R1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420137.1">
        <property type="nucleotide sequence ID" value="XM_001420100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3R1"/>
    <dbReference type="STRING" id="436017.A4S3R1"/>
    <dbReference type="GeneID" id="5004091"/>
    <dbReference type="Gramene" id="ABO98430">
        <property type="protein sequence ID" value="ABO98430"/>
        <property type="gene ID" value="OSTLU_93346"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93346"/>
    <dbReference type="eggNOG" id="KOG2273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_401909_0_0_1"/>
    <dbReference type="OMA" id="MGECESG"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07596">
        <property type="entry name" value="BAR_SNX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
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        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="23"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="700" mass="75939" checksum="599F2A6F46D3530E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3T1</accession>
    <name>A4S3T1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L31, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL31</name>
        <name evidence="4" type="ORF">OSTLU_17087</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3T1"/>
    <dbReference type="STRING" id="436017.A4S3T1"/>
    <dbReference type="GeneID" id="5004014"/>
    <dbReference type="Gramene" id="ABO98440">
        <property type="protein sequence ID" value="ABO98440"/>
        <property type="gene ID" value="OSTLU_17087"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17087"/>
    <dbReference type="eggNOG" id="KOG0893">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112570_1_1_1"/>
    <dbReference type="OMA" id="EVWKQGI"/>
    <dbReference type="OrthoDB" id="9739313at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020052">
        <property type="entry name" value="Ribosomal_eL31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002258">
        <property type="entry name" value="PRK01192.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01144">
        <property type="entry name" value="RIBOSOMAL_L31E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="116" mass="13042" checksum="4E55646A426EA8C1" modified="2007-05-15" version="1">MGRESKPADVITREYTINLGKAITGVTFKKRAPRAVAAIKKFAQKTMKTSDVRIDVKLNKAVWSKGIRNVPKRIRVQISRKHNDNKDADEDLYSYVTVVDTPNGFKGLGTEVVDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Y0</accession>
    <name>A4S3Y0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CGS2</name>
        <name evidence="10" type="ORF">OSTLU_17120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420171.1">
        <property type="nucleotide sequence ID" value="XM_001420134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Y0"/>
    <dbReference type="STRING" id="436017.A4S3Y0"/>
    <dbReference type="GeneID" id="5004039"/>
    <dbReference type="Gramene" id="ABO98464">
        <property type="protein sequence ID" value="ABO98464"/>
        <property type="gene ID" value="OSTLU_17120"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17120"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_2_1"/>
    <dbReference type="OMA" id="HKKMHGV"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="386" mass="42213" checksum="A7DF17E6F4FFDE51" modified="2007-05-15" version="1">MLDHGTLLVRGAADAADDPTRSVIQPIYPSTTYARDDAHELPRFRDRTLCYARPDNPSVRACERTLRDLERGSDCALFSSGMAAVNAVLEGAVRGTSDASSFACSPSRGYFAVRARIREWCAARGVEVVEYDPDVPGRKAALVWVESPANPTWDVMDLEQVVAVARACDAGCVCVDSTVLTPICTKPLSFGVDVVMHSATKYLNGHGDVVAGALVTRECDDRWQRILHERKLGGATMGSMDAYLLSRGMRTLELRVRRQSESAMWIAHEFEQYLRSRIPHGAIVLYPGLQTDTTVESKNAHYDIVNRMCPNGVCDYWTCATSLGGFESLIEHRYSVECAPGEKEPHVPGGLLRLSVGLETKEDLLAGLKRGFDIALMDVVGASVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4M9</accession>
    <name>A4S4M9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_3307</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420294.1">
        <property type="nucleotide sequence ID" value="XM_001420257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4M9"/>
    <dbReference type="STRING" id="436017.A4S4M9"/>
    <dbReference type="GeneID" id="5004362"/>
    <dbReference type="Gramene" id="ABO98587">
        <property type="protein sequence ID" value="ABO98587"/>
        <property type="gene ID" value="OSTLU_3307"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3307"/>
    <dbReference type="eggNOG" id="KOG4283">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032951_2_0_1"/>
    <dbReference type="OMA" id="LRISWRH"/>
    <dbReference type="OrthoDB" id="497510at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000109">
        <property type="term" value="C:nucleotide-excision repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042238">
        <property type="entry name" value="Rad28/ERCC8/Ckn1/ATCSA-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202:SF1">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="50"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="137"/>
            <end position="179"/>
        </location>
    </feature>
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        <location>
            <begin position="250"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="256"/>
        </location>
    </feature>
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        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="373" mass="39344" checksum="CAF3343F5A92C680" modified="2007-05-15" version="1" fragment="single">VDLDACERRYLLVGGIDGSVRAYDTEAANRAGASGTASGTASGAAATSEEIGHTYATSCVRWLPSDTGMFFSGSYDKTVKCWDANSLRSACDVELPTKCRTLALSDAATTHSLVAIGSDDNVVRLWDPASNAIAHTLSGHRGSVHAIEWLRSNEHALATGGAEGDVRLWDIRSAGAYMILDRHNTQPSARVDAIKDAMYAGASTSGTIEAGPKPASRKMADSSARGRDERDDASRSRLFPAGDGYSSIPAPAHDGQVSGLRTTPCGMFIVSTGADGRIRRWDLSNGLNTYTPYDSAGAAPTASACQIAITADGERLYVPCTDTRVRVYRTHTGTLDAELKGHLDDVVACAYKDGGDAKLFTCGKDANVLVWAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4N6</accession>
    <name>A4S4N6_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">OSTLU_25231</name>
    </gene>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
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            <taxon>Eukaryota</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420466.1">
        <property type="nucleotide sequence ID" value="XM_001420429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4N6"/>
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    <dbReference type="Gramene" id="ABO98759">
        <property type="protein sequence ID" value="ABO98759"/>
        <property type="gene ID" value="OSTLU_25231"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25231"/>
    <dbReference type="HOGENOM" id="CLU_690001_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="400" mass="43722" checksum="6CB8D17663D40208" modified="2007-05-15" version="1" fragment="single">MRDAGRGRDGDDASRRDKARAAATTTTTTTRETDVERRSGAVKGERTDAGLGRERARATSQGAAGQDGVFNVDALRAAVDRHHRHFSSEVERAWRESNFSFGFGRGSAGGEFARESGDEGDDARAHRAGRKKTLSISAFREMARRASQDSLAKLDDAKFMERFEKLRRPRRSAGGDGRRTSESKRDERKSRPTSTQDLQALIAKNIPKAPAIPKWGEEWDVFKAIGTNFNQDDGALAKTPQRPNRTLNRRRAQSETVVDRSPGTSPRKSPKEAPETARSPREMSRSSSTDALTAMGDGDADHGARALSETSSPREGGANVLESLKKEITKKKDELASRLPRPPSLPKLTTDLQNAVRRFAGQPEEIVVKSPYDASLSSPGVVLKRAESKELAAELEASEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
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    <name>A4S5B6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_51117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420745.1">
        <property type="nucleotide sequence ID" value="XM_001420708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5B6"/>
    <dbReference type="STRING" id="436017.A4S5B6"/>
    <dbReference type="GeneID" id="5004844"/>
    <dbReference type="Gramene" id="ABO99038">
        <property type="protein sequence ID" value="ABO99038"/>
        <property type="gene ID" value="OSTLU_51117"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51117"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027681_1_0_1"/>
    <dbReference type="OMA" id="HVEEWNP"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019852">
        <property type="term" value="P:L-ascorbic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PP2C_SIG"/>
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    </dbReference>
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        <property type="entry name" value="PP2Cc"/>
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    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PPM_2"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="46"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="400"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="685" mass="73602" checksum="3EC11957A6A9DFD9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5C4</accession>
    <name>A4S5C4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420749.1">
        <property type="nucleotide sequence ID" value="XM_001420712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5C4"/>
    <dbReference type="GeneID" id="5004818"/>
    <dbReference type="Gramene" id="ABO99042">
        <property type="protein sequence ID" value="ABO99042"/>
        <property type="gene ID" value="OSTLU_26713"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26713"/>
    <dbReference type="HOGENOM" id="CLU_765899_0_0_1"/>
    <dbReference type="OMA" id="RTREMEY"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="362" mass="39999" checksum="0523B14A124B612B" modified="2007-05-15" version="1">MDDSFASARGELEDDGDGDDDRARVDGARRRVDGARASGREGDDFGDDDDEDDEDDDDDVGALLASTTRSLTEKLRQTCDALRESERRRTRGEEDAAAARRATRDASDALEREREARLDAERRARDAERALDETRTRGAGDVESLRRELREARTAGTNRAEADARAYDVAEARAVASVAVADLERARREFAKEWRTREMEYEATVRDLERRVSSLNARLAATSDDVERALERASARRHSTPSPTMKSPPSKMASPQSVDVGELRERLSEEQESRVATHAKILDLCRGRREMAREILDLSSCDVGRGEAENTHTALARARAHRAEAEALAAALAERVDVLERARVVDLRDLAAATASLASPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5M1</accession>
    <name>A4S5M1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Costars domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the costars family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420796.1">
        <property type="nucleotide sequence ID" value="XM_001420759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5M1"/>
    <dbReference type="GeneID" id="5004632"/>
    <dbReference type="Gramene" id="ABO99089">
        <property type="protein sequence ID" value="ABO99089"/>
        <property type="gene ID" value="OSTLU_26814"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26814"/>
    <dbReference type="eggNOG" id="KOG3376">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173478_0_0_1"/>
    <dbReference type="OrthoDB" id="9871914at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032970">
        <property type="term" value="P:regulation of actin filament-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1540">
        <property type="entry name" value="Costar domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044302">
        <property type="entry name" value="Costars"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027817">
        <property type="entry name" value="Costars_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038095">
        <property type="entry name" value="Costars_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46334">
        <property type="entry name" value="COSTARS FAMILY PROTEIN ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46334:SF1">
        <property type="entry name" value="COSTARS FAMILY PROTEIN ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14705">
        <property type="entry name" value="Costars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01283">
        <property type="entry name" value="Costars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Costars" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="66" mass="7031" checksum="967E8EA95C64F84E" modified="2007-05-15" version="1">MSRDRATQVKFGALVRDDEVANTFEALNGTLRAAKKRGKLTFAGELLLQGAHDDVDVVVVESAGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Y8</accession>
    <name>A4S5Y8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_93558</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420692.1">
        <property type="nucleotide sequence ID" value="XM_001420655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Y8"/>
    <dbReference type="GeneID" id="5004711"/>
    <dbReference type="Gramene" id="ABO98985">
        <property type="protein sequence ID" value="ABO98985"/>
        <property type="gene ID" value="OSTLU_93558"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93558"/>
    <dbReference type="HOGENOM" id="CLU_776931_0_0_1"/>
    <dbReference type="OMA" id="MCHRATE"/>
    <dbReference type="OrthoDB" id="497068at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672168" description="Cytochrome c domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="34"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="366" mass="40042" checksum="FD1CFE5FD79687CD" modified="2007-05-15" version="1">MSSRLLLCAVLFAFVPRSRAVDVVRANDRAPSNPIFPNGLDVFGRDARCRACHALVNALNENLIPSIAAERAKPASRATYGALDALIEAALAPACRLSATWRDATTRKACERLMETREDDVAAAYHRWIKRGGGSARDGGGTRGDGSRVTVAEARSGAYDPVGWNWNYEVCGRATGACREQLAMHELAEFDDDGAGDGEARKYRSEQRPADGETVDGMLKVTAGTFHEAVVRRDADVVAYVGFPKLDKWGHFYAAAALGSVREMFASNETAREGFEIAFVDGTHNDVPPPYGSDAQAPTVAMFAAGNKNWPRYMTDMNDGKLTAFEVLQFIMRTSAKPSTVQHAHWLTQSLSQNALHRRIWDDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S675</accession>
    <name>A4S675_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_27017</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420897.1">
        <property type="nucleotide sequence ID" value="XM_001420860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S675"/>
    <dbReference type="STRING" id="436017.A4S675"/>
    <dbReference type="GeneID" id="5005103"/>
    <dbReference type="Gramene" id="ABO99190">
        <property type="protein sequence ID" value="ABO99190"/>
        <property type="gene ID" value="OSTLU_27017"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27017"/>
    <dbReference type="eggNOG" id="ENOG502SCIV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_632146_0_0_1"/>
    <dbReference type="OMA" id="CNAACQR"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="399" mass="43134" checksum="009F68AFB2F179AB" modified="2007-05-15" version="1">MSTIVIDDKYALSDSDSVDADAPRCANCGVASDRLKKCAKCRRAHFCNAACQRAAWDAHARECVADANAKPAYKPPEPPRMPTKAEKEEAKESETRRIRETTLPRARAALRRDGVSTTVDLDELIEGLEDAIVFAIGEEDQGLTREVRLVLARAYLEAKRADECLHYLAPALEEARKEGGAASADAHTLAAKAHCAKGEKEQCRKELTAALDCASESTSDEAQCDTLLDAGIILHDLGDWERCAPLLSTAGEAAEKLGRLREAARAYNRAGSALLRSGRPDYAGRCWTRELRVLEADDSTDPGTLAQAFANCASAFLLTRGEDDDAFNLHKKSALTKARESGNDAEARVYLQLGNAYKLAGDAIDDSLARAKDCFEKAKSLSATDAGEIASRALEMLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S692</accession>
    <name>A4S692_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27035</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420904.1">
        <property type="nucleotide sequence ID" value="XM_001420867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S692"/>
    <dbReference type="GeneID" id="5005082"/>
    <dbReference type="Gramene" id="ABO99197">
        <property type="protein sequence ID" value="ABO99197"/>
        <property type="gene ID" value="OSTLU_27035"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27035"/>
    <dbReference type="eggNOG" id="KOG2551">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051938_2_3_1"/>
    <dbReference type="OMA" id="MAREGPF"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="29"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="247" mass="26918" checksum="D872C956A65656F1" modified="2007-05-15" version="1">MRAPTRAPPTTTPTTTCATRDAATAEPPRLKILSLHGFRTSREIFDAQARVARWREDYEDVARFHAIDAPHEGAGAATAEVRAFFGEDARSREWWNATTGRDGKTTYRGIEASLREIERACEEDGPYDGVLGFSQGATLAAIALATPELAERFAFGILVSGMRARAEETKGCDYGAIAVPTLHVVGLKDDVMPKAMSAGLYDAMTSSERTRETHDGGHRLPRVNVDGTPILRDFLAARLAARENSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6R2</accession>
    <name>A4S6R2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_7913</name>
        <name evidence="3" type="ORF">OSTLU_7923</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420989.1">
        <property type="nucleotide sequence ID" value="XM_001420952.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422906.1">
        <property type="nucleotide sequence ID" value="XM_001422869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6R2"/>
    <dbReference type="STRING" id="436017.A4S6R2"/>
    <dbReference type="GeneID" id="5004993"/>
    <dbReference type="GeneID" id="5006877"/>
    <dbReference type="Gramene" id="ABO99282">
        <property type="protein sequence ID" value="ABO99282"/>
        <property type="gene ID" value="OSTLU_7923"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01265">
        <property type="protein sequence ID" value="ABP01265"/>
        <property type="gene ID" value="OSTLU_7913"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7913"/>
    <dbReference type="KEGG" id="olu:OSTLU_7923"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042473_1_0_1"/>
    <dbReference type="OMA" id="CGDANTH"/>
    <dbReference type="OrthoDB" id="7763451at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343:SF22">
        <property type="entry name" value="LD29830P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343">
        <property type="entry name" value="SERINE/ARGININE-RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="6"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="104"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="20123" checksum="505509C74F9BCC10" modified="2007-05-15" version="1" fragment="single">EKAVPYTVFVKDVPASVSERELADVFASCGRIIDCRMCGDANTHKFSYAFVAFECAEAVDRALLLDKTPLHGKNIMVKKSDTAVIPVNPLLLPQNEREVESCARTIYVANVDKTVDSHALKLLFEDRAGPVNRLHLQVKNNAVANVAFVEFVDLESVGTALHLTGEQLGNRMIRVSASKTPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6U0</accession>
    <name>A4S6U0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_36723</name>
        <name evidence="9" type="ORF">OSTLU_41776</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPL family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421114.1"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4S6U0"/>
    <dbReference type="GeneID" id="5005007"/>
    <dbReference type="GeneID" id="5006862"/>
    <dbReference type="Gramene" id="ABO99444">
        <property type="protein sequence ID" value="ABO99444"/>
        <property type="gene ID" value="OSTLU_41776"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01163">
        <property type="protein sequence ID" value="ABP01163"/>
        <property type="gene ID" value="OSTLU_36723"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36723"/>
    <dbReference type="KEGG" id="olu:OSTLU_41776"/>
    <dbReference type="eggNOG" id="KOG0942">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002173_9_3_1"/>
    <dbReference type="OMA" id="PPFCVHR"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000011">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
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    </dbReference>
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        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF6">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UPL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
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    </dbReference>
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        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="28"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00057703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP01163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="376" mass="41653" checksum="8C3D46FACEB0A7CD" modified="2007-05-15" version="1">MGAVGYATIRVRRGHLLEDGIAGLSDKLTETLGGIIRVQFINQQGLEEAGVDGGGLFKDFLNDLIAEAFDPKFGLFVETPERTLYPNPASELHAGERHLQYFYFLGAILGKACYDGILLDVPLADFFLASLKGRHVEFNDLTTLDPELYRNLVSLKRYQGDVEDLCLYFTAIDRSGMEETVIELIPNGSSVPVTRANVPRYLHCMSIYLLRAQIYRQLSSMKAGFSIAVRKRWLDMFTPAELRLLISGNRTGSMDIDDMAANCEYSGGYEASHPTIRALWRVMRTISPDDQRLVLKFITSCSNTPLLGFSHLEPKLCVHRSGTAGTDAPDATADLTRLPTAATCMNLLKLPPYSSDDALREKLMYAVKSGSGFDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7C1</accession>
    <name>A4S7C1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421247.1">
        <property type="nucleotide sequence ID" value="XM_001421210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7C1"/>
    <dbReference type="GeneID" id="5005361"/>
    <dbReference type="Gramene" id="ABO99540">
        <property type="protein sequence ID" value="ABO99540"/>
        <property type="gene ID" value="OSTLU_18062"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18062"/>
    <dbReference type="HOGENOM" id="CLU_415868_0_0_1"/>
    <dbReference type="OrthoDB" id="501705at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="424"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="660" mass="71956" checksum="526242E7EDCEFD6C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7C2</accession>
    <name>A4S7C2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421428.1">
        <property type="nucleotide sequence ID" value="XM_001421391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7C2"/>
    <dbReference type="GeneID" id="5005515"/>
    <dbReference type="Gramene" id="ABO99721">
        <property type="protein sequence ID" value="ABO99721"/>
        <property type="gene ID" value="OSTLU_25504"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25504"/>
    <dbReference type="HOGENOM" id="CLU_848212_0_0_1"/>
    <dbReference type="OrthoDB" id="500029at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="349" mass="37591" checksum="404F8984DAD8FA0A" modified="2007-05-15" version="1">MLPPPRGLGARGLDRGAPGAFRGRATTRDDGARRRGTGRRTTTTTTTTTTTTGARGRAVRSIKEPNGASGAQSASGGASTSASGGDGKGGGWGKWFDKASELTRRATATTATWAQSTQNVVTKEMNEKAKLIQPSMNVAVDHFGPTARQINNLLKPVTEPIRKEWMNLKPETRRVMKGGFFGAFFGNLVLGWPARADRKRLRAKVEQMHLERAKMLVDDFSLEREVLSLNAENRRLEKRTLRAEMALNAIKRRLGEYVVAPKDETHFADPNLSGVMPGAPWANDLLDAVGSRVESARPSYTSEPKPTAVNSISSGKDGWSRDEAWAQGFLSASAEASSDGVDGGRPTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7D2</accession>
    <name>A4S7D2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93685</name>
        <name evidence="2" type="ORF">OSTLU_93704</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421432.1">
        <property type="nucleotide sequence ID" value="XM_001421395.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421466.1">
        <property type="nucleotide sequence ID" value="XM_001421429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7D2"/>
    <dbReference type="GeneID" id="5005560"/>
    <dbReference type="GeneID" id="5005596"/>
    <dbReference type="Gramene" id="ABO99725">
        <property type="protein sequence ID" value="ABO99725"/>
        <property type="gene ID" value="OSTLU_93685"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99759">
        <property type="protein sequence ID" value="ABO99759"/>
        <property type="gene ID" value="OSTLU_93704"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93685"/>
    <dbReference type="KEGG" id="olu:OSTLU_93704"/>
    <dbReference type="HOGENOM" id="CLU_2201429_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="108" mass="12085" checksum="360663E14E02F15E" modified="2007-05-15" version="1">MGCCLSTPAFYHPDLLAVLQVQGKHDFTSWRIAPLLKTHAPSPLYMRARDPDWSRNSPVAIELVDILNGALKDMGGWPICETIRCWSAIRFPVGCTPPKMVEAFEKVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7D6</accession>
    <name>A4S7D6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421434.1">
        <property type="nucleotide sequence ID" value="XM_001421397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7D6"/>
    <dbReference type="STRING" id="436017.A4S7D6"/>
    <dbReference type="GeneID" id="5005562"/>
    <dbReference type="Gramene" id="ABO99727">
        <property type="protein sequence ID" value="ABO99727"/>
        <property type="gene ID" value="OSTLU_27442"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27442"/>
    <dbReference type="eggNOG" id="ENOG502QSHE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_604678_0_0_1"/>
    <dbReference type="OrthoDB" id="3501663at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="99"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="453" mass="48628" checksum="29C5F3E9B55B95FE" modified="2007-05-15" version="1">MRWTPRDVAFALAIASALLAIAWPAFEARFSACPLGYGAKTTGPARARHHSTDAERDADVTTFANCAVGDAGAIKDITVSRHGRIIAVEDVPSTRFGVVLDCGGRALRSGFVDAHAHVVTGGFALDALDLRGVRSKEEFIETLARAIDAGKEKWVLGHGWDETSWGGETPSNAWTRGDERFVGAKVWVTRTCGHVGFASEAALEIAKITGAKTVIAGGIVELDDEGAPTGILKELATAAMSNAVPKRSRSERDEAFKRAFEYLLSKGITTVGDFGDIESLVAGADGYAQLWEDFETLERWDAVGDLPIRITSYMPLGDWASVQSHVAWNSGWTRENETAASRVRLGGVKAFLDGSLGGRTAAMMAPYLDDGSTSGHLMYPRGKREKILRKQATLADAAGLQIAVHAIGDAAVEQALELLASIERLDVIALGRGVSSVFRRPSVQRHETLALRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7T7</accession>
    <name>A4S7T7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytolic 80S ribosomal protein P2 Cytosolic 60S large ribosomal subunit protein P2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPP2</name>
        <name evidence="8" type="ORF">OSTLU_27612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the elongation step of protein synthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">P1 and P2 exist as dimers at the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421330.1">
        <property type="nucleotide sequence ID" value="XM_001421293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7T7"/>
    <dbReference type="STRING" id="436017.A4S7T7"/>
    <dbReference type="GeneID" id="5005229"/>
    <dbReference type="Gramene" id="ABO99623">
        <property type="protein sequence ID" value="ABO99623"/>
        <property type="gene ID" value="OSTLU_27612"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27612"/>
    <dbReference type="eggNOG" id="KOG3449">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114656_0_1_1"/>
    <dbReference type="OMA" id="AYLMATM"/>
    <dbReference type="OrthoDB" id="1227494at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001859">
        <property type="entry name" value="Ribosomal_P1/P2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00456">
        <property type="entry name" value="RIBOSOMALP2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="64"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="112" mass="10997" checksum="6673E27008965F6C" modified="2007-05-15" version="1">MKYVAAYLLAQLAGKESPSEADVKAILAGAAAEVDDSKLSAFFKEIEGKDVAELIAEGNAKLASVPSGGGGGGGGGGDGGGDAGGAAAAAAPEAEEEEEADMDFELVRLIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7U0</accession>
    <name>A4S7U0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA methyltransferase 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_27615</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421512.1">
        <property type="nucleotide sequence ID" value="XM_001421475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7U0"/>
    <dbReference type="STRING" id="436017.A4S7U0"/>
    <dbReference type="GeneID" id="5005230"/>
    <dbReference type="Gramene" id="ABO99805">
        <property type="protein sequence ID" value="ABO99805"/>
        <property type="gene ID" value="OSTLU_27615"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27615"/>
    <dbReference type="eggNOG" id="KOG0838">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_5_1_1"/>
    <dbReference type="OMA" id="QVPPYEY"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SpoU_methylase"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00034881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="318" mass="33744" checksum="9C529608A8963C44" modified="2007-05-15" version="1">MRAGEASYDGFGEAPRGRLAREGAEDARRRGRGSEREARYDRAAARRERGVAPTIAEGLVGEIVYGTNPVLEALRRNRRALFALYVQTGEGGAANGGKGAGAESEILRLAEARAVTVKRASKHDLNMACDNKPHQGVLLDAEALEIPTLEDLPKWDGRGEPPVWLALDEIVDPQNLGAALRSAHFLGVDGVVCCAKNSAPFNATVSKASAGAMEAQVVHQTGVMHRFLAKARDEGWDVVGAAADARAEDVSDFSVRAPTILVMGNEGSGLRTNVRRACNRLIEIPRSASSAAGVDSLNVSVAAGILIHRLVAARRSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S876</accession>
    <name>A4S876_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="172"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
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        <location>
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            <end position="498"/>
        </location>
    </feature>
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            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP00008.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="557" mass="61486" checksum="6548E6CA299FFE9F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8N7</accession>
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        <recommendedName>
            <fullName evidence="7">Importin N-terminal domain-containing protein</fullName>
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    </protein>
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        <name evidence="8" type="ORF">OSTLU_25624</name>
    </gene>
    <organism evidence="8 9">
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            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="protein sequence ID" value="ABO99950"/>
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    </dbReference>
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    <dbReference type="eggNOG" id="KOG1991">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004196_3_0_1"/>
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    <dbReference type="OrthoDB" id="760868at2759"/>
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        <property type="component" value="Chromosome 15"/>
    </dbReference>
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        <property type="term" value="C:cytosol"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM-like"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="743" mass="83897" checksum="DDA89967D8F4DA39" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9D7</accession>
    <name>A4S9D7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DMT family transporter: UDP-galactose/UDP-glucose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_37524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421918.1">
        <property type="nucleotide sequence ID" value="XM_001421881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9D7"/>
    <dbReference type="GeneID" id="5005947"/>
    <dbReference type="Gramene" id="ABP00212">
        <property type="protein sequence ID" value="ABP00212"/>
        <property type="gene ID" value="OSTLU_37524"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37524"/>
    <dbReference type="eggNOG" id="KOG1581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036019_3_0_1"/>
    <dbReference type="OMA" id="KIMTQHY"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF13">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="316" mass="35117" checksum="2119295C1F674213" modified="2007-05-15" version="1">MQSQTQMTRIAMCVVGVVGSLIVYGILQERIMTRPYGVESEYFKYSVFLVLSNRVLSASLAAAILAYTKGMVQPAAPIWKYAGVSASNVLATTCQYEALRYVSFPVQTLGKCAKMIPVMIWGYFINQRRYTLNDYVIASCVTLGCTIFALYGDLTHKHSAKSSNTSAKGLMLMLGYLGFDGFTSTFQDKLFKGYQMETYNQMLYVNGVSACLSVAWLLSDGAIWQALEFIARHPAVLSDIITLSLSSMFGQLCILYTIKEFGALLFAAIMTTRQLLSILLSCVLFLHPLTWQQWCGTALVFSALYAQAYLKNAQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9H5</accession>
    <name>A4S9H5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422067.1">
        <property type="nucleotide sequence ID" value="XM_001422030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9H5"/>
    <dbReference type="GeneID" id="5005981"/>
    <dbReference type="Gramene" id="ABP00361">
        <property type="protein sequence ID" value="ABP00361"/>
        <property type="gene ID" value="OSTLU_28203"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28203"/>
    <dbReference type="HOGENOM" id="CLU_534634_0_0_1"/>
    <dbReference type="OrthoDB" id="10486065at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="510" mass="55408" checksum="929E57BB5B9EE905" modified="2007-05-15" version="1">MSRANANAIANAKARDVDAGTSRARALEATLESARDAVATTSDGVTAFAEASIVNSRDVSDVRARETKEHERESAREASAAIVRRPTPTGKVDVSRQEMLEALARELDETESLLGTTKRTTEGERAMSVASLFAGGERYVAATSFATTSRREEARGGAEAAPSETLGRESRRWVQPLKRARWSAITMVMCACACVAALMFAGETPQARARRHIHLSSLSDMLCEVAFTPAIAEASNDTPINRVIAATDQIYILTTQNCASVNTTIRVPKEFEGKATCVSGKVLDRCTAASTGVWYKSHYTRVSMSHGMIAKHAKENGFEHITVMEEDAVVNADVEVHSETEADLLTLIGGEFEGESASLGRVKLGSGGGGPPAWKLIRPSVRPHLFEKFEIKKSSTGGMVEVTTATRDDLVCPTQCHCVNTRAEGQLCRLNAGGCDLRSSDMYLLHNTAYDELISVLFTGTDDTIIDHYVLQNVDSAWLVHPSITTQAKLDIDRALQHRVQELFEEKCVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9J5</accession>
    <name>A4S9J5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRP15-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422078.1">
        <property type="nucleotide sequence ID" value="XM_001422041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9J5"/>
    <dbReference type="STRING" id="436017.A4S9J5"/>
    <dbReference type="GeneID" id="5006239"/>
    <dbReference type="Gramene" id="ABP00395">
        <property type="protein sequence ID" value="ABP00395"/>
        <property type="gene ID" value="OSTLU_28223"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28223"/>
    <dbReference type="eggNOG" id="KOG2974">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1075159_0_0_1"/>
    <dbReference type="OMA" id="RGHVKPQ"/>
    <dbReference type="OrthoDB" id="20949at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012459">
        <property type="entry name" value="Rrp15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245:SF14">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07890">
        <property type="entry name" value="Rrp15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="202"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29694" checksum="3C54C4C1338CDF16" modified="2007-05-15" version="1">MKEREDASDDDDDATSESRSRDDDDEEEEESSSESFDDDEFVQDEDEDEAEDEDESQGEDDDDSEEEEDEALARPVSNAMLGMSRAFQSLVGDDEDEDETTAMLPKSRKQRADELEAKAEEKERRAIKRAKLEVKQRGHVKPQPRGRDVESDMLERRLHNTATKGVVRLFKAVGKAQQDAEKAKTMRRKDALISKAKFLEELRGEKKSKHDADEKSTSKASFLHNDFMLDAGKKMKDWDREQSAAPKDLEYDEDEDDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9J8</accession>
    <name>A4S9J8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_10211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9J8"/>
    <dbReference type="STRING" id="436017.A4S9J8"/>
    <dbReference type="GeneID" id="5006138"/>
    <dbReference type="Gramene" id="ABP00500">
        <property type="protein sequence ID" value="ABP00500"/>
        <property type="gene ID" value="OSTLU_10211"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10211"/>
    <dbReference type="eggNOG" id="KOG1109">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033298_1_0_1"/>
    <dbReference type="OMA" id="TMNASIN"/>
    <dbReference type="OrthoDB" id="2016540at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="292" mass="32685" checksum="48E887BE71710518" modified="2007-05-15" version="1" fragment="single">VEWGLWWVALGVSSSIGFGSGMHTGLLFLFPHILKVCQTVELCGNVDFDTRRNIWFMMPTEELFECASKPRARGVSYVDIWLSVLPECVAWGVGTAFGEIPPYWVSYFAAKAGRENKELSDITHVDASDMDQVQKKIHGFKLWMIAFMKRYGFLGLLAMSSWPNAAFDLCGVCCGSFMMPFWLFITATTMGKGFVKSPVQGLVLTSLFYKNSREKIIAFFSGWLPASWEVDRTMNASINSMLQKVLASGRAGKKTRNTLALAVSPSKLWGHFVTALVAYFLLSCLEEIARME</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
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    <name>A4S9K7_OSTLU</name>
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            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_18645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422187.1">
        <property type="nucleotide sequence ID" value="XM_001422150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9K7"/>
    <dbReference type="STRING" id="436017.A4S9K7"/>
    <dbReference type="GeneID" id="5006244"/>
    <dbReference type="Gramene" id="ABP00504">
        <property type="protein sequence ID" value="ABP00504"/>
        <property type="gene ID" value="OSTLU_18645"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SUAR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1597224_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF14">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
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    </dbReference>
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
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    </dbReference>
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    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="167" mass="18653" checksum="2DF7F8AD70D2EACF" modified="2007-05-15" version="1">MGDNLLSSAAAFDDHVFVGCEVHRPGVAQALMGIEARGLGDRVKVSRADGLWVLDAYATARSLDEVACHFPDPWRGESKAHRRLVNPLLFVLLERALRPGGRLSVATDDAEYAEHVRRVFRDFAQPRGWARCDAFARFDSKYSLKASEEGRECVDFRFRFPGSIDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9M6</accession>
    <name>A4S9M6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422093.1">
        <property type="nucleotide sequence ID" value="XM_001422056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9M6"/>
    <dbReference type="GeneID" id="5006255"/>
    <dbReference type="Gramene" id="ABP00410">
        <property type="protein sequence ID" value="ABP00410"/>
        <property type="gene ID" value="OSTLU_93920"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93920"/>
    <dbReference type="HOGENOM" id="CLU_289253_0_0_1"/>
    <dbReference type="OMA" id="WRNERAK"/>
    <dbReference type="OrthoDB" id="10512437at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="982"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1061" mass="114635" checksum="2ED0F4B4308DE048" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA52</accession>
    <name>A4SA52_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18791</name>
    </gene>
    <organism evidence="1 2">
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        <lineage>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422287.1">
        <property type="nucleotide sequence ID" value="XM_001422250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA52"/>
    <dbReference type="STRING" id="436017.A4SA52"/>
    <dbReference type="GeneID" id="5006361"/>
    <dbReference type="Gramene" id="ABP00604">
        <property type="protein sequence ID" value="ABP00604"/>
        <property type="gene ID" value="OSTLU_18791"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18791"/>
    <dbReference type="HOGENOM" id="CLU_501954_0_0_1"/>
    <dbReference type="OrthoDB" id="419709at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="543" mass="63363" checksum="AA94B771B618A69E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAC8</accession>
    <name>A4SAC8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422364.1">
        <property type="nucleotide sequence ID" value="XM_001422327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAC8"/>
    <dbReference type="GeneID" id="5006422"/>
    <dbReference type="Gramene" id="ABP00681">
        <property type="protein sequence ID" value="ABP00681"/>
        <property type="gene ID" value="OSTLU_28524"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28524"/>
    <dbReference type="HOGENOM" id="CLU_1144167_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="27347" checksum="3C3B457C623CD09D" modified="2007-05-15" version="1">MTCYELESRERHKKPKIWNGDGVEGKQAIGRARCAVREAARAVRDGCHGDKLLHMCWNNKSWNVLNDDVLLEAARCGNRECAQTIAEHHHHGEGLTKEGVMRASFAAAESGHYDIVEMLSDSIAFDLSCSLSTAHYEIALASKNAEFVWRLIRAEAPMACSQMEDVTDLVVSHYTGAIADERERLQIEMMMMKYVENCLDDGSAEWDSQTPTPELDLDSGVDAYETEDAIGNDEKEYTAREWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAR2</accession>
    <name>A4SAR2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_43847</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422480.1">
        <property type="nucleotide sequence ID" value="XM_001422443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAR2"/>
    <dbReference type="STRING" id="436017.A4SAR2"/>
    <dbReference type="GeneID" id="5006538"/>
    <dbReference type="Gramene" id="ABP00797">
        <property type="protein sequence ID" value="ABP00797"/>
        <property type="gene ID" value="OSTLU_43847"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43847"/>
    <dbReference type="eggNOG" id="KOG1372">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_14_1_1"/>
    <dbReference type="OMA" id="AFRDWSH"/>
    <dbReference type="OrthoDB" id="10253554at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05260">
        <property type="entry name" value="GDP_MD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000924">
        <property type="entry name" value="GDP-mannose 4,6 dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715:SF1">
        <property type="entry name" value="GDP-MANNOSE 4,6 DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="GDP-MANNOSE 4,6-DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="5">
        <location>
            <begin position="16"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="362" mass="41009" checksum="5C1D1AFAED4C675B" modified="2007-05-15" version="1">MQAGLSDGDRARKVAFITGVTGQDGSYLVELLLSKGYTVHGIKRRSSSYNHPRLEHIMEPGYPNGQNFFLHYGDLTDLHALVAICRDVRPTEVYNLAAQSHVQVSFQMPMYTAEVDGVGTLNLLEAIRLSGQEKTARFYQASTSELYGKVQEIPQSEKTPFYPRSPYAVAKMMAFWAVVNYRESYDMYACNGILFNHESPRRGETFVTRKITLAVANIKAGKQECLYLGNMDAKRDWGHARDYVECMWKMLQQDTPEDFVVATGETNTVRHFVDRAFDVAGMKLKFEGEGVDEVGIEIATGRTLVRVHERYFRPAEVDLLIGDPSKALNKLKWNPRTTSLEELIKEMVEADIARIENPGLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB52</accession>
    <name>A4SB52_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_19051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422555.1">
        <property type="nucleotide sequence ID" value="XM_001422518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB52"/>
    <dbReference type="GeneID" id="5006774"/>
    <dbReference type="Gramene" id="ABP00872">
        <property type="protein sequence ID" value="ABP00872"/>
        <property type="gene ID" value="OSTLU_19051"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19051"/>
    <dbReference type="HOGENOM" id="CLU_048660_0_0_1"/>
    <dbReference type="OMA" id="GDCITRC"/>
    <dbReference type="OrthoDB" id="498022at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="428" mass="45445" checksum="2C05E8B254E938F1" modified="2007-05-15" version="1">MRRALDDDDDLGGARRRRDGARARAGARTSAAKADGDGCAARGASAAAREENGGAAAPGEGEGAGGAMRVAREWVGGDGAKARARGVGSGGAARRAARGLNIATTTAVGMYVYWILMGTVAWISHLGERAPWLRFALPAEGYPGNAPSSAGALGFVARNVPLSLIFVVPHSVFLPSRLRKIFGKHGRLMYNFVSAATLHFFLLNFTPLKTPVVMTIPFNTNFHNALSIGCLAYASYAFLSSPATLGLLGVSSALELRDSKYSNPAAGMDAITWMGVTTWRLGGASAFVLFTGLSIIPRELTLGDCITRCVAAVYLRQRSRSFREWVEKIEGVHLLTWILRGTLLSFACHGALQGGGNVRTVGWILFGAASLAGILRLAESESPNAKKKPISRAASFDVAEAAPAALDDVARVNRPERWHAWNPHARMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBH6</accession>
    <name>A4SBH6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_8844</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422620.1">
        <property type="nucleotide sequence ID" value="XM_001422583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBH6"/>
    <dbReference type="STRING" id="436017.A4SBH6"/>
    <dbReference type="GeneID" id="5006678"/>
    <dbReference type="Gramene" id="ABP00937">
        <property type="protein sequence ID" value="ABP00937"/>
        <property type="gene ID" value="OSTLU_8844"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8844"/>
    <dbReference type="eggNOG" id="KOG0419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_10_2_1"/>
    <dbReference type="OMA" id="DHKSQYI"/>
    <dbReference type="OrthoDB" id="9984419at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000004">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="149" mass="16581" checksum="E45D169FA0319F00" modified="2007-05-15" version="1" fragment="single">MSTPARKRLMRDFKRLQTDPPAGISGTPSESNIMAWHAVIFGPEGTPWEGGTFKLTIAFSEEYPNKAPVVKFVTKMFHPNVYNDGSICLDILQNQWSPIYDVGAILTSIQSLLCDPNPNSPANSEAAALYNENRRAYNKRVSACVEDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQG7</accession>
    <name>A4RQG7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L3, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL3</name>
        <name evidence="6" type="ORF">OSTLU_23838</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415385.1">
        <property type="nucleotide sequence ID" value="XM_001415348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQG7"/>
    <dbReference type="STRING" id="436017.A4RQG7"/>
    <dbReference type="GeneID" id="4999434"/>
    <dbReference type="Gramene" id="ABO93677">
        <property type="protein sequence ID" value="ABO93677"/>
        <property type="gene ID" value="OSTLU_23838"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_23838"/>
    <dbReference type="eggNOG" id="KOG0746">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033361_2_1_1"/>
    <dbReference type="OMA" id="QRTEYNK"/>
    <dbReference type="OrthoDB" id="1611972at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000079">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1430.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000351">
        <property type="entry name" value="Ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="entry name" value="Ribosomal protein L3, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="386" mass="43735" checksum="8E2B8B6CB4829299" modified="2007-05-15" version="1">MSHRKFEHPRYGNLGFLPKKRSKRSRGKVKSFPKDDASKPPHLTAFMGFKAGMTHIVRDVDKPGSKMHKKETCESVTIIECPELIVVGLVGYVRTPKGLRGKKTVWAEHLNDEVRRRFYKNWFKSKKKAFTKYTKNYTNGSIDKDLDELKKSCDVIRVIAHTQVRKVSGLKQKKAHIMEIQVNGGDVAAKVDFGYALFEKAVPVDTVFQQDEMIDLIGVTKGKGYEGVVTRWGVTRLPRKTHRGLRKVGCIGAWHPSRVSYTVARAGQHGYHHRTEINKKVYKIGKAGQDSFGASTFHDPTEKEITPMGGFAHYGIVKHDYVMIKGGVVGPRKRLITMRQSLFKQTRRVATEKITLKFIDTSSKFGHGRFQTSEEKAKVFGTTKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQJ3</accession>
    <name>A4RQJ3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ZIP family transporter: zinc ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_86026</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
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                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">CCE9901</strain>
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    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="gene ID" value="OSTLU_86026"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="ZIP"/>
    </dbReference>
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        <property type="entry name" value="OS05G0316100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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    <sequence length="554" mass="57132" checksum="17422C1B969CB5DA" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
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            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
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                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
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            <strain evidence="2 3">CCE9901</strain>
        </source>
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            <begin position="159"/>
            <end position="176"/>
        </location>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQQ4</accession>
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        <recommendedName>
            <fullName evidence="4">OCEL domain-containing protein</fullName>
        </recommendedName>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
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                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        </location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="36221" checksum="BC7A5F38FF5746AE" modified="2007-05-15" version="1">MRGEEELREKRERHLKVVEVDEVAGREGASAATSDGLRRDLERWSRVVAAAMLDGSGSEFSRVKAAVMSLLFERPLSENAIRDCVAKGFALACKPPPNQRVVRETIKHVAQLRPPGRYELVDGKRRDAQKSHAQLTAAAKHIKLPKKEKAAAAPPCAPSQPTSTQATNGTSVPTPPLQEPPRVLRNGITVDLGDRSPSIDLDPHAHVFARRPPAKTREIAPRAAGDDDDDWRHLTPSPTVDVIESHDECEALKATYDTKYDTYVSLHARLAANADEYEALRRGDDAAALLPRFASLRRERYAAMRDVFDGLHDELLRIRVAIDAFASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQT8</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">OSTLU_13669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Chlorophyta</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQT8"/>
    <dbReference type="GeneID" id="4999826"/>
    <dbReference type="Gramene" id="ABO94084">
        <property type="protein sequence ID" value="ABO94084"/>
        <property type="gene ID" value="OSTLU_13669"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13669"/>
    <dbReference type="HOGENOM" id="CLU_765898_0_0_1"/>
    <dbReference type="OrthoDB" id="10625476at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="362" mass="38860" checksum="C2510B701217C2D9" modified="2007-05-15" version="1">MTARDGGVEAENVARVRESSQSAEGASTANGARARLGLGAAKAWLAGKASRAKIAVRAKTKAVVRRVKLELREQFPPPDVWFEHMERLEEVAAFEAAERERATAVVESSSDGVGAATSTPEDVGEPEASVASVAGSEDVIDASADVEELNLDFERCALSPCEASTSYDENDYVFDEEDGDDHGTDEHRVVVVPRALALDGALPQSNTVSFVPPPKALKLTGKVIDSSKANTFWAGARSRTGFDFSRDAPVVRVTPSSPASPECPIPSPPHAEKTAHAETPPWYLKRLDRESRELAKTARTLIDWTTDLFDVSAPDADAPTTESHLDADVTVNSKTKMENVWINVGECDLVIAVPSSNCEKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR12</accession>
    <name>A4RR12_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_39516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415824.1">
        <property type="nucleotide sequence ID" value="XM_001415787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR12"/>
    <dbReference type="STRING" id="436017.A4RR12"/>
    <dbReference type="GeneID" id="5000014"/>
    <dbReference type="Gramene" id="ABO94116">
        <property type="protein sequence ID" value="ABO94116"/>
        <property type="gene ID" value="OSTLU_39516"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39516"/>
    <dbReference type="eggNOG" id="KOG4777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2892759_0_0_1"/>
    <dbReference type="OrthoDB" id="1894490at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46278:SF2">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46278">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="63" mass="6918" checksum="9F2C379DA8F21FC8" modified="2007-05-15" version="1" fragment="single">ETIARRRVTACLDATDNDDVYVGRIRQDISQPNNKGLDLFVCGDQIKKGAALNAVQCAELLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRB0</accession>
    <name>A4RRB0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415868.1">
        <property type="nucleotide sequence ID" value="XM_001415831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRB0"/>
    <dbReference type="STRING" id="436017.A4RRB0"/>
    <dbReference type="GeneID" id="4999641"/>
    <dbReference type="Gramene" id="ABO94160">
        <property type="protein sequence ID" value="ABO94160"/>
        <property type="gene ID" value="OSTLU_28952"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28952"/>
    <dbReference type="eggNOG" id="ENOG502SVST">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163596_0_0_1"/>
    <dbReference type="OMA" id="MLIGSEW"/>
    <dbReference type="OrthoDB" id="10249250at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002124">
        <property type="entry name" value="Cyt_c_oxidase_su5b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01215">
        <property type="entry name" value="COX5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51359">
        <property type="entry name" value="COX5B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="124" mass="13568" checksum="BBC14E83A33C1C28" modified="2007-05-15" version="1">MLRRSIMAVTRRRVEAALGTSARAYSGGGVVTNLENATGLYKAELEGRLKGEDIFDHHAFLRAPTGTKESPCVVESTMEYRVVGSPDPDDDSIIHWGRLEEGAPPMLIGSEWFVHKRVPGGGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRF3</accession>
    <name>A4RRF3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-ascorbate peroxidase</fullName>
            <ecNumber evidence="3">1.11.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_6186</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415890.1">
        <property type="nucleotide sequence ID" value="XM_001415853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRF3"/>
    <dbReference type="STRING" id="436017.A4RRF3"/>
    <dbReference type="GeneID" id="4999831"/>
    <dbReference type="Gramene" id="ABO94182">
        <property type="protein sequence ID" value="ABO94182"/>
        <property type="gene ID" value="OSTLU_6186"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6186"/>
    <dbReference type="eggNOG" id="ENOG502QS7Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036959_3_0_1"/>
    <dbReference type="OMA" id="QRKWNGP"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016688">
        <property type="term" value="F:L-ascorbate peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="6">
        <location>
            <begin position="81"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="30104" checksum="D217681EEC220AE6" modified="2007-05-15" version="1" fragment="single">LEGAREAAFAMLDARKCHPIMVRLAWHDAGTFDATAADAWPRCGGANGSIRFDAELAHGANAGLKKALGYAREIVERFPALSHADAIQLCGACAIESAGGPRIPMKYGRKDSDEPAREGNLPDAEAPFGDGSKTPGEHLRRVFGRLGFDDREIVALSGAHTIGRAFKERSGTTEYGYGVKNATKYTGGCPFSPKGDGDGDFGMPGGASWTSCWLKFDNSYFTEGGSDDKNLLWLSTDRVLHTDPGFAPHFMRYARDQDAFFFEFAQAFAKLSECGARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRZ0</accession>
    <name>A4RRZ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_3025</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415989.1">
        <property type="nucleotide sequence ID" value="XM_001415952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRZ0"/>
    <dbReference type="STRING" id="436017.A4RRZ0"/>
    <dbReference type="GeneID" id="4999828"/>
    <dbReference type="Gramene" id="ABO94281">
        <property type="protein sequence ID" value="ABO94281"/>
        <property type="gene ID" value="OSTLU_3025"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3025"/>
    <dbReference type="eggNOG" id="KOG0731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_21_3_1"/>
    <dbReference type="OMA" id="ARANDNM"/>
    <dbReference type="OrthoDB" id="498030at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000277">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF110">
        <property type="entry name" value="INACTIVE ATP-DEPENDENT ZINC METALLOPROTEASE FTSHI 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="36"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="247" mass="26402" checksum="B1A0EC49E631E0A2" modified="2007-05-15" version="1" fragment="single">VTFADVAGVQEAKAELFELVQIMKNAEKYKNVRGRLPTGCLLVGPPGTGKTLLARAVAGESGVAFFPVAASEFVELFVGRGAARVRELFAEARKARPAIIFIDELDAVGSRRGAGLNEERDQTLNQLLVEMDGFAKDSGILILAATNRPDALDPALLRPGRLTRRVFVGPPTQQGRAQILSVHLRGLDLEEDVDVVCDVISRATPGFTGAELANVANEAALLSVRDGRQLVSIDDMLDGVSRTKDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="109" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS62</accession>
    <name>A4RS62_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HFO3502</name>
        <name evidence="12" type="ORF">OSTLU_14029</name>
        <name evidence="13" type="ORF">OSTLU_44220</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the histone H4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416024.1">
        <property type="nucleotide sequence ID" value="XM_001415987.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420335.1">
        <property type="nucleotide sequence ID" value="XM_001420298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS62"/>
    <dbReference type="SMR" id="A4RS62"/>
    <dbReference type="STRING" id="436017.A4RS62"/>
    <dbReference type="GeneID" id="4999439"/>
    <dbReference type="GeneID" id="5004392"/>
    <dbReference type="Gramene" id="ABO94316">
        <property type="protein sequence ID" value="ABO94316"/>
        <property type="gene ID" value="OSTLU_14029"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO98628">
        <property type="protein sequence ID" value="ABO98628"/>
        <property type="gene ID" value="OSTLU_44220"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14029"/>
    <dbReference type="KEGG" id="olu:OSTLU_44220"/>
    <dbReference type="eggNOG" id="KOG3467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109117_2_3_1"/>
    <dbReference type="OMA" id="RRNRNMS"/>
    <dbReference type="OrthoDB" id="529151at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000002">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 9" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-T/Histone H4 histone fold" evidence="11">
        <location>
            <begin position="44"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF15511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO98628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="103" mass="11395" checksum="A9FD4E5AF8B97598" modified="2007-05-15" version="1">MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSM1</accession>
    <name>A4RSM1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Rpl35p</name>
        <name evidence="6" type="ORF">OSTLU_119658</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416468.1">
        <property type="nucleotide sequence ID" value="XM_001416431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSM1"/>
    <dbReference type="STRING" id="436017.A4RSM1"/>
    <dbReference type="GeneID" id="5000284"/>
    <dbReference type="Gramene" id="ABO94761">
        <property type="protein sequence ID" value="ABO94761"/>
        <property type="gene ID" value="OSTLU_119658"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119658"/>
    <dbReference type="eggNOG" id="ENOG502SCTD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160310_0_0_1"/>
    <dbReference type="OrthoDB" id="162638at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.60:FF:000001">
        <property type="entry name" value="50S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_bL35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_bL35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_bL35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="129" mass="14010" checksum="BCFD66D8CF243F23" modified="2007-05-15" version="1">MISFQSAATIPRLTGAKAAHTARSQTGSNRALTFCSSLVGTRVVAKPRGEPERKQFFVAASKMKTRKAAAKRYKVTASGKVLHRRPGKAHLNGPKPTTRKARLSHLRQVGTSQLSLVAATMPYSKIKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP1</accession>
    <name>A4RSP1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoporin NSP1-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Nup62</name>
        <name evidence="2" type="ORF">OSTLU_119630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416456.1">
        <property type="nucleotide sequence ID" value="XM_001416419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP1"/>
    <dbReference type="STRING" id="436017.A4RSP1"/>
    <dbReference type="GeneID" id="5000418"/>
    <dbReference type="Gramene" id="ABO94749">
        <property type="protein sequence ID" value="ABO94749"/>
        <property type="gene ID" value="OSTLU_119630"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119630"/>
    <dbReference type="HOGENOM" id="CLU_1550109_0_0_1"/>
    <dbReference type="OMA" id="HTEERFA"/>
    <dbReference type="OrthoDB" id="10431131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007758">
        <property type="entry name" value="Nucleoporin_NSP1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05064">
        <property type="entry name" value="Nsp1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoporin NSP1-like C-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="173" mass="19430" checksum="B1D661AF0CDEED1F" modified="2007-05-15" version="1">MTRGTEDLIRGWQSGLAATNETFSRQTRVLNSLDTTLSRQRKSINSIQTDLCGLSAAQYRLKFQLETLENYQSDLEVALAKIEEDTHELVRHGPGAVQLDRNDRLFCFAESMSAQLKDVCEKIQDVSSITWFIPITQSDQEGSSSLSKYVNILNRQLATLKSLEGEIAQLSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSR1</accession>
    <name>A4RSR1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-adaptin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Bad</name>
        <name evidence="8" type="ORF">OSTLU_119607</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Adaptor protein complexes are heterotetramers composed of two large adaptins (beta-type subunit and alpha-type or delta-type or epsilon-type or gamma-type subunit), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416201.1">
        <property type="nucleotide sequence ID" value="XM_001416164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSR1"/>
    <dbReference type="STRING" id="436017.A4RSR1"/>
    <dbReference type="GeneID" id="5000155"/>
    <dbReference type="Gramene" id="ABO94494">
        <property type="protein sequence ID" value="ABO94494"/>
        <property type="gene ID" value="OSTLU_119607"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119607"/>
    <dbReference type="eggNOG" id="KOG1061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006320_4_0_1"/>
    <dbReference type="OMA" id="NPPEVQW"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="16"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="551" mass="62290" checksum="831BF14BE2085D5B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSU3</accession>
    <name>A4RSU3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein bem46-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Bem46</name>
        <name evidence="2" type="ORF">OSTLU_119577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416187.1">
        <property type="nucleotide sequence ID" value="XM_001416150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSU3"/>
    <dbReference type="STRING" id="436017.A4RSU3"/>
    <dbReference type="GeneID" id="5000096"/>
    <dbReference type="Gramene" id="ABO94480">
        <property type="protein sequence ID" value="ABO94480"/>
        <property type="gene ID" value="OSTLU_119577"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119577"/>
    <dbReference type="eggNOG" id="KOG4391">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_2_1_1"/>
    <dbReference type="OMA" id="WLPEQGY"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="289" mass="32464" checksum="6CA3AB079561F169" modified="2007-05-15" version="1">MIRLVTDIANKSLLILSCSYAAILGALCLFQRKLQYFPTAEVPTLDSLPTAFRRVEEFEVHVIDGLKLKGWLWRQKSSPVLILHLHGNAGNRFHRLYWANEIVKRTSCSVALFDYRGFGGNPGRISEDGLIKDAVAAITWAYTNAKRNSQKLVLHLESIGSAVGLSALLKMAVEVRVDGIVVEGGLCSCYDLARSMLPFVPVKLLLRDKWNLTIQGAQELDEDINFLSLHGKADRIVPLWCGTKLFEAVSCRHKKFIAFEFGDHNDLIIQPGYLDALLEFYAEVERKDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT43</accession>
    <name>A4RT43_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTV1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416136.1">
        <property type="nucleotide sequence ID" value="XM_001416099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT43"/>
    <dbReference type="STRING" id="436017.A4RT43"/>
    <dbReference type="GeneID" id="5000448"/>
    <dbReference type="Gramene" id="ABO94428">
        <property type="protein sequence ID" value="ABO94428"/>
        <property type="gene ID" value="OSTLU_29999"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29999"/>
    <dbReference type="HOGENOM" id="CLU_029233_1_0_1"/>
    <dbReference type="OrthoDB" id="5852896at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007307">
        <property type="entry name" value="Ltv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531">
        <property type="entry name" value="LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531:SF0">
        <property type="entry name" value="PROTEIN LTV1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="457" mass="51426" checksum="D62A19D0F5EE7B43" modified="2007-05-15" version="1">MGGRKKTSFVDKKSAVTYALLPNHDRQAHSLGLPNTWVRTDNNQGADPFDDGDHVGRELERELRESHSQHVSAGDLSNEKDTNNKLTASEKLELGLPDDGYDYTKHLRECDPDKVRTVESDYANPRSEIFTKSIDHARTEYAGGAMNQGECDFHTLHEQDNIADVLQLLDDISQGGSMETCAYEELQDDIIFLASQRKSEERCSSPFLPRKVEPLSPQTHRAATKVLVRSSSDAVGNERSDDSHFLRMIHNYDDDDLGATPMKDESNIRSENTKWQTLEQLNFNDGNLQKHNVDARTVKSYALNHSEEQTPRNAYLEESILDKRTQATHMYDCESILSLHSNSNHHPKLLEGRLLSEERKLKTPDQQSASIPGIHTCFPLGMKASSEAEFDWRSCTARKGESAQQKKERKNAVKMGRRQARSTKKGLKESFQYFKQAGAGGGSSGDVRAKISVTKMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTE7</accession>
    <name>A4RTE7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_48805</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416089.1">
        <property type="nucleotide sequence ID" value="XM_001416052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTE7"/>
    <dbReference type="STRING" id="436017.A4RTE7"/>
    <dbReference type="GeneID" id="5000548"/>
    <dbReference type="Gramene" id="ABO94381">
        <property type="protein sequence ID" value="ABO94381"/>
        <property type="gene ID" value="OSTLU_48805"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48805"/>
    <dbReference type="eggNOG" id="KOG1027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Chromosome 2"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Putative Serine/threonine-protein kinase/endoribonuclease IRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="KEN_sf"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
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        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51392">
        <property type="entry name" value="KEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="8" id="KW-0418">Kinase</keyword>
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    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="15"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="KEN" evidence="14">
        <location>
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            <end position="387"/>
        </location>
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        <location>
            <begin position="420"/>
            <end position="448"/>
        </location>
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            <begin position="420"/>
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        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50103"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS51392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO94381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="457" mass="51214" checksum="AC2C5AD9141A896D" modified="2007-05-15" version="1">MEEKTREETRVGRLRIKPSVLGYGSCGTIVFEGELDGRRVAVKRLLAQFHELARKELQALIASDEHPNILRCFALEEDSNFVYMALELCASILHDVVAGLAALHGQGIIHRDLKPQNVLITSSGRGKIADMGLAKRVNVSEGTSFYTHTNGNLNVNDAAGTSGWQAPERLTQGRQSRSVDVFSLGCLMYYCLTGGAHPFGERLQRDANVVANSYDVSKLKYFPEAEALVKACIDADPSKRPSATEILAHPMWWDAEKKLQFLIDASDRVELEDRMSDRSLLRAFETRAKSSIACDDWTKKLDAALLENLGRYREYDGTSLRDLLRVIRNKANHYRELPPKLQRTLGSYPDGLWRYVSIRFPALLLGVRDFFAPSAAREPTLAKYFLSIDAASKASFAPPLARAESIPDKPLIAPQVFPSRPGREPCEFYMKTGRCKFGATCKFDHPQGVHWDVHNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU22</accession>
    <name>A4RU22_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416847.1"/>
    </dbReference>
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        <property type="gene ID" value="OSTLU_14511"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14511"/>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="166" mass="17963" checksum="DAC023B579B058FE" modified="2007-05-15" version="1">MASASADTLARDSVVTSPTSDLLVLSRDDERISTTPTSEATTTASPCTVTLMSPSVFLASHEEMFPCDLVDLINMLNDSDSDVESGSAAAPSSSSSVARSHEYSSSIANNGKGKSSYWQNQALCSPARRAFWCGDSCRLPDAREISRRLDELNAQYVLRVRSMRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUD7</accession>
    <name>A4RUD7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416941.1">
        <property type="nucleotide sequence ID" value="XM_001416904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUD7"/>
    <dbReference type="GeneID" id="5000989"/>
    <dbReference type="Gramene" id="ABO95234">
        <property type="protein sequence ID" value="ABO95234"/>
        <property type="gene ID" value="OSTLU_30585"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30585"/>
    <dbReference type="eggNOG" id="ENOG502S3IU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082859_1_0_1"/>
    <dbReference type="OMA" id="VRCETEE"/>
    <dbReference type="OrthoDB" id="185493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26038" checksum="FFD89A70053D2959" modified="2007-05-15" version="1">MGRGDDGGTETRASDDGGTGTRAASVRAGTIAREDVVHSRYLTVYDREIEFADEDGTTRSFAYDVVGHPRSEFRFVCVAPFHSRERTVSGEPEFTIIREYAQGSNSECVVLPSGCFEPGKHESLDEVAREELQQESRLRGGTLMSLLDDDNPGLLETKWCRNRCFPFLNIDGEECNEGERDAEEFNMTHERVTARELKRLMYGGVMMMPSVVTAQLAIDKLMTTGHLNLDDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUG3</accession>
    <name>A4RUG3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cullin family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_33783</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the cullin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416954.1">
        <property type="nucleotide sequence ID" value="XM_001416917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUG3"/>
    <dbReference type="STRING" id="436017.A4RUG3"/>
    <dbReference type="GeneID" id="5000675"/>
    <dbReference type="Gramene" id="ABO95247">
        <property type="protein sequence ID" value="ABO95247"/>
        <property type="gene ID" value="OSTLU_33783"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33783"/>
    <dbReference type="eggNOG" id="KOG2166">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004747_7_1_1"/>
    <dbReference type="OMA" id="MFKDMTI"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000001">
        <property type="entry name" value="Cullin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000002">
        <property type="entry name" value="cullin-3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="7">
        <location>
            <begin position="428"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="786" mass="89757" checksum="8AED6F7C53BB4FAF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUI9</accession>
    <name>A4RUI9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GTPase Obg</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_45203</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416679.1">
        <property type="nucleotide sequence ID" value="XM_001416642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUI9"/>
    <dbReference type="STRING" id="436017.A4RUI9"/>
    <dbReference type="GeneID" id="5000847"/>
    <dbReference type="Gramene" id="ABO94972">
        <property type="protein sequence ID" value="ABO94972"/>
        <property type="gene ID" value="OSTLU_45203"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45203"/>
    <dbReference type="eggNOG" id="KOG1489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011747_2_1_1"/>
    <dbReference type="OMA" id="HVQRCRV"/>
    <dbReference type="OrthoDB" id="347018at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009416">
        <property type="term" value="P:response to light stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.210.12:FF:000001">
        <property type="entry name" value="GTPase Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="entry name" value="GTP-binding protein OBG, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008954">
        <property type="entry name" value="PRK12296.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008955">
        <property type="entry name" value="PRK12297.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008956">
        <property type="entry name" value="PRK12299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF44">
        <property type="entry name" value="GTP-BINDING PROTEIN OBGC, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09269">
        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="Obg GTP-binding protein C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="9">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="7">
        <location>
            <begin position="160"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="8">
        <location>
            <begin position="345"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="49663" checksum="259D6F34C9365D24" modified="2007-05-15" version="1">MRCFDTAKIYVKAGDGGDGQVAFRREKFVPQGGPSGGNGGIGGAVYIVADKNMNSLDGFRKKVHHRAEAGKRGLGSKCAGRNGRDLEILVPPGTIIRDSRSKTIIAEITKAEQRVMVLAGGRGGRGNASFKTAKNKAPMIAELGEKGREFWAEMELKLVADVGIIGIPNAGKSTLLASVSAAKPKIADYPFTTIVPNLGVVERDYERMVFADIPGLLEGASEGIGLGFEFLRHTKRTRVLIHVIDCASETCFEAYDAIRTELELFDEALLEKPEIVALNKVDDIEATERALQMKEKFDAEGISSHCVSAVTGEGVEELLADVQAALRALPPVEDAWAADIAETGVRAADGKSIEDFTIDDTPYAFVVAGEAIERFTQMTNWDYFESYKRFGRVLEMAGIDAALNAAGAGEGDRIIIGDFEFEWSKDRRDRTLYESFRQRVADAPGGQRGSRHWPHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV07</accession>
    <name>A4RV07_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_45061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417055.1">
        <property type="nucleotide sequence ID" value="XM_001417018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV07"/>
    <dbReference type="STRING" id="436017.A4RV07"/>
    <dbReference type="GeneID" id="5000642"/>
    <dbReference type="Gramene" id="ABO95348">
        <property type="protein sequence ID" value="ABO95348"/>
        <property type="gene ID" value="OSTLU_45061"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45061"/>
    <dbReference type="HOGENOM" id="CLU_1302503_0_0_1"/>
    <dbReference type="OMA" id="CKSFITH"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="212" mass="24406" checksum="3FAC214EECFE8C80" modified="2007-05-15" version="1" fragment="single">MQKRKEVEEAQAKAEAEARAAAEEAERLEKQKEEEEEARREAKKQKEKEKKERLRAEGKLLSNKQKAEQARLAAMRQQMLAKSGIDADKLDEVIKPKRPVYDDRKKKKEMEERRKQQQERAEAEAKAKAEEEARLAAEAEDDDAADDWEAEDWDDKEIILPGQKEEEERLAKEKAEKEAAEQKRHETEKKAAEAAAKFAAEKAIKAKIAAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVB7</accession>
    <name>A4RVB7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416814.1">
        <property type="nucleotide sequence ID" value="XM_001416777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVB7"/>
    <dbReference type="GeneID" id="5000850"/>
    <dbReference type="Gramene" id="ABO95107">
        <property type="protein sequence ID" value="ABO95107"/>
        <property type="gene ID" value="OSTLU_14846"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14846"/>
    <dbReference type="HOGENOM" id="CLU_1241581_0_0_1"/>
    <dbReference type="OMA" id="LDPKMSG"/>
    <dbReference type="OrthoDB" id="496380at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="204" mass="21794" checksum="0263857592704F55" modified="2007-05-15" version="1">MTTTTTTTTKASTTKATTKATATKTAQRPVATRAAPANATKQASAEFEAPNQYGYFPSAIEAARKKRATQTGFDKQVKMTKAEQKERFSSLCSKHPELQKCRDDYVSPLRVKPSTQSVINGSVVRSDGIILVPGNKDDLVTWALDPAMSGDTLGLLLPTLFIIIGAQLKQAAGVPEYVSGAVGVTTKLIATGLVALYWVPNFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVG4</accession>
    <name>A4RVG4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_12408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417419.1">
        <property type="nucleotide sequence ID" value="XM_001417382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVG4"/>
    <dbReference type="STRING" id="436017.A4RVG4"/>
    <dbReference type="GeneID" id="5001181"/>
    <dbReference type="Gramene" id="ABO95712">
        <property type="protein sequence ID" value="ABO95712"/>
        <property type="gene ID" value="OSTLU_12408"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12408"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025711_5_0_1"/>
    <dbReference type="OMA" id="GDSWQYL"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF45">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="210" mass="22306" checksum="6F95C0CE60DE07FF" modified="2007-05-15" version="1">MDVFRQLTEKGTWATVLQRHETNRKEIESVGGFLVKGDALNAKDVEKAMNQSDEYDAVVSTIGGTPAEPRADSEANIALIDAAAAKGVGKFVLVTSIGTGDSADAPPPNVFDALKPVLIEKAKAEEHLKVVSAKTGMAYVIVRPGGLKSEPATGTAVLTEDKSICGAIHREDVADLVIKCVLKEKANGKVLSCVDKAQLFDQPDFTPFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVJ2</accession>
    <name>A4RVJ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_37445</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417148.1">
        <property type="nucleotide sequence ID" value="XM_001417111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVJ2"/>
    <dbReference type="STRING" id="436017.A4RVJ2"/>
    <dbReference type="GeneID" id="5001150"/>
    <dbReference type="Gramene" id="ABO95441">
        <property type="protein sequence ID" value="ABO95441"/>
        <property type="gene ID" value="OSTLU_37445"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37445"/>
    <dbReference type="eggNOG" id="KOG1132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006515_4_1_1"/>
    <dbReference type="OMA" id="QFHNTLE"/>
    <dbReference type="OrthoDB" id="497061at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF47">
        <property type="entry name" value="FANCONI ANEMIA GROUP J PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="130"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="938" mass="104570" checksum="962F49208371D952" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVM5</accession>
    <name>A4RVM5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">fumarate hydratase</fullName>
            <ecNumber evidence="5">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_86934</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I fumarase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417167.1">
        <property type="nucleotide sequence ID" value="XM_001417130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVM5"/>
    <dbReference type="STRING" id="436017.A4RVM5"/>
    <dbReference type="GeneID" id="5001307"/>
    <dbReference type="Gramene" id="ABO95460">
        <property type="protein sequence ID" value="ABO95460"/>
        <property type="gene ID" value="OSTLU_86934"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86934"/>
    <dbReference type="eggNOG" id="ENOG502QT04">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026758_0_0_1"/>
    <dbReference type="OMA" id="AGVLPMC"/>
    <dbReference type="OrthoDB" id="411469at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="entry name" value="Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051208">
        <property type="entry name" value="Class-I_Fumarase/Tartrate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011167">
        <property type="entry name" value="Fe_dep_fumarate_hydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30389:SF0">
        <property type="entry name" value="FUMARATE HYDRATASE CLASS I, AEROBIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30389">
        <property type="entry name" value="FUMARATE HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001394">
        <property type="entry name" value="Fe_dep_fumar_hy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="FumA C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic" evidence="12">
        <location>
            <begin position="70"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-S hydro-lyase tartrate dehydratase beta-type catalytic" evidence="13">
        <location>
            <begin position="352"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="560" mass="61066" checksum="D2163DB22150EA9C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVM7</accession>
    <name>A4RVM7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_37384</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417169.1">
        <property type="nucleotide sequence ID" value="XM_001417132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVM7"/>
    <dbReference type="STRING" id="436017.A4RVM7"/>
    <dbReference type="GeneID" id="5001603"/>
    <dbReference type="Gramene" id="ABO95462">
        <property type="protein sequence ID" value="ABO95462"/>
        <property type="gene ID" value="OSTLU_37384"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37384"/>
    <dbReference type="eggNOG" id="KOG2227">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012774_4_2_1"/>
    <dbReference type="OMA" id="WPTDEVY"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016314">
        <property type="entry name" value="Cdc6/18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001767">
        <property type="entry name" value="Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="75"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6 C-terminal" evidence="7">
        <location>
            <begin position="348"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="442" mass="48052" checksum="0C11C294DA7536C0" modified="2007-05-15" version="1">MIAGTAAEIKLLPSTTEIDYDGAEDRPPFDPTDTSSVTTLKAAMHTSTAPDEVRCREDERAKVIDLIQGCLRDHKPGSLYLAGLPGTGKTLTLKDVQRTTERWGIVGKTRPRVAFINCMSVHNAKDIFGVVLDQLGERVASEDRAPSVGSIEYSNIPEVVALRRVVTSMNGGMCIILLDEMDQLETRDQEVLYELFALPALKGSRCVLAGVSNAINLTDRVLPRLRARGCEPALVTFSAYDAKQLKVLLKQRLAALPFKAFEDSALELCSRKVGAATGDMRKALNVCATAVDICVQEATKISEDGSEAPASAKGTVKISHMARALSKTYASPVVDSIRALPQMQQMVLCSAIKLLSSTHAMETTLGALHDRYVITCKTAGVKDLSQGEFHNMCSALSDHCLVKIGNASNDRLRKLRLLATRDDVEFSLQGVNFFRNLLGINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW46</accession>
    <name>A4RW46_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_15057</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417262.1">
        <property type="nucleotide sequence ID" value="XM_001417225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW46"/>
    <dbReference type="STRING" id="436017.A4RW46"/>
    <dbReference type="GeneID" id="5001167"/>
    <dbReference type="Gramene" id="ABO95555">
        <property type="protein sequence ID" value="ABO95555"/>
        <property type="gene ID" value="OSTLU_15057"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15057"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_20_0_1"/>
    <dbReference type="OMA" id="YSGFHGR"/>
    <dbReference type="OrthoDB" id="4255at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12937">
        <property type="entry name" value="GUCT_RH7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059027">
        <property type="entry name" value="DD_DDX21-DDX50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050547">
        <property type="entry name" value="DEAD_box_RNA_helicases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012562">
        <property type="entry name" value="GUCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963:SF8">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26142">
        <property type="entry name" value="DD_DDX21-DDX50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08152">
        <property type="entry name" value="GUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="114"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="321"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="628"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="629"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="654" mass="71653" checksum="E0EA4F0CEFC2BBA4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW82</accession>
    <name>A4RW82_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417537.1">
        <property type="nucleotide sequence ID" value="XM_001417500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW82"/>
    <dbReference type="GeneID" id="5001475"/>
    <dbReference type="Gramene" id="ABO95830">
        <property type="protein sequence ID" value="ABO95830"/>
        <property type="gene ID" value="OSTLU_15083"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15083"/>
    <dbReference type="eggNOG" id="ENOG502SFQD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_941326_0_0_1"/>
    <dbReference type="OMA" id="WTIAGEG"/>
    <dbReference type="OrthoDB" id="505263at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37201">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37201:SF1">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="32506" checksum="1FC081A6F7EAFF6D" modified="2007-05-15" version="1">MSTRCARAARGARARHARRATDASTSRERDDEDDDEDEDEDGRERAERLAAVVNCYDVAALSASATRASSYVREELAGMTTAQKMIFMDALSSTGIENAWTIAGEGYALTRAERAASAGSTKDFHAANEILGDDDANARGDGVRVFEGRVAKLPTKFLNRFAKAFYVDEDDDPMRSAASRRFLGRAPIKKGPLDALLPLYFASNDFTDDSVTIPGTGERADLSLDYRDVPVLATRRPLASRAGGVSWPAPRLALYPFDALVDYIRPLAPGVLVGRGYRFKADVPRRFLDFVLVRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWC5</accession>
    <name>A4RWC5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">CCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_37312</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CONSTANS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417557.1">
        <property type="nucleotide sequence ID" value="XM_001417520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWC5"/>
    <dbReference type="STRING" id="436017.A4RWC5"/>
    <dbReference type="GeneID" id="5001354"/>
    <dbReference type="Gramene" id="ABO95850">
        <property type="protein sequence ID" value="ABO95850"/>
        <property type="gene ID" value="OSTLU_37312"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37312"/>
    <dbReference type="eggNOG" id="KOG1601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_651150_0_0_1"/>
    <dbReference type="OMA" id="LDGAFWD"/>
    <dbReference type="OrthoDB" id="512302at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010402">
        <property type="entry name" value="CCT_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045281">
        <property type="entry name" value="CONSTANS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31319">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31319:SF77">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06203">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51017">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="9">
        <location>
            <begin position="23"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="CCT" evidence="10">
        <location>
            <begin position="310"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="257"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="360"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="45326" checksum="D0C8E831F267497B" modified="2007-05-15" version="1">MAPSDARASASDRARAEDATRDATGAACESCPEGARRAASWYCAQDEAYLCDACDARVHAANAIASKHERTALGTNGRGVGAHGAEDADSRRMSDAYGDGDDVEVTTDDVIGICDEYLSNPMMPSSSFPVETLDGAFWDENLGELDADGIDPESFLRDPLDDEDAAKDGVVNREIDGERSGSKYSDSVGMSKSEIEALRRVGEYASSSGFLGPILDDSAVRFLELNPSYGAFGSPSPESSDMGFESLAGKLSAVAVKREPESDLDNQTVASSGAGDANGHSAMADALRSIPEGPPSGSDTYAGLPQPQTRLERLKRWKEKRKNRNFNKVIRYQSRKACADNRPRVKGKFVKVSSVPDLSKIREAAGQSDDDDAREAEEERDKIAELGLDKGLRAPPSMRKMKKGLVSSASMPDFSMYNTMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWV5</accession>
    <name>A4RWV5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L27, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL27</name>
        <name evidence="5" type="ORF">OSTLU_31471</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417642.1">
        <property type="nucleotide sequence ID" value="XM_001417605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWV5"/>
    <dbReference type="STRING" id="436017.A4RWV5"/>
    <dbReference type="GeneID" id="5002152"/>
    <dbReference type="Gramene" id="ABO95935">
        <property type="protein sequence ID" value="ABO95935"/>
        <property type="gene ID" value="OSTLU_31471"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31471"/>
    <dbReference type="eggNOG" id="KOG3418">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067359_0_1_1"/>
    <dbReference type="OMA" id="NQWFFTK"/>
    <dbReference type="OrthoDB" id="1908962at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="135" mass="15258" checksum="63CB2B4B2811BB29" modified="2007-05-15" version="1">MVKFLKPGKVVVVLQGRYAGKKAVIVKNVDDGSSAHPYGHALVCGLSTIPRKVTKKMDEKKQAKRSRCKTFIKNVNYSHLMPTRYTLDVDLKNVVTSDALDNATKKVAAQKEAKKLLEERFKTGKSRWFFTRLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWY9</accession>
    <name>A4RWY9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_38395</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417905.1">
        <property type="nucleotide sequence ID" value="XM_001417868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWY9"/>
    <dbReference type="STRING" id="436017.A4RWY9"/>
    <dbReference type="GeneID" id="5002070"/>
    <dbReference type="Gramene" id="ABO96198">
        <property type="protein sequence ID" value="ABO96198"/>
        <property type="gene ID" value="OSTLU_38395"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38395"/>
    <dbReference type="eggNOG" id="ENOG502QSSP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_19_2_1"/>
    <dbReference type="OMA" id="QFFFFLY"/>
    <dbReference type="OrthoDB" id="1735926at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010102">
        <property type="term" value="P:lateral root morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01924">
        <property type="entry name" value="cyclophilin_TLP40_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.290">
        <property type="entry name" value="Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048563">
        <property type="entry name" value="CYP38_PsbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023222">
        <property type="entry name" value="PsbQ-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP38, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21329">
        <property type="entry name" value="CYP38_PsbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101112">
        <property type="entry name" value="Oxygen-evolving enhancer protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0793">Thylakoid</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="192"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="41033" checksum="FBB8F165FC60FC21" modified="2007-05-15" version="1">MAIAATACVSAPTLEAFASPVTPMEIGQVAGLEANPITNAKALLRNALPVSNKPIRAIQKKLESISDDLRVPGVKFSGVESSVNGSLKIVKEQRGKIVEALASGKKADGEQALKELESVLTDFQVIVAQKDKQEVPLQQQEALSLVGRIEEDMIDGFPFDVPAQYADRPLLKGRATVDMLVKIKDNANTDGGVLKIVLDGYNAPVSAGNFADLINLGFYDKMPIQRSDGFVVQSGKPKGGDGFKLGGVERTVPLEIMVQGDKVPEYELTLEELGRYRDQPVLPFNAFGTLAMARREAEPNSASSQFFFLLRESELTPSGTNILDGRYSIFGYVVENQELLRDLKVDDEIISMKIVDGAENLVNETKPAVDQAPIEAPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXJ3</accession>
    <name>A4RXJ3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417763.1">
        <property type="nucleotide sequence ID" value="XM_001417726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXJ3"/>
    <dbReference type="GeneID" id="5001707"/>
    <dbReference type="Gramene" id="ABO96056">
        <property type="protein sequence ID" value="ABO96056"/>
        <property type="gene ID" value="OSTLU_92754"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92754"/>
    <dbReference type="HOGENOM" id="CLU_859402_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="38267" checksum="0C14919430E59E33" modified="2007-05-15" version="1" fragment="single">VRAGVFDFFRKQIHDLSQRAGDESQRARHRARVLRHRRRIDFTRLRRQRLHGFHQRLLAQLSRGVIRVPSDDRHRSQRRRPPSQRRRFRRRHLPRRVERLHPDLSSRESSRHSPEVLLQPHFPRFAPLRLRLLQRLGRVRRRQFVPVRPQASLPAREPAGERVVSTRLAHQPSVVLDVLALSRVVLASRRRFRRARDARDDARATRLAGTTLGAYPSARARERAGALRQRRGHRARARVSALDGSSEARGAVCGAREIATRGASWRTSTRTRTPRWDWRSRTRRARRRLKRCVERATRATRDARGDATRATRRFRIRIRIRNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY25</accession>
    <name>A4RY25_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417854.1">
        <property type="nucleotide sequence ID" value="XM_001417817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY25"/>
    <dbReference type="GeneID" id="5002089"/>
    <dbReference type="Gramene" id="ABO96147">
        <property type="protein sequence ID" value="ABO96147"/>
        <property type="gene ID" value="OSTLU_31897"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31897"/>
    <dbReference type="HOGENOM" id="CLU_2214388_0_0_1"/>
    <dbReference type="OrthoDB" id="496430at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11982" checksum="BEC893EBA41174CB" modified="2007-05-15" version="1">MVKKFGPLNLVWNGVGTLQVPDAGSKPASVNLARVCLAQRAELLIENFERLYPKLKNERVEWALQPFDDQYGDAFDPFMSLPDDQVDELVPGNLQFLKKPRKVAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYB7</accession>
    <name>A4RYB7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lon N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418142.1">
        <property type="nucleotide sequence ID" value="XM_001418105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYB7"/>
    <dbReference type="GeneID" id="5002235"/>
    <dbReference type="Gramene" id="ABO96435">
        <property type="protein sequence ID" value="ABO96435"/>
        <property type="gene ID" value="OSTLU_31969"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31969"/>
    <dbReference type="eggNOG" id="ENOG502S7HJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_951454_0_0_1"/>
    <dbReference type="OMA" id="IRPALLC"/>
    <dbReference type="OrthoDB" id="264917at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="1">
        <location>
            <begin position="20"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="263" mass="27916" checksum="C8378FA11AFC6C9B" modified="2007-05-15" version="1">MDALRARVRALAKREEALETLRIVVLDASVPKQVLPLEFDGANVERTLNAGTALGRDARVGDRFGMLGQAPSNGQILPNGVEVTVTRAMVRPNGGESLIELTASRRFKIVGAPFEDEANGSAPSARVCWIPDTEGAGEQTVAGGVEEPGAVDPAECDAECAALAAELPALVDEWRALVISRKRERQPDQLKLILSQIGDIPGSNRPAELSLWVAALINPIPALGVAYEIRPAILCAPTTGHMVRIASQGIKLSINSLRDGPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYD9</accession>
    <name>A4RYD9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_15652</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad17/RAD24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418153.1">
        <property type="nucleotide sequence ID" value="XM_001418116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYD9"/>
    <dbReference type="STRING" id="436017.A4RYD9"/>
    <dbReference type="GeneID" id="5002246"/>
    <dbReference type="Gramene" id="ABO96446">
        <property type="protein sequence ID" value="ABO96446"/>
        <property type="gene ID" value="OSTLU_15652"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15652"/>
    <dbReference type="eggNOG" id="KOG1968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_323501_0_0_1"/>
    <dbReference type="OMA" id="RECATYA"/>
    <dbReference type="OrthoDB" id="9996895at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004582">
        <property type="entry name" value="Checkpoint_prot_Rad17_Rad24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172:SF1">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="292"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="765"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="848"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="894" mass="96666" checksum="EDCECD76C77E8425" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYI1</accession>
    <name>A4RYI1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Plastid ribosomal protein L13 large ribosomal subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRPL13</name>
        <name evidence="6" type="ORF">OSTLU_15678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418394.1">
        <property type="nucleotide sequence ID" value="XM_001418357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYI1"/>
    <dbReference type="STRING" id="436017.A4RYI1"/>
    <dbReference type="GeneID" id="5002463"/>
    <dbReference type="Gramene" id="ABO96687">
        <property type="protein sequence ID" value="ABO96687"/>
        <property type="gene ID" value="OSTLU_15678"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15678"/>
    <dbReference type="eggNOG" id="KOG3203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082184_0_1_1"/>
    <dbReference type="OMA" id="KPWVVID"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23356" checksum="24A959FD77A2D055" modified="2007-05-15" version="1">MASLAPVRAPTAAPKRQQAAKPSPGRRCGVQTRGHSLGSLPPELGVTAEKLGRDVFNTTYYPKGEDADASRKPWVVIDAAGLRLGRLSTVAATYLRGGNSGCYTPAFNMGVNVVVINADKIVVTGNKANQKLYYTLGVRGKPGSMKEETYASLHARQPARVIEKAIKGMLPKNRMGRETFTHLKVYAGADHPHAAQNPTDVTADVKAATHKAHMLEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYL5</accession>
    <name>A4RYL5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_4622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the formin-like family. Class-II subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418413.1">
        <property type="nucleotide sequence ID" value="XM_001418376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYL5"/>
    <dbReference type="STRING" id="436017.A4RYL5"/>
    <dbReference type="GeneID" id="5002573"/>
    <dbReference type="Gramene" id="ABO96706">
        <property type="protein sequence ID" value="ABO96706"/>
        <property type="gene ID" value="OSTLU_4622"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4622"/>
    <dbReference type="eggNOG" id="KOG1922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1079932_0_0_1"/>
    <dbReference type="OMA" id="EDICHLE"/>
    <dbReference type="OrthoDB" id="1668162at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051144">
        <property type="entry name" value="Formin_homology_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733:SF8">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FH2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="222" mass="24678" checksum="FBCABE91B549864E" modified="2007-05-15" version="1" fragment="single">IDQKRSLNISIQLAGLRMPFDRIKDALLAMDDEVLQSEQLEVISSTVPTSKEITLIMDYKGAKEELATVEQYFMHVMQIPRLEGRVNSLLYKSLASDALLKVTSEYRLLSEASDCLRESTLFVKVLRGVLVVGNHLNTGSYRGSASGFRLDMLLRLKDFKAVDRKTSLLHFVYKELVKTEPGIGNLSTDLAVVKKAAALSIETTSANLGKLQDGLTKVKDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYZ1</accession>
    <name>A4RYZ1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA mismatch repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_40782</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418476.1">
        <property type="nucleotide sequence ID" value="XM_001418439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYZ1"/>
    <dbReference type="STRING" id="436017.A4RYZ1"/>
    <dbReference type="GeneID" id="5002498"/>
    <dbReference type="Gramene" id="ABO96769">
        <property type="protein sequence ID" value="ABO96769"/>
        <property type="gene ID" value="OSTLU_40782"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40782"/>
    <dbReference type="eggNOG" id="KOG0217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_1_3_1"/>
    <dbReference type="OMA" id="YWTPNIK"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006290">
        <property type="term" value="P:pyrimidine dimer repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000005">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF150">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="9">
        <location>
            <begin position="487"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="10">
        <location>
            <begin position="864"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="670"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR037677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1113" mass="119716" checksum="EB4E92970064B997" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYZ6</accession>
    <name>A4RYZ6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418481.1">
        <property type="nucleotide sequence ID" value="XM_001418444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYZ6"/>
    <dbReference type="GeneID" id="5002348"/>
    <dbReference type="Gramene" id="ABO96774">
        <property type="protein sequence ID" value="ABO96774"/>
        <property type="gene ID" value="OSTLU_32198"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32198"/>
    <dbReference type="HOGENOM" id="CLU_530411_0_0_1"/>
    <dbReference type="OMA" id="KLETPVY"/>
    <dbReference type="OrthoDB" id="10473554at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="515" mass="57163" checksum="017D6A907445C3AD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ00</accession>
    <name>A4RZ00_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_45844</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418248.1">
        <property type="nucleotide sequence ID" value="XM_001418211.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RZ00"/>
    <dbReference type="GeneID" id="5002541"/>
    <dbReference type="Gramene" id="ABO96541">
        <property type="protein sequence ID" value="ABO96541"/>
        <property type="gene ID" value="OSTLU_45844"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45844"/>
    <dbReference type="eggNOG" id="KOG1858">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001202_0_0_1"/>
    <dbReference type="OrthoDB" id="26401at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048971">
        <property type="entry name" value="Apc1_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041221">
        <property type="entry name" value="APC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046794">
        <property type="entry name" value="Apc1_MidN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21282">
        <property type="entry name" value="APC1_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18122">
        <property type="entry name" value="APC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20518">
        <property type="entry name" value="Apc1_MidN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 middle" evidence="8">
        <location>
            <begin position="472"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 beta-sandwich" evidence="9">
        <location>
            <begin position="1227"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 C-terminal" evidence="7">
        <location>
            <begin position="1369"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="897"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1578" mass="168857" checksum="8C0E3512E52A82FC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ18</accession>
    <name>A4RZ18_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Pterin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_2171</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418496.1">
        <property type="nucleotide sequence ID" value="XM_001418459.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ18"/>
    <dbReference type="STRING" id="436017.A4RZ18"/>
    <dbReference type="GeneID" id="5002273"/>
    <dbReference type="Gramene" id="ABO96789">
        <property type="protein sequence ID" value="ABO96789"/>
        <property type="gene ID" value="OSTLU_2171"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2171"/>
    <dbReference type="eggNOG" id="KOG2544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008023_2_1_1"/>
    <dbReference type="OMA" id="NIPHKLM"/>
    <dbReference type="OrthoDB" id="615426at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000006">
        <property type="entry name" value="Dihydropteroate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="15">
        <location>
            <begin position="188"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO96789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="468" mass="49878" checksum="D2625FD4E0BDAA80" modified="2007-05-15" version="1" fragment="single">VLALGSNQGDRVGLFRDAFAKLRRDLGFELHAHSSLYETAPAYVEDQGKFLNAACVGSFPDDVARDPLALLDGLKAIEAALGRDFGTRRYGPRPMDLDVIFHGQGSHSCDRLTVPHARYAERPFVLAPLADLTGAATAATTSDATTEGLLEARRIWDGTDGEVTAMESGDIARVIPMRDRLWSWGRETMVMGILNVTPDSFSDGGAYDGGVDVAVRHAREMVAAGATIIDVGGQSTRPGATRVSGEVESSRVIPVIRALAQAFSEREDVYISVDTFYGAVASAAADAGADIINDVSGGAWDPAMLPTVARLEKPLPYVVMHVRGDPNSMQSAKNTTYDGHICDEVGDGLLATARRCVEYGIEPWRLWIDPGIGFAKTGRANIELLRDLPRVRSRLAPLGGALMNAPMLVGASRKRFLGEISGRSEASERDAASVAALVAAVRGGADVVRVHNVALSADAARVADALWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZF9</accession>
    <name>A4RZF9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418325.1">
        <property type="nucleotide sequence ID" value="XM_001418288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZF9"/>
    <dbReference type="GeneID" id="5002377"/>
    <dbReference type="Gramene" id="ABO96618">
        <property type="protein sequence ID" value="ABO96618"/>
        <property type="gene ID" value="OSTLU_92947"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92947"/>
    <dbReference type="HOGENOM" id="CLU_904285_0_0_1"/>
    <dbReference type="OrthoDB" id="10631031at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="34452" checksum="526026A4DDDDA6CD" modified="2007-05-15" version="1">MARKKTKKRPVIARDDVESRATLKSDDETEDYDDADSSPARVPNGVDASRVAFGARASPSRVRGEDEGPVKLCVTVRPQVVVDDDEASMRIDILEEVVEDLKLELDGYRAAARELAIEIEAKDRALEASARDTRHEKTEGRALAVREATARLTDRLEKAEKAVERERGDGDRGRKALETLKKMEAELERRMCDQDEAFELKWAQRVAEANADRDAFRGKLAKLEGEMETVKISEERARSELVSAKRQIDELQLRLARALSAPAPRGNERTDDPRDVVDDDASKPRRGFFSFITGVPEAPKSDRPVVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZH1</accession>
    <name>A4RZH1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_40909</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="9"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418570.1">
        <property type="nucleotide sequence ID" value="XM_001418533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZH1"/>
    <dbReference type="STRING" id="436017.A4RZH1"/>
    <dbReference type="GeneID" id="5002607"/>
    <dbReference type="Gramene" id="ABO96863">
        <property type="protein sequence ID" value="ABO96863"/>
        <property type="gene ID" value="OSTLU_40909"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40909"/>
    <dbReference type="eggNOG" id="KOG1389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_1_1_1"/>
    <dbReference type="OMA" id="NASPMND"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000010">
        <property type="entry name" value="Acetyl-CoA acetyltransferase (Thiolase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="12">
        <location>
            <begin position="29"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="13">
        <location>
            <begin position="295"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="10">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="42960" checksum="C6AA7CEB639C2260" modified="2007-05-15" version="1">MNECARRPRDARLTTRIDAQGFAKSPDDVVIVSACRTPITRAKRGGLAATPADDLIAAVLQASVARGKIDVNDVGDIVVGSVLGASSQRANECRIGMFLAGFPKEVPVRTTNRQCSSGLQACADIAAGIKAGYYDMGIGAGVETMTANPMKWEGGINPRIASSSDAQNCLIPMGITSENVAEKWGITREAQDTMAARSHARAANARASGRFKAEIVPIHTKTAPDPKTGAGGGANVIVSEDDGIREGTTVQSLAKLPAVFKKGGSTTPGNASQVSDGAAAVVLARRSYAEARGLPILATWRSWAAVGCDPALMGIGPAIAIPATLSAANMTVDDVDLYEINEAFASQATYCVEKLGLDSEKVNVNGGAIALGHPLGATGARCLATLIHEMHRRGAKTGVVSMCIGSGMGMASAVSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZS2</accession>
    <name>A4RZS2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32486</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418847.1">
        <property type="nucleotide sequence ID" value="XM_001418810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZS2"/>
    <dbReference type="STRING" id="436017.A4RZS2"/>
    <dbReference type="GeneID" id="5003049"/>
    <dbReference type="Gramene" id="ABO97140">
        <property type="protein sequence ID" value="ABO97140"/>
        <property type="gene ID" value="OSTLU_32486"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32486"/>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_18_15_1"/>
    <dbReference type="OMA" id="INCERNS"/>
    <dbReference type="OrthoDB" id="566279at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="293" mass="32584" checksum="C9BC2525EECDC65E" modified="2007-05-15" version="1">MSVDEVFARVANAWNEVTSSVDAAWDAAWRSRNRANAEESRKKTALATGIVTERDARHARVPPYVFERDVGARVRVLDLASNAIVDVDDAIGSLRNAQKVNLSFNAVRALPRAFSTLVNLKTLDLRGNKLTALPEDIDSLLALEDLDVRENALRALPRTLGKCKRLRRLDASANALTTFDDAIAGLGNCADLEVIRFARNREMRGALPVAWAHAVKLKEIDVDDTKCDGVPGEILLACDRLTTLSLRRTLVDVGTLKRTDGFESYESRRQGKHNKQLDSRVLLDDSRLDERLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZZ8</accession>
    <name>A4RZZ8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418886.1">
        <property type="nucleotide sequence ID" value="XM_001418849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZZ8"/>
    <dbReference type="GeneID" id="5002820"/>
    <dbReference type="Gramene" id="ABO97179">
        <property type="protein sequence ID" value="ABO97179"/>
        <property type="gene ID" value="OSTLU_16081"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16081"/>
    <dbReference type="eggNOG" id="ENOG502S3XU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013827_0_0_1"/>
    <dbReference type="OMA" id="QVNERSH"/>
    <dbReference type="OrthoDB" id="78067at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37028:SF4">
        <property type="entry name" value="ALMS MOTIF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37028">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="547" mass="63201" checksum="990A7CD7162A1147" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZZ9</accession>
    <name>A4RZZ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_32569</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast stroma</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Plastid</location>
            <location evidence="12">Chloroplast thylakoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418657.1">
        <property type="nucleotide sequence ID" value="XM_001418620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZZ9"/>
    <dbReference type="STRING" id="436017.A4RZZ9"/>
    <dbReference type="GeneID" id="5002868"/>
    <dbReference type="Gramene" id="ABO96950">
        <property type="protein sequence ID" value="ABO96950"/>
        <property type="gene ID" value="OSTLU_32569"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32569"/>
    <dbReference type="eggNOG" id="ENOG502QRFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024865_3_1_1"/>
    <dbReference type="OMA" id="FKFEGRQ"/>
    <dbReference type="OrthoDB" id="70257at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009534">
        <property type="term" value="C:chloroplast thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070938">
        <property type="term" value="C:contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010020">
        <property type="term" value="P:chloroplast fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000001">
        <property type="entry name" value="Cell division protein FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000007">
        <property type="entry name" value="Cell division protein ftsZ, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="CELL DIVISION PROTEIN FTSZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314:SF3">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN FSZA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="14">
        <location>
            <begin position="17"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="15">
        <location>
            <begin position="213"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="329"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO96950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="40708" checksum="64653F1B14EA3A8B" modified="2007-05-15" version="1">MTRRSGTTTRAATNAATIKVVGVGGGGSNAVNRMVDADINGVEFWIVNTDAQALETAVADPRNHLQIGAELTRGLGAGGNPEIGQKAAEESRAAIEQALSGSDMVFVTAGMGGGTGSGAAPVVAQVAKSAGILTVGIVTMPFKFEGRQRYNQAMEAVERLRQNVDTLIVIPNDRLLAAVDASLPVQDAFLLADDILRQGVRGITDIITLPGLINVDFADVRAVMADAGSSLMGIGRASGKNRAREAAEAAISSPLLDLGIDRATGIVWNITGGSDLTLHEVNEAAEVIYDLVDPSALIIFGAVVKDGNRATDGEVSITLIATGFSPSAGISQTAAPASRSNGKKAPAAIDGRTPIMGWNTKTEIPSNGKSERDEEQPASRGGIPSFLRRRMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S047</accession>
    <name>A4S047_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_87761</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418911.1">
        <property type="nucleotide sequence ID" value="XM_001418874.1"/>
    </dbReference>
    <dbReference type="GeneID" id="5002998"/>
    <dbReference type="Gramene" id="ABO97204">
        <property type="protein sequence ID" value="ABO97204"/>
        <property type="gene ID" value="OSTLU_87761"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87761"/>
    <dbReference type="HOGENOM" id="CLU_237568_0_0_1"/>
    <dbReference type="OMA" id="ICKNECH"/>
    <dbReference type="OrthoDB" id="10621424at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870:SF9">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="228"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="389"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="617"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="735"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="859"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="941"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1163"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1280"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1408"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1823" mass="196463" checksum="E5BA51B1E845C41C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0E2</accession>
    <name>A4S0E2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">U6 snRNA-associated Sm-like protein LSm5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSM5</name>
        <name evidence="12" type="ORF">OSTLU_32713</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418730.1">
        <property type="nucleotide sequence ID" value="XM_001418693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0E2"/>
    <dbReference type="STRING" id="436017.A4S0E2"/>
    <dbReference type="GeneID" id="5002898"/>
    <dbReference type="Gramene" id="ABO97023">
        <property type="protein sequence ID" value="ABO97023"/>
        <property type="gene ID" value="OSTLU_32713"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32713"/>
    <dbReference type="eggNOG" id="KOG1775">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_6_1_1"/>
    <dbReference type="OMA" id="YETTPQG"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120115">
        <property type="term" value="C:Lsm2-8 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009414">
        <property type="term" value="P:response to water deprivation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000003">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="16"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="93" mass="10055" checksum="ABBDE88BF037ED3E" modified="2007-05-15" version="1">MALPAKAANANPSLVLPSELVERCVGSPLWVLMKSERELVGTLRGFDVYVNMVLEDVTEYETTAEGRRVTGRLDQILLNGNNIAMLVPGGGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0J2</accession>
    <name>A4S0J2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">BRD3501</name>
        <name evidence="11" type="ORF">OSTLU_93058</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418985.1">
        <property type="nucleotide sequence ID" value="XM_001418948.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S0J2"/>
    <dbReference type="GeneID" id="5002825"/>
    <dbReference type="Gramene" id="ABO97278">
        <property type="protein sequence ID" value="ABO97278"/>
        <property type="gene ID" value="OSTLU_93058"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93058"/>
    <dbReference type="eggNOG" id="KOG0386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1827">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_259236_0_0_1"/>
    <dbReference type="OMA" id="RRKCFEI"/>
    <dbReference type="OrthoDB" id="200660at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF22">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="893"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="1197"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="34"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="615"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="823"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="989"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1155"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1306"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1306"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1316"/>
            <end position="1329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1329" mass="151248" checksum="2790F61A247A0333" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0L4</accession>
    <name>A4S0L4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32787</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418999.1">
        <property type="nucleotide sequence ID" value="XM_001418962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0L4"/>
    <dbReference type="GeneID" id="5002785"/>
    <dbReference type="Gramene" id="ABO97292">
        <property type="protein sequence ID" value="ABO97292"/>
        <property type="gene ID" value="OSTLU_32787"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32787"/>
    <dbReference type="HOGENOM" id="CLU_426645_0_0_1"/>
    <dbReference type="OMA" id="HCIANAW"/>
    <dbReference type="OrthoDB" id="543760at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF15">
        <property type="entry name" value="INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="741" mass="84199" checksum="B78B5E42087CFA51" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0V4</accession>
    <name>A4S0V4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">adenylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_87896</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419254.1">
        <property type="nucleotide sequence ID" value="XM_001419217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0V4"/>
    <dbReference type="STRING" id="436017.A4S0V4"/>
    <dbReference type="GeneID" id="5003440"/>
    <dbReference type="Gramene" id="ABO97547">
        <property type="protein sequence ID" value="ABO97547"/>
        <property type="gene ID" value="OSTLU_87896"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87896"/>
    <dbReference type="eggNOG" id="KOG3078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032354_6_1_1"/>
    <dbReference type="OMA" id="YHEMLDG"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="229" mass="24703" checksum="E67FC4B301387CB9" modified="2007-05-15" version="1" fragment="single">VAIAAAALAIKASKSSTIGGASKQKRIVIAGAPASGKGTQCEMIVKKFGLTHISAGDLLRAAVAAGTDAGKKAKEYMDRGDLVPNEVVVTMVKDRLAQPDCAKGWLLDGYPRSEEQAEALIESGIDPDLFLLLDVPDEILIDRVVGRRLDPVDGTIYHMTFFPPPTPEIAARLTQRSDDTEEKAANRLAVHHKNVDAVVGKYESIMKNVDGNRAKQDVFKDIERLIKAM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-01-11" modified="2025-02-05" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1G4</accession>
    <name>FEN1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flap endonuclease 1</fullName>
            <shortName evidence="1">FEN-1</shortName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Flap structure-specific endonuclease 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FEN1</name>
        <name type="ORF">OSTLU_42373</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
        <text evidence="1">Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419144.1">
        <property type="nucleotide sequence ID" value="XM_001419107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1G4"/>
    <dbReference type="SMR" id="A4S1G4"/>
    <dbReference type="STRING" id="436017.A4S1G4"/>
    <dbReference type="EnsemblPlants" id="ABO97437">
        <property type="protein sequence ID" value="ABO97437"/>
        <property type="gene ID" value="OSTLU_42373"/>
    </dbReference>
    <dbReference type="GeneID" id="5003467"/>
    <dbReference type="Gramene" id="ABO97437">
        <property type="protein sequence ID" value="ABO97437"/>
        <property type="gene ID" value="OSTLU_42373"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42373"/>
    <dbReference type="eggNOG" id="KOG2519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032444_2_0_1"/>
    <dbReference type="OMA" id="MGIPWVQ"/>
    <dbReference type="OrthoDB" id="1937206at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09867">
        <property type="entry name" value="PIN_FEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000009">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000016">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00614">
        <property type="entry name" value="Fen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023426">
        <property type="entry name" value="Flap_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0269">Exonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000403524" description="Flap endonuclease 1">
        <location>
            <begin position="1"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-domain">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="I-domain">
        <location>
            <begin position="123"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with PCNA" evidence="1">
        <location>
            <begin position="338"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
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    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
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        <ligand>
            <name>Mg(2+)</name>
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            <label>1</label>
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        <location>
            <position position="161"/>
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            <name>Mg(2+)</name>
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            <label>1</label>
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        <location>
            <position position="180"/>
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        <ligand>
            <name>Mg(2+)</name>
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            <label>2</label>
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        <location>
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        <ligand>
            <name>Mg(2+)</name>
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        <location>
            <position position="232"/>
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        <ligand>
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        <location>
            <position position="234"/>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_03140"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="389" mass="43044" checksum="2573D33D5FAE5A4D" modified="2007-05-15" version="1">MGIKGLTALMRDNAPGAIKEQKFESYLDRRVAIDASMHIYQFMMVVGRQGEQQLTNEAGEVTSHLQGMLNRTCRMLEAGIKPIYVFDGKPPVMKGGELAKRKDKREEAEAALKAAREAGNQEEVEKLSKRTVRVSKQHSQEVMKLASLLGVPVFEAPCEAEASCAAMCKAGLVWAVATEDMDTLTFAAPRLARNLMAPKSQDKPVLEFDYDKVLAGLGLTPEQFIDMCILCGCDYCDTIRGIGPKTALKLIKEHGSIEKILEEIDTEKYPPPQDWDFAGARELFKNPEVMDTTGIALSWKAPNEEGLIDFLVKEKQFNEERVRAVCAKVKKARQGKASQNRLESFFGPPTIISSTIGKRKVEEKKGKNGKAGLANKKSKGVSGFRRSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1T0</accession>
    <name>A4S1T0_OSTLU</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_93163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO97713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001419383.1"/>
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        <property type="protein sequence ID" value="ABO97713"/>
        <property type="gene ID" value="OSTLU_93163"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93163"/>
    <dbReference type="eggNOG" id="ENOG502QUC4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_493139_0_0_1"/>
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    <dbReference type="OrthoDB" id="745018at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:chromatin binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007389">
        <property type="term" value="P:pattern specification process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055315">
        <property type="entry name" value="Cramped-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21677">
        <property type="entry name" value="CRAMPED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21677:SF1">
        <property type="entry name" value="PROTEIN CRAMPED-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
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            <begin position="438"/>
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        <location>
            <begin position="540"/>
            <end position="561"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="47"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="561" mass="61321" checksum="5E47FB55E301FB7B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1V8</accession>
    <name>A4S1V8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">A to I editase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419433.1">
        <property type="nucleotide sequence ID" value="XM_001419396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1V8"/>
    <dbReference type="GeneID" id="5003132"/>
    <dbReference type="Gramene" id="ABO97726">
        <property type="protein sequence ID" value="ABO97726"/>
        <property type="gene ID" value="OSTLU_33237"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33237"/>
    <dbReference type="eggNOG" id="KOG2777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_633647_0_0_1"/>
    <dbReference type="OMA" id="NACVRRW"/>
    <dbReference type="OrthoDB" id="10268011at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003726">
        <property type="term" value="F:double-stranded RNA adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008251">
        <property type="term" value="F:tRNA-specific adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006382">
        <property type="term" value="P:adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910:SF62">
        <property type="entry name" value="AT07585P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910">
        <property type="entry name" value="EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A to I editase" evidence="2">
        <location>
            <begin position="70"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="439" mass="47920" checksum="23332462E5D9A4D9" modified="2007-05-15" version="1">MAPPPKRTRLAEKPRAGTCALADRIARCAIDAYAAQRASCGVDVAEFPVRTVLAAFILRDDARDSLRVLSLGVGTKTLGRYACTTGRALVDCHAEVLARRGLKKFLLRDARAALRGGDANDGDVVVRTREGDVKVKDGLSLHLYVSSAPCGNACVRRWAKGRSTKRRDELGTANAPSEPHETLSRSATDAGQVALCVKVIKASKDEDVPEVLRDMVTRGELAAGTAPARGDGDEALTCSDKLCVWNVVGYQGALLRRFMREPLYVETITIGRKFSEPHLCRAMCCRVDGFRSSCGGFATTHPALMETAVVFDDVPMDVEEGAVFENPFAMIWCDGDDAAEALNGKTGTFLHEDASAPSTSKAALYELYLSLLGEDVGDSPTFTLEAYARAKREADEKYDAAKTELFEHPKMFEPRRGFDGWHEKKSKRWSGYKRTASRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Z5</accession>
    <name>A4S1Z5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4 9">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_42728</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4 9"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419235.1">
        <property type="nucleotide sequence ID" value="XM_001419198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Z5"/>
    <dbReference type="STRING" id="436017.A4S1Z5"/>
    <dbReference type="GeneID" id="5003150"/>
    <dbReference type="Gramene" id="ABO97528">
        <property type="protein sequence ID" value="ABO97528"/>
        <property type="gene ID" value="OSTLU_42728"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42728"/>
    <dbReference type="eggNOG" id="KOG0544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098197_2_0_1"/>
    <dbReference type="OMA" id="HSHEGGC"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47861">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47861:SF3">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="11">
        <location>
            <begin position="45"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="180" mass="19242" checksum="096AEADCC3C180E0" modified="2007-05-15" version="1" fragment="single">MHAVRAYARPASASRRPTLGRQSIAAPRRGFTVSARASDKTVEKGDAVAIHYVGTLEDGTTFDSSRERNEPIKFTVGSGMMIPGFDKGVLGLAVGQSKTIKCAPADAYGEVRPENILRVPKKDVVDAVGEDFVKVGEKLMVGQGMPAEIIEVTDSEVALDANHPLAGKTLNFDIELMSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S279</accession>
    <name>A4S279_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_33356</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orai family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419702.1">
        <property type="nucleotide sequence ID" value="XM_001419665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S279"/>
    <dbReference type="STRING" id="436017.A4S279"/>
    <dbReference type="GeneID" id="5003640"/>
    <dbReference type="Gramene" id="ABO97995">
        <property type="protein sequence ID" value="ABO97995"/>
        <property type="gene ID" value="OSTLU_33356"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33356"/>
    <dbReference type="eggNOG" id="ENOG502S00K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620224_0_0_1"/>
    <dbReference type="OMA" id="VEERDWW"/>
    <dbReference type="OrthoDB" id="61124at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.140">
        <property type="entry name" value="Calcium release-activated calcium channel protein Orai"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012446">
        <property type="entry name" value="CRAC_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038350">
        <property type="entry name" value="Orai_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31501">
        <property type="entry name" value="CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31501:SF7">
        <property type="entry name" value="CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07856">
        <property type="entry name" value="Orai-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="335"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="442" mass="50460" checksum="8AF0C9139FF8B76C" modified="2007-05-15" version="1">MPSFAGVGAGDVGDAATAFLTALDTSLARAWREEDRQWRKEERQWRREDLEFRVEERDWWELEHVHRDEQRKWRRQDVEQRVLENARWVWNRYAEKNRRDVEEKGEQLRTTSNLSALISGFAVVALVELQFSDPTVKAFQSEALIAAYAGATAVTVALMLNAMVLCSFMLSNILRNGKSYVSEDEEAEFLYACRKFALSYAPGDTPPQPQRSFERYWETRCEADWRKAFRMFTYGVPMFLTTLTLSAWLKFWYSTVTCSIVTGVAAVAIGLWWRTQSAWGWHLMKRSEQQFSKSRYFPPEGLPFDWHARPRKKPTDSDLGSMRNNSGASDEDFFAASPSVSRSESLSRAEPPSDASAARVDASTIAHHNGTTTKQNASGAKRDPYAGLKIDTRLRAVAVEAVSDREREFLRDSSPRAIETTKREYEKVGLKSKLVDQRAGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2B2</accession>
    <name>A4S2B2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419721.1">
        <property type="nucleotide sequence ID" value="XM_001419684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2B2"/>
    <dbReference type="GeneID" id="5003535"/>
    <dbReference type="Gramene" id="ABO98014">
        <property type="protein sequence ID" value="ABO98014"/>
        <property type="gene ID" value="OSTLU_33388"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33388"/>
    <dbReference type="HOGENOM" id="CLU_3017639_0_0_1"/>
    <dbReference type="OMA" id="HKATKGH"/>
    <dbReference type="OrthoDB" id="5107at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020526">
        <property type="entry name" value="Ribosomal_cL38"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17257">
        <property type="entry name" value="DUF5323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="56" mass="6270" checksum="EB2981DC10505F11" modified="2007-05-15" version="1">MTFTVKAARHVRKKATKGHTDTRPKKHRPSDRNRKAVEYPTVDPATAPAVMTVVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2D9</accession>
    <name>A4S2D9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PUA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_12867</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419513.1">
        <property type="nucleotide sequence ID" value="XM_001419476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2D9"/>
    <dbReference type="STRING" id="436017.A4S2D9"/>
    <dbReference type="GeneID" id="5003736"/>
    <dbReference type="Gramene" id="ABO97806">
        <property type="protein sequence ID" value="ABO97806"/>
        <property type="gene ID" value="OSTLU_12867"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12867"/>
    <dbReference type="eggNOG" id="KOG1154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025400_2_0_1"/>
    <dbReference type="OMA" id="SVTELMF"/>
    <dbReference type="OrthoDB" id="409889at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009084">
        <property type="term" value="P:glutamine family amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000018">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF3">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="8">
        <location>
            <begin position="288"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="413" mass="43690" checksum="BA29B8FFA841687C" modified="2007-05-15" version="1">MSRDDGAKDKRPIVVIKVGTSSLLKTNDGCVHLSQLCALCETVANLKRHGYHVVLVSSGAVGAGMVKMGIKPSATKPSLARKQALAAIGQPYLMRYYTDVFSSLGASCAQVLLTLENLSNRTQYQKAKQTFEQLFELGAIPVVNENDTVAVEELRFGDNDTLSAQVAALVEAQYLFLLTDVDGLYTSNPASDPAAKKIETVEDINALDVDVNSGAGSNVGTGGMVTKLTAARIASAAGCQTVICLASVQGTAIMDVLAGKSGIGTRFLAAKKSARGKKRWLLSVPIKGEVRVDEDGAKAVLNGMALMVSKCVAVEGTFGLQESVRILDENGAELGRGLSNYIIGAMRDFLQRGPATSDDEWEDDLDGPPELIHSNNVCITNAETLAKSFVLRNIGTYGSMMMDGGASSGDDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2P9</accession>
    <name>A4S2P9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proliferating cell nuclear antigen PCNA C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_33526</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419570.1">
        <property type="nucleotide sequence ID" value="XM_001419533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2P9"/>
    <dbReference type="STRING" id="436017.A4S2P9"/>
    <dbReference type="GeneID" id="5003569"/>
    <dbReference type="Gramene" id="ABO97863">
        <property type="protein sequence ID" value="ABO97863"/>
        <property type="gene ID" value="OSTLU_33526"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33526"/>
    <dbReference type="HOGENOM" id="CLU_1322818_0_0_1"/>
    <dbReference type="OrthoDB" id="337581at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003021">
        <property type="entry name" value="Rad1_Rec1_Rad17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="22153" checksum="CE5E5265CB8F806C" modified="2007-05-15" version="1">MLTLELESAKGQGGERELRQCVYAEIAPEMVPEDEERGEEVSFRDEANAFMLPTATLKEIVDDLEWPNGDVLLECDVDMLKFSAHGAEIGDLAVDVDVGATGRLTEFSCAQPSASRYKYRFLKSATAVGGSFLGGGGAGAGGGGGDDTVTMTRVSISNVGFLKIVHLLHLSRGQVSFGAEGGLNAFMVPVTYILHPIEADADEYADEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S312</accession>
    <name>A4S312_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_50496</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419633.1">
        <property type="nucleotide sequence ID" value="XM_001419596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S312"/>
    <dbReference type="STRING" id="436017.A4S312"/>
    <dbReference type="GeneID" id="5003900"/>
    <dbReference type="Gramene" id="ABO97926">
        <property type="protein sequence ID" value="ABO97926"/>
        <property type="gene ID" value="OSTLU_50496"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50496"/>
    <dbReference type="eggNOG" id="KOG0474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003181_4_1_1"/>
    <dbReference type="OMA" id="METTGSM"/>
    <dbReference type="OrthoDB" id="428525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF136">
        <property type="entry name" value="H(+)_CL(-) EXCHANGE TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="10 12" id="KW-0868">Chloride</keyword>
    <keyword evidence="7 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="589"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="713"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="826"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="826"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="869" mass="95063" checksum="17268AA31E2F72E4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S399</accession>
    <name>A4S399_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER"/>
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        <property type="entry name" value="TELO2-INTERACTING PROTEIN 1 HOMOLOG"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="24"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="TTI1 C-terminal TPR" evidence="2">
        <location>
            <begin position="836"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1073" mass="116260" checksum="4815601DC6742F19" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3D3</accession>
    <name>A4S3D3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_16978</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">CCE9901</strain>
        </source>
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    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16978"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120:SF11">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
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            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="EngC GTPase" evidence="4">
        <location>
            <begin position="62"/>
            <end position="213"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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            <end position="295"/>
        </location>
    </feature>
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            <end position="315"/>
        </location>
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        <location>
            <begin position="316"/>
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        </location>
    </feature>
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        <location>
            <begin position="326"/>
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        </location>
    </feature>
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            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO98367.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39321" checksum="5A314B09D178D146" modified="2007-05-15" version="1">MLAEEDRTTELLCVARALLKKIKKRVLVGDEVVLSGVDWVQSRGMIDDVVGRRSELVEPPIANVDQALLVFALEQPPLEVKQLTRFLVSMEATKVPFTLVLNKCELLSEVEVADWRARLESWGYDAKVISVATGQGVEELEEALRGKTTVLAGPSGVGKSSLINRFRFGSALADLQSVKGVGTRSGRGKHTTRHVSLLRLDVGGFLADTPGFGYPSLEGFDTDKLAMCFPEIRDALASSDARCQFSDCTHRHEPGCVVVDECWEERRYDLYYDLFEEVKQIADTERMASGRESRTKTKSAAGKDATRTEAKLETKSHRRVSRRRSRMETEDLRARALDDDDGDDNYDDEDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3R9</accession>
    <name>A4S3R9_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17077</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420143.1">
        <property type="nucleotide sequence ID" value="XM_001420106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3R9"/>
    <dbReference type="GeneID" id="5004152"/>
    <dbReference type="Gramene" id="ABO98436">
        <property type="protein sequence ID" value="ABO98436"/>
        <property type="gene ID" value="OSTLU_17077"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17077"/>
    <dbReference type="eggNOG" id="ENOG502SZSH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1535043_0_0_1"/>
    <dbReference type="OMA" id="ATNACEL"/>
    <dbReference type="OrthoDB" id="10611494at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="175" mass="18474" checksum="88F37E59A5304B68" modified="2007-05-15" version="1">MDPATGLPYGWNERTNAVSDPGRVATASFSARGAYGASDEGDASYKTSEEVEAYWMSKIDAERRAQAPAPPGKKSHDEAKSTQKRLPIDWDERAKRRAADAERYGASANASGGSDATASASAATSPELALVRVATNACELLAAVLDQRLVSLPEEDRAAFAAAVSRSLALVVKCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3T8</accession>
    <name>A4S3T8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_4102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419977.1">
        <property type="nucleotide sequence ID" value="XM_001419940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3T8"/>
    <dbReference type="STRING" id="436017.A4S3T8"/>
    <dbReference type="GeneID" id="5004161"/>
    <dbReference type="Gramene" id="ABO98270">
        <property type="protein sequence ID" value="ABO98270"/>
        <property type="gene ID" value="OSTLU_4102"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4102"/>
    <dbReference type="eggNOG" id="KOG2649">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1154234_0_0_1"/>
    <dbReference type="OrthoDB" id="10249045at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050753">
        <property type="entry name" value="Peptidase_M14_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11532:SF57">
        <property type="entry name" value="CARBOXYPEPTIDASE D, B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11532">
        <property type="entry name" value="PROTEASE M14 CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M14" evidence="3">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="241" mass="26527" checksum="1584CC67BCFC33B8" modified="2007-05-15" version="1" fragment="single">FGFIGNMHGDEPVGREIAMEVGRWVCERATTTRETTSEAETRERALAKRLVNEATLFVVPTVNPDGFAAKTRGNARGVDLNRNFPYTRFSLPKSLSGRASATALIMRWSEKWAMNGALNYHEGALVANYPWDGNDDGSTSYSAAPDDATFRYLASSYAQAHPTMSKSAEFEGGITNGAAWYPLWGGMQDWHYVQTGTYSLTVEVDDEKWPSEDKLGAIVDEHVNASIDCVASNCRTGEHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3X4</accession>
    <name>A4S3X4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_9623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419996.1">
        <property type="nucleotide sequence ID" value="XM_001419959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3X4"/>
    <dbReference type="STRING" id="436017.A4S3X4"/>
    <dbReference type="GeneID" id="5004035"/>
    <dbReference type="Gramene" id="ABO98289">
        <property type="protein sequence ID" value="ABO98289"/>
        <property type="gene ID" value="OSTLU_9623"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9623"/>
    <dbReference type="eggNOG" id="KOG2017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_13_3_1"/>
    <dbReference type="OMA" id="KKLVVMC"/>
    <dbReference type="OrthoDB" id="498241at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050229">
        <property type="entry name" value="GlpE_sulfurtransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43031">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43031:SF1">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULPHIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="98" mass="10852" checksum="B9F45C1B4210DD13" modified="2007-05-15" version="1" fragment="single">PWANIDVSALKDMLDSASDDDTMFVDVRERDEWDAARLPRFELKPLSAAGEWLETLPRDKKLVVMCKGGVRSEKACAALAQCGYDDLVNVEGGIMTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S406</accession>
    <name>A4S406_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PLAC8 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420186.1">
        <property type="nucleotide sequence ID" value="XM_001420149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S406"/>
    <dbReference type="GeneID" id="5003971"/>
    <dbReference type="Gramene" id="ABO98479">
        <property type="protein sequence ID" value="ABO98479"/>
        <property type="gene ID" value="OSTLU_26237"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26237"/>
    <dbReference type="HOGENOM" id="CLU_998872_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="30234" checksum="C598912F0BE25EE3" modified="2007-05-15" version="1">MSGREGVLGEPPLIETLDEPPIGNEACPQTSANPDAVVLGGIPLDDETPAPGERAKTGTPSASSTHGRNVMHEDKTPFLNSNEQLSSAPMTQTMSAEREELTMDPIYAFYTTGDSIYSCCFAGCSHGDTVVAHDLLRESPASFDTPAGQEFQKTNDITCIRGCWKPALKITAFPLVAQIVHQVYPLTATSSLACINFHTALSCLSIASVAYLGGSHRKRMIEAHGLREPPCNLGCCALSPPFNPYCCWFWCVPCAAAQEHKAMKRMLRHRAIDVTHDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S490</accession>
    <name>A4S490_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420050.1">
        <property type="nucleotide sequence ID" value="XM_001420013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S490"/>
    <dbReference type="GeneID" id="5003921"/>
    <dbReference type="Gramene" id="ABO98343">
        <property type="protein sequence ID" value="ABO98343"/>
        <property type="gene ID" value="OSTLU_25186"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25186"/>
    <dbReference type="HOGENOM" id="CLU_603254_0_0_1"/>
    <dbReference type="OMA" id="TNWKTCK"/>
    <dbReference type="OrthoDB" id="10482866at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="454" mass="49649" checksum="F73AEAE79130611A" modified="2007-05-15" version="1">MRRGMTRTTTSQRRASTSGRRDAFEGAYEREDDDDGTYDDADDADSDGEWMDYDDEVDRVSFLASTTFRSSAASSERRARAARRRGGDSERCGCASGAVAACLLVLGVSSIGRASYSNVLARQREAYARVVEAWDDGEREKFARVKFEWALVADAEQPTWVSTRAVTTRTKEGVNFGVATYEPLRYALEGGDLLEAFGIPSLIRDGVLDARDAPDIHDILHPDADIHSYTSGYNNTAVMGALMGTRALRLRINDGAQALDVRNVELFTKEFLPITNWKTCKYQHAGYPNHGGCDTYSVIDRICLKLQATSGGEWDLDTSGGGAGCEARSSEDGADAYDPIIRHRIVAPVTGAYPALSVVRKTLALTRDAETAILLRASDDPHLWLLNATDGTAAFAAAQSRLNAAGIAFVVLAAVFSIPAICLLLPMLYEKYTVKGRYGRRSRRVEPVPLRDMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S493</accession>
    <name>A4S493_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_17201</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420391.1">
        <property type="nucleotide sequence ID" value="XM_001420354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S493"/>
    <dbReference type="STRING" id="436017.A4S493"/>
    <dbReference type="GeneID" id="5004418"/>
    <dbReference type="Gramene" id="ABO98684">
        <property type="protein sequence ID" value="ABO98684"/>
        <property type="gene ID" value="OSTLU_17201"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17201"/>
    <dbReference type="eggNOG" id="ENOG502QVVW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_809833_0_0_1"/>
    <dbReference type="OrthoDB" id="406981at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017095">
        <property type="term" value="F:heparan sulfate 6-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010635">
        <property type="entry name" value="Heparan_SO4-6-sulfoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12812">
        <property type="entry name" value="HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12812:SF0">
        <property type="entry name" value="HEPARAN-SULFATE 6-O-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="39611" checksum="C2A64C1F1BF256DE" modified="2007-05-15" version="1">MRGRKMHECDKLATSWIDEQRGAHERRVRARDDDAQRRFLYFLHIPRTAGRSFHWCFLKPSFKDHELCGNQYTGLRIDPREPTCEFLATHDDYSLIERFTEQPRVVTMLRKPSARALSSYEFSIEVAARSFGKEPVNTTRVQTRDVWPWSVLTRFMDDELRSYDDAVNADGRNELSISNVYDNALYTPFEDWAEMKMVHDDIHNGQFFQLLGLTNNTDDAVEPRAAELRECALWRGTKASKMMMDYAKERLEHEVDVLALHERLDESIELAARQLDLPLSANANFADPTQIDAQNVKSRISKVGTSFKSDDASDCVDVVGFSFRFSKLKTMTTGQRILKGFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4C3</accession>
    <name>A4S4C3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420244.1">
        <property type="nucleotide sequence ID" value="XM_001420207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4C3"/>
    <dbReference type="GeneID" id="5004313"/>
    <dbReference type="Gramene" id="ABO98537">
        <property type="protein sequence ID" value="ABO98537"/>
        <property type="gene ID" value="OSTLU_26360"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26360"/>
    <dbReference type="HOGENOM" id="CLU_1301506_0_0_1"/>
    <dbReference type="OrthoDB" id="10602599at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="212" mass="23241" checksum="A708F8D37E48D88E" modified="2007-05-15" version="1">MDDDALARPAVFVEAERRASAEAERRAREARARREEAEAEEEAEAEDDDEIDSDATDDEEAFDWRAVRANGDGNDGTTAREVEADAEASARRSATLPTRNLAKTQPWRARLPNFTPVRELPPQSFHDGELVFVDYEAQFGGPRSAASKAFARREARAFGGVGARDRAAASTAPTAAVPRWFTDERGRKTFVDARGKSLVGKAAYAASQRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4I8</accession>
    <name>A4S4I8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lhcq-like</name>
        <name evidence="9" type="ORF">OSTLU_88576</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420273.1">
        <property type="nucleotide sequence ID" value="XM_001420236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4I8"/>
    <dbReference type="STRING" id="436017.A4S4I8"/>
    <dbReference type="GeneID" id="5004341"/>
    <dbReference type="Gramene" id="ABO98566">
        <property type="protein sequence ID" value="ABO98566"/>
        <property type="gene ID" value="OSTLU_88576"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88576"/>
    <dbReference type="eggNOG" id="ENOG502QQ8A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057943_10_0_1"/>
    <dbReference type="OMA" id="FEVLHAR"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="365" mass="38974" checksum="B60A8CA76A0802B5" modified="2007-05-15" version="1">MLSRGLVSTSRASVARARAPARQQRATTSRRASIVRRTAARATNDDDKASSSQDVPDDEPTPAVGDTDVNSALGDVISSPLFYVTFGVAGGVGLVRALGENASFLLSAAPVVLLTVISKTSFGESLMKNIDDQRPALVAEKARRENERARARERSSLYGARRVKFLGDAEYEYPAHLDGSLCGDAGFDPLGLGKDDLPRMRELELLHARWAMLGIVGVAVPELLERYGVADLGEPVWWKVGAAKMNSDVSLDYFGLQGFHIAGGSGIAIIAACQVVLMGGPEYARYVGIDSLEPVGVYLPGDKDYPGGAPFDPFKISDDADEFEKQKVMEIKHGRLAMIAMLGVAAQAFVTRAGPIENLASVFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4U7</accession>
    <name>A4S4U7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DMT family transporter: UDP-galactose/UDP-glucose</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_26534</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420499.1">
        <property type="nucleotide sequence ID" value="XM_001420462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4U7"/>
    <dbReference type="GeneID" id="5004386"/>
    <dbReference type="Gramene" id="ABO98792">
        <property type="protein sequence ID" value="ABO98792"/>
        <property type="gene ID" value="OSTLU_26534"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26534"/>
    <dbReference type="eggNOG" id="KOG1582">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059268_0_0_1"/>
    <dbReference type="OMA" id="KWINYAT"/>
    <dbReference type="OrthoDB" id="497696at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF8">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="37310" checksum="35358E2CB60FC2C0" modified="2007-05-15" version="1">MSENAAFAVAGTCAIVFIGASCYFEEYVYKSLPNFDYYWTVALAELMVFALISSASSIADGTLFAKRKAPLELYALQALLLAAYSAVGKLCYKWINYATGTVLRSSKLVFTMAISAVWLRRTYKPHQVVAASLLVVAVAFFGIAERELGSNEATMPTPATATTNDGEAVLGLSEDVKLALGFGLSVVAIFLGSLQTNVSEHAMRNYGAGVRENILYTNAIGTVFAFLFVVIFEGSGSITYLRTVKGAFVLLFARSVTFYFGAYFFSTLTRHFGATSATAVTTVRKALTVISSFILFPKDKPFAGFFVYGLFFFLLSVLAESSLHIRAFFHRVRAGRRGEYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4S515</accession>
    <name>A4S515_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_17423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420364.1">
        <property type="nucleotide sequence ID" value="XM_001420327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S515"/>
    <dbReference type="STRING" id="436017.A4S515"/>
    <dbReference type="GeneID" id="5004477"/>
    <dbReference type="Gramene" id="ABO98657">
        <property type="protein sequence ID" value="ABO98657"/>
        <property type="gene ID" value="OSTLU_17423"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17423"/>
    <dbReference type="HOGENOM" id="CLU_805083_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="345" mass="35056" checksum="9AB1629248A32B9D" modified="2007-05-15" version="1">MARHRRDLNHGIVLNTESERIARKWRARQPNRVQQNQRYLPVETKTAKLDLAADSAADSAADWVVDWVADWAADWAADWAADSAADWAADWAADWVVDWVADWAADWAADSAADSAEDLVADSAEDLVADSAADSATDSAVDLVVDSAVHLVADSAVDLVADSAVDLVVDSAVNLVADSVADSAADSAADSAADSAADLLATPKALVEIAVVADLAADLAADSAVDLVVDLAADSAADSAADSAVDLVVDSAVDLVADSAVDSMVDWAVDLVADSAVDLVVDSAAVDSAVDLVATPKALVEIAVVADSAADLAVDSAADWAADLSVDSAADSAADSAVDSAVPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S585</accession>
    <name>A4S585_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420729.1">
        <property type="nucleotide sequence ID" value="XM_001420692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S585"/>
    <dbReference type="STRING" id="436017.A4S585"/>
    <dbReference type="GeneID" id="5004793"/>
    <dbReference type="Gramene" id="ABO99022">
        <property type="protein sequence ID" value="ABO99022"/>
        <property type="gene ID" value="OSTLU_26672"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26672"/>
    <dbReference type="eggNOG" id="ENOG502QYF3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1901683_0_0_1"/>
    <dbReference type="OMA" id="TRASECD"/>
    <dbReference type="OrthoDB" id="431485at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="130" mass="14624" checksum="B5198573992F6AAC" modified="2007-05-15" version="1">MNDDDVDAMMEKAFGWRGQGYWRNTKVREVPTAADVTARVAFLESIGVTTRASECDLAKIVKKQPEILACDVEQLTAATEHIEKNYFMKRDTRNFVKYVVRVPQALGNNLDCAGEGKACLGECNRCWARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5C9</accession>
    <name>A4S5C9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Clathrin/coatomer adaptor adaptin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_39338</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420751.1">
        <property type="nucleotide sequence ID" value="XM_001420714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5C9"/>
    <dbReference type="STRING" id="436017.A4S5C9"/>
    <dbReference type="GeneID" id="5004851"/>
    <dbReference type="Gramene" id="ABO99044">
        <property type="protein sequence ID" value="ABO99044"/>
        <property type="gene ID" value="OSTLU_39338"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39338"/>
    <dbReference type="eggNOG" id="KOG1062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003824_3_2_1"/>
    <dbReference type="OMA" id="QSHYRED"/>
    <dbReference type="OrthoDB" id="29308at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030124">
        <property type="term" value="C:AP-4 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017109">
        <property type="entry name" value="AP4_complex_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037097">
        <property type="entry name" value="AP4_complex_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="5">
        <location>
            <begin position="41"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="630" mass="70150" checksum="C2AFEBF2FC871A91" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5D0</accession>
    <name>A4S5D0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420752.1">
        <property type="nucleotide sequence ID" value="XM_001420715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5D0"/>
    <dbReference type="GeneID" id="5004821"/>
    <dbReference type="Gramene" id="ABO99045">
        <property type="protein sequence ID" value="ABO99045"/>
        <property type="gene ID" value="OSTLU_26719"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26719"/>
    <dbReference type="HOGENOM" id="CLU_662909_0_0_1"/>
    <dbReference type="OMA" id="CCCFEPL"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="45731" checksum="997DC78B8CC495E3" modified="2007-05-15" version="1">MFAALSARARARQNDDAIPAWQSKAKSRKRARDDGDKSANDDDSRASETGTIYLTVEWLSRTRGRSNELFAETPQCADVAIEVSESVTGRALVEACVQLPPGATDAMSLLQWGNLKLDDGVLHGQEDGGWSLDVRATPPVRLKLTVPNGTLLKHPALVKETRGKQSVPKELLSDANALKEDLNDPSSVSKETDKAEVVERSRRALHPGRTDDHGIAALLNDHKVFYGKKANMGSFVDVGSGCGSLAAGLARAFPGINVCGIECQDELINQSRLRFRDVDFIHDQAENVLHTCRSAKVVLATTQNFDYETTNYILRVAAELPLLTHLIINEPYLCRPACRTNLKLCCCFEPLETREIKTHWGNSTLSFTIYKRHVRWPYGANALPRGADTAVALMEGNVNEMFLKKTDNSQENSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5J3</accession>
    <name>A4S5J3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="4">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">OSTLU_39441</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="4"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420619.1">
        <property type="nucleotide sequence ID" value="XM_001420582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5J3"/>
    <dbReference type="STRING" id="436017.A4S5J3"/>
    <dbReference type="GeneID" id="5004648"/>
    <dbReference type="Gramene" id="ABO98912">
        <property type="protein sequence ID" value="ABO98912"/>
        <property type="gene ID" value="OSTLU_39441"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39441"/>
    <dbReference type="eggNOG" id="KOG0237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027420_3_1_1"/>
    <dbReference type="OMA" id="KATVCKY"/>
    <dbReference type="OrthoDB" id="2018833at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000031">
        <property type="entry name" value="Phosphoribosylamine--glycine ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000006">
        <property type="entry name" value="Phosphoribosylamine--glycine ligase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000006">
        <property type="entry name" value="phosphoribosylamine--glycine ligase, chloroplastic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.600.10:FF:000001">
        <property type="entry name" value="Trifunctional purine biosynthetic protein adenosine-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="entry name" value="Phosphoribosylglycinamide synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PHOSPHORIBOSYLAMINE--GLYCINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINE--GLYCINE LIGASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01209">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="20">
        <location>
            <begin position="155"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00079592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ABO98912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="477" mass="49139" checksum="C611F855FF5D60ED" modified="2007-05-15" version="1">MTTTTTARTRAGRGTRATRTARTTRVVRFVATRATRDGVARASSAKTNVLVVGGGGREHALCWRLASSASAGTLYCAPGNAGIARERGVETVTLNESDHAAVVGFCRERSIGLVVVGPEAPLVDGLADALAAAGVPVFGPSKSAARLEGSKAFMKDLCAKYKIPTAEYAKFTDAAKAKAYIESKGAPIVVKTDGLAAGKGVIVAMEIEDALNAVDDMLSGAMFGSAGEEIVVEEFLDGEEASFFAVVGGGKAVALASAQDHKRVGDGDTGLNTGGMGAYSPAPVVTPEITDVVMRDIIKPTVDGMAAEGCPFTGVIFAGLMISKDGTVKLLEHNIRFGDPECQVLMARLTSDLTALLLAAATGTLENAEVTWSDDSAVVVVMAAEGYPGSYAKGEKITNLDAAGAIDGVKVLHAGTASDADGDVVSSGGRVLGVTAYGSSITEAAERAYEAVDVIEWPGGFTRRDIGWRAIAREKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5N4</accession>
    <name>A4S5N4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_93535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420640.1">
        <property type="nucleotide sequence ID" value="XM_001420603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5N4"/>
    <dbReference type="GeneID" id="5004758"/>
    <dbReference type="Gramene" id="ABO98933">
        <property type="protein sequence ID" value="ABO98933"/>
        <property type="gene ID" value="OSTLU_93535"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93535"/>
    <dbReference type="HOGENOM" id="CLU_630723_0_0_1"/>
    <dbReference type="OMA" id="HEDIAPT"/>
    <dbReference type="OrthoDB" id="515841at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="378"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="435" mass="48424" checksum="FC6A8642813D0B0B" modified="2007-05-15" version="1">MQRRERALWSLEHALSSPEIPLDVKVEVKNACAASLDDETLASCDSLVVRLFDVLSRARDALIAGEGAMRGNSARACADALHAVTTRRDAPETLKRRGKDVVEALRGEWCFAAARETRNEGGTSPVRGWKAMENFWMRWRTLTIGDGGLGDGSALGTKAKRTYDMVERAESDMRLPSDWESRVPTAEDIAQDLQTLFTDLCESGELMSFLSVVRNDISSGRYKVQVRGDGRVARQSGAMTDSIGLEPHLEGLGRKLRAEATRHRQEPPLGALTAVPESFSSPPKRVHIAAQRKKNARTVEWDSQNDQPDDNDKEEEDKDEHEDIAPTQQTPRAKPSPLTNLSWEEVGYRTPRANLPAISPAPRAALKSPSTRKKLHVKVKWTDAEVTCLHLGVQKYGIGNWAKILNDPTLTNGFHTSRTGVHLKDKWRTIQRQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="116" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5R3</accession>
    <name>A4S5R3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_51045</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420654.1">
        <property type="nucleotide sequence ID" value="XM_001420617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5R3"/>
    <dbReference type="STRING" id="436017.A4S5R3"/>
    <dbReference type="GeneID" id="5004772"/>
    <dbReference type="Gramene" id="ABO98947">
        <property type="protein sequence ID" value="ABO98947"/>
        <property type="gene ID" value="OSTLU_51045"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51045"/>
    <dbReference type="eggNOG" id="KOG0892">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000178_9_1_1"/>
    <dbReference type="OMA" id="SSHTHEE"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="20"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="10">
        <location>
            <begin position="352"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="384" mass="43725" checksum="F703DCCDE830A230" modified="2007-05-15" version="1">MAVDPACKYPDGSFPYFLHFADSTRLVGGINEPKLLGCHGSDGQVYRQLAKSGNDDLRQDAVIQQFFGLVNTLLKQNTSTNSRSMRIRTYKVIPFSPEAGLLEWVDETVLLSNYLIRDKKGAHERYRPHDMKSRDISQMMRDAVTAEAQHKMYEEVCENFKPVMHNFFLEHYPDPSNWFERRVAYSRSCAVNSIVGYVIGLGDRHSSNIMIDKWTAEFIHIDFGVTFEQGLTLKTPERVPFRLTRDIVDGMGACGVEGIMRRCCEETMKVLRSNRDALTTIIAVLVHDPILKWAVGGRRQNANIFRTTTMFGTIAYALNPDREVVPSDEGNLDAERALMRVKQKLDGYEDGELRSIEGQVQQLLHDARDPHKLAVMYAGWAPWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6F2</accession>
    <name>A4S6F2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_41563</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="8">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420934.1">
        <property type="nucleotide sequence ID" value="XM_001420897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6F2"/>
    <dbReference type="STRING" id="436017.A4S6F2"/>
    <dbReference type="GeneID" id="5005140"/>
    <dbReference type="Gramene" id="ABO99227">
        <property type="protein sequence ID" value="ABO99227"/>
        <property type="gene ID" value="OSTLU_41563"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41563"/>
    <dbReference type="eggNOG" id="KOG0347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_1_1"/>
    <dbReference type="OMA" id="RTANCID"/>
    <dbReference type="OrthoDB" id="4310724at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="49"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="247"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="394" mass="42911" checksum="CE1ACF55348FFA4A" modified="2007-05-15" version="1" fragment="single">MSAVVDGVDLDRGCDVSAWFEFDLHPLIMRAIQDCGFTTPTPIQRECLLPATKGRCDIIGAAQTGSGKTLAFALPILQRLLSQGIDVLRALIVAPTRELALQVCAMMRAVAVYTKIDVCPVVGGMSKEKQERLLNRKPAVIVATPGRMWDTMQSGHEHLTELSALSFFVLDEADRMVERGHFSELTSIIQNIPQPPRIKRPGGAAKLTSAVPFYGRVKMVDLTTKERKGGAVAKSIAESALECTEDDRDSLLYYLLSAHPGMTIVFVNAISCLRRVVALLKILRVPVEGLHAGMQQRARLKALDRFKAAAAAADKGDRHAHSVLVATDVAARGLDVKGVELVIHYQIPLSADTYIHRSGRTGRADKLGAAVSLVTPKDRARYYSLLKSLNRDGP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-11-13" modified="2025-04-09" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Z4</accession>
    <name>RL37A_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Large ribosomal subunit protein eL43</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>60S ribosomal protein L37a</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">RPL37a</name>
        <name type="ORF">OSTLU_13231</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421182.1">
        <property type="nucleotide sequence ID" value="XM_001421145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6Z4"/>
    <dbReference type="SMR" id="A4S6Z4"/>
    <dbReference type="STRING" id="436017.A4S6Z4"/>
    <dbReference type="EnsemblPlants" id="ABO99475">
        <property type="protein sequence ID" value="ABO99475"/>
        <property type="gene ID" value="OSTLU_13231"/>
    </dbReference>
    <dbReference type="GeneID" id="5005370"/>
    <dbReference type="Gramene" id="ABO99475">
        <property type="protein sequence ID" value="ABO99475"/>
        <property type="gene ID" value="OSTLU_13231"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13231"/>
    <dbReference type="eggNOG" id="KOG0402">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141199_1_0_1"/>
    <dbReference type="OMA" id="ESAHAHC"/>
    <dbReference type="OrthoDB" id="564175at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000002">
        <property type="entry name" value="60S ribosomal protein L37a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_eL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050522">
        <property type="entry name" value="Ribosomal_protein_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00280">
        <property type="entry name" value="eL43_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_0000308952" description="Large ribosomal subunit protein eL43">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="92" mass="10170" checksum="C6B887514ADB49B7" modified="2007-05-15" version="1">MAKRTKKVGIVGKYGTRYGASLRKVVKKQEVSQHSKFFCDFCGKYGMKRKAVGIWSCKGCNKTKAGGAYSLNTGGSVTVRSTIRRLREATEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S728</accession>
    <name>A4S728_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_27330</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="2">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421201.1">
        <property type="nucleotide sequence ID" value="XM_001421164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S728"/>
    <dbReference type="STRING" id="436017.A4S728"/>
    <dbReference type="MEROPS" id="T01.A10"/>
    <dbReference type="GeneID" id="5005530"/>
    <dbReference type="Gramene" id="ABO99494">
        <property type="protein sequence ID" value="ABO99494"/>
        <property type="gene ID" value="OSTLU_27330"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27330"/>
    <dbReference type="eggNOG" id="KOG0175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_7_3_1"/>
    <dbReference type="OMA" id="NLGMAMQ"/>
    <dbReference type="OrthoDB" id="37597at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03761">
        <property type="entry name" value="proteasome_beta_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000034">
        <property type="entry name" value="Proteasome subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="7 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="32193" checksum="AE5CF8DA4A0EB20C" modified="2007-05-15" version="1">MNGPTLDFSFLDATARGSMASKHVDESLDAIDGNMHECNFKAPAVEDFEGFQREVINYVKPNHGTTTLAFIFEHGIVVAVDSRASQGPYISSQTVKKVIEINPFLLGTMAGGAADCQFWQRNLGIQCRLHELENGKRITVRAASKLLANTLYSYKGKGLSMGTMVAGWDLNGPGLYYVDSEGTRLKGQRFSVGSGSLFAYGVLDQGYKWDLTVEEACELGRRAIYHATFRDAFSGGTVSVYHVGANGWTKVTGDDVGELHFSYYPATPVDDVDAHCGGEGKKEAEARAATEASAMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7A3</accession>
    <name>A4S7A3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_43289</name>
        <name evidence="2" type="ORF">OSTLU_43396</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421421.1">
        <property type="nucleotide sequence ID" value="XM_001421384.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421452.1">
        <property type="nucleotide sequence ID" value="XM_001421415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7A3"/>
    <dbReference type="STRING" id="436017.A4S7A3"/>
    <dbReference type="GeneID" id="5005318"/>
    <dbReference type="GeneID" id="5005354"/>
    <dbReference type="Gramene" id="ABO99714">
        <property type="protein sequence ID" value="ABO99714"/>
        <property type="gene ID" value="OSTLU_43396"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99745">
        <property type="protein sequence ID" value="ABO99745"/>
        <property type="gene ID" value="OSTLU_43289"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43289"/>
    <dbReference type="KEGG" id="olu:OSTLU_43396"/>
    <dbReference type="eggNOG" id="KOG0620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016428_7_0_1"/>
    <dbReference type="OMA" id="SADYRIM"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
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        <property type="component" value="Chromosome 14"/>
    </dbReference>
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        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
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        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF37">
        <property type="entry name" value="2',5'-PHOSPHODIESTERASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="91"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="401" mass="44420" checksum="BF1C8B0116AFC077" modified="2007-05-15" version="1">MVGYPLPATAHGLEFCQHDEVDWRWYADGEIVGQGRVYTPTKEDFGKRLAVEALDERFEFTNVVTRLGVDRSEALRRLEPSAETSADYRIMTYNVLADAYAHTWGTMFPYFDTALAKVERRLQLVLEDILRSKADVVALQEVDKKYHETLFVPVLTANGYIATDWVGKSGQTLEGCAMFFALSKFESIEREEAIKLTEIGDKALRRWIADDDNAELAMALKKITSIAQLARVKVRASGKSLCVGNTHLFFHPGAMHLRVLQAHEFTTRATAFAAGDPLVLCGDFNGEPEDGVIRYLTKGEISASDEDWVRGSLFRAVPIGCGAHLRTARPLFSAGGFLEWTNYVGGFVGALDYVWCSTSDFASRATSPLPDMSAVLAHTALPNAQFPSDHIPVIVDVDLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7L8</accession>
    <name>A4S7L8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421476.1">
        <property type="nucleotide sequence ID" value="XM_001421439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7L8"/>
    <dbReference type="GeneID" id="5005268"/>
    <dbReference type="Gramene" id="ABO99769">
        <property type="protein sequence ID" value="ABO99769"/>
        <property type="gene ID" value="OSTLU_18137"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18137"/>
    <dbReference type="HOGENOM" id="CLU_840423_0_0_1"/>
    <dbReference type="OrthoDB" id="10300651at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="331" mass="37344" checksum="964DD8B41EA59D00" modified="2007-05-15" version="1">MTDSVAHASPTWRTNSLDPSLQPDWMNGTAESEAVKTAEDDLERSYKNKPFFKDPCYEKFARSRDEYDKPTPDGLEEFKRLLRASYLRTVERIDKDIRVLEAQLQDENISETRRSVIPQHIEDTRAKLKEKDNSLNAMCADVDAVIADLKGLPDKIADIKEHASEQLQQHKRKRTSVSLERNLEELSDALRSYEAKMEQQRLTLWNYRGNYGSCPPQYVGHRSGSSSFIVHPVGVIGCDGSNLSVDGYVNYDGYGQCNVPKWQPEWGPEKQFCACKSFQDWYNKVGAQDLLYSALRGVEGALKALSGSGDDTSSLRRRMGDANLDEASTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7U2</accession>
    <name>A4S7U2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_27617</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRN7/TAF1B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421333.1">
        <property type="nucleotide sequence ID" value="XM_001421296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7U2"/>
    <dbReference type="STRING" id="436017.A4S7U2"/>
    <dbReference type="GeneID" id="5005417"/>
    <dbReference type="Gramene" id="ABO99626">
        <property type="protein sequence ID" value="ABO99626"/>
        <property type="gene ID" value="OSTLU_27617"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27617"/>
    <dbReference type="eggNOG" id="KOG1988">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_371902_0_0_1"/>
    <dbReference type="OMA" id="IIDEHIC"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048538">
        <property type="entry name" value="Rrn7_cyclin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048540">
        <property type="entry name" value="Rrn7_cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033599">
        <property type="entry name" value="TAF1B/Rrn7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021752">
        <property type="entry name" value="TF_Rrn7_Zf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576:SF2">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20645">
        <property type="entry name" value="Rrn7_cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20644">
        <property type="entry name" value="Rrn7_cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11781">
        <property type="entry name" value="Zn_ribbon_RRN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRN7-type" evidence="11">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B N-terminal cyclin" evidence="12">
        <location>
            <begin position="110"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B C-terminal cyclin" evidence="13">
        <location>
            <begin position="265"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO99626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="748" mass="81874" checksum="3F8F22C88E2820D7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S882</accession>
    <name>A4S882_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27757</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421717.1">
        <property type="nucleotide sequence ID" value="XM_001421680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S882"/>
    <dbReference type="STRING" id="436017.A4S882"/>
    <dbReference type="GeneID" id="5005854"/>
    <dbReference type="Gramene" id="ABP00011">
        <property type="protein sequence ID" value="ABP00011"/>
        <property type="gene ID" value="OSTLU_27757"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27757"/>
    <dbReference type="eggNOG" id="ENOG502QPIP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052245_0_0_1"/>
    <dbReference type="OMA" id="QLRWLEY"/>
    <dbReference type="OrthoDB" id="10262032at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42866">
        <property type="entry name" value="3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42866:SF2">
        <property type="entry name" value="3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="284"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="37757" checksum="9A2951A5BC4B20DA" modified="2007-05-15" version="1">MSANFVLGVVSAPYEDGEDDQFAGKALMIVHGKPAFARAAESMKRCARLDRVVVATDDYRIVETAKEYGIETVLVAQDARRTASTYARQAAKLTGGGWDFVVTLKVDECLIDADSVDACVMEMEANADEWCVASTCVAATDPARFESETRPRCVFDKQGFALYLTRAVIPAIGSKPRETMTGELDLTPTKRETKNRLDAAAMHWHVLGCSCYDAMYLRTLVDDSNDTTPLQRMENIEALNTLENGYKIKVCPVNNQTPALRAPEDVAVLEEVLRARVVQNAASAVKKKRASPKSALPRHVKRDKSRAARVRAEPSASEVSDAPSPSAGSPSATDDVPSPRAGDRTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8E3</accession>
    <name>A4S8E3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Brix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_40469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421605.1">
        <property type="nucleotide sequence ID" value="XM_001421568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8E3"/>
    <dbReference type="STRING" id="436017.A4S8E3"/>
    <dbReference type="GeneID" id="5005691"/>
    <dbReference type="Gramene" id="ABO99898">
        <property type="protein sequence ID" value="ABO99898"/>
        <property type="gene ID" value="OSTLU_40469"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40469"/>
    <dbReference type="eggNOG" id="KOG2963">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026936_2_1_1"/>
    <dbReference type="OMA" id="RRCMLIN"/>
    <dbReference type="OrthoDB" id="10261452at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045112">
        <property type="entry name" value="PPAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661">
        <property type="entry name" value="PETER PAN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661:SF5">
        <property type="entry name" value="SUPPRESSOR OF SWI4 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="29"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="410" mass="46591" checksum="55E7DA0160C76016" modified="2007-05-15" version="1">MAKTRRRKRRTHVDADAGGGSKGKDADAPRTFVFTRGRMADAVKDLSEDLRKVMEPHTARNLKESKSNKLKDFVQVSGPLGISHFLMLSSSDASKYFKICRTPRGPTLTFKIHSFSLSNEVAATQKNPRNPAKAFLSPPLVILNNFGDEAHQKLATITFQNMFPPINVRKVKLSTCQRAVLVDYDAKTKRFQFRHYSINAAPVGANKKLKKLLQSRNAPDLGDTQDVSEFFDKRVGDASDSEGSDDESRRVHLTQDFNRVAHADSTSKIILNEIGPRMELELVKVEEGMCDGRVLYHAYVKKTAEEVKTLEQKKVEREKLRKRRRVEQEANVKRKAREKEIKADAERARQGKSKKKSSAVDEFGNVRDVEGEAEDDAKWAAAFEREEKEWREGDVYDERSGKTKRKRHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8L0</accession>
    <name>A4S8L0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421641.1">
        <property type="nucleotide sequence ID" value="XM_001421604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8L0"/>
    <dbReference type="GeneID" id="5005722"/>
    <dbReference type="Gramene" id="ABO99934">
        <property type="protein sequence ID" value="ABO99934"/>
        <property type="gene ID" value="OSTLU_27886"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27886"/>
    <dbReference type="HOGENOM" id="CLU_2626417_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="78" mass="8112" checksum="19514C4116F135BD" modified="2007-05-15" version="1">MEAADAARVEAEARARRAAAASEASEAKTAKNRAKRAKAKAKRAAKRRRGGGGATIGEAKADEEEEEEEAEATATALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8U8</accession>
    <name>A4S8U8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FBP12</name>
        <name evidence="7" type="ORF">OSTLU_27975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8U8"/>
    <dbReference type="STRING" id="436017.A4S8U8"/>
    <dbReference type="GeneID" id="5006111"/>
    <dbReference type="Gramene" id="ABP00115">
        <property type="protein sequence ID" value="ABP00115"/>
        <property type="gene ID" value="OSTLU_27975"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27975"/>
    <dbReference type="eggNOG" id="KOG0544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_12_2_1"/>
    <dbReference type="OMA" id="ETITVHC"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
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        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
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        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="30"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="12953" checksum="77FF851246C98B60" modified="2007-05-15" version="1">MSAFVPVPGCATRFRVLNQAPPSAPVVERGDVVVVHAKGVVKETQKTFWSTKDPGQKPFEYTAGVGGVITGWDRGCLGARVGETRELDIPASEGYGAGGFPAWGIPPNGALVFEIEVLSVRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8X5</accession>
    <name>A4S8X5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_10629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421966.1">
        <property type="nucleotide sequence ID" value="XM_001421929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8X5"/>
    <dbReference type="STRING" id="436017.A4S8X5"/>
    <dbReference type="GeneID" id="5006125"/>
    <dbReference type="KEGG" id="olu:OSTLU_10629"/>
    <dbReference type="HOGENOM" id="CLU_000134_45_4_1"/>
    <dbReference type="OrthoDB" id="71307at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="79" mass="8480" checksum="7753E64883DC1F98" modified="2007-05-15" version="1" fragment="single">LVRRLIAEGVDVNEVDGAGSTPIMCAAYEGWCEGVDALVELGAKVNASNNAGDTAYQWAENIQDEEMMEKLKQHGADPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S905</accession>
    <name>A4S905_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HMGB3502</name>
        <name evidence="8" type="ORF">OSTLU_28032</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="protein sequence ID" value="ABP00143"/>
        <property type="gene ID" value="OSTLU_28032"/>
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    <dbReference type="eggNOG" id="KOG1946">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1104042_0_0_1"/>
    <dbReference type="OMA" id="IWPLVQE"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
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        <property type="entry name" value="DEK_C"/>
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    <dbReference type="InterPro" id="IPR009071">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEK-C" evidence="7">
        <location>
            <begin position="2"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="97"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="DM2" evidence="6">
        <location>
            <begin position="187"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="97"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="31466" checksum="2A41B3D0C2C9D1BE" modified="2007-05-15" version="1">MEDTQRQIARLLPDIIRGADLEKATVRTLQKSLEDSLGRDLGEHKNFIRAEVEHFLKGAVTKKRAALDEEGSKGKKAKAQKKTGRGKTKELVDPTRPKGPKGAYMCFVSARRSQIKDANPDMTFPDIARELGVEWKTMSEASRHRYEQMAELDKDRYTREMLSYVPLSDEKMQELREQQSRRKAAGGLQVMYHCSPELTAFLGGAKTINRKELTTRIWKYFREHNLMDPINKRFIVPDTKLSKLLKLQDGERFLAFTVSRYLNPHLVKKVESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4S922</accession>
    <name>A4S922_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421990.1">
        <property type="nucleotide sequence ID" value="XM_001421953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S922"/>
    <dbReference type="GeneID" id="5006030"/>
    <dbReference type="Gramene" id="ABP00284">
        <property type="protein sequence ID" value="ABP00284"/>
        <property type="gene ID" value="OSTLU_28049"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28049"/>
    <dbReference type="HOGENOM" id="CLU_3017633_0_0_1"/>
    <dbReference type="OrthoDB" id="10447477at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673128" evidence="1">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="56" mass="6265" checksum="DD0963D4971DC701" modified="2007-05-15" version="1">MFAFSVLLFSVPPLLKLKHVLYPPEVEPEAWDYEAEIADLAPGGARRRQRADADAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S988</accession>
    <name>A4S988_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421894.1">
        <property type="nucleotide sequence ID" value="XM_001421857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S988"/>
    <dbReference type="GeneID" id="5006060"/>
    <dbReference type="Gramene" id="ABP00188">
        <property type="protein sequence ID" value="ABP00188"/>
        <property type="gene ID" value="OSTLU_28118"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28118"/>
    <dbReference type="HOGENOM" id="CLU_1655090_0_0_1"/>
    <dbReference type="OMA" id="HTNETTA"/>
    <dbReference type="OrthoDB" id="498809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="15956" checksum="0934E309D6605512" modified="2007-05-15" version="1">MTSVDALWEEVRDARSGQIYYWQTETDETTPLGAPRPTTYSALDPTMPAPTRSGTRAPPPSRDLGAAGGSAAGGFGSMIAQGAAWGMGSSLGHRAIGGMFGYGGYGGVGGVGGGEGAIGEAGGTEAPAPPDFGASEFDDDDGFGDGGSDGGSLFDFFSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9N2</accession>
    <name>A4S9N2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18662</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422096.1">
        <property type="nucleotide sequence ID" value="XM_001422059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9N2"/>
    <dbReference type="GeneID" id="5006258"/>
    <dbReference type="Gramene" id="ABP00413">
        <property type="protein sequence ID" value="ABP00413"/>
        <property type="gene ID" value="OSTLU_18662"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18662"/>
    <dbReference type="eggNOG" id="ENOG502QQ3J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031669_0_0_1"/>
    <dbReference type="OMA" id="CSMPDRV"/>
    <dbReference type="OrthoDB" id="497840at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="59934" checksum="6ABD76345B6E2339" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA82</accession>
    <name>A4SA82_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422336.1">
        <property type="nucleotide sequence ID" value="XM_001422299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA82"/>
    <dbReference type="GeneID" id="5006377"/>
    <dbReference type="Gramene" id="ABP00653">
        <property type="protein sequence ID" value="ABP00653"/>
        <property type="gene ID" value="OSTLU_93992"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93992"/>
    <dbReference type="HOGENOM" id="CLU_1613560_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18738" checksum="C9F6B98DAE52AF4B" modified="2007-05-15" version="1">MPSGCVYEMFSDNAKCNKTYIGSTTGSLRARLASHKYARHPIFKFGDADVRVLEKDIPAGELHQRKSAYMREKRDGLFNSRVAGRSQKHACHENVDGSPAYSRAQYTPKRVGGDGNYRQLSYYKQQAKRILRKTCLKNARARGTLPSKRSLDKYQFTVDELRGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAI8</accession>
    <name>A4SAI8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_94026</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422395.1">
        <property type="nucleotide sequence ID" value="XM_001422358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAI8"/>
    <dbReference type="GeneID" id="5006453"/>
    <dbReference type="KEGG" id="olu:OSTLU_94026"/>
    <dbReference type="HOGENOM" id="CLU_2175245_0_0_1"/>
    <dbReference type="OrthoDB" id="346910at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="3">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="110" mass="12780" checksum="0C19790BEADD2F54" modified="2007-05-15" version="1" fragment="single">LTEEQIATFLSEYEQHKDYETLKWRYVKRPGAQAARTEAWYGCYGPTQYLKHGENKEKAPVWREDGSIDYGGRAKWDAWDACKGMTEQEAKIAFVRAIRSALAAPHENFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAJ9</accession>
    <name>A4SAJ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_28596</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422445.1">
        <property type="nucleotide sequence ID" value="XM_001422408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAJ9"/>
    <dbReference type="STRING" id="436017.A4SAJ9"/>
    <dbReference type="GeneID" id="5006461"/>
    <dbReference type="Gramene" id="ABP00762">
        <property type="protein sequence ID" value="ABP00762"/>
        <property type="gene ID" value="OSTLU_28596"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28596"/>
    <dbReference type="eggNOG" id="ENOG502S805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_736482_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24183">
        <property type="entry name" value="FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24183:SF1">
        <property type="entry name" value="FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="320"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="376" mass="40442" checksum="BB204C5E822563F0" modified="2007-05-15" version="1">MFRVVVGDGAPLVDRDTGAPTTTEYYEVALVTDVPRYVAIARARAKTDDDDGNEKDCDDDRTTTREAVTFRAHKRYSAFEALHRALTARGRHEARLPTMPKKALVRTPAVRETRREGFQFILDAVGRDRELRACDEVVEFFTSAGTGGARERATLGVRGDAGGVEGSRTDGERDNGASAGEDDDDDDDDDAPIPRRGGGLESLLRSTMRVHGTSDALGERGEGEARRDDSSGSAFEEEEMRETTTRTTTMQTTPMATSSFMLNRATLLTTNGGVANGNDGLASYDASSAGAREAIKANDAIGLERLLDEHGVDVNAKDNSGMTLLHLACLFNRKHAVDALLRHGADATLRNAHGETASELAPPTLAFAIAKALKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAK2</accession>
    <name>A4SAK2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422405.1">
        <property type="nucleotide sequence ID" value="XM_001422368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAK2"/>
    <dbReference type="STRING" id="436017.A4SAK2"/>
    <dbReference type="GeneID" id="5006463"/>
    <dbReference type="Gramene" id="ABP00722">
        <property type="protein sequence ID" value="ABP00722"/>
        <property type="gene ID" value="OSTLU_18901"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18901"/>
    <dbReference type="HOGENOM" id="CLU_481817_0_0_1"/>
    <dbReference type="OMA" id="CEPALEY"/>
    <dbReference type="OrthoDB" id="10648292at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="566" mass="61888" checksum="1AC84FCBF8234DBC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB87</accession>
    <name>A4SB87_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_43597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422575.1">
        <property type="nucleotide sequence ID" value="XM_001422538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB87"/>
    <dbReference type="STRING" id="436017.A4SB87"/>
    <dbReference type="GeneID" id="5006789"/>
    <dbReference type="Gramene" id="ABP00892">
        <property type="protein sequence ID" value="ABP00892"/>
        <property type="gene ID" value="OSTLU_43597"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43597"/>
    <dbReference type="eggNOG" id="KOG0703">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023062_1_4_1"/>
    <dbReference type="OMA" id="TFICIEC"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000009">
        <property type="entry name" value="stromal membrane-associated protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF1">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="6">
        <location>
            <begin position="13"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="126" mass="14236" checksum="A475F93CE12E6509" modified="2007-05-15" version="1" fragment="single">MASDEREQQALQKRLLECLKRPENLTCAECAMRLPRWASTSLGVFFCTNCSGSHRGLGVHISKVKSTTLDKWTEAQVAHMERVGNAKANAYWEANVRAGVKPGATSGRDACERFIRDKYERQLYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBF0</accession>
    <name>A4SBF0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">16S rRNA (uracil(1498)-N(3))-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_6230</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>uridine(1498) in 16S rRNA + S-adenosyl-L-methionine = N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="3"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422606.1">
        <property type="nucleotide sequence ID" value="XM_001422569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBF0"/>
    <dbReference type="STRING" id="436017.A4SBF0"/>
    <dbReference type="GeneID" id="5006664"/>
    <dbReference type="Gramene" id="ABP00923">
        <property type="protein sequence ID" value="ABP00923"/>
        <property type="gene ID" value="OSTLU_6230"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6230"/>
    <dbReference type="eggNOG" id="ENOG502QPPV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067442_0_0_1"/>
    <dbReference type="OMA" id="RCITQWK"/>
    <dbReference type="OrthoDB" id="3465at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18084">
        <property type="entry name" value="RsmE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="RsmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046886">
        <property type="entry name" value="RsmE_MTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046887">
        <property type="entry name" value="RsmE_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00046">
        <property type="entry name" value="RsmE family RNA methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027:SF3">
        <property type="entry name" value="16S RRNA (URACIL(1498)-N(3))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20260">
        <property type="entry name" value="PUA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA small subunit methyltransferase E PUA-like" evidence="12">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA small subunit methyltransferase E methyltransferase" evidence="11">
        <location>
            <begin position="80"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="246" mass="25505" checksum="51D090821665020B" modified="2007-05-15" version="1" fragment="single">LHRFYVDADFARGAAVTLSREETRHATKALRLKPGDRLEVCDGRGTLGIARLCAVDGVGATVEVEEMVADALGSGTAWDVASAFGGLKGGRGDWLVEKCAELGARTLVPLLTTRSGAIGGGDRDGDKKRGREGRWGRVAHAASKQSLRVYGLQVAPPIGVEALCEEIAKDCGERLTLLAAAGAPPIADVARASGLDLRSGRIVIGPEGDFTDEELKAMIAAGARPVGLGSLRLRVETAAISALAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4SC14</accession>
    <name>A4SC14_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Triosephosphate isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_36521</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422959.1">
        <property type="nucleotide sequence ID" value="XM_001422922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SC14"/>
    <dbReference type="STRING" id="436017.A4SC14"/>
    <dbReference type="GeneID" id="5006927"/>
    <dbReference type="Gramene" id="ABP01318">
        <property type="protein sequence ID" value="ABP01318"/>
        <property type="gene ID" value="OSTLU_36521"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36521"/>
    <dbReference type="eggNOG" id="KOG1643">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024251_2_0_1"/>
    <dbReference type="OMA" id="PAFISIC"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000025">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP01318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28241" checksum="F39406EF62836A84" modified="2007-05-15" version="1" fragment="single">AAAQRRSVVVNAGTGKFIVGGNWKCNGTAESVKSLVKELNSGKIDADVDVYVAPPFVFIPRVQKELNNKNYAVAAQNCWVSAGGAFTGEVSADMLADADIPWVILGHSERRALCGETNEFVGEKTKYALSKGLKVALCIGETLEQREAGTTLDICRAQLKAVNDVVTAADWENIVIAYEPVWAIGTGKVATPDQAQEVHAGIRKWCADNISPAIASKIRIQYGGSVNAGNCDELAQKEDIDGFLVGGASLIGEAFVTICNSAKHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQE7</accession>
    <name>A4RQE7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_10519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415720.1">
        <property type="nucleotide sequence ID" value="XM_001415683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQE7"/>
    <dbReference type="STRING" id="436017.A4RQE7"/>
    <dbReference type="GeneID" id="4999908"/>
    <dbReference type="Gramene" id="ABO94012">
        <property type="protein sequence ID" value="ABO94012"/>
        <property type="gene ID" value="OSTLU_10519"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10519"/>
    <dbReference type="eggNOG" id="KOG0548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_44_4_1"/>
    <dbReference type="OMA" id="RPRTNQV"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="110" mass="12048" checksum="23314F04AEEF3A20" modified="2007-05-15" version="1" fragment="single">RERGNDAFDDGRFERAVGHYTRAIECRAGDAKSYSNRSACFLKMGKYSQALSDAERAVDIDGHYAKARTRVGAAALAMGNTDVAKRSFELALKLDPTSQTARDGLKACER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQJ1</accession>
    <name>A4RQJ1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chaperone, Hsp100 family, ClpB-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CLPB2</name>
        <name evidence="9" type="ORF">OSTLU_28681</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415741.1">
        <property type="nucleotide sequence ID" value="XM_001415704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQJ1"/>
    <dbReference type="STRING" id="436017.A4RQJ1"/>
    <dbReference type="GeneID" id="4999408"/>
    <dbReference type="Gramene" id="ABO94033">
        <property type="protein sequence ID" value="ABO94033"/>
        <property type="gene ID" value="OSTLU_28681"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28681"/>
    <dbReference type="eggNOG" id="KOG1051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_0_1"/>
    <dbReference type="OMA" id="FIVFEPL"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="96"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="524"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="8">
        <location>
            <begin position="693"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="386"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="807" mass="88886" checksum="623CF5CDABDA885D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQK5</accession>
    <name>A4RQK5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415405.1">
        <property type="nucleotide sequence ID" value="XM_001415368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQK5"/>
    <dbReference type="GeneID" id="4999696"/>
    <dbReference type="Gramene" id="ABO93697">
        <property type="protein sequence ID" value="ABO93697"/>
        <property type="gene ID" value="OSTLU_28695"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28695"/>
    <dbReference type="HOGENOM" id="CLU_2077039_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="118" mass="12920" checksum="35EF22A930A5D5D3" modified="2007-05-15" version="1">MWTACACFPCVGETLCEPGDLGYRARYLVFRCERARAIGGRAAEMAGEDVRGMVEALEDDVFACRVSAGEGAVEVEIRAGSRARVLMYALTLRTADGRGLGLELVEERRASRRETVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQM7</accession>
    <name>A4RQM7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED4</name>
        <name evidence="8" type="ORF">OSTLU_28716</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415760.1">
        <property type="nucleotide sequence ID" value="XM_001415723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQM7"/>
    <dbReference type="STRING" id="436017.A4RQM7"/>
    <dbReference type="GeneID" id="4999617"/>
    <dbReference type="Gramene" id="ABO94052">
        <property type="protein sequence ID" value="ABO94052"/>
        <property type="gene ID" value="OSTLU_28716"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28716"/>
    <dbReference type="eggNOG" id="ENOG502QQ6I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1181850_0_0_1"/>
    <dbReference type="OMA" id="PCIAVPS"/>
    <dbReference type="OrthoDB" id="515880at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019258">
        <property type="entry name" value="Mediator_Med4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13208">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13208:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10018">
        <property type="entry name" value="Med4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="205"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="25051" checksum="B6EC1DA2E8C6AC6A" modified="2007-05-15" version="1">MDVDAASSSNQALGDIALELASARNALRDALDRATNLGHVKLPPESELKVSEVLDYARRISYTTFAPAGYVPGAPLCGIMPPAPQEEHFQASRLAAFNAERRAKEKAASAAAEARQKEEARLRMVEAAAAIPPEELIERLSKWKPGEPWPDGIPPPPPGWKPGDALHFELPKREDAGVGALVKPTNAVAAAKAAPRVVPFVSLDLNPDLDDDDVASISDDFEEVSESDGGDDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQT7</accession>
    <name>A4RQT7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415791.1">
        <property type="nucleotide sequence ID" value="XM_001415754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQT7"/>
    <dbReference type="GeneID" id="4999548"/>
    <dbReference type="Gramene" id="ABO94083">
        <property type="protein sequence ID" value="ABO94083"/>
        <property type="gene ID" value="OSTLU_28776"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28776"/>
    <dbReference type="HOGENOM" id="CLU_2030625_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="122" mass="12965" checksum="165C61F557EF86C8" modified="2007-05-15" version="1">MELRMLGYDVSSGAALATRDADEHSRPLASAAPDDGDGVETSSSRVRAADAILRRLVSELREDVEASAETKDDAEDAWKPSGEDWNAPPAFLLADGAATSARGMREKYPELFAADARALGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQU4</accession>
    <name>A4RQU4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_28783</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415448.1">
        <property type="nucleotide sequence ID" value="XM_001415411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQU4"/>
    <dbReference type="STRING" id="436017.A4RQU4"/>
    <dbReference type="GeneID" id="5000061"/>
    <dbReference type="Gramene" id="ABO93740">
        <property type="protein sequence ID" value="ABO93740"/>
        <property type="gene ID" value="OSTLU_28783"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28783"/>
    <dbReference type="eggNOG" id="KOG2187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043022_0_0_1"/>
    <dbReference type="OMA" id="EINELMP"/>
    <dbReference type="OrthoDB" id="10250660at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030697">
        <property type="term" value="F:tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011869">
        <property type="entry name" value="TrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47790">
        <property type="entry name" value="TRNA/TMRNA (URACIL-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47790:SF2">
        <property type="entry name" value="TRNA_TMRNA (URACIL-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="33909" checksum="1A7FEF6EE54CEDAA" modified="2007-05-15" version="1">MWDRGAPTVMVDDFPMARRAIRDVMGRLLREASAVAALRDGLEATHFLCGVAEGKVLATLVYSTPINVDAWTLAARRLLATKFDDVSLELMGRCKGVVAKTGDDFVWEEYELGDGSVLTYKHTEGAFSNPNRTITIATMEFLRDAAKKKFSRRKMLLELYCGNANHTCALANLYERVVAVEVNPVLVDAARESLDMNSVSNVDIILSPSESVAKSLLRGKFKDAAGATIRVEDFDAVLVDPPRAGLDADTLALVSQIDHVLYVSCGPENLLANIRDGLDATHAVDDFIVLDHFPWTRHIEVAVSMRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRC6</accession>
    <name>A4RRC6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_28969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415548.1">
        <property type="nucleotide sequence ID" value="XM_001415511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRC6"/>
    <dbReference type="GeneID" id="4999576"/>
    <dbReference type="Gramene" id="ABO93840">
        <property type="protein sequence ID" value="ABO93840"/>
        <property type="gene ID" value="OSTLU_28969"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28969"/>
    <dbReference type="HOGENOM" id="CLU_505655_0_0_1"/>
    <dbReference type="OMA" id="SECTINT"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052591">
        <property type="entry name" value="CML21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23064">
        <property type="entry name" value="TROPONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="197"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="245"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="572" mass="63437" checksum="D48CBB8B235D40E1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRH2</accession>
    <name>A4RRH2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial cardiolipin hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_13850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phospholipase D family. MitoPLD/Zucchini subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415569.1">
        <property type="nucleotide sequence ID" value="XM_001415532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRH2"/>
    <dbReference type="GeneID" id="4999660"/>
    <dbReference type="Gramene" id="ABO93861">
        <property type="protein sequence ID" value="ABO93861"/>
        <property type="gene ID" value="OSTLU_13850"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13850"/>
    <dbReference type="eggNOG" id="ENOG502RYRD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_643158_0_0_1"/>
    <dbReference type="OMA" id="MYTYSHQ"/>
    <dbReference type="OrthoDB" id="5205528at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016891">
        <property type="term" value="F:RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051406">
        <property type="entry name" value="PLD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856">
        <property type="entry name" value="CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856:SF2">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672831" description="Mitochondrial cardiolipin hydrolase" evidence="3">
        <location>
            <begin position="17"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="4">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="4">
        <location>
            <begin position="354"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO93861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="440" mass="48932" checksum="7E7E899E7A6462A6" modified="2007-05-15" version="1">MRPSLWLVALGASALGAPRREYDHQNDTYAPRFREFVAAADARVGLTPFFSPDTSADASASLVREARESVDVFAPAVESWSGCGATKSGCAGCAPDRVRANEAFVLFRELLNAAHRGVRVRLLTNRFDSVRECAGAVSVLSYFAENFDVRTYTSTTFMHAKAMIVDNNVTAISSVNWSKSSYLENREAGVVARSKSVAEFAGEVFEYDWSVAEVWRMPANDGISEDEIQRMKSSEWLEPFPIPSRNISAPHYSPKKLRETWCKGAAVKVSVSPDAGAATMLEAMNASATLDIYTYQITDDFFASRLLKLADAGVIVRIVLSRAIFSDVDRKLSASLVDKMRENEKIVFRSSPRYYRYAHLKIMIVDRGREGERVVLATGNLSPSDLPLPVRPFLPLHKGGASINRDFEIVMHDANIVEQFQNLFDGDMAYTSPYRRPSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRJ3</accession>
    <name>A4RRJ3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lumenal PsbP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PSBP6</name>
        <name evidence="3" type="ORF">OSTLU_29036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415912.1">
        <property type="nucleotide sequence ID" value="XM_001415875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRJ3"/>
    <dbReference type="GeneID" id="4999399"/>
    <dbReference type="Gramene" id="ABO94204">
        <property type="protein sequence ID" value="ABO94204"/>
        <property type="gene ID" value="OSTLU_29036"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29036"/>
    <dbReference type="HOGENOM" id="CLU_084049_0_0_1"/>
    <dbReference type="OMA" id="KVQVRPY"/>
    <dbReference type="OrthoDB" id="496472at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF16">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="2">
        <location>
            <begin position="112"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="289" mass="31053" checksum="EDEB9715EAAB6364" modified="2007-05-15" version="1">MATTTTAAFARAARAAARADARATGRDARRAARGARATRRANDGEVEVEVGTGDGDGARGARATTRRRALAATVFVGAAASGVGASRAEDEITAGAREALALAPTTLDDVELEPYVDLDNGYAFLSPKGWVKDLPNGIAEIEIHPVSEYGGRRFKVQVRPYGKKTKSLRVDELDEPEYANPRAYAEDVARKYAPLEGEGETNRGQAVSKVLSSRMSDDGRYYYFEYSTESMLPLHFWGVLALGPGPVGSARKLGRKDIITMTCQMPEDKGPEAAALLEHLVSTFKVLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRR4</accession>
    <name>A4RRR4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_13922</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415946.1">
        <property type="nucleotide sequence ID" value="XM_001415909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRR4"/>
    <dbReference type="STRING" id="436017.A4RRR4"/>
    <dbReference type="GeneID" id="4999598"/>
    <dbReference type="Gramene" id="ABO94238">
        <property type="protein sequence ID" value="ABO94238"/>
        <property type="gene ID" value="OSTLU_13922"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13922"/>
    <dbReference type="eggNOG" id="KOG4213">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_817211_0_0_1"/>
    <dbReference type="OMA" id="HHRLNDA"/>
    <dbReference type="OrthoDB" id="439993at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12291">
        <property type="entry name" value="RRM1_La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="5">
        <location>
            <begin position="43"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="171"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="257"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="38140" checksum="119074067DF07852" modified="2007-05-15" version="1">MTTDATDAVASDAPSDAPRDAPRASTGDDDARARREDDATGAADFDDATRDRVRAQIEFYLGDSNLPRDAFLLDEVSRAVREGHEGGVPIALIASFSRMRDFLAAYGGKDEAKNVERVARALEGSDVVEACADGTRVRRKSMLVNGETPDLATDDGVTAYRSAMVEELDKRFVFASPFAKDATIEALLAYFKTVGNARSIRLRRHTTSKDFRGSIFVEFATEEEAKAIAERADLEYKGAKLTLMMKAAYMEQKKQEQLEKKAKAREEAIARGEDPDAQPPTTHEPVFVGKVDERGRGGRGGRGGGRGGRGGRGRGDGGGGRGGPDRGGARFGGGGGDSANKPKEDGDKPRFGRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSY3</accession>
    <name>A4RSY3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 18">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="12">IMP dehydrogenase</shortName>
            <shortName evidence="12">IMPD</shortName>
            <shortName evidence="12">IMPDH</shortName>
            <ecNumber evidence="12 18">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">IpdH</name>
        <name evidence="20" type="ORF">OSTLU_119530</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12 18">
            <text>IMP + NAD(+) + H2O = XMP + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 18">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12 17">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="12 18"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416409.1">
        <property type="nucleotide sequence ID" value="XM_001416372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSY3"/>
    <dbReference type="STRING" id="436017.A4RSY3"/>
    <dbReference type="GeneID" id="5000498"/>
    <dbReference type="Gramene" id="ABO94702">
        <property type="protein sequence ID" value="ABO94702"/>
        <property type="gene ID" value="OSTLU_119530"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119530"/>
    <dbReference type="eggNOG" id="KOG2550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022552_2_1_1"/>
    <dbReference type="OMA" id="MGYCGAK"/>
    <dbReference type="OrthoDB" id="416622at2759"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04601">
        <property type="entry name" value="CBS_pair_IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000086">
        <property type="entry name" value="IMP dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01240">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0129">CBS domain</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 12 18" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 12 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 14" id="KW-0520">NAD</keyword>
    <keyword evidence="7 12 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 12 15" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 12 18" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="19">
        <location>
            <begin position="166"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="12 13">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12 13">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <begin position="264"/>
            <end position="266"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <begin position="314"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="354"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="377"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="401"/>
            <end position="405"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABO94702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="502" mass="53830" checksum="6D3337E6138F9B06" modified="2007-05-15" version="1">MASLDGFPGEALFNQGFCYTYDDVIFHPGFIDFAADQVDLSTRVSRNVSIRTPMVSSPMDTVTESDMAIAMAEAGGMGFLHYNMAMESQLEHAKIVKSHRPGYVANPAVLRPSATLRDLDELRAARGFSSVCISESGTCGSALLGLVTTRDAELVRDRNTLLSEVMTSVDDLVLGSTEKSAQENEQILLESKRGKLPIVDAKRYLIGLLTRATIKDRLNRPPSGVPSIDKHGRLLCGAAIGTRDADRVRAKYLADAGVDAIILDSSQGDSIYQLEMIKYLKNELPHVDVIAGNVVTQNQARRLLEVGADGLRVGMGSGSICTTQEVCAVGRGQATAVYKVGQIAKEFNVPIIADGGIQNSGHIVKALALGASVAMCGSMFSGTTEAPGQYFYQDGVRVKKYRGMGSLDAMKKGSDSRYLSESGHLKIAQGVSGTVRDKGSVKTMIPYLVHGVKQGFQDLGADSLTKAHQILASGTMTMEARTGAAQREGGIHDMHSYTKVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSZ9</accession>
    <name>A4RSZ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3/1,6-mannosyltransferase ALG2</fullName>
            <ecNumber evidence="10">2.4.1.132</ecNumber>
            <ecNumber evidence="10">2.4.1.257</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Alg2</name>
        <name evidence="14" type="ORF">OSTLU_119517</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>a beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19511"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58472"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="EC" id="2.4.1.132"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8 10">
            <dbReference type="Rhea" id="RHEA:29516"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29519"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="EC" id="2.4.1.257"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9 10">
            <dbReference type="Rhea" id="RHEA:29520"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.132" evidence="10"/>
    <dbReference type="EC" id="2.4.1.257" evidence="10"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416402.1">
        <property type="nucleotide sequence ID" value="XM_001416365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSZ9"/>
    <dbReference type="STRING" id="436017.A4RSZ9"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="GeneID" id="5000192"/>
    <dbReference type="Gramene" id="ABO94695">
        <property type="protein sequence ID" value="ABO94695"/>
        <property type="gene ID" value="OSTLU_119517"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119517"/>
    <dbReference type="eggNOG" id="KOG0853">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030619_1_0_1"/>
    <dbReference type="OMA" id="AMYMKCP"/>
    <dbReference type="OrthoDB" id="448893at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004378">
        <property type="term" value="F:GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102704">
        <property type="term" value="F:GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03805">
        <property type="entry name" value="GT4_ALG2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027054">
        <property type="entry name" value="ALG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918">
        <property type="entry name" value="ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918:SF1">
        <property type="entry name" value="ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 10 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="13">
        <location>
            <begin position="38"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="12">
        <location>
            <begin position="235"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="480" mass="54891" checksum="651E5BC8289F21D9" modified="2007-05-15" version="1">MFATKDLSKECRAKSSAHTDGTSKPLRINIIHPDLGLGGAERLILDFARACSTAGHEIKLYTAFHDENRCFEDTVNTEGKRVDWIQVYNSLVPRNFAGRFHAICANLRCLCVVFFALWRDCGKVDVWILDQVPIPIFVLKIFAQRTIFYCHFPDCLLAPHNTTLQRLYRTPIDYVEEHCTGMADCIVVNSYFTAEVFSRTFKRLYRKGISPEVVYPTASLTELEFTHDVDATFRTFPGKSLIFQERKIFLSINRFDSNKNLRLAILAFHKFIQQNRNDATYMLILAGGFDSRLQDNVQVLRELRRLKDDLELSDSVLFLPSINNHQKQVLLHHSLCVLYTPNEEHFGIVPLEAMQYHKPVVACNSGGPKETVIHGVTGFLCENTPESFACAMSKLARVSGLAERMGNAAQLNFGQKFDVVAFRRRVREVLSNTAESNCEPQIRSSVPLFWYLWIFLSSALLLAIFICVSVYHHSVHFFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTT5</accession>
    <name>A4RTT5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBCC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416840.1">
        <property type="nucleotide sequence ID" value="XM_001416803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTT5"/>
    <dbReference type="GeneID" id="5000993"/>
    <dbReference type="Gramene" id="ABO95133">
        <property type="protein sequence ID" value="ABO95133"/>
        <property type="gene ID" value="OSTLU_30377"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30377"/>
    <dbReference type="HOGENOM" id="CLU_1698445_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="155" mass="16691" checksum="822A95EDBFFC4BFC" modified="2007-05-15" version="1">MERSAYVTKFFAQGCEDCVFVICCAVKEVNVLDCKRCVFVFGPTTDSTTARDCLSCDIATCATVGAFTLEDCVNVRAFVKTYGNGSRARAERCSTTAFGTCDLEYDELEEQMASCGFVDANGDLLASTMTVSSETSTLESTAREVVGHALERVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTX9</accession>
    <name>A4RTX9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycerophosphocholine acyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_34546</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416574.1">
        <property type="nucleotide sequence ID" value="XM_001416537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTX9"/>
    <dbReference type="GeneID" id="5000583"/>
    <dbReference type="Gramene" id="ABO94867">
        <property type="protein sequence ID" value="ABO94867"/>
        <property type="gene ID" value="OSTLU_34546"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34546"/>
    <dbReference type="eggNOG" id="KOG2895">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018994_1_1_1"/>
    <dbReference type="OMA" id="WKRRVPT"/>
    <dbReference type="OrthoDB" id="406287at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021261">
        <property type="entry name" value="GPCAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201">
        <property type="entry name" value="OS01G0585100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10998">
        <property type="entry name" value="DUF2838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="345" mass="39862" checksum="5E719A1102305F47" modified="2007-05-15" version="1">MRRAVTGNADTRVRDYVKIPRVIRQIDKVSFCAGVYGLMMTEYIATRAPEKFWLFYAVAMPGVFLARAVYYRMIRWQYFLYDFCYFANASAMMFLWRWKKSATVFRCIFAFANGPVLLAIPLWRNSLVFHSVDKVSSIFVHAMPCLMTWCGRWYGFGNDVNRLSVRELGADVSVLTGCLDLMVYPMFAYLFWQALYLAKTELIDRVKLVSDPALMTSLRWLASDRNSSANKYALKMMRGIGLFGADEFFDAESIKTKFVFVMLQLGYTIVTFIPIPLCYSNYYAHTALMWAAFGSSVYNGAVYYIDVFSRRYVERLAMAEELERDSQSPGLSESEIDRLMMTPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU01</accession>
    <name>A4RU01_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_24185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO94877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416547.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABO94877"/>
        <property type="gene ID" value="OSTLU_24185"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24185"/>
    <dbReference type="HOGENOM" id="CLU_666311_0_0_1"/>
    <dbReference type="OMA" id="QVYYWNT"/>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
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        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAP" evidence="5">
        <location>
            <begin position="4"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="380"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
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        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="42752" checksum="77020769754EFBC9" modified="2007-05-15" version="1">MAGCAKMTVAVLKEELKKRGLDATGLKAALVARLEEAMAGEDDGAAAEAAAPEEEEAKEEPKEEAGEEEDVRAKAEEMAEKAMAEHAASEKKRERSPEQDDAPPEAKSAKSDGEHAAAPSSAQGGLTKDGQNLATYEMPDGQVRKDVPTQGNEGRIIGRGGSKIRELQDMFRTRITMNRPAGLAEVVGMLDHVNDCCDEITRIVEDGNVREAAERAGQPVPGGAYSSYGGGGFGGGGGGFGGGGFGGGGGGGGGGPFSGHMERVPCEGQEGRIIGRGGENIRRVESQTGTRIKMNRVDNVAEVYGTPAQCTEAVRMIQEYIHTAPNRGGGGFGGGGFGQQGGYGGGYQQQSFGQQAGYGGGYQQQAGYGQPAYGAPAGGAPLPHGWEEVNPGNGGPVYYWDTVSNTTTYTRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU83</accession>
    <name>A4RU83_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416627.1">
        <property type="nucleotide sequence ID" value="XM_001416590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU83"/>
    <dbReference type="STRING" id="436017.A4RU83"/>
    <dbReference type="GeneID" id="5000784"/>
    <dbReference type="Gramene" id="ABO94920">
        <property type="protein sequence ID" value="ABO94920"/>
        <property type="gene ID" value="OSTLU_30530"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30530"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_8_2_1"/>
    <dbReference type="OMA" id="IRTCIDF"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF34">
        <property type="entry name" value="ABC1 ATYPICAL KINASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="1">
        <location>
            <begin position="125"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="1">
        <location>
            <begin position="371"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="551" mass="62164" checksum="2D9E341363A02146" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUD9</accession>
    <name>A4RUD9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_14601</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416942.1">
        <property type="nucleotide sequence ID" value="XM_001416905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUD9"/>
    <dbReference type="STRING" id="436017.A4RUD9"/>
    <dbReference type="GeneID" id="5000997"/>
    <dbReference type="Gramene" id="ABO95235">
        <property type="protein sequence ID" value="ABO95235"/>
        <property type="gene ID" value="OSTLU_14601"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14601"/>
    <dbReference type="eggNOG" id="KOG1175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_6_1"/>
    <dbReference type="OMA" id="AHERYEN"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="59"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="525"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="651" mass="72154" checksum="47A9F8731B4D3002" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUE2</accession>
    <name>A4RUE2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">MC family transporter: oxaloacetate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_34271</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416656.1">
        <property type="nucleotide sequence ID" value="XM_001416619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUE2"/>
    <dbReference type="STRING" id="436017.A4RUE2"/>
    <dbReference type="GeneID" id="5000646"/>
    <dbReference type="Gramene" id="ABO94949">
        <property type="protein sequence ID" value="ABO94949"/>
        <property type="gene ID" value="OSTLU_34271"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34271"/>
    <dbReference type="eggNOG" id="KOG0755">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_14_3_1"/>
    <dbReference type="OMA" id="GFYDPMR"/>
    <dbReference type="OrthoDB" id="496483at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="92"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="188"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="267" mass="28918" checksum="01AC5A0BE02A1230" modified="2007-05-15" version="1" fragment="single">MPNSALASCLAVLATNPMDRAKTIMQLPGVGASWGKNMREVTMNMVKKEGALRGLYRGLPVAMVRESSKNVFRIGLFLPVLKVIHTDDDNPAPAWKRFMAGCLSGGIGAVSSNPFDLIKTRMQVPAAMCEYENGMVALKKICAKEGWKTLYKGVGASVMRDMLGSSVNLTVQSIASEALVRNMILSPGSPVLGALSGVLSAAASVAVMQPIDTSRAYVYLKPHIHKDTIRAFRYIVLREGPLALYKGSRAHFFRTAPHYAAMFALLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUX8</accession>
    <name>A4RUX8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lhcp2.2</name>
        <name evidence="11" type="synonym">lhcp2.1</name>
        <name evidence="10" type="synonym">lhcp2.3</name>
        <name evidence="8" type="synonym">lhcp2.4</name>
        <name evidence="11" type="ORF">OSTLU_27706</name>
        <name evidence="9" type="ORF">OSTLU_30780</name>
        <name evidence="8" type="ORF">OSTLU_30781</name>
        <name evidence="10" type="ORF">OSTLU_50137</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416747.1">
        <property type="nucleotide sequence ID" value="XM_001416710.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417039.1">
        <property type="nucleotide sequence ID" value="XM_001417002.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418704.1">
        <property type="nucleotide sequence ID" value="XM_001418667.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421688.1">
        <property type="nucleotide sequence ID" value="XM_001421651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUX8"/>
    <dbReference type="STRING" id="436017.A4RUX8"/>
    <dbReference type="GeneID" id="5000601"/>
    <dbReference type="GeneID" id="5000804"/>
    <dbReference type="GeneID" id="5002722"/>
    <dbReference type="GeneID" id="5005661"/>
    <dbReference type="Gramene" id="ABO95040">
        <property type="protein sequence ID" value="ABO95040"/>
        <property type="gene ID" value="OSTLU_30781"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO95332">
        <property type="protein sequence ID" value="ABO95332"/>
        <property type="gene ID" value="OSTLU_30780"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO96997">
        <property type="protein sequence ID" value="ABO96997"/>
        <property type="gene ID" value="OSTLU_50137"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99981">
        <property type="protein sequence ID" value="ABO99981"/>
        <property type="gene ID" value="OSTLU_27706"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27706"/>
    <dbReference type="KEGG" id="olu:OSTLU_30780"/>
    <dbReference type="KEGG" id="olu:OSTLU_30781"/>
    <dbReference type="KEGG" id="olu:OSTLU_50137"/>
    <dbReference type="HOGENOM" id="CLU_1201257_0_0_1"/>
    <dbReference type="OMA" id="AYRTGIS"/>
    <dbReference type="OrthoDB" id="494132at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="233" mass="24612" checksum="9D1D7FD548021651" modified="2007-05-15" version="1">MSALLASSFVGRVAAFKATKIQAKSVSTTVKADIYPEFGTYPGGGESPIIPFGDEKNAEREVIHGRWAMLGVTGAWAAENGTGIPWFTAGTLCTPDDCTAVADKFPGAVAPLAPEGSGYPSFWNVLIIEIVLVGAAEAYRTGISDSPFDDGLTVGDVNPGGRFDPLGLAESGDLEELKIKELKHCRLSMFAWLGCIFQALATQEGPIANWQSHVADPVHSNVLTNAAKGFGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVB0</accession>
    <name>A4RVB0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_30910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417108.1">
        <property type="nucleotide sequence ID" value="XM_001417071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVB0"/>
    <dbReference type="STRING" id="436017.A4RVB0"/>
    <dbReference type="GeneID" id="5000912"/>
    <dbReference type="Gramene" id="ABO95401">
        <property type="protein sequence ID" value="ABO95401"/>
        <property type="gene ID" value="OSTLU_30910"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30910"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039242_0_0_1"/>
    <dbReference type="OMA" id="NGFRWPF"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072593">
        <property type="term" value="P:reactive oxygen species metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000019">
        <property type="entry name" value="probable aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521:SF7">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 12A1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="82"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="521" mass="56519" checksum="2D5D68914F77E186" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVG1</accession>
    <name>A4RVG1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_92549</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417129.1">
        <property type="nucleotide sequence ID" value="XM_001417092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVG1"/>
    <dbReference type="GeneID" id="5001219"/>
    <dbReference type="Gramene" id="ABO95422">
        <property type="protein sequence ID" value="ABO95422"/>
        <property type="gene ID" value="OSTLU_92549"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92549"/>
    <dbReference type="HOGENOM" id="CLU_977921_0_0_1"/>
    <dbReference type="OMA" id="CGFMNPA"/>
    <dbReference type="OrthoDB" id="498716at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="285" mass="29305" checksum="5BAF43B3E4B4B6EB" modified="2007-05-15" version="1">MPRPRASQTPSFALEFASSFVVCAALATLDVQATLARKYLGPILERVGARALADDDAAVTLALLFVNLAIVFSPSYQALTRGATNNPTAYALKGMLGDTGAARACANACAAVLAHVCALKAVMVVMRTHPEYLPGKGAIAPIVPTGTTASAAAAETAVVAANFLFFGLAERAFAAALIPTLVSGFYVMTMMIEGCRYSCGYMNPSTVIASHALAGDLKSREAFEAIAPYVIGGIAGSVIVAIAAKVLVPEPKSAKRARAQSKAVVRSISKARAGGAATRKGAKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVH9</accession>
    <name>A4RVH9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_30981</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417423.1">
        <property type="nucleotide sequence ID" value="XM_001417386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVH9"/>
    <dbReference type="STRING" id="436017.A4RVH9"/>
    <dbReference type="GeneID" id="5001144"/>
    <dbReference type="Gramene" id="ABO95716">
        <property type="protein sequence ID" value="ABO95716"/>
        <property type="gene ID" value="OSTLU_30981"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30981"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036752_0_0_1"/>
    <dbReference type="OMA" id="CTEVYDE"/>
    <dbReference type="OrthoDB" id="42736at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="247"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="282"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="353"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="48509" checksum="16483E105F72346B" modified="2007-05-15" version="1">MESIDAPAQGERIAWDVVASAVNPEGGKFKFTTSTLNFAIKELGERGSFDRAHALYLWMSRKQGRYAPNEFTYVSLASAAKTLTQTRTVQNLWQRGIAENDESLICNEIASAVIAALNRVSDWSGAYQVFRDMGDKGKPRNLYTYTAVLTALRDEAKPDEALAVLNEMAREPGVQPTSLAFSLTLTAFDNCRRWIEGNAVAKRIKKYDVRPDATLMHAIITMAGRAGDMAHANEVFDAMRNSTMIVTTYTFNALLGGYARYGDWEGCTEVYDEMKRSKIQPDSYTFTQLISAAERSGEYIAADGVWTEMLRNRIIPHTVMCGAYIHCLGCQGRDLEAEAVMEKMRNYWDVPRNAAVYNALIGAHVRSGEVTRGLSVLDDMQRIDGLMPTEITFAVLIRACQESALHKRAEGLEGMRASLANAGQLIQDLSGASTSTAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVL1</accession>
    <name>A4RVL1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC(ATP-binding) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_49454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417437.1">
        <property type="nucleotide sequence ID" value="XM_001417400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVL1"/>
    <dbReference type="SMR" id="A4RVL1"/>
    <dbReference type="STRING" id="436017.A4RVL1"/>
    <dbReference type="GeneID" id="5001380"/>
    <dbReference type="Gramene" id="ABO95730">
        <property type="protein sequence ID" value="ABO95730"/>
        <property type="gene ID" value="OSTLU_49454"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49454"/>
    <dbReference type="eggNOG" id="KOG0927">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_1"/>
    <dbReference type="OMA" id="QWTPVGD"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000309">
        <property type="entry name" value="ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051309">
        <property type="entry name" value="ABCF_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42855">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42855:SF1">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="56"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="380"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="604"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="640"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00061344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="649" mass="72906" checksum="3643B4E6F815081D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVM8</accession>
    <name>A4RVM8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417170.1">
        <property type="nucleotide sequence ID" value="XM_001417133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVM8"/>
    <dbReference type="GeneID" id="5001604"/>
    <dbReference type="Gramene" id="ABO95463">
        <property type="protein sequence ID" value="ABO95463"/>
        <property type="gene ID" value="OSTLU_31032"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31032"/>
    <dbReference type="HOGENOM" id="CLU_1017038_0_0_1"/>
    <dbReference type="OMA" id="PPIELDC"/>
    <dbReference type="OrthoDB" id="497422at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF113">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="68"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="198"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="274" mass="30517" checksum="6A3CAEF8F2D6187B" modified="2007-05-15" version="1">MKASLLRPLTLTARLRAVHRVKPRLNTARSLVTRADATDQSGSGAFVRGQAQFSKFYPSEARDFTFSRHVMLAVDGTHASEDAARWVIQNVVRSGDLLHLIHVAVPESFGVYYLGAPGTEIAGSELDWERKDEFWASCIRRTERMLDGTVTHIIGEDADAGEEMTPFRPPIELDCILDQTWYASLDIRNAYLSTFDREPVGEVLLNKAKESNAEILVVIKHHKSWVQKIFSGSVSEYLIDKSEIPILVFPAAMPASSEDLILGDEDDQSSKGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVP7</accession>
    <name>A4RVP7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosomal protein S3, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPS3</name>
        <name evidence="7" type="ORF">OSTLU_49305</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417450.1">
        <property type="nucleotide sequence ID" value="XM_001417413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVP7"/>
    <dbReference type="STRING" id="436017.A4RVP7"/>
    <dbReference type="GeneID" id="5001215"/>
    <dbReference type="Gramene" id="ABO95743">
        <property type="protein sequence ID" value="ABO95743"/>
        <property type="gene ID" value="OSTLU_49305"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49305"/>
    <dbReference type="eggNOG" id="KOG3181">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058591_2_1_1"/>
    <dbReference type="OMA" id="THPKMAV"/>
    <dbReference type="OrthoDB" id="10248446at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.32:FF:000004">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000006">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003219">
        <property type="entry name" value="PRK04191.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF37">
        <property type="entry name" value="RIBOSOMAL PROTEIN S3, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="6">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="231" mass="25812" checksum="482461742BE809D0" modified="2007-05-15" version="1">MVATAISKKRKFVADGVFFAELNEMLVRELAEDGYSGVEVRQTPMRTEIIIRATRTANVLGEKGRRIRELTTLVQRRFQMAEGSVELYAERVNNRGLCAIAQCESLRYKLLGGLAVRRACYGVLRYIMEAGAKGAEVVVSGKLRGQRAKAMKFKDGYMISSGNPVREYIVSCTRHALLRQGTIGMRVKIMLDHDPKGRNGPSTPIPDTVVIHTPKDDEDMAKPYVGKEMEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVR7</accession>
    <name>A4RVR7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Splicing factor Cactin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_36934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417459.1">
        <property type="nucleotide sequence ID" value="XM_001417422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVR7"/>
    <dbReference type="STRING" id="436017.A4RVR7"/>
    <dbReference type="GeneID" id="5001208"/>
    <dbReference type="Gramene" id="ABO95752">
        <property type="protein sequence ID" value="ABO95752"/>
        <property type="gene ID" value="OSTLU_36934"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36934"/>
    <dbReference type="eggNOG" id="KOG2370">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104334_1_0_1"/>
    <dbReference type="OMA" id="APEYYLE"/>
    <dbReference type="OrthoDB" id="265955at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019134">
        <property type="entry name" value="Cactin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737">
        <property type="entry name" value="POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737:SF4">
        <property type="entry name" value="SPLICING FACTOR CACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09732">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Splicing factor Cactin C-terminal" evidence="1">
        <location>
            <begin position="24"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="149" mass="17678" checksum="AD0FC38BFF328069" modified="2007-05-15" version="1">MGATEDGDANFSAEVALESQAYWWHDKYRPRKPKYFNRVHTGYSWNKYNQTHYDSSNPPPKIVQGYKFNIFYPDLIDTTKAPSYKIEPDGSPNAETCLLKITAGPPYEDIAFKIVNKEWEYSHKRGFRCTFERGIFHLYVNFKRSRYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWF1</accession>
    <name>A4RWF1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_36839</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417566.1">
        <property type="nucleotide sequence ID" value="XM_001417529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWF1"/>
    <dbReference type="STRING" id="436017.A4RWF1"/>
    <dbReference type="GeneID" id="5001236"/>
    <dbReference type="Gramene" id="ABO95859">
        <property type="protein sequence ID" value="ABO95859"/>
        <property type="gene ID" value="OSTLU_36839"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36839"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_2_0_1"/>
    <dbReference type="OMA" id="VDPRSYM"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051169">
        <property type="entry name" value="NADH-Q_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42913:SF4">
        <property type="entry name" value="ALTERNATIVE NAD(P)H-UBIQUINONE OXIDOREDUCTASE C1, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42913">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="55"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="493" mass="53008" checksum="2434E3F433637817" modified="2007-05-15" version="1">MPPSIARTAFDASCSTRSTRRAPSRARSLRARPDKRCVTSPRATAEPSSSSSPRRVVVLGGGFGGLYTALRLDSLEWAGETRPEITVVDRAEAFVFKPLLYELVNETLEPWEVAPTFEELLKPTKVTHVKGEVVSFEPEDRGTMRDGTPYSATGGSITLGDGTTLAYDYLVLALGTSTSDGGVAGARECAVALNTAEDAVRIAGVLGELERAGRDARVAVIGGGLSGVELASVIAERLNGKSTNGVVDVITPNKRVMATAPPGQREAALRVLEKARVNVVGGRVMRLDKVANDEETVSTASKITLADDDGAEGVETYDLVCWTVGQRAETPSDWPVATTPARKIKTDATLRVNGHSRIYAVGDASSSSAEVMNADWDHLPSTAQVAFQQADYAAWNIWASMNGRTELPFRYQHLGDMMVLGSLDAAVAFPVGDITLEGPAAAALRRLAYLYRMPTNEHRLKLGSKWIQDGIETFQKDPVGFLEDIRKSIPFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWM2</accession>
    <name>A4RWM2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CDC20/Fizzy WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_31385</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417356.1">
        <property type="nucleotide sequence ID" value="XM_001417319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWM2"/>
    <dbReference type="STRING" id="436017.A4RWM2"/>
    <dbReference type="GeneID" id="5001543"/>
    <dbReference type="Gramene" id="ABO95649">
        <property type="protein sequence ID" value="ABO95649"/>
        <property type="gene ID" value="OSTLU_31385"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31385"/>
    <dbReference type="eggNOG" id="KOG0305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014831_6_1_1"/>
    <dbReference type="OMA" id="RQVRTMN"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="10">
        <location>
            <begin position="139"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="229"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="270"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="403"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="462" mass="50693" checksum="85D5B2CC4F44FA5D" modified="2007-05-15" version="1">MLSPTRRRATVESTTSFEHCRAGTPTGRAQVDRFIPSRSALDLDVAHYNLSREGGESEVDDAVKEIKSPAKEAYKKSLADNFHVDNGSDSAKILAFKSKAPAPPSGLENSARGVYTNNSAGVKAKKTFRQIPSAPERILDAPELIDDYYLNLIDWGSSNQVAVALGCTVYMWNADTGAINQLCQTNPDDEDDYITSVNWGADGKHIAVGTNSAEVQIWDAAQCKKVRTLRGHAARVGAVSWNGSQLATGSRDNNIMIHDVRIREHCTSTLQVHQQEVCGLKWSPSGNQLASGGNDNLLHIFDASSIGNQQALHRLDAHQAAVKALAWCPFQSNLLASGGGTADRCIKFWNTNTGAMLNSVDTHSQVCSLQWNTHERELLSSHGYSQNQLCLWKYPTMTKMAELTGHQARVLHMAQSPDGTTVVSAAADETLRFWKCFDNASEKTKKVRDSNDSSVLRRFNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWR5</accession>
    <name>A4RWR5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_31430</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417376.1">
        <property type="nucleotide sequence ID" value="XM_001417339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWR5"/>
    <dbReference type="STRING" id="436017.A4RWR5"/>
    <dbReference type="GeneID" id="5001664"/>
    <dbReference type="Gramene" id="ABO95669">
        <property type="protein sequence ID" value="ABO95669"/>
        <property type="gene ID" value="OSTLU_31430"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31430"/>
    <dbReference type="HOGENOM" id="CLU_206164_0_0_1"/>
    <dbReference type="OMA" id="AYGKPRA"/>
    <dbReference type="OrthoDB" id="1920692at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="65" mass="6726" checksum="55484C6771C74768" modified="2007-05-15" version="1">MPVESVPPFAIIVGAITAMGGLQYLTHGAAYGKPRAIGQDAFDRLVAARDERVKTAAASGRGAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX18</accession>
    <name>A4RX18_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_3230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417919.1">
        <property type="nucleotide sequence ID" value="XM_001417882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX18"/>
    <dbReference type="STRING" id="436017.A4RX18"/>
    <dbReference type="GeneID" id="5001677"/>
    <dbReference type="Gramene" id="ABO96212">
        <property type="protein sequence ID" value="ABO96212"/>
        <property type="gene ID" value="OSTLU_3230"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3230"/>
    <dbReference type="eggNOG" id="KOG0704">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044516_1_0_1"/>
    <dbReference type="OMA" id="GGWAGWD"/>
    <dbReference type="OrthoDB" id="983479at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000014">
        <property type="entry name" value="ADP-ribosylation factor GTPase-activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044519">
        <property type="entry name" value="ARF_GAP_AGD6/7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47021">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47021:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="313" mass="33095" checksum="77423512E4129AB3" modified="2007-05-15" version="1" fragment="single">LRALQRADGNAQCADCETKNPQWASVSHGAFVCLECSGVHRSLGVHVSFVRSASMDSWSAAQLAKMRAGGNDALNAFLERHGVPRRTAIKEKYNSDAARVFREKVAAEANGEAWTAPTRVERGARREDAETRRDAEGRGRGHGGDGGGWNDGGIDDGRGRGRAGARPGEEYTASEYAASAAQKDAFFARQQALNANKPEGLHPSQGGKYVGFGSGGGGAPRQEDEFEAIIGQVSNVTSKLGQFTMSAANRAAQATSSIVSNISDGDYDQLQHRASQTATVAANKASELAKQGWGFFKAVSGQAMKSIETLTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX94</accession>
    <name>A4RX94_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L35, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL35</name>
        <name evidence="5" type="ORF">OSTLU_31613</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417713.1">
        <property type="nucleotide sequence ID" value="XM_001417676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX94"/>
    <dbReference type="STRING" id="436017.A4RX94"/>
    <dbReference type="GeneID" id="5001697"/>
    <dbReference type="Gramene" id="ABO96006">
        <property type="protein sequence ID" value="ABO96006"/>
        <property type="gene ID" value="OSTLU_31613"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31613"/>
    <dbReference type="eggNOG" id="KOG3436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110381_1_1_1"/>
    <dbReference type="OMA" id="VMNQKAR"/>
    <dbReference type="OrthoDB" id="528635at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00427">
        <property type="entry name" value="Ribosomal_L29_HIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.310:FF:000002">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3450:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="13981" checksum="740371B7C6C6E6AD" modified="2007-05-15" version="1">MVHLRCHELRERSKHDLKQQLEQLKTELAALRVAKVTGGAPGKLSKIKQVRLAIAQTLTVMRHKQLNSLREAYAGAKYTPLDLRQKKTRAIRRALTKSEKGAKTVRQAKKDAAFPKRKYALKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX99</accession>
    <name>A4RX99_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PCIF1 WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_38638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417960.1">
        <property type="nucleotide sequence ID" value="XM_001417923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX99"/>
    <dbReference type="GeneID" id="5001699"/>
    <dbReference type="Gramene" id="ABO96253">
        <property type="protein sequence ID" value="ABO96253"/>
        <property type="gene ID" value="OSTLU_38638"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38638"/>
    <dbReference type="eggNOG" id="ENOG502QVT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091884_0_0_1"/>
    <dbReference type="OMA" id="THECYAS"/>
    <dbReference type="OrthoDB" id="567664at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016422">
        <property type="term" value="F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099122">
        <property type="term" value="F:RNA polymerase II C-terminal domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039881">
        <property type="entry name" value="PCIF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022035">
        <property type="entry name" value="PCIF1_WW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727:SF0">
        <property type="entry name" value="MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727">
        <property type="entry name" value="PHOSPHORYLATED CTD INTERACTING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12237">
        <property type="entry name" value="PCIF1_WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCIF1 WW" evidence="1">
        <location>
            <begin position="40"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="265" mass="29951" checksum="69411E4D94948954" modified="2007-05-15" version="1">MRNEFRGPATSVSKEERADGVVSLRVGKTEVRLNGDHFEKLKTLYANASSKEFVENDFLFDAFAMVCRYDAAAGGQFRFSGGSQASLHGQVFDVLRDCFKVECELFASPLNCRWPMYYSKYGDVDKPFGSLGDFRACKPSGGAFEANPPFDEDVVARMAEHLFECLDAASSALTFVVVTPHWPNRPCWEKMRRSKFCSRAEVISVREHGYYEGAQHRKKSRYRLATSDTSVLFLQNESAVESNPVTDEKISLLREAFRAKRDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXF4</accession>
    <name>A4RXF4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417741.1">
        <property type="nucleotide sequence ID" value="XM_001417704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXF4"/>
    <dbReference type="GeneID" id="5001742"/>
    <dbReference type="Gramene" id="ABO96034">
        <property type="protein sequence ID" value="ABO96034"/>
        <property type="gene ID" value="OSTLU_15401"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15401"/>
    <dbReference type="HOGENOM" id="CLU_266621_0_0_1"/>
    <dbReference type="OMA" id="RAWAHAK"/>
    <dbReference type="OrthoDB" id="10255522at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF80">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="485"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="667"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="754"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1242" mass="135672" checksum="0016E5796950678E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXN8</accession>
    <name>A4RXN8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_31760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418025.1">
        <property type="nucleotide sequence ID" value="XM_001417988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXN8"/>
    <dbReference type="STRING" id="436017.A4RXN8"/>
    <dbReference type="GeneID" id="5002103"/>
    <dbReference type="Gramene" id="ABO96318">
        <property type="protein sequence ID" value="ABO96318"/>
        <property type="gene ID" value="OSTLU_31760"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31760"/>
    <dbReference type="eggNOG" id="KOG0557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_2_1"/>
    <dbReference type="OMA" id="ATIEWEA"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000003">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="8">
        <location>
            <begin position="128"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="421" mass="44738" checksum="349117DFEAAE02AC" modified="2007-05-15" version="1">MPALSPTMERGGIARWHRAIGDEIKAGDAIADVETDKATMAMEATDDGYLAAILVPEGATDVEVGTPVCVMCEEASAVAAFKDYKATETVTTEPAKSAVETAVTMPVVRASTRATARMSARASGERVFASPLARRLAEERGVRLETVSGSGPNGRVIAEDVLTARASSASEAVTHTVVAEHPLSKFFPDFEDVSVSAIKRVTAERLTESKQQLPHFYLTVDVRLDNMMGIRETLNKQLADDKAAEGAKISVNDFIVKASAKALLAVPDVNASWLGDKIRKYKKADISVAVQTERGLMVPIVRSACCLGLKSISAEVKSLAGRARSGSLTPQDMTGGTFTISNLGMFGVKNFAAIVNPPQAAILAVGGARKEVVKNAEGGYEEVLVMSATLSCDHRVVDGAVGAQWLQSFKCYLEDPMTMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY26</accession>
    <name>A4RY26_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_87378</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417855.1">
        <property type="nucleotide sequence ID" value="XM_001417818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY26"/>
    <dbReference type="STRING" id="436017.A4RY26"/>
    <dbReference type="GeneID" id="5002010"/>
    <dbReference type="Gramene" id="ABO96148">
        <property type="protein sequence ID" value="ABO96148"/>
        <property type="gene ID" value="OSTLU_87378"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87378"/>
    <dbReference type="eggNOG" id="ENOG502SCTP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_444547_0_0_1"/>
    <dbReference type="OMA" id="REYDDTK"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058582">
        <property type="entry name" value="KH_NusA_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="TF_NusA_bacterial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="TF_NusA_KH_1st"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR NUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648:SF0">
        <property type="entry name" value="TRANSCRIPTION TERMINATION_ANTITERMINATION PROTEIN NUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_NusA_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26594">
        <property type="entry name" value="KH_NusA_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="338"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="663"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="664"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="710" mass="78138" checksum="E63C33882B8D4F0D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY27</accession>
    <name>A4RY27_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417856.1">
        <property type="nucleotide sequence ID" value="XM_001417819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY27"/>
    <dbReference type="GeneID" id="5002011"/>
    <dbReference type="Gramene" id="ABO96149">
        <property type="protein sequence ID" value="ABO96149"/>
        <property type="gene ID" value="OSTLU_94405"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94405"/>
    <dbReference type="HOGENOM" id="CLU_654512_0_0_1"/>
    <dbReference type="OrthoDB" id="10606718at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672971" evidence="1">
        <location>
            <begin position="27"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="420" mass="46811" checksum="8AA802A5F83B2323" modified="2007-05-15" version="1">MSTVDPFVYPMIARSLALFALSFVTAADRREDDATLRLELTLTTRVASASATLRVARRTMSHPEAFMRAFAEMLDAYGLEQTKMFSHATLFVPTASNCAVRFAKSLGAEWSRQVVESVGDEVQCWLILDFEWSGAQDSRTTFLRDTFGLFLNGLRAAMLFVDIGARVDEVVYDDERSTANAATVFVNCARRIGISDSTWAAIVRVVVGSIESRPFIDRDGISVYINGSLMPWRQTRAMVDHLWTLDERFKSFGLPPLRQDLTLDANAEHVVYFAPPCETTTTTTYVRRVTIHFLSTAAKPADVVCSAFPLAGVADAMKTTMTSDIPIRVSAELSTAGMFDALQILKRDDPMRFSSAEEKEFIETSDRIGRGVLAILESPSSDVARDFCSQRDADDEDWRRKVLSNLRSSRVYAANCVEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY67</accession>
    <name>A4RY67_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MAGE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_38527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417877.1">
        <property type="nucleotide sequence ID" value="XM_001417840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY67"/>
    <dbReference type="STRING" id="436017.A4RY67"/>
    <dbReference type="GeneID" id="5001928"/>
    <dbReference type="Gramene" id="ABO96170">
        <property type="protein sequence ID" value="ABO96170"/>
        <property type="gene ID" value="OSTLU_38527"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38527"/>
    <dbReference type="eggNOG" id="KOG4562">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103122_0_0_1"/>
    <dbReference type="OMA" id="KITYSWG"/>
    <dbReference type="OrthoDB" id="205198at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="1">
        <location>
            <begin position="13"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="228" mass="25070" checksum="DFDA78D1812423AF" modified="2007-05-15" version="1">MSAEERERLTSEVMRYVLFASHQNRGAPVLRSKIGEAMSAIGGAGTKKGAGSYIVALAQKKFLDIFGFEMIELSRAQSRNKRPAKTVNESQAASAKCYALRSVLPAQMRRKFVDDPSATAARGFAIVVAALVQISNGCIREETLFEQLAQLGVVSGEHLSENHAELGDVRALMALLVKRRIFMREHSSYDDPTMGYSYELAEGAEAIIGYENIDKFINESMRSQIATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYG5</accession>
    <name>A4RYG5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase II</fullName>
            <ecNumber evidence="5">3.5.4.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_15668</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 2 phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.25" evidence="5"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418385.1">
        <property type="nucleotide sequence ID" value="XM_001418348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYG5"/>
    <dbReference type="STRING" id="436017.A4RYG5"/>
    <dbReference type="GeneID" id="5002260"/>
    <dbReference type="Gramene" id="ABO96678">
        <property type="protein sequence ID" value="ABO96678"/>
        <property type="gene ID" value="OSTLU_15668"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15668"/>
    <dbReference type="eggNOG" id="KOG1284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020273_2_1_1"/>
    <dbReference type="OMA" id="CRDQLEA"/>
    <dbReference type="OrthoDB" id="60371at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10990:FF:000001">
        <property type="entry name" value="Riboflavin biosynthesis protein RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001591">
        <property type="entry name" value="PRK00393.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF47">
        <property type="entry name" value="GTP CYCLOHYDROLASE II DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="13">
        <location>
            <begin position="13"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="250" mass="28000" checksum="1BA7265AA5CAA49E" modified="2007-05-15" version="1">MSEDATLGLTRFVAETKLPTDKGFYRVRAYRHANPTTGDVTEPVCVIYGDVEGRENVPVRVHDACFTSEVLGSMKCDCKQQLEMAMDYIKENGPGIVCYLQQEGRGIGLANKIAAYAVQEEGVDTVDANRRLGLPDDTREYTAVENMLRELDVRSVQLMTNNPRKIRELECGGIKITGRIACVVKANLFNEGYLAAKERRMSHVLDQSWAYWDAKGNTYDSLDEMEGDFGDASTDETCEPFVNLNPKKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="112" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYV9</accession>
    <name>A4RYV9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_24671</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418230.1">
        <property type="nucleotide sequence ID" value="XM_001418193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYV9"/>
    <dbReference type="STRING" id="436017.A4RYV9"/>
    <dbReference type="GeneID" id="5002411"/>
    <dbReference type="Gramene" id="ABO96523">
        <property type="protein sequence ID" value="ABO96523"/>
        <property type="gene ID" value="OSTLU_24671"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24671"/>
    <dbReference type="eggNOG" id="KOG1494">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047181_0_1_1"/>
    <dbReference type="OMA" id="MNPLVTE"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF47">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="23"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="167"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="28"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="137"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO96523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="335" mass="34565" checksum="AE4D72A573308E1B" modified="2007-05-15" version="1">MFARALRRASNDAIARTRARGYKVAVLGAAGGIGQPCGLLMKMNPLVTELALYDIAGTPGVAADVSHVNTAAQTKGYAGDGELGAALKDADVVIIPAGVPRKPGMTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVNSTVPIAAEVLKAKGKYDARKLFGVTTLDVVRAKTFYAEKAGLETAKVDVPVVGGHAGITILPLFSQATPKASNLSEADIDALTKRTQDGGTEVVAAKAGKGSATLSMAYAGALFADACLRAKNGEANIVECTYVESKITDAAFFASKVTLGRDGVDTIHGLGSLTAYEQANLDAMIPQLQGEIKKGIDFVKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ03</accession>
    <name>A4RZ03_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418249.1">
        <property type="nucleotide sequence ID" value="XM_001418212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ03"/>
    <dbReference type="STRING" id="436017.A4RZ03"/>
    <dbReference type="GeneID" id="5002543"/>
    <dbReference type="Gramene" id="ABO96542">
        <property type="protein sequence ID" value="ABO96542"/>
        <property type="gene ID" value="OSTLU_24687"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24687"/>
    <dbReference type="HOGENOM" id="CLU_379663_0_0_1"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="730" mass="80978" checksum="4644F1618A1D5C81" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZC6</accession>
    <name>A4RZC6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nin one binding (NOB1) Zn-ribbon-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_41444</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NOB1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418551.1">
        <property type="nucleotide sequence ID" value="XM_001418514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZC6"/>
    <dbReference type="STRING" id="436017.A4RZC6"/>
    <dbReference type="GeneID" id="5002517"/>
    <dbReference type="Gramene" id="ABO96844">
        <property type="protein sequence ID" value="ABO96844"/>
        <property type="gene ID" value="OSTLU_41444"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41444"/>
    <dbReference type="eggNOG" id="KOG2463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024666_0_0_1"/>
    <dbReference type="OMA" id="XVKVSSS"/>
    <dbReference type="OrthoDB" id="446759at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09876">
        <property type="entry name" value="PIN_Nob1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000020">
        <property type="entry name" value="20S-pre-rRNA D-site endonuclease NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.210.10">
        <property type="entry name" value="Nin one binding (NOB1), Zn-ribbon-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039907">
        <property type="entry name" value="NOB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036283">
        <property type="entry name" value="NOB1_Zf-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014881">
        <property type="entry name" value="NOB1_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814:SF2">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17146">
        <property type="entry name" value="PIN_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08772">
        <property type="entry name" value="Zn_ribbon_NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144206">
        <property type="entry name" value="NOB1 zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease PIN" evidence="7">
        <location>
            <begin position="45"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Nin one binding (NOB1) Zn-ribbon-like" evidence="6">
        <location>
            <begin position="168"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="34215" checksum="8467DAD46326C7CD" modified="2007-05-15" version="1">MSAWSKIVRDDPAPAPVDAAEASAAAAAEATLESKLRDAATLKAVVDANAVFKGYALTDPNVLCVTIAEVLDEIRDAKGRDAVAASAGALEVAEPSEEAIEAVKRFASKTGDVHALSRVDMKLIALAYDLEGRFELESCVSSVTADYAMQNVILQMGLKLVAPDGMRIEHLRRWVLRCHACNEITRNLTRMFCPKCGNQTLQKVEHTVTRDGVEQFGVRKKFVLRGSKYTLPAPKGGRNAKKIILREDQLMSVRLTKKQVGEDVFAAEYNEESYADAKHFASQKTAYEIGGGDVRRNPNERRHVATNRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZK8</accession>
    <name>A4RZK8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418813.1">
        <property type="nucleotide sequence ID" value="XM_001418776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZK8"/>
    <dbReference type="STRING" id="436017.A4RZK8"/>
    <dbReference type="GeneID" id="5002748"/>
    <dbReference type="Gramene" id="ABO97106">
        <property type="protein sequence ID" value="ABO97106"/>
        <property type="gene ID" value="OSTLU_92965"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92965"/>
    <dbReference type="eggNOG" id="ENOG502S801">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_676790_0_0_1"/>
    <dbReference type="OMA" id="ESHEHEQ"/>
    <dbReference type="OrthoDB" id="498592at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="15"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="411" mass="45356" checksum="8561839760F1A6F5" modified="2007-05-15" version="1">MKVPTHDAAPGAKSYGGMGERVLRAMGWSKCARPTTEATDATDDRRRDARPRREERRLTARERPRARDRGDGLGKRRHGRAEAIEVVKREDNAGVGKRKTRYAWDEKWWEGTYANAASKIARVVGGEEDGKTTSSTSTSGRDGDSSESEDSSEDEVAARLGTATGRDGVAFSGSKSDLQLMRELAEDNHRGSTFGGRVGKLERIAKFEAEQLAKYGIQRGSASAPAAAETKKKPKEKSKKDKKKRKSDGEGAVETTVRPSGVSYEGEKSLSTKLSDWWTRAGFAWGGLVGSKRERDLNDDGAADDEDGADRAKRGKGFTENDQEALFKSAHETNVAKGTKRGLGGRGVLKSEWTGVRRTDFGDDDDDDVAKNDARRKNEKAKKEKKEKKDKKEKKQKKEKKEKSRTVEVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZQ7</accession>
    <name>A4RZQ7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_16013"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="435"/>
        </location>
    </feature>
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        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="537" mass="57685" checksum="D2A0B391DBEBE0AE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZU6</accession>
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        </submittedName>
    </protein>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418631.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZU6"/>
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    <dbReference type="Gramene" id="ABO96924">
        <property type="protein sequence ID" value="ABO96924"/>
        <property type="gene ID" value="OSTLU_16043"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16043"/>
    <dbReference type="HOGENOM" id="CLU_426669_0_0_1"/>
    <dbReference type="OMA" id="CCACQAR"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672052" evidence="2">
        <location>
            <begin position="26"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="642" mass="67718" checksum="3670B3D3BDBE0411" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZV0</accession>
    <name>A4RZV0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_92995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418633.1">
        <property type="nucleotide sequence ID" value="XM_001418596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZV0"/>
    <dbReference type="STRING" id="436017.A4RZV0"/>
    <dbReference type="GeneID" id="5002948"/>
    <dbReference type="Gramene" id="ABO96926">
        <property type="protein sequence ID" value="ABO96926"/>
        <property type="gene ID" value="OSTLU_92995"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92995"/>
    <dbReference type="eggNOG" id="KOG4133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1521664_0_0_1"/>
    <dbReference type="OMA" id="YMTSGAK"/>
    <dbReference type="OrthoDB" id="498344at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="7">
        <location>
            <begin position="74"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="177" mass="19500" checksum="25911C3FFCCA8AC0" modified="2007-05-15" version="1" fragment="single">VKRAKARAKAKRDGRGWGGGGAKRAKSAPATNVSGWEKVVAGESSFVSVPLTNDGDGEEEDARWSFPSTREERERYAVFKDLHDKSFYMTSGAKFGSDFLAYPGDPILFHAHYTVRIVSWDAVIHPLVIAATTRMSNAARKNFVVAAVRATDANGENFEVRYFTMEADVDLSSNRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S030</accession>
    <name>A4S030_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CobW/HypB/UreG nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_35690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418903.1">
        <property type="nucleotide sequence ID" value="XM_001418866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S030"/>
    <dbReference type="STRING" id="436017.A4S030"/>
    <dbReference type="GeneID" id="5002642"/>
    <dbReference type="Gramene" id="ABO97196">
        <property type="protein sequence ID" value="ABO97196"/>
        <property type="gene ID" value="OSTLU_35690"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35690"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_1_1_1"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF59">
        <property type="entry name" value="COBW C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="1">
        <location>
            <begin position="20"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="33465" checksum="031A6452262DA798" modified="2007-05-15" version="1" fragment="single">MFRNYELRTAYAATASRTLPITLVVGFLGAGKTTLARRALENRQTLRVAAAVNDFAALNVDARLDGRAAARVTELTNGCVCCSLRDDLERGVIELLNADENGGELGVFDYLLIETSGLVDPGEVVSRLDRNFGALTRARLDGVVCVVDAEIASEGGPEVEREAWDAQLACADVVLLNKIDLLEGDEERLARARAVVEDKARGARVLECVDANVPLTSILDVDMTEEQKIVVRGPLSLDPSRKTTHFAGGSQSSCNSLAHETTSPLVFARFQHWATKMMPAATIRAKGVLTLAEDENRESYDFHFSGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S038</accession>
    <name>A4S038_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_87757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418906.1">
        <property type="nucleotide sequence ID" value="XM_001418869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S038"/>
    <dbReference type="STRING" id="436017.A4S038"/>
    <dbReference type="GeneID" id="5002647"/>
    <dbReference type="Gramene" id="ABO97199">
        <property type="protein sequence ID" value="ABO97199"/>
        <property type="gene ID" value="OSTLU_87757"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87757"/>
    <dbReference type="eggNOG" id="ENOG502SB7S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753047_0_0_1"/>
    <dbReference type="OMA" id="YFEACDV"/>
    <dbReference type="OrthoDB" id="2015968at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042644">
        <property type="term" value="C:chloroplast nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038961">
        <property type="entry name" value="PRDA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37262">
        <property type="entry name" value="PROTEIN PEP-RELATED DEVELOPMENT ARRESTED 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37262:SF1">
        <property type="entry name" value="PROTEIN PEP-RELATED DEVELOPMENT ARRESTED 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37417" checksum="4EF6454270CA1EA4" modified="2007-05-15" version="1">MEDDDTAKRVDAASEVLDKIIRETVEGIFLEEAATEVLNEASAANEREAVESAVDKRAVLRAVVRSHFEELDGSFLAALGAYVRASEASGDLQLVSLLNAIKEETLATVTDSLTDEMQVVQLVARLKSNEERFEVIRVAHAGGGRALGDVDVPGVSVEKIERAAAQLIDELELQEQIPNWDLLYQVIVVRETARQLSKAADASGVYSDVVVSGSFAPSELPKAESALIKELVVVNTVAQRRALLAQMFDETRDKLDQDFDRSSGKVKLKKTTRGFQPRIERAAATAAGLDSRDLRPGRFIDSVINLRVSLLREGEESTPVVTRLGEIYYEMCDVVMENANVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S074</accession>
    <name>A4S074_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418925.1">
        <property type="nucleotide sequence ID" value="XM_001418888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S074"/>
    <dbReference type="GeneID" id="5002768"/>
    <dbReference type="Gramene" id="ABO97218">
        <property type="protein sequence ID" value="ABO97218"/>
        <property type="gene ID" value="OSTLU_93023"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93023"/>
    <dbReference type="HOGENOM" id="CLU_971110_0_0_1"/>
    <dbReference type="OrthoDB" id="10562844at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="287" mass="31093" checksum="9B44E15A5DC56ACF" modified="2007-05-15" version="1">MPTTTRAAFGDDVDACARATSDGVDVVCYRRRRSTRAPPLARVRARGTGAREREREAFDALRATMGTPRAWTANAEGCAMTPRAGERAEARAALETFIHERIFRALFGTTTAATAAGDAGVFAPHRGTNVMWHRDGYMAGAYVAHAILAAEEEEEEASGGKWFEHALVDADEDEESTTETFEVDFENQGILSKSVRKGNFVPIDARGGVLCVFEDAAVLHRSPKSAGKALDAMTRTIARFNFSAVDGSGRTVRIFAPDDASWTPFDDRGAVRGLTAMDGFDAYVRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S092</accession>
    <name>A4S092_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_35648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418703.1">
        <property type="nucleotide sequence ID" value="XM_001418666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S092"/>
    <dbReference type="STRING" id="436017.A4S092"/>
    <dbReference type="GeneID" id="5002689"/>
    <dbReference type="Gramene" id="ABO96996">
        <property type="protein sequence ID" value="ABO96996"/>
        <property type="gene ID" value="OSTLU_35648"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35648"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084247_3_1_1"/>
    <dbReference type="OMA" id="WWPTSEH"/>
    <dbReference type="OrthoDB" id="206452at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="1">
        <location>
            <begin position="9"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="169" mass="18859" checksum="C239B1E866CD10D3" modified="2007-05-15" version="1">MDNLPPVKFYKAWDEYGALSNFSPFPVSVDGVEWPTVEHYYQAQKFAGVHNDIARESFEKIKLAESPEAAAKIGRSAQAAHPESVRKDWDDVKVDVMRRALTEKLVRYEGPRTLLMESVCTDGRVRVIEDSPVDGVWGAGRDGTGQNLLGALLVNIREDLVSGRLDVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0M4</accession>
    <name>A4S0M4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_32797</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418766.1">
        <property type="nucleotide sequence ID" value="XM_001418729.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S0M4"/>
    <dbReference type="GeneID" id="5002791"/>
    <dbReference type="Gramene" id="ABO97059">
        <property type="protein sequence ID" value="ABO97059"/>
        <property type="gene ID" value="OSTLU_32797"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32797"/>
    <dbReference type="eggNOG" id="KOG1225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_249772_0_0_1"/>
    <dbReference type="OMA" id="FARYAYK"/>
    <dbReference type="OrthoDB" id="496415at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1060">
        <property type="entry name" value="NPCBM/NEW2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050969">
        <property type="entry name" value="Dev_Signal_Modulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038637">
        <property type="entry name" value="NPCBM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14949:SF56">
        <property type="entry name" value="EGF-LIKE-DOMAIN, MULTIPLE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14949">
        <property type="entry name" value="EGF-LIKE-DOMAIN, MULTIPLE 7, 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05345">
        <property type="entry name" value="He_PIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="960"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="964"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="985"/>
            <end position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1479" mass="160474" checksum="57B4790080D18C99" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0S8</accession>
    <name>A4S0S8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419030.1">
        <property type="nucleotide sequence ID" value="XM_001418993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0S8"/>
    <dbReference type="GeneID" id="5002852"/>
    <dbReference type="Gramene" id="ABO97323">
        <property type="protein sequence ID" value="ABO97323"/>
        <property type="gene ID" value="OSTLU_32850"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32850"/>
    <dbReference type="HOGENOM" id="CLU_843048_0_0_1"/>
    <dbReference type="OrthoDB" id="498371at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="37306" checksum="925B69ED983C59BB" modified="2007-05-15" version="1">MKDGDDATRKSRHLRDKRDAKLYGKMRELMTSDRGAPGAKAKVRNALKRVDSEFNQRGPDIALDRRDAEVMGLCRDVVSKEAWKRWSANACQDAVKNDSIERLKFLHECECPWGKCRFEATSLKILYVCAEHGSTECMKYLLKHGCKFSNHACTTAAEFGFLECLKYLREHGHHWDRWTCTGAARNGHLEMLKYAHENGCPWDENTCSSAAKRGHLECLKYAHEQGCPWNTLTCYNAASNGHLECLKYACTHGCPDSAPYAKALKEVVLPDADERFVVEVALVFHRSGEISMREFLPLWAEHRMFYRKAHYEAVRKFHASLRLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0X7</accession>
    <name>A4S0X7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_16331</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419054.1">
        <property type="nucleotide sequence ID" value="XM_001419017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0X7"/>
    <dbReference type="STRING" id="436017.A4S0X7"/>
    <dbReference type="GeneID" id="5003388"/>
    <dbReference type="Gramene" id="ABO97347">
        <property type="protein sequence ID" value="ABO97347"/>
        <property type="gene ID" value="OSTLU_16331"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16331"/>
    <dbReference type="eggNOG" id="KOG0376">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004962_1_1_1"/>
    <dbReference type="OMA" id="DPPWEGQ"/>
    <dbReference type="OrthoDB" id="445564at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="6">
        <location>
            <begin position="136"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="421" mass="46791" checksum="7CF51C8D29E940F4" modified="2007-05-15" version="1">MAMEIALPLTNEWVRKLATAMEANTHCSVPRRISKILSATEVEKLFTAVARVLKREKTLVRVRGDGDDDFDEVVVVGDTHGQYHDVLKLFELAGEPEKKKMFVFNGDFVDRGAWGVEVLLLLLARKALAPERVILLRGNHETEFCTECYGFERELSVKYGKTAGRRLYPMFLELCAALPLACKVGDATLILHGGLFRSASLSKREAATNPKLGTLAELEKASKGGADPIGEGRSMIAGDVLWSDPIPEDGLHHNENRGIGIQFGPAQTLEFLRNENLKLIIRSHEGPDARHDRPEMPSIMSGFCVDHDFGEDGKLCTLFSAPNYPQFIEVDDLRHNNLASFVTLSRATNFCDPVPTSFDAVPRPPSQCYYELDLNGSDAEGPESDIRPHEPLHIDVGEGDEGARWKEDELSHKLTLDRDQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4S120</accession>
    <name>A4S120_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419285.1">
        <property type="nucleotide sequence ID" value="XM_001419248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S120"/>
    <dbReference type="GeneID" id="5003360"/>
    <dbReference type="Gramene" id="ABO97578">
        <property type="protein sequence ID" value="ABO97578"/>
        <property type="gene ID" value="OSTLU_16362"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16362"/>
    <dbReference type="HOGENOM" id="CLU_1780554_0_0_1"/>
    <dbReference type="OMA" id="RALCIKQ"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="146" mass="16794" checksum="F1D6E6BD88A8AD27" modified="2007-05-15" version="1">MARVARAHENALRFDRTRASPAPPRARASRRARRVPARATHAGDNAGDLHERALCIKQRALNLARNRVRGGDYVNDDVTQMRGRKFEAEARVRRLKSDLNARLLLERFSEAREISREIERAEDEIDRIQLAIAAEQERAIERFEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2M8</accession>
    <name>A4S2M8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pseudouridine synthase RsuA/RluA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419777.1">
        <property type="nucleotide sequence ID" value="XM_001419740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2M8"/>
    <dbReference type="STRING" id="436017.A4S2M8"/>
    <dbReference type="GeneID" id="5003616"/>
    <dbReference type="Gramene" id="ABO98070">
        <property type="protein sequence ID" value="ABO98070"/>
        <property type="gene ID" value="OSTLU_16779"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16779"/>
    <dbReference type="eggNOG" id="KOG1919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1268737_0_0_1"/>
    <dbReference type="OMA" id="CMCISET"/>
    <dbReference type="OrthoDB" id="428658at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF87">
        <property type="entry name" value="RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="24884" checksum="31D618F950BD54A7" modified="2007-05-15" version="1">MENDADGNRVEKTRFTPRWDGDASCEDWLNLKYPGKHHRFCHQLDTATSGVVLTAHTREAAGNAAKLFRDRLAKKKYLAVVFGWPKEDEWTVNAKLGKDPTDVKGFRERVDEENGKASETSFKVLQRGYCTLDGANRGVEVSRLECRPVTGRRHQIRLHLMHSGHPILGDMAYSDDTDSYRMFLHALELVMPFEEETLTFATEPPESFNDVMSAERTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2U7</accession>
    <name>A4S2U7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419809.1">
        <property type="nucleotide sequence ID" value="XM_001419772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2U7"/>
    <dbReference type="GeneID" id="5003758"/>
    <dbReference type="Gramene" id="ABO98102">
        <property type="protein sequence ID" value="ABO98102"/>
        <property type="gene ID" value="OSTLU_25061"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25061"/>
    <dbReference type="HOGENOM" id="CLU_380104_0_0_1"/>
    <dbReference type="OMA" id="EFRQKEF"/>
    <dbReference type="OrthoDB" id="10481091at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="729" mass="79050" checksum="3A8E9D12C2D9E1CB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="113" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2V1</accession>
    <name>A4S2V1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">S-acyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Palmitoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_1452</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="9"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419599.1">
        <property type="nucleotide sequence ID" value="XM_001419562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2V1"/>
    <dbReference type="STRING" id="436017.A4S2V1"/>
    <dbReference type="GeneID" id="5003813"/>
    <dbReference type="Gramene" id="ABO97892">
        <property type="protein sequence ID" value="ABO97892"/>
        <property type="gene ID" value="OSTLU_1452"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1452"/>
    <dbReference type="eggNOG" id="KOG0509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031257_3_1_1"/>
    <dbReference type="OMA" id="RECQSHS"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009932">
        <property type="term" value="P:cell tip growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001006">
        <property type="term" value="P:regulation of cellulose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000652">
        <property type="term" value="P:regulation of secondary cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF17">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="31"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="10">
        <location>
            <begin position="335"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="493" mass="54055" checksum="47E4BF512EDA3B66" modified="2007-05-15" version="1" fragment="single">DIWRAAAYGNVDAMKRMIDADEGCVNAPDGSGFRALQWAALNNRVAAATLLLERGSSINAGDNDGQTALHWACVRGSLPCAELLLRKGAELNAADSRGYVPLHVAAQYGHTGMIYHFKMRWNIDVDVTDHDGRTALHWAAYKGFPDPVKLLVCMDADVYRADKEGCTALHWAAIKGKSEAAHLIVRAGGLNAMTAVDVDGNTAEALALEKGHHLLANFLAKEQRALLRRDNFWTQKGLAVACLGLIVGLMLMFSHYVIFAEGVATMDVTLSFWSLVSLASASCGLYYMKRVSQADPGVVTASILSSIRRGARPSSAAHDVDERLNHAELWAGNWNQLCVTCKFVKPFGTKHCAVRDKCVARFDHYCPWMGNTIGKRNHRDFVIFLILESLAMAIAFCVAIARFNEESPTERFRSTGGIACFAVFDALTLLPVALLTVAQLSQAARNITTNELSNVHRYAYLKSAEGRFANPFDRGSFARNLRAFFLVGKKEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2X0</accession>
    <name>A4S2X0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_16850</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419610.1">
        <property type="nucleotide sequence ID" value="XM_001419573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2X0"/>
    <dbReference type="STRING" id="436017.A4S2X0"/>
    <dbReference type="GeneID" id="5003877"/>
    <dbReference type="Gramene" id="ABO97903">
        <property type="protein sequence ID" value="ABO97903"/>
        <property type="gene ID" value="OSTLU_16850"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16850"/>
    <dbReference type="eggNOG" id="KOG2445">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_835196_0_0_1"/>
    <dbReference type="OrthoDB" id="508132at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="283"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="333" mass="35205" checksum="0C70BAFF263E3E21" modified="2007-05-15" version="1">MPTDAAPRCVAYDDTRTACVVGTAAGEIVFRERASSASALDAAAVEDHSKPSASPWTRQASARAADDTSAIVDIALSDAAHGRVIAAATASGEVSFWRASASGDSNGTPRVERVGLVRVEGGAKARCVAFAPSHDALTLAAACDDGVVRFYEPREKLTATAWESTLEFEGKKPGGDATALAWRRSSERTSAVNVPILAVGTTWTSEARHGVSVLAYDEKFRRWNVVTEMEDGLTTSARHLAWSATTTARGALNLVVASGSKCLVYEFTGVVMRGVEDAKQIGRLDHPCEVNSAEWNASGSVIATAAADGVVRLWSANLKDGTWREQTMGQTMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S392</accession>
    <name>A4S392_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_50709</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419840.1"/>
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    <dbReference type="STRING" id="436017.A4S392"/>
    <dbReference type="GeneID" id="5004243"/>
    <dbReference type="Gramene" id="ABO98170">
        <property type="protein sequence ID" value="ABO98170"/>
        <property type="gene ID" value="OSTLU_50709"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50709"/>
    <dbReference type="eggNOG" id="KOG0947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002902_4_0_1"/>
    <dbReference type="OMA" id="RRGCDKA"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
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        <property type="term" value="C:cytoplasmic stress granule"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901259">
        <property type="term" value="P:chloroplast rRNA processing"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016554">
        <property type="term" value="P:cytidine to uridine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000373">
        <property type="term" value="P:Group II intron splicing"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010497">
        <property type="term" value="P:plasmodesmata-mediated intercellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016441">
        <property type="term" value="P:post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="112"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="382"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="810"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1055" mass="117234" checksum="CBF77B5659C05C5B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3L0</accession>
    <name>A4S3L0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">persulfide dioxygenase</fullName>
            <ecNumber evidence="12">1.13.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Sulfur dioxygenase ETHE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_38033</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12981"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58905"/>
            <dbReference type="EC" id="1.13.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.18" evidence="12"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420113.1">
        <property type="nucleotide sequence ID" value="XM_001420076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3L0"/>
    <dbReference type="STRING" id="436017.A4S3L0"/>
    <dbReference type="GeneID" id="5004067"/>
    <dbReference type="Gramene" id="ABO98406">
        <property type="protein sequence ID" value="ABO98406"/>
        <property type="gene ID" value="OSTLU_38033"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38033"/>
    <dbReference type="eggNOG" id="KOG0814">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_7_0_1"/>
    <dbReference type="OMA" id="VMDIDYA"/>
    <dbReference type="OrthoDB" id="449487at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070813">
        <property type="term" value="P:hydrogen sulfide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000013">
        <property type="entry name" value="Persulfide dioxygenase ETHE1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051682">
        <property type="entry name" value="Mito_Persulfide_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084:SF1">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="14">
        <location>
            <begin position="37"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00077964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="258" mass="28270" checksum="AD24CEE1D93FCEF7" modified="2007-05-15" version="1">MDLKFFSKPPLADFVREGLRPDAGLIFRQLFDTSGSSTYTYLLGDPVSKEAVLIDPLKEMVDRDLAVVNDLGLKLKYAINTHCHADHITGSGDLKAKVTGLQSVIAESSGARADVHIKHGDVISFGADSNVINLEVRATPGHTDGCVSYVCDNMVFTGDALLIRGCGRTDFQGGSSEKLYDSVRTQLFELPDETLVYPAHDYKGRMVSTIGEEKELNPRLGLKKTKEEFVEIMSNLNLAYPKKIDESLPANLKCGIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4S400</accession>
    <name>A4S400_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_17136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420181.1">
        <property type="nucleotide sequence ID" value="XM_001420144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S400"/>
    <dbReference type="GeneID" id="5003966"/>
    <dbReference type="Gramene" id="ABO98474">
        <property type="protein sequence ID" value="ABO98474"/>
        <property type="gene ID" value="OSTLU_17136"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17136"/>
    <dbReference type="HOGENOM" id="CLU_1153320_0_0_1"/>
    <dbReference type="OMA" id="LMVESAH"/>
    <dbReference type="OrthoDB" id="10604664at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="241" mass="26223" checksum="9BD905E62AA17203" modified="2007-05-15" version="1">MTRDGIASSDSKIALSSVYRDGDNVALTSPDALVLSFVADAAFDGDEDAARAAVERVEMLIPSLRAAGRKASTGAPTLARWARDVDALCAALVSLRRALPSCDVADFVLKTPRLLFDCDHDELKKTLDELRELFPNAGKDGKPDVDRMAQAVPQILDVEFTRAGLRALRDSGAFGDADPAELVHAVPSRILMVESAHLRSSFSPNFDQTHVRAGKVARVGRRESYYDDHGIVARDPEQPHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4A2</accession>
    <name>A4S4A2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="9">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_17209</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="9"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420396.1">
        <property type="nucleotide sequence ID" value="XM_001420359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4A2"/>
    <dbReference type="STRING" id="436017.A4S4A2"/>
    <dbReference type="GeneID" id="5004540"/>
    <dbReference type="Gramene" id="ABO98689">
        <property type="protein sequence ID" value="ABO98689"/>
        <property type="gene ID" value="OSTLU_17209"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17209"/>
    <dbReference type="eggNOG" id="KOG0366">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028946_3_0_1"/>
    <dbReference type="OMA" id="AESHCGQ"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000012">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="10">
        <location>
            <begin position="16"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="36595" checksum="BDB8FC45EF43EBF6" modified="2007-05-15" version="1">MSSLADEVTTIAFESLAVDAHASFIVNASASEDTLEHAFTEHLRLSGIYWGVCALATMGNLRKTMDADKREEILSYVASCRCESGAYSGGAGHDGHVLYTLSAVQIYALFDAMDRIDRDSVVNYVKGLQLADGSFQGDEWGEVDTRFTYCALSTLRLLDRLHEVDVEAACAYINKCKNFDGGFGATPGGESHAGQVFTCVGALAIGNRLDYVDGDLLGWWLAERQVKVGGLNGRPEKLPDVCYSWWVLSALSILGKTHWIDRGALARFILRCQDETSGGISDRPDDEPDVYHTFFGIAGLSLMGHPAVVEPIDPVFALPNSVLKQLGIEPWSARKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4P2</accession>
    <name>A4S4P2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_2491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420302.1">
        <property type="nucleotide sequence ID" value="XM_001420265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4P2"/>
    <dbReference type="STRING" id="436017.A4S4P2"/>
    <dbReference type="GeneID" id="5004546"/>
    <dbReference type="Gramene" id="ABO98595">
        <property type="protein sequence ID" value="ABO98595"/>
        <property type="gene ID" value="OSTLU_2491"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2491"/>
    <dbReference type="eggNOG" id="KOG2026">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016848_4_0_1"/>
    <dbReference type="OMA" id="QLRRFKC"/>
    <dbReference type="OrthoDB" id="10263353at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF16">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="5">
        <location>
            <begin position="125"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="48130" checksum="0FA238D95B8BE20C" modified="2007-05-15" version="1" fragment="single">CPYLDTVNLANLDFDFEKRCAVSLSPVHVYACLVCGKYFAGRGKKTHAYAHALECGHHVFMRLADGAAWCLPDGYEVVDEGTTLSRIRDVLAPTYAKKYVEEEIEGARPMWRRALDGTEFLVGVVGLNAIWSKRDDGVSAVLQSLNRVAPLRRALLLDDAREREDVYRALADITKKIWNARNFKGHSSPHEFMQAVRNRSKDAFGAETGNHDAAQFLRWLLNELIRDEKKRGEKRSVIQSCFQGEVEIIDDSSASRASPFLMLSMDLPNAPLFQDVMEKNIIPQVSLERALLKKFDGVTADPKTRRRFKITKLPNYLIVNYSRFTKNNFFVEKNPTIVTFPTRGLNLADHIPVPRGDENSATYDLIANIVHDGAPDDGSYRAMVYHAPDKNWYETQDLRVAEVLPQQVNLTETYVQIYERRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4P6</accession>
    <name>A4S4P6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleoside phosphatase GDA1/CD39</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_3043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420472.1">
        <property type="nucleotide sequence ID" value="XM_001420435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4P6"/>
    <dbReference type="STRING" id="436017.A4S4P6"/>
    <dbReference type="GeneID" id="5004548"/>
    <dbReference type="Gramene" id="ABO98765">
        <property type="protein sequence ID" value="ABO98765"/>
        <property type="gene ID" value="OSTLU_3043"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3043"/>
    <dbReference type="eggNOG" id="KOG1385">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010246_0_0_1"/>
    <dbReference type="OMA" id="YNDKQYD"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009134">
        <property type="term" value="P:nucleoside diphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF83">
        <property type="entry name" value="GUANOSINE-DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="160"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="42940" checksum="9571AEBC0AB8BD73" modified="2007-05-15" version="1" fragment="single">TRYAVVIDAGSTGTRVHVFTFSRSAFASGGEALRDETFRSIEPGLKSYGGDAEAAATSIEALIDVAKGVVPESARRETPFSVRATAGLRLMPEGREAADAIVEAVRRKIANAGFHPSSASFVSIMDGEDEGAHAWVSVNYLLGNLGGAPEKTVTVVDLGGGSTQIAYAVGGGAAKDAPKGYVRDIEAASTTYRTYVHSFKGYGIVAVRPKIFSVGKNKDGSHPCLPNAFADSCEKDCYGLEPGETYAAIGSSDGSDFTRCLLATTQALEGNCAKAPCSFAGAWTTPRKTPLFVMSFIVERAIQGGAVPPPRRPTDIATMTPRDVKRAALRACSTPAAELEARFPVAARDAVDVNYLCLDLVYVYALLTVGHGAADDETIRALDKIRYRRRDVEASWALGDGIAAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Q0</accession>
    <name>A4S4Q0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420305.1">
        <property type="nucleotide sequence ID" value="XM_001420268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Q0"/>
    <dbReference type="STRING" id="436017.A4S4Q0"/>
    <dbReference type="GeneID" id="5004599"/>
    <dbReference type="Gramene" id="ABO98598">
        <property type="protein sequence ID" value="ABO98598"/>
        <property type="gene ID" value="OSTLU_26487"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26487"/>
    <dbReference type="eggNOG" id="KOG3126">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086787_0_0_1"/>
    <dbReference type="OMA" id="CHTVNAN"/>
    <dbReference type="OrthoDB" id="495246at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="269" mass="27693" checksum="3808F4E3FB21DDBC" modified="2007-05-15" version="1">MAKYYGDIAKSAKDLLTGGFNYDTKVSVDTKSAGTGVSASVVQKGEAVSGDLKVNANVVDQVIDIELNQDAKAKVTASFPSLIPNGKLSVGGTVQDLETVKVSASVLAGPLGVKADVANYAAPKADASLCYAIGGGFAVGAMATIKSSSALAYTVAAQSKQGDVTYALTAADQFKTFKASVVTALDSKQTLGAEVVYKKAATATIGYSKKMDGHSFKAVVANPVSAEFNPTLSVHASLGSLIPKTTATISCQVDKTMKYKYGFQFATKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4U9</accession>
    <name>A4S4U9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420500.1">
        <property type="nucleotide sequence ID" value="XM_001420463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4U9"/>
    <dbReference type="GeneID" id="5004508"/>
    <dbReference type="Gramene" id="ABO98793">
        <property type="protein sequence ID" value="ABO98793"/>
        <property type="gene ID" value="OSTLU_25248"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25248"/>
    <dbReference type="HOGENOM" id="CLU_971106_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="287" mass="31766" checksum="FAFEE94931C9A6D3" modified="2007-05-15" version="1">MNRCRRGDMCLRHPARLCAAVAVAIFDWRLVLVESYPTELRLDARCEGGMARVHPTRRAAGHGAPIDATNTSVLLSWANHTDVEDAQYDENEPTRQIPAAWTFPPGKREYCDGCRLGLAASHEDPNSMMLITASAGSFHDQGVLLNGNVNRPATACSGRRMYTTRKATVHNLIWCAPEKSASIETVEFHITASGGASMPFKRYVFVLQRNITLEPDEDLHGALCFASERSPQNSYFSCLTLVYVTLGLLATTMVSVWAVSTRARRSRCRYSALGAEALDREIEMPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S504</accession>
    <name>A4S504_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420358.1">
        <property type="nucleotide sequence ID" value="XM_001420321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S504"/>
    <dbReference type="GeneID" id="5004419"/>
    <dbReference type="Gramene" id="ABO98651">
        <property type="protein sequence ID" value="ABO98651"/>
        <property type="gene ID" value="OSTLU_26592"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26592"/>
    <dbReference type="HOGENOM" id="CLU_200021_0_0_1"/>
    <dbReference type="OMA" id="MXKGDAD"/>
    <dbReference type="OrthoDB" id="538085at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="75" mass="7684" checksum="1674DF6F87F8AB45" modified="2007-05-15" version="1">MDVSGVGESAGGETGAAAAAAAAAAAPARTPRKKYEDVDESELVPGTTLPDGRVVVEDWKGDPMVLNPGDRMPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S544</accession>
    <name>A4S544_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_9831</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420379.1">
        <property type="nucleotide sequence ID" value="XM_001420342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S544"/>
    <dbReference type="STRING" id="436017.A4S544"/>
    <dbReference type="GeneID" id="5004440"/>
    <dbReference type="KEGG" id="olu:OSTLU_9831"/>
    <dbReference type="eggNOG" id="KOG1493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115512_0_2_1"/>
    <dbReference type="OMA" id="QWRWDTG"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16456">
        <property type="entry name" value="RING-H2_APC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="23"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="85" mass="9172" checksum="51A54CD62F4D96E0" modified="2007-05-15" version="1" fragment="single">LNVKTWHGVGAWTWGAGDVGDVCGICRIAFDGCPPDAKFPGDDSPVVWGKCGHAFHLQCITKWLSGANAEAPRCPICRGAWEFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S555</accession>
    <name>A4S555_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420383.1">
        <property type="nucleotide sequence ID" value="XM_001420346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S555"/>
    <dbReference type="GeneID" id="5004499"/>
    <dbReference type="Gramene" id="ABO98676">
        <property type="protein sequence ID" value="ABO98676"/>
        <property type="gene ID" value="OSTLU_26643"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26643"/>
    <dbReference type="HOGENOM" id="CLU_2007773_0_0_1"/>
    <dbReference type="OMA" id="MFFANAG"/>
    <dbReference type="OrthoDB" id="10364014at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="124" mass="13435" checksum="0AAB777873D4F736" modified="2007-05-15" version="1">MAIDKLMMISGAGTLSYGVQMKFMPKVASKMYWKEGERNNIDTVQSGWLGTVLLGSGALQVMSALDGECTKNQMGGAALAWAVTLPEYVAQRDDFKGPMLYANTAMATALTAVLVKSYLDKRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5A3</accession>
    <name>A4S5A3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420740.1">
        <property type="nucleotide sequence ID" value="XM_001420703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5A3"/>
    <dbReference type="GeneID" id="5004809"/>
    <dbReference type="Gramene" id="ABO99033">
        <property type="protein sequence ID" value="ABO99033"/>
        <property type="gene ID" value="OSTLU_26692"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26692"/>
    <dbReference type="eggNOG" id="ENOG502SH33">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027633_1_1_1"/>
    <dbReference type="OMA" id="YNQARTE"/>
    <dbReference type="OrthoDB" id="418661at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="411" mass="44757" checksum="5159290720FD93CB" modified="2007-05-15" version="1">MRVQWTHGYASAPSGFARCTHGFGEILAGMQPAACDLIMRECFEATETRSVLDPFAGGGTTLVCAQTLGWRAVGADVSPLACFVSANRNWRASEEEVEVMLESARTVTDRAGTREEKDGANDEDASDVPRSWRAVRDALREYLASDAFVGAPRVAEGLWFCMSVALQRTQKSQNKRRHKGKSKGKRGGGGDDASRVNAETFLKTVEEYANRLEQFREECAKHAGAPAPPASIHNVDVRKFKLSAEDKVDAVLTSCPYPAVYDYLSFARKVRAGSGAVVPSSASFSARSGPTSSYVNTVVPGDRNWPAGWTEGEIGSRRALRSDPYAFKDVWQREQEEWLAVVADSLTPRGRAAIMVGDGANIDTRASIVAAAAKFALREVAGCTMKLTTTTEEGRVYNQARTEHLILFDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5C5</accession>
    <name>A4S5C5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-15 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase 15 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_26714</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFS5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420583.1">
        <property type="nucleotide sequence ID" value="XM_001420546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5C5"/>
    <dbReference type="STRING" id="436017.A4S5C5"/>
    <dbReference type="GeneID" id="5004819"/>
    <dbReference type="Gramene" id="ABO98876">
        <property type="protein sequence ID" value="ABO98876"/>
        <property type="gene ID" value="OSTLU_26714"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26714"/>
    <dbReference type="eggNOG" id="ENOG502S4B1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162182_2_0_1"/>
    <dbReference type="OMA" id="SRCFAYW"/>
    <dbReference type="OrthoDB" id="495317at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24141">
        <property type="entry name" value="NDUFS5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019342">
        <property type="entry name" value="NADH_UbQ_OxRdtase_FeS-su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR619342-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO98876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="11361" checksum="FC8A773DBD72DB5D" modified="2007-05-15" version="1">MASGFGARGSEGRCAPVWREFTKCVNEADDRSACFKFREDYVECLHHKKEYRRENEIENERQRRNEEHANAKKEALLKEMRTFSWVTDEKYAPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5E5</accession>
    <name>A4S5E5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26734</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420763.1">
        <property type="nucleotide sequence ID" value="XM_001420726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5E5"/>
    <dbReference type="STRING" id="436017.A4S5E5"/>
    <dbReference type="GeneID" id="5004832"/>
    <dbReference type="Gramene" id="ABO99056">
        <property type="protein sequence ID" value="ABO99056"/>
        <property type="gene ID" value="OSTLU_26734"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26734"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_513290_0_0_1"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="134"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="450"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="531" mass="56486" checksum="845A3D7A38CCB1E9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5J2</accession>
    <name>A4S5J2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_17563</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5J2"/>
    <dbReference type="SMR" id="A4S5J2"/>
    <dbReference type="STRING" id="436017.A4S5J2"/>
    <dbReference type="GeneID" id="5004618"/>
    <dbReference type="Gramene" id="ABO99074">
        <property type="protein sequence ID" value="ABO99074"/>
        <property type="gene ID" value="OSTLU_17563"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17563"/>
    <dbReference type="eggNOG" id="KOG0776">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_0_0_1"/>
    <dbReference type="OMA" id="YMILKAE"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000001">
        <property type="entry name" value="Geranylgeranyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054848">
        <property type="entry name" value="GGPPSyn_CRT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053378">
        <property type="entry name" value="Prenyl_diphosphate_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045485">
        <property type="entry name" value="FPPsyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045685">
        <property type="entry name" value="GGPPSynCrtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43281">
        <property type="entry name" value="FARNESYL DIPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43281:SF1">
        <property type="entry name" value="FARNESYL DIPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="33488" checksum="87004EF2DC5D1AD1" modified="2007-05-15" version="1">MGRVRAVSATPDVSSEQEFNAYIKNVNAEIERALDASVPMHYPERLSESMRYSLLAGGKRIRPALCLAACELVGGTMEVAMPTACALEMIHTMSLIHDDLPSMDNDDFRRGKPTNHKVYGEEMAILAGDALLSHAFEYIGRETKGVSADKVLRVIVDVGKCVGSEGLVGGQVVDIMSEGADEGTVTIDTLKYIHAHKTGALLEVSVTAGAILGGASEEQIGKLERYAQNIGLAFQVVDDILDCTATSEELGKTAGKDMAVGKSTYPSLVGMEESKRIAADLISKAKQELEGFDPVKVKPLIGLADYIQNRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5L2</accession>
    <name>A4S5L2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_26805</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420627.1">
        <property type="nucleotide sequence ID" value="XM_001420590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5L2"/>
    <dbReference type="STRING" id="436017.A4S5L2"/>
    <dbReference type="GeneID" id="5004659"/>
    <dbReference type="Gramene" id="ABO98920">
        <property type="protein sequence ID" value="ABO98920"/>
        <property type="gene ID" value="OSTLU_26805"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26805"/>
    <dbReference type="eggNOG" id="ENOG502QT73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054288_0_0_1"/>
    <dbReference type="OMA" id="QHNGQEN"/>
    <dbReference type="OrthoDB" id="3219396at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052121">
        <property type="entry name" value="F-box_SCF_Substrate_Recog"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46550">
        <property type="entry name" value="F-BOX ONLY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46550:SF1">
        <property type="entry name" value="F-BOX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="40"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="30440" checksum="4A2BADC7BC262DF8" modified="2007-05-15" version="1">MLERRDDDGENAKKRPRVSRAADEGAVEEAEAGPFSTLHDDVVSLILRFLAPNELTSLAQTCKFFAARCDQDFLWRQCYLERFGNTKQAQGNGMKKLYLAADAMEINRERTKAPAGFEKICAEACAAKRSRQNAVLAPLCEQLATDRAASEWKSHRQFATDADSHVCSRRAGCSYAELPSNVFVCERTGKVHVCDDTCSERYLDTEIGTEICEVSGRVLDTVAADDEDEDPQAAAEQDQHYFEKGYFGRAFEVGYGCDNEAELATALWGGRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5M4</accession>
    <name>A4S5M4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420797.1">
        <property type="nucleotide sequence ID" value="XM_001420760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5M4"/>
    <dbReference type="STRING" id="436017.A4S5M4"/>
    <dbReference type="GeneID" id="5004634"/>
    <dbReference type="Gramene" id="ABO99090">
        <property type="protein sequence ID" value="ABO99090"/>
        <property type="gene ID" value="OSTLU_26816"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26816"/>
    <dbReference type="eggNOG" id="ENOG502QR55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048127_3_1_1"/>
    <dbReference type="OMA" id="NKVDPQQ"/>
    <dbReference type="OrthoDB" id="549925at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521:SF0">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="230" mass="25452" checksum="AD846710FAAA35BD" modified="2007-05-15" version="1">MPPIAHEGAIKLWNGGDREQWRAHAAAYDERLRALNLGERLSKLDAFVRKELPKTIAQRRATSATSDDWGYIKKDEYVRVVEWKLARGKTRPGLMKYAQALSERDVESASREAYRLAHASEGGKRNSKGKIVDAMAPFIALKGCGPATASILMAVGDERFPFFSDEALAVVVGNGGNDRYSAARYHEFMKALHRKCDDLGADDLTPAKLESALWSAAALTMPKKMAKTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5W1</accession>
    <name>A4S5W1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420839.1">
        <property type="nucleotide sequence ID" value="XM_001420802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5W1"/>
    <dbReference type="STRING" id="436017.A4S5W1"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="5004878"/>
    <dbReference type="Gramene" id="ABO99132">
        <property type="protein sequence ID" value="ABO99132"/>
        <property type="gene ID" value="OSTLU_26901"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26901"/>
    <dbReference type="HOGENOM" id="CLU_285969_0_0_1"/>
    <dbReference type="OMA" id="NEPAHLM"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF38">
        <property type="entry name" value="X8 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="461"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="522"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="596"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="644"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="929"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="523"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="560"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="597"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="685"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="709"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="935"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="948"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="977"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1006"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1026"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1047"/>
            <end position="1069"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1082" mass="119074" checksum="43051BD2A4E1FC28" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6C5</accession>
    <name>A4S6C5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_27069</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Golgi apparatus</location>
            <location evidence="5">Golgi stack membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420919.1">
        <property type="nucleotide sequence ID" value="XM_001420882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6C5"/>
    <dbReference type="CAZy" id="GT10">
        <property type="family name" value="Glycosyltransferase Family 10"/>
    </dbReference>
    <dbReference type="GeneID" id="5005125"/>
    <dbReference type="Gramene" id="ABO99212">
        <property type="protein sequence ID" value="ABO99212"/>
        <property type="gene ID" value="OSTLU_27069"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27069"/>
    <dbReference type="eggNOG" id="KOG2619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_414110_0_0_1"/>
    <dbReference type="OMA" id="PLREWAH"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046920">
        <property type="term" value="F:alpha-(1-&gt;3)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929">
        <property type="entry name" value="ALPHA- 1,3 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929:SF194">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671894" description="Fucosyltransferase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="8">
        <location>
            <begin position="408"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="708" mass="78228" checksum="76C1D172D0C7FD31" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6D6</accession>
    <name>A4S6D6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_13176</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421075.1">
        <property type="nucleotide sequence ID" value="XM_001421038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6D6"/>
    <dbReference type="STRING" id="436017.A4S6D6"/>
    <dbReference type="GeneID" id="5005131"/>
    <dbReference type="Gramene" id="ABO99368">
        <property type="protein sequence ID" value="ABO99368"/>
        <property type="gene ID" value="OSTLU_13176"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13176"/>
    <dbReference type="eggNOG" id="KOG0831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023995_0_1_1"/>
    <dbReference type="OMA" id="RMVHIYP"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO99368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="338" mass="38157" checksum="F36ED1B14EC8E37F" modified="2007-05-15" version="1">MIYAWILSAIFVYPAYCVFGPSMWLKNFFLGYIAWYATLDRKTASSGKRFARWSRRLPFWRILAEYFPVRLHVSAKLDPSGNYLFGYHPHGVIGVGALLTFATEATGFYEAFPGLDLRLLTLSMNFKFPFTREVLMGLGINSVTKSSVETNLTRAPGASVAIVIGGASEALDARPGWATLTLARRKGFVKMALRTGASLVPVFAFGENDIFEQVENPEGGRLRNFQMYIKQLIGITPPAFYGRSLSRGMWRRIFGRKGVLPKREPIEVVVGNPIAVPKVVDPSNEIIDKYHALYTESLKELYELHRRQFHRLNRGGSSDDLLSDLLTRQGKLQNMQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6H1</accession>
    <name>A4S6H1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420942.1">
        <property type="nucleotide sequence ID" value="XM_001420905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6H1"/>
    <dbReference type="GeneID" id="5004949"/>
    <dbReference type="Gramene" id="ABO99235">
        <property type="protein sequence ID" value="ABO99235"/>
        <property type="gene ID" value="OSTLU_17830"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17830"/>
    <dbReference type="HOGENOM" id="CLU_957759_0_0_1"/>
    <dbReference type="OrthoDB" id="10622915at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="291" mass="32216" checksum="3462D82069F0A412" modified="2007-05-15" version="1">MARDPRGLDLLLRAARTATEARARDRDETVKKSTTVRFQTADATGRVEAKTRRQGKARADGAMRDRTNDFERGGTAGKGKRGRGRATMTMKAKANAPPPDVDDSAEATTVREETLAIGAETLAREHADVVIERVRQWLDVMMSDARGRLTALERSQTRTHRALEKYDSEEAQDDVGIEMLVEFDKTLEIERSILEETMKNLEAMRTKVEFESANLALRWLRRSNCGGDDDGQASEEDQATDGRKYFYSSSAYAFLQTAIGAFMNDTTPAKSAKSADAHSPSGVLDAARLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6U3</accession>
    <name>A4S6U3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27241</name>
        <name evidence="2" type="ORF">OSTLU_29669</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421153.1">
        <property type="nucleotide sequence ID" value="XM_001421116.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422802.1">
        <property type="nucleotide sequence ID" value="XM_001422765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6U3"/>
    <dbReference type="STRING" id="436017.A4S6U3"/>
    <dbReference type="GeneID" id="5005211"/>
    <dbReference type="GeneID" id="5006860"/>
    <dbReference type="Gramene" id="ABO99446">
        <property type="protein sequence ID" value="ABO99446"/>
        <property type="gene ID" value="OSTLU_27241"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01161">
        <property type="protein sequence ID" value="ABP01161"/>
        <property type="gene ID" value="OSTLU_29669"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27241"/>
    <dbReference type="KEGG" id="olu:OSTLU_29669"/>
    <dbReference type="HOGENOM" id="CLU_147676_0_0_1"/>
    <dbReference type="OMA" id="WIALYAT"/>
    <dbReference type="OrthoDB" id="501859at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="148" mass="15829" checksum="8BE1A707170D52A3" modified="2007-05-15" version="1">MVAAIARPNAACAALAAACALATRDGKRRADLRRALMRGEGGGENETEETAPVMEFTAKDATVLMERAAKAAERAASVAEWRSRTVSAATMYAAMALSGVSAFVRADVMMCAIALYATRPARLRVIPDPINACWSRLPSLWKDQSKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6W7</accession>
    <name>A4S6W7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_27268</name>
        <name evidence="10" type="ORF">OSTLU_29643</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421165.1">
        <property type="nucleotide sequence ID" value="XM_001421128.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422790.1">
        <property type="nucleotide sequence ID" value="XM_001422753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6W7"/>
    <dbReference type="GeneID" id="5005223"/>
    <dbReference type="GeneID" id="5006848"/>
    <dbReference type="Gramene" id="ABO99458">
        <property type="protein sequence ID" value="ABO99458"/>
        <property type="gene ID" value="OSTLU_27268"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01149">
        <property type="protein sequence ID" value="ABP01149"/>
        <property type="gene ID" value="OSTLU_29643"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27268"/>
    <dbReference type="KEGG" id="olu:OSTLU_29643"/>
    <dbReference type="eggNOG" id="ENOG502ST3G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_974326_0_0_1"/>
    <dbReference type="OMA" id="CAYHINY"/>
    <dbReference type="OrthoDB" id="496403at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007635058" description="TLC domain-containing protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="32"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP01149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="246" mass="27579" checksum="9DDA2E1A55AC0DB0" modified="2007-05-15" version="1">MSIACNAFIMLVSLCFSRRVVGAKRFDAMKPHERTTWHTNLCTFWPAFAVTAYALPAIATFSGKSDSFVSDVSALTSKACGLSIGYMTWDLGVILARWDDQVVAYGGKGALYLFIVHHVFSIVLWPYALMRHLCAYHINYFLVSEVTNFNMSLRWILAALNMSNTKLYLINGLAWIPLFLGVRVVVIPRLFAAYMNSDWGVLTTPQYYAALLTLPIPSLLNLYWAQQIVVGAAKFLITGEDVLKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S760</accession>
    <name>A4S760_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="3 11">2.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_43090</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="3 11"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421216.1">
        <property type="nucleotide sequence ID" value="XM_001421179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S760"/>
    <dbReference type="STRING" id="436017.A4S760"/>
    <dbReference type="GeneID" id="5005483"/>
    <dbReference type="Gramene" id="ABO99509">
        <property type="protein sequence ID" value="ABO99509"/>
        <property type="gene ID" value="OSTLU_43090"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43090"/>
    <dbReference type="eggNOG" id="KOG2648">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037146_2_1_1"/>
    <dbReference type="OMA" id="WTPRHGM"/>
    <dbReference type="OrthoDB" id="1649088at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990145">
        <property type="term" value="P:maintenance of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11850:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035435">
        <property type="entry name" value="DPH1/DPH2_euk_archaea"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004967">
        <property type="entry name" value="DPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01121">
        <property type="entry name" value="Diphthamide_biosynthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="452" mass="50280" checksum="73A52E899CF30800" modified="2007-05-15" version="1">MTDADPPSTSSAVDVRETTTAPVVRRFVRNQVRTRRSRVVPLAEKCPEPKLTAPTQIPDEIANDPELETAMKVLPVNYDFEVKKTVWRLRQVGVKTLALQFPEGLLLYATTLSDIFQTFAGVRDVVILGDVTYGACCVDDYTAESLGCDFLVHYGHSCLVPVDVTRMKCLYVFVDISFDVGHLCASVEHNFKPGSRLILAGTIQFASAIQETRTRLAERYPSLAVPQAKPLSPGEVLGCTAPVIEDAKDRDAIVFVADGRFHLEAIMIANPTVPAFRYDPYQRILTREEYAHKEMRSVRKSMVSRAKDAKTFGIVLGTLGRQGNPAILEHLMSLMRVKGREYVVFLISEMNPAKMAALEGLDAFVQVACPRLSIDWGEEFDRPVLTPYEAEVALDNVEPWWLLAGVAPGEEYAPYPMDYYAKDGGSWSSSYHKQTGKNGKPKRAPVRIETAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7M9</accession>
    <name>A4S7M9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421300.1">
        <property type="nucleotide sequence ID" value="XM_001421263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7M9"/>
    <dbReference type="GeneID" id="5005457"/>
    <dbReference type="KEGG" id="olu:OSTLU_93716"/>
    <dbReference type="eggNOG" id="ENOG502SGMK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_951197_0_0_1"/>
    <dbReference type="OMA" id="KLAACWI"/>
    <dbReference type="OrthoDB" id="497908at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="293" mass="31706" checksum="E07497E926A6BAF6" modified="2007-05-15" version="1" fragment="single">LYLSSILSARSKPSLARRGARARPTSSVPHTSTRRSMRAATSPRVRAALRPSTRLSRVRTSRATHTRAEPSKSEEKASKDAQDEDDAFAIDLSVDVEKEFKRGLEFGNTEVRARFRPEAISEVDRGLPIADSLVAVSAQVLVAVAALSAGNIPSWLAPIGPRWRGLAYLLPAIVHGAKLASVWVVGGLAGKAYERKAFDGTFREAMRRTVSGGCFAVGLLIFITQIEVAHKFHELGLGDPVLESSPEGDLVINGALSELLVDIFSEAGALLTWRAIRWNTSPTDPASLLEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7P8</accession>
    <name>A4S7P8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_8492</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. CGFS subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421309.1">
        <property type="nucleotide sequence ID" value="XM_001421272.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7P8"/>
    <dbReference type="STRING" id="436017.A4S7P8"/>
    <dbReference type="GeneID" id="5005466"/>
    <dbReference type="Gramene" id="ABO99602">
        <property type="protein sequence ID" value="ABO99602"/>
        <property type="gene ID" value="OSTLU_8492"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8492"/>
    <dbReference type="eggNOG" id="KOG0911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026126_2_1_1"/>
    <dbReference type="OMA" id="CAFSKRM"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014434">
        <property type="entry name" value="Monothiol_GRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005894">
        <property type="entry name" value="Monothiol_GRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="10">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="13508" checksum="2011C73684DFF120" modified="2007-05-15" version="1" fragment="single">SDTHDDFKPKVADASNEDVERAIESDVQTNAVLIYMKGSPSAPQCGFSNMACRILDHHGVEYASRNVLASEELRNGIKAYSAWPTIPQLYVKGEFVGGSDIMMSMHQSGELAELFKDVAKRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="115" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8G9</accession>
    <name>A4S8G9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="14">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_40728</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="14"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421620.1">
        <property type="nucleotide sequence ID" value="XM_001421583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8G9"/>
    <dbReference type="STRING" id="436017.A4S8G9"/>
    <dbReference type="GeneID" id="5005729"/>
    <dbReference type="Gramene" id="ABO99913">
        <property type="protein sequence ID" value="ABO99913"/>
        <property type="gene ID" value="OSTLU_40728"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40728"/>
    <dbReference type="eggNOG" id="KOG0204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_9_0_1"/>
    <dbReference type="OMA" id="HEATNIC"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="11 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="261"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="856"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="894"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="102"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="16">
        <location>
            <begin position="747"/>
            <end position="905"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO99913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="926" mass="100458" checksum="DE497CC594421558" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8W2</accession>
    <name>A4S8W2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">6-phosphofructo-2-kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_3092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421957.1">
        <property type="nucleotide sequence ID" value="XM_001421920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8W2"/>
    <dbReference type="GeneID" id="5005997"/>
    <dbReference type="Gramene" id="ABP00251">
        <property type="protein sequence ID" value="ABP00251"/>
        <property type="gene ID" value="OSTLU_3092"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3092"/>
    <dbReference type="eggNOG" id="KOG0234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006383_2_1_1"/>
    <dbReference type="OMA" id="CIQEMES"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="27820" checksum="E3628B6675F90065" modified="2007-05-15" version="1" fragment="single">EAAKESWRRRLDEYRKLYVTLQEDGSEDDLSYIKLYNYGERVQTNKMRAYLPQRIVQFLTATHPTAHKIYLCRHGESEYNVTGRLGGNSGITAKGVAFSEILRRWCETPRTVRARLWTSSLLRTIATAANIEHPTVHNGEWEQMSPRVYRNIDEIFAGDCEGMTPEEIVEKNPQAAYLRSMDKIGYRYPRGESYFDLISRLEPCIQEMESYTEPVLIVSHQAILRLIFAYLTGCARERAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9A1</accession>
    <name>A4S9A1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C3HC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_93879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422026.1">
        <property type="nucleotide sequence ID" value="XM_001421989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9A1"/>
    <dbReference type="STRING" id="436017.A4S9A1"/>
    <dbReference type="GeneID" id="5005930"/>
    <dbReference type="Gramene" id="ABP00320">
        <property type="protein sequence ID" value="ABP00320"/>
        <property type="gene ID" value="OSTLU_93879"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93879"/>
    <dbReference type="eggNOG" id="KOG4765">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_512315_0_0_1"/>
    <dbReference type="OMA" id="PWIACER"/>
    <dbReference type="OrthoDB" id="10575905at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012935">
        <property type="entry name" value="NuBaID_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835">
        <property type="entry name" value="NUCLEAR-INTERACTING PARTNER OF ALK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835:SF6">
        <property type="entry name" value="ZINC FINGER C3HC-TYPE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07967">
        <property type="entry name" value="zf-C3HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C3HC-type" evidence="4">
        <location>
            <begin position="49"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="375"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="532" mass="56695" checksum="6500D534BEAC1E08" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9E6</accession>
    <name>A4S9E6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422050.1">
        <property type="nucleotide sequence ID" value="XM_001422013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9E6"/>
    <dbReference type="GeneID" id="5005951"/>
    <dbReference type="Gramene" id="ABP00344">
        <property type="protein sequence ID" value="ABP00344"/>
        <property type="gene ID" value="OSTLU_93894"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93894"/>
    <dbReference type="HOGENOM" id="CLU_858912_0_0_1"/>
    <dbReference type="OMA" id="RWRTNIF"/>
    <dbReference type="OrthoDB" id="498752at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="36726" checksum="9C5BD4C44706EB98" modified="2007-05-15" version="1">MRRALAALAIAAELGRELAEASALDSVAARSRTVRVFEQPPEATTPTVRKNEGDDDYDYDYGYDSDGDGDGEARYAREGWYDEFARASDGVDSGARTMSYDEYVEREVAKLELSLIESASASDAGAMRETLDEIAYDIQSDLERIANARALEMTWVGDAAYPPVDFVAFTNEAYVVYDADGSRVMFEPQGEIGRLMQQLTWFSTIFPGNPTALDDYMRCATLVRPCSVEEVLRRCTYENRGSWYRERISRMNAPLSWPYCQPDLEEVYQFCTEFELQSGLCDPRRARERMYLSRTVAINGGTAPCLRWRTNIFGTRECIDRGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9M0</accession>
    <name>A4S9M0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Selenide, water dikinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_41986</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422195.1">
        <property type="nucleotide sequence ID" value="XM_001422158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9M0"/>
    <dbReference type="STRING" id="436017.A4S9M0"/>
    <dbReference type="GeneID" id="5006252"/>
    <dbReference type="Gramene" id="ABP00512">
        <property type="protein sequence ID" value="ABP00512"/>
        <property type="gene ID" value="OSTLU_41986"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41986"/>
    <dbReference type="eggNOG" id="KOG3939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019558_0_0_1"/>
    <dbReference type="OMA" id="HACSDLW"/>
    <dbReference type="OrthoDB" id="409395at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017584">
        <property type="entry name" value="Pyridine_nucleo_diS_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03169">
        <property type="entry name" value="Nterm_to_SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256:SF0">
        <property type="entry name" value="INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="SELENIDE, WATER DIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FADPNR"/>
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        <property type="entry name" value="PurM C-terminal domain-like"/>
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        <property type="entry name" value="PurM N-terminal domain-like"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0711">Selenium</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="8">
        <location>
            <begin position="12"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like N-terminal" evidence="6">
        <location>
            <begin position="461"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="7">
        <location>
            <begin position="582"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="796" mass="84023" checksum="51C7A5F2463BD1B4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9V7</accession>
    <name>A4S9V7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC6</fullName>
            <shortName evidence="6">RNA polymerase III subunit C6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_42021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABP00555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="5006295"/>
    <dbReference type="Gramene" id="ABP00555">
        <property type="protein sequence ID" value="ABP00555"/>
        <property type="gene ID" value="OSTLU_42021"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42021"/>
    <dbReference type="eggNOG" id="KOG3233">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033661_1_0_1"/>
    <dbReference type="OMA" id="VGTTKKC"/>
    <dbReference type="OrthoDB" id="613763at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC6"/>
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    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12780">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05158">
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    </dbReference>
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        <property type="entry name" value="Winged helix' DNA-binding domain"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR028763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="259" mass="29507" checksum="917DB4FD3F15D1B2" modified="2007-05-15" version="1">MSVEERAEAINTLLREKKIDVFGRGGGLVYARVREAQAAKFKGLSTEDMLVYQIIQHAGNAGMWTKELKQRSNLPVPQITKIFKTLEARKLIKSVKHVAQQNRKVYMLYELEPSREITGGAWYTEQEYDAEFISVLREQCVKFIYSRERVTLKEVSDFVRASELSRIDLGQDEVLQIVNTLVYDGKVDEIKDESQDDGMGKADEDFQPITFYTRAALPVPESNAYTDIPCGVCPVINECRPDGLINPSSCEYMTAWLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9X9</accession>
    <name>A4S9X9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422144.1">
        <property type="nucleotide sequence ID" value="XM_001422107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9X9"/>
    <dbReference type="STRING" id="436017.A4S9X9"/>
    <dbReference type="GeneID" id="5006307"/>
    <dbReference type="Gramene" id="ABP00461">
        <property type="protein sequence ID" value="ABP00461"/>
        <property type="gene ID" value="OSTLU_28352"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28352"/>
    <dbReference type="HOGENOM" id="CLU_543326_0_0_1"/>
    <dbReference type="OMA" id="ACAPMIG"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="620" mass="68917" checksum="5D49F0AF462A99A1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA58</accession>
    <name>A4SA58_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422321.1">
        <property type="nucleotide sequence ID" value="XM_001422284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA58"/>
    <dbReference type="GeneID" id="5006345"/>
    <dbReference type="Gramene" id="ABP00638">
        <property type="protein sequence ID" value="ABP00638"/>
        <property type="gene ID" value="OSTLU_28438"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28438"/>
    <dbReference type="HOGENOM" id="CLU_685853_0_0_1"/>
    <dbReference type="OrthoDB" id="9997758at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="402" mass="44191" checksum="6EAFD32C0B634D10" modified="2007-05-15" version="1">MTGKVRAGRSKRVFIAVALLGTACVVASSRERRLFSGSRRARARPGLAADVSRASGRGDGGFARATSDGGDDAFANDPREDGDDGDAPCDAPRRVREVREGAASATPTRVWDEYVLRGNDLPQTEYACEGASRREYTRFLTWKTTCVPAVKAPFIKSFLECMPDLRYVFFTDKGIAKFLDEYAKESGIEGMDEAVRKMNSSRSNHGLKLAEMSRPLLLEKFGGLAFDLDVECKKSWRPILSEFEALMVLEPGDESRGGIYQHFDSSKPDVISPLLADFSSKIDVLSSVMAAGKPHSDFFRELAAFMARTVTDAHFQVEINPVVNIGPVFHYSFLEHWFAHKPPRAKGAAVASYLLHFANCSACLGVHHGGCTWCDENFEPKGDACVDIREILPGDKLTIMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA59</accession>
    <name>A4SA59_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422290.1">
        <property type="nucleotide sequence ID" value="XM_001422253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA59"/>
    <dbReference type="STRING" id="436017.A4SA59"/>
    <dbReference type="GeneID" id="5006379"/>
    <dbReference type="Gramene" id="ABP00607">
        <property type="protein sequence ID" value="ABP00607"/>
        <property type="gene ID" value="OSTLU_18800"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18800"/>
    <dbReference type="eggNOG" id="ENOG502S4YP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1047293_0_0_1"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF13">
        <property type="entry name" value="UDP-D-APIOSE_UDP-D-XYLOSE SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="266" mass="29674" checksum="74500D8380EEE0D9" modified="2007-05-15" version="1">MRVLVLGSSGLIGAPLVARLRRAGHDVTEWDVAMDRAHDLTDAANVPGARDAIESSDFVFFLAFDVGGAKYISTPTASFIHRNSLLMANTFSLLHGKRFVFASSTMSNMDVPYGTLKRLGEHYTSVLSGISVRFWNVYGPQKYGERSHVITDFIHKLRTTGSITMMTSGAEKRQFLHTEDCARCLETIAAHYDEMPPVVDVTSFEWTTVRELAELLCDDVVARNDNRDSHTKSNEPSPFILSYWRPAISLREGIAQLLAESRTAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAA3</accession>
    <name>A4SAA3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422306.1">
        <property type="nucleotide sequence ID" value="XM_001422269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAA3"/>
    <dbReference type="GeneID" id="5006407"/>
    <dbReference type="Gramene" id="ABP00623">
        <property type="protein sequence ID" value="ABP00623"/>
        <property type="gene ID" value="OSTLU_28494"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28494"/>
    <dbReference type="HOGENOM" id="CLU_2376652_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="10723" checksum="B3E0E47EAE700E5C" modified="2007-05-15" version="1">MYEGKIMNLINVDVCRAVARHFAPRARPGGAESTDVSAYRDIRPFKFEFCAWVLTEHDRWSSMGTLTFGPDSVAYDAPSRAPKRVSDRVDGTERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAG9</accession>
    <name>A4SAG9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_3281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422386.1">
        <property type="nucleotide sequence ID" value="XM_001422349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAG9"/>
    <dbReference type="STRING" id="436017.A4SAG9"/>
    <dbReference type="GeneID" id="5006444"/>
    <dbReference type="Gramene" id="ABP00703">
        <property type="protein sequence ID" value="ABP00703"/>
        <property type="gene ID" value="OSTLU_3281"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3281"/>
    <dbReference type="HOGENOM" id="CLU_025777_2_0_1"/>
    <dbReference type="OrthoDB" id="42699at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="28089" checksum="06D832F57876272F" modified="2007-05-15" version="1" fragment="single">DWNVGDVTSMRDMFSEKEGFNADLSRWNTKSVTTMSAMFNGATSFNGDMPNWNVEKVTHMTHMFRDATSFNGDMPNWNVEAVTNMAQVFSGATSFNGDISNWNPKAVTGMYRTFYGATSFNGDISNWNVEAVKDMSQVFNGATSFNGDISNWNVEAVTSMRDMFYGATNFNGDISNWNPKAVKDMNQMFRDATSFNGDISAWNIQAVTDMSNMFNNARAFARDITGWNAAAIAAARDATKVSGMFKNATAWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAQ5</accession>
    <name>A4SAQ5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plastid-localized, cytochrome c assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CCSA</name>
        <name evidence="8" type="ORF">OSTLU_43520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422474.1">
        <property type="nucleotide sequence ID" value="XM_001422437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAQ5"/>
    <dbReference type="STRING" id="436017.A4SAQ5"/>
    <dbReference type="GeneID" id="5006532"/>
    <dbReference type="Gramene" id="ABP00791">
        <property type="protein sequence ID" value="ABP00791"/>
        <property type="gene ID" value="OSTLU_43520"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43520"/>
    <dbReference type="eggNOG" id="ENOG502QU0T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049710_2_2_1"/>
    <dbReference type="OMA" id="YESLCFL"/>
    <dbReference type="OrthoDB" id="1640at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01391">
        <property type="entry name" value="CytC_CcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017562">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03144">
        <property type="entry name" value="cytochr_II_ccsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071:SF1">
        <property type="entry name" value="CYTOCHROME B_B6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="HEME EXPORTER PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c assembly protein" evidence="7">
        <location>
            <begin position="24"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="295" mass="31740" checksum="A0C52E1FE9676408" modified="2007-05-15" version="1">MYVGNASLFGLLAARWIESGHFPLSNMYESLLFLAWGITAVHLVVTERDGFSESAIPGALAGPTAALTVAGATLALPAELQRATALVPALKSNWLMMHVSVMMLSYATLLVGSLSCVSYLVVDASQDWAAAKGALEKLDKMVSNDGERVRNRPKVSVAADGETVAVETMNASEDYGGELAIEATRDGERILTEMDNLAYRCLGAGFTLLTAGLVSGAVWANEAWGSYWSWDPKETWALITWLVYATYLHSRLVAGWSKKDSCAVGAAGFLVVWVCYVGVNLWGVGLHSYGWFANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB00</accession>
    <name>A4SB00_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CDP-alcohol phosphatidyltransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_5483</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422530.1">
        <property type="nucleotide sequence ID" value="XM_001422493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB00"/>
    <dbReference type="STRING" id="436017.A4SB00"/>
    <dbReference type="GeneID" id="5006588"/>
    <dbReference type="Gramene" id="ABP00847">
        <property type="protein sequence ID" value="ABP00847"/>
        <property type="gene ID" value="OSTLU_5483"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5483"/>
    <dbReference type="eggNOG" id="KOG1617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051314_0_2_1"/>
    <dbReference type="OMA" id="MIIYIFP"/>
    <dbReference type="OrthoDB" id="10020554at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043337">
        <property type="term" value="F:cardiolipin synthase (CMP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="19033" checksum="14517C2834ABCEDC" modified="2007-05-15" version="1" fragment="single">ERNFNAPNALCVGRIVAGPALAYGVASGASPELVLGGVAAAAFTDYLDGFLARRWKQGTILGSYLDPIADKVFVGCVGTALALEGSLPVWLVGLLVSRDAIHVVGGAWRRAGALGWKWKTVGEFLGFDDKPRGALRPLFIGKVNTALQMALITFAVSEPVFAAHAGSPMMAPALELVADRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB22</accession>
    <name>A4SB22_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_52010</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422701.1">
        <property type="nucleotide sequence ID" value="XM_001422664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB22"/>
    <dbReference type="STRING" id="436017.A4SB22"/>
    <dbReference type="GeneID" id="5006599"/>
    <dbReference type="Gramene" id="ABP01018">
        <property type="protein sequence ID" value="ABP01018"/>
        <property type="gene ID" value="OSTLU_52010"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_52010"/>
    <dbReference type="eggNOG" id="KOG0469">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_11_2_1"/>
    <dbReference type="OMA" id="ASWNTEN"/>
    <dbReference type="OrthoDB" id="203at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16268">
        <property type="entry name" value="EF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1430.10:FF:000003">
        <property type="entry name" value="Elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
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        <property type="entry name" value="EFG_III/V"/>
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    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
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        <property type="entry name" value="EFTu-like_2"/>
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        <property type="entry name" value="G_TR_CS"/>
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    <dbReference type="InterPro" id="IPR027417">
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    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
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    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
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        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
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        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="17"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="814"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP01018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="848" mass="94514" checksum="89BE6896F06589F8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBA6</accession>
    <name>A4SBA6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS8</name>
        <name evidence="6" type="ORF">OSTLU_29541</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBA6"/>
    <dbReference type="STRING" id="436017.A4SBA6"/>
    <dbReference type="GeneID" id="5006798"/>
    <dbReference type="Gramene" id="ABP00902">
        <property type="protein sequence ID" value="ABP00902"/>
        <property type="gene ID" value="OSTLU_29541"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29541"/>
    <dbReference type="eggNOG" id="KOG3283">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080597_1_1_1"/>
    <dbReference type="OMA" id="QRPHYRK"/>
    <dbReference type="OrthoDB" id="1703270at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11380">
        <property type="entry name" value="Ribosomal_S8e_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.168.20">
        <property type="entry name" value="Ribosomal protein S8e, subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_eS8"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_eS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042563">
        <property type="entry name" value="Ribosomal_protein_eS8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01193">
        <property type="entry name" value="RIBOSOMAL_S8E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="220" mass="24705" checksum="12D8415218DD3C3B" modified="2007-05-15" version="1">MGISRDSLHKRRATGGKQKPWRKKRKYELGRQPANTKLSSNVTVRQVRCRGGNIKHRALRLDTGNFAWGSENCTRKTRILDVVYNASNNELVRTKTLVKSAVIAVDAAPFRAWYAQHYGKKIGIKVKNGAKVESEDIEEKRSKSVTMKLRSRNQKHEVAKAIDEQFATGRLLAIITSRPGQCGRADGYVLEGKELEFYQKKMMKKKHAAAAAAAAKDATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBA9</accession>
    <name>A4SBA9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VEF3501</name>
        <name evidence="11" type="ORF">OSTLU_29544</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422742.1">
        <property type="nucleotide sequence ID" value="XM_001422705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBA9"/>
    <dbReference type="STRING" id="436017.A4SBA9"/>
    <dbReference type="GeneID" id="5006799"/>
    <dbReference type="Gramene" id="ABP01059">
        <property type="protein sequence ID" value="ABP01059"/>
        <property type="gene ID" value="OSTLU_29544"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29544"/>
    <dbReference type="HOGENOM" id="CLU_580607_0_0_1"/>
    <dbReference type="OMA" id="TEVAENC"/>
    <dbReference type="OrthoDB" id="166746at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21553">
        <property type="entry name" value="VEFS-box_EMF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019135">
        <property type="entry name" value="Polycomb_protein_VEFS-Box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057540">
        <property type="entry name" value="Znf_SUZ12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF0">
        <property type="entry name" value="POLYCOMB PROTEIN SUZ12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09733">
        <property type="entry name" value="VEFS-Box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23320">
        <property type="entry name" value="Zn_SUZ12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Polycomb protein SUZ12-like zinc finger" evidence="10">
        <location>
            <begin position="129"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Polycomb protein VEFS-Box" evidence="9">
        <location>
            <begin position="313"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP01059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="471" mass="53783" checksum="25F84331BE635496" modified="2007-05-15" version="1">MAPSAYTPSTSKTFDGRALRPDYKSASAGADDVDEYPVSSPVESDCFGDSESEPDARFATYTGAISVYGEFRDRRSPRQVFLRRNLSYHVERASAGSRDERGSARARGAAARERELAEKYETTYEYDRCTTRVRVRGYGCNMCKCVCVGLRGLMTHLRASHDLFRYSARREGRRAIVRIYPKGENFTADRSFVLRSQTDIQTANDKEFSFYRGKRSKREVFRERVTKAELDALYERDVRAAPPPRVVWRAVPNDDHYDRVKLEKRKRAQEEERRRIAALPFKPMVCKKNANGAASAAATKPKPKPPKKPLGPFYNSRSFVEMSEIPEQDSDDENLIPVEIMESKRFMEEFVDFSTEELSFMEAWNDVAMKFRCVADYEAPSLCEAFVRVHGDKLKVSDEFFKMFVLTLFGMYENGILNRRAVAEALGKCKSLSGASAFDRVSTSVTDREHCSVALFEKFPKFVTTLKNLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBI7</accession>
    <name>A4SBI7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422628.1">
        <property type="nucleotide sequence ID" value="XM_001422591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBI7"/>
    <dbReference type="GeneID" id="5006686"/>
    <dbReference type="Gramene" id="ABP00945">
        <property type="protein sequence ID" value="ABP00945"/>
        <property type="gene ID" value="OSTLU_25904"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25904"/>
    <dbReference type="HOGENOM" id="CLU_835079_0_0_1"/>
    <dbReference type="OMA" id="EMSDHAV"/>
    <dbReference type="OrthoDB" id="10467319at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="341" mass="36186" checksum="7A0598A9F5C46AED" modified="2007-05-15" version="1">MFKDEKRTQYSPLMTREEQAEAVNDMEDAIDEAPAARRRHVGSSSSTYTAYDNPMTSSANVDDDFESVPLRGAGRSLAQRAQAHLKSLKKTLKDAFKDAGSASRTPAPTSTYGNETYVDDASFVGSPPAGQMLSRHHARARSVDLRHVLGDLDDTLEGAHTAATLLRELRDSGGDPDADAATNDALDLELSDVCEAHRAHLTQVAEMTDSAVSLSEEQLGKLLFTLEELNAAVLSIRSDGRPKTSTTMPDPDSSCAAVPPSGPPSLGTSRIECATTEEEEAAMIAQAIAASLSVSQQSDVEKSAEDALPPPLPAPAETASTAAAPPRKQTTEELLANLIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQD0</accession>
    <name>A4RQD0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="3 10">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_48569</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 10">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="3 10"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415366.1">
        <property type="nucleotide sequence ID" value="XM_001415329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQD0"/>
    <dbReference type="STRING" id="436017.A4RQD0"/>
    <dbReference type="GeneID" id="4999538"/>
    <dbReference type="Gramene" id="ABO93658">
        <property type="protein sequence ID" value="ABO93658"/>
        <property type="gene ID" value="OSTLU_48569"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48569"/>
    <dbReference type="eggNOG" id="KOG1112">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000404_1_0_1"/>
    <dbReference type="OMA" id="IELPQHM"/>
    <dbReference type="OrthoDB" id="3000483at2759"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005971">
        <property type="term" value="C:ribonucleoside-diphosphate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009202">
        <property type="term" value="P:deoxyribonucleoside triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01679">
        <property type="entry name" value="RNR_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.70.20:FF:000010">
        <property type="entry name" value="Ribonucleoside-diphosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573:SF6">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="R1 subunit of ribonucleotide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="11">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO93658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="817" mass="91732" checksum="E5128A231D84FE60" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQM3</accession>
    <name>A4RQM3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Non-structural maintenance of chromosomes element 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_13624</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the SMC5-SMC6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NSE4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415758.1">
        <property type="nucleotide sequence ID" value="XM_001415721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQM3"/>
    <dbReference type="STRING" id="436017.A4RQM3"/>
    <dbReference type="GeneID" id="4999440"/>
    <dbReference type="Gramene" id="ABO94050">
        <property type="protein sequence ID" value="ABO94050"/>
        <property type="gene ID" value="OSTLU_13624"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13624"/>
    <dbReference type="eggNOG" id="KOG2866">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1368198_0_0_1"/>
    <dbReference type="OrthoDB" id="361242at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027786">
        <property type="entry name" value="Nse4/EID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014854">
        <property type="entry name" value="Nse4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16140">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16140:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08743">
        <property type="entry name" value="Nse4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-structural maintenance of chromosome element 4 C-terminal" evidence="9">
        <location>
            <begin position="63"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="200" mass="21949" checksum="1EAFD6821FCB45BF" modified="2007-05-15" version="1">MDTEIKERRATQRRAREALGPSVAPDEVRDTAAERQTDKMMIAMNKKLKKQPGGATDVVRGTNNPESFPQFVENVFTAAFLVKDGNAGIVPSATGGAPTLSHTTPPASGNDRSSFVLHMDMGNWRALNAMLGGTDGCMMPTREDVDEDVLYGARAKDERHEVTPKRERKRVRADDNGDTALGLHDTTNYRNVRESFSVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQX3</accession>
    <name>A4RQX3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415806.1">
        <property type="nucleotide sequence ID" value="XM_001415769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQX3"/>
    <dbReference type="GeneID" id="4999797"/>
    <dbReference type="Gramene" id="ABO94098">
        <property type="protein sequence ID" value="ABO94098"/>
        <property type="gene ID" value="OSTLU_13699"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13699"/>
    <dbReference type="HOGENOM" id="CLU_995321_0_0_1"/>
    <dbReference type="OrthoDB" id="10653176at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672942" evidence="1">
        <location>
            <begin position="33"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="280" mass="29484" checksum="7B5533DF07BF3C9D" modified="2007-05-15" version="1">MPRRRARARSSVALVALVAIVASRGGIRGANARAVANRRAGDDGTRALARAVRDGGSARDALATLVRSALAALGGGDADDARSCVDEVAEEGEKCAKALRDAAAAFSRGDASAEDAAKEFVTVGEACATKMMEIGQSCAEMTKACERELTRIEKECEEKAARLKTRCEKNELAPFECAASFAELGQACATETAAEVSKCVGEIQVVGSGETFGDDPDDCDAEARRLERQCHDDYDAIKAAIADGTLSFLDGMRKLAALGQRCAKEAMDLRKRCHPDGPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRD2</accession>
    <name>A4RRD2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase III subunit RPC4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415549.1">
        <property type="nucleotide sequence ID" value="XM_001415512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRD2"/>
    <dbReference type="STRING" id="436017.A4RRD2"/>
    <dbReference type="GeneID" id="4999591"/>
    <dbReference type="Gramene" id="ABO93841">
        <property type="protein sequence ID" value="ABO93841"/>
        <property type="gene ID" value="OSTLU_28975"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28975"/>
    <dbReference type="eggNOG" id="ENOG502RUZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1449922_0_0_1"/>
    <dbReference type="OMA" id="DMAYEED"/>
    <dbReference type="OrthoDB" id="5836119at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20837" checksum="AF8CB33208E36EB3" modified="2007-05-15" version="1">MSKAKQAQLALEEASRRIQPERATTEEMYDAEEDWTDKSQYYPTVLTRSSREVDVGAVGDTVRESTEDKYVVLQLPSDLPLRKRIASEEMDVDGVVTLRDDDPDDEDSGMVRGVSELSNGQLGELKIHADGSAKLYIGNAVFDVMRGTPYQHSEQLARLDGDRQQCVIMGPTIARMTCVPDVTQLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRI6</accession>
    <name>A4RRI6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Growth arrest-specific protein 8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_40013</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DRC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415908.1">
        <property type="nucleotide sequence ID" value="XM_001415871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRI6"/>
    <dbReference type="STRING" id="436017.A4RRI6"/>
    <dbReference type="GeneID" id="4999962"/>
    <dbReference type="Gramene" id="ABO94200">
        <property type="protein sequence ID" value="ABO94200"/>
        <property type="gene ID" value="OSTLU_40013"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40013"/>
    <dbReference type="eggNOG" id="ENOG502QQDA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045343_0_0_1"/>
    <dbReference type="OMA" id="MKHLQYE"/>
    <dbReference type="OrthoDB" id="498391at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039308">
        <property type="entry name" value="GAS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025593">
        <property type="entry name" value="GAS8_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543:SF0">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13851">
        <property type="entry name" value="GAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Growth arrest-specific protein 8" evidence="13">
        <location>
            <begin position="234"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="41"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="141"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="261"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="377" mass="44283" checksum="458F77064579E9D6" modified="2007-05-15" version="1">MPKEQVTPPKKKTGSKTDKKARPKADAADGLSGEGPIQETRAELLAKIQAVEREAVKANEHRNYMQLERDKIDSFWEITKAELESTKVDLRDAQRELEVAGEQHEMELRLQTHKLKQVKHERLEAESKVRAQYDQAEAQLREDCRDRLQIKSQELAAMEAKIREIRREHEDRRRRLKLEHDANLGAARKQFEQSASEHVNKVERESFDAMNSFKCRVEKQLADTEARYSTYIDELVETHTKAYDELKEYFNSLTDTHVVEINRLDQRLNAKEERLHKQALELNEIRKKNAALVVPLTQAEHKCEEYRKKLLHSERKCKHLQYSEKALHDIQSQLKSSKWQNEILIQKLEKSEEDLEALRHEGMSRRFCAPSFTKTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRQ8</accession>
    <name>A4RRQ8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415943.1">
        <property type="nucleotide sequence ID" value="XM_001415906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRQ8"/>
    <dbReference type="GeneID" id="4999486"/>
    <dbReference type="Gramene" id="ABO94235">
        <property type="protein sequence ID" value="ABO94235"/>
        <property type="gene ID" value="OSTLU_29104"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29104"/>
    <dbReference type="HOGENOM" id="CLU_1716293_0_0_1"/>
    <dbReference type="OMA" id="LEMEWIA"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="153" mass="17806" checksum="4EEAE86FBBAA4956" modified="2007-05-15" version="1">MKRERNEADWGERAARGGETATSEGGETWRYAETADEYEYRGAWLALHRQPGESTRDEAFEEKVRAMKAVSKRLKEANMATSDFEPGGESYENFLGEHVLRHVTLARRLSEWRTNFLIRFAREPEYADMPSTVRDLEMEWIALGFKIRAIEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRZ8</accession>
    <name>A4RRZ8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415653.1">
        <property type="nucleotide sequence ID" value="XM_001415616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRZ8"/>
    <dbReference type="GeneID" id="5000040"/>
    <dbReference type="KEGG" id="olu:OSTLU_92214"/>
    <dbReference type="HOGENOM" id="CLU_1067092_0_0_1"/>
    <dbReference type="OMA" id="CVACAAY"/>
    <dbReference type="OrthoDB" id="10268124at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="261" mass="25002" checksum="BEB10A8B4044F954" modified="2007-05-15" version="1" fragment="single">LARAAFAHASAGTATTISGFTAKSCGGTAQQYANSGASGTKTFTWTAPADLTSVSSVDISAGYAAGQGAVTRQTITLTRAPGAACATNQRVSSGACVACPAGSTRAAGDPVYGGDTTCTATLCATNERVSNNACVACAGSATNAAGDDATQSDTTCDGAACASNQHVSSSSCTACPAGTTRAAGDPVYGGDTTCTATACGANERVSNNACVACAAYTTNAAGDLANGGDTACDAASAAPAGPKFIVFALFTALACACARVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS88</accession>
    <name>A4RS88_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_14048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416035.1">
        <property type="nucleotide sequence ID" value="XM_001415998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS88"/>
    <dbReference type="GeneID" id="4999382"/>
    <dbReference type="Gramene" id="ABO94327">
        <property type="protein sequence ID" value="ABO94327"/>
        <property type="gene ID" value="OSTLU_14048"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14048"/>
    <dbReference type="HOGENOM" id="CLU_1121638_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="248" mass="26047" checksum="C7D9B855E9521421" modified="2007-05-15" version="1">MAASRSGDDDEDATTNAATHATTNATTNAASSDVDVRVPAPGEVSRLTQTASVRAREDGAEAIACLTRQGGKDAFTSVEDARDRLLAFHAYAGPEDVGWDPRWNPKPANGGNEIEGVLKLAREEAWTRDLEVFAEEASTFVGDVRAMLPKVEERLAASADGAPLDANERAFVESLLLHRAQQNARAAAIERDMVFARGAALAREINTLESQIREQSAERARVAAAPLGVDGAAPSAPAATAPTFGGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSD3</accession>
    <name>A4RSD3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416511.1">
        <property type="nucleotide sequence ID" value="XM_001416474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSD3"/>
    <dbReference type="GeneID" id="5000085"/>
    <dbReference type="Gramene" id="ABO94804">
        <property type="protein sequence ID" value="ABO94804"/>
        <property type="gene ID" value="OSTLU_30296"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30296"/>
    <dbReference type="HOGENOM" id="CLU_864333_0_0_1"/>
    <dbReference type="OMA" id="IECACES"/>
    <dbReference type="OrthoDB" id="10574155at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="322" mass="34384" checksum="7F0073F1BD14E445" modified="2007-05-15" version="1">MPMPMPTRLTKTTPTTRARHRAGRGTRARRGATSASTREDVRDIARDIATATPTSRAHSLADCAYATATTSATMRLRDRVACALAATAIEAVVASGMDPAEGGFGAEDEDFRGAESLLISLALEEAMKRNGDRREVRVRVGYALCAMTEDASEATAHAWLEIEGKVLDVCSPGMILCEAARRSGVDYDDRDAMTAQFGAEALLAAGYAPATKERPMRHRPLTVLNVAVPLGGSRGAREKTKPGYGLTLKPPPAGVRGAANAQKRVEFFQSQVLAAGVLGIEKFKDAAPPAARAAYERIVAARVETVRSREDRLERAIAPARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSR5</accession>
    <name>A4RSR5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Btf3</name>
        <name evidence="5" type="ORF">OSTLU_119600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the nascent polypeptide-associated complex (NAC).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAC-beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416199.1">
        <property type="nucleotide sequence ID" value="XM_001416162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSR5"/>
    <dbReference type="STRING" id="436017.A4RSR5"/>
    <dbReference type="GeneID" id="5000355"/>
    <dbReference type="Gramene" id="ABO94492">
        <property type="protein sequence ID" value="ABO94492"/>
        <property type="gene ID" value="OSTLU_119600"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119600"/>
    <dbReference type="eggNOG" id="KOG2240">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098726_1_0_1"/>
    <dbReference type="OMA" id="GDNKAPM"/>
    <dbReference type="OrthoDB" id="8033832at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd22055">
        <property type="entry name" value="NAC_BTF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000001">
        <property type="entry name" value="Transcription factor BTF3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039370">
        <property type="entry name" value="BTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10351">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NAC-A/B" evidence="4">
        <location>
            <begin position="33"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="124" mass="13463" checksum="9149496CA2493BE8" modified="2007-05-15" version="1">MDVDRLQRLASAVRTGGKGSMRRKKKAAHKAVSADDTKLQNCLKRMQVNTIPGIQEVNIFQGENVIQFANPKLQASPPANTYVVTGPSSTRALQDILPGVFSQLGPENIANLKKVAEQYSQESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSS7</accession>
    <name>A4RSS7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 2, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Eif2a</name>
        <name evidence="5" type="ORF">OSTLU_119592</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416440.1">
        <property type="nucleotide sequence ID" value="XM_001416403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSS7"/>
    <dbReference type="STRING" id="436017.A4RSS7"/>
    <dbReference type="GeneID" id="5000183"/>
    <dbReference type="Gramene" id="ABO94733">
        <property type="protein sequence ID" value="ABO94733"/>
        <property type="gene ID" value="OSTLU_119592"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119592"/>
    <dbReference type="eggNOG" id="KOG2916">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033458_0_1_1"/>
    <dbReference type="OMA" id="DVNEHQR"/>
    <dbReference type="OrthoDB" id="1685042at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000015">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="17"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="322" mass="36590" checksum="8C44DE45DB420640" modified="2007-05-15" version="1">MKAPECRMYAERFPEIDQVVMVQVNTLVKSIAEMGAYVQLLEYDNIEGMILLSELTRRRIRSVSKLIKVGRIEPAMVLRVDEEKGYIDLSKRRVSPEDVEACEIKFNKSKVVHSIIRHVSETTGTLPETLYKSIGWPLYRKYGHAFDAFKMFVMDSSLLHREIAEFRASGDEDNQTVDESVALTLLKDIRRRMTPQPLKIRADVELTCFQYDGVLHIKSAMRAAELVSTEDCKVKMSLVASPLYVLSTQTSEREFGISLVDKAISVLQEYITSKGGKLLIKESARVVSERDDKLLAEQITNLNKVEERGSDTDDDTMGEVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RST3</accession>
    <name>A4RST3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thylakoid lumenal 20 kDa protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Tlp20</name>
        <name evidence="3" type="ORF">OSTLU_119587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416437.1">
        <property type="nucleotide sequence ID" value="XM_001416400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RST3"/>
    <dbReference type="STRING" id="436017.A4RST3"/>
    <dbReference type="GeneID" id="5000223"/>
    <dbReference type="Gramene" id="ABO94730">
        <property type="protein sequence ID" value="ABO94730"/>
        <property type="gene ID" value="OSTLU_119587"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119587"/>
    <dbReference type="eggNOG" id="ENOG502QT2I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061284_0_0_1"/>
    <dbReference type="OMA" id="ANDKQWA"/>
    <dbReference type="OrthoDB" id="512438at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF16">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="2">
        <location>
            <begin position="118"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="285" mass="30920" checksum="1AEED104DC3FB89E" modified="2007-05-15" version="1">MIISITASRARGIKNEANQRFAKSRPDRGRGISSKYKKHTGGSSLITKCKTCAATRREFNGIALSGVFSILHTGSVEAFEDGKQVSAYLPASVDVSGYFVFEAGQTRTPALRAGAIEPYKISLPGDWKEIPVSNAKSGNYCQPRCDEATTEVQFASPTAGTLQVIIIPTNKLMITEKSPEIESVGTLDSVLNAVSPAITGSVAVEQEEIISQEQYSKNNRGYYQYELLTPFAAYGLHNLACVTTSQNYVVIATVAASEKQWSTSEQELRNVVTSFQISKVSQKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSW0</accession>
    <name>A4RSW0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CycA</name>
        <name evidence="7" type="ORF">OSTLU_119556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416424.1">
        <property type="nucleotide sequence ID" value="XM_001416387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSW0"/>
    <dbReference type="STRING" id="436017.A4RSW0"/>
    <dbReference type="GeneID" id="5000199"/>
    <dbReference type="Gramene" id="ABO94717">
        <property type="protein sequence ID" value="ABO94717"/>
        <property type="gene ID" value="OSTLU_119556"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119556"/>
    <dbReference type="eggNOG" id="KOG0654">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020695_2_4_1"/>
    <dbReference type="OMA" id="HVVRANT"/>
    <dbReference type="OrthoDB" id="498396at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="114"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="6">
        <location>
            <begin position="207"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="211"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="37129" checksum="652AB9F6C8C7C9D9" modified="2007-05-15" version="1">MVPGVVDESGHLTILRDVTNSSTNRFLLKESSKLAGSAPSTSASEDQVHKSASQGYAKDVSAASLTGNNVRMSNKFSTVDDIYINLLKSQREPPSKLGLSSPDISMSMRRILVDWMIEVAEEYKLVPETLFLSVAYTDMCLQQLPISRSKLQLLGITCVFIAAKYEEIYAPQIEELCFITDNSYDRSQIIEMERIILKCLDFSVTLTTTKTFLTIYLSKIKADQLCSHLASFLSEVTLMRSVFLQFPPAVIAAAATVLAEFYLCREKPQIIPFLVDLDTPKLRQCIDILHADMMAYEPDQFQAIHEKYSEHKYAQVTSIVPRVDPLNVLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSW9</accession>
    <name>A4RSW9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arogenate dehydrogenase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ardh</name>
        <name evidence="3" type="ORF">OSTLU_119548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416172.1">
        <property type="nucleotide sequence ID" value="XM_001416135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSW9"/>
    <dbReference type="STRING" id="436017.A4RSW9"/>
    <dbReference type="GeneID" id="5000437"/>
    <dbReference type="Gramene" id="ABO94465">
        <property type="protein sequence ID" value="ABO94465"/>
        <property type="gene ID" value="OSTLU_119548"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119548"/>
    <dbReference type="eggNOG" id="KOG2380">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036672_0_1_1"/>
    <dbReference type="OMA" id="CLHPMFG"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033730">
        <property type="term" value="F:arogenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012070">
        <property type="entry name" value="Arogenate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045011">
        <property type="entry name" value="TYRAAT1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059064">
        <property type="entry name" value="TYRAAT2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43207:SF4">
        <property type="entry name" value="AROGENATE DEHYDROGENASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43207">
        <property type="entry name" value="AROGENATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26213">
        <property type="entry name" value="TYRAAT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036577">
        <property type="entry name" value="PDH_ADH_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="2">
        <location>
            <begin position="56"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="321" mass="36711" checksum="A4A7751460C49893" modified="2007-05-15" version="1">MIVRCHGPPASRVFSRLGRIRTARTRTALKGVRALDAAQPFDGENKQRMREHKIKLKIGIIGFGNFGQFLSKHFVDQGHTVIATSRGNYSDIAKDLRVRFYRDADDFCEEHPDVVVVCTSILSTDATLRNFPLQRLKRSTLFCDVLSVKQFPKQLFQQLLPPDFDILCLHPMFGPDSGKHGWRDLPLVFDKVRIGTEPCREERCARLLGIFEAAGCRMVEMSCEEHDRQAASSQFITHTVGRMLGTMELTETTISTKGFESLLSLVDNTYNDSFELYYGLFMYNKNATAELSRLELAFTKVKGELFDRLHERIRNDIFEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSZ5</accession>
    <name>A4RSZ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="12">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">Acr2</name>
        <name evidence="19" type="ORF">OSTLU_119522</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="12"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416405.1">
        <property type="nucleotide sequence ID" value="XM_001416368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSZ5"/>
    <dbReference type="STRING" id="436017.A4RSZ5"/>
    <dbReference type="GeneID" id="5000475"/>
    <dbReference type="Gramene" id="ABO94698">
        <property type="protein sequence ID" value="ABO94698"/>
        <property type="gene ID" value="OSTLU_119522"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119522"/>
    <dbReference type="eggNOG" id="KOG0216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="OMA" id="FFGVVHY"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009674">
        <property type="entry name" value="Rpa2_dom_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06883">
        <property type="entry name" value="RNA_pol_Rpa2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12 19" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="16">
        <location>
            <begin position="39"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="216"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="462"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="18">
        <location>
            <begin position="573"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="13">
        <location>
            <begin position="680"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="14">
        <location>
            <begin position="1044"/>
            <end position="1143"/>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416330.1">
        <property type="nucleotide sequence ID" value="XM_001416293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTD3"/>
    <dbReference type="GeneID" id="5000541"/>
    <dbReference type="Gramene" id="ABO94623">
        <property type="protein sequence ID" value="ABO94623"/>
        <property type="gene ID" value="OSTLU_14132"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14132"/>
    <dbReference type="HOGENOM" id="CLU_480086_0_0_1"/>
    <dbReference type="OMA" id="DNAFARN"/>
    <dbReference type="OrthoDB" id="10523431at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="666" mass="73005" checksum="6913F5167A8917E3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTG8</accession>
    <name>A4RTG8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_36086</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family. Importin beta-1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416317.1">
        <property type="nucleotide sequence ID" value="XM_001416280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTG8"/>
    <dbReference type="STRING" id="436017.A4RTG8"/>
    <dbReference type="GeneID" id="5000228"/>
    <dbReference type="Gramene" id="ABO94610">
        <property type="protein sequence ID" value="ABO94610"/>
        <property type="gene ID" value="OSTLU_36086"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36086"/>
    <dbReference type="eggNOG" id="KOG1241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008296_0_0_1"/>
    <dbReference type="OMA" id="QQYQERW"/>
    <dbReference type="OrthoDB" id="10263328at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000027">
        <property type="entry name" value="Importin subunit beta-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="873" mass="95260" checksum="F89B481BF7ED7E01" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTU9</accession>
    <name>A4RTU9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_14452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416847.1">
        <property type="nucleotide sequence ID" value="XM_001416810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTU9"/>
    <dbReference type="STRING" id="436017.A4RTU9"/>
    <dbReference type="GeneID" id="5000800"/>
    <dbReference type="Gramene" id="ABO95140">
        <property type="protein sequence ID" value="ABO95140"/>
        <property type="gene ID" value="OSTLU_14452"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14452"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_941324_0_0_1"/>
    <dbReference type="OMA" id="AGWWAVM"/>
    <dbReference type="OrthoDB" id="531840at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="3">
        <location>
            <begin position="39"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="31524" checksum="A39EB2DE78026CA7" modified="2007-05-15" version="1">MADALPSECLMFDRGVKAVRSRGSNAEIEFENGDREVFDLVIGADGIDSRAREAVDGGESPPKYSGIRIVFGCTPAGSTARAASEMNIAHQWFADGAYMLVFTGGGEGAQNKQHNIALCVQDKTKRDENTAWRAKAAAKEEAVALMREKGMPQSAIDVAEACDRFFDVGVHYHDVLDSWSDDAGTISLVGDACHAMPPFLGQGANQAMQDALCIASELSKVGAEYDTVKQALRAYEGIRKPPTAAIMQSSRFIGALETGAGPVSLFRDVAFFMAGTLGITGKVFLSGALPRFEGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU88</accession>
    <name>A4RU88_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416629.1">
        <property type="nucleotide sequence ID" value="XM_001416592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU88"/>
    <dbReference type="STRING" id="436017.A4RU88"/>
    <dbReference type="GeneID" id="5000734"/>
    <dbReference type="Gramene" id="ABO94922">
        <property type="protein sequence ID" value="ABO94922"/>
        <property type="gene ID" value="OSTLU_14565"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14565"/>
    <dbReference type="eggNOG" id="ENOG502QQTD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060640_1_0_1"/>
    <dbReference type="OMA" id="KDMKRGH"/>
    <dbReference type="OrthoDB" id="1914410at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053284">
        <property type="entry name" value="RGS1-HXK1_interactor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34554">
        <property type="entry name" value="RGS1-HXK1-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34554:SF2">
        <property type="entry name" value="RGS1-HXK1-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="164" mass="17620" checksum="08D03B5C80FE461F" modified="2007-05-15" version="1">MASKRVVETVRENPASATAGALTFLALALPGPRALLWRSTLGRLQSEEALFNACVRRSETLALDAEAASGEIQRLTEAASAAEVEMKRGAANLKSAARELRAMESRTYGMDKKATTLLNDLRVLPSKEAVALQEQVASTVDKVAAHRNVALSTLKRIFKSGIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUJ6</accession>
    <name>A4RUJ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-amylase</fullName>
            <ecNumber evidence="6">3.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_14648</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Hydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 14 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.2" evidence="6"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416970.1">
        <property type="nucleotide sequence ID" value="XM_001416933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUJ6"/>
    <dbReference type="STRING" id="436017.A4RUJ6"/>
    <dbReference type="CAZy" id="GH14">
        <property type="family name" value="Glycoside Hydrolase Family 14"/>
    </dbReference>
    <dbReference type="GeneID" id="5000608"/>
    <dbReference type="Gramene" id="ABO95263">
        <property type="protein sequence ID" value="ABO95263"/>
        <property type="gene ID" value="OSTLU_14648"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14648"/>
    <dbReference type="eggNOG" id="ENOG502QTBX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016754_5_1_1"/>
    <dbReference type="OMA" id="CISLWAD"/>
    <dbReference type="OrthoDB" id="1660156at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016161">
        <property type="term" value="F:beta-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001554">
        <property type="entry name" value="Glyco_hydro_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31352">
        <property type="entry name" value="BETA-AMYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31352:SF31">
        <property type="entry name" value="BETA-AMYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01373">
        <property type="entry name" value="Glyco_hydro_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00750">
        <property type="entry name" value="BETAAMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="379"/>
            <end position="380"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601554-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601554-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="480" mass="54059" checksum="196F130E8336DEEC" modified="2007-05-15" version="1">MLPLNVVTNDGEVNDPEALERGLRALSEIGVEGVMIDVWWGIVERDGPRKYDWAAYREVIDMIKDAGLKVQAVMSFHACGANVGDVVEIPLPDWVLEAGKKDPDLFFTDQYGYRNPECISLWADNAATLAGRTPMNTYKDFMISFRNTFKAELGTTLTEIAVGCGPCGELRYPAYPENRFAQKASQWRFPGIGEFQCYDQRSLLSLSRAASEAGHIEWGGSGPHDTGGYNNLPFETGFFRYDGGSWDSEYGSFFLSWYSSELVNHGDRMLEMTKRVFDKRGVTLAIKCAGVHWWYNVRSHAAELTAGYFNTRAGEFVSERDGYAPIVRVCKKHGARLNFTCVEMHDSDHPWYCYCGPEGLLRQIRSACARFDVPFAGENALCRFDQAAYDKIIKNCAGEGNDEEMWREGTMLPPMACFTFLRFNAELFSPFAFESFRIFVQRMRDETGLLDTSIGNTSDEEASTEDVDEISSESRVQLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUL2</accession>
    <name>A4RUL2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_14660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416691.1">
        <property type="nucleotide sequence ID" value="XM_001416654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUL2"/>
    <dbReference type="STRING" id="436017.A4RUL2"/>
    <dbReference type="GeneID" id="5000786"/>
    <dbReference type="Gramene" id="ABO94984">
        <property type="protein sequence ID" value="ABO94984"/>
        <property type="gene ID" value="OSTLU_14660"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14660"/>
    <dbReference type="eggNOG" id="KOG0881">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_1"/>
    <dbReference type="OMA" id="ELYNDHA"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="178" mass="19597" checksum="15941A8B6EF7D44D" modified="2007-05-15" version="1">MPAVDDPKWRDDERKGAPVVTLHTTHGDVTVELYYKHAPRTCENFFELAKRGYYDGTIFHRVIAEFVIQGGDPTGTGRGGESAFGGTFEDEISRGLRHVGAGILVMANSGPNTNKSQFFITLAATPWLDGKHAIFGRVESGMHAVRAIGAVKVDKNDRPTKEVKIVGVTCDDRGFKWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUL3</accession>
    <name>A4RUL3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-soluble NSF attachment protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-ethylmaleimide-sensitive factor attachment protein gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_30660</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416979.1">
        <property type="nucleotide sequence ID" value="XM_001416942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUL3"/>
    <dbReference type="STRING" id="436017.A4RUL3"/>
    <dbReference type="GeneID" id="5000666"/>
    <dbReference type="Gramene" id="ABO95272">
        <property type="protein sequence ID" value="ABO95272"/>
        <property type="gene ID" value="OSTLU_30660"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30660"/>
    <dbReference type="eggNOG" id="KOG1585">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063974_1_0_1"/>
    <dbReference type="OMA" id="ANRACCL"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF2">
        <property type="entry name" value="GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="309" mass="33961" checksum="F46E662E5481E112" modified="2007-05-15" version="1">MSNTNEIYAKNLMKRADARMKPSLMRWKPNYDEAIELYEDAARAYRASNNFKMACEAEEKSADANVRLDNYWHAGKALERATELLTKCEPLDGGAVLQMAERANDAYVMANRTQVGAESLSRAARLLETSDTKTSAALLMLCVENLQEDGKDVYASDHHKQLGATLVRAERYQDAAEACVKYGASCARAGQMNSLAKAYLSAIIALLYDGDGVGAQATFNDVHELPGFDKSEERETAYRLLTAYRAADADKIKYAIEDSSCARFLDIVFSRLARKLPNPKHELGAVATKMGADLPTGDTTDEDAGDDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUR4</accession>
    <name>A4RUR4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_30712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416716.1">
        <property type="nucleotide sequence ID" value="XM_001416679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUR4"/>
    <dbReference type="STRING" id="436017.A4RUR4"/>
    <dbReference type="GeneID" id="5000974"/>
    <dbReference type="Gramene" id="ABO95009">
        <property type="protein sequence ID" value="ABO95009"/>
        <property type="gene ID" value="OSTLU_30712"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30712"/>
    <dbReference type="eggNOG" id="KOG2771">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013817_2_1_1"/>
    <dbReference type="OMA" id="QHWPTSF"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="346" mass="37138" checksum="FBE41770891EF915" modified="2007-05-15" version="1">MPARTSLDARAPRGIPAKAPRDADAALPTRRCVVATGIPARATSAVLASARAAAPLPASLAHVKRARASARTKGTTEVVVKLASEGASASARGDAESDAAVRADVLERHADVIASVVYADVPAEGPEDRETWEKACAIWPVSLTAPAERETETPSDEEAAYFRKWTKQACEGAKMSGNCAIIVDPARDVEIARGVDESATHPLRHAVIAAVDLAAKRDVAMYPEKEHVEALIEARRMEKLERDALEIAGVGDDAKKRKREVQTKGSAMTEIMGRPYLCTGYDVFLAREPCIMCAMGLVHSRLKRVVFAVCDNINGALSGPSGIRRLHGVRSLNHHYSVFSFDAEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVJ7</accession>
    <name>A4RVJ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">OSTLU_45404</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the type II pantothenate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417152.1">
        <property type="nucleotide sequence ID" value="XM_001417115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVJ7"/>
    <dbReference type="STRING" id="436017.A4RVJ7"/>
    <dbReference type="GeneID" id="5001154"/>
    <dbReference type="Gramene" id="ABO95445">
        <property type="protein sequence ID" value="ABO95445"/>
        <property type="gene ID" value="OSTLU_45404"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45404"/>
    <dbReference type="eggNOG" id="KOG2201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4584">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012496_0_0_1"/>
    <dbReference type="OMA" id="LNEYKYW"/>
    <dbReference type="OrthoDB" id="498611at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24123">
        <property type="entry name" value="ASKHA_NBD_PanK-II_Pank4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="pantothenate kinase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.510">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.285.20">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10880">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036075">
        <property type="entry name" value="ARMT-1-like_metal-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002791">
        <property type="entry name" value="ARMT1-like_metal-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035073">
        <property type="entry name" value="At2g17340_3_helix_bundle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00555">
        <property type="entry name" value="panK_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280:SF20">
        <property type="entry name" value="4'-PHOSPHOPANTETHEINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PANTOTHENATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01937">
        <property type="entry name" value="ARMT1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111321">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="16" id="KW-0464">Manganese</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0533">Nickel</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="19">
        <location>
            <begin position="483"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="350"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABO95445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="772" mass="85051" checksum="4B93B93EFA208D53" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVL9</accession>
    <name>A4RVL9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417440.1">
        <property type="nucleotide sequence ID" value="XM_001417403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVL9"/>
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    <dbReference type="Gramene" id="ABO95733">
        <property type="protein sequence ID" value="ABO95733"/>
        <property type="gene ID" value="OSTLU_14922"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14922"/>
    <dbReference type="HOGENOM" id="CLU_295009_0_0_1"/>
    <dbReference type="OMA" id="WKQDVEY"/>
    <dbReference type="OrthoDB" id="3549872at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
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    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1160">
        <property type="entry name" value="Vasodilator-stimulated phosphoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="243"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="614"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="680"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="862"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1027" mass="116088" checksum="895B461C711D490C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWV8</accession>
    <name>A4RWV8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417891.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWV8"/>
    <dbReference type="STRING" id="436017.A4RWV8"/>
    <dbReference type="GeneID" id="5002057"/>
    <dbReference type="Gramene" id="ABO96184">
        <property type="protein sequence ID" value="ABO96184"/>
        <property type="gene ID" value="OSTLU_24489"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24489"/>
    <dbReference type="eggNOG" id="KOG2273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037065_0_0_1"/>
    <dbReference type="OMA" id="KHIEYKV"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06859">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="55"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="357" mass="39353" checksum="A1212B3E7AEA8678" modified="2007-05-15" version="1">MTTPTTTTTAASDERAAFLTPGPRPTTPSDVGAIRVPTGYATRASADADDDDDDAGLVIEIGDPHRVGDGLSKHIEYKVTYWTDSATYGGKDSSGCSTRRFSDFEWLSKQLGANCDGVIIPLLPSKTILHMDDPSSRGIERRRKGLAAFMARCAAHPLVRKSADLHAFLTQDSKSWTQRVPWYERGVLSEGVSSVTSWLSTLNTSDMKSLTSSMSVDVMREKQQHVDVVEYVTKLKLRLEKLIAATSALQKHGAHTVSAYEEFNACLELLAGQEEKARSVFAQSGAKGVWWQRLSDLFTALIPPQRQASELMSSEFLDSLNEVHALCTAVVAAFDARKRVVDHYNKSLGRREKKNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWW3</accession>
    <name>A4RWW3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_31479</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad17/RAD24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417646.1">
        <property type="nucleotide sequence ID" value="XM_001417609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWW3"/>
    <dbReference type="STRING" id="436017.A4RWW3"/>
    <dbReference type="GeneID" id="5002156"/>
    <dbReference type="Gramene" id="ABO95939">
        <property type="protein sequence ID" value="ABO95939"/>
        <property type="gene ID" value="OSTLU_31479"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31479"/>
    <dbReference type="eggNOG" id="KOG1970">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018598_2_0_1"/>
    <dbReference type="OMA" id="YNCLKMA"/>
    <dbReference type="OrthoDB" id="552695at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004582">
        <property type="entry name" value="Checkpoint_prot_Rad17_Rad24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03215">
        <property type="entry name" value="Rad17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="574"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="578"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="593" mass="62631" checksum="62DE19EC5363F3AF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX88</accession>
    <name>A4RX88_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417711.1">
        <property type="nucleotide sequence ID" value="XM_001417674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX88"/>
    <dbReference type="STRING" id="436017.A4RX88"/>
    <dbReference type="GeneID" id="5001693"/>
    <dbReference type="Gramene" id="ABO96004">
        <property type="protein sequence ID" value="ABO96004"/>
        <property type="gene ID" value="OSTLU_31607"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31607"/>
    <dbReference type="HOGENOM" id="CLU_971109_0_0_1"/>
    <dbReference type="OrthoDB" id="76516at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044588">
        <property type="entry name" value="EREX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46856">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN EREL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46856:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN EREL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="287" mass="31567" checksum="F15F540D26146B10" modified="2007-05-15" version="1">MTPESTSVRKMDAVTPEMVTNPSAILSSPESEASPYEPRRRAIEESEAAAATAVDALNATNEEMRSLREELEATRECLKDARATAAAAEEKFSDFEVTSRKEKKVLSKEIRSLRRQLEAAKLDKNEQANIISAEDRTAVLRDVMHEVSVLRNRVQECTYEKLLSVEASSPHGHAGGDPNELLAVSDNRLAVLLAETQIMILGGEDAQPSISDSPESAEAEQELLNAERETRQTFADLLSDLINTRKSINSLLRKHFARKNEPASTTGLSSRVTNLVGAIEKKLTIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY21</accession>
    <name>A4RY21_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biogenesis of lysosome-related organelles complex 1 subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_9263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLOC1S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417853.1">
        <property type="nucleotide sequence ID" value="XM_001417816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY21"/>
    <dbReference type="STRING" id="436017.A4RY21"/>
    <dbReference type="GeneID" id="5002008"/>
    <dbReference type="Gramene" id="ABO96146">
        <property type="protein sequence ID" value="ABO96146"/>
        <property type="gene ID" value="OSTLU_9263"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9263"/>
    <dbReference type="eggNOG" id="KOG3390">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115602_2_1_1"/>
    <dbReference type="OMA" id="WMKIMEY"/>
    <dbReference type="OrthoDB" id="20018at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009395">
        <property type="entry name" value="BLOC1S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13073:SF0">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13073">
        <property type="entry name" value="BLOC-1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06320">
        <property type="entry name" value="GCN5L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="90" mass="9985" checksum="91B7DD8FA75EF792" modified="2007-05-15" version="1" fragment="single">RKETVAQVSALADAMTDSVNHGVVEVFENQKQVESSARALNETATAFRERSSEWATSLEAFDKELRDIGDFENWVKAMEHDLATLAAALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY75</accession>
    <name>A4RY75_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418120.1">
        <property type="nucleotide sequence ID" value="XM_001418083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY75"/>
    <dbReference type="GeneID" id="5001947"/>
    <dbReference type="Gramene" id="ABO96413">
        <property type="protein sequence ID" value="ABO96413"/>
        <property type="gene ID" value="OSTLU_31929"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31929"/>
    <dbReference type="HOGENOM" id="CLU_1858619_0_0_1"/>
    <dbReference type="OMA" id="KRMLEMR"/>
    <dbReference type="OrthoDB" id="495496at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="138" mass="15562" checksum="DAB4625C4218B662" modified="2007-05-15" version="1">MTAFFALTGVAVGATVLSQKAIEKNLEREIALAKANGIELDDLYYDFDLPGDAYPFGDAEGMDWVPKDWKPPKKGDARFLPSRMLGNVQLRNKMHDLSKRCSEKGIDISDLSVPFDAYEGEFDTNQKRMLEMRKRLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYA8</accession>
    <name>A4RYA8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-rhamnose mutarotase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_40891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418354.1">
        <property type="nucleotide sequence ID" value="XM_001418317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYA8"/>
    <dbReference type="STRING" id="436017.A4RYA8"/>
    <dbReference type="GeneID" id="5002249"/>
    <dbReference type="Gramene" id="ABO96647">
        <property type="protein sequence ID" value="ABO96647"/>
        <property type="gene ID" value="OSTLU_40891"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40891"/>
    <dbReference type="HOGENOM" id="CLU_100689_4_0_1"/>
    <dbReference type="OMA" id="LMWKYQQ"/>
    <dbReference type="OrthoDB" id="9981546at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016857">
        <property type="term" value="F:racemase and epimerase activity, acting on carbohydrates and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052996">
        <property type="entry name" value="Carb_Metab_Mutarotase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008000">
        <property type="entry name" value="Rham/fucose_mutarotase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43239">
        <property type="entry name" value="UPF0734 PROTEIN DDB_G0273871/DDB_G0273177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43239:SF1">
        <property type="entry name" value="UPF0734 PROTEIN DDB_G0273871_DDB_G0273177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05336">
        <property type="entry name" value="rhaM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14581" checksum="2358019E69959F3D" modified="2007-05-15" version="1" fragment="single">DATRMKTFAQTIELESEDAIEAYDALHARAWPEILESLRAVGVVDMFIYRSGVRLFMHMTTVDAFDPDVDFARHMAMSERCVEWGEVTRALQRPAPEAKVGEWWTRCRRVFDLRSQLDALDASRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYC2</accession>
    <name>A4RYC2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418361.1">
        <property type="nucleotide sequence ID" value="XM_001418324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYC2"/>
    <dbReference type="GeneID" id="5002238"/>
    <dbReference type="Gramene" id="ABO96654">
        <property type="protein sequence ID" value="ABO96654"/>
        <property type="gene ID" value="OSTLU_31975"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31975"/>
    <dbReference type="HOGENOM" id="CLU_2430996_0_0_1"/>
    <dbReference type="OrthoDB" id="544997at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="91" mass="10290" checksum="DE25D20C58CB8C9A" modified="2007-05-15" version="1">MRAKDFPFVDDALTSRAATLRDFLTSDAPRGDARARLREELVRWHPDKFSKYLDLAREEDLGEIRDRVNATSRAVRDAFKASAAAAAARPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYS3</accession>
    <name>A4RYS3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_94496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418213.1">
        <property type="nucleotide sequence ID" value="XM_001418176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYS3"/>
    <dbReference type="GeneID" id="5002308"/>
    <dbReference type="Gramene" id="ABO96506">
        <property type="protein sequence ID" value="ABO96506"/>
        <property type="gene ID" value="OSTLU_94496"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94496"/>
    <dbReference type="HOGENOM" id="CLU_2504524_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="86" mass="9251" checksum="5873429831FA65C4" modified="2007-05-15" version="1" fragment="single">MADEDMEALERMMAAMEAKEREAVDDHVTSRFPKMRIAWEANAIEGGADAVVVAGCAPIDVGGGRMKEFAGHAFHELARMKSGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYV4</accession>
    <name>A4RYV4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418228.1">
        <property type="nucleotide sequence ID" value="XM_001418191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYV4"/>
    <dbReference type="STRING" id="436017.A4RYV4"/>
    <dbReference type="GeneID" id="5002408"/>
    <dbReference type="Gramene" id="ABO96521">
        <property type="protein sequence ID" value="ABO96521"/>
        <property type="gene ID" value="OSTLU_32157"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32157"/>
    <dbReference type="HOGENOM" id="CLU_2175250_0_0_1"/>
    <dbReference type="OrthoDB" id="534691at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="110" mass="11859" checksum="EF07FE1D813079BD" modified="2007-05-15" version="1">MSVKSCVNVVPASRQGPRGPPEALRPSACAEAEALGEIREQRDMLKACAPACKASCSRAIAEYDEGQRKTTGFGLDAKAKERVLKACVVTCGKDCEKAGKSYDYIIPFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYY0</accession>
    <name>A4RYY0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_19561</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418241.1">
        <property type="nucleotide sequence ID" value="XM_001418204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYY0"/>
    <dbReference type="STRING" id="436017.A4RYY0"/>
    <dbReference type="GeneID" id="5002491"/>
    <dbReference type="Gramene" id="ABO96534">
        <property type="protein sequence ID" value="ABO96534"/>
        <property type="gene ID" value="OSTLU_19561"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19561"/>
    <dbReference type="eggNOG" id="KOG4163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_4_1_1"/>
    <dbReference type="OMA" id="WCDEVDV"/>
    <dbReference type="OrthoDB" id="1350766at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.30:FF:000001">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000007">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000005">
        <property type="entry name" value="bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="76"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="524" mass="59525" checksum="BF89035D9B8E66B9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYY2</accession>
    <name>A4RYY2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5'-3' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_5068</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418242.1">
        <property type="nucleotide sequence ID" value="XM_001418205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYY2"/>
    <dbReference type="STRING" id="436017.A4RYY2"/>
    <dbReference type="GeneID" id="5002340"/>
    <dbReference type="Gramene" id="ABO96535">
        <property type="protein sequence ID" value="ABO96535"/>
        <property type="gene ID" value="OSTLU_5068"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5068"/>
    <dbReference type="eggNOG" id="ENOG502QSF6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004675_1_0_1"/>
    <dbReference type="OMA" id="WRVDLIP"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09859">
        <property type="entry name" value="PIN_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000003">
        <property type="entry name" value="DNA polymerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646:SF2">
        <property type="entry name" value="5'-3' EXONUCLEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="FLAP ENDONUCLEASE XNI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-3' exonuclease" evidence="4">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="233" mass="25479" checksum="51DE2233C4B6CA5B" modified="2007-05-15" version="1" fragment="single">LILVDGLSFVFRAYYGWNARGSGEGLTNSAGEDTSVLYSYAHTICSLLELKPTHLAVCMDAKGKTFRHEMFVEYKANRPPTPEPLLELIPKVEQLVRDMGVPLLRLSGVEADDIIGTVSRRASDAGFRVSICSPDKDFYQLLGPKTKMLKPSKSSKGDPFDPFTVDDFRAMHNNVIEPEQFIDFLALVGDSADNIPGVEGVGPKTALALLEQYGDIESALANAANVKGKRARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ97</accession>
    <name>A4RZ97_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DMT3501</name>
        <name evidence="6" type="ORF">OSTLU_87597</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418536.1">
        <property type="nucleotide sequence ID" value="XM_001418499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ97"/>
    <dbReference type="GeneID" id="5002429"/>
    <dbReference type="Gramene" id="ABO96829">
        <property type="protein sequence ID" value="ABO96829"/>
        <property type="gene ID" value="OSTLU_87597"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87597"/>
    <dbReference type="eggNOG" id="KOG0919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049101_0_0_1"/>
    <dbReference type="OMA" id="NSLNCWV"/>
    <dbReference type="OrthoDB" id="414133at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050750">
        <property type="entry name" value="C5-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098:SF1">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="371" mass="41510" checksum="F3B4CD54FFE30B62" modified="2007-05-15" version="1">MTKRTRARDDEDDGTRDGATARTRRGGKLRVLEMYCGVGVMHAALRRARGDEAEVCGAYDVNPNACDAYAMNYGTRPSQKSLVSVAMETLVKTKAEAWAMSPPCQPFTRAGLKLDVDDGRAESFMRLVDEMVKMDASARPKYVFVENVVGFETSRMRDALRDALSASAFHAQEFILTPTMFGVPYSRPRYFMLARSTRAFEDGVDEIRRSPPPSKLSHRREWIPDFDDVRDADVVVAPLSRFLDRATDDIWRANAVKQDDVDRAKGSIDIVTAEDTTCNCFTKSYYKYVKGTGSVVANQSVDKATWDGRMGDGASDVRLRYFTVDEVARLHSLPNDFAWPSNLTTRQKYTLLGNSMSVACVAPLLDYLFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZE8</accession>
    <name>A4RZE8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YggT family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_41246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418318.1">
        <property type="nucleotide sequence ID" value="XM_001418281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZE8"/>
    <dbReference type="STRING" id="436017.A4RZE8"/>
    <dbReference type="GeneID" id="5002453"/>
    <dbReference type="Gramene" id="ABO96611">
        <property type="protein sequence ID" value="ABO96611"/>
        <property type="gene ID" value="OSTLU_41246"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41246"/>
    <dbReference type="eggNOG" id="ENOG502SA6E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136788_4_0_1"/>
    <dbReference type="OMA" id="TFMIITR"/>
    <dbReference type="OrthoDB" id="2066at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010020">
        <property type="term" value="P:chloroplast fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219:SF14">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="YLMG HOMOLOG PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="CCB3_YggT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10622" checksum="9D682154FBD19CDC" modified="2007-05-15" version="1">MIQLVTQSVASFIKLYLLLLFVRVLLTWFPNVNWMRQPWTMLRQVTDPYLNLFRNLIPPVMGQIDFTPILGFMVLQFLARVLSADSGMGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZG6</accession>
    <name>A4RZG6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418330.1">
        <property type="nucleotide sequence ID" value="XM_001418293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZG6"/>
    <dbReference type="STRING" id="436017.A4RZG6"/>
    <dbReference type="GeneID" id="5002459"/>
    <dbReference type="Gramene" id="ABO96623">
        <property type="protein sequence ID" value="ABO96623"/>
        <property type="gene ID" value="OSTLU_15935"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15935"/>
    <dbReference type="eggNOG" id="ENOG502QQ86">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_699054_0_0_1"/>
    <dbReference type="OMA" id="GASECAT"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45296">
        <property type="entry name" value="TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45296:SF1">
        <property type="entry name" value="TRANSDUCIN_WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="310"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="395" mass="42062" checksum="4DE90A6BE8F94591" modified="2007-05-15" version="1">MTLEPLEPRRAPAVADTDALVALAHRARSGNECTCATGRGTIVNFDLREPNDARAFVVRGARRREVNALTWRNEHALFHASDAVVVELDARKMSAAGDAAVIRRFEGAGDVVNGVDVDQDDAMLAACDDAGEVIAYDLSNGEILRKLRGHDGCVTAVAFRRKRGASECATASTDCRAMKWDVKAKSVPVRTWDARNVLSAEDYDCGKITARAEDESASIDAGASAKAFNPPMLHSLAFYRGETSEENAPGLRRVAVSACGDGSVIVFDIDHPGVSGGSRASKGKKKSSLASAGPFADGRVECVRLGADGVRGHTNAATCADFVPWNRTGDVIVSGGADRRLLVWNWVDEASHAARGLPVASIERDRKINDLAFAADSRAICVADTSPTLKLFALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZL9</accession>
    <name>A4RZL9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UmuC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_15984</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418818.1">
        <property type="nucleotide sequence ID" value="XM_001418781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZL9"/>
    <dbReference type="STRING" id="436017.A4RZL9"/>
    <dbReference type="GeneID" id="5002615"/>
    <dbReference type="Gramene" id="ABO97111">
        <property type="protein sequence ID" value="ABO97111"/>
        <property type="gene ID" value="OSTLU_15984"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15984"/>
    <dbReference type="eggNOG" id="KOG2095">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043346_0_0_1"/>
    <dbReference type="OMA" id="DNAMEEN"/>
    <dbReference type="OrthoDB" id="5723at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009314">
        <property type="term" value="P:response to radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052230">
        <property type="entry name" value="DNA_polymerase_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873:SF1">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="8">
        <location>
            <begin position="30"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="47268" checksum="81789DFB303A36EF" modified="2007-05-15" version="1">MRTRGSQEKGATDDGFGGERPTSKRRGRCVAHVDADAFFAAVEKQRNPRLRDVPVAVRQHGDIICVDHRARELGATKHMNPDKCRALLTPHGGEVVHVHSTDDHMLSYEPYTRASYELHAKLYAACERLRVDGGTLIYQRASVDEAYVQLENGAKPSQRGKAFAESIRRAIAEECGYSVSVGVARNKMLAKIASKLAKPNGVVVIEDEADLERCFRQLPSSHLPKCNEPLIRRNLALHNLRTAWDVRELNAKRLEALVGLTRERALALCKAAHGVDDSEVVHKVHEKNTLSSSMTLTMVPKPLPKNVGSDVGVTGGPAGWYNPLTCGERERIGLTLGARARDLYSTIKVHQAYTERWPSTLTVKMAIEGTSVQYSKSAAFPVKFEDATSETAEDVLTKKATELALLTVGKRTTDKIREVAVVNSNSKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S011</accession>
    <name>A4S011_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_87742</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418663.1">
        <property type="nucleotide sequence ID" value="XM_001418626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S011"/>
    <dbReference type="STRING" id="436017.A4S011"/>
    <dbReference type="GeneID" id="5002874"/>
    <dbReference type="Gramene" id="ABO96956">
        <property type="protein sequence ID" value="ABO96956"/>
        <property type="gene ID" value="OSTLU_87742"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87742"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022397_0_0_1"/>
    <dbReference type="OMA" id="WDKSEKE"/>
    <dbReference type="OrthoDB" id="442633at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF384">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="58263" checksum="C58AFBBDDF4251B6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-30" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S068</accession>
    <name>MTNA_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="1">M1Pi</shortName>
            <shortName evidence="1">MTR-1-P isomerase</shortName>
            <ecNumber evidence="1">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ORF">OSTLU_35743</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-(methylsulfanyl)-alpha-D-ribose 1-phosphate = 5-(methylsulfanyl)-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418690.1">
        <property type="nucleotide sequence ID" value="XM_001418653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S068"/>
    <dbReference type="SMR" id="A4S068"/>
    <dbReference type="STRING" id="436017.A4S068"/>
    <dbReference type="EnsemblPlants" id="ABO96983">
        <property type="protein sequence ID" value="ABO96983"/>
        <property type="gene ID" value="OSTLU_35743"/>
    </dbReference>
    <dbReference type="GeneID" id="5002974"/>
    <dbReference type="Gramene" id="ABO96983">
        <property type="protein sequence ID" value="ABO96983"/>
        <property type="gene ID" value="OSTLU_35743"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35743"/>
    <dbReference type="eggNOG" id="KOG1468">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_1_3_1"/>
    <dbReference type="OMA" id="CETRPLN"/>
    <dbReference type="OrthoDB" id="2461at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.420:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10470:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="entry name" value="translation initiation factor eif-2b, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004326">
        <property type="entry name" value="PRK05720.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475:SF1">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0486">Methionine biosynthesis</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000401994" description="Methylthioribose-1-phosphate isomerase">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03119"/>
        </source>
    </evidence>
    <sequence length="365" mass="38658" checksum="3738885C6C4E59F5" modified="2007-05-15" version="1">MSSLEAIRYARGNLELLDQLALPLETKYIDVRDCNACWRCIKDMNVRGAPAIAIAAALALAVELEAKRGTLTTCEAAEAFVRERFDHMYTSRPTAVNLGEAKNRIQALAKRLSESGDVSGMIEGVIEGCEAMHAEDVASCRAIGDKGAAALLRACGAKDGENIKVMTCCNTGSLATAGYGTALGVIRALWESGRLERAYCLETRPYNQGSRLTAYELVYEKIPGTLICDNMAAALMARGDVDAIVVGADRVAANGDFANKIGTYSLAVNAKHHGVPMFTAAPVTTLDPETATGADIHIEERPGEEVTHSLGKRVAAEGIDVWNPSFDVTPAALLTGVITEHGVIEKNASGLFPVADFVAQAKGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S069</accession>
    <name>A4S069_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-methyl-5-thioribose kinase</fullName>
            <ecNumber evidence="3">2.7.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_3520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylthioribose kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.100" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418691.1">
        <property type="nucleotide sequence ID" value="XM_001418654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S069"/>
    <dbReference type="STRING" id="436017.A4S069"/>
    <dbReference type="GeneID" id="5002765"/>
    <dbReference type="Gramene" id="ABO96984">
        <property type="protein sequence ID" value="ABO96984"/>
        <property type="gene ID" value="OSTLU_3520"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3520"/>
    <dbReference type="eggNOG" id="ENOG502QVM3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033681_0_0_1"/>
    <dbReference type="OMA" id="EMCEITE"/>
    <dbReference type="OrthoDB" id="2461at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046522">
        <property type="term" value="F:S-methyl-5-thioribose kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009212">
        <property type="entry name" value="Methylthioribose_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01767">
        <property type="entry name" value="MTRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34273">
        <property type="entry name" value="METHYLTHIORIBOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34273:SF2">
        <property type="entry name" value="METHYLTHIORIBOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031134">
        <property type="entry name" value="MTRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="406" mass="44849" checksum="5CF35535F16D15AF" modified="2007-05-15" version="1" fragment="single">GFIALNCETVLDYAASKENVAKVLGGASTRASWSAKEIGDGNINFVYIVTGASANKSVIVKQGLPFVRCVGESWPLTQERVRYEAEALIQAHKFCPEHVPEVYVYDATMATIVMRYLEPPHIILRGGIIEGKVYPKLAEHVGEYLATTLYKSSALAVGGAELRRARQAFGQNEDMCELTEQVIFTEPYGKADNNHWTTPQLDDIVGEIQSDAALKRAINALKEKFMTEAQALLHGDLHTGSLMCTETTTFAIDNEFAFYGPMGFDIGAFLANLLLAYFSQNGWAKCNGEDRGAQRDWLLSAFASTWGIFEKRFLEQWNEQGVRDDCGGLSPAILYGKDVKSGASALEEHQRTFMRKIWADTLGFAGAKMIRRIIGIAHVADLDKIPDANVRAQCERAALKCGRELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0P6</accession>
    <name>A4S0P6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">MC family transporter: uncoupling protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_16269</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419016.1">
        <property type="nucleotide sequence ID" value="XM_001418979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0P6"/>
    <dbReference type="GeneID" id="5003011"/>
    <dbReference type="Gramene" id="ABO97309">
        <property type="protein sequence ID" value="ABO97309"/>
        <property type="gene ID" value="OSTLU_16269"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16269"/>
    <dbReference type="eggNOG" id="KOG0753">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_14_2_1"/>
    <dbReference type="OMA" id="HARRYCS"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000019">
        <property type="entry name" value="Mitochondrial uncoupling protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00784">
        <property type="entry name" value="MTUNCOUPLING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="20"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="124"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="223"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="315" mass="33210" checksum="648A98A74F4CBD2F" modified="2007-05-15" version="1">MAREGDATATRTKTKTPLVNPFLGGLAASAFSASFAEFCTIPLDTVKVRLQLRGASATATATTRGRGAGMLGTMRAVAAEEGIGALWKGITPGIHRQVLFGGLRIGLYEPVKTFYVGEEHVGDVPLHLKIAAGLTTGGIGIMVASPTDLVKVRMQAEGKLAPGTPKKYPSAVGAYGVIVRQEGLAALWTGLTPNIMRNSIVNAAELASYDQFKQSFLGVGMKDDVVTHIASALGAGFVACCVGSPVDVVKSRVMGDSTGKYKGFVDCVTKTLANEGPMAFYGGFLPNFARLGGWNVCMFLTLEQVRKLMRDNNIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0W4</accession>
    <name>A4S0W4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_24885</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419258.1">
        <property type="nucleotide sequence ID" value="XM_001419221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0W4"/>
    <dbReference type="GeneID" id="5003078"/>
    <dbReference type="Gramene" id="ABO97551">
        <property type="protein sequence ID" value="ABO97551"/>
        <property type="gene ID" value="OSTLU_24885"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24885"/>
    <dbReference type="eggNOG" id="KOG0584">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_142_5_1"/>
    <dbReference type="OMA" id="MENEIHL"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13983">
        <property type="entry name" value="STKc_WNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000075">
        <property type="entry name" value="Probable serine/threonine-protein kinase WNK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001565">
        <property type="entry name" value="WNK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024678">
        <property type="entry name" value="Kinase_OSR1/WNK_CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050588">
        <property type="entry name" value="WNK_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13902">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12202">
        <property type="entry name" value="OSR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="90"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="502"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="613"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="628"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="648" mass="72611" checksum="541B177E1A3F62EB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S134</accession>
    <name>A4S134_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419082.1">
        <property type="nucleotide sequence ID" value="XM_001419045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S134"/>
    <dbReference type="GeneID" id="5003348"/>
    <dbReference type="Gramene" id="ABO97375">
        <property type="protein sequence ID" value="ABO97375"/>
        <property type="gene ID" value="OSTLU_32959"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32959"/>
    <dbReference type="HOGENOM" id="CLU_1790152_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672061" evidence="2">
        <location>
            <begin position="29"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="145" mass="14993" checksum="99E2003B1F3A3E0E" modified="2007-05-15" version="1">MLGKTLKFQALVIALVAVSCVIEDGAQAIAKKITRCVVRDFTLATVSHIAAGAASSTKKALAKVMLLMHAFSLFDVYVRGSSCCPTKLMAAQACAGALAYGLYGGALPIPKIGGGKKKSAKKSSSSAKKATPKRASSRSSSRSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4S165</accession>
    <name>A4S165_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2 7">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_50249</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="2 7"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419309.1">
        <property type="nucleotide sequence ID" value="XM_001419272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S165"/>
    <dbReference type="STRING" id="436017.A4S165"/>
    <dbReference type="GeneID" id="5003434"/>
    <dbReference type="Gramene" id="ABO97602">
        <property type="protein sequence ID" value="ABO97602"/>
        <property type="gene ID" value="OSTLU_50249"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50249"/>
    <dbReference type="eggNOG" id="KOG0169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002738_3_2_1"/>
    <dbReference type="OMA" id="LAVYCHA"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="10">
        <location>
            <begin position="207"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="310"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="495" mass="54795" checksum="BFDF0C53152411F7" modified="2007-05-15" version="1">MTDELSHYFVNSSHNTYLDGGQLFSRSTSSAIAWALERGCRVVELDCYDGGSKGPIITHGGTAVRPMLFKDAIAVINDRAHVASEYPVIVTLENHASRETRAVMAKIMRHTFGDKLWTPPSKGEGEGEEESYVLDRWPSPAELKGKVIIRDKSTKATLSTGKNKLSVANSVVNLSKSAPAGVPEDSDGTSEDDGGEDDEDIKALVSLRNLKFHGFKEAKDLGTKFSCSWSENKAKKLVEKSSQKDLLEFTKAHLLRTYPGGQRIMSNNYDPSDAWSIGASLVALNFQAQDRYMWVNQAKFAVNGGCGYVKKPDYLINPSVQRPTKPRILRIHVFCGLGWENFKDADFMSAPDTFMKISLFGCVADRLSATSRGNSMRTSVYSKARVGPCAQPIWNEHFDLEIREPELTVLQIQAMDKDGARDEFLAHYDVAVSALREGVRIVPLLARDDEYVHDSKSCAGVLCKFEWLDEKSSSNDALPARTNESKETTNISEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1C5</accession>
    <name>A4S1C5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRPL1</name>
        <name evidence="8" type="ORF">OSTLU_12802</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419341.1">
        <property type="nucleotide sequence ID" value="XM_001419304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1C5"/>
    <dbReference type="STRING" id="436017.A4S1C5"/>
    <dbReference type="GeneID" id="5003291"/>
    <dbReference type="Gramene" id="ABO97634">
        <property type="protein sequence ID" value="ABO97634"/>
        <property type="gene ID" value="OSTLU_12802"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12802"/>
    <dbReference type="eggNOG" id="KOG1569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062853_0_0_1"/>
    <dbReference type="OMA" id="MYIASSM"/>
    <dbReference type="OrthoDB" id="1747252at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000001">
        <property type="entry name" value="50S ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_uL1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_uL1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_uL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_uL1_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="209" mass="21975" checksum="CA2118380E4CA4CC" modified="2007-05-15" version="1">MKSSATAKFDESAELHIRLNIDPKYNDQQLRATVALPKGTGKNVRVAVLCAGDNIAAAKAAGADFAGDDDLVDEIAGGMMDFDLLVATPDMMPKVAKLGRQLGPKGLMPNPKAGTVTTDVTTTVNEFKGGKVEFRADKQGIVHVPFGKLSFSAADLKENLLSVVGAIDANRPVGAKGVYWRSMYIASSMGPSVQVDVPQARDEVAALSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1E8</accession>
    <name>A4S1E8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_50173</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PRL1/PRL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419137.1">
        <property type="nucleotide sequence ID" value="XM_001419100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1E8"/>
    <dbReference type="STRING" id="436017.A4S1E8"/>
    <dbReference type="GeneID" id="5003240"/>
    <dbReference type="Gramene" id="ABO97430">
        <property type="protein sequence ID" value="ABO97430"/>
        <property type="gene ID" value="OSTLU_50173"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50173"/>
    <dbReference type="eggNOG" id="KOG0285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_72_0_1"/>
    <dbReference type="OMA" id="FAMCFDQ"/>
    <dbReference type="OrthoDB" id="10256122at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000012">
        <property type="entry name" value="Putative pleiotropic regulator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045241">
        <property type="entry name" value="Prp46/PLRG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923:SF0">
        <property type="entry name" value="PLEIOTROPIC REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923">
        <property type="entry name" value="WD40 REPEAT PROTEINPRL1/PRL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="75"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="117"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="159"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="201"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="284"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="389" mass="43161" checksum="34068B810C70361B" modified="2007-05-15" version="1">MIDALDDEDERDGGSQAGPSKALAAFRGEDAKANLPVSIFGRHANAATGANIAKRLASEWPEPEWRAPWKLYRVISGHQGWVRSCAVDPGNEWFVTGSADRTIKVWDLASGSLKLTLTGHIEQVTGIVVSQRHPYMFSCGLDKKVKCWDLEYNKVIRNYHGHLSGVYSIAMHPTLDLLMTGGRDSVCRVWDMRTKRQVYCLTGHENTVGSILAQDENPQLVTGSYDSTVRLWDLATGKTIHTLTHHKKGVRAMAMHKKEFAFVSASADNIKKFSCHGDFMHNMLSKQNSIVNTLSMNDDDVVFSGGDNGSMCFWDYKSGHCFQQEKALVQPGSLEAECGIYASTFDVTGSRLITCEADKTIKMWKEDTEATPESAPILPFAPPKNIRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1M3</accession>
    <name>A4S1M3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419389.1">
        <property type="nucleotide sequence ID" value="XM_001419352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1M3"/>
    <dbReference type="GeneID" id="5003175"/>
    <dbReference type="Gramene" id="ABO97682">
        <property type="protein sequence ID" value="ABO97682"/>
        <property type="gene ID" value="OSTLU_33149"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33149"/>
    <dbReference type="HOGENOM" id="CLU_2227699_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="106" mass="11693" checksum="B7AB1F889396CF41" modified="2007-05-15" version="1">MEIERDVAVETARALKEELAAAKERAAALAATVARLRERLQSTRGDEERMGMGRIATGASWSKSDDFDVPTPRGTLTLSPVASEAPRREYSVDLLELIESVERESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1R9</accession>
    <name>A4S1R9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_42421</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419195.1">
        <property type="nucleotide sequence ID" value="XM_001419158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1R9"/>
    <dbReference type="STRING" id="436017.A4S1R9"/>
    <dbReference type="GeneID" id="5003109"/>
    <dbReference type="Gramene" id="ABO97488">
        <property type="protein sequence ID" value="ABO97488"/>
        <property type="gene ID" value="OSTLU_42421"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42421"/>
    <dbReference type="eggNOG" id="KOG0924">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_6_5_1"/>
    <dbReference type="OMA" id="VDVMFHR"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000615">
        <property type="entry name" value="pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000018">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="282"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="459"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="177"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="902"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="908"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="946"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO97488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="989" mass="110894" checksum="7FE0F63114687C4F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1V2</accession>
    <name>A4S1V2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_33231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419431.1">
        <property type="nucleotide sequence ID" value="XM_001419394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1V2"/>
    <dbReference type="STRING" id="436017.A4S1V2"/>
    <dbReference type="GeneID" id="5003128"/>
    <dbReference type="Gramene" id="ABO97724">
        <property type="protein sequence ID" value="ABO97724"/>
        <property type="gene ID" value="OSTLU_33231"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33231"/>
    <dbReference type="eggNOG" id="KOG2210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753137_0_0_1"/>
    <dbReference type="OMA" id="LRWKFEF"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="41898" checksum="1D4A112AA2E3369B" modified="2007-05-15" version="1">MEAESRGGSFAAKARAYAKAVTAMASVAARGGRVDLTSFLGTPIRWCARISLLRTVTDSASSVSSDAPSRTVRFFEMLRRVDAERDDAVTRFAGVALAMIAEIEPPASLKKPLNPVLGETAIHSVVFPNERFESVWEQVSHHPPISAHCTRGSNVRVEGELRPKPHLVGAHIEVELEGEARITLIDRDETYVSDLPSFEWRFVPRWHSRMTRKRKWSIRCEKTGLRGEFTYAAKRGVRGVVYSTWSGAAVCEIDGRYDGSVVAKKISSGEAVARYDLEDAKRFRGQIVRHTHLDDERDTEVVWKETFKAMEENRWDDAKNAKKRVEESEREKRREREARGETFEPRFFTLDERLGRWVRDTRAQVVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S265</accession>
    <name>A4S265_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylglucosaminylphosphatidylinositol deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_34729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGL family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419479.1">
        <property type="nucleotide sequence ID" value="XM_001419442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S265"/>
    <dbReference type="STRING" id="436017.A4S265"/>
    <dbReference type="GeneID" id="5003902"/>
    <dbReference type="Gramene" id="ABO97772">
        <property type="protein sequence ID" value="ABO97772"/>
        <property type="gene ID" value="OSTLU_34729"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34729"/>
    <dbReference type="eggNOG" id="KOG3332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034979_1_0_1"/>
    <dbReference type="OMA" id="YVLESVN"/>
    <dbReference type="OrthoDB" id="440160at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF11">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="275" mass="30216" checksum="FF9E3DD0E7A1D51C" modified="2007-05-15" version="1">MKRDVVVTSVAFAGAAVACSLVALRITRKIRTRTGLDPFAVPNGSSREKGADGRKAALVLTSHPDDESYFFAPTIQALKAANVETHLVCLSDGGAGGDGETRKKELLRVKELFELEGMCIVEAEDLMDGMTNAWPAKTVMTVLDEYTGGAPTTFDYVVTFDAGGVSGHLNHVCTYEGTKQWIEERKVSISSDRGGCPQVWVLETTNAARKLSGALDFATSYLESLIDSRRVFVPSASPMQVLKAVRLHASQFVWYRKIFVVFSRYTYMNTLRRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S272</accession>
    <name>A4S272_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein TIC 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_33348</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in protein precursor import into chloroplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Tic20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419482.1">
        <property type="nucleotide sequence ID" value="XM_001419445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S272"/>
    <dbReference type="STRING" id="436017.A4S272"/>
    <dbReference type="GeneID" id="5003636"/>
    <dbReference type="Gramene" id="ABO97775">
        <property type="protein sequence ID" value="ABO97775"/>
        <property type="gene ID" value="OSTLU_33348"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33348"/>
    <dbReference type="eggNOG" id="ENOG502QT65">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094758_1_0_1"/>
    <dbReference type="OMA" id="WMELWIF"/>
    <dbReference type="OrthoDB" id="602284at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005691">
        <property type="entry name" value="Tic20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510:SF9">
        <property type="entry name" value="HIT-TYPE ZINC FINGER FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16166">
        <property type="entry name" value="TIC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="22337" checksum="42F97E6BAB880985" modified="2007-05-15" version="1">MPFRPSPNGNKGKGFLELWFGRDEANEGKIRPAPYLRILAVIPFVIPLMGTIAFTHSAYEFLPLFKHAMFIFAPAMQLFYGNSFIPFMTFFALFLLVVRNEKIPYFVRYCTMQAILLDICCMLGGLIMQYMPIFIMVSWVGEWMELWIFVNSFFALGYSIFNALQGLIPEAPLISEAVYAQVQEARDTGYMEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S344</accession>
    <name>A4S344_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_33669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419853.1">
        <property type="nucleotide sequence ID" value="XM_001419816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S344"/>
    <dbReference type="SMR" id="A4S344"/>
    <dbReference type="STRING" id="436017.A4S344"/>
    <dbReference type="GeneID" id="5003858"/>
    <dbReference type="Gramene" id="ABO98146">
        <property type="protein sequence ID" value="ABO98146"/>
        <property type="gene ID" value="OSTLU_33669"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33669"/>
    <dbReference type="eggNOG" id="KOG2731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_797849_0_0_1"/>
    <dbReference type="OMA" id="FKWHKDS"/>
    <dbReference type="OrthoDB" id="6614653at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035515">
        <property type="term" value="F:oxidative RNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035513">
        <property type="term" value="P:oxidative RNA demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004574">
        <property type="entry name" value="Alkb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557:SF2">
        <property type="entry name" value="NUCLEIC ACID DIOXYGENASE ALKBH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="213"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604574-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="37821" checksum="E3046B187E90436C" modified="2007-05-15" version="1">MDDARDATGGEGARGRCQKLAKALRGQLAKKAYDALRAHARAFQRREVTTSEFAKVLVECARTGGVTRATAREVIATTPSALDRRRLRECVGRDLDDDAAVKSTREREKKPHGFKTERLGPGLVCLRKFLSVEAQMWLASESFALGESGSDDAARGQGFFAKMGDGTFKLNQGSRGRMILEPDAFPDGILTQMCEDAVAAACAADAEMPTNMNPTTCLVNFYKDGAEFKWHKDSEDPKLVKSRTGPPIVSFSVGLSGDFGYKYSFDDPEHKVVRLNSGDVLLFGGPSRMIVHSVLNVYPGSMPGHLRGKMLNGRLNVTVRDIGCGVIDASQFPAYRVSYDGVQADGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S391</accession>
    <name>A4S391_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_25974</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419876.1">
        <property type="nucleotide sequence ID" value="XM_001419839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S391"/>
    <dbReference type="STRING" id="436017.A4S391"/>
    <dbReference type="GeneID" id="5004204"/>
    <dbReference type="Gramene" id="ABO98169">
        <property type="protein sequence ID" value="ABO98169"/>
        <property type="gene ID" value="OSTLU_25974"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25974"/>
    <dbReference type="HOGENOM" id="CLU_1645992_0_0_1"/>
    <dbReference type="OMA" id="DSTCYIA"/>
    <dbReference type="OrthoDB" id="498939at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="84"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="27"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="179" mass="20315" checksum="11D2B651749E96FE" modified="2007-05-15" version="1">MIARDRTVTATTSEVERRQDALRELQTRAEEAARLVAKGKKKTQQKKNNDDNDDGARRRDRASSSNYDEERAVRSPQEVLLLQREMLDEQDEALDDLSVAAERTKDISLAVNDELDLHAKLLDGLEDDVEDTRGRLHLASRAVKRMMRRGSNCRQYSIVALVLVVCVLMLCLIIKLQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3A8</accession>
    <name>A4S3A8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_94783</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419887.1">
        <property type="nucleotide sequence ID" value="XM_001419850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3A8"/>
    <dbReference type="STRING" id="436017.A4S3A8"/>
    <dbReference type="GeneID" id="5004236"/>
    <dbReference type="Gramene" id="ABO98180">
        <property type="protein sequence ID" value="ABO98180"/>
        <property type="gene ID" value="OSTLU_94783"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94783"/>
    <dbReference type="eggNOG" id="ENOG502QWD8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054919_3_2_1"/>
    <dbReference type="OMA" id="FWMNREL"/>
    <dbReference type="OrthoDB" id="21573at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="entry name" value="Translation initiation factor 3 (IF-3), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="entry name" value="Translation initiation factor 3 (IF-3), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938:SF0">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="Translation initiation factor IF3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="Translation initiation factor IF3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 3 N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Translation initiation factor 3 C-terminal" evidence="4">
        <location>
            <begin position="61"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16854" checksum="AF645AE9FCD28F7A" modified="2007-05-15" version="1">MALEEAMAAAKAAGMDLVEVNGNASPPVCRILDYERVRYDIRKRAKEQKKAVSAAQKRDVIKELRLTAKIDVHDLNVKINGAKKFLDAGNRVTFRIMFKNSDGIAQDKRATRGAEIMDNIISMLEDVEVVLKPKMVGANHMTCSLKRPTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3H9</accession>
    <name>A4S3H9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="7">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_38305</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="7"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419921.1">
        <property type="nucleotide sequence ID" value="XM_001419884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3H9"/>
    <dbReference type="STRING" id="436017.A4S3H9"/>
    <dbReference type="GeneID" id="5004253"/>
    <dbReference type="Gramene" id="ABO98214">
        <property type="protein sequence ID" value="ABO98214"/>
        <property type="gene ID" value="OSTLU_38305"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38305"/>
    <dbReference type="eggNOG" id="KOG0534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_9_2_1"/>
    <dbReference type="OMA" id="LDMKGPF"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009703">
        <property type="term" value="F:nitrate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006809">
        <property type="term" value="P:nitric oxide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF185">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="27"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="285" mass="30837" checksum="FECFE91477251FA5" modified="2007-05-15" version="1">MKQEETPTSARPVVEYPEGTLATLKNGETVELKLVEKEQVTSNTVRLRFELPSPEHILGLPVGQHVTVTIDGVSRPYTPITRDADKGFMDLLVKIYDQGALTQKLNAVAVGSTVAFEGPNGLVTYSARGEFSTRNPATGSVAKKSCKNIAMIAGGTGITPMLQVIRQIFNDVGDTTRVNLLFANVSSADILLKKELDELASAHKNLTVHYAIDKDEPNWNGEVGYVSEEMIKKCDLLKRGGLMDKLFSSADDTAVLVCGPPAMVEKAVVPALDALNVSTDSRIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3K2</accession>
    <name>A4S3K2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420109.1">
        <property type="nucleotide sequence ID" value="XM_001420072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3K2"/>
    <dbReference type="STRING" id="436017.A4S3K2"/>
    <dbReference type="GeneID" id="5004266"/>
    <dbReference type="Gramene" id="ABO98402">
        <property type="protein sequence ID" value="ABO98402"/>
        <property type="gene ID" value="OSTLU_26083"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26083"/>
    <dbReference type="eggNOG" id="ENOG502S5F8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148782_2_1_1"/>
    <dbReference type="OrthoDB" id="2100988at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="84" mass="8911" checksum="0309C620E39F36D2" modified="2007-05-15" version="1">MGAPASGGGPTSVTGHVWTTYGGWFADPKAWKRNTVGGFVALGALAMMTFNYSRAREKRPIYPAHAIPSQRWSGAFDANGPKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Y3</accession>
    <name>A4S3Y3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_94891</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420173.1">
        <property type="nucleotide sequence ID" value="XM_001420136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Y3"/>
    <dbReference type="GeneID" id="5004040"/>
    <dbReference type="Gramene" id="ABO98466">
        <property type="protein sequence ID" value="ABO98466"/>
        <property type="gene ID" value="OSTLU_94891"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94891"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016265_1_1_1"/>
    <dbReference type="OMA" id="HGRGKWC"/>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="4">
        <location>
            <begin position="47"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="434" mass="48366" checksum="5835BDD91125D925" modified="2007-05-15" version="1">MGHESADDATATATAAGDDGKAKKPWGFLSPFGASAAVLEQAAEANEKQSGRRRRTEEVKLKVDGQWYDATGWALAHPGGAGFVRLLNGQDATDVFYALHSYGPNGSDEALKRLRALPKCDAPYDTEEYETQRLTTANAEFGELRGKLEAEGWFKRNALSELSVLAQVLGCYVVGQAIAATHPILAAISIGIGMQQAGWLAHDYVHGRGKWCSMMRCFGALTNGFSAEWWSHKHNMHHSFTNVDGKDGDIKLEPLYYLSPPETSGRPDSWLRKYQHIYGYPLYAMTVASAWARKDKTELALLVGHYAWLFGTLPLGVAIGSMLIGGFLVGSLVTATHQSEEIMYEDGSFVDIQFRSTREADVKNPLERWLWGGMDTQLIHHLFPTMPRYKLHKLRPIMQEWAQKHGYDFRISDSRDILKKNYKHLEGIAALETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4A8</accession>
    <name>A4S4A8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420399.1">
        <property type="nucleotide sequence ID" value="XM_001420362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4A8"/>
    <dbReference type="STRING" id="436017.A4S4A8"/>
    <dbReference type="GeneID" id="5004277"/>
    <dbReference type="Gramene" id="ABO98692">
        <property type="protein sequence ID" value="ABO98692"/>
        <property type="gene ID" value="OSTLU_26345"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26345"/>
    <dbReference type="eggNOG" id="ENOG502QVD0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054121_0_0_1"/>
    <dbReference type="OMA" id="LTHFSMR"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46504">
        <property type="entry name" value="TRNASE Z TRZ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46504:SF2">
        <property type="entry name" value="TRNASE Z TRZ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="313" mass="34309" checksum="9E021AE71D141F0E" modified="2007-05-15" version="1">MATARDRPAGREGDGEGDGDGDDAAQKRTKNRDRHAVHELAGYKIEGVSVGGRETSVVLPALGVAFDSGRCPQRCVYADVMCLSHTHMDHVGGCGMYIATRGLLSLTPPTVLLPSARREAFGTFIESLRALDDSELNHRAIGIDPGERYAMNKLFEIAAFRTRHPVPSQGYVVYGTKQKLKPAYAGLSGPEIKRLRDDGEQVTDKVEVPEVAFTGDTTGDWIDDPANADALRAKLLIMECTFIDDAVSKHDAERFGHTHIDDIVARADKFQNEAILLIHFSARYKAEEVRAALKAKLPRALYEKCTPMLVGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4D2</accession>
    <name>A4S4D2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_19724</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420414.1">
        <property type="nucleotide sequence ID" value="XM_001420377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4D2"/>
    <dbReference type="STRING" id="436017.A4S4D2"/>
    <dbReference type="GeneID" id="5004318"/>
    <dbReference type="Gramene" id="ABO98707">
        <property type="protein sequence ID" value="ABO98707"/>
        <property type="gene ID" value="OSTLU_19724"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19724"/>
    <dbReference type="eggNOG" id="KOG1308">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026202_0_0_1"/>
    <dbReference type="OMA" id="NATIREC"/>
    <dbReference type="OrthoDB" id="533763at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14438">
        <property type="entry name" value="Hip_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034649">
        <property type="entry name" value="Hip_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45883">
        <property type="entry name" value="HSC70-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45883:SF2">
        <property type="entry name" value="HSC70-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18253">
        <property type="entry name" value="HipN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="STI1" evidence="4">
        <location>
            <begin position="280"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="223"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="371" mass="39040" checksum="3F4B3D538CA2D3B7" modified="2007-05-15" version="1">MTRERAPTTATLEALRHLVRAAKEDSAILDAPALEFFRRWLEEDLGATIPAPRTTTTTGTGTDAIEIEDDEAMAAESDDLSAIAMGAETAPETLGEAEEAKASEAKRLASEAFAREAWEEAIERYTEALMIAPSALTYAKRAECFIKLRKPLSAIRDGTAALKLNPDSAKALKVRGAAHRYLGHWNEANADLSAGLSQDFDETYGEMHKKVLSVVHELHVREGKARAAKEAKEREELEKRRAAAEAARKEAAAKDAGGPGFGQPGAGFPGGAGDLPPGVSPEMAQKLMSDPDLIAAMQNPKVMQALQTMMKNPMAAMQYMSDPEVGPVLQKLMASMGGAMPGGAPGGFPGGFPGGFPGAGAAPGGAANDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4P7</accession>
    <name>A4S4P7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">POT family transporter: dipeptide/tripeptide:proton</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_50811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420473.1">
        <property type="nucleotide sequence ID" value="XM_001420436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4P7"/>
    <dbReference type="GeneID" id="5004597"/>
    <dbReference type="Gramene" id="ABO98766">
        <property type="protein sequence ID" value="ABO98766"/>
        <property type="gene ID" value="OSTLU_50811"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50811"/>
    <dbReference type="eggNOG" id="KOG1237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_0_2_1"/>
    <dbReference type="OMA" id="LWDWQAR"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050171">
        <property type="entry name" value="MFS_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23517:SF15">
        <property type="entry name" value="PROTON-DEPENDENT OLIGOPEPTIDE FAMILY TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23517">
        <property type="entry name" value="RESISTANCE PROTEIN MDTM, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="449" mass="47631" checksum="AF4C0DEC1FA24678" modified="2007-05-15" version="1">MRGAHPLGLVVLGATEMWERFGYYAARALLALYVTKVLRDPTFDVERVLGLRTVGKTDAVGMMERTRAAEATSAKTYGAFACLAYLTPVFGGIVADAVLGAHRSAVVGAVVMALGYGAMASEWAFLIGLALVCVGNGAFKPSISTQLSALYAKDDPKRDAGFSIFYCCINVGAFFSPLIAGTVRVYFGYGAAFASAAVGMWCALAIYALNRRHVVDAMIPASANDNDEDLNDMARLIRENSNAMFAVAIVCVAGIGFSMVYEQSGSTLMLFSDEHVDLHGMPTEFVAALNPLLVLSLTPAVTALWDWQARRGAEPHQMSKIAIGCALLSSSFAVLMFGALPIDSHASPTRVSVFWIVLNQIFLTAGELFTFPVALSYISKIAPDGLLSAIIGLWFGSYFFGNYFSGVLGSTYPSFDSPSGFFAALALIAGAVALVLGLARAPLAARCPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4T6</accession>
    <name>A4S4T6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420323.1">
        <property type="nucleotide sequence ID" value="XM_001420286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4T6"/>
    <dbReference type="STRING" id="436017.A4S4T6"/>
    <dbReference type="GeneID" id="5004380"/>
    <dbReference type="Gramene" id="ABO98616">
        <property type="protein sequence ID" value="ABO98616"/>
        <property type="gene ID" value="OSTLU_26523"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26523"/>
    <dbReference type="eggNOG" id="KOG1343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2162637_0_0_1"/>
    <dbReference type="OMA" id="CCKEVMC"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47665">
        <property type="entry name" value="HISTONE DEACETYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47665:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="111" mass="11798" checksum="CEE45A4382B2150C" modified="2007-05-15" version="1">MTRTCAHGARVDARRAREACEACEACGTRRELWRCLTCGDASCGRYANGHSRAHARASEGGCVVMLSWDDLSVWCHECESYVDPESSAALRACVAAAALAKFGDRDGGGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-02-05" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S562</accession>
    <name>A4S562_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_17464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420387.1">
        <property type="nucleotide sequence ID" value="XM_001420350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S562"/>
    <dbReference type="STRING" id="436017.A4S562"/>
    <dbReference type="GeneID" id="5004502"/>
    <dbReference type="KEGG" id="olu:OSTLU_17464"/>
    <dbReference type="eggNOG" id="KOG1253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010862_5_1_1"/>
    <dbReference type="OMA" id="VFYNPVM"/>
    <dbReference type="OrthoDB" id="6349953at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160104">
        <property type="term" value="F:tRNA (guanine(26)-N2)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002940">
        <property type="term" value="P:tRNA N2-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF9">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="430" mass="46300" checksum="4CC1F60F4FFBB830" modified="2007-05-15" version="1" fragment="single">MASRRRDAPRGDARASARRERGRDIRVTTTTFYRAESAQGRDLGVLAALTTRRRLEVLDATCASGARAARYAEAGVLKSMHANDVNADVEDVVRENLADLLSPASEVDVKLTFDDAQRVFARAWLEKTFYDVVDVDGFGAANFGDALKCVKYGGLFYATSTDARALCGQNPETLSRAFGNAVVAPSRPGVNEIALRVFIGDVVRRGAAIGISATPLFSLFHPHGPVFRVMFRVEKARGGAYDAFASNRDAAMGFVGFCDRCGDTSVVRAPLIDVYGHTKTIAPGDDDATTQCARCRGEGSAEDTRSAALAISGPLWLRSLHDRDTVLAMIEAADAQGWFAADDESDTGPVKGQLSLRDLLDAFVGEADAGLERTPHHLRTDELGRRGRAKRVPPRDVLITALRAEGFAATRSHIDPRGLKTNATMADVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S592</accession>
    <name>A4S592_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein mS38 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420566.1">
        <property type="nucleotide sequence ID" value="XM_001420529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S592"/>
    <dbReference type="GeneID" id="5004752"/>
    <dbReference type="Gramene" id="ABO98859">
        <property type="protein sequence ID" value="ABO98859"/>
        <property type="gene ID" value="OSTLU_17486"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17486"/>
    <dbReference type="HOGENOM" id="CLU_1613559_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="COX24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="2">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="17798" checksum="226F49C453E52E66" modified="2007-05-15" version="1">MGRWTRACGALARRALAIEIRAPARAPVMAMRALERRFATMTTTTTTTTTASAASAAAARGRGDATTTTTAAAAAATSADATTATVFGESARMVDARSNESDHGKHATTGMTVGALLGRLRALERDAERDIGGFFDMASVKRKRKKAMNKHKHRKRRRRDRHQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5B9</accession>
    <name>A4S5B9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420580.1">
        <property type="nucleotide sequence ID" value="XM_001420543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5B9"/>
    <dbReference type="STRING" id="436017.A4S5B9"/>
    <dbReference type="GeneID" id="5004816"/>
    <dbReference type="Gramene" id="ABO98873">
        <property type="protein sequence ID" value="ABO98873"/>
        <property type="gene ID" value="OSTLU_17508"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17508"/>
    <dbReference type="HOGENOM" id="CLU_517413_0_0_1"/>
    <dbReference type="OMA" id="WCEVREI"/>
    <dbReference type="OrthoDB" id="73919at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="57124" checksum="56858A4A37D1BDBE" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5C2</accession>
    <name>A4S5C2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Right handed beta helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420545.1"/>
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    <dbReference type="AlphaFoldDB" id="A4S5C2"/>
    <dbReference type="GeneID" id="5004847"/>
    <dbReference type="Gramene" id="ABO98875">
        <property type="protein sequence ID" value="ABO98875"/>
        <property type="gene ID" value="OSTLU_17510"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17510"/>
    <dbReference type="eggNOG" id="ENOG502SBQN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="10631365at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
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        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319:SF35">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN PMPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="19"/>
        </location>
    </feature>
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            <begin position="20"/>
            <end position="414"/>
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            <begin position="171"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="414" mass="42040" checksum="57472660A4256BA0" modified="2007-05-15" version="1">MPRFVALALALSIVARSSAARVDASIDSRALRDAGALLDVPSDDAAWYAAASWDDNHYARALGTSTGRATTVTTTAELLAALRDPLVEFVEVNATTLTLDEDAWPRRGVAVRRRATLRGACDGRCVVDANGTSVASVVDGGSLTVERLAFEGARGDFGGAFYFGRAHGGGSFDDAAFEGCEAREGGAVFVASDARAGNVVFRNVTFESCGATATNGRGGGAFVAASGPAYVAFESCAFEGNVANGLGGGVYADGGHVVINECEFKTNAAASGGGAALRGGGVVSSSAFDGNDATRAGGGVHVASPSDVVVGHRASSVQRSAFTNNTAAVAGAGAFAYGRVKMLANTFSRNALPASAPSALDPNYYVCTDTSDAGCSMKPTLADDVYDPAAYDPFTPQTSFATVPETTTTTTTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5I5</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OMA" id="AMMSTII"/>
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        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="436"/>
        </location>
    </feature>
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        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="880" mass="98535" checksum="DE5779E9D21E6CD6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5J1</accession>
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        <recommendedName>
            <fullName evidence="6">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_39040</name>
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    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ABO98911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001420581.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S5J1"/>
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    <dbReference type="Gramene" id="ABO98911">
        <property type="protein sequence ID" value="ABO98911"/>
        <property type="gene ID" value="OSTLU_39040"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39040"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000539_1_0_1"/>
    <dbReference type="OMA" id="NWKERKE"/>
    <dbReference type="OrthoDB" id="205662at2759"/>
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        <property type="component" value="Chromosome 12"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:microtubule plus end polymerase"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="term" value="P:microtubule polymerization"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
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    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
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    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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            <end position="237"/>
        </location>
    </feature>
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        <location>
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            <end position="533"/>
        </location>
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        <location>
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            <end position="825"/>
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        <location>
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            <end position="1080"/>
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        </location>
    </feature>
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            <begin position="243"/>
            <end position="280"/>
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    </feature>
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        <location>
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            <end position="1894"/>
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    </feature>
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    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1899" mass="204938" checksum="C2E82F5C3C8FDA4F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5L5</accession>
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    <protein>
        <recommendedName>
            <fullName evidence="4 5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="6" type="ORF">OSTLU_93530</name>
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    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001420592.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S5L5"/>
    <dbReference type="GeneID" id="5004660"/>
    <dbReference type="Gramene" id="ABO98922">
        <property type="protein sequence ID" value="ABO98922"/>
        <property type="gene ID" value="OSTLU_93530"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93530"/>
    <dbReference type="eggNOG" id="KOG1225">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
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    </dbReference>
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        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EGF-like" evidence="4 5">
        <location>
            <begin position="632"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="842" mass="92883" checksum="9C0E241EE51CF6CB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5P2</accession>
    <name>A4S5P2_OSTLU</name>
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        <recommendedName>
            <fullName evidence="8">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_17595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO99098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5P2"/>
    <dbReference type="GeneID" id="5004904"/>
    <dbReference type="Gramene" id="ABO99098">
        <property type="protein sequence ID" value="ABO99098"/>
        <property type="gene ID" value="OSTLU_17595"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17595"/>
    <dbReference type="eggNOG" id="ENOG502S8K3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_547909_0_0_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="48"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="340"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="257"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="55355" checksum="3FDBA42FDA468538" modified="2007-05-15" version="1">MSSARAPVDARAGVETSKDDAHVSAVVRTDDDDDGFRDDAVTPAVTQARAAHHGRALRTASANGRTWTTGRKRRRSELGPLGTMGDLKTTPMQTPRVESDDVGLGGFNIAKRRSMSACKSVDVAGGSAGGSIGRERRRRTRRDSSSARASGGKRGTVDDDDGDGNETPGFEEDTPRSEWGGMSPGEYGGSQYVISPAREFSQCDSDEDRTARARAEKIRDDECKRDAAAARVQAEKDRQLKLYPIFRTGQKKVHLVRHGQSTWNAANSGPGSWDEPKMFDAALTELGRKQAKALGMALSKMPKNALWITSPLTRAIETCIIGRKAALEAKAAELNKAQRGGANVADDASPDENVDDLNTPLSTSSKKAFNPEREFEEWTSRLMIREELTEKLSCSGDVGRPRRCLEAEFPELELALSRIPEDRWWWEGCEHRPNDAQSEQFKSLEPQTNFKRRVARFRDWLLKRPEETFVVFGHSTFFKEFSKSERSMKNCEIHEMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5V1</accession>
    <name>A4S5V1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420675.1">
        <property type="nucleotide sequence ID" value="XM_001420638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5V1"/>
    <dbReference type="STRING" id="436017.A4S5V1"/>
    <dbReference type="GeneID" id="5004873"/>
    <dbReference type="Gramene" id="ABO98968">
        <property type="protein sequence ID" value="ABO98968"/>
        <property type="gene ID" value="OSTLU_26891"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26891"/>
    <dbReference type="eggNOG" id="ENOG502RZ9N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_345270_0_0_1"/>
    <dbReference type="OMA" id="REWMNDG"/>
    <dbReference type="OrthoDB" id="498721at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050:SF1">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="819" mass="93112" checksum="8A47946A28AB58C0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S610</accession>
    <name>A4S610_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoenolpyruvate carboxylase</fullName>
            <ecNumber evidence="4">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_51006</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>oxaloacetate + phosphate = phosphoenolpyruvate + hydrogencarbonate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="4"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420862.1">
        <property type="nucleotide sequence ID" value="XM_001420825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S610"/>
    <dbReference type="STRING" id="436017.A4S610"/>
    <dbReference type="GeneID" id="5004725"/>
    <dbReference type="Gramene" id="ABO99155">
        <property type="protein sequence ID" value="ABO99155"/>
        <property type="gene ID" value="OSTLU_51006"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51006"/>
    <dbReference type="eggNOG" id="ENOG502QPVS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006557_2_0_1"/>
    <dbReference type="OMA" id="GPTHRFI"/>
    <dbReference type="OrthoDB" id="1365747at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.90:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.90">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000584">
        <property type="entry name" value="PRK00009.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523:SF33">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="10">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1007" mass="113472" checksum="11D8902CC4CD234F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6I9</accession>
    <name>A4S6I9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420951.1">
        <property type="nucleotide sequence ID" value="XM_001420914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6I9"/>
    <dbReference type="GeneID" id="5004958"/>
    <dbReference type="Gramene" id="ABO99244">
        <property type="protein sequence ID" value="ABO99244"/>
        <property type="gene ID" value="OSTLU_27136"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27136"/>
    <dbReference type="HOGENOM" id="CLU_1899005_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="134" mass="14451" checksum="9586F6C2CF81A17C" modified="2007-05-15" version="1">MTRSRALVATRVTTRRGTATTRRARATRPKIESLGGFGPNIDAKEIQRRMAEKQRKIDENKRKARGAKEASTAFGARREFQRTISSARPSRAGRTMPGGGVAAGTTSSKTKTTSGKGGKGGKEEAPKKKLFGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6J0</accession>
    <name>A4S6J0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_93609</name>
        <name evidence="11" type="ORF">OSTLU_94170</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420952.1">
        <property type="nucleotide sequence ID" value="XM_001420915.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422942.1">
        <property type="nucleotide sequence ID" value="XM_001422905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6J0"/>
    <dbReference type="GeneID" id="5005158"/>
    <dbReference type="GeneID" id="5006911"/>
    <dbReference type="Gramene" id="ABO99245">
        <property type="protein sequence ID" value="ABO99245"/>
        <property type="gene ID" value="OSTLU_93609"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01301">
        <property type="protein sequence ID" value="ABP01301"/>
        <property type="gene ID" value="OSTLU_94170"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93609"/>
    <dbReference type="KEGG" id="olu:OSTLU_94170"/>
    <dbReference type="eggNOG" id="ENOG502QS41">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108326_0_0_1"/>
    <dbReference type="OMA" id="QTEQMGK"/>
    <dbReference type="OrthoDB" id="498056at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15861">
        <property type="entry name" value="SNARE_SNAP25N_23N_29N_SEC9N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044766">
        <property type="entry name" value="NPSN/SNAP25-like_N_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF79">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="130"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP01301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="223" mass="24469" checksum="8D2008343B345D84" modified="2007-05-15" version="1" fragment="single">VSSGHLKKLTNKMAESKKLIKEFERRALSEGAMDANALAAAKKEYVSRLNKFVQMKKEAQIAIAEKQEERKSEVGSQGGEASTSGGVTTSTTATSTAFTLPAFRPKPKGEIVEDEQLQLMEAGDLIDHGRNVMDQTDKSIMRSEAVVEETIQIGTQTAEALRGQTKQLEKIVDDLDEIHFSLKKSFGVLKDITRGLATDKCIMLLLFLVVVGVVVVIITRFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6N5</accession>
    <name>A4S6N5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421120.1">
        <property type="nucleotide sequence ID" value="XM_001421083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6N5"/>
    <dbReference type="GeneID" id="5004976"/>
    <dbReference type="Gramene" id="ABO99413">
        <property type="protein sequence ID" value="ABO99413"/>
        <property type="gene ID" value="OSTLU_27184"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27184"/>
    <dbReference type="HOGENOM" id="CLU_461819_0_0_1"/>
    <dbReference type="OrthoDB" id="496223at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673205" description="Sulfotransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="56728" checksum="21B0C325C05DBAF9" modified="2007-05-15" version="1">MAAVTLGTFLVLGRAGAFRGASARRAPLQAMDAGAGSAGGTASRPARRWMTHLLRDHPEMRCTQIPSKPVIVGGDGGGAGKPLMEFLRDSNAVTFGPTDKDGNSDAERLSGLDDMVVDVMAFSKRLLYEPDDLPMDLQADLAKHLCDMFARQEKWLHPGLTMNGIQHDQEVGRWGWKDPLAMYLVPIWRDVYGPSVTYVHLVRDPRTLPLGNLHDKERDLQKAYFGQERWEQLTAKFESEWAHLSQHQSMTSVKKDDVIDLLRTTAYWTSINFELGALIKGPLKNYATVLRAEDLVQPDMDHFRRDATGKKPEKYQAAQKVMQELTTLLKLPAKLSNTLGSHEHMKQNLRRFTIHREKFVYRTDSPIIEVQTRIAEKTLELFGYSADAALFVSRHPSSSEPHGHRLTPEGEYMHEEHRYTPDDFEPTIEPASEGDLPGITNHVLGAQLKYTDRVELERAKTRAPDTEQSRAVEAQLMEAKKKTFLLETTKIDGKSLKDVIDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6P5</accession>
    <name>A4S6P5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17885</name>
        <name evidence="3" type="ORF">OSTLU_19223</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421125.1">
        <property type="nucleotide sequence ID" value="XM_001421088.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422829.1">
        <property type="nucleotide sequence ID" value="XM_001422792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6P5"/>
    <dbReference type="GeneID" id="5004981"/>
    <dbReference type="GeneID" id="5006969"/>
    <dbReference type="Gramene" id="ABO99418">
        <property type="protein sequence ID" value="ABO99418"/>
        <property type="gene ID" value="OSTLU_17885"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01188">
        <property type="protein sequence ID" value="ABP01188"/>
        <property type="gene ID" value="OSTLU_19223"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17885"/>
    <dbReference type="KEGG" id="olu:OSTLU_19223"/>
    <dbReference type="HOGENOM" id="CLU_895422_0_0_1"/>
    <dbReference type="OrthoDB" id="501718at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="311" mass="33061" checksum="8E7AE2D9D3072E0F" modified="2007-05-15" version="1">MPPRPRADASVDLARARASADDVSHRLSDTRARTVQAVELTERALREFRDADARDASKPRSTLVSPYDGEEDEEGGDNELTALVRQLESFAEKRTGTGQAPRGANGTSGTTRGERERERERGGDKWSVKSGDSGDGRSMNDENSLVGYSMMYGSTVDDDGSAADADELASEFSVDFSLPSERVAGGATARNDKKSELGSVSGRINAVSDSLTTSKSRLHESIASLELEAGLTENGAEMDFEQYKDDMPVVGNTKTGQVVIDLAARGVNSLSRSSSQFMGEGKGGRGGDGAELSPLVRMFNSVCGGCCALRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6R7</accession>
    <name>A4S6R7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ZIP family transporter: zinc ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_25431</name>
        <name evidence="8" type="ORF">OSTLU_29694</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420991.1">
        <property type="nucleotide sequence ID" value="XM_001420954.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422904.1">
        <property type="nucleotide sequence ID" value="XM_001422867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6R7"/>
    <dbReference type="GeneID" id="5004996"/>
    <dbReference type="GeneID" id="5006874"/>
    <dbReference type="Gramene" id="ABO99284">
        <property type="protein sequence ID" value="ABO99284"/>
        <property type="gene ID" value="OSTLU_25431"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01263">
        <property type="protein sequence ID" value="ABP01263"/>
        <property type="gene ID" value="OSTLU_29694"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25431"/>
    <dbReference type="KEGG" id="olu:OSTLU_29694"/>
    <dbReference type="eggNOG" id="KOG2693">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025421_0_0_1"/>
    <dbReference type="OMA" id="LMAYFID"/>
    <dbReference type="OrthoDB" id="46759at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007635074" evidence="6">
        <location>
            <begin position="20"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP01263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="477" mass="50636" checksum="48B53E435BFC7F06" modified="2007-05-15" version="1">MRCASALGGGIAIVASALAQRGAHASGAHAFEWAGIFETPENEYVWQAQKVADKYAADTMKMVIYDEIAAGHDELEAREDSGDTAIGGACTTAKIRDSVLTPDSGCVNLEFDNTWHTTPFKINTTGIDAISIFAEHVPTEFERDAHYLKDLHGDDVVPKASLPEASTVSESKSKPWANAIGAAIIVNIVTLSGVVFLIPSIAKKQKAYPETVSCTINSFAAGALLSAAFYLMFYEATHLIKPAGSDEAEQTAWWASASIFGFLMAYFIDFGISVVFPTLGNTAKTTDAELAVKGAQDDCDTCTCNSHKYRVRSGIILGDFMHNLVDGIFIGFGFLNCDSTMGWSITAATVYHEIAQELADYLVLVDPFQGDLAPLPTLTLNFVSGLSVILGVLISVGSGNNNDFWHGLLLAFGAGVYLQIAAAECMPRVSVSATSPRLRATSILTFIVGVVAISLVLLNHKHCTGGGGGGDSHAHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6S0</accession>
    <name>A4S6S0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_47300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420992.1">
        <property type="nucleotide sequence ID" value="XM_001420955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6S0"/>
    <dbReference type="STRING" id="436017.A4S6S0"/>
    <dbReference type="GeneID" id="5004998"/>
    <dbReference type="Gramene" id="ABO99285">
        <property type="protein sequence ID" value="ABO99285"/>
        <property type="gene ID" value="OSTLU_47300"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_47300"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_5_1"/>
    <dbReference type="OMA" id="ASICIRC"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010291">
        <property type="term" value="F:beta-carotene 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016123">
        <property type="term" value="P:xanthophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11046">
        <property type="entry name" value="CYP97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF171">
        <property type="entry name" value="PROTEIN LUTEIN DEFICIENT 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="2">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="55796" checksum="5B72BB8B9BBE95D4" modified="2007-05-15" version="1" fragment="single">MPVASGDIREIAGQPVFVPLYKLFLAYGEMFVLAIGPKKFVVVSDNAVAKEMLLTQAKSFSKGLLSEILDFVMGQGLIPANGEVWKIRRKVIVPSLHKKYVTSMVDMFGDCGLKGMSQLARAEKANESVEMENFYSRFALDIIGKAVFNYDFDSLSTDDPVIKAVYTVLREAEYRSVTFIPYWKVPPLRWLVPRQRQCQEALQVVNDTLDDLINRCKAVVEEEDEEFVEEYMNTDDPSILHFLIASGDDVTSKQLRDDLMTLLIAGHETTAAVLTWTTFLLAKHPEVKAKVFEEVDRVVGDRNPTVADMRALVYTTRVINESMRLYPQPPVLIRRALEPVTLGGYNIDAGTDFFISVWNLHRNPRIWDEPDAFKPERFPIDAPMPNEYTEEYAYLPFGGGQRKCVGDQFAIFESIVSLAMLMRRFDFELDESKHPDGECGMTTGATIHTTNGLHVKLKRRDGRGGREMDGTYVTGMALSNLEDVDVVRGSIDAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6U5</accession>
    <name>A4S6U5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29666</name>
        <name evidence="2" type="ORF">OSTLU_93639</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421004.1">
        <property type="nucleotide sequence ID" value="XM_001420967.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422891.1">
        <property type="nucleotide sequence ID" value="XM_001422854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6U5"/>
    <dbReference type="GeneID" id="5005011"/>
    <dbReference type="GeneID" id="5006859"/>
    <dbReference type="Gramene" id="ABO99297">
        <property type="protein sequence ID" value="ABO99297"/>
        <property type="gene ID" value="OSTLU_93639"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01250">
        <property type="protein sequence ID" value="ABP01250"/>
        <property type="gene ID" value="OSTLU_29666"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29666"/>
    <dbReference type="KEGG" id="olu:OSTLU_93639"/>
    <dbReference type="eggNOG" id="KOG2793">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_977751_0_0_1"/>
    <dbReference type="OMA" id="HHNPEEV"/>
    <dbReference type="OrthoDB" id="513683at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="281" mass="30411" checksum="4EEBFBF0CAE5D6C4" modified="2007-05-15" version="1">MASTWRRNRLSFREKFVDACDVDGVVVRQYASSEAFVKATGTTGTTGTTTRDDDDDDDDDDAVPATGFTVWDASVLLGKYVGRERTWRRLTKKAREDARGPTTLELGAGTGLATLLVAAARGSAEGEAGMVCAMTDLKRVVPLTRMNARANKAESGGRIPASVAMATTTLRWGRAEDVERLPEAIRRPDVVLGADLMYTSDEGVIRALAATTMALVGPGRAAVFAACKEHRPESVELFASIIEANGFEVTRVPASEAHPDYPASNEEFELLECWRPRPRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6U7</accession>
    <name>A4S6U7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_36774</name>
        <name evidence="3" type="ORF">OSTLU_51291</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421005.1">
        <property type="nucleotide sequence ID" value="XM_001420968.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422890.1">
        <property type="nucleotide sequence ID" value="XM_001422853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6U7"/>
    <dbReference type="GeneID" id="5005012"/>
    <dbReference type="GeneID" id="5006858"/>
    <dbReference type="Gramene" id="ABO99298">
        <property type="protein sequence ID" value="ABO99298"/>
        <property type="gene ID" value="OSTLU_51291"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01249">
        <property type="protein sequence ID" value="ABP01249"/>
        <property type="gene ID" value="OSTLU_36774"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36774"/>
    <dbReference type="KEGG" id="olu:OSTLU_51291"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_6_3_1"/>
    <dbReference type="OMA" id="SCCSEDC"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="157"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="300" mass="33304" checksum="3C54D46E8FE02F4A" modified="2007-05-15" version="1">MTRIPTINLARDGSARGLTDAFASDDFARRGFAFVAHEGALPEPEIVRKCFAESRTFFDSSDETRKRALTGDAPGIGYTAFASEKLDPSSSSVGDSKEGFYVVRERAKNRWPSAAFEDAATTYYESMYALGKRLLPALARACGVNDAYFDAHWSASSHNCVLRFLKYSASRSDEGEGQFACGAHTDYGALTILAVENDGSTGLEIYDRETETWVPVTPPPDHFVLNVGDLLERWSNGRFASTRHRVMTTGERERFSIPFFFEPSYDAVIEPVCVGDGEAAKYAPIRFGDYLQEKYAQTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6X0</accession>
    <name>A4S6X0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17941</name>
        <name evidence="4" type="ORF">OSTLU_19169</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421016.1">
        <property type="nucleotide sequence ID" value="XM_001420979.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422879.1">
        <property type="nucleotide sequence ID" value="XM_001422842.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S6X0"/>
    <dbReference type="GeneID" id="5004939"/>
    <dbReference type="GeneID" id="5006937"/>
    <dbReference type="Gramene" id="ABO99309">
        <property type="protein sequence ID" value="ABO99309"/>
        <property type="gene ID" value="OSTLU_17941"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01238">
        <property type="protein sequence ID" value="ABP01238"/>
        <property type="gene ID" value="OSTLU_19169"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17941"/>
    <dbReference type="KEGG" id="olu:OSTLU_19169"/>
    <dbReference type="eggNOG" id="KOG0939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_226044_0_0_1"/>
    <dbReference type="OMA" id="DANDGHE"/>
    <dbReference type="OrthoDB" id="515428at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="CDD" id="cd14327">
        <property type="entry name" value="UBA_atUPL1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010314">
        <property type="entry name" value="E3_Ub_ligase_DUF913"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06025">
        <property type="entry name" value="DUF913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="1199"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1179"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1244"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1930"/>
            <end position="2124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2162"/>
            <end position="2207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2506"/>
            <end position="2525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1959"/>
            <end position="1969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1970"/>
            <end position="1986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1993"/>
            <end position="2006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2007"/>
            <end position="2028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2049"/>
            <end position="2086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2087"/>
            <end position="2098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2111"/>
            <end position="2124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2172"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="3018"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="3018" mass="333270" checksum="3D9EAD3D718D39F7" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S743</accession>
    <name>A4S743_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">TRAF-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_89070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
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                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
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    </dbReference>
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            <end position="72"/>
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            <position position="1"/>
        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99681.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="572" mass="63552" checksum="8AEC0C553D94C2F9" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
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    <accession>A4S754</accession>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
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                <person name="Paulsen I."/>
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                <person name="Van de Peer Y."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
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        <property type="entry name" value="Homeodomain-like_sf"/>
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    </dbReference>
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        <property type="entry name" value="SANT/Myb"/>
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        <property type="entry name" value="MYB-LIKE DNA-BINDING DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
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    </dbReference>
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        <property type="entry name" value="MYB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SANT"/>
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            <end position="354"/>
        </location>
    </feature>
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        <location>
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            <end position="350"/>
        </location>
    </feature>
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        <location>
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            <end position="493"/>
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    </feature>
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        <location>
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            <end position="489"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
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            <end position="403"/>
        </location>
    </feature>
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        <location>
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            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S796</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Jorgensen R."/>
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                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
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                <person name="Robbens S."/>
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            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
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        <text evidence="3">Component of the large ribosomal subunit (LSU).</text>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:adaxial/abaxial pattern specification"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="7">
        <location>
            <begin position="243"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="300" mass="34044" checksum="0277C3FB69190994" modified="2007-05-15" version="1">MGRRKVKRKSQSVAKTNAYFSRFQVKFARRRAGKTDYYARQRLITQDKNKYNSPKYRFVVRFTNRDVICQVVYATLAGDVCIASAYSHELPKYGMKAGLTNYAATYATGLLCARRLLTKYGLADAYEGKTEDLGEDYHVEQGDEEARPFKCFLDTGLVRTSTGARVFAALKGAVDGGLDIPHNEKRFAGYDLQDKSHDPDTLERYIKGGVVAEYAEELQEEEPEKFEQQFAKYLAADFDPTELEDAMEDVLDAIREDPVHEKKERVKPADAGRLFKLPKLTYEEKKANLKAKLEALRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7C4</accession>
    <name>A4S7C4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27510</name>
        <name evidence="3" type="ORF">OSTLU_93682</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421249.1">
        <property type="nucleotide sequence ID" value="XM_001421212.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421285.1">
        <property type="nucleotide sequence ID" value="XM_001421248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7C4"/>
    <dbReference type="STRING" id="436017.A4S7C4"/>
    <dbReference type="GeneID" id="5005331"/>
    <dbReference type="GeneID" id="5005516"/>
    <dbReference type="Gramene" id="ABO99542">
        <property type="protein sequence ID" value="ABO99542"/>
        <property type="gene ID" value="OSTLU_93682"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99578">
        <property type="protein sequence ID" value="ABO99578"/>
        <property type="gene ID" value="OSTLU_27510"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27510"/>
    <dbReference type="KEGG" id="olu:OSTLU_93682"/>
    <dbReference type="eggNOG" id="ENOG502QW1K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_981373_0_0_1"/>
    <dbReference type="OMA" id="SHFATEM"/>
    <dbReference type="OrthoDB" id="20822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="2">
        <location>
            <begin position="77"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="31695" checksum="94E37CD7954056F5" modified="2007-05-15" version="1">MSMTFETREACDADRIVEALARVVVDDGALGAEGETPSDFEARVTTMKADVAAQLDEAKKMYEERARTGGAPRRLTLREMDRKMSFRDVANAVRADAGAFNWYLVRGDANGASEVFNAGGGSLDEMKKSLASDEVFFGLLRMGFGRGAFRRVKHIFIHWSGADVNPLKRGQHNANEEAIRKLVGPVNLSHFATEMDEMNLNDLLDKVKTKVVLDGEAIDDVEDLFSLESYMVSCEDDAEAMKREFPDAIREGDGEEDEQEPTFEEALESVRDKSQPYNWMLCTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7W5</accession>
    <name>A4S7W5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MOSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421346.1">
        <property type="nucleotide sequence ID" value="XM_001421309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7W5"/>
    <dbReference type="STRING" id="436017.A4S7W5"/>
    <dbReference type="GeneID" id="5005241"/>
    <dbReference type="Gramene" id="ABO99639">
        <property type="protein sequence ID" value="ABO99639"/>
        <property type="gene ID" value="OSTLU_18206"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18206"/>
    <dbReference type="eggNOG" id="KOG2362">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028286_0_1_1"/>
    <dbReference type="OMA" id="ARQYPQM"/>
    <dbReference type="OrthoDB" id="17255at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="169"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="36970" checksum="8DF16471B40B4D3C" modified="2007-05-15" version="1">MSPKITELCSYPVKSCAGVSLDACALTSTGLAFDRLFCVVNAVDGKFISQRSHPRLSLVACAIEPPDAFTDRTVRQFALTCETSSMATKLRVEVDLDDASGTATSATNVECWEWRGKAAKCGDEAGRWFSEFLNQTPDGDGAAYELVRWMGKGGAPSAPQDADDLDVDDDVTRLTSENYGSRRATTTLSDGYPMLLVNAASVRAMHELVREETEKSNAAPVVVDNRRFRGNVVVDDAKAYAEDTWSVIALGAREVQAELCKPCSRCSIPLVDPDVGSPALGAPLARALSRARSGAALRTANRLWRQSPFFGWNLLVPSTQDATVVLRVGDDVRVLETRPAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Y2</accession>
    <name>A4S7Y2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421529.1">
        <property type="nucleotide sequence ID" value="XM_001421492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Y2"/>
    <dbReference type="STRING" id="436017.A4S7Y2"/>
    <dbReference type="GeneID" id="5005441"/>
    <dbReference type="Gramene" id="ABO99822">
        <property type="protein sequence ID" value="ABO99822"/>
        <property type="gene ID" value="OSTLU_27659"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27659"/>
    <dbReference type="HOGENOM" id="CLU_1236508_0_0_1"/>
    <dbReference type="OMA" id="CAREAMG"/>
    <dbReference type="OrthoDB" id="286637at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032182">
        <property type="term" value="F:ubiquitin-like protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014764">
        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281:SF31">
        <property type="entry name" value="DCN1-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCUN1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="225" mass="25176" checksum="C78A32DD8F5EA61F" modified="2007-05-15" version="1">MRAPTIDERVARCVECVETGDDDAEARYEFCYAVMRERGARHCSREAATACWRETFARERDATTRDAMDDGEGGARANANDVVDAFVSYVRDRRDVTVITADAWSQAYQFVRRARALGGDLRWYDENEAWPSLFDEFVECAREAMGSAAMRAETTASGRGDDARRVDAFSSMAFASATESRKRRVEHVAEARANVVGLTREFERELAVGGRAPKRVCSDMDLGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8A3</accession>
    <name>A4S8A3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="2">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_27778</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421731.1">
        <property type="nucleotide sequence ID" value="XM_001421694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8A3"/>
    <dbReference type="STRING" id="436017.A4S8A3"/>
    <dbReference type="GeneID" id="5005626"/>
    <dbReference type="Gramene" id="ABP00025">
        <property type="protein sequence ID" value="ABP00025"/>
        <property type="gene ID" value="OSTLU_27778"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27778"/>
    <dbReference type="eggNOG" id="KOG1622">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_0_5_1"/>
    <dbReference type="OMA" id="IWQSFAV"/>
    <dbReference type="OrthoDB" id="1724632at2759"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000002">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="15">
        <location>
            <begin position="220"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="248"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABP00025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="547" mass="60382" checksum="05C6520746D1D20E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8U4</accession>
    <name>A4S8U4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421951.1">
        <property type="nucleotide sequence ID" value="XM_001421914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8U4"/>
    <dbReference type="STRING" id="436017.A4S8U4"/>
    <dbReference type="GeneID" id="5006109"/>
    <dbReference type="Gramene" id="ABP00245">
        <property type="protein sequence ID" value="ABP00245"/>
        <property type="gene ID" value="OSTLU_18450"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18450"/>
    <dbReference type="HOGENOM" id="CLU_843049_0_0_1"/>
    <dbReference type="OMA" id="NECTIER"/>
    <dbReference type="OrthoDB" id="4348522at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="36635" checksum="05829FEDF94AD16A" modified="2007-05-15" version="1">MREALDAIETLKREKDAIGRRATESDDARRALEKAKNELSAIRLAQDTLASKVRRDAREMKTLREKNDELTRSLSKFEDKERIEREVAASASSLGEREMLKRLEGSDPRLAMTTLVRNLCAKNKQIASQQEQYDALARKVREKEKDVKALEAKLDAFRDVAKTQTAAKPKPAAPAPPTSTGDFQLGGRANSRHAWGVDDPSEFAYPPTQRVADKKRVVKKSLRRGDDELMKKLAPPPPKRTSNRDEINLVSDDDDDGVEDDVLANILNDVDARVERKRQKMAASGSAATNKTRRAGSFLKSSPRAPSNSNGTFIKHGADGRGGRGKFFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S912</accession>
    <name>A4S912_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421853.1">
        <property type="nucleotide sequence ID" value="XM_001421816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S912"/>
    <dbReference type="STRING" id="436017.A4S912"/>
    <dbReference type="GeneID" id="5006025"/>
    <dbReference type="Gramene" id="ABP00147">
        <property type="protein sequence ID" value="ABP00147"/>
        <property type="gene ID" value="OSTLU_93851"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93851"/>
    <dbReference type="eggNOG" id="ENOG502SH30">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1799016_0_0_1"/>
    <dbReference type="OMA" id="HHKLRRP"/>
    <dbReference type="OrthoDB" id="496984at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="113"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="146" mass="16709" checksum="DDF31C90DADC7267" modified="2007-05-15" version="1">MEKHHKLRRPQGSSIHGCNICGIEGHQAAFCMNGNVDWANRWPRECFVIEPPQSAPKARKEPDFRKMAREAKAYAKKKMRKEEREKRRAAGEEVSESEEEPAKTETATGGAKGAMVEGWVMYYDKLGRPYYHNKLTNKTQWTAPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9P4</accession>
    <name>A4S9P4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Plastid ribosomal protein L15 large ribosomal subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PRPL15</name>
        <name evidence="7" type="ORF">OSTLU_28269</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422103.1">
        <property type="nucleotide sequence ID" value="XM_001422066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9P4"/>
    <dbReference type="STRING" id="436017.A4S9P4"/>
    <dbReference type="GeneID" id="5006263"/>
    <dbReference type="Gramene" id="ABP00420">
        <property type="protein sequence ID" value="ABP00420"/>
        <property type="gene ID" value="OSTLU_28269"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28269"/>
    <dbReference type="eggNOG" id="KOG0846">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055188_0_0_1"/>
    <dbReference type="OMA" id="MRGQNAR"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="127"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="222" mass="23032" checksum="5382E6DB46B48FDC" modified="2007-05-15" version="1">MSITALTNTVSALSLSSRGNARGTFRVRAVRPTKSFSSAVVASDDERLRLHNLSPLKGSRREKKRIGRGYGAGQGGSCGDGMRGQRARSGPGVRPGFEGGQTPMYRRFPKLKGIAGGMGAGKPKFVTVNVGDLEAAVQAKKLDASAEITIEALKSAGVIKATGYYRNLPLKVLGEGEVSGLKVKAASFSQSASEKLTAAGGAAEVLPAKEKWSRQAAAAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9P6</accession>
    <name>A4S9P6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_28271</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422104.1">
        <property type="nucleotide sequence ID" value="XM_001422067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9P6"/>
    <dbReference type="STRING" id="436017.A4S9P6"/>
    <dbReference type="GeneID" id="5006264"/>
    <dbReference type="Gramene" id="ABP00421">
        <property type="protein sequence ID" value="ABP00421"/>
        <property type="gene ID" value="OSTLU_28271"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28271"/>
    <dbReference type="eggNOG" id="KOG2979">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1121414_0_0_1"/>
    <dbReference type="OMA" id="RREYECA"/>
    <dbReference type="OrthoDB" id="511386at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11789">
        <property type="entry name" value="zf-Nse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="11">
        <location>
            <begin position="145"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="230" mass="25609" checksum="50C445FB0C9E4D79" modified="2007-05-15" version="1">MSASPRLSAVRLAASVEARIDETRESIEHVRIACEAATEAARIAERDARGSSKALRAKVEALCELKREKLARVDALEALRREYECAATTEFNFEEYLTKKTKHYASKRRQELEYLIAFDEAVRGVDGDDLDADLVLDEEDGTAGARNAKCPLTAKRIEAIDEPVEDKMGFIYEKDAIMRYIGSKKSVDCPEAGTRHKVSKADLKPSRTALKMKQRAEGLDEDDSGQLLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Z2</accession>
    <name>A4S9Z2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422255.1">
        <property type="nucleotide sequence ID" value="XM_001422218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9Z2"/>
    <dbReference type="STRING" id="436017.A4S9Z2"/>
    <dbReference type="GeneID" id="5006210"/>
    <dbReference type="Gramene" id="ABP00572">
        <property type="protein sequence ID" value="ABP00572"/>
        <property type="gene ID" value="OSTLU_93957"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93957"/>
    <dbReference type="eggNOG" id="KOG2859">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059815_1_0_1"/>
    <dbReference type="OMA" id="DNIAAFY"/>
    <dbReference type="OrthoDB" id="420422at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19490">
        <property type="entry name" value="XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030547">
        <property type="entry name" value="XRCC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46644">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46644:SF2">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="332" mass="36464" checksum="9FE8765E20599DAD" modified="2007-05-15" version="1">MNTLEETLAFLAPSETARAYLDRALREPLRSGIPFVDARDPEPALRAGEIVEIVGAPGSGKTEFVTEIAAHAVLPRARDGVRYDGSEARVIVIDCDGKFDQLRLLRALNRKIEEKLANVRENQRVTMRDEVYEESMSRFTLVRAHGMVDALKTLTALDAAWSGAIESAKRDGLFVDAETAETRETGEDAEGGGTNGAKSGEMAKFASQRLVICDNVAAFYWLDRASRKDHGAPFNIQRVFSAAARLFKRLASAHRAAVVVTKTTLSSNDGRRGGQYKDFLPVEWTNAVTQRVLLAPSNKRVGYGEYAGVATWDVPVRRHGGAYTVTEEGMRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA91</accession>
    <name>A4SA91_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422343.1">
        <property type="nucleotide sequence ID" value="XM_001422306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA91"/>
    <dbReference type="GeneID" id="5006374"/>
    <dbReference type="Gramene" id="ABP00660">
        <property type="protein sequence ID" value="ABP00660"/>
        <property type="gene ID" value="OSTLU_25786"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25786"/>
    <dbReference type="HOGENOM" id="CLU_750971_0_0_1"/>
    <dbReference type="OrthoDB" id="10036559at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052514">
        <property type="entry name" value="SAM-dependent_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203">
        <property type="entry name" value="METHYLTRANSFERASE, FKBM FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203:SF15">
        <property type="entry name" value="SLL1173 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673153" description="Methyltransferase FkbM domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="136"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="369" mass="41627" checksum="FE424D3AD4A5055B" modified="2007-05-15" version="1">MQSLQVSVRAKHTLLLSLFIIPTLLRRGVNYSVSASPEQEVVFTPRHTNISEITLNGVEDTHTLVKDKADVKTEVYGYVNLPIVLKREDTFEWLPVNGGELKIQQILRNLLASTPVEYKSNAISSVSRGRGATINIGAHECFFCVIFMLSGYRVYAVEPLPLCVSGIQETFSLYPRQFVRRVSLYNNYVSDVPIAIDTPINTCSGTFHTHAEGVGAGHKIVSSIALDDIPLNDDDVEILAIDTEGNELSVLSSGMRIFRTKTVKNVFFEYTAVWYRERTSFSLHRAIELMEEIIRLQGYKCYLLLDFVESISDTEELDIGARLERDWNAKTTDNQTDIYCTRCKHWLKVNPLHDASAKAQVTELCSTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA95</accession>
    <name>A4SA95_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422302.1">
        <property type="nucleotide sequence ID" value="XM_001422265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA95"/>
    <dbReference type="GeneID" id="5006403"/>
    <dbReference type="Gramene" id="ABP00619">
        <property type="protein sequence ID" value="ABP00619"/>
        <property type="gene ID" value="OSTLU_25788"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25788"/>
    <dbReference type="HOGENOM" id="CLU_800214_0_0_1"/>
    <dbReference type="OMA" id="YREWFYT"/>
    <dbReference type="OrthoDB" id="10432211at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671956" description="Nucleotide-diphospho-sugar transferase domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="38141" checksum="EC9FC077654BE6EA" modified="2007-05-15" version="1">MGSRKQRVAVVLALVALVAGGGLVKQLDTRGCSKDTSAATVSGASSSAQPRSTGAESRDNKRETPPIDAVSATKIDDRAEKYAIIVPMHAVTQLEVMKTTWKIFPPCAADARAAQIIDLIFLSDVDLSSLDVTGGHCFQRVYRLRPFIPSCYNVYAQAPPYCFFTMILHLDLDRTYDAILQVEADSVPVKSNWLDAAVENILKPTSGEVWIHAAKNERGGNNFNGNGAYNLQNDEFRQFIIGYREWFYTKAVNSGDTAFDTNMITFAKEVGSFGNFSNTHLRASKSLRNCDLMSLTACRSAVDASTWGGATPEALFVHSHDLKDPSRVRSQILVEMLGRDDGIRQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBE4</accession>
    <name>A4SBE4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-5-taurinomethyluridine 2-sulfurtransferase</fullName>
            <ecNumber evidence="3">2.8.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_43910</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP = 5-taurinomethyl-2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47040"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11732"/>
            <dbReference type="Rhea" id="RHEA-COMP:11733"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:87171"/>
            <dbReference type="ChEBI" id="CHEBI:87172"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422602.1">
        <property type="nucleotide sequence ID" value="XM_001422565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBE4"/>
    <dbReference type="STRING" id="436017.A4SBE4"/>
    <dbReference type="GeneID" id="5006660"/>
    <dbReference type="Gramene" id="ABP00919">
        <property type="protein sequence ID" value="ABP00919"/>
        <property type="gene ID" value="OSTLU_43910"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43910"/>
    <dbReference type="eggNOG" id="KOG2805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035188_1_0_1"/>
    <dbReference type="OMA" id="LFMRNWN"/>
    <dbReference type="OrthoDB" id="3685at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061708">
        <property type="term" value="F:tRNA-5-taurinomethyluridine 2-sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="MnmA_TRMU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="MnmA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046885">
        <property type="entry name" value="MnmA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046884">
        <property type="entry name" value="MnmA-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="MnmA-like_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001138">
        <property type="entry name" value="PRK00143.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933:SF5">
        <property type="entry name" value="MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933">
        <property type="entry name" value="TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20258">
        <property type="entry name" value="tRNA_Me_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20259">
        <property type="entry name" value="tRNA_Me_trans_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA-specific 2-thiouridylase MnmA-like central" evidence="13">
        <location>
            <begin position="221"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-specific 2-thiouridylase MnmA-like C-terminal" evidence="12">
        <location>
            <begin position="307"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABP00919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="389" mass="42274" checksum="9C2772EE3E5FB1C4" modified="2007-05-15" version="1">MPARSEAATAGAREEYVVGLSGGVDSAVAAWALERCGARATATLMRNWDARDEDAATDCSHRDDLKSARAIAEKLNLRFIESDFTREYWHEVFEPYVEAFESGATPNPDLECNRRVKFGALLRRAMEDLGGRYLATGHYARIDRDVDEGAPPRLLRGIDQTKDQSYFLASVRGEALRSACFPLGAVFKSETREAARILGFDCADRRSSAGICFIGRRPFGEFIGEYITPSEGAFVDAETARPVPGAAPHRGLASYTVGQRAKIGGAPKPWFVVGKNVAANVVYVAKGAEHDALYSTRAALADEFWISNRRPTSDDGSSSVRLLAKTRYASFSSSFVPRVESSPLRATFDRPERAVTPGQALVLYDGDVCLGGGVIEHVGVTEFEARAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQF2</accession>
    <name>A4RQF2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_40103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415724.1">
        <property type="nucleotide sequence ID" value="XM_001415687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQF2"/>
    <dbReference type="STRING" id="436017.A4RQF2"/>
    <dbReference type="GeneID" id="4999499"/>
    <dbReference type="Gramene" id="ABO94016">
        <property type="protein sequence ID" value="ABO94016"/>
        <property type="gene ID" value="OSTLU_40103"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40103"/>
    <dbReference type="eggNOG" id="KOG1469">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007526_0_1_1"/>
    <dbReference type="OMA" id="MCVYRHP"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF3">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="264" mass="29235" checksum="42E98AA541EA9E3E" modified="2007-05-15" version="1" fragment="single">MGKCRHPIDETALLRFCRARVPGFPRACASLDVDQFAHGQSNPTYKILALTRRGDVCGTYVVRKKPAGTLLKSAHAVEREYAVMRALRTTNVPTPDALALCEDARVLGEAFYVMSYVDGDIYLQPRMEECSERRRGAVYEKMARTLGTLHAVDPRAVGLGDFGKAERYGERQTERWAKQYEASVGPGVGVHAEESMMTLIAWLRSNAPAKEISGRLVHGDFRLDNLVLSRARSNGDDQVDVLAVLDWELSTLGAPYADVAFNCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQU0</accession>
    <name>A4RQU0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415793.1">
        <property type="nucleotide sequence ID" value="XM_001415756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQU0"/>
    <dbReference type="GeneID" id="4999872"/>
    <dbReference type="Gramene" id="ABO94085">
        <property type="protein sequence ID" value="ABO94085"/>
        <property type="gene ID" value="OSTLU_28778"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28778"/>
    <dbReference type="eggNOG" id="KOG4567">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018687_0_1_1"/>
    <dbReference type="OMA" id="WLNSPMW"/>
    <dbReference type="OrthoDB" id="10263206at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF27">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="27"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="318" mass="35836" checksum="874F135C48F06ABA" modified="2007-05-15" version="1">MEALGRDDEVDAGRLKLLASDGGVPDDDGGRARAMVWKVCLEYLPKERARWEATERARREEYGRFLEEFCASTTTTTTSGAWIDARRGDELAEQIDRDVARVHPDMHFFNDEGEDGEGGRRKDEMRNALYVFAKLNPGVGYVQGMHEMYGCIYYVLANSADAHAAPNAAAADAFYCFTEIFGEFRDVFVMELDATDQGVRALLDELSDMLAVHGPEVHGHLEDLNLTTSMYAFRWITLLFTQDFEFADVLRLWDVMLASPRSRKECLLRLCVACVLNIGSELIDGDFATCMKMLQNYPPVDIRRITRLAAALPYGIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR31</accession>
    <name>A4RR31_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">GPI transamidase component PIG-S</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_28873</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415830.1">
        <property type="nucleotide sequence ID" value="XM_001415793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR31"/>
    <dbReference type="STRING" id="436017.A4RR31"/>
    <dbReference type="GeneID" id="5000056"/>
    <dbReference type="Gramene" id="ABO94122">
        <property type="protein sequence ID" value="ABO94122"/>
        <property type="gene ID" value="OSTLU_28873"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28873"/>
    <dbReference type="eggNOG" id="KOG2459">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010026_4_1_1"/>
    <dbReference type="OMA" id="VPVCFPI"/>
    <dbReference type="OrthoDB" id="28748at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019540">
        <property type="entry name" value="PtdIno-glycan_biosynth_class_S"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072:SF13">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10510">
        <property type="entry name" value="PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="48837" checksum="3790B41E309DF30B" modified="2007-05-15" version="1">MDALAAASDEDVDARTRALADENATVYDFVVVRDRRGENDEERGKFVVGTHRAAWMRFDDERLLADELEERLRALFAPADETTPSASPFLTTSDGILLASFSLVNAEPTPGYAFSWDFQRDVEQPFLGALPEALSRVLEVRIEAQVLRHARSRVRPMWSDKHRGYVVDSKQTPFFIDSDWPIDTSVTYTPIDGKPLHFVVYVPPQTECPLYVLDDNHELTATNAFIVEGWGGLVVVNPPGCAVARGENEIRLRNDEVVNVVNAFVRQLRIHLGAGEFLQKFGAKVLPPKHTGFATWEVDALVHSRLVADSQSTISTLKSLDEVISSIADIAVPDAIAERILESVEALERAIDLAQNARYDEAGASARSAHAAAERAFFDPFSLGGLESFPFEYKVASVMPIILPTIFPLMLGFMREMRHFQLRRREAFRASESSKKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR58</accession>
    <name>A4RR58_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Condensin complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CPH3501</name>
        <name evidence="12" type="ORF">OSTLU_40141</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CND2 (condensin subunit 2) family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO93807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415478.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RR58"/>
    <dbReference type="GeneID" id="4999388"/>
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        <property type="protein sequence ID" value="ABO93807"/>
        <property type="gene ID" value="OSTLU_40141"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40141"/>
    <dbReference type="eggNOG" id="KOG2328">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_010510_1_0_1"/>
    <dbReference type="OMA" id="FRKTCAD"/>
    <dbReference type="OrthoDB" id="362021at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022816">
        <property type="entry name" value="Condensin_barren_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108:SF9">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05786">
        <property type="entry name" value="Cnd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017126">
        <property type="entry name" value="Condensin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="155"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="344"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="407"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO93807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="657" mass="71306" checksum="5A1ABE214AB88BAA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRB3</accession>
    <name>A4RRB3_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4RRB3"/>
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        <property type="protein sequence ID" value="ABO93834"/>
        <property type="gene ID" value="OSTLU_28955"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502QUTY">
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF20">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="259" mass="27300" checksum="49974BE52BF6AA8C" modified="2007-05-15" version="1">MFALAPAFAPRAPASGAPRASGARRVVVARAAAPSPSSSSSSRRVALALASSLAAFLRPRASDAAYGTSAGGSSDTDASDLTWGTFYGAANPPATYGTTGGTTKSLAKYSYDVPSSWVEEATTKVEKGSGGQDSRWVKRGSRGEEKAYLLTLNRAGQDGAAFELTDASLQAVAGALSEMQDSIASGRVTSRRDTEDGREYALFDVDADRKYTVKISIDNTGRLFAFVVTAPASQFNRDKKVLDRMVDSFRIYTSASQFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRE0</accession>
    <name>A4RRE0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAC3/GANP/THP3 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ABO93845"/>
        <property type="gene ID" value="OSTLU_28983"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28983"/>
    <dbReference type="eggNOG" id="KOG1860">
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    </dbReference>
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    <dbReference type="OrthoDB" id="264795at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="394"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="809"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1556" mass="164598" checksum="3DEBD88045FD7B33" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRF6</accession>
    <name>A4RRF6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415892.1">
        <property type="nucleotide sequence ID" value="XM_001415855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRF6"/>
    <dbReference type="GeneID" id="4999555"/>
    <dbReference type="Gramene" id="ABO94184">
        <property type="protein sequence ID" value="ABO94184"/>
        <property type="gene ID" value="OSTLU_29000"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29000"/>
    <dbReference type="HOGENOM" id="CLU_1962510_0_0_1"/>
    <dbReference type="OMA" id="TFADRWM"/>
    <dbReference type="OrthoDB" id="10532723at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="141" mass="15142" checksum="61821B8D0FAD4988" modified="2007-05-15" version="1">MFRDLASKLYSARGPASTTTRRDDADASRRRAASAPRGSTADAADDASRAPSTFADRWMMSWTDEDVTFLGEDPYGDCAGNVFAAAAAEARRRRASVDETREPRASGDEDAASRRASMDDARGATASAEAKARAFWRIGPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRM3</accession>
    <name>A4RRM3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 28 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29067</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the VPS28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415594.1">
        <property type="nucleotide sequence ID" value="XM_001415557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRM3"/>
    <dbReference type="STRING" id="436017.A4RRM3"/>
    <dbReference type="GeneID" id="4999724"/>
    <dbReference type="Gramene" id="ABO93886">
        <property type="protein sequence ID" value="ABO93886"/>
        <property type="gene ID" value="OSTLU_29067"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29067"/>
    <dbReference type="eggNOG" id="KOG3284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076417_1_0_1"/>
    <dbReference type="OMA" id="CDEFPTV"/>
    <dbReference type="OrthoDB" id="2671at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="7">
        <location>
            <begin position="121"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO93886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="24382" checksum="8FAF9D68ACCA09FB" modified="2007-05-15" version="1">MPPARDVADGECVRLWRTTDERKRYDDFATLYALARALEKLERAYVRSSVDAKAYERACVDLTSKFKTLRSVLRDSVPDLDRFLETYGARVPAARRRLEAGVPATAEHGGAARGTEAEGRAEARAVADATHCFIGVMDTVKLDMRAKDQVAPALGDLLLALCKVSRLPNDFEGTKCVRKWVLRLDEMRASEVLEEEETREFLYEIENAYSTFLASLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRZ2</accession>
    <name>A4RRZ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_10299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415650.1">
        <property type="nucleotide sequence ID" value="XM_001415613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRZ2"/>
    <dbReference type="STRING" id="436017.A4RRZ2"/>
    <dbReference type="GeneID" id="4999762"/>
    <dbReference type="Gramene" id="ABO93942">
        <property type="protein sequence ID" value="ABO93942"/>
        <property type="gene ID" value="OSTLU_10299"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10299"/>
    <dbReference type="eggNOG" id="KOG2840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026481_5_1_1"/>
    <dbReference type="OrthoDB" id="198857at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24138">
        <property type="entry name" value="TtcA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686:SF1">
        <property type="entry name" value="AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686">
        <property type="entry name" value="SULFURTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="2">
        <location>
            <begin position="28"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="199" mass="22334" checksum="C1D058B34197BB46" modified="2007-05-15" version="1" fragment="single">FAKPSPKLLRMVNQAIQDFDMIQPGDRILLGLSGGKDSLAMLHILMCMMSRYPPGTFTLACATVDPGTEAFNPRPLIPYVESLGIEYHYLEEEIMAMADAHMTGDSICAFCARMKRGALYTCCRKYGYNKLVLAQHLDDCVESFLMSTMYNGTMRTMKASYLIDEGDITVIRPAIYLREKALRDFSYEAGLPVINENCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="109" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS90</accession>
    <name>A4RS90_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">plastoquinol--plastocyanin reductase</fullName>
            <ecNumber evidence="3">7.1.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PETC</name>
        <name evidence="19" type="ORF">OSTLU_40083</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>2 oxidized [plastocyanin] + a plastoquinol + 2 H(+)(in) = 2 reduced [plastocyanin] + a plastoquinone + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:22148"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="Rhea" id="RHEA-COMP:10039"/>
            <dbReference type="Rhea" id="RHEA-COMP:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="7.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.6" evidence="3"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416036.1">
        <property type="nucleotide sequence ID" value="XM_001415999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS90"/>
    <dbReference type="STRING" id="436017.A4RS90"/>
    <dbReference type="GeneID" id="4999411"/>
    <dbReference type="Gramene" id="ABO94328">
        <property type="protein sequence ID" value="ABO94328"/>
        <property type="gene ID" value="OSTLU_40083"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40083"/>
    <dbReference type="eggNOG" id="KOG1671">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_8_0_1"/>
    <dbReference type="OMA" id="FTPWTET"/>
    <dbReference type="OrthoDB" id="1637982at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009496">
        <property type="term" value="F:plastoquinol--plastocyanin reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010196">
        <property type="term" value="P:nonphotochemical quenching"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03471">
        <property type="entry name" value="Rieske_cytochrome_b6f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000007">
        <property type="entry name" value="Cytochrome b6-f complex iron-sulfur subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.700">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01335">
        <property type="entry name" value="Cytb6_f_Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023960">
        <property type="entry name" value="Cyt_b6_f_Rieske"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057415">
        <property type="entry name" value="TM_PetC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010001">
        <property type="entry name" value="PRK13474.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25471">
        <property type="entry name" value="TM_PetC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="18">
        <location>
            <begin position="101"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO94328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="216" mass="22927" checksum="FEB7B3AD152B83A4" modified="2007-05-15" version="1">MAFSLSTTQKLGCTRVRAQRAPVKRNAARSARTVVPRAASASADVPDMTKRSVMNLLLVGAIGLPATSLIGGYAYFFVPPSAGGGGAGQPAKDANGNDIKKGEWLKTHLPGDYSLTQGLKGDATYLIVKQDGSLTDFGLNAVCTHLGCVVPWNKAENKFKCPCHGSQYNADGKVIRGPAPLSLALAHVVVTDSDVVTFTPWTEADFRTGQNPPWWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSK6</accession>
    <name>A4RSK6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TrxG-related PHD-finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TrxG</name>
        <name evidence="8" type="ORF">OSTLU_119675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416227.1">
        <property type="nucleotide sequence ID" value="XM_001416190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSK6"/>
    <dbReference type="STRING" id="436017.A4RSK6"/>
    <dbReference type="GeneID" id="5000501"/>
    <dbReference type="Gramene" id="ABO94520">
        <property type="protein sequence ID" value="ABO94520"/>
        <property type="gene ID" value="OSTLU_119675"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119675"/>
    <dbReference type="eggNOG" id="KOG0825">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_391492_0_0_1"/>
    <dbReference type="OMA" id="YHTHCLV"/>
    <dbReference type="OrthoDB" id="498914at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15545">
        <property type="entry name" value="PHD_BAZ2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047157">
        <property type="entry name" value="PHRF1/Atg35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618:SF20">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="462"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="595"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="178"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="550"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="652"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="654"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="674"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="705" mass="76158" checksum="EB9EDFF26FD75B99" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT37</accession>
    <name>A4RT37_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Hel1</name>
        <name evidence="11" type="ORF">OSTLU_119483</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416141.1">
        <property type="nucleotide sequence ID" value="XM_001416104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT37"/>
    <dbReference type="STRING" id="436017.A4RT37"/>
    <dbReference type="GeneID" id="5000193"/>
    <dbReference type="Gramene" id="ABO94434">
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        <property type="gene ID" value="OSTLU_119483"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119483"/>
    <dbReference type="eggNOG" id="KOG0350">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="3370at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="59"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="301"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="446" mass="49859" checksum="D234CBC3FDB6D23B" modified="2007-05-15" version="1">MRAFVSGEKLRKRNGHDMNGECPRQITPVSPLDHRLYATLARGQLHSLLPVQKQTLSRALAGSFERDLCVTAPTGSGKTLSYLLPVLQILSKRVSKAETVCLILVPSGDLSAQVCVAASELCKALHVQISIVGKSRNTTNSTKLVNKRYRRLLAQNRQRMYQCCITRQFARHNSLDVPSQILVASPGRFAAHRTSILKKLKLLVIDEADRMLQQSYQNWLVTLDYEMCARTRQCRRLTVGERNSERLQLIFCSATLQSSCLQRVGAFALDRINAYDSVCPLLPITLSEYAIVAEHTDKFDALVSLLEFFKGEKVIVFSASVYRARHILQRLNKLENLPCFEYSSDANLRRRASTLQNFQRCQGGVLVASDAAARGLHIDAVSAVISFDAPEHFETYLHRAGRTARAGKTGKCITICSTAREAQTFIKRVQRHVPILLSTELQGSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT40</accession>
    <name>A4RT40_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416138.1">
        <property type="nucleotide sequence ID" value="XM_001416101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT40"/>
    <dbReference type="GeneID" id="5000365"/>
    <dbReference type="Gramene" id="ABO94431">
        <property type="protein sequence ID" value="ABO94431"/>
        <property type="gene ID" value="OSTLU_30006"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30006"/>
    <dbReference type="HOGENOM" id="CLU_3127597_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="50" mass="5735" checksum="D7CA599154577439" modified="2007-05-15" version="1">MSLPSSRPGFDSRMVHYSPSVVHDSPTLRGTDMLREVIYFSCTRDFENNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTA9</accession>
    <name>A4RTA9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416349.1">
        <property type="nucleotide sequence ID" value="XM_001416312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTA9"/>
    <dbReference type="GeneID" id="5000340"/>
    <dbReference type="Gramene" id="ABO94642">
        <property type="protein sequence ID" value="ABO94642"/>
        <property type="gene ID" value="OSTLU_29944"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29944"/>
    <dbReference type="HOGENOM" id="CLU_054664_0_0_1"/>
    <dbReference type="OMA" id="YMKKEHF"/>
    <dbReference type="OrthoDB" id="497253at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052734">
        <property type="entry name" value="Nod_factor_acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37312">
        <property type="entry name" value="MEMBRANE-BOUND ACYLTRANSFERASE YKRP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37312:SF1">
        <property type="entry name" value="MEMBRANE-BOUND ACYLTRANSFERASE YKRP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="38"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="46645" checksum="2BB2992EA27BB08D" modified="2007-05-15" version="1">MSRDARATRRARNLDASLDADAATPRAFDERASDRRDAYLDNLKYALMLIVVWNHALQEFLRALDAHERRGWCERDAVNATTHGHVRTLYLVLCATGMPLFAGASGYLSKSWLRAAREDEASAVNLLVRVRGAFGTLLGTYAVWQAFYVAINYYDVAPLQWWAPVGVMWYLLALFFWRMSVLVVGGLRNGVIVALSVFMGLFVGFTETATTKNGNAAFDWQRVFVYSVYFFLGCVALKPEHLQRLQSIDYGRRATFGAIVLAVAYALLYVVLNVFEECFDDVQWFIWSIAPYKSSSVAAQFIDMLKRIALYVFTAFAGLGVLALVPSKKSFITAMGSRTLYCYLTHILLVRGFSMLIDRVWPAAPLSFRLSAGALWLPLIVGNALMAQPVLFLKPVVEPDFSFLSRPRGAESVANVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="109" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTJ2</accession>
    <name>A4RTJ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyruvate, phosphate dikinase</fullName>
            <ecNumber evidence="3">2.7.9.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_29856</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>pyruvate + phosphate + ATP = phosphoenolpyruvate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10756"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416304.1">
        <property type="nucleotide sequence ID" value="XM_001416267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTJ2"/>
    <dbReference type="STRING" id="436017.A4RTJ2"/>
    <dbReference type="GeneID" id="5000530"/>
    <dbReference type="Gramene" id="ABO94597">
        <property type="protein sequence ID" value="ABO94597"/>
        <property type="gene ID" value="OSTLU_29856"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29856"/>
    <dbReference type="eggNOG" id="ENOG502QREJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015345_0_2_1"/>
    <dbReference type="OMA" id="HFFHEVG"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000038">
        <property type="entry name" value="Pyruvate, phosphate dikinase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.10">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.189.10">
        <property type="entry name" value="Pyruvate Phosphate Dikinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004531">
        <property type="entry name" value="PRK05878.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01828">
        <property type="entry name" value="pyru_phos_dikin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE DIKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931:SF9">
        <property type="entry name" value="PYRUVATE, PHOSPHATE DIKINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000853">
        <property type="entry name" value="PPDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="15">
        <location>
            <begin position="36"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="15">
        <location>
            <begin position="271"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme mobile" evidence="14">
        <location>
            <begin position="392"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme C-terminal" evidence="16">
        <location>
            <begin position="488"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="11">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="802"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="530"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="587"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="737"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="738"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="739"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="740"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="740"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO94597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="847" mass="91655" checksum="FF94037385631176" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTJ7</accession>
    <name>A4RTJ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">beta-ketoacyl-[acyl-carrier-protein] synthase I</fullName>
            <ecNumber evidence="2">2.3.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_29849</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001416263.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RTJ7"/>
    <dbReference type="GeneID" id="5000503"/>
    <dbReference type="Gramene" id="ABO94593">
        <property type="protein sequence ID" value="ABO94593"/>
        <property type="gene ID" value="OSTLU_29849"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29849"/>
    <dbReference type="eggNOG" id="KOG1394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_1"/>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF297">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="5">
        <location>
            <begin position="15"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="449" mass="46007" checksum="A727DFE38D334572" modified="2007-05-15" version="1">MSHYARGVPLDALYPRRVVVTGVGLVTPLARTTAENWRALLANAGATRALREDDLARECWNALAASDGARARTRHAGVVNRREGYDANAWSDGGSLASFVAYGRCAAKEAIEDAGMTSARDAPRDDVGVSFGAGMGGASDLTRAGGWMAKGELRRISPYFVPRILANAGAGRISMDHGFRGPNLAAATACATSAHCIGDAFRALQRGDANVMIAGGAEGCIDAVSLAAFAKARALSATGRAKPFDVARDGFVMGEGAGVLVLETLEHARARGVDKVYAEIRGYGASGDAHHVTRASPDGEGAARAMRAAMRDAGVDDPLDVGYVNAHATGTPLGDAAEAMALKTVFGADAIESGRVLTTSTKGATGHLLGAAGAIEAAYTVMALHTGDVPPTFGYDTVDPNLRIPIVGAGGVAARLRDDARAAMSNSFGFGGTNASLVFARAPPLDAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTM0</accession>
    <name>A4RTM0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane protein 184C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_3819</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416045.1">
        <property type="nucleotide sequence ID" value="XM_001416008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTM0"/>
    <dbReference type="STRING" id="436017.A4RTM0"/>
    <dbReference type="GeneID" id="5000364"/>
    <dbReference type="Gramene" id="ABO94337">
        <property type="protein sequence ID" value="ABO94337"/>
        <property type="gene ID" value="OSTLU_3819"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3819"/>
    <dbReference type="eggNOG" id="KOG2641">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012923_1_3_1"/>
    <dbReference type="OMA" id="QWRRWIR"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="38476" checksum="1D41017F98B613DF" modified="2007-05-15" version="1" fragment="single">VLLCALIVIALPFVSYDMKKHDYQTHYIAWFIAFVFVALSLPITLYEVTQHLENYRAPRLQRHVIRILFMVPIYAVNAWLALRFRSNTIIFDTVREFYEAYVIYNFYTYCIVYLQEFCSPGLSYIVARKATQPHIWPLNLFLRAPRMGEPFLRLCRHGVINYVVVRPVTSAAAFIADGNGVYGEGQILNPWVAYPYLVFINNLSQAWAMYCLILLYKVMYRELAPINPFWKFVSVKAVVFFSFWQSMAFAVLVKTGIISADDQAWASDYDAAELANGIQAFFICIEMFFAAIAHSYAFPPEEYNMGQAAAPQRKFSENIIELFDVRDVYQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTP6</accession>
    <name>A4RTP6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_49070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416824.1">
        <property type="nucleotide sequence ID" value="XM_001416787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTP6"/>
    <dbReference type="STRING" id="436017.A4RTP6"/>
    <dbReference type="GeneID" id="5000653"/>
    <dbReference type="Gramene" id="ABO95117">
        <property type="protein sequence ID" value="ABO95117"/>
        <property type="gene ID" value="OSTLU_49070"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49070"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OMA" id="YLPWSPL"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19094">
        <property type="entry name" value="AKR_Tas-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF17">
        <property type="entry name" value="ALDO KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="381" mass="42187" checksum="938ACBECBFD904B3" modified="2007-05-15" version="1">MAAVTSIPRTTLRRIPLGSAKDVFVTDVCLGTMTWGVQNTEAEAHEQLDYAVKQRGVNFIDTAEMYPVPSSDARWKPGTTEEIIGNWLAKNVELRKELVVATKVSGYQAKSETAGNRTVPAGAPCAARLDKQSIFQACDASLRRLRTDYIDLYQVHWPDRYLPIGAFTGSTEYIQSKERSDSVPIRETVEALGELIKAGKIRHYGLSNESTFGVCEFVRAADELGVPRPVSIQNSFCLLHRQFDTEVAEACSKSNYNILLLPWTPLAGGALSGKYLDGARPEGARMSVFKHFHQRYLNENSVKATKQYKEIADKAGMSLTTMALNWCKTRAFNTSTIIGATTLEQLKENIDAFEPSVVLSKETLKAIDAVHQQCRDPCIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUI5</accession>
    <name>A4RUI5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416676.1">
        <property type="nucleotide sequence ID" value="XM_001416639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUI5"/>
    <dbReference type="GeneID" id="5000682"/>
    <dbReference type="Gramene" id="ABO94969">
        <property type="protein sequence ID" value="ABO94969"/>
        <property type="gene ID" value="OSTLU_92450"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92450"/>
    <dbReference type="HOGENOM" id="CLU_1615128_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18444" checksum="C31D2C758C1B1BC1" modified="2007-05-15" version="1" fragment="single">VSFSVPSRVRSTIPVAPFTPSRDASSISIAARARRTISITFASNVRERRARARRDRPRGATCGMNARPTRVPHVPRPACAVGPRCRDRSRPNSIDASLDGRKSVHSIDRSIDRSIDLHTRLSIDGSGFNQSIDRSTRLSIDVDRCFVDASRFNRSIDLRVRRSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUR0</accession>
    <name>A4RUR0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_30708</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC124 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417003.1">
        <property type="nucleotide sequence ID" value="XM_001416966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUR0"/>
    <dbReference type="STRING" id="436017.A4RUR0"/>
    <dbReference type="GeneID" id="5001110"/>
    <dbReference type="Gramene" id="ABO95296">
        <property type="protein sequence ID" value="ABO95296"/>
        <property type="gene ID" value="OSTLU_30708"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30708"/>
    <dbReference type="eggNOG" id="KOG3223">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069723_0_0_1"/>
    <dbReference type="OMA" id="MANENHQ"/>
    <dbReference type="OrthoDB" id="76412at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coiled-coil" evidence="4">
        <location>
            <begin position="138"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="214" mass="23008" checksum="D0598057E34FA9EE" modified="2007-05-15" version="1">MPSTASVRRAQKNERETTKAIERSAAAKKAEEDAHWAAHGDGKKSKAAQRAEMDAAAADAKAAARAEARRQAAEEEAAFSGAKKAPAKKVTAYDLAQGKEMDAKARLKAKFAAKKAEQKIQESDEYDDAVLRANENRSIDVVSASGVDAALDALTVEERSASPAPLSGKAAYAAFEAEKLPELKAEKPGLRKQQYADLMSKLWARSPQNPQNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUU4</accession>
    <name>A4RUU4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416732.1">
        <property type="nucleotide sequence ID" value="XM_001416695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUU4"/>
    <dbReference type="GeneID" id="5000755"/>
    <dbReference type="Gramene" id="ABO95025">
        <property type="protein sequence ID" value="ABO95025"/>
        <property type="gene ID" value="OSTLU_92477"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92477"/>
    <dbReference type="eggNOG" id="ENOG502SFCW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021280_0_0_1"/>
    <dbReference type="OMA" id="ASCAPFM"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="638" mass="71602" checksum="0E027DA756E74A16" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVA8</accession>
    <name>A4RVA8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416809.1">
        <property type="nucleotide sequence ID" value="XM_001416772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVA8"/>
    <dbReference type="STRING" id="436017.A4RVA8"/>
    <dbReference type="GeneID" id="5001040"/>
    <dbReference type="Gramene" id="ABO95102">
        <property type="protein sequence ID" value="ABO95102"/>
        <property type="gene ID" value="OSTLU_30908"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30908"/>
    <dbReference type="eggNOG" id="KOG4288">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1070936_0_0_1"/>
    <dbReference type="OMA" id="SHMVKIN"/>
    <dbReference type="OrthoDB" id="497838at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF16">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="81"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="275" mass="28529" checksum="3C19ED803BFE6FC7" modified="2007-05-15" version="1">MKVTPSMLRRVVVFGGSGYVGSAIARALTLVTTSPAVKATTQTTSSDAAKADAKADASDAVDIVCASRTGAPPSWARDEPWAARARWVKCDALDVAQCRETVRGATAVVTAIGGLPFPWLKAEEIVRTNGATNVIPGRAAMEEGVRRLVVVGASIPPFVPGLASYAEGKAQVEAFARDEFASESNGRRAFILKPAAVSGTRRMGGGVTLPLSLVMDPTRAILRACGGALVENAPVPLENVARAAVKAALDDAYGNDGFTMITNKSLIEDFGGEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVD2</accession>
    <name>A4RVD2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YggT family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_10630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417118.1">
        <property type="nucleotide sequence ID" value="XM_001417081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVD2"/>
    <dbReference type="STRING" id="436017.A4RVD2"/>
    <dbReference type="GeneID" id="5001190"/>
    <dbReference type="Gramene" id="ABO95411">
        <property type="protein sequence ID" value="ABO95411"/>
        <property type="gene ID" value="OSTLU_10630"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10630"/>
    <dbReference type="HOGENOM" id="CLU_136788_4_0_1"/>
    <dbReference type="OMA" id="MYPLATI"/>
    <dbReference type="OrthoDB" id="2066at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010020">
        <property type="term" value="P:chloroplast fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219:SF14">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="YLMG HOMOLOG PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="CCB3_YggT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8360" checksum="B32AF25738810E4B" modified="2007-05-15" version="1" fragment="single">SAVESVITSGIFSTLNIYNTLIIGRLILTWFPNPPRQIMYPLATICDPYLNLFRGIIPPLGGIDLSPILAFTVLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVH7</accession>
    <name>A4RVH7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_19472</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Also involved in chromosome segregation in meiosis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Forms a heterodimer with SMC4. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: CAPH, CAPD2 and CAPG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417140.1">
        <property type="nucleotide sequence ID" value="XM_001417103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVH7"/>
    <dbReference type="STRING" id="436017.A4RVH7"/>
    <dbReference type="GeneID" id="5001188"/>
    <dbReference type="Gramene" id="ABO95433">
        <property type="protein sequence ID" value="ABO95433"/>
        <property type="gene ID" value="OSTLU_19472"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19472"/>
    <dbReference type="eggNOG" id="KOG0933">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_9_0_1"/>
    <dbReference type="OMA" id="THNKIAM"/>
    <dbReference type="OrthoDB" id="10255539at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000280">
        <property type="term" value="P:nuclear division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03273">
        <property type="entry name" value="ABC_SMC2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1060.20:FF:000005">
        <property type="entry name" value="Structural maintenance of chromosomes 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000278">
        <property type="entry name" value="Structural maintenance of chromosomes 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000385">
        <property type="entry name" value="Structural maintenance of chromosomes 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027120">
        <property type="entry name" value="Smc2_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="16">
        <location>
            <begin position="500"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1154"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="260"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="420"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="667"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="963"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1163"/>
            <end position="1173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00058390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00062012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO95433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1186" mass="130931" checksum="A4085722A3BADE18" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-10-05" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW69</accession>
    <name>LISC_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipoyl synthase, chloroplastic</fullName>
            <ecNumber evidence="1">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Lipoate synthase</fullName>
            <shortName evidence="1">LS</shortName>
            <shortName evidence="1">Lip-syn</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Lipoate synthase, plastidial</fullName>
            <shortName evidence="1">LIP1p</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Lipoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">LIP1P</name>
        <name type="ORF">OSTLU_31232</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H(+) = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Plastid</location>
            <location>Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">This protein may be expected to contain an N-terminal transit peptide but none has been predicted.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417274.1">
        <property type="nucleotide sequence ID" value="XM_001417237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW69"/>
    <dbReference type="SMR" id="A4RW69"/>
    <dbReference type="STRING" id="436017.A4RW69"/>
    <dbReference type="EnsemblPlants" id="ABO95567">
        <property type="protein sequence ID" value="ABO95567"/>
        <property type="gene ID" value="OSTLU_31232"/>
    </dbReference>
    <dbReference type="GeneID" id="5001263"/>
    <dbReference type="Gramene" id="ABO95567">
        <property type="protein sequence ID" value="ABO95567"/>
        <property type="gene ID" value="OSTLU_31232"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31232"/>
    <dbReference type="eggNOG" id="KOG2672">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033144_1_1_1"/>
    <dbReference type="OMA" id="RSCAFCQ"/>
    <dbReference type="OrthoDB" id="3231at2759"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000036">
        <property type="entry name" value="Lipoyl synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03129">
        <property type="entry name" value="Lipoyl_synth_plantC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027526">
        <property type="entry name" value="Lipoyl_synth_chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004019">
        <property type="entry name" value="PRK05481.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009544">
        <property type="entry name" value="PRK12928.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="LIPOYL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949:SF38">
        <property type="entry name" value="LIPOYL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01058">
        <property type="entry name" value="lipoyl_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0150">Chloroplast</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0934">Plastid</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000398866" description="Lipoyl synthase, chloroplastic">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="72"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="324" mass="35487" checksum="A494F5444E1D46E5" modified="2007-05-15" version="1">MCGPTATTVANAGTGGETIKGLPPGLKKPPWLRQRAPSGERFDYLSESLTGLKLNTVCEEAMCPNVGECWNGDTGTATVMLLGDTCTRGCRFCAVNTSQTPPPPDENEPENTAHAIAEWGVGYIVLTSVDRDDIPDGGSEHFARTVRTLKTIKSSVLVEALTPDFQGDMNAVAHLARSGLDVFAHNVETVERLQKRVRDPRANYEQSLAVLRHAKASKEGLVTKTSIMLGLGEEDEEIKQCMRACKEAGVDIFTLGQYLQPTPQHLPVKEFVTPEKFDFWKAYGEEVIGFRYVASGPLVRSSYKAGEFFIESMLRKDALDRGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWB0</accession>
    <name>A4RWB0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_37424</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the CDS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417296.1">
        <property type="nucleotide sequence ID" value="XM_001417259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWB0"/>
    <dbReference type="STRING" id="436017.A4RWB0"/>
    <dbReference type="GeneID" id="5001512"/>
    <dbReference type="Gramene" id="ABO95589">
        <property type="protein sequence ID" value="ABO95589"/>
        <property type="gene ID" value="OSTLU_37424"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37424"/>
    <dbReference type="eggNOG" id="KOG1440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037294_3_3_1"/>
    <dbReference type="OMA" id="CASTRTE"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47101:SF1">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47101">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="217"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO95589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="364" mass="39004" checksum="5A7431CF4DB96F56" modified="2007-05-15" version="1" fragment="single">SRPKPRPRDPRSRLPPPRRLARRSPSRRTWWGARVESAASDAAVGEGERKPTKGKGVSNLLKRTVSSLFMVAVGGVVIFAGGWPWALAMALFNGASCVEYFGMVREMNKELPYPPPEWCINLCVAACASLPVLLHATGGKMTSIIVATVISFTAICAALIVNEESHFNEFTSSLFGLIYCGFLPTFWVKLRGMSGVSLATPDSLLHHWPAWLGGPGIWTLGLAATITIVLSVVSADVGAYAFGKNFGKNKLTAVSPNKTVEGAIGGLLACAGTCAALFSVMGWPGTAWQGAFLGVTVFFTSVFGDLLESVMKRNATMKDSGNLIPGHGGLLDRFDSYIFTGSVTYFFVIAVLGGFRRVFSVGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWS1</accession>
    <name>A4RWS1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417380.1">
        <property type="nucleotide sequence ID" value="XM_001417343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWS1"/>
    <dbReference type="GeneID" id="5001579"/>
    <dbReference type="Gramene" id="ABO95673">
        <property type="protein sequence ID" value="ABO95673"/>
        <property type="gene ID" value="OSTLU_31437"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31437"/>
    <dbReference type="HOGENOM" id="CLU_1306650_0_0_1"/>
    <dbReference type="OMA" id="AWRVANL"/>
    <dbReference type="OrthoDB" id="498906at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="211" mass="23341" checksum="096A8848235A5FE4" modified="2007-05-15" version="1">MPTRLVSARTYESEPARGTPVSAIETRPRPQTIARAQGGVFAFVSPMFADMDDPQVRAVMEREFARELGLPEGELPVDLEHFMLARQLSRVVRLFALIDMVLCVLYALSGVSVIAVLLIGPLAGFVGARMYSPGLTACYVAFCVASIVWRILNFVFMKNVTARVLSVITIILATYITRLVIRFYHVVRVIPLEGQILLRQLDFANSAAPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWS2</accession>
    <name>A4RWS2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417627.1">
        <property type="nucleotide sequence ID" value="XM_001417590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWS2"/>
    <dbReference type="GeneID" id="5001646"/>
    <dbReference type="Gramene" id="ABO95920">
        <property type="protein sequence ID" value="ABO95920"/>
        <property type="gene ID" value="OSTLU_15226"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15226"/>
    <dbReference type="HOGENOM" id="CLU_843052_0_0_1"/>
    <dbReference type="OMA" id="MDTFCAH"/>
    <dbReference type="OrthoDB" id="10570705at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672000" description="Methyltransferase type 11 domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="36646" checksum="2B7F995A1E3CBB54" modified="2007-05-15" version="1">MALSRVVARPRRCRPTLFVLVAVACATLTWAHRAASKDANATTFVRPDGARVRAPPAPPSALASWFARGRAEDDDDETRAVTIGEAEMRATCGACEGMGAFVRAAAGRRRDARGLELACGTGTFLREMRERGFKIVGVDPRIARTRDRGGDLAAKGVATAASLRRLPYRRAFFDYVVAFETFGKMEMKATKENVDPVINEATRVAKKGAMMVFALAKTLDGGSPVGDEDETYQTRRWWMDTFCAHGWVEDREGYRKLITSEGSSSKRRVRRWFVLKRVKKVKKHGSCACFVPPGKDAESFCGGRGRPNARKEVKAFWKSLGRRRHQKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWW0</accession>
    <name>A4RWW0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31476</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417645.1">
        <property type="nucleotide sequence ID" value="XM_001417608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWW0"/>
    <dbReference type="STRING" id="436017.A4RWW0"/>
    <dbReference type="GeneID" id="5002058"/>
    <dbReference type="Gramene" id="ABO95938">
        <property type="protein sequence ID" value="ABO95938"/>
        <property type="gene ID" value="OSTLU_31476"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31476"/>
    <dbReference type="eggNOG" id="KOG1906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007219_0_0_1"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="403"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="781" mass="81562" checksum="341505D96A57706C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWY4</accession>
    <name>A4RWY4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GPN-loop GTPase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_12510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417902.1">
        <property type="nucleotide sequence ID" value="XM_001417865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWY4"/>
    <dbReference type="STRING" id="436017.A4RWY4"/>
    <dbReference type="GeneID" id="5001754"/>
    <dbReference type="Gramene" id="ABO96195">
        <property type="protein sequence ID" value="ABO96195"/>
        <property type="gene ID" value="OSTLU_12510"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12510"/>
    <dbReference type="eggNOG" id="KOG1534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037460_0_0_1"/>
    <dbReference type="OMA" id="KSTYCAN"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17872">
        <property type="entry name" value="GPN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030228">
        <property type="entry name" value="Gpn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF7">
        <property type="entry name" value="GPN-LOOP GTPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="276" mass="31367" checksum="E40CDD3C3D51BB7A" modified="2007-05-15" version="1">MPYAQLVVGPAGSGKSTYCYNIHQHCASIGRTVHVINLDPAADDFRYPVTADVRELISLEDVMEEEDLGPNGALMFCMEYFEDNMDDWLAEQLEGYTEDDMVIFDCPGQLELYSHHTAFRSFTKQMMNWGWRMVCVYVLDSQFITDGSKFIAGCLQAQSAMLHLELPHVNVFSKVDMLEDKTVLDPYLTPDHTALADELDERMDPKYRKLNRAIASVMEDFSLISFVPLDISDEDSLQFMLYQCDCAIGYGEDADVRTSRDVEHGDEPDMSNLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY40</accession>
    <name>A4RY40_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_9419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ycf54 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417865.1">
        <property type="nucleotide sequence ID" value="XM_001417828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY40"/>
    <dbReference type="STRING" id="436017.A4RY40"/>
    <dbReference type="GeneID" id="5002023"/>
    <dbReference type="Gramene" id="ABO96158">
        <property type="protein sequence ID" value="ABO96158"/>
        <property type="gene ID" value="OSTLU_9419"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9419"/>
    <dbReference type="eggNOG" id="ENOG502RY7F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2194210_0_0_1"/>
    <dbReference type="OMA" id="MQTYYYV"/>
    <dbReference type="OrthoDB" id="5200at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1860">
        <property type="entry name" value="Uncharacterised protein family Ycf54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019616">
        <property type="entry name" value="Ycf54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038409">
        <property type="entry name" value="Ycf54-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35319">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35319:SF2">
        <property type="entry name" value="YCF54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10674">
        <property type="entry name" value="Ycf54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00043978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="94" mass="11286" checksum="D24EB85992255292" modified="2007-05-15" version="1" fragment="single">QVKQFYYCVANADFMLNDENNEHFPEILRERRRFFKEKSKPQDFWIVPNPAFLDAMPDVKKKIRQPCVAVVTTDKVWNDFVKLRMDRVYKGGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="119" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYL8</accession>
    <name>A4RYL8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Plasma membrane ATPase</fullName>
            <ecNumber evidence="12">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_41354</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="12"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418414.1">
        <property type="nucleotide sequence ID" value="XM_001418377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYL8"/>
    <dbReference type="STRING" id="436017.A4RYL8"/>
    <dbReference type="GeneID" id="5002575"/>
    <dbReference type="Gramene" id="ABO96707">
        <property type="protein sequence ID" value="ABO96707"/>
        <property type="gene ID" value="OSTLU_41354"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41354"/>
    <dbReference type="eggNOG" id="KOG0205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_6_4_1"/>
    <dbReference type="OMA" id="TKHTIDC"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000042">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000005">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000008">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="624"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="658"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="693"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="774"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="803"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="13">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="864" mass="94312" checksum="A0777E7004A8AEB0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYX5</accession>
    <name>A4RYX5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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            <end position="20"/>
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            <end position="80"/>
        </location>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO96531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="294" mass="31135" checksum="58402DEDB2C670CD" modified="2007-05-15" version="1">MRRAGGATGDADALVDGARASGDDADAREAFVDALRRCATTLQVTALETAARAAREGGEKRASASERAREDAMDADETGERAVRAIERLASGLEDAASKSTTEVLDAATARATATLRELPENHARKVLDASSWTNAQRELIERVERALHDEYKARREMVAKRAQVTTTSFCYSARLNALKDVREEFARRVVSELHVAPQVTMDDVCDARYADLAVAGIKVTAGSDGLQSAVKKVLMGSVPDRGGRTDGSDRAAMPAFAARTDAPSGGRGGGGRGGGGDKPKPTPKPKKKGAVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZK0</accession>
    <name>A4RZK0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ABCG) family transporter: pleiotropic drug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_35308</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
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                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
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                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
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    </dbReference>
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        <property type="entry name" value="ABCG_dom"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
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            <end position="1101"/>
        </location>
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        <location>
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    </feature>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO96878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1268" mass="139520" checksum="AD233DD7B5C70C5E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZU8</accession>
    <name>A4RZU8_OSTLU</name>
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        <recommendedName>
            <fullName evidence="4">anthranilate synthase</fullName>
            <ecNumber evidence="4">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_87709</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterotetramer consisting of two non-identical subunits: a beta subunit and a large alpha subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anthranilate synthase component I family.</text>
    </comment>
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    <dbReference type="EMBL" id="CP000587">
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    </dbReference>
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    <dbReference type="Gramene" id="ABO96925">
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        <property type="gene ID" value="OSTLU_87709"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87709"/>
    <dbReference type="eggNOG" id="KOG1223">
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    <dbReference type="HOGENOM" id="CLU_006493_9_3_1"/>
    <dbReference type="OMA" id="GCVGYLD"/>
    <dbReference type="OrthoDB" id="1865897at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.120.10:FF:000003">
        <property type="entry name" value="Anthranilate synthase component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="10">
        <location>
            <begin position="30"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="9">
        <location>
            <begin position="244"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="526" mass="58301" checksum="61F86B5C1C1BC82A" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S013</accession>
    <name>A4S013_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_8500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418664.1">
        <property type="nucleotide sequence ID" value="XM_001418627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S013"/>
    <dbReference type="STRING" id="436017.A4S013"/>
    <dbReference type="GeneID" id="5002875"/>
    <dbReference type="Gramene" id="ABO96957">
        <property type="protein sequence ID" value="ABO96957"/>
        <property type="gene ID" value="OSTLU_8500"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8500"/>
    <dbReference type="eggNOG" id="KOG4400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1717994_0_0_1"/>
    <dbReference type="OMA" id="CQSERKP"/>
    <dbReference type="OrthoDB" id="3863715at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042246">
        <property type="entry name" value="ZCCHC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46242:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46242">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="153" mass="16063" checksum="17ED1508B0CB92D3" modified="2007-05-15" version="1" fragment="single">GGRGARGARGGRGGRGRGDARAPSSNGGIWRSKVTCFGCRGVGHTLRDCRVAKGGSATMRRGEKSCYNCGASDHAARDCAAAWTNYAHAKCFVCGETGHLSKSCPRNERGVYVNGGECKICKAKDHLVKDCPHKGDTCIRCGERGHFAAGCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S016</accession>
    <name>A4S016_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_35695</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418896.1">
        <property type="nucleotide sequence ID" value="XM_001418859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S016"/>
    <dbReference type="STRING" id="436017.A4S016"/>
    <dbReference type="GeneID" id="5002983"/>
    <dbReference type="Gramene" id="ABO97189">
        <property type="protein sequence ID" value="ABO97189"/>
        <property type="gene ID" value="OSTLU_35695"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35695"/>
    <dbReference type="eggNOG" id="ENOG502S7IP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061463_3_2_1"/>
    <dbReference type="OMA" id="HRQPFTK"/>
    <dbReference type="OrthoDB" id="5994at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_bL21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_bL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_bL21_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF7">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11657" checksum="D68DA121FE34FA36" modified="2007-05-15" version="1" fragment="single">AIIEVGGSQQFVSEGRFYECHSLKGVEPGSKIAFERVLGTHDGNAPNWGHPYVKGARVEATVLENFDAKKVIVFKYRPKKHYRKKNGHRQSMTRFLVTKVVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S023</accession>
    <name>A4S023_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418668.1">
        <property type="nucleotide sequence ID" value="XM_001418631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S023"/>
    <dbReference type="STRING" id="436017.A4S023"/>
    <dbReference type="GeneID" id="5002987"/>
    <dbReference type="Gramene" id="ABO96961">
        <property type="protein sequence ID" value="ABO96961"/>
        <property type="gene ID" value="OSTLU_32591"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32591"/>
    <dbReference type="eggNOG" id="KOG3937">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036039_1_0_1"/>
    <dbReference type="OMA" id="CAFSDII"/>
    <dbReference type="OrthoDB" id="201752at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13778">
        <property type="entry name" value="Aar2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13777">
        <property type="entry name" value="Aar2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.550">
        <property type="entry name" value="Aar2, C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007946">
        <property type="entry name" value="AAR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033648">
        <property type="entry name" value="AAR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038514">
        <property type="entry name" value="AAR2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033647">
        <property type="entry name" value="Aar2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038516">
        <property type="entry name" value="AAR2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689">
        <property type="entry name" value="A1 CISTRON SPLICING FACTOR AAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689:SF4">
        <property type="entry name" value="PROTEIN AAR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05282">
        <property type="entry name" value="AAR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20981">
        <property type="entry name" value="AAR2_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAR2 N-terminal" evidence="3">
        <location>
            <begin position="17"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="AAR2 C-terminal" evidence="2">
        <location>
            <begin position="184"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="434" mass="47440" checksum="57D6062DD8195DBC" modified="2007-05-15" version="1">MSSDARVAELDRRGYYVAVDVPRGATFALDTAEWTCDERFAGVKALTRGLHFVAVRDANERGAGERVGEFIDAAPGSVEIRRWDAAVETLGEGEGMSAEDAERARAATREGRAFDGGLAWYPTEVETRWMGLSGWITRDSLRRCGVDCGTRVVAGDPEAETRGDERGGVVPYFDNIQRAPTFTVNAVRKRPSGMTPAEVSAINIDANARLAHAVACFGDDGWRGLLGEFQLAFVLLMGLSSMAALEQWKHLAHVVCSCAETAVFDYPELYLGFVDALDAQLARAGEDFFVDDYTEDNFLRPCMVALMRIDVDDTPKREVTDMDVESTLDAISSKLAALARGVREKFDVDLIEEAREAKLADSSVVDAEEDAPVVVELSEGHYMAMNATDVDVESDAFKTDAESGAERMGWMRAYAPTSADHTPRNGSKFVNQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S025</accession>
    <name>A4S025_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418900.1">
        <property type="nucleotide sequence ID" value="XM_001418863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S025"/>
    <dbReference type="GeneID" id="5002640"/>
    <dbReference type="Gramene" id="ABO97193">
        <property type="protein sequence ID" value="ABO97193"/>
        <property type="gene ID" value="OSTLU_32593"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32593"/>
    <dbReference type="HOGENOM" id="CLU_793190_0_0_1"/>
    <dbReference type="OrthoDB" id="435273at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="254"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="350" mass="37895" checksum="C05309C902E76614" modified="2007-05-15" version="1">MFAWTYDLPLGAYAFGGTVREASEQRTQKIAVIVIGYVLEIFLVLGYARAGKKRMHPKFRLNRRRARRLLVHVAFGTMELTLGARALLVGGGARGTMRASAACVLVIALTAMLQIDASFGTPSIITPALHIINTAHIEKAFRVLIGAGALSSDSSGAVLENFIDQLVLAQGFVYSRMFIFAFTNVPGIKEHRYTTGATLALFLVIPAVYGPVGALIAIVIIAAYSNACGSEESGKERNFAAICGRVNSLVRLRIGKTPLRTAFDVLDKDGNGTLDGSELREQLFTWGVDARDIKELFERIDISNRGSLSFEEILNDTAGQAMLEYISVLLHDNESLDGAPHSSSRASKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0H2</accession>
    <name>A4S0H2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418971.1">
        <property type="nucleotide sequence ID" value="XM_001418934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0H2"/>
    <dbReference type="GeneID" id="5002771"/>
    <dbReference type="Gramene" id="ABO97264">
        <property type="protein sequence ID" value="ABO97264"/>
        <property type="gene ID" value="OSTLU_93054"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93054"/>
    <dbReference type="HOGENOM" id="CLU_1505446_0_0_1"/>
    <dbReference type="OMA" id="DQGEQRW"/>
    <dbReference type="OrthoDB" id="497930at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="20012" checksum="4C02E44DC23FDD97" modified="2007-05-15" version="1">MASARCANARELACGRASSNRVASRGRRAVCAPRRAVESSGLSEIVTLDSGIKAGFIVFGARVAALGLGKAKQGSDVDRALEDCAARGIDVSDLYYAEDQGEQRWYLVGNWKVPRAGDAKYGDGRMSQELKSRVRYHDAKAVADEAGVSYVDIDEHTALYPTTPKRALELRRRLTAAGFETKWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0M0</accession>
    <name>A4S0M0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SNF2 family DNA-dependent ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CHR3508</name>
        <name evidence="6" type="ORF">OSTLU_16250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
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                <person name="Podell S."/>
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                <person name="Tai V."/>
                <person name="Vallon O."/>
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</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Salamov A."/>
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                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
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                <person name="Zhou K."/>
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                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
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        </source>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="117" xmlns="https://uniprot.org/uniprot">
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        </lineage>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
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                <person name="Dupont C."/>
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                <person name="Zhou K."/>
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                <person name="Schmutz J."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H2B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419128.1">
        <property type="nucleotide sequence ID" value="XM_001419091.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420602.1">
        <property type="nucleotide sequence ID" value="XM_001420565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1C9"/>
    <dbReference type="STRING" id="436017.A4S1C9"/>
    <dbReference type="GeneID" id="5003089"/>
    <dbReference type="GeneID" id="5004636"/>
    <dbReference type="Gramene" id="ABO97421">
        <property type="protein sequence ID" value="ABO97421"/>
        <property type="gene ID" value="OSTLU_12804"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO98895">
        <property type="protein sequence ID" value="ABO98895"/>
        <property type="gene ID" value="OSTLU_13105"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12804"/>
    <dbReference type="KEGG" id="olu:OSTLU_13105"/>
    <dbReference type="eggNOG" id="KOG1744">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075666_2_1_1"/>
    <dbReference type="OMA" id="ELAKHAX"/>
    <dbReference type="OrthoDB" id="2018474at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000014">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="13"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="112" mass="12325" checksum="78B500757CC92A65" modified="2007-05-15" version="1">MAKKPAQKKPSGAKKVGRKSKSETYKIYIYKVLKQVHPDTGISSKAMSIMNSFINDIFEKIATEAAKLARYNKKPTVTSREIQTAVRLILPGELAKHAVSEGTKAVTKFTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1D5</accession>
    <name>A4S1D5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PRPL31</name>
        <name evidence="4" type="ORF">OSTLU_33061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bL31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419346.1">
        <property type="nucleotide sequence ID" value="XM_001419309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1D5"/>
    <dbReference type="GeneID" id="5003092"/>
    <dbReference type="Gramene" id="ABO97639">
        <property type="protein sequence ID" value="ABO97639"/>
        <property type="gene ID" value="OSTLU_33061"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33061"/>
    <dbReference type="HOGENOM" id="CLU_2612958_0_0_1"/>
    <dbReference type="OMA" id="MPRKGIH"/>
    <dbReference type="OrthoDB" id="1840965at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="entry name" value="Ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_bL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_bL31_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="81" mass="8888" checksum="E955E1A97CAFCF98" modified="2007-05-15" version="1">MPRKGIHPLLHRLTVVATNGSTRRVPTTVKQLGDYLFLTLDANNHPAYTGKVIKGPATGQAAKFKRKFDFLTNATLGKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1E0</accession>
    <name>A4S1E0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419133.1">
        <property type="nucleotide sequence ID" value="XM_001419096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1E0"/>
    <dbReference type="GeneID" id="5003095"/>
    <dbReference type="Gramene" id="ABO97426">
        <property type="protein sequence ID" value="ABO97426"/>
        <property type="gene ID" value="OSTLU_16449"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16449"/>
    <dbReference type="HOGENOM" id="CLU_1680845_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="157" mass="17122" checksum="4569A32C59F2B7B7" modified="2007-05-15" version="1">MMAREASASVSDDDARAGRRANASTSSESESESETSPRARAVVDDGCLDSDDFETSLKALEPRRRNIDATIRAQERACVDITLAVDAMRAFLTNARDDEESSEGAEERRDALEAAALTKRIVAIAMETRAIVNRVRQKLIEAGFVDVEALTPYDPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1F5</accession>
    <name>A4S1F5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_93136</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <location>
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        </location>
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        <location>
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        <location>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="348" mass="39085" checksum="B47B36878E4AFDE6" modified="2007-05-15" version="1">MATTTAWATAEDTARKDLDDAAKRCDDDAHRWRKYGHKKIGKRDKTSNDLSERSYYRCSFEGCPARKRVGWCPETGHTRVWYEFEHTCGQVMRGPCSQCGTKESPQWRRGTCAKPVLCNACGVRYRKTQAVRDETDEMNAQGPVKKRPMVTDPANNDVGEKRANVVTSNGQVARIKRGRSKKSVPKELLSAAKRVVELSRAPEGNSLFQHVLIPRAPRTSATVATKPLIPAPKPLTVPEGVRNIRLFARVQTENGNKTVLKPVRVMVSSQVEVEKLRTQLTIRDASLKAERARAQALEAKVNFLRAQLECKALRARLRETAVSKAPEERPRSSPSMNEQAREKLEVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Heijde M."/>
                <person name="Jabbari K."/>
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                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
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                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
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            <location evidence="1">Cilium axoneme</location>
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    </comment>
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            <end position="936"/>
        </location>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
    <sequence length="936" mass="100281" checksum="F0AC80DDC75425CF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
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                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
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                <person name="Napoli C."/>
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                <person name="Manuell A."/>
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                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419188.1">
        <property type="nucleotide sequence ID" value="XM_001419151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Q3"/>
    <dbReference type="GeneID" id="5003188"/>
    <dbReference type="Gramene" id="ABO97481">
        <property type="protein sequence ID" value="ABO97481"/>
        <property type="gene ID" value="OSTLU_93155"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93155"/>
    <dbReference type="HOGENOM" id="CLU_2475557_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="88" mass="10141" checksum="59D7A8D386C45B2B" modified="2007-05-15" version="1" fragment="single">VSAGTDPAKNWILRGMPRIERGASPKFKQALFSAGYYPKGESIDQRTRAYSQYIGLFKVWVCARSRRRERLTIPLDHIPFTRCLIARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S291</accession>
    <name>A4S291_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419707.1">
        <property type="nucleotide sequence ID" value="XM_001419670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S291"/>
    <dbReference type="GeneID" id="5003916"/>
    <dbReference type="Gramene" id="ABO98000">
        <property type="protein sequence ID" value="ABO98000"/>
        <property type="gene ID" value="OSTLU_33368"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33368"/>
    <dbReference type="HOGENOM" id="CLU_892524_0_0_1"/>
    <dbReference type="OMA" id="VGVNRRD"/>
    <dbReference type="OrthoDB" id="497993at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="33625" checksum="5C0C1F3CFC211FA3" modified="2007-05-15" version="1">MIRVASSSASSARVCVVGARSLTGRLIAGMLARRGGDGVALVVEDADSYVPRDMPEDVFERRFGTSAAAMMKCALVNENDDEAVERAMRASDVVIVAHESGARSEAAAASVRRGATKAKRVVALSRVGVNRRDENPFKEQNRPVQKMVKVGQMNLPIGGDVDGSKGLLDSYAAAEATLERGAKELGYALTVVRSGQLRGNGPLLLGDYSARLVDNMYDVKFQDLYLKRGDTSEGYTKRLNLAQFIAHVSTTRVDDAPDDVEVLSVVTKTNFFGEQSLTPPTDRERRKGYDMAKGKAPAAIDVEIIDALLAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Q2</accession>
    <name>A4S2Q2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419572.1">
        <property type="nucleotide sequence ID" value="XM_001419535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Q2"/>
    <dbReference type="GeneID" id="5003778"/>
    <dbReference type="Gramene" id="ABO97865">
        <property type="protein sequence ID" value="ABO97865"/>
        <property type="gene ID" value="OSTLU_16797"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16797"/>
    <dbReference type="HOGENOM" id="CLU_1191585_0_0_1"/>
    <dbReference type="OrthoDB" id="10590846at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="233" mass="26640" checksum="B44E39CF771F3CBC" modified="2007-05-15" version="1">MPPKKVLGEKRLTAEEKKRKEEKEKREKDKERKERKAQLAADRTFGLKNKNVSAKVAAKVDDLKRDAPTKEAERARAEARAREKKKQKDAEEAAKRELEILMGVRSAIPERRKVAAEGEDALAGELESMVVTAEPKNFVRKTVETQNEATEPTKELTEEERREIIAKIELEKARVKEAELKAKVDVNPFHVDDEGWYDSDEDPFELLKMVAGNKRAIIMPKGYEDPDEDAMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2U8</accession>
    <name>A4S2U8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP-dependent DNA helicase RecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_34911</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419597.1">
        <property type="nucleotide sequence ID" value="XM_001419560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2U8"/>
    <dbReference type="STRING" id="436017.A4S2U8"/>
    <dbReference type="GeneID" id="5003812"/>
    <dbReference type="Gramene" id="ABO97890">
        <property type="protein sequence ID" value="ABO97890"/>
        <property type="gene ID" value="OSTLU_34911"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34911"/>
    <dbReference type="eggNOG" id="KOG0344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005122_7_1_1"/>
    <dbReference type="OMA" id="IATHAIW"/>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17992">
        <property type="entry name" value="DEXHc_RecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047112">
        <property type="entry name" value="RecG/Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47964">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47964:SF1">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_dom3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="103"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="286"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="57527" checksum="DC83BCFF32410DE5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S338</accession>
    <name>A4S338_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DMT family transporter: phosphate/phosphoenolpyruvate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_34640</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419646.1">
        <property type="nucleotide sequence ID" value="XM_001419609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S338"/>
    <dbReference type="GeneID" id="5003856"/>
    <dbReference type="Gramene" id="ABO97939">
        <property type="protein sequence ID" value="ABO97939"/>
        <property type="gene ID" value="OSTLU_34640"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34640"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022332_3_0_1"/>
    <dbReference type="OMA" id="NAMCAFA"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="34"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="350" mass="37375" checksum="70C1225E588C1A92" modified="2007-05-15" version="1">MPASSDAPSTTPATRDADARSRRVVAKALADNALVALWVGTSAIVILFNKYILTAYGFPFPVALTMTHMLFCSVVAFVIVRALKLVPASEGVTREVYATKITPIAALFAVSLWASNTAYVYLSVAFIQMLKALSPVVVYAIGCSIGVERYSHERLANMAVVTLGVMIASYGELNFNFFGFAVQLVAVLAESCRIIAVQLVLGKANLKLNSITTLYYVSPACFVFLIVPFAMLELPRLAYGLEVTHSVRYSAGIMLANAMCAFALNAVIYLLIGRTSALTLNVAGVVKDMFLIGISSVIFEAPISATQLVGSLIAFGGVCYYNYRKLNDAFAAAAAAPTQGEVGPKRDSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3A0</accession>
    <name>A4S3A0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_38084</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419882.1">
        <property type="nucleotide sequence ID" value="XM_001419845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3A0"/>
    <dbReference type="STRING" id="436017.A4S3A0"/>
    <dbReference type="GeneID" id="5004119"/>
    <dbReference type="Gramene" id="ABO98175">
        <property type="protein sequence ID" value="ABO98175"/>
        <property type="gene ID" value="OSTLU_38084"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38084"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="KKTHDMY"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="16">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="58"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="266"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO98175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="440" mass="47887" checksum="9FA3F2A7BA4CF8F3" modified="2007-05-15" version="1">MSASEVQAARDALAVTQVDGLSTDLAPVSSFADAGFSKELLRVTAQFKTPSPIQAQSWPIIMSGHDMVGIAATGSGKTLAFGMPALTQIHSQPPCKPGQPICLVLAPTRELAQQTAKVFDDAGEASGVRCVCVYGGAPKYEQKAQMKAGGGAAVIVATPGRLRDFMEEGVIKLDRVTMLVLDEADRMLDLGFEPEIRAIAGATRADRQTVMFSATWPQSVQSLASEFMCNPIKVRIGAEGLKASQSITQIVEVVEPQDKDRHLARVMKQYLGKGKEVPRTLIFGLYKKECANLHQRLSREWPAVCIHGDMSQHDREKSVDAFKKGTSRILIATDVAARGLDIKEVEYVINYTFPLTTEDYVHRIGRTGRAGATGLAHTFFTLHDKARAGELVNVLRKAGAEVPEELTKFGTHVKKKESKLYGAHFKDVDMSVKATKITFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3L4</accession>
    <name>A4S3L4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419940.1">
        <property type="nucleotide sequence ID" value="XM_001419903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3L4"/>
    <dbReference type="GeneID" id="5004272"/>
    <dbReference type="Gramene" id="ABO98233">
        <property type="protein sequence ID" value="ABO98233"/>
        <property type="gene ID" value="OSTLU_17039"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17039"/>
    <dbReference type="HOGENOM" id="CLU_1470522_0_0_1"/>
    <dbReference type="OMA" id="IANWVFL"/>
    <dbReference type="OrthoDB" id="10555310at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="19201" checksum="54730DF4956BAB6C" modified="2007-05-15" version="1">MSLVVARASTRAPTRAGASARPSHPSRSRFPARGLSPVCRSSASGDGVPDPISAREKADAARKALQGALGNKRDVLSKFDGGGKGGGPLDWFFGGGGGDDDGENAQARKIANWVFLAFVVLLLFKPVTAVIVNAVYYAFGWRTGREAPTEAELAAMNAPADASVISKYAADDDDDDDDDDDDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3U7</accession>
    <name>A4S3U7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4-aminobutyrate--2-oxoglutarate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GABA aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Gamma-amino-N-butyrate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_38108</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23352"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="2.6.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.19" evidence="3"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419983.1">
        <property type="nucleotide sequence ID" value="XM_001419946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3U7"/>
    <dbReference type="STRING" id="436017.A4S3U7"/>
    <dbReference type="GeneID" id="5004164"/>
    <dbReference type="Gramene" id="ABO98276">
        <property type="protein sequence ID" value="ABO98276"/>
        <property type="gene ID" value="OSTLU_38108"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38108"/>
    <dbReference type="eggNOG" id="KOG1405">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_12_0_1"/>
    <dbReference type="OMA" id="GLMCAFD"/>
    <dbReference type="OrthoDB" id="496381at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034386">
        <property type="term" value="F:4-aminobutyrate:2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000073">
        <property type="entry name" value="Probable 4-aminobutyrate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004631">
        <property type="entry name" value="4NH2But_aminotransferase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00699">
        <property type="entry name" value="GABAtrns_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206:SF1">
        <property type="entry name" value="4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="17"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="500" mass="54361" checksum="80B2870D8E01D4B0" modified="2007-05-15" version="1">MLARALERCARRRAREAISRASRDARASTRASSSSSRAGTSNGEPAAPVVRTPIPGPASRRAVEALSAHADVGSIRYFVDVDASRGNYVVDADGNAVLDLYAHIASLPVGYNHEKMLAAMRDEANVGILAHRPALGNNPPIGWDDRVARTLMRVAPKGLTRATTMACGACANEHAMKAVFISAANARRGGREISEEEKVSCLTNQAPGSPGFKVLSFDGAFHGRTAACLSLTHTKWIHKLDFPTFDWPSCPFPKLKYPLDKFERENAEEEARCLAEVEKALTRDRDVVAVIVEPMQAEGGDNHASADFFRKLRALTKRENVRMIVDEVQTGCGSSGTFWAHEAWGLEHPPDIVTFSKKMQIAGFYAAADLAPELPYRIFNTWMGDPAKLIQLEVVLDCIEEHHLLDVVKSAGETLLNGLRELQEKYPSILANARGVGTLVAIDCDTSARRDALLHALLQKGVDIGGCGSATIRARPGLLFTSAHAGVFLERFERVLAAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4B0</accession>
    <name>A4S4B0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420400.1">
        <property type="nucleotide sequence ID" value="XM_001420363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4B0"/>
    <dbReference type="GeneID" id="5004278"/>
    <dbReference type="Gramene" id="ABO98693">
        <property type="protein sequence ID" value="ABO98693"/>
        <property type="gene ID" value="OSTLU_93405"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93405"/>
    <dbReference type="HOGENOM" id="CLU_1144166_0_0_1"/>
    <dbReference type="OMA" id="ANFTRAP"/>
    <dbReference type="OrthoDB" id="10532771at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="243" mass="26300" checksum="AA14A629288018E1" modified="2007-05-15" version="1">MRANFTRAPSRGPSTSTSGAASRAARARSAGDGECAFTDANDRAVEKFWRNWTGAAHCRQIVTKSSRESLYRDPARLESKVRALLRVFPVDGDGNCGSHGLDVPASAAREPRLLALREDEFVKRVLMVKRCVAGISGRQITLAPGLLLCDGRALEEAMRGLEETLGAAEARDAVAKQPDRLLELVGFYGVGDDAEEEERDIGRAMRHYARAVPPVSDARAVEQRVAARELGAKKFHVGESGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4J7</accession>
    <name>A4S4J7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH HARE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26433</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420277.1">
        <property type="nucleotide sequence ID" value="XM_001420240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4J7"/>
    <dbReference type="STRING" id="436017.A4S4J7"/>
    <dbReference type="GeneID" id="5004345"/>
    <dbReference type="Gramene" id="ABO98570">
        <property type="protein sequence ID" value="ABO98570"/>
        <property type="gene ID" value="OSTLU_26433"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26433"/>
    <dbReference type="HOGENOM" id="CLU_074692_0_0_1"/>
    <dbReference type="OMA" id="EPQHWER"/>
    <dbReference type="OrthoDB" id="515923at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007759">
        <property type="entry name" value="Asxl_HARE-HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044977">
        <property type="entry name" value="RLT1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36968">
        <property type="entry name" value="HOMEOBOX-DDT DOMAIN PROTEIN RLT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36968:SF5">
        <property type="entry name" value="HOMEOBOX-DDT DOMAIN PROTEIN RLT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05066">
        <property type="entry name" value="HARE-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51913">
        <property type="entry name" value="HTH_HARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HTH HARE-type" evidence="3">
        <location>
            <begin position="118"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="323" mass="35925" checksum="45E08552938C2A1C" modified="2007-05-15" version="1">MARSVGSGAMPASAEDSIGWYLSLYWPAMNKEFKGVVQKYDHDSKHHTVKWDNAPKGSDGVTEVDLTEGELTWLKAPEKPVKKAAKGKPAAAKAKPKAYKEYDALETMDDLEARFTGKTTKAVAFQVLKNSGVNGMTLQEIVDESQKLGLRDWTQCKQPKTTINVCVSQDSAFVKISPGRVGLRINGAQTRDASQEPKHVKASGASKKRGRPPKTGEAKPKKVQRQEPQHWERKPPIDLSIEVYTSNNTHVTNAPISVAYNVTIKALKKAISNNTKGMLKPHYQQLYHDNRNIGMDEDAFLVHAVRPHKFERTLDLKLVISDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4K5</accession>
    <name>A4S4K5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquinone biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_26441</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the COQ9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420281.1">
        <property type="nucleotide sequence ID" value="XM_001420244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4K5"/>
    <dbReference type="STRING" id="436017.A4S4K5"/>
    <dbReference type="GeneID" id="5004578"/>
    <dbReference type="Gramene" id="ABO98574">
        <property type="protein sequence ID" value="ABO98574"/>
        <property type="gene ID" value="OSTLU_26441"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26441"/>
    <dbReference type="eggNOG" id="KOG2969">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1167533_0_0_1"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.10">
        <property type="entry name" value="Tetracycline Repressor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012762">
        <property type="entry name" value="Ubiq_biosynth_COQ9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02396">
        <property type="entry name" value="diverge_rpsU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="COQ9 C-terminal" evidence="9">
        <location>
            <begin position="90"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="26057" checksum="27D11102701D8219" modified="2007-05-15" version="1">MRAIVRGDAGAGARDSGPGDGLAGELAGYFEECADAAFHAKVVAEGETLRAMKSRERVKWLMRARLEMIESKLDSWPRALAAMATPRYAMTTLRRRAALADFIADAADVDALDVLPDSLDTFRWHAERAAMLALYAATELRLLTDSSKDRRKTWAFLDARVDDIARSRVDVLELKSYIDVFARDADLTTLGASFASKDALAAAFAPVADVFARASRAVFSTPSRDASERDPPRDSPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4X4</accession>
    <name>A4S4X4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAM192A/Fyv6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_26562</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420344.1">
        <property type="nucleotide sequence ID" value="XM_001420307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4X4"/>
    <dbReference type="STRING" id="436017.A4S4X4"/>
    <dbReference type="GeneID" id="5004397"/>
    <dbReference type="Gramene" id="ABO98637">
        <property type="protein sequence ID" value="ABO98637"/>
        <property type="gene ID" value="OSTLU_26562"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26562"/>
    <dbReference type="HOGENOM" id="CLU_1236505_0_0_1"/>
    <dbReference type="OMA" id="GWKTMKQ"/>
    <dbReference type="OrthoDB" id="75807at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039845">
        <property type="entry name" value="FAM192A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019331">
        <property type="entry name" value="FAM192A/Fyv6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495">
        <property type="entry name" value="NEFA-INTERACTING NUCLEAR PROTEIN NIP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495:SF0">
        <property type="entry name" value="PSME3-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10187">
        <property type="entry name" value="FAM192A_Fyv6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM192A/Fyv6 N-terminal" evidence="4">
        <location>
            <begin position="58"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="130"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="25677" checksum="C03AF88D4627212B" modified="2007-05-15" version="1">MAPGVEMVRVERAERAYDREKALGRDAASVFPSLARDGDGAADGDARKDDDDATRKKFVTESELERLRALGGSDGGDASGASDARNDDANAGKPLYQILAERREEKDREFQEQWASMKVGKNKPLDEEEVEFLDEIESERRAAETKRKREEDGELEAFKRAQRGDDQGGMTTTKGDGETATTSAPAAVVARKRPSAGVRAKPKTAIASETKETDDASEGLGGLLGDYGSDSDDDIADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S510</accession>
    <name>A4S510_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ferrochelatase</fullName>
            <ecNumber evidence="9">4.98.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_2831</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>heme b + 2 H(+) = protoporphyrin IX + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.98.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Plastid</location>
            <location evidence="1 9">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="4.98.1.1" evidence="9"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420361.1">
        <property type="nucleotide sequence ID" value="XM_001420324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S510"/>
    <dbReference type="STRING" id="436017.A4S510"/>
    <dbReference type="GeneID" id="5004416"/>
    <dbReference type="Gramene" id="ABO98654">
        <property type="protein sequence ID" value="ABO98654"/>
        <property type="gene ID" value="OSTLU_2831"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2831"/>
    <dbReference type="eggNOG" id="KOG1321">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018884_4_1_1"/>
    <dbReference type="OMA" id="RFLSGYC"/>
    <dbReference type="OrthoDB" id="1323at2759"/>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1400:FF:000006">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108:SF1">
        <property type="entry name" value="FERROCHELATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="7 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="366" mass="40571" checksum="73EA7FDEC43808B2" modified="2007-05-15" version="1" fragment="single">KVGVLLLNLGGPETLDDVQPFLYNLFADPDIIRLPPPVQFLQGFLANTLSASRAPKSREAYESIGGGSPLRRITEDQANALQAAMQARGIQAKTYVGMRYWKPFTEDAIDAIKRDGVTRLVVLPLYPQFSISTSGSSLRLLEQYFAEDEELASVRHTVIPSWYQRPGYVKAMAVMIAQTLKTKFEDDKEPLIFFSAHGVPVSYVEQAGDPYKDEMEACVRLITEELGSMGVNNEHVLAYQSRVGPVEWLKPYTDDTIRELGKKGTEALCAVPISFVSEHIETLEEIDMEYRELAEESGIKKWGRVPALDTDPLFIDDLADAVIEALPYTTRMSKTRASASGLNVPPAEVGELLASYDRAKLAIPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5B8</accession>
    <name>A4S5B8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative psbM, PSII-M, photosystem II polypeptide, typically encoded in the chloroplast genome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">psbM</name>
        <name evidence="10" type="ORF">OSTLU_26707</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420746.1">
        <property type="nucleotide sequence ID" value="XM_001420709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5B8"/>
    <dbReference type="STRING" id="436017.A4S5B8"/>
    <dbReference type="GeneID" id="5004845"/>
    <dbReference type="Gramene" id="ABO99039">
        <property type="protein sequence ID" value="ABO99039"/>
        <property type="gene ID" value="OSTLU_26707"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26707"/>
    <dbReference type="HOGENOM" id="CLU_1819097_0_0_1"/>
    <dbReference type="OrthoDB" id="564131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00438">
        <property type="entry name" value="PSII_PsbM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007826">
        <property type="entry name" value="PSII_PsbM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037269">
        <property type="entry name" value="PSII_PsbM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03038">
        <property type="entry name" value="PS_II_psbM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35774">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER PROTEIN M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35774:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER PROTEIN M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05151">
        <property type="entry name" value="PsbM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161033">
        <property type="entry name" value="Photosystem II reaction center protein M, PsbM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="2" id="KW-0674">Reaction center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="142" mass="14741" checksum="C09AD2BFD555CDC4" modified="2007-05-15" version="1">MAVLALNTGLIPLAARAATRRTATKRVVAPKAATTTKAQQKVRTTAVAATPAAIAAPAFAASEALEQVALADVNILGVIATALFIIIPTAFLIVLYVKSSSEGNVSGGFSQEYYDKSKKRGDKKTNEAAVLKGKGLGMRPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5P8</accession>
    <name>A4S5P8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-ketoglutarate-dependent dioxygenase FTO</fullName>
            <ecNumber evidence="5">1.14.11.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">mRNA N(6)-methyladenosine demethylase FTO</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">tRNA N1-methyl adenine demethylase FTO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">OSTLU_17601</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>N(6)-methyladenosine in U6 snRNA + 2-oxoglutarate + O2 = adenosine in U6 snRNA + formaldehyde + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:57900"/>
            <dbReference type="Rhea" id="RHEA-COMP:13573"/>
            <dbReference type="Rhea" id="RHEA-COMP:13574"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in U6 snRNA + 2-oxoglutarate + O2 = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in U6 snRNA + formaldehyde + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:57904"/>
            <dbReference type="Rhea" id="RHEA-COMP:15030"/>
            <dbReference type="Rhea" id="RHEA-COMP:15031"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:85958"/>
            <dbReference type="ChEBI" id="CHEBI:85959"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in mRNA + 2-oxoglutarate + O2 = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in mRNA + formaldehyde + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:57896"/>
            <dbReference type="Rhea" id="RHEA-COMP:11518"/>
            <dbReference type="Rhea" id="RHEA-COMP:11519"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:85958"/>
            <dbReference type="ChEBI" id="CHEBI:85959"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>an N(1)-methyladenosine in tRNA + 2-oxoglutarate + O2 = an adenosine in tRNA + formaldehyde + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54576"/>
            <dbReference type="Rhea" id="RHEA-COMP:10242"/>
            <dbReference type="Rhea" id="RHEA-COMP:12312"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74491"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>an N(6)-methyladenosine in mRNA + 2-oxoglutarate + O2 = an adenosine in mRNA + formaldehyde + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:49520"/>
            <dbReference type="Rhea" id="RHEA-COMP:12414"/>
            <dbReference type="Rhea" id="RHEA-COMP:12417"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="1.14.11.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Monomer. May also exist as homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alkB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fto family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.53" evidence="5"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420808.1">
        <property type="nucleotide sequence ID" value="XM_001420771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5P8"/>
    <dbReference type="STRING" id="436017.A4S5P8"/>
    <dbReference type="GeneID" id="5004766"/>
    <dbReference type="Gramene" id="ABO99101">
        <property type="protein sequence ID" value="ABO99101"/>
        <property type="gene ID" value="OSTLU_17601"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17601"/>
    <dbReference type="eggNOG" id="ENOG502QR31">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041676_0_0_1"/>
    <dbReference type="OMA" id="NYSCEGS"/>
    <dbReference type="OrthoDB" id="46257at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990931">
        <property type="term" value="F:mRNA N6-methyladenosine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040014">
        <property type="term" value="P:regulation of multicellular organism growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1470">
        <property type="entry name" value="FTO C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032868">
        <property type="entry name" value="FTO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024366">
        <property type="entry name" value="FTO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038413">
        <property type="entry name" value="FTO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024367">
        <property type="entry name" value="FTO_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31291">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31291:SF2">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12934">
        <property type="entry name" value="FTO_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12933">
        <property type="entry name" value="FTO_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01223">
        <property type="entry name" value="FTO_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase FTO catalytic" evidence="24">
        <location>
            <begin position="12"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00046452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00049565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM01223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ABO99101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="419" mass="48348" checksum="8184EEF2BC0D3DD4" modified="2007-05-15" version="1">MSPSSSVLEPEDGEPFARVHRAHYRGFVVDAPSVLPASLHDDVERAFDDMRSRGEFTHDVVSAGNKVSTTYVRRCLLGEDGMTYHYQKLRLFAQPWRGREAYEVVRRLNETLTRSARERCEKLGGAFAESECEYNVTLINYMETEGESEIELRNEEKFDLGTTSVSWHSDSSLRENSTVAVYHTYEAPERKDWRVALRALNAECEVLCVPLEDKATYYMCGEFNATHHHAVLTGSSARYSSTHRVAVVAKDTFQYIKRRCIDALAIVPDLERENKPLDAKQIQFLADVHREVEFQWIRMFHLQGEAHAAWHDTYWTRKIAELTEAWDRMEACFRVILSKLKRSSRSPESPPRAYAMLLYALKTVKELRDEYTKRTKASAYASLPPSQRPVDLPAYDNTSPLPFELKPVIYFLEEEQNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Q5</accession>
    <name>A4S5Q5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_17608</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420813.1">
        <property type="nucleotide sequence ID" value="XM_001420776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Q5"/>
    <dbReference type="STRING" id="436017.A4S5Q5"/>
    <dbReference type="GeneID" id="5004768"/>
    <dbReference type="Gramene" id="ABO99106">
        <property type="protein sequence ID" value="ABO99106"/>
        <property type="gene ID" value="OSTLU_17608"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17608"/>
    <dbReference type="eggNOG" id="KOG2033">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013945_0_0_1"/>
    <dbReference type="OMA" id="DNPRRQT"/>
    <dbReference type="OrthoDB" id="46189at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="COG1"/>
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        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
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    </dbReference>
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        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="833" mass="92319" checksum="917BC99B30969FB4" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5R4</accession>
    <name>A4S5R4_OSTLU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420655.1">
        <property type="nucleotide sequence ID" value="XM_001420618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5R4"/>
    <dbReference type="GeneID" id="5004773"/>
    <dbReference type="Gramene" id="ABO98948">
        <property type="protein sequence ID" value="ABO98948"/>
        <property type="gene ID" value="OSTLU_26855"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26855"/>
    <dbReference type="eggNOG" id="ENOG502SSQ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109109_0_0_1"/>
    <dbReference type="OMA" id="WVSKYAR"/>
    <dbReference type="OrthoDB" id="514330at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010206">
        <property type="term" value="P:photosystem II repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.810">
        <property type="entry name" value="Photosystem II Pbs27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01481">
        <property type="entry name" value="PSII_Psb27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025585">
        <property type="entry name" value="PSII_Psb27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038450">
        <property type="entry name" value="PSII_Psb27_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13326">
        <property type="entry name" value="PSII_Pbs27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="163" mass="17702" checksum="B740682A1A53C6F0" modified="2007-05-15" version="1">MTTDAPRAEASSDRPFKEVCDPTADGADCRARILAQDAVSADTYDSKKNTFKAANASTNPNLTTYQSDTLTFLEEVEALLAKDVYDPTREKAIAVFQKKSNDWSGKYAPGGSSKMASGRAFYNALNQLAGHFSFNGLAPLPKSRLEVVETNIAKTRELIAEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5R5</accession>
    <name>A4S5R5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_17617</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GMP + ATP = GDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420656.1">
        <property type="nucleotide sequence ID" value="XM_001420619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5R5"/>
    <dbReference type="STRING" id="436017.A4S5R5"/>
    <dbReference type="GeneID" id="5004774"/>
    <dbReference type="Gramene" id="ABO98949">
        <property type="protein sequence ID" value="ABO98949"/>
        <property type="gene ID" value="OSTLU_17617"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17617"/>
    <dbReference type="eggNOG" id="KOG0707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001715_0_3_1"/>
    <dbReference type="OMA" id="NFETCYK"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000776">
        <property type="entry name" value="Guanylate kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="8">
        <location>
            <begin position="2"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="227" mass="24617" checksum="C73EC20CF67EDBB2" modified="2007-05-15" version="1">MARPLVVVGPSGVGKGTLIAMLQREFPDKFGFSVSHTTRSPRPGEVHGTHYNFVDKSTMERDIENGKFLEYAHVHQNIYGTSFAAVKTVTKSGRICLLDIDVQGAELVKKSDLNAAYVFIAPPSMEELERRLRGRGTESEDAVLKRLENARNEMAKKDVEGFFDAVIVNDDVDKAYEALKSVIAAHVETGASSASSRDAVLKYGPSAFAIACAIAIAARVFINKGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5W4</accession>
    <name>A4S5W4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_39197</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex with RFC1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420841.1">
        <property type="nucleotide sequence ID" value="XM_001420804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5W4"/>
    <dbReference type="STRING" id="436017.A4S5W4"/>
    <dbReference type="GeneID" id="5004700"/>
    <dbReference type="Gramene" id="ABO99134">
        <property type="protein sequence ID" value="ABO99134"/>
        <property type="gene ID" value="OSTLU_39197"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39197"/>
    <dbReference type="eggNOG" id="KOG0991">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_0_1_1"/>
    <dbReference type="OMA" id="SCNYSSQ"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000952">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000012">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF5">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="334" mass="36985" checksum="C94DE0FDE9E86F6A" modified="2007-05-15" version="1">MPWVEKYRPKTLDDLVGNDDAVDRMRTMVRSGFMPNLIFSGPPGCGKTSAIGVLARELLGDKYKEAVLEMNASDERGIDVVRNKIKMFAQKKVTLAPGRTKLVILDEADSMTTAAQQAMRRTMEIYSATTRFALACNTSEKVIEPIQSRCAIVRFGKLTDAQVLKRLMTVVEAEKVTYVPKGLEAIVFTADGDMRQALNNLQSTALGFGMVNEENVFRVCDQPHPNIVRDAFSFILQGNVDDAYARLKSLHDQGYSVFDIIGTMYRVCKNFDDTAMPEFIKLELIRIIGFTHLRLSEGCATMIQIGGGVARMVELVSDAKKMGGYSAELGLDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5X4</accession>
    <name>A4S5X4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420846.1">
        <property type="nucleotide sequence ID" value="XM_001420809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5X4"/>
    <dbReference type="STRING" id="436017.A4S5X4"/>
    <dbReference type="GeneID" id="5004705"/>
    <dbReference type="Gramene" id="ABO99139">
        <property type="protein sequence ID" value="ABO99139"/>
        <property type="gene ID" value="OSTLU_26913"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26913"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_490393_0_0_1"/>
    <dbReference type="OMA" id="WEYSHAS"/>
    <dbReference type="OrthoDB" id="498970at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055164">
        <property type="entry name" value="EDR1/CTR1/ARMC3-like_pept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36335">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36335:SF1">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14381">
        <property type="entry name" value="EDR1_CTR1_ARMC3_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="495"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="421"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="556" mass="60726" checksum="399E2E798652D195" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Z8</accession>
    <name>A4S5Z8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PARP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420698.1">
        <property type="nucleotide sequence ID" value="XM_001420661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Z8"/>
    <dbReference type="GeneID" id="5004717"/>
    <dbReference type="Gramene" id="ABO98991">
        <property type="protein sequence ID" value="ABO98991"/>
        <property type="gene ID" value="OSTLU_26937"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26937"/>
    <dbReference type="HOGENOM" id="CLU_1158028_0_0_1"/>
    <dbReference type="OMA" id="YAYAICY"/>
    <dbReference type="OrthoDB" id="10581774at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="26270" checksum="9C840CA0DC7D03E7" modified="2007-05-15" version="1">MPPKDPSKNNYAILYGKSAAGAQCKAGSKCSNETSPGKIILGQLRWDSKSDRFSASYHLGCVSEQSALNYLEKWRLEHPGEEDAGAVDDFPGLKELKDEHVDDVKACLENLLLGDGVDAEQREWLETVSGGDVAAAKKKAPAKKKPAPKKKPAPKKKTTKAKEPAKKRKAPAKKSAPAKKKPAAKKKKKVEEEEAEDDEAEEEEEIEEEEAEAEDAEDAEEEEDEDEEDEEEAEIASPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6D8</accession>
    <name>A4S6D8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_17798</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421076.1">
        <property type="nucleotide sequence ID" value="XM_001421039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6D8"/>
    <dbReference type="STRING" id="436017.A4S6D8"/>
    <dbReference type="GeneID" id="5005132"/>
    <dbReference type="Gramene" id="ABO99369">
        <property type="protein sequence ID" value="ABO99369"/>
        <property type="gene ID" value="OSTLU_17798"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17798"/>
    <dbReference type="eggNOG" id="KOG1151">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_85_2_1"/>
    <dbReference type="OMA" id="ECCKGTD"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060147">
        <property type="term" value="P:regulation of post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd13990">
        <property type="entry name" value="STKc_TLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000698">
        <property type="entry name" value="Serine/threonine-protein kinase tousled-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF23">
        <property type="entry name" value="TOUSLED-LIKE KINASE, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="136"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="419" mass="47553" checksum="153D07683E1309C7" modified="2007-05-15" version="1">MQIAEEGLRLGTIGVQRVGSVLQEVWEDGRAFHELDDRLDRLTESRKLAEEKRKQVKKKLPPPGSAEMDTTAHAEYVLSEEVHKARMAIIRKEEEALKSERESLEREKAAHIRALKRVRDEDGSRFNKHPVLGDRYVLMNLLGRGGFSEVYKAWDSVEMREVACKLHQLNPQWSEERKRTYVRHAARECDIHKSLDHPHVVRLIDVFEVDSDSFCTVLELCTGDDLDARLKAQGSISEREARAILAQVFNGLAYMSTGPKRIIHYDLKPGNILFDEAGRVKITDFGLSKIMEERSVGFGADSGMELTSQGAGTYWYLPPECFETGPAPPKISSKVDTWSCGVILFQMIYGKRPFGHDMSQEQILHAGTIRNAKEVEFPSRPSISLEGKAFISRCLAYKQSQRPDVLEASKDPYMTFLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="107" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6H9</accession>
    <name>A4S6H9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcriptional adapter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">HXA3501</name>
        <name evidence="17" type="ORF">OSTLU_51202</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420946.1">
        <property type="nucleotide sequence ID" value="XM_001420909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6H9"/>
    <dbReference type="STRING" id="436017.A4S6H9"/>
    <dbReference type="GeneID" id="5004953"/>
    <dbReference type="Gramene" id="ABO99239">
        <property type="protein sequence ID" value="ABO99239"/>
        <property type="gene ID" value="OSTLU_51202"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51202"/>
    <dbReference type="eggNOG" id="KOG0457">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018273_3_0_1"/>
    <dbReference type="OMA" id="ISPACYI"/>
    <dbReference type="OrthoDB" id="270417at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000087">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000115">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016827">
        <property type="entry name" value="Ada2/TADA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025024">
        <property type="entry name" value="Transcriptional_adaptor_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="13">
        <location>
            <begin position="28"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="15">
        <location>
            <begin position="86"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="16">
        <location>
            <begin position="89"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="12">
        <location>
            <begin position="91"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="14">
        <location>
            <begin position="370"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="460"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="479"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO99239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="515" mass="59650" checksum="28114556C2EE32AD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6M2</accession>
    <name>A4S6M2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_27170</name>
        <name evidence="7" type="ORF">OSTLU_29739</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420972.1">
        <property type="nucleotide sequence ID" value="XM_001420935.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422922.1">
        <property type="nucleotide sequence ID" value="XM_001422885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6M2"/>
    <dbReference type="STRING" id="436017.A4S6M2"/>
    <dbReference type="GeneID" id="5004970"/>
    <dbReference type="GeneID" id="5006899"/>
    <dbReference type="Gramene" id="ABO99265">
        <property type="protein sequence ID" value="ABO99265"/>
        <property type="gene ID" value="OSTLU_27170"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01281">
        <property type="protein sequence ID" value="ABP01281"/>
        <property type="gene ID" value="OSTLU_29739"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27170"/>
    <dbReference type="KEGG" id="olu:OSTLU_29739"/>
    <dbReference type="HOGENOM" id="CLU_013137_21_5_1"/>
    <dbReference type="OMA" id="PRDITRM"/>
    <dbReference type="OrthoDB" id="498621at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP01281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="59" mass="6728" checksum="7F3BF1BAA5C645C3" modified="2007-05-15" version="1">MKCSICFDCYATDEVVVAMPCSASHVFHERCVKEWLARDDSCPLCRSSLPVWLGRPQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="121" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6X9</accession>
    <name>A4S6X9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome b-c1 complex subunit Rieske, mitochondrial</fullName>
            <ecNumber evidence="12">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_36665</name>
        <name evidence="15" type="ORF">OSTLU_41673</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="12">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="12"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421020.1">
        <property type="nucleotide sequence ID" value="XM_001420983.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422876.1">
        <property type="nucleotide sequence ID" value="XM_001422839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6X9"/>
    <dbReference type="STRING" id="436017.A4S6X9"/>
    <dbReference type="GeneID" id="5004944"/>
    <dbReference type="GeneID" id="5006841"/>
    <dbReference type="Gramene" id="ABO99313">
        <property type="protein sequence ID" value="ABO99313"/>
        <property type="gene ID" value="OSTLU_41673"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01235">
        <property type="protein sequence ID" value="ABP01235"/>
        <property type="gene ID" value="OSTLU_36665"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36665"/>
    <dbReference type="KEGG" id="olu:OSTLU_41673"/>
    <dbReference type="eggNOG" id="KOG1671">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_0_1_1"/>
    <dbReference type="OMA" id="INAYTHT"/>
    <dbReference type="OrthoDB" id="1637982at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03470">
        <property type="entry name" value="Rieske_cytochrome_bc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit Rieske, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004192">
        <property type="entry name" value="Rieske_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02921">
        <property type="entry name" value="UCR_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81502">
        <property type="entry name" value="ISP transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="97"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO99313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABP01235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="190" mass="20720" checksum="9FB12050AB3AAFDC" modified="2007-05-15" version="1" fragment="single">AVKTPAHTIDYDVSNHTVARAGDPDKRAFTYFVMTGGRMIYASALRLAVLKFLLSMSATADVLALASLEVDLSKVELGSTVTVKWRGKPVFIRRRTPAEIAKEESVDVASLRDPQADSERAPNQEWLVAVGVCTHLGCVPIANAGDYNGWFCPCHGSHYDASGRIRKGPAPENLEIPEYKFLDGDKMLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S761</accession>
    <name>A4S761_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421398.1">
        <property type="nucleotide sequence ID" value="XM_001421361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S761"/>
    <dbReference type="STRING" id="436017.A4S761"/>
    <dbReference type="GeneID" id="5005484"/>
    <dbReference type="Gramene" id="ABO99691">
        <property type="protein sequence ID" value="ABO99691"/>
        <property type="gene ID" value="OSTLU_93669"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93669"/>
    <dbReference type="HOGENOM" id="CLU_1257588_0_0_1"/>
    <dbReference type="OMA" id="WFGEVMQ"/>
    <dbReference type="OrthoDB" id="67296at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097196">
        <property type="term" value="C:Shu complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28653">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28653:SF1">
        <property type="entry name" value="ATPASE SWSAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13481">
        <property type="entry name" value="AAA_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="222" mass="24892" checksum="1EACE9328A21E0E8" modified="2007-05-15" version="1">MHPRAFAEPLDAATRAETSERAQTRVVLVGPPECGKTTLLLRFCVRYVRENPDGRVLYIASERAMDRARVHATRDELLKDDPRALDRIGIKYAEDDQDVRALCCFRHAAPANAQPTAYVVDDLGSLIKCGGKDRVKREIAYAKTLAALHESARDDESGEERLVVVSERRDEELGGVPMGYVYARWFGEVMQACEVGNGEWDLVRQSDMASVRYSTRSSARTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4S793</accession>
    <name>A4S793_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421230.1">
        <property type="nucleotide sequence ID" value="XM_001421193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S793"/>
    <dbReference type="GeneID" id="5005350"/>
    <dbReference type="Gramene" id="ABO99523">
        <property type="protein sequence ID" value="ABO99523"/>
        <property type="gene ID" value="OSTLU_27397"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27397"/>
    <dbReference type="HOGENOM" id="CLU_1743594_0_0_1"/>
    <dbReference type="OrthoDB" id="10625154at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="150" mass="15458" checksum="389BF34A7BDEE078" modified="2007-05-15" version="1">MDAPDAVAPTHAVAGAANVGACGAAHATTLEALDRRPDARGATTHAVAGACVGTGAAWVRWGRRAATAGAACGAAAAGGARACATALEGAGERGYEFPRWFPVQIVREEGREDELLALMGRAQRGELSAEDEARTRDAYARWKMRRAGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7I5</accession>
    <name>A4S7I5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">p-ATPase family transporter: cadmium ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_43082</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421458.1">
        <property type="nucleotide sequence ID" value="XM_001421421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7I5"/>
    <dbReference type="STRING" id="436017.A4S7I5"/>
    <dbReference type="GeneID" id="5005327"/>
    <dbReference type="Gramene" id="ABO99751">
        <property type="protein sequence ID" value="ABO99751"/>
        <property type="gene ID" value="OSTLU_43082"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43082"/>
    <dbReference type="eggNOG" id="KOG0207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_6_3_1"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051949">
        <property type="entry name" value="Cation_Transport_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43079:SF1">
        <property type="entry name" value="CADMIUM_ZINC-TRANSPORTING ATPASE HMA1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43079">
        <property type="entry name" value="PROBABLE CADMIUM/ZINC-TRANSPORTING ATPASE HMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="589"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="12">
        <location>
            <begin position="94"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="632" mass="66298" checksum="CA36D69F7053841E" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S832</accession>
    <name>A4S832_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421689.1">
        <property type="nucleotide sequence ID" value="XM_001421652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S832"/>
    <dbReference type="STRING" id="436017.A4S832"/>
    <dbReference type="GeneID" id="5005663"/>
    <dbReference type="Gramene" id="ABO99982">
        <property type="protein sequence ID" value="ABO99982"/>
        <property type="gene ID" value="OSTLU_18262"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18262"/>
    <dbReference type="eggNOG" id="KOG2275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_349647_0_0_1"/>
    <dbReference type="OrthoDB" id="498904at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="806" mass="88374" checksum="CBD1A72FC160A86F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8E2</accession>
    <name>A4S8E2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Exonuclease 1</fullName>
            <ecNumber evidence="10">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_5620</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">5'-&gt;3' double-stranded DNA exonuclease which may also possess a cryptic 3'-&gt;5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="10"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421753.1">
        <property type="nucleotide sequence ID" value="XM_001421716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8E2"/>
    <dbReference type="STRING" id="436017.A4S8E2"/>
    <dbReference type="GeneID" id="5005690"/>
    <dbReference type="Gramene" id="ABP00047">
        <property type="protein sequence ID" value="ABP00047"/>
        <property type="gene ID" value="OSTLU_5620"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5620"/>
    <dbReference type="eggNOG" id="KOG2518">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008978_3_0_1"/>
    <dbReference type="OMA" id="DCITTED"/>
    <dbReference type="OrthoDB" id="26491at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09901">
        <property type="entry name" value="H3TH_FEN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09857">
        <property type="entry name" value="PIN_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000111">
        <property type="entry name" value="Exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044752">
        <property type="entry name" value="PIN-like_EXO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF8">
        <property type="entry name" value="EXONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0228">DNA excision</keyword>
    <keyword evidence="8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="6 10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="12">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="11">
        <location>
            <begin position="153"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU910737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="333" mass="37016" checksum="09CD1B67DE413A81" modified="2007-05-15" version="1" fragment="single">MGIKGLPAVLEPYCERVHVGEYAPGTRCAVDAYSWLHKGAFGCVDALAPGGDRAWERRPGATAPYVKYAVHRANMLRHHGIEPVIVFDGDRAPAKRGEERARRERRAALLERGERARAAGDKEGAFRAFSGAIDVTPEMARELIVALKREKFEFVVAPYEADATIASLALTAKERGGVDLVFTEDSDLVAYGCPRVVFKLEKSGDAKELRLATNKPKSKGPPPLDFTGWDYELFLSLCVLSGCDFLDNIRGLGIKKMYNILNKHRCVDAVFAELRANEKIKDLIAEGYEVEWRKARMIFKHALVWDPHAGALRHLTPVPEHCEFANDLSFLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8J6</accession>
    <name>A4S8J6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CobW C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_40657</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421634.1">
        <property type="nucleotide sequence ID" value="XM_001421597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8J6"/>
    <dbReference type="STRING" id="436017.A4S8J6"/>
    <dbReference type="GeneID" id="5005743"/>
    <dbReference type="Gramene" id="ABO99927">
        <property type="protein sequence ID" value="ABO99927"/>
        <property type="gene ID" value="OSTLU_40657"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40657"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_0_1_1"/>
    <dbReference type="OMA" id="KHVFQGV"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF62">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="6">
        <location>
            <begin position="239"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="404" mass="44693" checksum="F9F5555F2C67F707" modified="2007-05-15" version="1">MADEQDQTSRVPVTILTGFLGSGKTTLLNEILESETHGLRFAVIENEFGEVGVDERILSEKADEEIIEVMNGCICCTVRGDLVVALKKLYSKIAQFDAVIIETTGLADPAPVAQTFFVDDDIREKFVLDGIITVTDAKHILTRLDDEKPEGVENEAAEQVAFADRILLNKTDLVSEDELETITGRIKQINPSADIFRCQYSKVDPKNLIGINSFSLEKTLKMDPEFLNTEGEHEHDPTVSSTSTKFSGHLNINKLERWIGEIIQTMGADLFRYKGVLSVAGMDQKFVFQGVGMLFSGGFVDAKWGADEERECRFVFIGKNLDKDALINGFMDCKCSSKLRFKVGDAVLAQVGAADNDGYCRGTVRKTWDSGNPYQIELEDGKKTKVWGPVDEDEFVKASLSATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8M0</accession>
    <name>A4S8M0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_27896</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421646.1">
        <property type="nucleotide sequence ID" value="XM_001421609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8M0"/>
    <dbReference type="STRING" id="436017.A4S8M0"/>
    <dbReference type="GeneID" id="5005792"/>
    <dbReference type="Gramene" id="ABO99939">
        <property type="protein sequence ID" value="ABO99939"/>
        <property type="gene ID" value="OSTLU_27896"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27896"/>
    <dbReference type="eggNOG" id="KOG0333">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_3_1"/>
    <dbReference type="OMA" id="DFQQKGG"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="99"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="390"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="520"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="528"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="560" mass="59957" checksum="788F4DB843EB0CD3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8M9</accession>
    <name>A4S8M9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GINS subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421793.1">
        <property type="nucleotide sequence ID" value="XM_001421756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8M9"/>
    <dbReference type="STRING" id="436017.A4S8M9"/>
    <dbReference type="GeneID" id="5005761"/>
    <dbReference type="Gramene" id="ABP00087">
        <property type="protein sequence ID" value="ABP00087"/>
        <property type="gene ID" value="OSTLU_27905"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27905"/>
    <dbReference type="HOGENOM" id="CLU_1257590_0_0_1"/>
    <dbReference type="OMA" id="ERWRYGR"/>
    <dbReference type="OrthoDB" id="10251744at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="23781" checksum="309B00C06E86E0DB" modified="2007-05-15" version="1">MRRDYYDIDDFLAREHAVTVEFAWGAATVGPEVIGPKAKKDSNGRADVPKEHRAPVPLWWLDGEMAKDVYICETPAAFADDVFALLKAEDGAKITNLRTTCESYFGFARATLDALERDAGDDAEAMEPVIELKEKISDALERRWREVLVDSIGRVGDDDKTERLLSREERRIWDAGRMAQAEYERWRYGRSGRVVATKAVLDNKRQKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8T0</accession>
    <name>A4S8T0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_93830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421811.1">
        <property type="nucleotide sequence ID" value="XM_001421774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8T0"/>
    <dbReference type="STRING" id="436017.A4S8T0"/>
    <dbReference type="GeneID" id="5005973"/>
    <dbReference type="Gramene" id="ABP00105">
        <property type="protein sequence ID" value="ABP00105"/>
        <property type="gene ID" value="OSTLU_93830"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93830"/>
    <dbReference type="eggNOG" id="ENOG502SG5S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_819763_0_0_1"/>
    <dbReference type="OMA" id="HGYWGAR"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="69"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="341" mass="36574" checksum="F9B12813EA108997" modified="2007-05-15" version="1">MCGYFDEFSAGLAPAYAFSTPWSEGLVADATWVRGVGDYKKAKKEANAPVLAVSDGPGVSHAYMSALETLSGEVGGAREVFLYDQRGCGKSKSATDGEVYDLDLYLNELRTVVRELRLVEEGGAHVLAHGYWGARLATAMALERPNFAKTLTLVSPTASRATEVRDWRRALDDISPESRNVILAYEADLDDSKRDAYDAGMREFSSRFVSTRGAAGACFDVALAPRTSDAQRLAITGGRYFTASGSLASDSIQLDDLGSRLGANGVRAVRVVRGANDAVSESSAKEIVNAINANDGEPFCAYDEVSNAGSCVFLDRGDYFYESLNVCVELAEDESGGARRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8X9</accession>
    <name>A4S8X9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421837.1">
        <property type="nucleotide sequence ID" value="XM_001421800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8X9"/>
    <dbReference type="GeneID" id="5006008"/>
    <dbReference type="Gramene" id="ABP00131">
        <property type="protein sequence ID" value="ABP00131"/>
        <property type="gene ID" value="OSTLU_28004"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28004"/>
    <dbReference type="eggNOG" id="ENOG502SY94">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1646535_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="161" mass="17833" checksum="145F373B2403A897" modified="2007-05-15" version="1">MPPSICRPLVYTSWFPLAPACAAMARAPRDARARGLAALSAALIVSSFGHWRAPKWDSPRRYFDLFVVWASVGYGCWLATTMEWAYARGWWCGMPLVGAAFVANETAFHRELRAWKTCGGATRAHRWFIYRRTTWTHLVGVHAGSSTAATWLALGVAGSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S928</accession>
    <name>A4S928_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_37791</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421861.1">
        <property type="nucleotide sequence ID" value="XM_001421824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S928"/>
    <dbReference type="STRING" id="436017.A4S928"/>
    <dbReference type="GeneID" id="5006033"/>
    <dbReference type="Gramene" id="ABP00155">
        <property type="protein sequence ID" value="ABP00155"/>
        <property type="gene ID" value="OSTLU_37791"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37791"/>
    <dbReference type="eggNOG" id="KOG3057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133964_2_0_1"/>
    <dbReference type="OMA" id="NEWIAKW"/>
    <dbReference type="OrthoDB" id="1107506at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00926">
        <property type="entry name" value="Cyt_c_Oxidase_VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.140">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036549">
        <property type="entry name" value="CX6/COA6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003213">
        <property type="entry name" value="Cyt_c_oxidase_su6B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281:SF8">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 12, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome c oxidase subunit h"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="8790" checksum="77C3C9E8CE8A957D" modified="2007-05-15" version="1" fragment="single">QLKTTPFDPRFPQTNQAKHCYTRYNEFHKCQAENGEGAEECEPLAKFYRSICPTEWTEKWNEEREEGTWPGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S962</accession>
    <name>A4S962_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_28090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421880.1">
        <property type="nucleotide sequence ID" value="XM_001421843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S962"/>
    <dbReference type="GeneID" id="5006048"/>
    <dbReference type="Gramene" id="ABP00174">
        <property type="protein sequence ID" value="ABP00174"/>
        <property type="gene ID" value="OSTLU_28090"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28090"/>
    <dbReference type="eggNOG" id="ENOG502SCKS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1449924_0_0_1"/>
    <dbReference type="OrthoDB" id="544997at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043124">
        <property type="term" value="P:negative regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="21365" checksum="1485ADF726D67250" modified="2007-05-15" version="1">MGRDRNASDGVDVVQGTGAFGYGGYQEGVGYEDARARAEAERAEREKWARWEAEDEERESRKAEKKAEKKAEDRAKKEKSRARRWQKYDEAWARLDADSGASSEPLRYADVPWPPKMKELLDREAGGASATDRERKLAYHRCVKRWHPDKFLARFRARLRADDAERVVERVEAVAKSLTIAYAASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S994</accession>
    <name>A4S994_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongator complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_89433</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
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    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421896.1">
        <property type="nucleotide sequence ID" value="XM_001421859.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S994"/>
    <dbReference type="GeneID" id="5006064"/>
    <dbReference type="Gramene" id="ABP00190">
        <property type="protein sequence ID" value="ABP00190"/>
        <property type="gene ID" value="OSTLU_89433"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89433"/>
    <dbReference type="eggNOG" id="KOG1920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001477_0_0_1"/>
    <dbReference type="OMA" id="WRESLYC"/>
    <dbReference type="OrthoDB" id="40048at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056167">
        <property type="entry name" value="A-sol_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056164">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056165">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056169">
        <property type="entry name" value="HB_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056166">
        <property type="entry name" value="TPR_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23925">
        <property type="entry name" value="A-sol_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04762">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23797">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23936">
        <property type="entry name" value="HB_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23878">
        <property type="entry name" value="TPR_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017233">
        <property type="entry name" value="IKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="8">
        <location>
            <begin position="83"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="8">
        <location>
            <begin position="177"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 N-terminal second beta-propeller" evidence="9">
        <location>
            <begin position="377"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="11">
        <location>
            <begin position="795"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 TPR" evidence="10">
        <location>
            <begin position="1042"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 three-helical bundle" evidence="12">
        <location>
            <begin position="1208"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1266"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1308"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1308"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1319"/>
            <end position="1331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1448" mass="154406" checksum="4EB58CF2C75CA59E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9B5</accession>
    <name>A4S9B5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">SNF2 family DNA-dependent ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CHR3504</name>
        <name evidence="11" type="ORF">OSTLU_37662</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
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        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="EnsemblPlants"/>
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    <dbReference type="GO" id="GO:0009294">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:retrotransposition"/>
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        <property type="project" value="EnsemblPlants"/>
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    </dbReference>
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        <property type="entry name" value="lymphoid-specific helicase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Helicase_C-like"/>
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    </dbReference>
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        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
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        <property type="entry name" value="SNF2_N"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="34"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="357"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP00329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="66554" checksum="3C8FCFF58AB1E24F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9E4</accession>
    <name>A4S9E4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_4077</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422049.1">
        <property type="nucleotide sequence ID" value="XM_001422012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9E4"/>
    <dbReference type="STRING" id="436017.A4S9E4"/>
    <dbReference type="GeneID" id="5006089"/>
    <dbReference type="Gramene" id="ABP00343">
        <property type="protein sequence ID" value="ABP00343"/>
        <property type="gene ID" value="OSTLU_4077"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4077"/>
    <dbReference type="eggNOG" id="KOG2214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009031_5_1_1"/>
    <dbReference type="OMA" id="TRWILNI"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07231">
        <property type="entry name" value="Pat_SDP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF10">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="106"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
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            <end position="115"/>
        </location>
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        <location>
            <begin position="137"/>
            <end position="141"/>
        </location>
    </feature>
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        <location>
            <position position="139"/>
        </location>
    </feature>
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        <location>
            <position position="294"/>
        </location>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="434"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP00343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="434" mass="49115" checksum="6368A9F8955C5775" modified="2007-05-15" version="1" fragment="single">SRSYDVELIDEQLRQLQAQRASGNVEEMMFLLRADILRNLGSLQSDCKVRFSKSNAEPPAVPRAVRQYMAELKSQLFSIAQDETVTIQEKLVFLQETRHCFGRTALMMSGGGTLGTFHVGVARALNRKHLLPRVLAGSSVGSIIAAIIGSRTQEELDEFFSEEHFWDLLPDLTFFSGNDSMSAMKHYLRTGALHDIDFFQRCLRALLGDLTFQEAYDRSGGRILSVCVCATTTGEKPRLLNYLTSPHVVLWSAVAASCAFPSLFPPQPLLAKSRSGAFVPWLPEGKLGPRRWRDGSLEADLPMDNLRELFNCNYFIVSQTNPHIVPLLRVKRWFTSRGSALALWAYFIESEWKHRCRQVLDLIPGVDVFDVFKLFGQQWEGDATAVMWYTWKQFSHIASNPTREFLFETATMGEKEIWPQLAAIEHACGIELVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Q8</accession>
    <name>A4S9Q8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">VIC family transporter: calcium ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_28283</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="OMA" id="EWHITML"/>
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        <property type="component" value="Chromosome 17"/>
    </dbReference>
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        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
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        <location>
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            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <end position="135"/>
        </location>
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        </location>
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            <end position="547"/>
        </location>
    </feature>
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            <end position="582"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="919"/>
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        </location>
    </feature>
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            <begin position="998"/>
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        </location>
    </feature>
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            <end position="1136"/>
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        <location>
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            <end position="1250"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
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            <end position="1279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
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            <end position="1340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1419"/>
            <end position="1440"/>
        </location>
    </feature>
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            <begin position="3"/>
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        </location>
    </feature>
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        </location>
    </feature>
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            <end position="1145"/>
        </location>
    </feature>
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        <location>
            <begin position="1201"/>
            <end position="1446"/>
        </location>
    </feature>
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        <location>
            <begin position="1538"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1597"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1693"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1560"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1609"/>
            <end position="1619"/>
        </location>
    </feature>
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        <location>
            <begin position="1620"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1693"/>
            <end position="1703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023303"/>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP00531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1742" mass="192499" checksum="3BCB364F64E49CC4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Y5</accession>
    <name>A4S9Y5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_93954</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:transcription factor TFIIIC complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GTF3C_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15052:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15052">
        <property type="entry name" value="RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="539" mass="57174" checksum="A98738E8DBC91C51" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA45</accession>
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    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_28422</name>
        <name evidence="6" type="ORF">OSTLU_28498</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422245.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422350.1">
        <property type="nucleotide sequence ID" value="XM_001422313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA45"/>
    <dbReference type="GeneID" id="5006340"/>
    <dbReference type="GeneID" id="5006341"/>
    <dbReference type="Gramene" id="ABP00599">
        <property type="protein sequence ID" value="ABP00599"/>
        <property type="gene ID" value="OSTLU_28422"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP00667">
        <property type="protein sequence ID" value="ABP00667"/>
        <property type="gene ID" value="OSTLU_28498"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28422"/>
    <dbReference type="KEGG" id="olu:OSTLU_28498"/>
    <dbReference type="eggNOG" id="ENOG502SCH1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_910271_0_0_1"/>
    <dbReference type="OrthoDB" id="529273at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016763">
        <property type="term" value="F:pentosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF124">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="4">
        <location>
            <begin position="135"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="306" mass="34896" checksum="C3F463C1F9A12BC9" modified="2007-05-15" version="1">MSKFHQLPLRAYVDVKVDPVIFTHALNKNHTSNLFVIAPDDKRGANPFHFAQSAMFFFHSALRTLENSDSSSVVIIFRQRPPAQSWIDSLTQQIFGDVRVVYGDELTSPICARRVVVAGTMIGLLQGPYDAQLFRDRVYGNLKINPKRINRADLRVTLIDRKKRRVTNVGELQEILDERRLWYKTVRLDTLSFKEQVSLMSETDLLISSHGADLTNVIFMQRESAVIELFPSTVWYYELYAKIARNAGLFHTYALGDQTHAVTKTIAECFESACLTELKRDFMIPPERFRTSLDHALSLLGVANAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA68</accession>
    <name>A4SA68_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422293.1">
        <property type="nucleotide sequence ID" value="XM_001422256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA68"/>
    <dbReference type="STRING" id="436017.A4SA68"/>
    <dbReference type="GeneID" id="5006385"/>
    <dbReference type="Gramene" id="ABP00610">
        <property type="protein sequence ID" value="ABP00610"/>
        <property type="gene ID" value="OSTLU_28448"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28448"/>
    <dbReference type="HOGENOM" id="CLU_1513012_0_0_1"/>
    <dbReference type="OrthoDB" id="283575at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="178" mass="19223" checksum="AC49A27E47218657" modified="2007-05-15" version="1">MRATNAELKTRLDALNTTDVEMKAKDTELSGRIDALNATDTELKTADALLGSRIDALNTTDAALKAEDANLSNRIDILNATDAVLKGVDDGLSSRIDALTNIYVNELNLTDEQLIVTDATLGSRIDRLNETQYELKGMDAGLSIRIDALDDSKAELQRVDTEVAAVIASLNTMGEELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA89</accession>
    <name>A4SA89_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422342.1">
        <property type="nucleotide sequence ID" value="XM_001422305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA89"/>
    <dbReference type="GeneID" id="5006399"/>
    <dbReference type="Gramene" id="ABP00659">
        <property type="protein sequence ID" value="ABP00659"/>
        <property type="gene ID" value="OSTLU_28474"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28474"/>
    <dbReference type="eggNOG" id="KOG4533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048479_0_0_1"/>
    <dbReference type="OMA" id="HYPETIT"/>
    <dbReference type="OrthoDB" id="4347at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055323">
        <property type="entry name" value="C57A10.07/YOR238W"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28110">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28110:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="29233" checksum="740DD4F63F87F6FA" modified="2007-05-15" version="1">MRLSAQEKKIVPAVTDVDELVVVPARAVYLGSDFAKAAEDPGDWALERDQTSSEGYVRSLVEHIEIGVREAARNPHAVLVFSGGKSIDAGAVMTRASSYWQVARANDWFGVDAKVESRTFTEEHANDGFEHALFSVCRFFQLARKFPSKITVVGFHVERARFEKLHLDAMGYSWSNMTYIGTAAVNENELATREAKACDAFARDPYGCRNDVGSTGQALDPFNERASYSSTVKSLKSFWTYLDACPRRRFAGRFPWSPGVALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAL4</accession>
    <name>A4SAL4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_25814</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422632.1">
        <property type="nucleotide sequence ID" value="XM_001422595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAL4"/>
    <dbReference type="STRING" id="436017.A4SAL4"/>
    <dbReference type="GeneID" id="5006689"/>
    <dbReference type="Gramene" id="ABP00949">
        <property type="protein sequence ID" value="ABP00949"/>
        <property type="gene ID" value="OSTLU_25814"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25814"/>
    <dbReference type="eggNOG" id="KOG0817">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1534593_0_0_1"/>
    <dbReference type="OMA" id="YSGEHKM"/>
    <dbReference type="OrthoDB" id="548600at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF15">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="85"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="180" mass="19520" checksum="3F7F19D6A1801CD0" modified="2007-05-15" version="1">MPARTSRGVGRRARPATSTMRRAVETETETETETETDAESDGDDDDDGSSTSQTELFGAIEDGDHDAFERALREDAACVKDVNSNGWTAAHQAAYSGEHKMLRRVLELGVDVNARCADGCLAAHYASAQGEKKCLQVLGELGSEFETKDKDGESPLDVCTRGVRELLADLIVEARKRNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAW2</accession>
    <name>A4SAW2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">fructose-bisphosphatase</fullName>
            <ecNumber evidence="6">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_25840</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the FBPase class 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="6"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422674.1">
        <property type="nucleotide sequence ID" value="XM_001422637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAW2"/>
    <dbReference type="STRING" id="436017.A4SAW2"/>
    <dbReference type="GeneID" id="5006566"/>
    <dbReference type="Gramene" id="ABP00991">
        <property type="protein sequence ID" value="ABP00991"/>
        <property type="gene ID" value="OSTLU_25840"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25840"/>
    <dbReference type="eggNOG" id="KOG1458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039977_2_2_1"/>
    <dbReference type="OMA" id="ISNDIFC"/>
    <dbReference type="OrthoDB" id="10256725at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF1">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="13">
        <location>
            <begin position="24"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="14">
        <location>
            <begin position="216"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABP00991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="36861" checksum="C43384EC41AA4117" modified="2007-05-15" version="1">MRARAALGESLSAHLASASARGDIDADLAIALNSVAIACKRVRALVARAPIAGNTGAAGGSNASGDEQKKLDVIANDVFVETLRACGRASVIVTEEEDTPIAVERASGYIVTFDPIDGSSNIDACVTTGSIFGVYAPGACEIKDTDSAEETLANCLTNSLQSGEALVAAGYCMYSSSCVFVLTTGDGVAQYDFDENVGEFVCSKERVTIPDGDKMQRIYSGNNGNVNLWAPELKDYVAHLQKGGSDGGKPWTYRYIGALIGDFHRTLLYGGIWLYPPDTSAPNGKARLLYEIAPISMIAEQAGGMSTRGPKANESVLDVVPKHIHEKSPMFVGSKSAVQDLQEFLKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAW3</accession>
    <name>A4SAW3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_8494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422508.1">
        <property type="nucleotide sequence ID" value="XM_001422471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAW3"/>
    <dbReference type="STRING" id="436017.A4SAW3"/>
    <dbReference type="GeneID" id="5006732"/>
    <dbReference type="Gramene" id="ABP00825">
        <property type="protein sequence ID" value="ABP00825"/>
        <property type="gene ID" value="OSTLU_8494"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8494"/>
    <dbReference type="eggNOG" id="ENOG502S1FT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098227_1_1_1"/>
    <dbReference type="OMA" id="RECKQRM"/>
    <dbReference type="OrthoDB" id="197940at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021511">
        <property type="entry name" value="DUF3172"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11371">
        <property type="entry name" value="DUF3172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="136" mass="14910" checksum="75BEB28F6840EB85" modified="2007-05-15" version="1" fragment="single">LIAGAFVVGIGAGVVFDTAVDLEPSNVASREILDRRTPSSELCMANGASAMVFDQRVFLSLNPFNVYVAQPEVKPGCVVRRSNWGVLERNNVVDKKAEDVCKQHLNTFAFVGDLDKSPEVSCVYHSEDAENQFMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAX8</accession>
    <name>A4SAX8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_43564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422516.1">
        <property type="nucleotide sequence ID" value="XM_001422479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAX8"/>
    <dbReference type="STRING" id="436017.A4SAX8"/>
    <dbReference type="GeneID" id="5006739"/>
    <dbReference type="Gramene" id="ABP00833">
        <property type="protein sequence ID" value="ABP00833"/>
        <property type="gene ID" value="OSTLU_43564"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43564"/>
    <dbReference type="eggNOG" id="KOG4254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019722_4_0_1"/>
    <dbReference type="OMA" id="VRGMQKF"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313:SF1">
        <property type="entry name" value="FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="554" mass="59848" checksum="8D05CE43690BFB51" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBB0</accession>
    <name>A4SBB0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">MC family transporter: peroxisomal membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_43906</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422587.1">
        <property type="nucleotide sequence ID" value="XM_001422550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBB0"/>
    <dbReference type="STRING" id="436017.A4SBB0"/>
    <dbReference type="GeneID" id="5006800"/>
    <dbReference type="Gramene" id="ABP00904">
        <property type="protein sequence ID" value="ABP00904"/>
        <property type="gene ID" value="OSTLU_43906"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43906"/>
    <dbReference type="eggNOG" id="KOG0769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_6_3_1"/>
    <dbReference type="OMA" id="QFMMYEL"/>
    <dbReference type="OrthoDB" id="2019556at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080122">
        <property type="term" value="F:AMP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005347">
        <property type="term" value="F:ATP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015228">
        <property type="term" value="F:coenzyme A transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015230">
        <property type="term" value="F:FAD transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044610">
        <property type="term" value="F:FMN transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051724">
        <property type="term" value="F:NAD transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044375">
        <property type="term" value="P:regulation of peroxisome size"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF5">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="99"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="215"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="315" mass="34207" checksum="FD4DBE240AC5830C" modified="2007-05-15" version="1">MPPVDARDDVVEAAAGTLGALLALVTTYPLITLNTRQHVTRRRERDGDDGDDAPSTSSLSSMYDGIEPALVGTACSQAVYNYWYSRANGTYRARRGRDATGAASLAIASFAGCVNVLMTLPIWTIVTKMQADTAAAKLRSATSEGGKKNGDQNGSGKKKRSFFDIAREVVRDGGVCGLWQGLTPSLVMVANPALQYAFYETVAKWRLKRDRKTTLSAPEIFVFGACAKFGATMLTYPLMVVKSRLQVVSKDMADDRMRYRGTAHAVRCMAAEEGLGVFYKGIETKLTQTILAAALMFTVKEKLAESVYAARRVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBC2</accession>
    <name>A4SBC2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422750.1">
        <property type="nucleotide sequence ID" value="XM_001422713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBC2"/>
    <dbReference type="GeneID" id="5006807"/>
    <dbReference type="Gramene" id="ABP01067">
        <property type="protein sequence ID" value="ABP01067"/>
        <property type="gene ID" value="OSTLU_29557"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29557"/>
    <dbReference type="HOGENOM" id="CLU_1279495_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672288" evidence="2">
        <location>
            <begin position="22"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="216" mass="22480" checksum="95802001C60F121A" modified="2007-05-15" version="1">MFKNLLVPFVFGLAVAHTARADAGDTCSTHTDCVVSSGYASANPWASSEEFCYNTGTYNGVTVSVCSDCFGCSAGPPPYGNSIDQSCPSKCTDTISSYTSCGTEIATEVANGAKCWDGAHGCPPLHKKGGKWCSMYTGGQNVCCGDDCCKPDGGAIAGIIIGTVVGLTLLIVSCCYCGRCGCFAYRRDQLIATAVATRPQQPQVIYVQQAPAKVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBD0</accession>
    <name>A4SBD0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422595.1">
        <property type="nucleotide sequence ID" value="XM_001422558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBD0"/>
    <dbReference type="STRING" id="436017.A4SBD0"/>
    <dbReference type="GeneID" id="5006653"/>
    <dbReference type="Gramene" id="ABP00912">
        <property type="protein sequence ID" value="ABP00912"/>
        <property type="gene ID" value="OSTLU_29564"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29564"/>
    <dbReference type="eggNOG" id="KOG0796">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030397_0_0_1"/>
    <dbReference type="OMA" id="CPHELFP"/>
    <dbReference type="OrthoDB" id="10266921at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="248"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="138"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="38424" checksum="44AEF5EB283313AA" modified="2007-05-15" version="1">MADAMRAMLDQLMGTERDVPLDQRTGRSRHYSDADVCKYYICGFDVTCFKNTKSDADVLRCVGAEAQEKVRDDGAREAFRLAPEAEKAKCGYEMDTKMVLDRMIRECDRRIERGMVRARAEKEEAMVKMATSADADTLRLLEVKMEESAAKAEKLGEEGDVDGAEAELAHLETFEQRAKEVKAKMDSMDAYRLTEPCPVSGTLLCNTDTEERRQEHLMGKQYTGWTHIRKLRDELAARLAKYEEAGFAIGGRSGGDGRDRKRRSRSPDRDRSYRPRDNRDREYGRGDRDTYRGGGDRRYEPYRDDRRRGDDRRSYDRRDDRRRDDRYRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBI9</accession>
    <name>A4SBI9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_19157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422629.1">
        <property type="nucleotide sequence ID" value="XM_001422592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBI9"/>
    <dbReference type="GeneID" id="5006837"/>
    <dbReference type="Gramene" id="ABP00946">
        <property type="protein sequence ID" value="ABP00946"/>
        <property type="gene ID" value="OSTLU_19157"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19157"/>
    <dbReference type="HOGENOM" id="CLU_807387_0_0_1"/>
    <dbReference type="OMA" id="GHTPYAE"/>
    <dbReference type="OrthoDB" id="495672at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672293" evidence="1">
        <location>
            <begin position="29"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="36311" checksum="7F7D4F1F1D6D9420" modified="2007-05-15" version="1">MMTRARGERRGAKMMALIVASLATLVRGDEYSVNIERAIVNSKGLQAVGALDALSARLLEALCESDETSCEAYETTRKSLWLTFGNDYICQVGSDADATWNAIDTTSTQGGIAVLLSKCSRAWLGDLEQAVLNLAPRFLAQASLQRADVAAVIAANDAAAGRAATQAGDNLDDLHPSYIANLAPIATELTSFSESRPVVVTATATADESTYYSGFSTDVKSAIAASRARGAKSVAGSTEAFPDAYVKRVETAQVSLDLYRGRYLEHPYAKAHYDKAIKCAGQSTNDALCYNRVVPEIGYTHSADGTRLLSSYGEPLATNFVDYNQPATYVAGVRLSSQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQF3</accession>
    <name>A4RQF3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415376.1">
        <property type="nucleotide sequence ID" value="XM_001415339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQF3"/>
    <dbReference type="GeneID" id="5000020"/>
    <dbReference type="Gramene" id="ABO93668">
        <property type="protein sequence ID" value="ABO93668"/>
        <property type="gene ID" value="OSTLU_28645"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28645"/>
    <dbReference type="HOGENOM" id="CLU_2150090_0_0_1"/>
    <dbReference type="OrthoDB" id="10574893at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="112" mass="12155" checksum="9333F002094F4083" modified="2007-05-15" version="1">MALRPEAVAIQPASASEHAFLRDNFDLLFPSTDPLDRSTFHALAKLILVRRIVKALVTDFGGVERIRRGLAEPLVIDVQVVVEGDVVFRVHTVAPKSDAVSGVGQRLGVISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQF4</accession>
    <name>A4RQF4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415377.1">
        <property type="nucleotide sequence ID" value="XM_001415340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQF4"/>
    <dbReference type="GeneID" id="4999938"/>
    <dbReference type="Gramene" id="ABO93669">
        <property type="protein sequence ID" value="ABO93669"/>
        <property type="gene ID" value="OSTLU_28646"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28646"/>
    <dbReference type="HOGENOM" id="CLU_935050_0_0_1"/>
    <dbReference type="OrthoDB" id="497700at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="298" mass="32922" checksum="153A9B75838C0FBD" modified="2007-05-15" version="1">MSPSKLRVNTQRLHRAYSSGDLGRRPKFATNVAVLLLTNVGLLSFFLGGVYFVLSGWDQTATLCVVGYVCCGLALAIPSMTFSKSLDDEKVACDDDEAKRDEDSRVLYRVFAGVLNVAGLILGILGSLLYSPGFCKWATSGRFDPYVNDADFETLTDRANVIWAISFLLFPIGSGLFLYDRKRTLEKRAALKQRRAPGYFSQELYLYTWIEIALVVFAVGGMLFCFDDNEGLLVGSLVLFFIGGGIKAGLMFHELRMFFGGTCDAMREDRDSDDSDERSPLIGDRDNMSDTSSLLGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQG3</accession>
    <name>A4RQG3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415728.1">
        <property type="nucleotide sequence ID" value="XM_001415691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQG3"/>
    <dbReference type="STRING" id="436017.A4RQG3"/>
    <dbReference type="GeneID" id="4999415"/>
    <dbReference type="Gramene" id="ABO94020">
        <property type="protein sequence ID" value="ABO94020"/>
        <property type="gene ID" value="OSTLU_92056"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92056"/>
    <dbReference type="eggNOG" id="ENOG502S6CS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_892517_0_0_1"/>
    <dbReference type="OMA" id="RMSGIQE"/>
    <dbReference type="OrthoDB" id="496922at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="34865" checksum="76E3CEE03177A683" modified="2007-05-15" version="1">MNEFERQREARIARNKSILERLIASNPAHAALHAERPTPAKPRGPRPKQPTNEADLRRSGRVRRLPAPVYTTFDVNDDLGDGVSARKRAKMTQTSSSATTKKYFSSSKREAPSANSLRALNANLWDVYANYLGEPIHPPESDRGALKAAVVHALSPVSNPKFSKMSGIQEWKNCVALYVNVGDKHGNAYDNVFTRAGSRITWFAQPRQDEDSPVIKSIMKTSTLEEESVEDAMTRAENGEEAAPKYVDWPLHLFCRMEGCEYVYCGRLKMVDVDTKKRPMKFTMRLVDAPLLRGSEHFLGLVDLADADATSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQK1</accession>
    <name>A4RQK1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_7333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415403.1">
        <property type="nucleotide sequence ID" value="XM_001415366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQK1"/>
    <dbReference type="STRING" id="436017.A4RQK1"/>
    <dbReference type="GeneID" id="4999854"/>
    <dbReference type="KEGG" id="olu:OSTLU_7333"/>
    <dbReference type="eggNOG" id="KOG1205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1850344_0_0_1"/>
    <dbReference type="OMA" id="CISEVWA"/>
    <dbReference type="OrthoDB" id="498525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="139" mass="14898" checksum="C235E6975F1F94B3" modified="2007-05-15" version="1" fragment="single">LLTMDLTKEDSIAQCIASIVERHGKIDVLINNAGVCLCSWAKQTPRDDAEMIMQTNFLGAVSVIRHAMPHLSQGANIINVGSIAGRIGIPFQSMYSASKAALMVYTDALRMETKGSGVRVSLIEPGDLRLQKGAASVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQR8</accession>
    <name>A4RQR8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_28758</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415781.1">
        <property type="nucleotide sequence ID" value="XM_001415744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQR8"/>
    <dbReference type="GeneID" id="5000022"/>
    <dbReference type="Gramene" id="ABO94073">
        <property type="protein sequence ID" value="ABO94073"/>
        <property type="gene ID" value="OSTLU_28758"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28758"/>
    <dbReference type="eggNOG" id="KOG2191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022670_1_0_1"/>
    <dbReference type="OMA" id="SIAKEPH"/>
    <dbReference type="OrthoDB" id="441329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22437">
        <property type="entry name" value="KH-I_BTR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22514">
        <property type="entry name" value="KH-I_BTR1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="43"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="126"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="252"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="35393" checksum="EAC1B7F6304DB467" modified="2007-05-15" version="1">MSSNDDGARDARGDDGNAARDADDAGGDASDDGGESAAPIDDGSFTLKFLISPSAAGSVIGKGGATINEFQALTGARIQLSRNREVFPGTNDRVVIVSGDLSAILQVLHLIITKLVADGEGIDRMGQPQVALVVPNSSCGCIIGKGGSKIRSFVEDSQADIKLSNQDRMLPGCNDRTLTITGTIDCVLRAVALVATTLCEDPAYATLVHRQSTYSVQSPLSLQGGGGGRRSGEFNRATPRRYGAGQGGGRDDETSILVTIPDSLIGAVLGRGGRTIAEVQVASGCRIKVSDRDDFFEGTRNRKVVISGSAEGVQMANYLLTQKLSAITAQMSFSGENPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR61</accession>
    <name>A4RR61_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_13763</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415843.1">
        <property type="nucleotide sequence ID" value="XM_001415806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR61"/>
    <dbReference type="STRING" id="436017.A4RR61"/>
    <dbReference type="GeneID" id="4999628"/>
    <dbReference type="Gramene" id="ABO94135">
        <property type="protein sequence ID" value="ABO94135"/>
        <property type="gene ID" value="OSTLU_13763"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13763"/>
    <dbReference type="eggNOG" id="KOG0663">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="WVARATN"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010556">
        <property type="term" value="P:regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07843">
        <property type="entry name" value="STKc_CDC2L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000533">
        <property type="entry name" value="cyclin-dependent kinase 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000172">
        <property type="entry name" value="cyclin-dependent kinase G-2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045267">
        <property type="entry name" value="CDK11/PITSLRE_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="11"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="317" mass="35734" checksum="A4236490CC8FEDC5" modified="2007-05-15" version="1">MLQACRSVDEFERLNKIDEGTYGIVFKARDKKTGEVAALKRVKMDEATDGFPLTALREVNILLSLDHPSIVNVNEVVVGSKLNFVFMVMEYVENDLKGLMDQMAQSSSPKFTIPETKALMLQLLSGMSYLHENWIMHRDLKMSNILVTNSGDLKICDFGLARQFGGVGRYTQLVVTLWYRAPELLLGSTTYGPAIDVWSLGCIFGELLAGSPLFNGRAEIDQLQKIFKLLGTPNDKIWPEFSSLPSVQKVTFAEQPYNKLRQKFPQASTGLSDKGYELLNHLLTYDPARRLTCSEALNDAFFEEYPPPQRPVFMNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR85</accession>
    <name>A4RR85_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nuclear proteasome inhibitor UBLCP1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_6029</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415855.1">
        <property type="nucleotide sequence ID" value="XM_001415818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR85"/>
    <dbReference type="STRING" id="436017.A4RR85"/>
    <dbReference type="GeneID" id="4999640"/>
    <dbReference type="Gramene" id="ABO94147">
        <property type="protein sequence ID" value="ABO94147"/>
        <property type="gene ID" value="OSTLU_6029"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6029"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046931_1_0_1"/>
    <dbReference type="OMA" id="MEDEIIM"/>
    <dbReference type="OrthoDB" id="1711508at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090364">
        <property type="term" value="P:regulation of proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011943">
        <property type="entry name" value="HAD-SF_hydro_IIID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051658">
        <property type="entry name" value="UBLCP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02245">
        <property type="entry name" value="HAD_IIID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="12">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="13">
        <location>
            <begin position="136"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="36278" checksum="3A54D5F5B3D30DB2" modified="2007-05-15" version="1" fragment="single">VSVRWSGGTPPTFDIDVDDDATVADLKRSIETTTQVRAARIKLLNLRIGAKPAMDDDALSEIGKFPKQVMMMGKRESQIEAHATAEALASSMAPEVEDDFELDARTTTAAMANPEFIAKLERRVRDCKFPKKLSDPRPGAKCLVLDIDYTLFDHRTTAENPSEIMRPFLHEFLSRAYAANFDIFIWSATSLKWIELKMTELGVLTHNDYKIVGLIDSSAMITVETAKYGVFNCKPLGYLFAQDWCEYDSKTTLMFDDLSRNFIMNPQLGLKIRPFRNAHTSRATDRELLRLSEYLEEIASLDDFSELNHNRWESFLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRB1</accession>
    <name>A4RRB1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S13, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS13</name>
        <name evidence="6" type="ORF">OSTLU_40147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415540.1">
        <property type="nucleotide sequence ID" value="XM_001415503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRB1"/>
    <dbReference type="STRING" id="436017.A4RRB1"/>
    <dbReference type="GeneID" id="4999573"/>
    <dbReference type="Gramene" id="ABO93832">
        <property type="protein sequence ID" value="ABO93832"/>
        <property type="gene ID" value="OSTLU_40147"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40147"/>
    <dbReference type="eggNOG" id="KOG0400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090139_2_0_1"/>
    <dbReference type="OMA" id="MHTRRKG"/>
    <dbReference type="OrthoDB" id="623277at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000003">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.130:FF:000001">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_uS15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_uS15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006331">
        <property type="entry name" value="PRK08561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS15 N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="152" mass="16938" checksum="10A194678690F20D" modified="2007-05-15" version="1">MGRMHTPGKGMSGSALPYKRSAPSWLKVTPTEVTEMITKMAKKGMTPSQIGVALRDNHGIAQVSSVTNSKVLRILRGQGLAPGIPEDLYCLIKKAVSVRKHLERNRKDMDSKFRLILIESRIHRLARYYKLAKKLEPSFKYNSASAATLLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRU0</accession>
    <name>A4RRU0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_92201</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415628.1">
        <property type="nucleotide sequence ID" value="XM_001415591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRU0"/>
    <dbReference type="STRING" id="436017.A4RRU0"/>
    <dbReference type="GeneID" id="4999905"/>
    <dbReference type="Gramene" id="ABO93920">
        <property type="protein sequence ID" value="ABO93920"/>
        <property type="gene ID" value="OSTLU_92201"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92201"/>
    <dbReference type="eggNOG" id="KOG1115">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_704662_0_0_1"/>
    <dbReference type="OMA" id="FAQNTRC"/>
    <dbReference type="OrthoDB" id="530923at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF54">
        <property type="entry name" value="SPHINGOSINE KINASE RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="6">
        <location>
            <begin position="43"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="353" mass="37838" checksum="3AB095C4CCF4CB5B" modified="2007-05-15" version="1">MSRAREAPTTFCGLPTLRPDAQARTRAATPETRGDARDDATRTRVRKLLLVRHGAKAKTTRGKRDAEEIRRACEAANVDVETATTERAGHGVELVRDADLSDVDAIGVVGGDGTLREAVQGWIEREASGRGDGRRTPIFAFPCGTGNNYARDLGVFTVADAMAKLKAGNARPVDAVRVSDGVGNDTISINVVTWGMARDAAETAEGMRWMGGLRYDVAGLIHILKNKKNNGIIGVSDSLEGEIVEESNDYLMMFAQNTRCSGRAFAFTPLAQLDDGFFDVVVCNKGGPMHTKALFDATKTGGGHVEDRNVSYVKAKRLSLKTAAAESVGIDGEVTVPTPVHLTALEGVFTTFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSC6</accession>
    <name>A4RSC6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nucleolar complex protein 3 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_36158</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416271.1">
        <property type="nucleotide sequence ID" value="XM_001416234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSC6"/>
    <dbReference type="STRING" id="436017.A4RSC6"/>
    <dbReference type="GeneID" id="5000470"/>
    <dbReference type="Gramene" id="ABO94564">
        <property type="protein sequence ID" value="ABO94564"/>
        <property type="gene ID" value="OSTLU_36158"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36158"/>
    <dbReference type="eggNOG" id="KOG2153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012441_4_0_1"/>
    <dbReference type="OMA" id="HYCPQVR"/>
    <dbReference type="OrthoDB" id="496971at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="7">
        <location>
            <begin position="11"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="6">
        <location>
            <begin position="318"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="607"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="618" mass="68629" checksum="FCABCADB409DC68A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSG2</accession>
    <name>A4RSG2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_4036</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416255.1">
        <property type="nucleotide sequence ID" value="XM_001416218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSG2"/>
    <dbReference type="STRING" id="436017.A4RSG2"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="5000100"/>
    <dbReference type="Gramene" id="ABO94548">
        <property type="protein sequence ID" value="ABO94548"/>
        <property type="gene ID" value="OSTLU_4036"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4036"/>
    <dbReference type="HOGENOM" id="CLU_031603_0_1_1"/>
    <dbReference type="OMA" id="MMIFASD"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="13"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="263" mass="30028" checksum="0C5F281A334E6C88" modified="2007-05-15" version="1" fragment="single">RGRAAARDVFKLARESGMTTIRAWAFSVNPAVPTWVRVGERHREDVLRGLDWALAEAAKHGLDLLLAFGDYWHTTAEIVRECAPEDAETEDADRAFFSRESCRELFKWHVRTILTRNNTFTGVTYSTTPNVFGWNLMNEPRCRGCDDALQDWIDDMAAYVKAFDSNHMLTVGEEGFYAHDSSSEGGAAANPAAWAATTGQDFIRNHASKHIDFATIHVWRDNWAVYSPNVRFNAQRFTRNWIATHERDCRTKLRKPLLIEEFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSN0</accession>
    <name>A4RSN0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_30187</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the frataxin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416215.1">
        <property type="nucleotide sequence ID" value="XM_001416178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSN0"/>
    <dbReference type="STRING" id="436017.A4RSN0"/>
    <dbReference type="GeneID" id="5000150"/>
    <dbReference type="Gramene" id="ABO94508">
        <property type="protein sequence ID" value="ABO94508"/>
        <property type="gene ID" value="OSTLU_30187"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30187"/>
    <dbReference type="eggNOG" id="KOG3413">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080880_2_1_1"/>
    <dbReference type="OMA" id="MTESEFM"/>
    <dbReference type="OrthoDB" id="1897642at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034986">
        <property type="term" value="F:iron chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017789">
        <property type="entry name" value="Frataxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03422">
        <property type="entry name" value="mito_frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="167" mass="19510" checksum="128F282371E35A04" modified="2007-05-15" version="1">MRFQLAVTKLVRRARRLQRISHVRIDSQPFITLQLSFKDERDHARPRSISQNRFSTSESKEYVFNDVANCTLQNILDSIEALIDKERLDMDISLETGVLTIDCGENGVFVLNKQTPNRQIWLASPVSGPFRYNYTPSGEWLSTRDDYSLQSRLKYELESIYKLEVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RST2</accession>
    <name>A4RST2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CopZ</name>
        <name evidence="14" type="ORF">OSTLU_119586</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416192.1">
        <property type="nucleotide sequence ID" value="XM_001416155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RST2"/>
    <dbReference type="STRING" id="436017.A4RST2"/>
    <dbReference type="GeneID" id="5000217"/>
    <dbReference type="Gramene" id="ABO94485">
        <property type="protein sequence ID" value="ABO94485"/>
        <property type="gene ID" value="OSTLU_119586"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119586"/>
    <dbReference type="eggNOG" id="KOG3343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086803_1_1_1"/>
    <dbReference type="OMA" id="NELMLHS"/>
    <dbReference type="OrthoDB" id="10249988at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000013">
        <property type="entry name" value="Coatomer subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="175" mass="19737" checksum="4ECD97BEB37CEA9E" modified="2007-05-15" version="1">MSIPSVSSIVILDDEGKRVAVKYYETLKRARDVQFTFERNLFTKSSHLSGKGEVELLILDDYIAVHKASHDLRFYVAARHDENELILVSVLETLYEALCTLLRGVVDKHAALENLDLVLLVIDELIDGGLILETDPTTIVNRVSMEESMEHSLTEQTISQALATAREQISRNLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT81</accession>
    <name>A4RT81_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PsbP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416122.1">
        <property type="nucleotide sequence ID" value="XM_001416085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT81"/>
    <dbReference type="GeneID" id="5000454"/>
    <dbReference type="Gramene" id="ABO94414">
        <property type="protein sequence ID" value="ABO94414"/>
        <property type="gene ID" value="OSTLU_92290"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92290"/>
    <dbReference type="HOGENOM" id="CLU_1478742_0_0_1"/>
    <dbReference type="OMA" id="DRACEGH"/>
    <dbReference type="OrthoDB" id="497896at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="1">
        <location>
            <begin position="27"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="19699" checksum="DA16576F577AC8BA" modified="2007-05-15" version="1" fragment="single">VAPSGSTTRANAFESSRAGGESISPYAYRLRWPSGWCALRDLASARTVGVDASFKDPLDEASTLAVFVTRGVRERDVASRYGTLDEDARRRADAAPNQKTIGKRTVRVSVPRGDGAGRVVVEAHEIETEVGGGTAGRFGAAVELIRVWVADGSEWCVRATASKSAWPRVRGELRRAVDSFEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTI6</accession>
    <name>A4RTI6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_14089</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416066.1">
        <property type="nucleotide sequence ID" value="XM_001416029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTI6"/>
    <dbReference type="STRING" id="436017.A4RTI6"/>
    <dbReference type="GeneID" id="5000415"/>
    <dbReference type="Gramene" id="ABO94358">
        <property type="protein sequence ID" value="ABO94358"/>
        <property type="gene ID" value="OSTLU_14089"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14089"/>
    <dbReference type="eggNOG" id="KOG0861">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074848_2_0_1"/>
    <dbReference type="OMA" id="MINEIYM"/>
    <dbReference type="OrthoDB" id="27923at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15867">
        <property type="entry name" value="R-SNARE_YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045848">
        <property type="entry name" value="R-SNARE_YKT6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Longin" evidence="9">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="146"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="206" mass="22917" checksum="BEAF6665D76E7DAF" modified="2007-05-15" version="1">MKVTALTLWKSNGADDDPSFLGGATDVAEFGFFQRASVREMLIFISRTVAKRTPLGARQSVQQDAYMVHVSNKSGLVAVAVMDEEYPSRSAFCVLGKMMDEYESANGEGANEAWRAVREDKPEGGRASEMLEEMLVKYQDPSAADKILKIQRELDDTKVVLHKTIDSVLARGEKLDNLVDKSTDLSLASQMFYKQAKKQNQCCTMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTN3</accession>
    <name>A4RTN3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416286.1">
        <property type="nucleotide sequence ID" value="XM_001416249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTN3"/>
    <dbReference type="GeneID" id="5000394"/>
    <dbReference type="Gramene" id="ABO94579">
        <property type="protein sequence ID" value="ABO94579"/>
        <property type="gene ID" value="OSTLU_14059"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14059"/>
    <dbReference type="HOGENOM" id="CLU_1954299_0_0_1"/>
    <dbReference type="OMA" id="NKRNEGS"/>
    <dbReference type="OrthoDB" id="511222at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019034">
        <property type="entry name" value="UPF0390"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36769">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-DEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36769:SF1">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-DEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09495">
        <property type="entry name" value="DUF2462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="130" mass="14165" checksum="E321E6063F1D6435" modified="2007-05-15" version="1">MPQGQTLKSKAKRATGRVGAGKTKKVAANRHGKVIKQRKGKFAFSPSSTASVVSRHKQNADITRQVNEKNELEFSRRATASGGTFRLLKAPEGVELGEANRGPKPKKRAKPVVKTPAQLQAEKNASKWSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTN8</accession>
    <name>A4RTN8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_30328</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416820.1">
        <property type="nucleotide sequence ID" value="XM_001416783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTN8"/>
    <dbReference type="GeneID" id="5000857"/>
    <dbReference type="Gramene" id="ABO95113">
        <property type="protein sequence ID" value="ABO95113"/>
        <property type="gene ID" value="OSTLU_30328"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30328"/>
    <dbReference type="eggNOG" id="KOG1188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037323_4_2_1"/>
    <dbReference type="OMA" id="NDGPVAF"/>
    <dbReference type="OrthoDB" id="25131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="390" mass="41375" checksum="075AE9FEB819400D" modified="2007-05-15" version="1">MTSTAVDKDAPYNTHIASNHDGTSCAVATTSGRVRVYARERATGAFAHGEREIRLNASVNECEFGSAADPFSIVCACGDGTTRVYDARSQDDRPTASFRAPFNERDVASASLGGSASDFLVATAVGPHVAFYDRRQQGNASLFQDAHSEAVTRVRFHPERRSELYTSSVDGLVCAFDCAHTPLNDEESLISVMSAEAAVNNIGFCRSGSSGDARDALWCVTGVEDAHIFVASSDRRRVGVHLVHLKNARELVRTAATSSPEVSASAPEFAAQVDYVLGIHDGVAPGELFLSAGTQSGVVGIFPLVQGSPSMRGTSAYVGLGAPAAVLRRGHRDIVRSIVWDANATASESARVPATVGEDALVCAWTPDVGNEERPPVDRARPPGRRHSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTX4</accession>
    <name>A4RTX4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_92381</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ELP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416571.1">
        <property type="nucleotide sequence ID" value="XM_001416534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTX4"/>
    <dbReference type="STRING" id="436017.A4RTX4"/>
    <dbReference type="GeneID" id="5000600"/>
    <dbReference type="Gramene" id="ABO94864">
        <property type="protein sequence ID" value="ABO94864"/>
        <property type="gene ID" value="OSTLU_92381"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92381"/>
    <dbReference type="eggNOG" id="ENOG502QTQT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1176816_0_0_1"/>
    <dbReference type="OMA" id="HIYYERD"/>
    <dbReference type="OrthoDB" id="10492978at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019519">
        <property type="entry name" value="Elp5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15641">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15641:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="262" mass="28715" checksum="4C1F2E4F3313A473" modified="2007-05-15" version="1" fragment="single">VTTRDATRDATATTTGRGRRSGAFGYKPDAEANATVVLDCASKIRRAYGEKALIRVVRALRRHRNVCLVVTLGVGTATARETCEAEASCVATCEPAEGDDDGSRARLDVEIRRACGRRRRERERVIIRDDDSLEFAPCEAESVEDAVARALRVGDDDAETRAARRLQAVVPFNLGVSLTAEEREAKRNVKLSYEHQGVRGVEAYDTGDFLAYLPPDAGGRGVALGVAKPGRGHIYYERDAADEDLDDDDLHVDTDDELEEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTX8</accession>
    <name>A4RTX8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BEACH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_86630</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416862.1">
        <property type="nucleotide sequence ID" value="XM_001416825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTX8"/>
    <dbReference type="STRING" id="436017.A4RTX8"/>
    <dbReference type="GeneID" id="5001046"/>
    <dbReference type="Gramene" id="ABO95155">
        <property type="protein sequence ID" value="ABO95155"/>
        <property type="gene ID" value="OSTLU_86630"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86630"/>
    <dbReference type="eggNOG" id="KOG1786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_276522_0_0_1"/>
    <dbReference type="OMA" id="FVADEYP"/>
    <dbReference type="OrthoDB" id="29306at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46866">
        <property type="entry name" value="GH12955P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46866:SF1">
        <property type="entry name" value="GH12955P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH" evidence="4">
        <location>
            <begin position="148"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1018"/>
            <end position="1053"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1151" mass="124865" checksum="CA9497735742CF72" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTY4</accession>
    <name>A4RTY4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416865.1">
        <property type="nucleotide sequence ID" value="XM_001416828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTY4"/>
    <dbReference type="GeneID" id="5000932"/>
    <dbReference type="Gramene" id="ABO95158">
        <property type="protein sequence ID" value="ABO95158"/>
        <property type="gene ID" value="OSTLU_30429"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30429"/>
    <dbReference type="HOGENOM" id="CLU_1148574_0_0_1"/>
    <dbReference type="OMA" id="LMWAKCD"/>
    <dbReference type="OrthoDB" id="497596at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="241" mass="26713" checksum="861B0D830A767EA8" modified="2007-05-15" version="1">MRAATAPRPARALAPRKHAARRATVADAARSLADIERAWARSSYDLSLRWPLTNELCALEIARAELDPARFRVGWHKCKSYVGITYLYDDERDGGERGDVFLSKYVMLDPAFENVVGCVRHELAHAVAGVAGVDHGRAFKDACDALDVPEAWRKATTGAFYSRPSVQLMWAKCDAEEALRGRGRDVLPELLFERNVWDAPVNGNRTVFKDEESGVVLDAFEMYDLTVAEEARAANSSDVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU00</accession>
    <name>A4RU00_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_86646</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416874.1">
        <property type="nucleotide sequence ID" value="XM_001416837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU00"/>
    <dbReference type="STRING" id="436017.A4RU00"/>
    <dbReference type="GeneID" id="5000775"/>
    <dbReference type="Gramene" id="ABO95167">
        <property type="protein sequence ID" value="ABO95167"/>
        <property type="gene ID" value="OSTLU_86646"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86646"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="DVLLCQH"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000132">
        <property type="entry name" value="Serine/threonine-protein kinase SRK2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="321"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="38724" checksum="433D4C607B250C4A" modified="2007-05-15" version="1">MAHRALARELSDLYAPPDGPSSRARVLGCGNFGTAKLMRSKRTNELVAIKYIERGARIDENVKRELVNHRLLTHGNVVRFIEVVLTKTHLAIAMEYASGGELFDRILKKGKFCEAEARYFFQQLISGVAHCHAKGVAHRDLKLENTLLDGDAVPRLKICDFGYSKNAFIDSDPKSTVGTPAYIAPEVLERKPYDGKTADVWSCGVTLFVMLCGKYPFEDRRKPRDFRSTILKIRSCDYAIPPGVELSAGCLDLIQRIFVVDAAKRIDIAGIKAHPWFLIDLPIELVDDAIAANPTNASPTSTMSIEEILAIVEEAKTPYEGAERDHHDAQMDGDHDMVTSGEFDDDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU66</accession>
    <name>A4RU66_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_33904</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416619.1">
        <property type="nucleotide sequence ID" value="XM_001416582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU66"/>
    <dbReference type="STRING" id="436017.A4RU66"/>
    <dbReference type="GeneID" id="5001039"/>
    <dbReference type="Gramene" id="ABO94912">
        <property type="protein sequence ID" value="ABO94912"/>
        <property type="gene ID" value="OSTLU_33904"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33904"/>
    <dbReference type="eggNOG" id="ENOG502QRKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062543_0_0_1"/>
    <dbReference type="OMA" id="CLWKYNY"/>
    <dbReference type="OrthoDB" id="10248252at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="37978" checksum="F1CCE58709714848" modified="2007-05-15" version="1">MTYEILEYSTTSVDFTPHDSRWIPHSARFVVLGETAKSTGRLGVFKLSDSGVTSVCETERDSGLKCCTFGSHTLPERFIATGSLSGELETWDLEHASEPRSSFKAHRGAVNAIDGIGGGTHGIGALEIVTGGRDGTVKVWDTRQDSAVAIFKSVSASTCECWCVAFGNSFDENERCVLAGYENGDVKMFDLRVGTVRYETNIANGVCSVEFDRKDITMNKFVATCLESQFVVFDARTQHPDDGFASVTQNSSVKTTIWGVRHLPQDREVFATLLGDGSVALYRYEYPVKRQRLCPAGKPQGVAGSAKRISSTSLASQPINSWDWHAEKTGLAVCSGFDQHVRVVVMTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUB7</accession>
    <name>A4RUB7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_4067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416642.1">
        <property type="nucleotide sequence ID" value="XM_001416605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUB7"/>
    <dbReference type="GeneID" id="5000769"/>
    <dbReference type="Gramene" id="ABO94935">
        <property type="protein sequence ID" value="ABO94935"/>
        <property type="gene ID" value="OSTLU_4067"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4067"/>
    <dbReference type="eggNOG" id="ENOG502QPZW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038878_1_2_1"/>
    <dbReference type="OMA" id="VDFRNHY"/>
    <dbReference type="OrthoDB" id="25002at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF3">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="124"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="309" mass="35145" checksum="9045B12139C0B8C6" modified="2007-05-15" version="1" fragment="single">ATVDEDAPKYQLITFFRFAAIEDPVAEVERHRAHIERRGWELRGRIYVNEQGINAQMSGRGREGEEYAQWVESDARFAGMRISVYPMDAQAHPRLALRYKPNLVQLEGGTNHLPLTDREKRAKPNGYEWDVGHFRGAERPVQESFRETVYTNVQDGLGPLANVDKEKPIMMYCTGGIRCDVYSTVLREQGYKNVMTLEGGVQAYFDEYGKRDDQLWDNHLFVFDSRLAMAPDGRPSAELGEAAATLRCYCCGDSSAPPPHRNCPNVDCNRLFLVCSKCTDKLDGFCCEECTKSAHVRPQLVVPGRYEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUE5</accession>
    <name>A4RUE5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_86714</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416659.1">
        <property type="nucleotide sequence ID" value="XM_001416622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUE5"/>
    <dbReference type="STRING" id="436017.A4RUE5"/>
    <dbReference type="GeneID" id="5000788"/>
    <dbReference type="Gramene" id="ABO94952">
        <property type="protein sequence ID" value="ABO94952"/>
        <property type="gene ID" value="OSTLU_86714"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86714"/>
    <dbReference type="eggNOG" id="KOG2187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043022_0_0_1"/>
    <dbReference type="OMA" id="QCNTIFV"/>
    <dbReference type="OrthoDB" id="10250660at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030697">
        <property type="term" value="F:tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.1070:FF:000001">
        <property type="entry name" value="tRNA/tmRNA (uracil-C(5))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000012">
        <property type="entry name" value="tRNA/tmRNA (uracil-C(5))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01011">
        <property type="entry name" value="RNA_methyltr_TrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011869">
        <property type="entry name" value="TrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02143">
        <property type="entry name" value="trmA_only"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47790">
        <property type="entry name" value="TRNA/TMRNA (URACIL-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47790:SF2">
        <property type="entry name" value="TRNA_TMRNA (URACIL-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="418" mass="46812" checksum="D6DD53185B3E984D" modified="2007-05-15" version="1">MFRASVALGARRLSNGYLFACPRAAGARARRRYRPSGATCRLDVECRPSSYDEELREKTAHARAHFDGVATLPSRTETFESAREEFRMRAEFKVWHDGDRSYFAMCDSDRPKDPVEVVDFPMASARIRELMPELLREVTATETLRRKLFQANFLTTTTGDAVVSLLYHRQLDEDWEREAEAMRARLGIDVIGRARKQKLVLAKDFVTEKVLIDGKEFSYKQLEGSFTQPNAGIAAQMLAWARSAAVSDSPDVVAAATPRDANRDFLELYCGNGHFTIALAPLFRKCLATEISKSSVAAAHVNMAANGIDNVVTARLSAEELCDALDGGREYTRLKDIDLTTYDLSTVLVDPPRAGMGDEVSKFCARFDRIIYISCNPETLARDCKILGETHEIKRFAVFDQFPYTPHLESGALLVKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV76</accession>
    <name>A4RV76_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416794.1">
        <property type="nucleotide sequence ID" value="XM_001416757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV76"/>
    <dbReference type="GeneID" id="5001010"/>
    <dbReference type="Gramene" id="ABO95087">
        <property type="protein sequence ID" value="ABO95087"/>
        <property type="gene ID" value="OSTLU_30874"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30874"/>
    <dbReference type="eggNOG" id="ENOG502SC2K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1100025_0_0_1"/>
    <dbReference type="OMA" id="ARASKKW"/>
    <dbReference type="OrthoDB" id="515160at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="253" mass="25702" checksum="8C0AA1266D25327A" modified="2007-05-15" version="1">MSTTARATASASARRATPARARGATRTRAVRRRAIARRATGDGTTRADADADADADEAAAARASKKWKPKPLPSTFGDAASPRARSPFDAKTGATSPFEKAPGTSASPFEKATSDGTGKPASPFGAVATPVTEGGAASGDATTTRAKAAASPFGAAEARSPFAAAPGAAKSPFGGASAAKNPFNEPEAALYGAKPVAKKPAVKVEEKTSFLESLPRPTLGQFFIVFSFVTIISLMLGTFWVVVNAGGVHFNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVC6</accession>
    <name>A4RVC6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_14850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417397.1">
        <property type="nucleotide sequence ID" value="XM_001417360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVC6"/>
    <dbReference type="STRING" id="436017.A4RVC6"/>
    <dbReference type="GeneID" id="5001461"/>
    <dbReference type="Gramene" id="ABO95690">
        <property type="protein sequence ID" value="ABO95690"/>
        <property type="gene ID" value="OSTLU_14850"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14850"/>
    <dbReference type="eggNOG" id="KOG0154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_941325_0_0_1"/>
    <dbReference type="OMA" id="SACESDY"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16166">
        <property type="entry name" value="OCRE_SUA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041591">
        <property type="entry name" value="OCRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035623">
        <property type="entry name" value="SUA-like_OCRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948:SF3">
        <property type="entry name" value="FI21118P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17780">
        <property type="entry name" value="OCRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="37"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="32523" checksum="8EE1DDEE6232D9B7" modified="2007-05-15" version="1">MTRGRSACFQCFTQDEADKKYRTDEVDRAAADKHPTPVLFIRNIPSDATEEELAKKVSAIDKTLFVRSIQMPVERETGFRKGFAFVDCTSIEQARVVKDLLDGTAFREGDWTNGALSVEFSISKLSQKLATPVSAAAQVAILQATAASAMTTAASESDYTFDKATGYYRHKTTGILYDANTGLFFNAITNAWYSWNETTQEYTQVGSKSVVESPPKEETERRPVVATLSSAPKPEPSVLKEDVKVVMSYRDRAKERRKLHREGVALDRLVSGEPAASAVKGRVTGGKMRAGKRGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVE3</accession>
    <name>A4RVE3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MscS family transporter: small-conductance mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_30945</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417120.1">
        <property type="nucleotide sequence ID" value="XM_001417083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVE3"/>
    <dbReference type="STRING" id="436017.A4RVE3"/>
    <dbReference type="GeneID" id="5001199"/>
    <dbReference type="Gramene" id="ABO95413">
        <property type="protein sequence ID" value="ABO95413"/>
        <property type="gene ID" value="OSTLU_30945"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30945"/>
    <dbReference type="eggNOG" id="ENOG502S8B0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_577966_0_0_1"/>
    <dbReference type="OMA" id="GWHSTRI"/>
    <dbReference type="OrthoDB" id="431980at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049142">
        <property type="entry name" value="MS_channel_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566:SF5">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566">
        <property type="entry name" value="YNAI-RELATED MECHANOSENSITIVE ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21088">
        <property type="entry name" value="MS_channel_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="Mechanosensitive channel protein MscS (YggB), transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel transmembrane helices 2/3" evidence="9">
        <location>
            <begin position="266"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="8">
        <location>
            <begin position="309"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="473" mass="52257" checksum="9802A94720278F9B" modified="2007-05-15" version="1">MAKFSGSSSDFDEHDDDELVAGVLTKKATKNVMLLVALVAAVASVTYLVTMVSMNAERGLADVLYTLVFDDVWANIAITVLVLYTGAIKKAVEFALTTTATFVRPTRVNMLWWVSLFCLRSIKHVTNIIRNTFVWSLGNQIWSLIPLGIDLIKFDPETTADGVDHVHSLLTTMFDANNDGVVTTTEVQMWFVAKTLRLLWCFYFLDLSRWFMSLKAAPTIQEMRTRGSSYDREDFLSQALRHHYAGLRGDRGVSWDSQARSALIDKALTVATYLLTSYWCLSALGVNMTGLLAVGGVSGIAVGFAAQKLVSNCIGGILIFVTQPFVEGDHVQFGSIDGRVEMVGWHSTRIASIDDGYSYIVPNTDVLGSALKNISRREYVPIKLAIPFPDYVKSKTSMETYVADVKKIVFDKVDDWSVRSPVVNMEFDGLTPKIRIKAFIDGSKEKNKASDLEVQLMGAIVEKMQPSSSGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVE7</accession>
    <name>A4RVE7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417411.1">
        <property type="nucleotide sequence ID" value="XM_001417374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVE7"/>
    <dbReference type="GeneID" id="5001634"/>
    <dbReference type="Gramene" id="ABO95704">
        <property type="protein sequence ID" value="ABO95704"/>
        <property type="gene ID" value="OSTLU_30949"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30949"/>
    <dbReference type="HOGENOM" id="CLU_951200_0_0_1"/>
    <dbReference type="OrthoDB" id="10644341at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="293" mass="31599" checksum="C408520BBF1EBA07" modified="2007-05-15" version="1">MRRHAGSLQMEFVARAIAVADKTSAIVETWLDDRSDAVERLASTQARFQRECAALRLQLEKALAAARSAKRNGAEDAKEAVLRCVKGCEALRVGLLRDMRALSAHLTAEEAQLSRKFVTEWRALEDAGNEALRASIDFDKLIAQDATRIDATALLALVEDCTGCAAVGTIADPRALVEAYENECVLMCARRLHNFVAKPPPRGGEELSAVVKAMKLESQPSASPSTGEGSTTPAAPSTPAKRREEAAKTRESVALEFAAHLRGYFGARDDARAVLDDLEDACADFIAVGIAQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVQ9</accession>
    <name>A4RVQ9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417189.1">
        <property type="nucleotide sequence ID" value="XM_001417152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVQ9"/>
    <dbReference type="GeneID" id="5001448"/>
    <dbReference type="Gramene" id="ABO95482">
        <property type="protein sequence ID" value="ABO95482"/>
        <property type="gene ID" value="OSTLU_92580"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92580"/>
    <dbReference type="eggNOG" id="ENOG502S3KG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2030626_0_0_1"/>
    <dbReference type="OMA" id="GRIQGGM"/>
    <dbReference type="OrthoDB" id="421474at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47721">
        <property type="entry name" value="OS01G0235100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47721:SF2">
        <property type="entry name" value="OS01G0235100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="122" mass="12784" checksum="B8EF54AC1BAFBBD7" modified="2007-05-15" version="1">MRATTTTTTATTTTTTTTTRAKTRATTRATRRAHVARANASPDGDATKAACAGSCDSCGLAKEKMQCDGSGRIQGGMGAIPLFAWWPIKAYRPCPGLIDNGGVYTRKGQDVNAILWGESGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVT4</accession>
    <name>A4RVT4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_37135</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417206.1">
        <property type="nucleotide sequence ID" value="XM_001417169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVT4"/>
    <dbReference type="STRING" id="436017.A4RVT4"/>
    <dbReference type="GeneID" id="5001633"/>
    <dbReference type="Gramene" id="ABO95499">
        <property type="protein sequence ID" value="ABO95499"/>
        <property type="gene ID" value="OSTLU_37135"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37135"/>
    <dbReference type="eggNOG" id="KOG2509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_4_3_1"/>
    <dbReference type="OMA" id="EQNCIDR"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000055">
        <property type="entry name" value="Serine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="257"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="331"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="418"/>
            <end position="421"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="8">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="502" mass="55178" checksum="8176E90C0976AD07" modified="2007-05-15" version="1">MHRRVVAAAAARTRTTSSSSSSSPLAASVVARRWTPGRPAQRATLATRASATSEAPALNASGETNKALAWKAAIDFKFVRDNAELVQKNATTRKVDVDVQEIIAKYEALNALNFKCDELRERRNANAKSMKGKMDKEVRDGLIAEGKAIKDELAALEGDLAGLESELQTMAQRLPNLTHPDVPIGSEENTVTRATVGEQRAFTFPVQNHVDVGEKLGMFDFETGSKVSGSRFVYLTGVGAMLELALINWAFAKVLSKGFKPMMVPDMVRSSVVEKCGFQPRAENTQVYSIENSDLCMAGTAELLLGGVYMDEVVEESQLPIKMAAFSHCFRTEAGAAGAQTRGMYRLHQFSKVEMFVVATPEQSDALHEELIGIETEMFAELGFHFKVLDMPTEDLGAPAYRKFDVEAWMPALERYGEISSASNCTDYQARRLNIKYRPNAVDGKKQPLMHCHTLNATACAIPRMIVTILENFQQEDGSVVVPEPLRPYLGGMDVLRPEEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVV7</accession>
    <name>A4RVV7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417215.1">
        <property type="nucleotide sequence ID" value="XM_001417178.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RVV7"/>
    <dbReference type="GeneID" id="5001320"/>
    <dbReference type="Gramene" id="ABO95508">
        <property type="protein sequence ID" value="ABO95508"/>
        <property type="gene ID" value="OSTLU_31113"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31113"/>
    <dbReference type="eggNOG" id="ENOG502R346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_258098_0_0_1"/>
    <dbReference type="OMA" id="MCKKVAQ"/>
    <dbReference type="OrthoDB" id="128924at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="991"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="845"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1345" mass="143595" checksum="DF1822C726137E7B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVX6</accession>
    <name>A4RVX6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="3">1.3.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_31136</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="3"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417487.1">
        <property type="nucleotide sequence ID" value="XM_001417450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVX6"/>
    <dbReference type="STRING" id="436017.A4RVX6"/>
    <dbReference type="GeneID" id="5001179"/>
    <dbReference type="Gramene" id="ABO95780">
        <property type="protein sequence ID" value="ABO95780"/>
        <property type="gene ID" value="OSTLU_31136"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31136"/>
    <dbReference type="eggNOG" id="KOG2333">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_0_4_1"/>
    <dbReference type="OMA" id="YSGRANW"/>
    <dbReference type="OrthoDB" id="272303at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="13">
        <location>
            <begin position="49"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="371" mass="40264" checksum="06A10D1DF51A565A" modified="2007-05-15" version="1">MEGLGDARFRVALAANGAGGFDEACREFIRIPGALPNGADPTKLVKNLCANYDADELRFNATARVPLGAQIMGSEPWLLELAARHLATEKSAPRIDLNCGCPANVVTGKGAGSSLLRDPEYVYACVKAVADGARGSGAHVTMKLRSGYDDSSLLRENLLAAREAGARFVSLHARTRAQGYSGRANWEEIAFAKDVLDIPVLGNGDVTSPQRAAELLRVSDADGIMLGRGAVQDPLIFRRIAATVSRDAQGVVRVSDDVFEREFEVELVIDFLRTFAAEVFKTENKPNGKRGSGVQAQELETFKVGKIKSIVKYLFAGNPNLLPHMKSVMQLDPTKTSAEDVLRTVETLVRAEWQTPQNVLVDAFSKRNQYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWB9</accession>
    <name>A4RWB9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC(ABCG) family transporter: multidrug (ABCG)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_36892</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417300.1">
        <property type="nucleotide sequence ID" value="XM_001417263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWB9"/>
    <dbReference type="STRING" id="436017.A4RWB9"/>
    <dbReference type="GeneID" id="5001517"/>
    <dbReference type="Gramene" id="ABO95593">
        <property type="protein sequence ID" value="ABO95593"/>
        <property type="gene ID" value="OSTLU_36892"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36892"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_57_7_1"/>
    <dbReference type="OMA" id="QWYSRID"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF91">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="521"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="70"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="655" mass="71708" checksum="AE716E07841A6C06" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWM0</accession>
    <name>A4RWM0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_15185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417355.1">
        <property type="nucleotide sequence ID" value="XM_001417318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWM0"/>
    <dbReference type="STRING" id="436017.A4RWM0"/>
    <dbReference type="GeneID" id="5001250"/>
    <dbReference type="Gramene" id="ABO95648">
        <property type="protein sequence ID" value="ABO95648"/>
        <property type="gene ID" value="OSTLU_15185"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15185"/>
    <dbReference type="eggNOG" id="KOG4843">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049820_0_0_1"/>
    <dbReference type="OMA" id="KWINFEW"/>
    <dbReference type="OrthoDB" id="3596986at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013951">
        <property type="entry name" value="Rxt3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08642">
        <property type="entry name" value="Rxt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="35785" checksum="1E4C813FFC1AE7C6" modified="2007-05-15" version="1">MMRDGGLTIGRCFDAIVDDVTSVDYREGESLAAHLKLDEGVLDVCIPAEATSTANQHLRTRQLWGTDVYTADSDIVAVLTHTGYYRPSGVMPPNLGAVRAVIRATPHPEDGYPSTSRNGIRSRSWGHIKEGCGFVVESARAVTSSGVEIDLTPNTMRRKVSPTFFPIEKEHVVHTRNSAANATGKKGLIREVTIQYNLCNEPWMKYSVSLVADQGFKRSQWTCARLRREVLYVETHHKRYELSCVPGKDGEESRFRWAASKKPLPLDKTREVGVPLPKAHVDVAADDLRWDEIHWGSNSVIIRDKEYQLARLQYLPRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWQ7</accession>
    <name>A4RWQ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31421</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a role in mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of a tri-snRNP complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SNUT3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417622.1">
        <property type="nucleotide sequence ID" value="XM_001417585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWQ7"/>
    <dbReference type="STRING" id="436017.A4RWQ7"/>
    <dbReference type="GeneID" id="5001661"/>
    <dbReference type="Gramene" id="ABO95915">
        <property type="protein sequence ID" value="ABO95915"/>
        <property type="gene ID" value="OSTLU_31421"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31421"/>
    <dbReference type="eggNOG" id="KOG3263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075596_5_2_1"/>
    <dbReference type="OrthoDB" id="21368at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013957">
        <property type="entry name" value="SNRNP27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31077">
        <property type="entry name" value="U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31077:SF1">
        <property type="entry name" value="U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08648">
        <property type="entry name" value="SNRNP27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="61" mass="6874" checksum="15D9CA4F29E69441" modified="2007-05-15" version="1">MRMMGFGGFGTTQGKHVEDEFANASAVQKKTKRQARQYMNRVGGFNRPLPAEVTGQRQNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWS9</accession>
    <name>A4RWS9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ETFB lysine methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Protein N-lysine methyltransferase METTL20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_6437</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. ETFBKMT family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417384.1">
        <property type="nucleotide sequence ID" value="XM_001417347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWS9"/>
    <dbReference type="STRING" id="436017.A4RWS9"/>
    <dbReference type="GeneID" id="5001649"/>
    <dbReference type="Gramene" id="ABO95677">
        <property type="protein sequence ID" value="ABO95677"/>
        <property type="gene ID" value="OSTLU_6437"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6437"/>
    <dbReference type="eggNOG" id="ENOG502QQTZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049382_4_0_1"/>
    <dbReference type="OMA" id="WIVPEWT"/>
    <dbReference type="OrthoDB" id="419617at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050078">
        <property type="entry name" value="Ribosomal_L11_MeTrfase_PrmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00406">
        <property type="entry name" value="prmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43648">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43648:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="31324" checksum="BC48580023875CF6" modified="2007-05-15" version="1" fragment="single">GALGDVLLSLGASSVSTIDADAGTEDEHEIFSANTFEEQASDKTKARVWAKCHVTAYFEDHARARAGIEAAEEILGISLEASYAESKSNDWVQAVKDSFTPTKIADGLYIVPDWCKDVDANAVNIALEPGIAFGTGEHPTTRLCLRWLKQTLARRGKTELVVDFGCGSGVLAIGALVMGADRAVGVDLAKQAVQSSIDNAKLNGVEDRLTTYLGDGRDPGTPGANGQADVVVANILIGPVLELEPLFAGYCKVGGEIALSGILYGEQSASVVAKYARHFDNICVVEEGGWACVHGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXF7</accession>
    <name>A4RXF7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_38943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417992.1">
        <property type="nucleotide sequence ID" value="XM_001417955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXF7"/>
    <dbReference type="STRING" id="436017.A4RXF7"/>
    <dbReference type="GeneID" id="5001836"/>
    <dbReference type="Gramene" id="ABO96285">
        <property type="protein sequence ID" value="ABO96285"/>
        <property type="gene ID" value="OSTLU_38943"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38943"/>
    <dbReference type="eggNOG" id="KOG2938">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036838_2_1_1"/>
    <dbReference type="OMA" id="NVEHIHA"/>
    <dbReference type="OrthoDB" id="432381at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047622">
        <property type="term" value="F:adenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047724">
        <property type="term" value="F:inosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045437">
        <property type="term" value="F:uridine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072585">
        <property type="term" value="F:xanthosine nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006218">
        <property type="term" value="P:uridine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF4">
        <property type="entry name" value="URIDINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="5">
        <location>
            <begin position="35"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="396" mass="42493" checksum="2FB24FB290C6D7DB" modified="2007-05-15" version="1">MSSPATTHTNAPVDASSTRTASPASTPASPPPRKLIIDTDPGVDDAFAIALALETMSTEVEVLGLTTVFGNVRRDDATRNARTLVEMCALAGSWRREAGARLPVVDGARAPLAALDEDDRSGAGASTADDSAVLVADFVHGEDGFGGVRGAYETRPEESAVEHRAGREAADFIAEMCAKYPGEVTVLALAPLTNIALTFRRHPECSETMGELVVLGGAFEVNGNVNPAAEANILGDPEAADEVFGAFERTFVVGLDVTTRVRLSGAEIERLETVLRDADAVSPPRRCSNLLRAFLHDATQFYKAYHLRVADFDGIYVHDPTALLLALPHVRDAVFTFRRGAVRVALARDCARGAVFLDARRAWLFRNAWSDRPRVSVAMDVDVDAALRELRARLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXJ4</accession>
    <name>A4RXJ4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_92755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417764.1">
        <property type="nucleotide sequence ID" value="XM_001417727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXJ4"/>
    <dbReference type="GeneID" id="5001708"/>
    <dbReference type="KEGG" id="olu:OSTLU_92755"/>
    <dbReference type="eggNOG" id="KOG0691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1463594_0_0_1"/>
    <dbReference type="OrthoDB" id="442087at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12429">
        <property type="entry name" value="RRM_DNAJC17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034254">
        <property type="entry name" value="DNAJC17_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45098">
        <property type="entry name" value="DNAJ DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45098:SF1">
        <property type="entry name" value="DNAJ DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="38"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="19608" checksum="6F8BF4E44D8A1EBF" modified="2007-05-15" version="1" fragment="single">LRRRREEATRGGKARDGDGVGTAATTSTVPEHLYRALKVVWRRDGDADDDAYSAKELREIFETFGRIEDVVIREGKKKKGSALVVFADGDACATASGATCGRSSNPLVVARAAIPPKVDAGEPAKRRDDAASGGVSPAPASETTAARAPSVANLDFESVVLERLKRAQERARLVAEAEAEGDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXQ2</accession>
    <name>A4RXQ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_49552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418032.1">
        <property type="nucleotide sequence ID" value="XM_001417995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXQ2"/>
    <dbReference type="GeneID" id="5002110"/>
    <dbReference type="Gramene" id="ABO96325">
        <property type="protein sequence ID" value="ABO96325"/>
        <property type="gene ID" value="OSTLU_49552"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49552"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013173_1_5_1"/>
    <dbReference type="OMA" id="PMELNVE"/>
    <dbReference type="OrthoDB" id="497134at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF827">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="49"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="329" mass="35568" checksum="96673FCD1D6905ED" modified="2007-05-15" version="1">MGSESTSSGGARDLDSARASPPLSDEVSEAATATADGEANIPLVGAQVVVGVAFEQGQRAYMEDRYSAVTELKPFGLTGCDGVRRSFLGVYDGHNGDWAAQFASERMHTFLAPDVLLQDSSPSCPERLTRFNVDMETSLKKMYMDCDDEILNSTAAEGRRDGSTAVCVLQIGGALFTAHAGDSRAVVSYADGRTRAMTEDHKPSMSNERRRITAVGGKIEFCGCWRVIADHPYKPVRAALAVSRSLGDIDFKRPKDSGVTAEPDVSRYELTEDINFIILASDGMWDVIRDQEAGDIARKILATRGVLSEGNMHRGSSDNVTVVVAMYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYD1</accession>
    <name>A4RYD1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418366.1">
        <property type="nucleotide sequence ID" value="XM_001418329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYD1"/>
    <dbReference type="GeneID" id="5002395"/>
    <dbReference type="Gramene" id="ABO96659">
        <property type="protein sequence ID" value="ABO96659"/>
        <property type="gene ID" value="OSTLU_15648"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15648"/>
    <dbReference type="HOGENOM" id="CLU_1311967_0_0_1"/>
    <dbReference type="OrthoDB" id="10637975at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="210" mass="21668" checksum="BC2DDF0B3A5F98EA" modified="2007-05-15" version="1">MARDASTPTRAMDRAKGGVGEKRRAAAMMTTPTPRAADRGGGAGRGKETPESVVRAPMAGGDTLWSPVAVRASVGGGGGLESPERSGGTPTLGGESGDEETREATMAMPAATATMGDGAEGYTYGTPPSSPSARNSAPACPATPFKARRTRQIGADDSSAPRPRGRVVRSLLEEFDAAERGLEDMLGDTHSENTTLRTLDDGFDPFDDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYF3</accession>
    <name>A4RYF3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_3284</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418375.1">
        <property type="nucleotide sequence ID" value="XM_001418338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYF3"/>
    <dbReference type="STRING" id="436017.A4RYF3"/>
    <dbReference type="GeneID" id="5002258"/>
    <dbReference type="KEGG" id="olu:OSTLU_3284"/>
    <dbReference type="eggNOG" id="KOG2111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025895_2_1_1"/>
    <dbReference type="OMA" id="DCRIFTT"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="38189" checksum="F57D138C49D719EC" modified="2007-05-15" version="1" fragment="single">LSISYNQDGACFAVARRDGRARGFSVYNTSPYRETFGRKFRDGGVGIVEMLFRCNILALVGGGDEPKFSPNKVMIWDDHQGRCIGELGFKVPVRGVRLRRDKVVVALAHKIFVYNFSDLKMEQQIDTAANERGLCAISPTTERTVMACPGLNRGQVRVELFDLGTTKFIAAHETALACLGLSADGSLLATASEKGTLIRIFDTHTASLVHEFRRGSDRARVYSLAFSPKKNLLCVTSDKGTVHVFRIPETPSASSSAPTASPIPTPSSNGARTPSSSSPAAGFVKKLLPKYFSSEWSLAQFKLPSTARSLVTFPAADPDSCIIISERGEYSRLIFDLGGGGKMSLVERFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYH4</accession>
    <name>A4RYH4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418166.1">
        <property type="nucleotide sequence ID" value="XM_001418129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYH4"/>
    <dbReference type="GeneID" id="5002271"/>
    <dbReference type="Gramene" id="ABO96459">
        <property type="protein sequence ID" value="ABO96459"/>
        <property type="gene ID" value="OSTLU_24646"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24646"/>
    <dbReference type="HOGENOM" id="CLU_461839_0_0_1"/>
    <dbReference type="OrthoDB" id="500682at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="591" mass="65476" checksum="2A893CC511D88B73" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYH5</accession>
    <name>A4RYH5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EIF3F/CSN6-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418391.1">
        <property type="nucleotide sequence ID" value="XM_001418354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYH5"/>
    <dbReference type="STRING" id="436017.A4RYH5"/>
    <dbReference type="GeneID" id="5002264"/>
    <dbReference type="Gramene" id="ABO96684">
        <property type="protein sequence ID" value="ABO96684"/>
        <property type="gene ID" value="OSTLU_32030"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32030"/>
    <dbReference type="eggNOG" id="KOG3050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1039728_0_0_1"/>
    <dbReference type="OMA" id="WYERTSD"/>
    <dbReference type="OrthoDB" id="1378at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF8">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EIF3F/CSN6-like C-terminal" evidence="2">
        <location>
            <begin position="121"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="268" mass="29050" checksum="2D4C8ABDF6F963BD" modified="2007-05-15" version="1">MAVEGAAIAASDGTTRADAALALERDAAARRTRDDVRPLGWYRVVDDRDEANEEDLAIGDAFARDVMARATRDGDDGEAAAAAVFALVSARGGADDAPGVRWYERGSDGLREETFTVEMLEAERIVVDEVAKIAPEGRDSRSARFASSLESAATATTALRDRLAVVLEYLRAVKDGRAVLDRDVLREVAKAMVVLRTSSSEALREDFADEYENTLVLNYLTAMTKTTDGLSEAIDKFHIVHGDHSLVTATRFHTRGRGMPPTPGHDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYI8</accession>
    <name>A4RYI8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418171.1">
        <property type="nucleotide sequence ID" value="XM_001418134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYI8"/>
    <dbReference type="STRING" id="436017.A4RYI8"/>
    <dbReference type="GeneID" id="5002356"/>
    <dbReference type="Gramene" id="ABO96464">
        <property type="protein sequence ID" value="ABO96464"/>
        <property type="gene ID" value="OSTLU_32043"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32043"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013267_0_0_1"/>
    <dbReference type="OMA" id="LIMYEEA"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053303">
        <property type="entry name" value="Chloroplast_PPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47935">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN MRL1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47935:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN MRL1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="3">
        <location>
            <begin position="197"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="293"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="433"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="468"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="889" mass="99848" checksum="10BC9C7F6178CEC1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ84</accession>
    <name>A4RZ84_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SF4 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418285.1">
        <property type="nucleotide sequence ID" value="XM_001418248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ84"/>
    <dbReference type="STRING" id="436017.A4RZ84"/>
    <dbReference type="GeneID" id="5002420"/>
    <dbReference type="Gramene" id="ABO96578">
        <property type="protein sequence ID" value="ABO96578"/>
        <property type="gene ID" value="OSTLU_94562"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94562"/>
    <dbReference type="eggNOG" id="ENOG502QPXS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020382_1_0_1"/>
    <dbReference type="OMA" id="EGCKDAN"/>
    <dbReference type="OrthoDB" id="1898560at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027032">
        <property type="entry name" value="Twinkle-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873">
        <property type="entry name" value="T7-LIKE MITOCHONDRIAL DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873:SF0">
        <property type="entry name" value="TWINKLE MTDNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56731">
        <property type="entry name" value="DNA primase core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="2">
        <location>
            <begin position="329"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="592" mass="66216" checksum="852D1378D06C692A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZI2</accession>
    <name>A4RZI2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS family transporter: sugar</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_41151</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418575.1">
        <property type="nucleotide sequence ID" value="XM_001418538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZI2"/>
    <dbReference type="GeneID" id="5002284"/>
    <dbReference type="Gramene" id="ABO96868">
        <property type="protein sequence ID" value="ABO96868"/>
        <property type="gene ID" value="OSTLU_41151"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41151"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OMA" id="WTIWVAM"/>
    <dbReference type="OrthoDB" id="1396207at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17315">
        <property type="entry name" value="MFS_GLUT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
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        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
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        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF12">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="45044" checksum="DD1244D328E6CB6A" modified="2007-05-15" version="1">MLSVGCACGAIAGALVYIESGTVLGTLTTTMKGAVVAALPLGAMFGCAATPGLNEPFGRRFALGCCDVGFIVSAALMASASAVEQVVLGRFVAGLAVGIATSMCTMYISECAPAKTRGKHSGLAPLSVTVGLLGSFVLSLFATNVVDGWRYMFAFAAVPALVQLGIILKTNALPESPRWLAENCRVGEAKAVFNSLGQPDVDVHVIALNATTKPTSKILSLFKDAKTRNALGVASLMNFFQQACGINVVIYYAPKILSDLGFDRSHAIALTACVSVVQIIAGTWLSRSIDAIGRRPLALGGIGAISFALALLTLSVTPSVYLHFMSATAAPWLAVAAILVFRIAFSVSLGPVPYIVTSEVFPQKVRNVGVSAATAVQWIMNALVTFTFLRIREIWSAQGVWMLYFTVSVFALTVVYKVLPETTGKTLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZM9</accession>
    <name>A4RZM9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cleavage/polyadenylation specificity factor A subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_50104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418790.1"/>
    </dbReference>
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    <dbReference type="Gramene" id="ABO97120">
        <property type="protein sequence ID" value="ABO97120"/>
        <property type="gene ID" value="OSTLU_50104"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50104"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002414_0_0_1"/>
    <dbReference type="OMA" id="PMTKFKL"/>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:nucleic acid binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
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        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="15"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="524"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="1015"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="397"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1386" mass="149324" checksum="5023D716984E6E85" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZS0</accession>
    <name>A4RZS0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ribosomal protein S27a, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RPS27a</name>
        <name evidence="12" type="ORF">OSTLU_32483</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the 40S subunit of the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Part of the 40S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418619.1">
        <property type="nucleotide sequence ID" value="XM_001418582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZS0"/>
    <dbReference type="STRING" id="436017.A4RZS0"/>
    <dbReference type="GeneID" id="5002673"/>
    <dbReference type="Gramene" id="ABO96912">
        <property type="protein sequence ID" value="ABO96912"/>
        <property type="gene ID" value="OSTLU_32483"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32483"/>
    <dbReference type="eggNOG" id="KOG0004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010412_2_0_1"/>
    <dbReference type="OMA" id="HANRHYC"/>
    <dbReference type="OrthoDB" id="1649877at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000008">
        <property type="entry name" value="Ubiquitin-40S ribosomal protein S27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_eS31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038582">
        <property type="entry name" value="Ribosomal_eS31_euk-type_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01402">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="11">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00035123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="150" mass="16965" checksum="CA5EBDB8860D2BF3" modified="2007-05-15" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGGKKRKKKTYTKPKKVKHVHKKVKLATLKLYKVDDAGKVERLRKECISPTCGAGVFVAQMFDRVYCGKCCQSWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0F0</accession>
    <name>A4S0F0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ABCB) family transporter: multidrug (P-glycoprotein-like protein) (ABCB)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_49993</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418734.1">
        <property type="nucleotide sequence ID" value="XM_001418697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0F0"/>
    <dbReference type="STRING" id="436017.A4S0F0"/>
    <dbReference type="GeneID" id="5002902"/>
    <dbReference type="Gramene" id="ABO97027">
        <property type="protein sequence ID" value="ABO97027"/>
        <property type="gene ID" value="OSTLU_49993"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49993"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_1"/>
    <dbReference type="OMA" id="HDRWASG"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="1"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="306"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="521" mass="56678" checksum="DDB6FCE88731BC08" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S103</accession>
    <name>A4S103_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Complex III subunit VI</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Mitochondrial hinge protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_32929</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419278.1">
        <property type="nucleotide sequence ID" value="XM_001419241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S103"/>
    <dbReference type="STRING" id="436017.A4S103"/>
    <dbReference type="GeneID" id="5003306"/>
    <dbReference type="Gramene" id="ABO97571">
        <property type="protein sequence ID" value="ABO97571"/>
        <property type="gene ID" value="OSTLU_32929"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32929"/>
    <dbReference type="eggNOG" id="KOG4763">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115913_2_1_1"/>
    <dbReference type="OrthoDB" id="405848at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.20:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="12">
        <location>
            <begin position="2"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00076110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="52" mass="6029" checksum="DD6D08CC08BFBA66" modified="2007-05-15" version="1">MPKCEKFVKLYEACAERIKGDETGEAHCTGQYFDMYKCVDECAKDEVMRRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S194</accession>
    <name>A4S194_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal RNA-processing protein 8</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_33018</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probable methyltransferase required to silence rDNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
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    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="5003415"/>
    <dbReference type="Gramene" id="ABO97403">
        <property type="protein sequence ID" value="ABO97403"/>
        <property type="gene ID" value="OSTLU_33018"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33018"/>
    <dbReference type="eggNOG" id="KOG3045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027694_1_2_1"/>
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        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:rRNA processing"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2150:FF:000001">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
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    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
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    </dbReference>
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    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="226" mass="24757" checksum="E6618A522E82E555" modified="2007-05-15" version="1">MNKMRAKLSGGQFRMLNERLYTTTGDEGLALVKDSPELFEAYHAGFRSQVESWPTKPVDVIAGALKKSPKSWVVADFGCGDAELGRVIEQKCHSFDLQTPECAPEVIACNMSDVPLGDASVDCAVFSLSLMGTDYGSFLEEAHRVLKPGGLLWIAEVRSRFDGKNGAATVSSFVAALGALGFRLGRDPDERNTMFFTVELLKTFATPRASAPIRWPPLKACSYKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1C3</accession>
    <name>A4S1C3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419124.1">
        <property type="nucleotide sequence ID" value="XM_001419087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1C3"/>
    <dbReference type="GeneID" id="5003087"/>
    <dbReference type="Gramene" id="ABO97417">
        <property type="protein sequence ID" value="ABO97417"/>
        <property type="gene ID" value="OSTLU_16435"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16435"/>
    <dbReference type="HOGENOM" id="CLU_415869_0_0_1"/>
    <dbReference type="OrthoDB" id="10659134at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="660" mass="72451" checksum="0878240C11E9815B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1N4</accession>
    <name>A4S1N4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_42846</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419396.1">
        <property type="nucleotide sequence ID" value="XM_001419359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1N4"/>
    <dbReference type="STRING" id="436017.A4S1N4"/>
    <dbReference type="GeneID" id="5003179"/>
    <dbReference type="Gramene" id="ABO97689">
        <property type="protein sequence ID" value="ABO97689"/>
        <property type="gene ID" value="OSTLU_42846"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42846"/>
    <dbReference type="eggNOG" id="KOG0147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020551_5_1_1"/>
    <dbReference type="OMA" id="WERRHSS"/>
    <dbReference type="OrthoDB" id="8123449at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
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        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="135"/>
            <end position="212"/>
        </location>
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    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="245"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="422"/>
            <end position="505"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="516" mass="56937" checksum="F8E0007A6951DDB5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2A0</accession>
    <name>A4S2A0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoribosylaminoimidazole carboxylase</fullName>
            <ecNumber evidence="4">4.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">AIR carboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_33376</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2</text>
            <dbReference type="Rhea" id="RHEA:10792"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.21" evidence="4"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419714.1">
        <property type="nucleotide sequence ID" value="XM_001419677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2A0"/>
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    <dbReference type="GeneID" id="5003586"/>
    <dbReference type="Gramene" id="ABO98007">
        <property type="protein sequence ID" value="ABO98007"/>
        <property type="gene ID" value="OSTLU_33376"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33376"/>
    <dbReference type="eggNOG" id="KOG2835">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_011534_2_1_1"/>
    <dbReference type="OMA" id="PANVKWK"/>
    <dbReference type="OrthoDB" id="15425at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000013">
        <property type="entry name" value="Phosphoribosylaminoimidazole carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000037">
        <property type="entry name" value="Phosphoribosylaminoimidazole carboxylase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016301">
        <property type="entry name" value="Ade2_fungi/plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054350">
        <property type="entry name" value="PurT/PurK_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004679">
        <property type="entry name" value="PRK06019.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609:SF5">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609">
        <property type="entry name" value="PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22660">
        <property type="entry name" value="RS_preATP-grasp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001340">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52255">
        <property type="entry name" value="N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="90"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO98007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="542" mass="56878" checksum="29C666B002F750F1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2D6</accession>
    <name>A4S2D6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_34965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2D6"/>
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    <dbReference type="GeneID" id="5003735"/>
    <dbReference type="Gramene" id="ABO97804">
        <property type="protein sequence ID" value="ABO97804"/>
        <property type="gene ID" value="OSTLU_34965"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34965"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_012062_15_7_1"/>
    <dbReference type="OMA" id="HMKSAGD"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
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        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
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        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="14"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="114"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="21585" checksum="95F3CD7E1860502A" modified="2007-05-15" version="1">MTSRVGNPAVNADTKVYVGNLPYGCSWQDLKDHFSNAMGGESVRFADILTSRDGRSKGCGIVTFNSSEDAKKAIETMHDTEIGERKIFVREDREGERGNDLRNRIGPSATSPDASVYVGNLPWSTRWQELKDIFRKVGNVAHADVTMGFDGRSRGWGVVTFMDPQCAQVAIERLNGTMLNDRALIVRRDERARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2L4</accession>
    <name>A4S2L4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419551.1">
        <property type="nucleotide sequence ID" value="XM_001419514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2L4"/>
    <dbReference type="GeneID" id="5003607"/>
    <dbReference type="Gramene" id="ABO97844">
        <property type="protein sequence ID" value="ABO97844"/>
        <property type="gene ID" value="OSTLU_16768"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16768"/>
    <dbReference type="HOGENOM" id="CLU_537930_0_0_1"/>
    <dbReference type="OMA" id="PFHVVFK"/>
    <dbReference type="OrthoDB" id="10627830at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="507" mass="56907" checksum="292275A3BCD60739" modified="2007-05-15" version="1">MRVPARDGIKRVIIIAFFFAASAVEFGTYPVASVVEFRVQAPRFPTSSHRKSFLSARARERATATASATRFGEAFGYSWTVEARTRETDGRNEVEVRAARTRGLGLTSTRMFAFTVVTRTGVSAQSMRDRLVGTSGRELPTSAHIEQSLVESTLSTAELTKIPGASGEHGDVDLVIRVRLWSNPFHVVFKDEVYDVATILGLTTYASVLILRGLSELRDERERRRAARKVRLMRSEIAQLESVANEKADKLRILSAIARVPFVAVFETVQIPMRVVDWTASAISDILIETANLVLIVILLLMPPSRENAPMASSENHAKQATGSKHNRKHRQRPPRSPKRRSELDPKSEHARKESMDILLKRFVIAEEDMDEERQRAAKDAIGHAQAQMRAKMKRDRITDMRLRDSKQREGEDFAAELFANVPGLSVGTRDMRPMSSSSSDTHERQASWELHNRQKSLIHHMLQEIDGLELPPDSKTTVPIEEPVTPKSSHTKNPSFARVWNAPTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2X2</accession>
    <name>A4S2X2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419611.1">
        <property type="nucleotide sequence ID" value="XM_001419574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2X2"/>
    <dbReference type="GeneID" id="5003822"/>
    <dbReference type="Gramene" id="ABO97904">
        <property type="protein sequence ID" value="ABO97904"/>
        <property type="gene ID" value="OSTLU_33599"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33599"/>
    <dbReference type="HOGENOM" id="CLU_1055210_0_0_1"/>
    <dbReference type="OrthoDB" id="498728at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="264" mass="28336" checksum="4A1BE62C15959E00" modified="2007-05-15" version="1">MTTAKARRRASDPAGAVRRIFDERRARRAAATIRTTTTTNAGRRTSEPTPARARFARALDGALDDALDDAEASGGASARDGDDDASDGAYGLLLRAARDERAARDASLPEEYSLQEVRDGGAACEDLVALSVAFEREDARVGSLAGGLGGAVAHVLRTASGEAVGYTLTYENRAPEWDRARAVVLPPRLAHVFIRRDHRMRGLGTGLVNWWRRRFALRCAFFAVDSPNDSMTRTLLRVECAPATTRSGHGASSVHYIAPVAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Z6</accession>
    <name>A4S2Z6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419831.1">
        <property type="nucleotide sequence ID" value="XM_001419794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Z6"/>
    <dbReference type="STRING" id="436017.A4S2Z6"/>
    <dbReference type="GeneID" id="5003891"/>
    <dbReference type="Gramene" id="ABO98124">
        <property type="protein sequence ID" value="ABO98124"/>
        <property type="gene ID" value="OSTLU_93278"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93278"/>
    <dbReference type="eggNOG" id="ENOG502R8TF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1091508_0_0_1"/>
    <dbReference type="OMA" id="HFYLSEG"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012223">
        <property type="entry name" value="TEII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11487:SF0">
        <property type="entry name" value="S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="255" mass="28585" checksum="C0FD8DF9575D9349" modified="2007-05-15" version="1">MADLVTCQPAKQNMDRVLVCFPPAGATASCFNGDFTRAVDARCFAVDKPCRWRRCVPEVETLRWSVVDFARDVARRIVEHGCVSKGESLYLYGHSAGAWIAFECARALGERVSGVYVSAARAPCLGHWLNDTDVETPRLSELETDDAFWAAFERRYGVSDELRCVSTSLIAPFREDFRMSESYEGSTEKVHVPLTAIGIENDTRTTREMIARWSEHTTGAFCSRWWDGGGAHPHRALIAKPLEFASFLSNEVFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S310</accession>
    <name>A4S310_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CASP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_33636</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419837.1">
        <property type="nucleotide sequence ID" value="XM_001419800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S310"/>
    <dbReference type="STRING" id="436017.A4S310"/>
    <dbReference type="GeneID" id="5003839"/>
    <dbReference type="Gramene" id="ABO98130">
        <property type="protein sequence ID" value="ABO98130"/>
        <property type="gene ID" value="OSTLU_33636"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33636"/>
    <dbReference type="eggNOG" id="KOG0963">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_424176_0_0_1"/>
    <dbReference type="OMA" id="KNARYSC"/>
    <dbReference type="OrthoDB" id="498992at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012955">
        <property type="entry name" value="CASP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043">
        <property type="entry name" value="CCAAT DISPLACEMENT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043:SF2">
        <property type="entry name" value="HOMEOBOX PROTEIN CUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08172">
        <property type="entry name" value="CASP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="627"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="CASP C-terminal" evidence="5">
        <location>
            <begin position="340"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="80"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="435"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="646" mass="70357" checksum="239B6087E99C75CC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S396</accession>
    <name>A4S396_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_38141</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419879.1">
        <property type="nucleotide sequence ID" value="XM_001419842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S396"/>
    <dbReference type="STRING" id="436017.A4S396"/>
    <dbReference type="GeneID" id="5004228"/>
    <dbReference type="Gramene" id="ABO98172">
        <property type="protein sequence ID" value="ABO98172"/>
        <property type="gene ID" value="OSTLU_38141"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38141"/>
    <dbReference type="eggNOG" id="KOG2667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034705_1_0_1"/>
    <dbReference type="OMA" id="GPTHGMY"/>
    <dbReference type="OrthoDB" id="270930at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="5"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="179"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="373" mass="41256" checksum="27EB6E0F799B8C41" modified="2007-05-15" version="1">MTNILKALDANPKLKEDYVSESTSGVITTLVCAALCLILFFGEFFSYKTTKIVSELRVNPLGVHQTVPNAERLKIDVDITFHSLACNLITLDTSDKAGEEHYDVHDGHIEKRRIDKHGKVIDAAFTSEKPNKHKEIEQALQKMNETDSAHAADSHAMEHVQPFGGMFGLQSLLQEVFPEGVEHAFRNENQEGCEVKGYLEVNRVPGRFSISPGRSLMMGMQMVKLNVQTALNLTHTIHRLSFGESFPGLVSPLDGTHRSLPPNAVQQYFLNVVSTTFEPLGENKIISTHQYSVTETFTSSQRSIMGTSNGRDPGVIFTYEISPIRVDFKETRTSFGAFVLGICSVIGGVVTMAGITQNAVEYIISNRKTLFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3I7</accession>
    <name>A4S3I7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitrate reductase [NADH]</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_3554</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419925.1">
        <property type="nucleotide sequence ID" value="XM_001419888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3I7"/>
    <dbReference type="STRING" id="436017.A4S3I7"/>
    <dbReference type="GeneID" id="5004057"/>
    <dbReference type="Gramene" id="ABO98218">
        <property type="protein sequence ID" value="ABO98218"/>
        <property type="gene ID" value="OSTLU_3554"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3554"/>
    <dbReference type="eggNOG" id="KOG0535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_5_4_1"/>
    <dbReference type="OMA" id="YDERYAI"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043436">
        <property type="term" value="P:oxoacid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000003">
        <property type="entry name" value="Nitrate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022407">
        <property type="entry name" value="OxRdtase_Mopterin_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00559">
        <property type="entry name" value="MOLYBDOPTERIN_EUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase molybdopterin-binding" evidence="8">
        <location>
            <begin position="53"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Moybdenum cofactor oxidoreductase dimerisation" evidence="9">
        <location>
            <begin position="267"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="375" mass="42352" checksum="E920C62B9D5C2E23" modified="2007-05-15" version="1" fragment="single">DERDLKTPDNWVKRHPNLIRLTGKHPFNVEASLPELYDYGFISPVNLHIVRNHGAVPKCDWDTHKINICGNVPKPFEIGMDELVKMPSDTFPCLVVCAGNRRKEQNLVKSSIGFSWGPCAIGNTYWTGVPLRVLLNRAGIHKPGPGARYVCLAGPQNELPKDYPDQDGGPGSYGTSIDMETALDPTCDVIVAYEQNGAKLHPDHGFPVRVIIPGYIGGRMIKFLKEIKVTDRESNNFYHFNDNRVLPPPVDAERATEEGWWFKPEFIINQLNINGAIAYPAPEEVIPKSQKTYAFKGYAYSGGGRKVIRAELSFDQGLSWELSDIHTREEPRWADFSSGDKARHWCWCMWTLEVPIEKLLDKKCVEVCFRAVDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3J9</accession>
    <name>A4S3J9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidoglycan binding-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419931.1">
        <property type="nucleotide sequence ID" value="XM_001419894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3J9"/>
    <dbReference type="GeneID" id="5004063"/>
    <dbReference type="Gramene" id="ABO98224">
        <property type="protein sequence ID" value="ABO98224"/>
        <property type="gene ID" value="OSTLU_26080"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26080"/>
    <dbReference type="HOGENOM" id="CLU_872621_0_0_1"/>
    <dbReference type="OMA" id="ARWANIR"/>
    <dbReference type="OrthoDB" id="10660586at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="entry name" value="PGBD-like superfamily/PGBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="PGBD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="34927" checksum="47EF56510645A160" modified="2007-05-15" version="1">MSARLTREFGMGDSGTDVSLAQRLLGRDARRAHGVCDRETTEALRAWQISRGLKPSGFFGASSRAQMAMEEERWRELGGGALLERLWEEEARARDASERANERAGGSGRTRGVVATSTTPREAPRVSRVARGALVLVVASAALGAAARLRNRERFAAFVDSATAWTRESRAKVALDVAREFIGACGARARARWTEIAADFAERRRALVRAAATAISRVRSAAERVATNDALDAGAPLAEGHFDENGRWWESPLPASTPKAADARPRPAEPSPRGGASTARERAEQMRERWVNIRRQQVDVGADERRAIERVSKFLRDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3R4</accession>
    <name>A4S3R4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_3117</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419965.1">
        <property type="nucleotide sequence ID" value="XM_001419928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3R4"/>
    <dbReference type="STRING" id="436017.A4S3R4"/>
    <dbReference type="GeneID" id="5004149"/>
    <dbReference type="KEGG" id="olu:OSTLU_3117"/>
    <dbReference type="eggNOG" id="KOG0376">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004962_0_5_1"/>
    <dbReference type="OrthoDB" id="497745at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="5">
        <location>
            <begin position="110"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="31363" checksum="1E869CFFE2FD5D61" modified="2007-05-15" version="1" fragment="single">LEDIIDSLKRGNVFSLIDAMAILQAATVRFAEEESVNYVNAEPGGSVVVVGDLHGQLHDLLFVLKERGMPSDKVKYVFNGDLVDRGNHGCEIALLLCALKLASPRCVFINRGNHEEAFINIYSGFEEECLQKYDHKVFQMFQSCFDWLPYACVVNESVFVIHGGPPCDEGATVDEVRTLPRGAESARVSVDKRRVGWYKELVWSDPHPEATFIGSVPSHRGAGVLWGKDVSERFLQKNKLEVIIRSHQCVAGGVETCHGGKVFTLFSASRYCGTGENKGAILSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S471</accession>
    <name>A4S471_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Adenosine kinase</fullName>
            <shortName evidence="11">AK</shortName>
            <ecNumber evidence="4 11">2.7.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Adenosine 5'-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_50659</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine + ATP = AMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20824"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.20" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420220.1">
        <property type="nucleotide sequence ID" value="XM_001420183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S471"/>
    <dbReference type="STRING" id="436017.A4S471"/>
    <dbReference type="GeneID" id="5004191"/>
    <dbReference type="Gramene" id="ABO98513">
        <property type="protein sequence ID" value="ABO98513"/>
        <property type="gene ID" value="OSTLU_50659"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50659"/>
    <dbReference type="eggNOG" id="KOG2854">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045832_0_0_1"/>
    <dbReference type="OMA" id="YCATECI"/>
    <dbReference type="OrthoDB" id="432447at2759"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004001">
        <property type="term" value="F:adenosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01168">
        <property type="entry name" value="adenosine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000006">
        <property type="entry name" value="Adenosine kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001805">
        <property type="entry name" value="Adenokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769:SF3">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00989">
        <property type="entry name" value="ADENOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 11" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="12">
        <location>
            <begin position="29"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO98513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="347" mass="37250" checksum="DEE7E9FCA350E285" modified="2007-05-15" version="1">MAPHANLRLLGMGNPLLDISVACEDDALLKKYDLKLNDAILAEAKHAPLYEEMATHGDVEYIAGGATQNTIRVAQWMMQREGATAYMGCVGEDKFATQMRASCENDGVLANYMVDASTPTGTCAVIVKDGERSLCAALNAANNYKAEHLDASENFALVERADFYYMAGFFMTVSPESIMRVAKHACENKKTFMMNLSAPFLMQVPPFLATLMEALPYVNILFGNESEAVTFAESQSWDTKDIKEIALKISAMPVAEGKPSRTVVITQGCDPTVVARDGAVEEYAVIPLAKEDLVDTNGAGDAFVGGYISQLVQGADVAKCCAAGNYAANKIIQESGCKCPGVPSFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4D3</accession>
    <name>A4S4D3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420248.1">
        <property type="nucleotide sequence ID" value="XM_001420211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4D3"/>
    <dbReference type="GeneID" id="5004445"/>
    <dbReference type="Gramene" id="ABO98541">
        <property type="protein sequence ID" value="ABO98541"/>
        <property type="gene ID" value="OSTLU_17236"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17236"/>
    <dbReference type="HOGENOM" id="CLU_053422_0_0_1"/>
    <dbReference type="OMA" id="YEARHLC"/>
    <dbReference type="OrthoDB" id="1892356at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47868">
        <property type="entry name" value="OS05G0457700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47868:SF2">
        <property type="entry name" value="OS05G0457700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="45033" checksum="B78E33773AF6A227" modified="2007-05-15" version="1">METALEDAKSMIEYARARWRVGARGDARGVLEHASVALRRRGEEPATSSAIARARTAWAHLARERGERGTARDAARDARDAARESGAPEDGASADAMWTLLEAREEAKEATWADVVEGARRGAGGGAGGRCAAAGAETLAALTRRRARDALEAAETCEIALRGMSSEELREAKDAPHGWAIASAMKALGHVERLTPSGSSERALELYERAAEYAKDVALSEHPGAMASRMIAEDLQADCALARAQAYAALGDVENAETFAARAVSAAEALGDEKHPRVGAAIAVSGDVYVAKALRSMSNDEKTSLGDGAGVMFAEGLYKSAIKLMHYPHVVEDGKIVLDYEARHLCALLHARYSSILRASGGQREREANAWLESAKILWPDERGDDEGVDGVDIVTKAATKLGVKHGPSVLIDLQQMAPLTMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4F7</accession>
    <name>A4S4F7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptidase M50 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_2307</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420429.1">
        <property type="nucleotide sequence ID" value="XM_001420392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4F7"/>
    <dbReference type="STRING" id="436017.A4S4F7"/>
    <dbReference type="GeneID" id="5004459"/>
    <dbReference type="Gramene" id="ABO98722">
        <property type="protein sequence ID" value="ABO98722"/>
        <property type="gene ID" value="OSTLU_2307"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2307"/>
    <dbReference type="eggNOG" id="ENOG502QUAP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028221_1_0_1"/>
    <dbReference type="OMA" id="NAIDPPD"/>
    <dbReference type="OrthoDB" id="195057at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009959">
        <property type="term" value="P:negative gravitropism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048564">
        <property type="term" value="P:photosystem I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060359">
        <property type="term" value="P:response to ammonium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043157">
        <property type="term" value="P:response to cation stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009723">
        <property type="term" value="P:response to ethylene"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009416">
        <property type="term" value="P:response to light stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd06160">
        <property type="entry name" value="S2P-M50_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044838">
        <property type="entry name" value="EGY1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412">
        <property type="entry name" value="ZINC METALLOPROTEASE EGY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412:SF0">
        <property type="entry name" value="ZINC METALLOPROTEASE EGY1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="404"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M50" evidence="14">
        <location>
            <begin position="195"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="420" mass="44362" checksum="9E7F9F0BA53CB522" modified="2007-05-15" version="1" fragment="single">KLVNILESPEEAAIAPKDVERIKKEIFGMQTFYVTAVENLGAEMNGAGVLFKGNLRTERAKVWETVQADLERMFNGEYTAFMLEEPPGEDGPSGDVAIDSKYGPRVSFLIVPSDRAGPSPGTAGWQYLLALALMGLTVGSAVQLGLVAEVSKLPPETMSWLQQAGDVELPEGALPPGLENFDSVAYVESALPVTIGVMAASVGHEVGHQIAAFMRKIKIGIPFLIPNSQLGTFGTLTQIKSTPETRADLFDVAAAGPVAGGMVALNLFVYGLTLSMGGDSPDLIPIPNALFNSSLLLGGISQLFLHAGAKGVMVHPYFIAGWCALTTQALNLLPVGSIDGGRMTQTAFGRRVLGATSLGTYIGLSFGIIASSLALPWAIYIVLTQRTPEFAPKDDVTEVDDGRATLAFALIAVAFLVLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4K8</accession>
    <name>A4S4K8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="12">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_3295</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="12"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420454.1">
        <property type="nucleotide sequence ID" value="XM_001420417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4K8"/>
    <dbReference type="STRING" id="436017.A4S4K8"/>
    <dbReference type="GeneID" id="5004352"/>
    <dbReference type="Gramene" id="ABO98747">
        <property type="protein sequence ID" value="ABO98747"/>
        <property type="gene ID" value="OSTLU_3295"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3295"/>
    <dbReference type="eggNOG" id="KOG2735">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037661_1_1_1"/>
    <dbReference type="OMA" id="LPNFWEC"/>
    <dbReference type="OrthoDB" id="10265393at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106245">
        <property type="term" value="F:L-serine-phosphatidylethanolamine phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006659">
        <property type="term" value="P:phosphatidylserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004277">
        <property type="entry name" value="PSS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF7">
        <property type="entry name" value="PHOSPHATIDYLSERINE SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03034">
        <property type="entry name" value="PSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671872" description="CDP-diacylglycerol--serine O-phosphatidyltransferase" evidence="13">
        <location>
            <begin position="26"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO98747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="366" mass="40933" checksum="A4476AB86CBE65A4" modified="2007-05-15" version="1" fragment="single">ARSPHTLTMLACGAVALAVATHAFANDANDARWTTEDGIRRGATGALGAYLAYGALQGPATHMTRPHAAVWKVVHAAFTMYLLALIVLLFQTPADAQKMLKFFWDDLGTPLPTRSYGGDCRVYTPGHRSGSFGIVYETLFDEFTVAHVLGWFGKAVAIRDWGLLWAYSIAFELCELTFEHWQPNFNECWWDMWVWDVMICNLLGICAGMWLVKFMRGKFHDWSGKKASSRSAAAKEPPRSPVRGALKTVLTSLTPASVDHYTWRPTGSPSRFLKCAFLVFCGLVFDLNLFFMKFVLHVPPSHNFCLYRLGLWFAMSNIAIREYYVFIETPDVGEAKLGPNAWLALAVLIVEFLVVVKNGRGKFTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4X1</accession>
    <name>A4S4X1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_88641</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420508.1">
        <property type="nucleotide sequence ID" value="XM_001420471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4X1"/>
    <dbReference type="STRING" id="436017.A4S4X1"/>
    <dbReference type="GeneID" id="5004522"/>
    <dbReference type="Gramene" id="ABO98801">
        <property type="protein sequence ID" value="ABO98801"/>
        <property type="gene ID" value="OSTLU_88641"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88641"/>
    <dbReference type="eggNOG" id="ENOG502QQWZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042585_1_0_1"/>
    <dbReference type="OMA" id="CHNEDST"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021883">
        <property type="entry name" value="LPA1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35498">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35498:SF4">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11998">
        <property type="entry name" value="DUF3493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="395" mass="43036" checksum="F5A99588437003A9" modified="2007-05-15" version="1" fragment="single">VRTATRTRASDESSSTTTRASYADAATAVNEGLRLFERGEHEAATRAFTRALEMKPNEDEARAASYNRACGYVKMNMYDEAKDDLIAAVNVHNLKFKVLTSDPDLDAFRASTQYGEVAAAVKGGRGASTMVNLRAEAQEPFRFFKLYLFGGLAAGAGLGLFIIGTRLIKAVQGGEGAPDLTETVTNLGINTVGLLAFSVLLRGELQGREKIIQKVEREEELGRLGVTLGDGDKNVLFSRLRGSYRVFIVAGSEEHITKTLESLERFKEKLTKNKIVILPVAMDESGEESGDELPFGQRRRKAKTSKTTELTASAAAALLGGDKKLKLMPVDNGAWKRWIINQIESSGFDPTVRDVFFGVAKNGTIWKSGAGIPNWMKLFEDLPDEDSIQGKVTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5C6</accession>
    <name>A4S5C6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_17513</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420750.1">
        <property type="nucleotide sequence ID" value="XM_001420713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5C6"/>
    <dbReference type="STRING" id="436017.A4S5C6"/>
    <dbReference type="GeneID" id="5004849"/>
    <dbReference type="Gramene" id="ABO99043">
        <property type="protein sequence ID" value="ABO99043"/>
        <property type="gene ID" value="OSTLU_17513"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17513"/>
    <dbReference type="eggNOG" id="KOG0666">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_6_1"/>
    <dbReference type="OMA" id="MVKSATW"/>
    <dbReference type="OrthoDB" id="6284126at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019900">
        <property type="term" value="F:kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000785">
        <property type="entry name" value="CMGC/CDK/CDK8 protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="4"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="359"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO99043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="383" mass="43735" checksum="7C45E8CD7893EF7A" modified="2007-05-15" version="1">MDDGEIVGQIGEGAFGRVMYARTTAGRVYAIKTFKTPPVRRDAKTGAIARDQVVGLPTPTFREVTTLRAMKHENIVHLHRVIVNKEERSLSLAIDYAEYDLGVILTWHRRHRRLVSRRMVKSATWQLLHGLHYLHSNWIMHRDIKPQNVLVMGDGSECGVVKIADFGLARFVDPGTLLKPLHENGPVVTLWYRAPELLLGARHYTRAVDIWAAGCIFAELCTLVVPFKGVPKGKEDPRTMYQEEQIEAIVRCKGTPSEETWPLLREHPYYERAKKFFYPPEHPEGVPADESSPMRSDPELAAVFDELCAYDPERRPTAFEALTAMDYFAKTEPEPTRNIFDYELAAGEHRIVYPHRKITHEGDKPPDDEAKPARHDAKRAKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5M5</accession>
    <name>A4S5M5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MC family transporter: succinate/fumarate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_88774</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420635.1">
        <property type="nucleotide sequence ID" value="XM_001420598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5M5"/>
    <dbReference type="GeneID" id="5004664"/>
    <dbReference type="Gramene" id="ABO98928">
        <property type="protein sequence ID" value="ABO98928"/>
        <property type="gene ID" value="OSTLU_88774"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88774"/>
    <dbReference type="eggNOG" id="KOG0766">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_0_3_1"/>
    <dbReference type="OMA" id="WGIYEEL"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904983">
        <property type="term" value="P:glycine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181:SF3">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="127"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="226"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="34316" checksum="857634430DBF4CA7" modified="2007-05-15" version="1">MGRDARGQAAKTAPGEPRSARASAEKKKNPAASFIGGASAGLVSSALLQPFEVVKTKMQAEKLRGARGMVNVAADVVKTNGMKGLWSGVSASCVRTTAGAGLYFFLLERVTRELAASFNKEKATPFERSAMTFGAGCSARMVAAVLLNPITVVKTRMEYAGANAGVRQGMVATFASVARKEGAGGLFSGLGSTVARDAPFSGLNLLLFTQTRHLMHEVARMQNREAGAADTFIAGALAGAGATFLTHPPDVIRTRVQLGRIMTQQSGSKMPAVSLAKILREEGVRALWVGSLPRVTRRTFQQAITWSMFDFVSRALGGTDIFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6B5</accession>
    <name>A4S6B5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420914.1">
        <property type="nucleotide sequence ID" value="XM_001420877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6B5"/>
    <dbReference type="STRING" id="436017.A4S6B5"/>
    <dbReference type="GeneID" id="5005023"/>
    <dbReference type="Gramene" id="ABO99207">
        <property type="protein sequence ID" value="ABO99207"/>
        <property type="gene ID" value="OSTLU_582"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_582"/>
    <dbReference type="eggNOG" id="KOG2102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002333_5_1_1"/>
    <dbReference type="OMA" id="MLLANMY"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="1">
        <location>
            <begin position="113"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="538" mass="60367" checksum="0D5D88466A038276" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6F4</accession>
    <name>A4S6F4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prefoldin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27097</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421083.1">
        <property type="nucleotide sequence ID" value="XM_001421046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6F4"/>
    <dbReference type="STRING" id="436017.A4S6F4"/>
    <dbReference type="GeneID" id="5005041"/>
    <dbReference type="Gramene" id="ABO99376">
        <property type="protein sequence ID" value="ABO99376"/>
        <property type="gene ID" value="OSTLU_27097"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27097"/>
    <dbReference type="eggNOG" id="KOG1760">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130032_1_0_1"/>
    <dbReference type="OMA" id="KFGRAIN"/>
    <dbReference type="OrthoDB" id="10250441at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="project" value="EnsemblPlants"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="F:unfolded protein binding"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0009631">
        <property type="term" value="P:cold acclimation"/>
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        <property type="project" value="EnsemblPlants"/>
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    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:response to salt stress"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PFD_beta-like"/>
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        <property type="entry name" value="PFDN4"/>
    </dbReference>
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        <property type="entry name" value="Prefoldin"/>
    </dbReference>
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        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Prefoldin_subunit_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="13889" checksum="05505842CC4A1348" modified="2007-05-15" version="1">MSAAKEVTWEDQQRICAFSRMNARAHEINSEIKHKEKQIDDLDEASTELAVNDEDDACVLMGECFVKMDNEQAEAKVEAMLTRERAALEALKGERKVLREGMEELKKKLYERLGNSINLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6J1</accession>
    <name>A4S6J1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27138</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421102.1">
        <property type="nucleotide sequence ID" value="XM_001421065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6J1"/>
    <dbReference type="STRING" id="436017.A4S6J1"/>
    <dbReference type="GeneID" id="5005159"/>
    <dbReference type="Gramene" id="ABO99395">
        <property type="protein sequence ID" value="ABO99395"/>
        <property type="gene ID" value="OSTLU_27138"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27138"/>
    <dbReference type="eggNOG" id="KOG1334">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012381_5_2_1"/>
    <dbReference type="OMA" id="TELFICC"/>
    <dbReference type="OrthoDB" id="4869960at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="DCAF8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
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        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="468"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="482"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="547" mass="60250" checksum="335BD1DAB28D8704" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6N6</accession>
    <name>A4S6N6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA/rRNA methyltransferase SpoU type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_5165</name>
        <name evidence="9" type="ORF">OSTLU_5166</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420979.1">
        <property type="nucleotide sequence ID" value="XM_001420942.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422915.1">
        <property type="nucleotide sequence ID" value="XM_001422878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6N6"/>
    <dbReference type="STRING" id="436017.A4S6N6"/>
    <dbReference type="GeneID" id="5004977"/>
    <dbReference type="GeneID" id="5006892"/>
    <dbReference type="Gramene" id="ABO99272">
        <property type="protein sequence ID" value="ABO99272"/>
        <property type="gene ID" value="OSTLU_5165"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01274">
        <property type="protein sequence ID" value="ABP01274"/>
        <property type="gene ID" value="OSTLU_5166"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5165"/>
    <dbReference type="KEGG" id="olu:OSTLU_5166"/>
    <dbReference type="eggNOG" id="KOG0838">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_4_1_1"/>
    <dbReference type="OMA" id="KIPMVGF"/>
    <dbReference type="OrthoDB" id="241340at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002938">
        <property type="term" value="P:tRNA guanine ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18092">
        <property type="entry name" value="SpoU-like_TrmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033671">
        <property type="entry name" value="TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43453">
        <property type="entry name" value="RRNA METHYLASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43453:SF1">
        <property type="entry name" value="TRNA_RRNA METHYLTRANSFERASE SPOU TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="7">
        <location>
            <begin position="49"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="216" mass="23746" checksum="B727E046F66579D8" modified="2007-05-15" version="1" fragment="single">FPYGDGFAFARATCETETMVALATAMVGEERRMRLENVLEHRSFSLLPILEGVYDVGNILAVCRTTEALGIGCASIVSSKGLSFKASGRTSGGALKWQHVEQFETSERALRVAKAKGYRVLTTEFDGAQPLSHYDWTVPTAVVFGNEREGVSDEARALRDGAVYIPMFGFTESLNISVAAALVMSHAVTDRINRRGFHGDLTEEEKRILRGVYMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6S7</accession>
    <name>A4S6S7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Membrane alanyl aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_19807</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421145.1">
        <property type="nucleotide sequence ID" value="XM_001421108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6S7"/>
    <dbReference type="STRING" id="436017.A4S6S7"/>
    <dbReference type="MEROPS" id="M01.005"/>
    <dbReference type="GeneID" id="5005001"/>
    <dbReference type="Gramene" id="ABO99438">
        <property type="protein sequence ID" value="ABO99438"/>
        <property type="gene ID" value="OSTLU_19807"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19807"/>
    <dbReference type="eggNOG" id="KOG1046">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007993_2_0_1"/>
    <dbReference type="OMA" id="MDRINPR"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09600">
        <property type="entry name" value="M1_APN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000005">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1840:FF:000001">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000002">
        <property type="entry name" value="Putative aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.10">
        <property type="entry name" value="Peptidase M1, alanyl aminopeptidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038438">
        <property type="entry name" value="PepN_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012779">
        <property type="entry name" value="Peptidase_M1_pepN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024601">
        <property type="entry name" value="Peptidase_M1_pepN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037144">
        <property type="entry name" value="Peptidase_M1_pepN_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035414">
        <property type="entry name" value="Peptidase_M1_pepN_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02414">
        <property type="entry name" value="pepN_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322:SF1">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11940">
        <property type="entry name" value="DUF3458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17432">
        <property type="entry name" value="DUF3458_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="12">
        <location>
            <begin position="58"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="9">
        <location>
            <begin position="236"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="9">
        <location>
            <begin position="379"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 alanyl aminopeptidase Ig-like fold" evidence="10">
        <location>
            <begin position="439"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 alanyl aminopeptidase C-terminal" evidence="11">
        <location>
            <begin position="546"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="869" mass="95332" checksum="17B78861FB7025FB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="112" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6U9</accession>
    <name>A4S6U9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">cGMP-dependent protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_27248</name>
        <name evidence="12" type="ORF">OSTLU_29662</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421006.1">
        <property type="nucleotide sequence ID" value="XM_001420969.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422889.1">
        <property type="nucleotide sequence ID" value="XM_001422852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6U9"/>
    <dbReference type="STRING" id="436017.A4S6U9"/>
    <dbReference type="GeneID" id="5004928"/>
    <dbReference type="GeneID" id="5006857"/>
    <dbReference type="Gramene" id="ABO99299">
        <property type="protein sequence ID" value="ABO99299"/>
        <property type="gene ID" value="OSTLU_27248"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01248">
        <property type="protein sequence ID" value="ABP01248"/>
        <property type="gene ID" value="OSTLU_29662"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27248"/>
    <dbReference type="KEGG" id="olu:OSTLU_29662"/>
    <dbReference type="eggNOG" id="KOG0614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_73_2_1"/>
    <dbReference type="OMA" id="ESCLADC"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd05572">
        <property type="entry name" value="STKc_cGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035014">
        <property type="entry name" value="STKc_cGK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF139">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0140">cGMP</keyword>
    <keyword evidence="7" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="25"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="147"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="327"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP01248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="680" mass="76869" checksum="DDD13C121A792A3B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Y9</accession>
    <name>A4S6Y9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfurtransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_13229</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421178.1">
        <property type="nucleotide sequence ID" value="XM_001421141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6Y9"/>
    <dbReference type="STRING" id="436017.A4S6Y9"/>
    <dbReference type="GeneID" id="5005546"/>
    <dbReference type="Gramene" id="ABO99471">
        <property type="protein sequence ID" value="ABO99471"/>
        <property type="gene ID" value="OSTLU_13229"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13229"/>
    <dbReference type="eggNOG" id="KOG1529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031618_3_0_1"/>
    <dbReference type="OMA" id="NNNWFAS"/>
    <dbReference type="OrthoDB" id="270167at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01448">
        <property type="entry name" value="TST_Repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01449">
        <property type="entry name" value="TST_Repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000001">
        <property type="entry name" value="Sulfurtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364:SF27">
        <property type="entry name" value="SULFURTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="THIOSULFATE SULFERTANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00683">
        <property type="entry name" value="RHODANESE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="25"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="183"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="304" mass="32711" checksum="C6BA293F0ADDF670" modified="2007-05-15" version="1">MGAHASSASASASSALVSADWLDAHRDDVQIVDASWHMPDLKRNGAREHARTRLTPQTVFFDVDKVSDGRNPAPHMLPSAKAFEAACETLKLTKTKPIVVYDTNGMFSAARAWWMFRAHGWENVKVLDGGKPAWDARAYASDDAERAEEDIAAHVDACARAMRALGTRAELVKTKREVVENIQTKSFQVVDARGAARFRGETKEPREGVRSGHIPGSKNVFFGELLNEDKTFKPVEALRQVFETSGLDLSASAKPIVASCGTGVTAAIVALGLHECGVEAAVYDGSWTEYGADAQCPLATGPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S734</accession>
    <name>A4S734_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</fullName>
            <ecNumber evidence="12">7.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_43184</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.2" evidence="12"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421384.1">
        <property type="nucleotide sequence ID" value="XM_001421347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S734"/>
    <dbReference type="STRING" id="436017.A4S734"/>
    <dbReference type="GeneID" id="5005533"/>
    <dbReference type="Gramene" id="ABO99677">
        <property type="protein sequence ID" value="ABO99677"/>
        <property type="gene ID" value="OSTLU_43184"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43184"/>
    <dbReference type="eggNOG" id="KOG2658">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014881_0_1_1"/>
    <dbReference type="OMA" id="QGDGKPH"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.230:FF:000001">
        <property type="entry name" value="Mitochondrial NADH dehydrogenase flavoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.600:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11540:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054765">
        <property type="entry name" value="SLBB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010120">
        <property type="entry name" value="PRK13596.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22461">
        <property type="entry name" value="SLBB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="Nqo1 FMN-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142984">
        <property type="entry name" value="Nqo1 middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 12" id="KW-0288">FMN</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="13">
        <location>
            <begin position="350"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO99677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="449" mass="49157" checksum="436C6D7F6B3B4E06" modified="2007-05-15" version="1" fragment="single">PPPPPPPPPPRRLAERAHGDLKDQDRIFTNLYGKHDPFLKGAMKRGDWHNTKSLVELGADWIISEMKASGLRGRGGAGFPSGLKWSFMPRVSDGRPNYLVVNADESEPGTCKDREIMRHDPHKLLEGCLIAGTAMRARAAYIYIRGEYVNERLALERALAECYAAGYLGKNACGSGMDFDVNIHYGAGAYICGEETALIESLEGKQGKPRLKPPFPANVGLYGCPTTVTNVETVAVAPTILRRGADWFASFGRKNNAGTKLFCISGHVNNPCTVEEEMSIPLRDLIEKHCGGVRGGWDNLLAVIPGGSSVPLIPKNVCEDVLMDFDSLKEAQSGLGTAAVIVMDKSTDVIDAIARLSYFYKHESCGQCTPCREGTSWLYNIMQRMVKGDARLEEIDTLQELTKQIEGHTICALGDAAAWPIQGVIRHFRPLLEERISQFSSSPSEKITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S789</accession>
    <name>A4S789_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_25489</name>
        <name evidence="6" type="ORF">OSTLU_27463</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421414.1">
        <property type="nucleotide sequence ID" value="XM_001421377.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421444.1">
        <property type="nucleotide sequence ID" value="XM_001421407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S789"/>
    <dbReference type="GeneID" id="5005347"/>
    <dbReference type="GeneID" id="5005571"/>
    <dbReference type="Gramene" id="ABO99707">
        <property type="protein sequence ID" value="ABO99707"/>
        <property type="gene ID" value="OSTLU_25489"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99737">
        <property type="protein sequence ID" value="ABO99737"/>
        <property type="gene ID" value="OSTLU_27463"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25489"/>
    <dbReference type="KEGG" id="olu:OSTLU_27463"/>
    <dbReference type="eggNOG" id="KOG0648">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054299_1_0_1"/>
    <dbReference type="OMA" id="NNNTAIW"/>
    <dbReference type="OrthoDB" id="447842at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04670">
        <property type="entry name" value="NUDIX_ASFGF2_Nudt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003293">
        <property type="entry name" value="Nudix_hydrolase6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040618">
        <property type="entry name" value="Pre-Nudix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13994:SF13">
        <property type="entry name" value="FI03680P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13994">
        <property type="entry name" value="NUDIX HYDROLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18290">
        <property type="entry name" value="Nudix_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01356">
        <property type="entry name" value="GFGPROTEIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="104"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="274" mass="30130" checksum="00244C76B804709E" modified="2007-05-15" version="1">MATATNAPWTIDRYGGIIVDNAHDAFVRAARTPEAFDATLGGWLATWRASGARGVWLKLALDDARLVPVAKERGFEFHHAERTYVMMTTWLPSDEASTIPNNASHQVGVGAFVYDGENEKVLLVQERRGPASGRDLWKMPTGLLEAGEDIPDAAVREVLEETGIETTFDAVVGCRHGHFGLFGKSDLFFCVGLRVKDGASREIKIQETEIERAKWASVDEFLNNPNIEPGSHAHALHERCVRWSVGDYAGIVGKKLPLGFGRSGDVYTYVTTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7A1</accession>
    <name>A4S7A1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">POLQ-like helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_27406</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421235.1">
        <property type="nucleotide sequence ID" value="XM_001421198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7A1"/>
    <dbReference type="STRING" id="436017.A4S7A1"/>
    <dbReference type="GeneID" id="5005502"/>
    <dbReference type="Gramene" id="ABO99528">
        <property type="protein sequence ID" value="ABO99528"/>
        <property type="gene ID" value="OSTLU_27406"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27406"/>
    <dbReference type="eggNOG" id="KOG0950">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_768129_0_0_1"/>
    <dbReference type="OrthoDB" id="2320933at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048960">
        <property type="entry name" value="POLQ-like_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF6">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21099">
        <property type="entry name" value="POLQ_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLQ-like helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="361" mass="39945" checksum="59B6D0194BD86544" modified="2007-05-15" version="1">MPVTPEQRRFYLESIACGVLKTKEDAGELACRTFAWTSGRDNASILARQSRALKEIYEKGLVVARSGAHCAEWCSTPEGFAFYKCTLPIAHAKTLRKELSFALTNGLNLSTKTHLLFFCVSNETNVFAANLNWHAWSDWMSRYDSIHELGEKHLNVTRQYAERAQHRQGISDQAKATRSRHERLAAALLLSDVLASDDTTVDIARKWSTLSNNPVNRGMIQSLQNSAATTAGMASVLCEQCGWHALAGLLQNVSEELQAGARRELLPLMRLEGMTGARARALHNAGLTTPAKIAALQSDKFDKLQDACLRSLTRSRNGGLDQAMRTTAWRIASALVQSAREATIEEAKRALEDDSNAEWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7C6</accession>
    <name>A4S7C6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18067</name>
        <name evidence="3" type="ORF">OSTLU_18121</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421250.1">
        <property type="nucleotide sequence ID" value="XM_001421213.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421286.1">
        <property type="nucleotide sequence ID" value="XM_001421249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7C6"/>
    <dbReference type="GeneID" id="5005332"/>
    <dbReference type="GeneID" id="5005363"/>
    <dbReference type="Gramene" id="ABO99543">
        <property type="protein sequence ID" value="ABO99543"/>
        <property type="gene ID" value="OSTLU_18067"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99579">
        <property type="protein sequence ID" value="ABO99579"/>
        <property type="gene ID" value="OSTLU_18121"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18067"/>
    <dbReference type="KEGG" id="olu:OSTLU_18121"/>
    <dbReference type="HOGENOM" id="CLU_827396_0_0_1"/>
    <dbReference type="OMA" id="DEWNERT"/>
    <dbReference type="OrthoDB" id="503224at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="35681" checksum="4A8208B0C33B09E5" modified="2007-05-15" version="1">MANPFATLDGDARGDDGRDDGESGDAARGARAATAATRARRTTTTTTRAAKKRETAARRAEAEAMRARAHAAMAMEKREDDRWGKVAKGSGIARKAAKEMAKTMTTTAARDDDDATGETTTETTETTETTTTTSDAMAKVSEVFWHTFEDTGASCWCVRVEDEDGESTTMSITKSVPRARKIPSDGGERPVLVSGEIRLLLAEWDDRTRIDRARRAKAKLKAAKAAAKAAAEAAEAPAEAPAEAPAVETSPAPVAETLSAAPPDFGATRRAPPPGFEKPAFRVVHVPVVDPAVEARQRELEAQVAALQAQLAAQQMMQQTTYAPPPPSFSGGSSIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7J7</accession>
    <name>A4S7J7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421464.1">
        <property type="nucleotide sequence ID" value="XM_001421427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7J7"/>
    <dbReference type="GeneID" id="5005333"/>
    <dbReference type="Gramene" id="ABO99757">
        <property type="protein sequence ID" value="ABO99757"/>
        <property type="gene ID" value="OSTLU_27514"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27514"/>
    <dbReference type="HOGENOM" id="CLU_2744567_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="71" mass="8597" checksum="393F0C149A9114ED" modified="2007-05-15" version="1">MMRHTCPYHLISVTIKLVNLVKLRLGNARERRVDFSLVERRRRRRRRRTTTRVMLESRHSSIEDSVFSGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7V3</accession>
    <name>A4S7V3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CYN18-1</name>
        <name evidence="7" type="ORF">OSTLU_18195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421517.1">
        <property type="nucleotide sequence ID" value="XM_001421480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7V3"/>
    <dbReference type="STRING" id="436017.A4S7V3"/>
    <dbReference type="GeneID" id="5005424"/>
    <dbReference type="Gramene" id="ABO99810">
        <property type="protein sequence ID" value="ABO99810"/>
        <property type="gene ID" value="OSTLU_18195"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18195"/>
    <dbReference type="eggNOG" id="KOG0884">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_1"/>
    <dbReference type="OMA" id="VPFHRVM"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01928">
        <property type="entry name" value="Cyclophilin_PPIL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000012">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF2">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="10"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="17610" checksum="28248F38C074A74F" modified="2007-05-15" version="1">MSATLHTTCGDVKVELHVADCPRACENFLALCASGYYDQCAFHRCVKNFMIQSGDPTGTGRGGTSIYDGRAFKDEIRAHLRFSRRGMLAMANAGPNTNQSQFFLSFAKLPHLDGKVTIFGRVIDGHGTLDALERLAVDERDRPVRDAKIERVTIHANPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Y0</accession>
    <name>A4S7Y0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_8975</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MBF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421355.1">
        <property type="nucleotide sequence ID" value="XM_001421318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Y0"/>
    <dbReference type="STRING" id="436017.A4S7Y0"/>
    <dbReference type="GeneID" id="5005247"/>
    <dbReference type="Gramene" id="ABO99648">
        <property type="protein sequence ID" value="ABO99648"/>
        <property type="gene ID" value="OSTLU_8975"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8975"/>
    <dbReference type="eggNOG" id="KOG3398">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112609_0_2_1"/>
    <dbReference type="OMA" id="MLDERIP"/>
    <dbReference type="OrthoDB" id="495525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009414">
        <property type="term" value="P:response to water deprivation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.40:FF:000018">
        <property type="entry name" value="Multiprotein bridging factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245:SF15">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="34"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="88" mass="9712" checksum="2550D75864FDD5A4" modified="2007-05-15" version="1" fragment="single">RVVDSGAGRNALKLELDDENLTHKTVSADVKKAILQGRLAKKLTQAQLAQQINEKPQIVQEYESGKAIPNQQILGKLERILGVKLRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S871</accession>
    <name>A4S871_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cilia- and flagella-associated protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_27746</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CFAP45 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421711.1">
        <property type="nucleotide sequence ID" value="XM_001421674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S871"/>
    <dbReference type="STRING" id="436017.A4S871"/>
    <dbReference type="GeneID" id="5005614"/>
    <dbReference type="Gramene" id="ABP00005">
        <property type="protein sequence ID" value="ABP00005"/>
        <property type="gene ID" value="OSTLU_27746"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27746"/>
    <dbReference type="eggNOG" id="ENOG502QPRZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1020806_0_0_1"/>
    <dbReference type="OMA" id="AMRENCL"/>
    <dbReference type="OrthoDB" id="1902038at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033253">
        <property type="entry name" value="CFAP45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043597">
        <property type="entry name" value="TPH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15504:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15504">
        <property type="entry name" value="NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13868">
        <property type="entry name" value="TPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trichohyalin-plectin-homology" evidence="9">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="188"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="32858" checksum="23DFCC66EB1D7E18" modified="2007-05-15" version="1">MEQERRERESRKRVEDIERAFEEDAADKQRKRVAALKLLDEINAENEEQIKRKAEAERAERAEDERVMEYLRLKAERDAAKAAEEEAQRRARELETARLRSMQEKYIDGRAEQDFIRAQKLQDEYDRQTREKERAERAKRRQMLEDLAAARVAQHEEKVRLQRIEKENEKENAERLKREYEAQLLAERQREEARREAAAAHKRDLIHQMQSNEEAKRRAEARAAEEAEEARRRERQTHVLLEQIRERKVKEMERDAIPDKYTVELRSKKSVCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8H7</accession>
    <name>A4S8H7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">ER membrane protein complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_18371</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421622.1">
        <property type="nucleotide sequence ID" value="XM_001421585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8H7"/>
    <dbReference type="STRING" id="436017.A4S8H7"/>
    <dbReference type="GeneID" id="5005708"/>
    <dbReference type="Gramene" id="ABO99915">
        <property type="protein sequence ID" value="ABO99915"/>
        <property type="gene ID" value="OSTLU_18371"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18371"/>
    <dbReference type="eggNOG" id="KOG3188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060791_1_0_1"/>
    <dbReference type="OMA" id="KDMDPRW"/>
    <dbReference type="OrthoDB" id="6745403at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008568">
        <property type="entry name" value="EMC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116:SF5">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010045">
        <property type="entry name" value="DUF850_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="260" mass="28380" checksum="B87130C85AA00D97" modified="2007-05-15" version="1">MDASVVRLDAAIRAWVLLPITLAMFLVGALRHHAMRLTRDGGAADVVALREANVARRAERCRQFAGYLRPGAFAARRTFYCAADGGALRKKSEKASPHAAMLSDPTVMTKMMTKNAMMMAPNMLTAAWVNFFFAGFVVGRTPFPLTQRFRGMLQRGVALQSLDVTYVSSLSWYFLNFFGLGGVFQLVLGDNELDDAAAMQNAFASGLNADKAFAHALEGLEALKHEYMMHIADARATAMLRALNEGKSPREARLAAAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Q9</accession>
    <name>A4S8Q9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_40637</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421803.1">
        <property type="nucleotide sequence ID" value="XM_001421766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Q9"/>
    <dbReference type="STRING" id="436017.A4S8Q9"/>
    <dbReference type="GeneID" id="5005782"/>
    <dbReference type="Gramene" id="ABP00097">
        <property type="protein sequence ID" value="ABP00097"/>
        <property type="gene ID" value="OSTLU_40637"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40637"/>
    <dbReference type="eggNOG" id="ENOG502QQ8U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003927_1_1_1"/>
    <dbReference type="OMA" id="HRHTKHC"/>
    <dbReference type="OrthoDB" id="544240at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Rieske" evidence="10">
        <location>
            <begin position="48"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP00097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="510" mass="55051" checksum="7E5EDA5DB62BBBE1" modified="2007-05-15" version="1">MDKRTTRSATVRRHRSAVRLEATSEAATAETNAPPAAAGESFDWSSAWYPLRPVSFLDANEPNELRVLGKKLVAYLDPTCKEWRVLEDSCPHRRAPLSLGYVQKDGTLACRYHGWAFDGKDGSCVSIPMSVDEAAEKTACASPRSCATSYPSRVEDGILWVWPTAGADGLLASAGAPCATSLAREGTLPGEWGMVELPVGYAPALENQFDPSHAEWLHARYDAEGQLDERANAGFVAMTEFSVREGTMQKDGFVVEHGGYNKSNVGVSASRVFTAPCSSRSEYLDAKGKKYLSAAILYAPTEPGRTLMFTKFQAHQASAVQGAGARKLVRVGLSHGTPPGSSAYNLGDQDILAMHGVEVEMELQNKPWKQSYYLPTPADAGVSAFRNWMDKHAGGKVAWAPGVVDDASKVKSEAEQLDRYHRHTKHCVACKTALSELGVLEERCVAASKYLLAGGLFLAVTGAAFDQEAPAIIATCLAGASLVGAEKVRDMQHEFLSSVPRRGVPKPKLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8R6</accession>
    <name>A4S8R6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421674.1">
        <property type="nucleotide sequence ID" value="XM_001421637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8R6"/>
    <dbReference type="GeneID" id="5005812"/>
    <dbReference type="Gramene" id="ABO99967">
        <property type="protein sequence ID" value="ABO99967"/>
        <property type="gene ID" value="OSTLU_18435"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18435"/>
    <dbReference type="HOGENOM" id="CLU_704740_0_0_1"/>
    <dbReference type="OMA" id="EREIWRT"/>
    <dbReference type="OrthoDB" id="502701at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="392" mass="44632" checksum="F84FE86BBAC6819B" modified="2007-05-15" version="1">MAAHSREREEARREVVRETRYSFRCDMLDDAETSGVLNDELVEAWNSLLRENHISKDDETGDGFGARDDDDEDGDRVDCMDLDARFRAHVDACKTALEPKESLAARLKAHLVAEVDARFDDAIHEHRLEIGKARRLAAEERLTRKNAVEEVISNTKTTFGETSTRRDALRSEALAATDRSAAAEDADLSARSRREADARRASLIEIKLRNASEVSELRACLEHRVSEAFSRLQYAIARAPLRAERLRDAMKRRRGDEARRRARERLASRAMKDTRFELQEMKRCYTETERANAGRDRKLRLATLKTTSRVGSIESIGAKSERGDKMNAILSMKQTRIANLRRELDAAEEDVWLRALACNRPAFAKDVSLDEKCRAFEALERALRSETRQIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8X3</accession>
    <name>A4S8X3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EXPERA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421965.1">
        <property type="nucleotide sequence ID" value="XM_001421928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8X3"/>
    <dbReference type="GeneID" id="5006005"/>
    <dbReference type="Gramene" id="ABP00259">
        <property type="protein sequence ID" value="ABP00259"/>
        <property type="gene ID" value="OSTLU_27998"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27998"/>
    <dbReference type="eggNOG" id="ENOG502S4W9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1216202_0_0_1"/>
    <dbReference type="OMA" id="ICLWENA"/>
    <dbReference type="OrthoDB" id="496634at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673140" description="EXPERA domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26568" checksum="EE95AA7A645E41BB" modified="2007-05-15" version="1">MLAAVYVCGFVATLWLPFVCADARSRAPPSASVVEALAREANPKLALLLLFNAVNALICVWEIALWTHRANVQKLHRGYLKKFGNRVLPRPLCLFEDITLAQALSLKHWSIVFAQYASLDPSYVQHTSWSFWIDVGNGFTMLVPTVALSIAVTSWPEVPMIASFTPRSVGIVAIVMNYQMFYGTVMYYCNYCYNRYDVGASATSKVVVFAANLVWIVGPLAWIFYAVRFVHSNSLAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9A2</accession>
    <name>A4S9A2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_28133</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422027.1">
        <property type="nucleotide sequence ID" value="XM_001421990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9A2"/>
    <dbReference type="STRING" id="436017.A4S9A2"/>
    <dbReference type="GeneID" id="5006067"/>
    <dbReference type="Gramene" id="ABP00321">
        <property type="protein sequence ID" value="ABP00321"/>
        <property type="gene ID" value="OSTLU_28133"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28133"/>
    <dbReference type="eggNOG" id="KOG2042">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003224_2_1_1"/>
    <dbReference type="OMA" id="WLTEIAM"/>
    <dbReference type="OrthoDB" id="20295at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd16658">
        <property type="entry name" value="RING-Ubox_UBE4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="12">
        <location>
            <begin position="864"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="689"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="698"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="940" mass="107211" checksum="BA13B2F73183A2C1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9F9</accession>
    <name>A4S9F9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422058.1">
        <property type="nucleotide sequence ID" value="XM_001422021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9F9"/>
    <dbReference type="GeneID" id="5006098"/>
    <dbReference type="Gramene" id="ABP00352">
        <property type="protein sequence ID" value="ABP00352"/>
        <property type="gene ID" value="OSTLU_18609"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18609"/>
    <dbReference type="HOGENOM" id="CLU_331878_0_0_1"/>
    <dbReference type="OrthoDB" id="10604018at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="739"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="863" mass="97035" checksum="8195324733D7BDAD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9S9</accession>
    <name>A4S9S9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_2338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422119.1">
        <property type="nucleotide sequence ID" value="XM_001422082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9S9"/>
    <dbReference type="STRING" id="436017.A4S9S9"/>
    <dbReference type="GeneID" id="5006282"/>
    <dbReference type="Gramene" id="ABP00436">
        <property type="protein sequence ID" value="ABP00436"/>
        <property type="gene ID" value="OSTLU_2338"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2338"/>
    <dbReference type="eggNOG" id="KOG1427">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005210_7_2_1"/>
    <dbReference type="OMA" id="HELPERC"/>
    <dbReference type="OrthoDB" id="297375at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028641">
        <property type="entry name" value="RCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207:SF1">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="60"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="112"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="171"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="239"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="341"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="399" mass="42381" checksum="36962D4231B01EF6" modified="2007-05-15" version="1" fragment="single">ELLYCGATDFASVGRQKTNESGAHADLVEPHRYATLADKTWTRVAGGAAATHCAAIDDEGRLYTWGRNERGQLGHGDYVSRGTPTRVEALGETRCASAACGKGHTVVVCENGDVYGFGSNKFGQLGCGTMKKQMKKGDAEDDKLTPVKALVTNGKSASCGAEFTAVVTRDGEVFTYGLPQYGQLGHGTDHEYNTSASSIKIVYEPQPHPKRVVANGFGERKIVKLACGTNHVACFDDAGKIWTWGNGGYGRLGHRVQKDEFAPKMVEIQGGDRNLVPADAVLGAGSTSTFVSALQGQMYAFGKLKTTGDNTMYPVPLMDLQGWVLRDFACGSVTFAGCAEKSAVTWGGGAYGELGYGPKGKKSSANPDLVPSLEGKTTRRVACGNGYTLFLVDKEDAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA70</accession>
    <name>A4SA70_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422329.1">
        <property type="nucleotide sequence ID" value="XM_001422292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA70"/>
    <dbReference type="STRING" id="436017.A4SA70"/>
    <dbReference type="GeneID" id="5006386"/>
    <dbReference type="Gramene" id="ABP00646">
        <property type="protein sequence ID" value="ABP00646"/>
        <property type="gene ID" value="OSTLU_93986"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93986"/>
    <dbReference type="HOGENOM" id="CLU_539267_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="54617" checksum="05E566D940E83509" modified="2007-05-15" version="1" fragment="single">VDRAAKPSQRLSSPRERCPTTPSTPLASNAARGAIDPRVRERFRRGDDRRARTTLGAWRHRPSSNERTISRSPPRPPDPSRLTAFFAFRRPAQPVAHDSTLKRVTVANDDGDVYVESVGTDAEIVLKTQKVRVDGDVYCGASSSVGISSRVDTVESTHAALESRVNALNATEVELSAVMTSRLDALNATNAELKASDVAMTSRLDALNATNAELKANETALLSRINELLARVDALSNSTLPPKCIPPGGEKLQYDGTQWTCVCAGSWSGETCETPPSPPPSPPPSPPPPSPNQVSQTTQSGRPSSSDVWYRSPSYSGSSRPSETVVKERVFSFSATCAASTWVSDYTQCGEGAWREVGMAYSKTSGSIGLGWETIDGQPCLEKDEPDRTFNTGFCNHWHCWIDACGPSGDSFYGTNNNWITISGWYALASGSYTMSLIFDDSCDVYLESSTSSWTKIFAHGSDASSVVFSVSNGGEYRFVFVLGNGAYSAVVAITSFESSVDGTYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA76</accession>
    <name>A4SA76_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA76"/>
    <dbReference type="GeneID" id="5006391"/>
    <dbReference type="Gramene" id="ABP00651">
        <property type="protein sequence ID" value="ABP00651"/>
        <property type="gene ID" value="OSTLU_28458"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28458"/>
    <dbReference type="HOGENOM" id="CLU_3145068_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="49" mass="5694" checksum="AC30FE9AF316E78B" modified="2007-05-15" version="1">MGFMPFIPRIKSGRLLYSNLPDFMRGMNGINQLIYVVIPLNSEAPYVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAF6</accession>
    <name>A4SAF6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CAF17 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_28552</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422379.1">
        <property type="nucleotide sequence ID" value="XM_001422342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAF6"/>
    <dbReference type="STRING" id="436017.A4SAF6"/>
    <dbReference type="GeneID" id="5006437"/>
    <dbReference type="Gramene" id="ABP00696">
        <property type="protein sequence ID" value="ABP00696"/>
        <property type="gene ID" value="OSTLU_28552"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28552"/>
    <dbReference type="eggNOG" id="KOG2929">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_7_1_1"/>
    <dbReference type="OMA" id="LECNFDA"/>
    <dbReference type="OrthoDB" id="498687at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057460">
        <property type="entry name" value="CAF17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GCV_T_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602:SF0">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25455">
        <property type="entry name" value="Beta-barrel_CAF17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="CAF17 C-terminal" evidence="4">
        <location>
            <begin position="214"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="306" mass="32895" checksum="22BFC19CB6FCAD82" modified="2007-05-15" version="1">MRPSGRLLRAFKGWLDTRAVVRVAGADAAAFLQGAVTNDVRALREGGDAAYCATLTPKGKIFADAFVRLAGSESDEFLLDVDREKSSEFLRALRMLSLRKRVTIEDANEHRVVVASADADVGDSSARAVRRDERLEQLGFRGIVPASDAAWRDAVADAHARTRIALGVAEGASELANALPLECNFDALNGVSFTKGCYVGQENTARQRFRGVVRKRIAPFVAIEPGARAPSVGGKIVNERGDVVGDVIAAIEDEDAVLGLVRARMSFIRAHVAGEPGSAFRIADGARVGVEPPSWWPTEWLDAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAQ0</accession>
    <name>A4SAQ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alfin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422648.1">
        <property type="nucleotide sequence ID" value="XM_001422611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAQ0"/>
    <dbReference type="STRING" id="436017.A4SAQ0"/>
    <dbReference type="GeneID" id="5006530"/>
    <dbReference type="Gramene" id="ABP00965">
        <property type="protein sequence ID" value="ABP00965"/>
        <property type="gene ID" value="OSTLU_29338"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29338"/>
    <dbReference type="eggNOG" id="KOG1632">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1043496_0_0_1"/>
    <dbReference type="OMA" id="ARIELFW"/>
    <dbReference type="OrthoDB" id="495896at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045104">
        <property type="entry name" value="Alfin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021998">
        <property type="entry name" value="Alfin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12321">
        <property type="entry name" value="CPG BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12321:SF98">
        <property type="entry name" value="PHD FINGER PROTEIN ALFIN-LIKE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12165">
        <property type="entry name" value="Alfin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alfin N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="267" mass="29579" checksum="A196091FF4B969F8" modified="2007-05-15" version="1">MEAPRTVDEVHANFSRRRDGLVKALTRDVEAFYAQCDPDKENLCLYGNPDGTWDVQLPAEEVPPELPEPALGINFARDGMQRKDWLALVAVHSDAWLMAVAFYYGAKFDAKKRDALFAQINAVPTVYETLSAAHGREEKPTSAGARQNGGAQANGRDATGKGAKTALADVKGNSSKVKKHKVDPMDAQGFKKPSPGFILDPDQALTTLKNAQIELFWPDDNLWYRAEVISLNERNRTAKVLYATSDVETLNLDELIREGHVNVRREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAV4</accession>
    <name>A4SAV4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_43765</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422505.1">
        <property type="nucleotide sequence ID" value="XM_001422468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAV4"/>
    <dbReference type="STRING" id="436017.A4SAV4"/>
    <dbReference type="GeneID" id="5006726"/>
    <dbReference type="Gramene" id="ABP00822">
        <property type="protein sequence ID" value="ABP00822"/>
        <property type="gene ID" value="OSTLU_43765"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43765"/>
    <dbReference type="eggNOG" id="ENOG502QQZA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009621_2_1_1"/>
    <dbReference type="OrthoDB" id="16911at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17916">
        <property type="entry name" value="DEXHc_UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="UVRABC SYSTEM PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029:SF0">
        <property type="entry name" value="UVRABC SYSTEM PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0228">DNA excision</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="518"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="690" mass="76054" checksum="2228B43495500F8F" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB31</accession>
    <name>A4SB31_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_43691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422544.1">
        <property type="nucleotide sequence ID" value="XM_001422507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB31"/>
    <dbReference type="STRING" id="436017.A4SB31"/>
    <dbReference type="GeneID" id="5006764"/>
    <dbReference type="Gramene" id="ABP00861">
        <property type="protein sequence ID" value="ABP00861"/>
        <property type="gene ID" value="OSTLU_43691"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43691"/>
    <dbReference type="eggNOG" id="ENOG502RRF5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_846188_0_0_1"/>
    <dbReference type="OMA" id="WAQESSK"/>
    <dbReference type="OrthoDB" id="49436at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="354" mass="35961" checksum="16D8EBBFCCC7FF13" modified="2007-05-15" version="1" fragment="single">MTQVPVISSASSEPSSPVPGETPNAYPTQSPVPGETPNAYPTQSPVPGEAPNAYPTSSPNAYPTQSPVPGEAPNAYPTQSPVPGEAPNAYPTPSPNAYPTQSPVPGEAPNAYPTQSPVPGEAPNAYPTPSPNAYPTQSPVPGEAPNAYPTQSPVPGETPNAYPTSSPNAYPTQSPVPGEAPNAYPTQSPVPGEAPNAYPTPSPNAYPTQSPVPGEAPNAYPTQSPVPGETPNAYPTSSPNAYPTQSPVPGEAPNAYPTPSPNAYPTQSPVPGEAPNAYPTQSPVPGEAPNAYPTPSPNAYPTQSPAPNAYPTPSPNAYPTQSPVPGEAPNAYPTPSPNAYPTPSPSAYPTPSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB60</accession>
    <name>A4SB60_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_43679</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422560.1">
        <property type="nucleotide sequence ID" value="XM_001422523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB60"/>
    <dbReference type="STRING" id="436017.A4SB60"/>
    <dbReference type="GeneID" id="5006777"/>
    <dbReference type="Gramene" id="ABP00877">
        <property type="protein sequence ID" value="ABP00877"/>
        <property type="gene ID" value="OSTLU_43679"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43679"/>
    <dbReference type="eggNOG" id="KOG3285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072097_0_0_1"/>
    <dbReference type="OMA" id="WQFDVEI"/>
    <dbReference type="OrthoDB" id="1806at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.900.10:FF:000002">
        <property type="entry name" value="Mitotic spindle assembly checkpoint protein MAD2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF11">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="8">
        <location>
            <begin position="17"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="227" mass="25436" checksum="07010EE6627B1255" modified="2007-05-15" version="1">MAQEQRRGATSSAITLRGSTELVTEFFGYAVNTILYQRGVYPAEEFERKKKYGLGVMVTNEPKLKEYLVAALERVNAWLMEKDLKKLVLVLADAKTGETLERWTFDVETDAEIVDENGGDANGTTTTTTTTTTTTTTTTREKPEKEIMQEIQAIIRQITASVTFLPLLDRECAFELLAYTDAASATPEECEESDPKYVRDGVEMRLRSFSTKIHTVDAGVSYKTEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBE7</accession>
    <name>A4SBE7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_19120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422603.1">
        <property type="nucleotide sequence ID" value="XM_001422566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBE7"/>
    <dbReference type="STRING" id="436017.A4SBE7"/>
    <dbReference type="GeneID" id="5006821"/>
    <dbReference type="Gramene" id="ABP00920">
        <property type="protein sequence ID" value="ABP00920"/>
        <property type="gene ID" value="OSTLU_19120"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19120"/>
    <dbReference type="HOGENOM" id="CLU_1436633_0_0_1"/>
    <dbReference type="OrthoDB" id="58760at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37066">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37066:SF1">
        <property type="entry name" value="LNS2_PITP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21501" checksum="AA007A65187C16D6" modified="2007-05-15" version="1">MAYETPRDARAYSSANALKTYNMGFALGKRVNDIRAKGTFVEGRPDRFDALSKMQFVWDDEEFNWSQRLIPALQLYEQVHGHLNVPSAYAVPAKMPCPFGVARPVVVRRDLVGFELGSAVAQIRHWRFQRPGTSEGAARSRVRQLDRLSPLGFPWDVAEWERRARVLKRVRRRRVDARLASDAAASSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="115" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQE9</accession>
    <name>A4RQE9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Methionine aminopeptidase 2</fullName>
            <shortName evidence="11">MAP 2</shortName>
            <shortName evidence="11">MetAP 2</shortName>
            <ecNumber evidence="11">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_48274</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="11"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415721.1">
        <property type="nucleotide sequence ID" value="XM_001415684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQE9"/>
    <dbReference type="STRING" id="436017.A4RQE9"/>
    <dbReference type="GeneID" id="4999922"/>
    <dbReference type="Gramene" id="ABO94013">
        <property type="protein sequence ID" value="ABO94013"/>
        <property type="gene ID" value="OSTLU_48274"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48274"/>
    <dbReference type="eggNOG" id="KOG2775">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_7_1_1"/>
    <dbReference type="OMA" id="THVQGRI"/>
    <dbReference type="OrthoDB" id="7848262at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000106">
        <property type="entry name" value="Methionine aminopeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF2">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11 12" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="15">
        <location>
            <begin position="105"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO94013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="415" mass="46635" checksum="D64D1B6902EB2106" modified="2007-05-15" version="1">MTRDDDGANDDDDDDDAGDDGDDATREDGEATTATTKKKKKKKKKKKSAAAKQTRPPSTPVRELYPGAKYPAGEILPHREHNLWRETDEEKRELERLEENLYNEARQCAEVHREVRQYISDWVKPGMKYIDVCETLENSVRKLIEERGLEAGVAFPTGCSKNHVAAHWTPNGGCESVIDKDDVIKFDFGVQVKGRIIDCAFTKTFNDMYDPLLKAVNEATETGIRSAGIDVRLCDIGEAVQEVMESHTVEIHGKEYQVKCCSNLNGHSIDPYRIHAGKSVPIVKGGVQTKMEEGEYYAIETFGTTGRGYVIEDGECSHYMKNFDVGHVPLRLPRAKQLLGVIDRNFGTLAFCKRYLDRIGEQRYSMALKNLCDNGIVQPYPPLCDIKGSYVAQYEHTILLKPSSGVEVLTRGEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQG5</accession>
    <name>A4RQG5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415383.1">
        <property type="nucleotide sequence ID" value="XM_001415346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQG5"/>
    <dbReference type="GeneID" id="4999565"/>
    <dbReference type="Gramene" id="ABO93675">
        <property type="protein sequence ID" value="ABO93675"/>
        <property type="gene ID" value="OSTLU_28656"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28656"/>
    <dbReference type="eggNOG" id="ENOG502SE9I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096660_0_0_1"/>
    <dbReference type="OMA" id="AHTKHRY"/>
    <dbReference type="OrthoDB" id="498650at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="281" mass="29846" checksum="2FDBC432078BCD45" modified="2007-05-15" version="1">MTTRAPDDGDARRGRSTTGASSDAFVEGDAFEYARRTTANTTGQLTWPAARALAAFLDASDALRRAREVLELGSGNGWLGLAVLRARGARDVRVTMTETTEGGALRWLEARARANAAWGRIEGDDGARARCRALNWNAFSSDAAASDAGDAGDGEEGANADARGSARTEDETPLTADSPELADVDVVLGADLVYDDAGVVALPRVVKALLSRARSGAVFYYAHTKHRYDGMDLDFFANVSANGLTCEEVRPRGAPSPPPSPPPFESLFPDQRIAIYRIALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQL7</accession>
    <name>A4RQL7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
            <ecNumber evidence="2">7.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_39838</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415754.1">
        <property type="nucleotide sequence ID" value="XM_001415717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQL7"/>
    <dbReference type="SMR" id="A4RQL7"/>
    <dbReference type="GeneID" id="4999531"/>
    <dbReference type="Gramene" id="ABO94046">
        <property type="protein sequence ID" value="ABO94046"/>
        <property type="gene ID" value="OSTLU_39838"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39838"/>
    <dbReference type="eggNOG" id="ENOG502QPJC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008743_3_0_1"/>
    <dbReference type="OMA" id="QSRICKP"/>
    <dbReference type="OrthoDB" id="5210at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009705">
        <property type="term" value="C:plant-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009926">
        <property type="term" value="P:auxin polar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052546">
        <property type="term" value="P:cell wall pectin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048366">
        <property type="term" value="P:leaf development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000904">
        <property type="term" value="P:regulation of starch metabolic process"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009414">
        <property type="term" value="P:response to water deprivation"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005985">
        <property type="term" value="P:sucrose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
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        <property type="entry name" value="PRK00733.3-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="680"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="713" mass="74192" checksum="6D0DF152D1441899" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS00</accession>
    <name>A4RS00_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mg-protoporphyrin IX chelatase</fullName>
            <ecNumber evidence="10">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_29195</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>protoporphyrin IX + Mg(2+) + ATP + H2O = Mg-protoporphyrin IX + ADP + phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60492"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.6.1.1"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Redox regulation; active in reducing conditions, inactive in oxidizing conditions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The magnesium chelatase complex is a heterotrimer consisting of subunits CHLI, CHLD and CHLH.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The magnesium chelatase complex is a heterotrimer consisting of subunits CHLI, CHLD, AND CHLH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="10"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS00"/>
    <dbReference type="STRING" id="436017.A4RS00"/>
    <dbReference type="GeneID" id="4999821"/>
    <dbReference type="Gramene" id="ABO94285">
        <property type="protein sequence ID" value="ABO94285"/>
        <property type="gene ID" value="OSTLU_29195"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29195"/>
    <dbReference type="eggNOG" id="ENOG502QRUY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016684_0_0_1"/>
    <dbReference type="OMA" id="PAKFIMI"/>
    <dbReference type="OrthoDB" id="34999at2759"/>
    <dbReference type="UniPathway" id="UPA00668"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000601">
        <property type="entry name" value="Mg-protoporphyrin IX chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011775">
        <property type="entry name" value="Mg_chelatase_ATPase-isu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02030">
        <property type="entry name" value="BchI-ChlI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF9">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLI-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="10" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="83"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="410"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="443" mass="47926" checksum="7CA0FE3178FA6CBD" modified="2007-05-15" version="1">MRCSSAPRRAPGAARARTTRAVADKTRARATAATTVGGRARASDARRATVTRAKSESASFPFVKIVAQEELKLALTLNVVDSAIGGVLIMGDRGTAKSVSVRSLVQLLPEIDVVKNDPFNSSPTNPELMGPDVREAFQRGETLETAKMRVPMVEVPLGTTEDRICGTIDIEKALSEGTKAYDPGLLAKANRGLLYIDEVNLLDDSLVDVVLDSAAGGWNTVEREGISLTHPAKFIMIGSGNPEEGELRPQLLDRFGMAVNIRTIFDMDQRTELVMNKLAYERDPKGYTEECREETEALKAKIVAAQKLLPSVTMDRDFALKISGVCALVNVDGLRGDIVVTRAAKALVAFEGRTEVTMEDIARVIGPCLSHRLRKDVTDTMDGGFKVTLAFNKIFKGSAMLNFDETMAEGIKAPEPEKPKEAAKPKEEPKKKAGAWSGLPGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS38</accession>
    <name>A4RS38_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_2540</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416011.1">
        <property type="nucleotide sequence ID" value="XM_001415974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS38"/>
    <dbReference type="STRING" id="436017.A4RS38"/>
    <dbReference type="GeneID" id="5000030"/>
    <dbReference type="Gramene" id="ABO94303">
        <property type="protein sequence ID" value="ABO94303"/>
        <property type="gene ID" value="OSTLU_2540"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2540"/>
    <dbReference type="eggNOG" id="ENOG502QQ63">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036862_1_0_1"/>
    <dbReference type="OMA" id="MGKPSPF"/>
    <dbReference type="OrthoDB" id="2502820at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901974">
        <property type="term" value="F:glycerate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043879">
        <property type="term" value="F:glycolate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042631">
        <property type="term" value="P:cellular response to water deprivation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048527">
        <property type="term" value="P:lateral root development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009853">
        <property type="term" value="P:photorespiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:response to abscisic acid"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:stomatal movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007300">
        <property type="entry name" value="CidB/LrgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249:SF0">
        <property type="entry name" value="PLASTIDAL GLYCOLATE_GLYCERATE TRANSLOCATOR 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249">
        <property type="entry name" value="PUTATIVE SEROTONIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04172">
        <property type="entry name" value="LrgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="42183" checksum="3428F8BE7EC37271" modified="2007-05-15" version="1" fragment="single">AHLVASVGALFALDKGLENGLKAAGVSFPSALIGMFGALVILMVTEKLVGEDAANKLKSTVSPALNWITSWLPVFYVPSLVVTPLVLTKIAPSAIAKVLVIVVVGFVSTIAFSATSANAIRGMTGTTLLPVAPAKAAPPTEDYVYKMWGGILAVSTVAALATGANSAKVVTMLAATVCSFLVGNSPDVKAKMNPIVTTSVLANVYAAALGLVTGDGWMGMLGLYRTGVPFGLNNIAGLGAGDILMTFLGSVILSFAFKVFEARKIIARHAVEIFGCLVSTSMFAMFTTAVAGKYLGLSSALTAALVPRSVTVALAIPVTTLLGHPEMVSVTAAGVVLTGLIGSSLCIPILNKVGAKDPITRGLATAASAHGLGTAALVGSEPNALPYCALAYALSGIISSVLVAVPFIQAALIGIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS51</accession>
    <name>A4RS51_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">STI1/HOP DP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_48392</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415679.1">
        <property type="nucleotide sequence ID" value="XM_001415642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS51"/>
    <dbReference type="STRING" id="436017.A4RS51"/>
    <dbReference type="GeneID" id="4999690"/>
    <dbReference type="Gramene" id="ABO93971">
        <property type="protein sequence ID" value="ABO93971"/>
        <property type="gene ID" value="OSTLU_48392"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48392"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057418_1_0_1"/>
    <dbReference type="OMA" id="FMQMAEK"/>
    <dbReference type="OrthoDB" id="539167at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="STI1/HOP DP" evidence="5">
        <location>
            <begin position="145"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="260"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="293"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="352" mass="37797" checksum="DFABFDA720451B79" modified="2007-05-15" version="1">MAGDLPPGFGLPPGMAMPTGGGGSPFDMAKLREMLDDPAIKEMAEQISSDPNFKVMAEQMQANMANMQAQMGALPPGMGMPAGGMTGMMPGMPGMGGMPGMDQPAAMEAMQGVMQNPAFMQMAQKLGEQMMENPEMKAMMNTMNDPETAEKMKAKMEELKNDPEMSEIMKEIETGGPQAMMKYWNDPKVLKKINAAMGDVAPMFGGGVPAEEADEEEDEEDEEEEGEEEESVLTAASEGDHEALQAFLKEGQDVNMKDSEGRTALHFACGYGEMKCAEILVKEGSDVNATDKNKNTPLHYAAGYGRVDLVELLVEGGASVTLVNNDGKSPLDVAKLNDQDDVVKALEKDVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSF7</accession>
    <name>A4RSF7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lumenal PsbP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PSBP5</name>
        <name evidence="3" type="ORF">OSTLU_44991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416253.1">
        <property type="nucleotide sequence ID" value="XM_001416216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSF7"/>
    <dbReference type="STRING" id="436017.A4RSF7"/>
    <dbReference type="GeneID" id="5000362"/>
    <dbReference type="Gramene" id="ABO94546">
        <property type="protein sequence ID" value="ABO94546"/>
        <property type="gene ID" value="OSTLU_44991"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44991"/>
    <dbReference type="eggNOG" id="ENOG502QS0I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075416_0_0_1"/>
    <dbReference type="OMA" id="VLYPIQG"/>
    <dbReference type="OrthoDB" id="414405at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040946">
        <property type="entry name" value="PSII_PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF16">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="2">
        <location>
            <begin position="78"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="262" mass="28484" checksum="64DF9C72ABA32C81" modified="2007-05-15" version="1">MTRAVGARAPVRVVASGRRTAPSTRRVAIGVGASAALALGANFLGVTSRTLTAFAPEFARAKRLDALFPVDGFARCYAPRAGYEFVVPMDWLVDQTVTLRNARRGVESLDPPELRKGRAREVSEPDAAYGPRGTSGEENVSVIRSSVPRGFDLSVFGDANRQAEWLLANVLAKPGSGKTGELLSASQRKGSNGTVYYTFEYTIRKGDGAAPDGWFRHNIGVFAVRGDQLYTFVAQIPEERWPKMKETFFAMAESFRVFVPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RST9</accession>
    <name>A4RST9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Smo4</name>
        <name evidence="2" type="ORF">OSTLU_119583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416435.1">
        <property type="nucleotide sequence ID" value="XM_001416398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RST9"/>
    <dbReference type="STRING" id="436017.A4RST9"/>
    <dbReference type="TCDB" id="8.A.86.1.2">
        <property type="family name" value="the chloroplast trigalactosyldiacylglycerol-5 (tgd5) family"/>
    </dbReference>
    <dbReference type="GeneID" id="5000250"/>
    <dbReference type="Gramene" id="ABO94728">
        <property type="protein sequence ID" value="ABO94728"/>
        <property type="gene ID" value="OSTLU_119583"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119583"/>
    <dbReference type="HOGENOM" id="CLU_2695053_0_0_1"/>
    <dbReference type="OMA" id="QYHSSGV"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053288">
        <property type="entry name" value="TGD_Bridge_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34201">
        <property type="entry name" value="GLYCINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34201:SF12">
        <property type="entry name" value="PROTEIN TRIGALACTOSYLDIACYLGLYCEROL 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="77" mass="7675" checksum="1F965ED0B0F6B667" modified="2007-05-15" version="1">MPPSKDRRLVGRGVGVGIGLGCGFGLGWGFGGVPIGFWGLGIGGGCGVGVGLAWGVGFGAGSKYINQYFLFRDVAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT56</accession>
    <name>A4RT56_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CobW C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_29990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416132.1">
        <property type="nucleotide sequence ID" value="XM_001416095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT56"/>
    <dbReference type="STRING" id="436017.A4RT56"/>
    <dbReference type="GeneID" id="5000413"/>
    <dbReference type="Gramene" id="ABO94424">
        <property type="protein sequence ID" value="ABO94424"/>
        <property type="gene ID" value="OSTLU_29990"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29990"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_0_1_1"/>
    <dbReference type="OMA" id="EPRVNRM"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF62">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="6">
        <location>
            <begin position="240"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="339" mass="36990" checksum="EA7558BE402CE4DB" modified="2007-05-15" version="1">MSAEDAIEKTPVTIVTGFLGAGKTTLVNHILRGQHGLQIAVIENEFGAVSIDDALVSENIKEKEDIISMDNGCVCCTVRGDLVRALLTLKDREKKFDAVIIETTGLADPAPVAFTFFINPEIAEHYRIDSILCLADAKHVAMHMEEEKPDGAVNEAVQQVAFADRILLNKIDLVNEEEIATLEKTIRSVNASADVIKTQNSVVDLGVVLGVNSFSLEKTLETDPSFLDENKENKHNLTGVSSVGIAVEGELDFAAMNEFMMNLLQANATNMYRSKGVLCFEGQGDAKFVFQGVHEQINFGPSASTWAEGEPRVNRMVFIGRNLDRKALEAGFRGCLATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTL2</accession>
    <name>A4RTL2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-amylase</fullName>
            <ecNumber evidence="6">3.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_2142</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Hydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 14 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.2" evidence="6"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416297.1">
        <property type="nucleotide sequence ID" value="XM_001416260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTL2"/>
    <dbReference type="STRING" id="436017.A4RTL2"/>
    <dbReference type="CAZy" id="GH14">
        <property type="family name" value="Glycoside Hydrolase Family 14"/>
    </dbReference>
    <dbReference type="GeneID" id="5000404"/>
    <dbReference type="Gramene" id="ABO94590">
        <property type="protein sequence ID" value="ABO94590"/>
        <property type="gene ID" value="OSTLU_2142"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2142"/>
    <dbReference type="eggNOG" id="ENOG502QTBX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016754_5_1_1"/>
    <dbReference type="OMA" id="ARENMYA"/>
    <dbReference type="OrthoDB" id="1660156at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016161">
        <property type="term" value="F:beta-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001554">
        <property type="entry name" value="Glyco_hydro_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31352">
        <property type="entry name" value="BETA-AMYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31352:SF31">
        <property type="entry name" value="BETA-AMYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01373">
        <property type="entry name" value="Glyco_hydro_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00750">
        <property type="entry name" value="BETAAMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="395"/>
            <end position="396"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601554-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601554-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="456" mass="50270" checksum="FCC6A204352104BB" modified="2007-05-15" version="1" fragment="single">VRVMLPLDCVARTTTRTTRETLAKALRSVADAGADGVMVDCWWGACEGERPRAYEWRGYLALCEMCRDAGLSVDVVLSFHACGDSVGDEGCEIGLPEWARGEPARENMYADRRGNVTEEYLSLWGDETRDARRGDRSPLECYRDFMAAFRAAFATFLTGSADAPPVISQVIIGLGPCGELRYPSYRAGDGWHFPGVGEFQAFDERARMSLAYEAAACGKPEWGRHPPVNGPSYNCDPEGNVFFAADGTGDWNTPYGKFFLSWYSRELVAHGERVLEHAVREFDGVDASLGIKCAGVHWWHGHPSRAAECTAGYYNATPSPPADGNGDVDMVLGCEPRGYSQIIDLCARFGVELTFTCVEMRDVEHSPEHMCSPEGLLAQVLREAAEAGVTVNGENALARFDVDAFAQIVRTDDTMMTSSSSPDTACVLGSFTYLRMCDELFEPQNFDRFARFVRDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU49</accession>
    <name>A4RU49_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_30495</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416612.1">
        <property type="nucleotide sequence ID" value="XM_001416575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU49"/>
    <dbReference type="STRING" id="436017.A4RU49"/>
    <dbReference type="GeneID" id="5001033"/>
    <dbReference type="Gramene" id="ABO94905">
        <property type="protein sequence ID" value="ABO94905"/>
        <property type="gene ID" value="OSTLU_30495"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30495"/>
    <dbReference type="eggNOG" id="KOG0289">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023894_1_1_1"/>
    <dbReference type="OMA" id="SLDQHWA"/>
    <dbReference type="OrthoDB" id="687049at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000027">
        <property type="entry name" value="Pre-mRNA-processing factor 19, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 15" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 15" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4 14" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="17">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="243"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="282"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="325"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="367"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO94905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="478" mass="51241" checksum="BB3551E3C2B0B378" modified="2007-05-15" version="1">MFCAISGAAPARPVVTPRGVLYERSLIVKAIEERGECPVTKESLSVDDLIELKAQKWVNPRPEATMSVPGLLSAFHNEWDALMLETHTLRKELQTTRQELSHALYQHDAACRVIARLMKERDDARDALANAKGSAKRSAAGDAEPESKKVKAGLPAAVVAKMNDVQKELSSGRKKREISSELATMGDISAYEAKVTQAVHKTSPAGINAVAIKAGDDNVIATAGNDHTVAIFDKVSSQRVQQLSGHSKKVLDVKFVGDNVLSCGADKVVKLWGADGSEIATFGDHTGDVTSVSVHPSNSYFVSTSTDKTWGFHDLTTSSCITLVNDDTDSAITCANFHPDGVILGAGTKDSVVKLWDAKDARKLLQLDGHASEITGLSFSENGYYLASAAKDGVKIWDLRKSKLVHEIECAGAQGVAFDHSGSYIATGGHNASVYQVKGKWELVKEFEVKKAVKAVAFGGDARSLVVASADHNLRIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU95</accession>
    <name>A4RU95_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exoribonuclease phosphorolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_14569</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416919.1">
        <property type="nucleotide sequence ID" value="XM_001416882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU95"/>
    <dbReference type="STRING" id="436017.A4RU95"/>
    <dbReference type="GeneID" id="5001062"/>
    <dbReference type="Gramene" id="ABO95212">
        <property type="protein sequence ID" value="ABO95212"/>
        <property type="gene ID" value="OSTLU_14569"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14569"/>
    <dbReference type="eggNOG" id="KOG1069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063514_2_3_1"/>
    <dbReference type="OMA" id="IARYEVH"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11372">
        <property type="entry name" value="RNase_PH_RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="17"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="260" mass="28234" checksum="2AD92E9FB2034CA0" modified="2007-05-15" version="1">MAPATALRGDGRSSEMLRRQRLHRHYVAGAHGSAEYAIDGTIVVATVHGPQKVKPWREEVERGIVEFELTSASGMTREEERACEARVRGAIEATVVRYDFPRLGLRATARIVSDDGNAEAACVNALCCALIDADVAMHGLICANACAILSDGTKVIDPTKREENEARAVVRACALSKYREKEEIAIVGCSTTGALTEEEYLESIAFIVDATASVVNFQKKSIARFELEGKFQEDGTKEAKRAKTASEDTPMEGMENKPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUM3</accession>
    <name>A4RUM3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Calcium-dependent protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_24253</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416697.1">
        <property type="nucleotide sequence ID" value="XM_001416660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUM3"/>
    <dbReference type="STRING" id="436017.A4RUM3"/>
    <dbReference type="GeneID" id="5001107"/>
    <dbReference type="Gramene" id="ABO94990">
        <property type="protein sequence ID" value="ABO94990"/>
        <property type="gene ID" value="OSTLU_24253"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24253"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_37_3_1"/>
    <dbReference type="OMA" id="VCIGPRR"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000178">
        <property type="entry name" value="Calcium-dependent protein kinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="35"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="336"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="372"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="408"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="446"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="53171" checksum="944F3DC2FA6B695D" modified="2007-05-15" version="1">MGVCGSSPAVPNPVGKTARPSSVLGRETPDVNDLFEFHEELGRGQFGTTFLVTEKATGRKCACKAISKRQLSNAEDIEEVRNEVRILHHLAGHEHVVELVGAYEGSKHVYIVMELLSGGELFDRIVEKGKYSEKDASETVRTIVETVQYCHELSVMHRDLKPENFVLKNKDKNSPVCAIDFGLSTFFRENQVFMDLVGSPYYVAPEVLRRRYSNESDVWSCGIILYILLSGVPPFWAQTEQGIFDAILQGALDLESDPWPKISAEAKELISGMLQADPKKRLTAAQVLKHPWVADPNVAPKTKLDNVVFKRFKNFAGISKFKRMGLMAMARTMTADEVAGLRELFKSFDTDNSGTISIDELRQGLKLKSAGPAMEELRTLMKTIDVDGSGELDYEEFIAATLAQSRQASDAAVRRAFDYFDTDGDGSITVQEFEQAFKKMSDVERANLGDIGELIASADTDGDGCIDFNEFMAMMKADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUT5</accession>
    <name>A4RUT5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_3811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a cytidine in 25S rRNA + S-adenosyl-L-methionine = a 5-methylcytidine in 25S rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47780"/>
            <dbReference type="Rhea" id="RHEA-COMP:11911"/>
            <dbReference type="Rhea" id="RHEA-COMP:11912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416728.1">
        <property type="nucleotide sequence ID" value="XM_001416691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUT5"/>
    <dbReference type="STRING" id="436017.A4RUT5"/>
    <dbReference type="GeneID" id="5000754"/>
    <dbReference type="Gramene" id="ABO95021">
        <property type="protein sequence ID" value="ABO95021"/>
        <property type="gene ID" value="OSTLU_3811"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3811"/>
    <dbReference type="eggNOG" id="KOG2360">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_7_3_1"/>
    <dbReference type="OMA" id="DMENIEW"/>
    <dbReference type="OrthoDB" id="435282at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000164">
        <property type="entry name" value="Methyltransferase NSUN5, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049561">
        <property type="entry name" value="NSUN5_7_fdxn-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF4">
        <property type="entry name" value="28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21148">
        <property type="entry name" value="NSUN5_fdxn-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="86"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="32260" checksum="3A39B23EF0F262AC" modified="2007-05-15" version="1" fragment="single">AARYSRTARVNTLKTTVDEAMEAFREDGYECAVDSLIDTLLVFPAGTDLHAHKLVKTGAVVLQGRASCLPAVALAPERGWACIDGCAAPGNKTTQLAALVGREGGVYAFDADARRLKRLKENAATTGSQGIIRAKCQDFLTVDPGNTVYASVRALLLDPSCSGSGTEVNRGDIMLRDALDEDDVEEIDAEADADEERVDKLAAFQKSVLKHAFCFPEVERVSYSTCSVHEKENEEVVRDVMDVAVEHGFKLAHALPKWHRRGIAIDGLSTEDARCLIRADPIEDDMEGFFVAIFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUT6</accession>
    <name>A4RUT6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_86791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUT6"/>
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    <dbReference type="Gramene" id="ABO95308">
        <property type="protein sequence ID" value="ABO95308"/>
        <property type="gene ID" value="OSTLU_86791"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86791"/>
    <dbReference type="eggNOG" id="ENOG502S1I9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092231_0_0_1"/>
    <dbReference type="OMA" id="WAIPLRK"/>
    <dbReference type="OrthoDB" id="495663at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018706">
        <property type="entry name" value="DUF2214_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09980">
        <property type="entry name" value="DUF2214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="19753" checksum="B8477D92B0C14C42" modified="2007-05-15" version="1" fragment="single">VASAFAAYGHYLGLVLVVGALTTEKWTVKAGMSEAEEQRLVVADSIYGIAGVLVLYTGYLRATEYGKGWEFYSHEPIFWVKMWLFTVMGSSSLFPTIKIIGRAAAKAKGEVEPMSEKLATRITKIVNGELLAVCSIPLAAALMSRGVAYAPDMPWQAGAAPIALTSLGLGVKYVKEALTWEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUY0</accession>
    <name>A4RUY0_OSTLU</name>
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        <recommendedName>
            <fullName evidence="5">Rubisco LSMT substrate-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_30782</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416748.1">
        <property type="nucleotide sequence ID" value="XM_001416711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUY0"/>
    <dbReference type="GeneID" id="5000758"/>
    <dbReference type="Gramene" id="ABO95041">
        <property type="protein sequence ID" value="ABO95041"/>
        <property type="gene ID" value="OSTLU_30782"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30782"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029671_1_0_1"/>
    <dbReference type="OMA" id="MVPVFDM"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF93">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rubisco LSMT substrate-binding" evidence="5">
        <location>
            <begin position="326"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="515" mass="56323" checksum="16BEB1CC1790030F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVJ5</accession>
    <name>A4RVJ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_14901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417150.1">
        <property type="nucleotide sequence ID" value="XM_001417113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVJ5"/>
    <dbReference type="GeneID" id="5001152"/>
    <dbReference type="Gramene" id="ABO95443">
        <property type="protein sequence ID" value="ABO95443"/>
        <property type="gene ID" value="OSTLU_14901"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14901"/>
    <dbReference type="HOGENOM" id="CLU_730342_0_0_1"/>
    <dbReference type="OrthoDB" id="70932at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="25"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="102"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="181"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="260"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="42380" checksum="1478F7C937A550AA" modified="2007-05-15" version="1">MPPGDARDGASALDVAARAASRAEDDAWDAHHDALLAWSVADGRDGACNAPWRATHAGLNIGAWLQNQRAKLRAKKMPRERATRLDALTAAGRLWIDAPGRKGWNEQLEKLAAWAEKTNGGVDYNAPVGTTHEGAKIGAWLATQRTRRRDGENARRPLKPEQAAALDALVLRGVLRCEKADPWPRKWALVLKWGEERANGEHFNVPYDYKDGDERVGVWLNTQRQRFRGGTTKNLPLTPWQTEQMQAMIDAGKLWVHAPDDVWEKKFALLLRWGKEKTRGVNYNVPQGEEYEGVNLGSWLSTQRARLLHETLGKNRPLSDDERRKLQKLIDDGKLRPSTPRGKNAAKGQGKRAPRGNLDDVDAALNVDLPHTSKRGRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVS3</accession>
    <name>A4RVS3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417197.1">
        <property type="nucleotide sequence ID" value="XM_001417160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVS3"/>
    <dbReference type="STRING" id="436017.A4RVS3"/>
    <dbReference type="GeneID" id="5001400"/>
    <dbReference type="Gramene" id="ABO95490">
        <property type="protein sequence ID" value="ABO95490"/>
        <property type="gene ID" value="OSTLU_31079"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31079"/>
    <dbReference type="eggNOG" id="ENOG502S6YD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169889_0_0_1"/>
    <dbReference type="OMA" id="ATMQTTR"/>
    <dbReference type="OrthoDB" id="7333885at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36343">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36343:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="105" mass="11382" checksum="5639C54DB079593B" modified="2007-05-15" version="1">MLTVTMKTATMQTTRAVVKRDTTRARGVARVTKRGRDGVRARATQDGKNGPKKLTRENEKEAWLSEMEREGANPLKDPMALIGIGGIMVPFIILAIASAAGFIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVV9</accession>
    <name>A4RVV9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_14987</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XK family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417478.1">
        <property type="nucleotide sequence ID" value="XM_001417441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVV9"/>
    <dbReference type="TCDB" id="2.A.112.2.1">
        <property type="family name" value="the kx blood-group antigen (kxa) family"/>
    </dbReference>
    <dbReference type="GeneID" id="5001171"/>
    <dbReference type="Gramene" id="ABO95771">
        <property type="protein sequence ID" value="ABO95771"/>
        <property type="gene ID" value="OSTLU_14987"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14987"/>
    <dbReference type="eggNOG" id="ENOG502SHJX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_326084_0_0_1"/>
    <dbReference type="OMA" id="ISAVNWM"/>
    <dbReference type="OrthoDB" id="567924at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018629">
        <property type="entry name" value="XK-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050895">
        <property type="entry name" value="XK-related_scramblase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16024">
        <property type="entry name" value="XK-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16024:SF28">
        <property type="entry name" value="XK-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09815">
        <property type="entry name" value="XK-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="604"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="82"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="707"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="720"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="884" mass="96784" checksum="54F3632C9F831068" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVX1</accession>
    <name>A4RVX1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="11">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_14998</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="11"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417222.1">
        <property type="nucleotide sequence ID" value="XM_001417185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVX1"/>
    <dbReference type="STRING" id="436017.A4RVX1"/>
    <dbReference type="CAZy" id="GT35">
        <property type="family name" value="Glycosyltransferase Family 35"/>
    </dbReference>
    <dbReference type="GeneID" id="5001499"/>
    <dbReference type="Gramene" id="ABO95515">
        <property type="protein sequence ID" value="ABO95515"/>
        <property type="gene ID" value="OSTLU_14998"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14998"/>
    <dbReference type="eggNOG" id="KOG2099">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010198_2_0_1"/>
    <dbReference type="OMA" id="GIEPCRC"/>
    <dbReference type="OrthoDB" id="9215500at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04300">
        <property type="entry name" value="GT35_Glycogen_Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000002">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000003">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000197">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468:SF30">
        <property type="entry name" value="ALPHA-1,4 GLUCAN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8 10 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO95515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="820" mass="93886" checksum="D14FC49A79F1FFE9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWZ5</accession>
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        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
    </protein>
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        <name evidence="7" type="ORF">OSTLU_9236</name>
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    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="96" mass="11640" checksum="AD6CD976A8EB37C5" modified="2007-05-15" version="1" fragment="single">NRDEKTFVGREWLASDLRNKSYEDLHELWYVLLKERNMLLTERYLARTNREPMRAPQRMTKVRKSMARIKLVLTERAREEAGGDPQKLFEMMRLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX93</accession>
    <name>A4RX93_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_31612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MPP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX93"/>
    <dbReference type="STRING" id="436017.A4RX93"/>
    <dbReference type="GeneID" id="5001696"/>
    <dbReference type="Gramene" id="ABO96250">
        <property type="protein sequence ID" value="ABO96250"/>
        <property type="gene ID" value="OSTLU_31612"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31612"/>
    <dbReference type="eggNOG" id="KOG2600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_477686_0_0_1"/>
    <dbReference type="OMA" id="ANDIMYN"/>
    <dbReference type="OrthoDB" id="445326at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="437"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="545"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="494"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="571" mass="62858" checksum="CF5FAB7F5FAD430D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXB4</accession>
    <name>A4RXB4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417720.1">
        <property type="nucleotide sequence ID" value="XM_001417683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXB4"/>
    <dbReference type="GeneID" id="5002127"/>
    <dbReference type="Gramene" id="ABO96013">
        <property type="protein sequence ID" value="ABO96013"/>
        <property type="gene ID" value="OSTLU_31635"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31635"/>
    <dbReference type="eggNOG" id="KOG4554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1079034_0_0_1"/>
    <dbReference type="OMA" id="AMASQWE"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="258" mass="28808" checksum="9F916163D0543C19" modified="2007-05-15" version="1">MAKIEEMTDADAAREAKTPNAKATEGTKTATTTTTTTTTTATGGKRDSTTAPKPTPPTISPKMFISPILLMGGKRMGIDYKDPAHVAKIRMCFVVAMTMLALCFAHLWVTMKKRKKKLEEDTCEVKVKDVQSGETKTEKVTLYEHDVREFRKVLMSNIMGGCMVSMLHFAFKVVPPLLLQSIMMPLNLWDGNLWQVHVLSRGEKDNAKLRRPWEEPEQKSPFAAFAEAMSPETKANPKAIDASQKKAKDAKKNPKHKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXE2</accession>
    <name>A4RXE2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">F-ATPase family transporter: protons (Mitochondrial)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_31663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417984.1">
        <property type="nucleotide sequence ID" value="XM_001417947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXE2"/>
    <dbReference type="STRING" id="436017.A4RXE2"/>
    <dbReference type="GeneID" id="5001858"/>
    <dbReference type="Gramene" id="ABO96277">
        <property type="protein sequence ID" value="ABO96277"/>
        <property type="gene ID" value="OSTLU_31663"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31663"/>
    <dbReference type="eggNOG" id="KOG1662">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085114_0_0_1"/>
    <dbReference type="OMA" id="VTTNWIN"/>
    <dbReference type="OrthoDB" id="496179at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23288" checksum="EC145BA6BCB55C3F" modified="2007-05-15" version="1">MLRRLARCATARSTLERTYATASAKGASGGDVKAPLQQFGTSGRYATALYVAATKAGSLAAVESEVAQLTALVEKDLKFKQFLMDPSMAKSKKLAGVKEFCAGAKFTPITSNFVATMAEYGRLKELHKISLRFEEQCMASRNEVKCVITTAQALTPAQLTKVTESIKGHAPSGSTLKIEAVVDPRLIGGLTASIGEKFFDLSLMTTVKKYEAVIAAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXJ0</accession>
    <name>A4RXJ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_7730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417760.1">
        <property type="nucleotide sequence ID" value="XM_001417723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXJ0"/>
    <dbReference type="STRING" id="436017.A4RXJ0"/>
    <dbReference type="GeneID" id="5001833"/>
    <dbReference type="Gramene" id="ABO96053">
        <property type="protein sequence ID" value="ABO96053"/>
        <property type="gene ID" value="OSTLU_7730"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7730"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_7_35_1"/>
    <dbReference type="OMA" id="ERADSYS"/>
    <dbReference type="OrthoDB" id="498515at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="201" mass="22784" checksum="C8E86688014CC28F" modified="2007-05-15" version="1" fragment="single">EVEVLAKLRHPNLLLFMGYCVEPPLICTEFMRRGSLHTILKSGNVLEPARNHAVAIAVARGMSYLHSRSPPILHLDLKSPNILVDEKWRVKIADFGLARMRQTTQVSAKSEFHGTPEWMAPEMLRAEDFDERADSYSFGVVLWELLTARKPWMDLHPMQIVAVVGYSERKLELPPEGVPAADHDFTILLSDLFRACAQKDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXP8</accession>
    <name>A4RXP8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_38397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418029.1">
        <property type="nucleotide sequence ID" value="XM_001417992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXP8"/>
    <dbReference type="GeneID" id="5002109"/>
    <dbReference type="Gramene" id="ABO96322">
        <property type="protein sequence ID" value="ABO96322"/>
        <property type="gene ID" value="OSTLU_38397"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38397"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_0_1"/>
    <dbReference type="OMA" id="NILHHWC"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF227">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="35372" checksum="01F17A7D3B3E74FD" modified="2007-05-15" version="1">MPRCWWPIGHLRGWLGPSGFGSKSSWRDVIADLDPGSASRNCVLITGATAGIGFETLKAFCSTGATVVVGARDEARAKALACELMSKTTSIVRVLRLDLSCSKSVHAFVDAFLALNLKLTVLVNNAGIMPCPFDADSHRDLAFHVKFLNHFVLTQLLLESFDPAGARVVNVTSEVYRFSYPEGIRFGKIDDDRAYDSVKSYAQSKLALLLWTRYQGEALRERGVQFFAVHPGSVATQGSARARKSSGWRGALLHCVGAPFVKSVECGAATTIYCALHPGASMYNRFGEYYFASCNPRGVREISRDATLARRLVEYAARELDASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXT7</accession>
    <name>A4RXT7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92778</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418052.1">
        <property type="nucleotide sequence ID" value="XM_001418015.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RXT7"/>
    <dbReference type="GeneID" id="5001786"/>
    <dbReference type="Gramene" id="ABO96345">
        <property type="protein sequence ID" value="ABO96345"/>
        <property type="gene ID" value="OSTLU_92778"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92778"/>
    <dbReference type="HOGENOM" id="CLU_240434_0_0_1"/>
    <dbReference type="OMA" id="STIMRCE"/>
    <dbReference type="OrthoDB" id="125363at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd00603">
        <property type="entry name" value="IPT_PCSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052387">
        <property type="entry name" value="Fibrocystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769:SF2">
        <property type="entry name" value="FIBROCYSTIN-L ISOFORM 2 PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769">
        <property type="entry name" value="POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="212"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="389"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="484"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="689"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="773"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="1523"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1716" mass="178900" checksum="3AA5DCF8425EC25E" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY93</accession>
    <name>A4RY93_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HMGB3504</name>
        <name evidence="6" type="ORF">OSTLU_31946</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418346.1">
        <property type="nucleotide sequence ID" value="XM_001418309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY93"/>
    <dbReference type="STRING" id="436017.A4RY93"/>
    <dbReference type="GeneID" id="5002289"/>
    <dbReference type="Gramene" id="ABO96639">
        <property type="protein sequence ID" value="ABO96639"/>
        <property type="gene ID" value="OSTLU_31946"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31946"/>
    <dbReference type="eggNOG" id="KOG0381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082854_10_2_1"/>
    <dbReference type="OMA" id="MKNMGGK"/>
    <dbReference type="OrthoDB" id="564408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="10539" checksum="F3E59349054F8614" modified="2007-05-15" version="1">MAKIAAKKTTKTKKTAVKAKKVKDPNAPKRPLSAYMFFAKDQRAAILKKNPSFGVTDVAKALGAQWAKTTDKSKYEAEAAKDKKRYEAAMAKYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYF6</accession>
    <name>A4RYF6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418378.1">
        <property type="nucleotide sequence ID" value="XM_001418341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYF6"/>
    <dbReference type="GeneID" id="5002438"/>
    <dbReference type="Gramene" id="ABO96671">
        <property type="protein sequence ID" value="ABO96671"/>
        <property type="gene ID" value="OSTLU_32011"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32011"/>
    <dbReference type="HOGENOM" id="CLU_1655091_0_0_1"/>
    <dbReference type="OrthoDB" id="10661183at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="17251" checksum="DB8BB08D817E792C" modified="2007-05-15" version="1">MKAGVRQTARMSGKDAMPTPKTLKACASALADERASTLVALDASAACEKALKATRGDDATYLQDAGELRDMLETVKRALDGANFRLFLFQVVFSLVVACALALASQPAVRESFRNLLNSSDRRQIEANARQSAPSRAPRVVVTPASPTRLSRVESKTRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYG3</accession>
    <name>A4RYG3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat Shock Protein 70, cytosolic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HSP70G</name>
        <name evidence="10" type="ORF">OSTLU_32019</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418384.1">
        <property type="nucleotide sequence ID" value="XM_001418347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYG3"/>
    <dbReference type="STRING" id="436017.A4RYG3"/>
    <dbReference type="GeneID" id="5002444"/>
    <dbReference type="Gramene" id="ABO96677">
        <property type="protein sequence ID" value="ABO96677"/>
        <property type="gene ID" value="OSTLU_32019"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32019"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_0_1_1"/>
    <dbReference type="OMA" id="PCKKKSE"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24028">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000012">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000020">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="102"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="711" mass="77750" checksum="55111DE3F772D7EB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYI9</accession>
    <name>A4RYI9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_9337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418400.1">
        <property type="nucleotide sequence ID" value="XM_001418363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYI9"/>
    <dbReference type="STRING" id="436017.A4RYI9"/>
    <dbReference type="GeneID" id="5002466"/>
    <dbReference type="Gramene" id="ABO96693">
        <property type="protein sequence ID" value="ABO96693"/>
        <property type="gene ID" value="OSTLU_9337"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9337"/>
    <dbReference type="HOGENOM" id="CLU_2519284_0_0_1"/>
    <dbReference type="OrthoDB" id="515727at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="85" mass="9640" checksum="B0FEC70A8C70A1BA" modified="2007-05-15" version="1" fragment="single">VFLGSFDNSHSAARAYDLGRISLGCRDDEELNFPVTHYTDDLQMLEELSIEEIAEMLVEASQNTERRTSRFRGVVAREGGFEARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYN3</accession>
    <name>A4RYN3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S11, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS11</name>
        <name evidence="6" type="ORF">OSTLU_32090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418420.1">
        <property type="nucleotide sequence ID" value="XM_001418383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYN3"/>
    <dbReference type="STRING" id="436017.A4RYN3"/>
    <dbReference type="GeneID" id="5002218"/>
    <dbReference type="Gramene" id="ABO96713">
        <property type="protein sequence ID" value="ABO96713"/>
        <property type="gene ID" value="OSTLU_32090"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32090"/>
    <dbReference type="eggNOG" id="KOG1728">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073626_0_2_1"/>
    <dbReference type="OMA" id="KVGECWP"/>
    <dbReference type="OrthoDB" id="1890621at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.1000:FF:000004">
        <property type="entry name" value="40S ribosomal proteins S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028333">
        <property type="entry name" value="Ribosomal_uS17_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_uS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032440">
        <property type="entry name" value="Ribosomal_uS17_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03630">
        <property type="entry name" value="uS17_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF9">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16205">
        <property type="entry name" value="Ribosomal_S17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS17 N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="158" mass="17753" checksum="182E22C6E136DC62" modified="2007-05-15" version="1">MAAEQHERAFQKQLGVNVGFASATKKKTPGKGGNRYYKNVGLGFKTPREAIEGTYIDKKCPFTGNVSIRGRILTGVVKSTKMNRTIVMRMDYLHFIRKYQRYEKRHTNISAHISPCFRCNEGDKVVVGQCRPLSKTVRFNTLKVIPSGSKAGKAFVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYR4</accession>
    <name>A4RYR4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoribulokinase/uridine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_41282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418437.1">
        <property type="nucleotide sequence ID" value="XM_001418400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYR4"/>
    <dbReference type="STRING" id="436017.A4RYR4"/>
    <dbReference type="GeneID" id="5002318"/>
    <dbReference type="Gramene" id="ABO96730">
        <property type="protein sequence ID" value="ABO96730"/>
        <property type="gene ID" value="OSTLU_41282"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41282"/>
    <dbReference type="eggNOG" id="KOG2878">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056986_1_0_1"/>
    <dbReference type="OMA" id="FWRSLHP"/>
    <dbReference type="OrthoDB" id="347435at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009853">
        <property type="term" value="P:photorespiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="39812" checksum="E4072A0501148E56" modified="2007-05-15" version="1">MAGDDASDASDDAWRAHVREVGLGLFRALARDARELSASEDAETAEEAARNRVYRYYVPVYEEVVQRLRMHRRKAGTTREGRTPKPMVVGVSAPQGCGKTTLTRTIVDMIKATPKKFLDDSAADESGNVTAVTLSIDDFYLAYEDQAALGEANPGNAMLRYRGNAGTHDLALGSRSLQSLARINDSDGETSKFLAPRYDKLARDGRGDRKPQSEWESVSAPLDVVLLEGWMLGFEPIESDRARAINPDLVVVNERLKEYKAALWGPDNVAWWIIFKVDDPAWVYDWRLEAERKANGGLDDSQVKDFVDRFMPAYEAYLPGLYVDPPPESLVVVVDKHREVLMVHVSTALDSADDAMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ28</accession>
    <name>A4RZ28_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_49799</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DExH box helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418258.1">
        <property type="nucleotide sequence ID" value="XM_001418221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ28"/>
    <dbReference type="STRING" id="436017.A4RZ28"/>
    <dbReference type="GeneID" id="5002588"/>
    <dbReference type="Gramene" id="ABO96551">
        <property type="protein sequence ID" value="ABO96551"/>
        <property type="gene ID" value="OSTLU_49799"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49799"/>
    <dbReference type="eggNOG" id="KOG0948">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002902_0_1_1"/>
    <dbReference type="OMA" id="IMLKNYN"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
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</entry>
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    <accession>A4RZ96</accession>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
                <person name="Salamov A."/>
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                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
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                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            <dbReference type="PubMed" id="17460045"/>
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            <strain evidence="2 3">CCE9901</strain>
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    </feature>
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    </feature>
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        <location>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO96586.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
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</entry>
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        <submittedName>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
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                <person name="Putnam N."/>
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                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Heijde M."/>
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                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">CCE9901</strain>
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        <property type="project" value="EnsemblPlants"/>
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        <property type="term" value="P:pantothenate import across plasma membrane"/>
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        <property type="project" value="EnsemblPlants"/>
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        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
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        <property type="entry name" value="P3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="SODIUM-BILE ACID COTRANSPORTER"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01758">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        <location>
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            <end position="107"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="199"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="292" mass="29897" checksum="FF5DE830F9F9FEA6" modified="2007-05-15" version="1" fragment="single">FPVFVALGALAGMCAPGTVSWFRGDAVTYALAGTMLGMGITLDLSDFRAVFGQPWKIGMGVALQYTVMPTLAFLVGKMFLANQSLAAGLILVGCCPGGTASNVVTFLAGASVPLSVVLTTVSTFMATVMTPTLTQHLAGTMIPVDGGGLFVSTCKVVLLPVVAGLVLKKYAPKFSETLEPFAPITAVLTVALICASIIGRTSTQILAAGPTLIAAVALLHTLGFGLGYFLSRSAGFSSKTSRTMSIEVGMQNSALGVVLASAHFADPLVAVPCAISATVHSVLGSMLAAFWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZI6</accession>
    <name>A4RZI6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418341.1">
        <property type="nucleotide sequence ID" value="XM_001418304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZI6"/>
    <dbReference type="GeneID" id="5002199"/>
    <dbReference type="Gramene" id="ABO96634">
        <property type="protein sequence ID" value="ABO96634"/>
        <property type="gene ID" value="OSTLU_15955"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15955"/>
    <dbReference type="eggNOG" id="ENOG502SF6S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1130630_0_0_1"/>
    <dbReference type="OMA" id="QEDMLWK"/>
    <dbReference type="OrthoDB" id="498841at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="246" mass="26833" checksum="052842F5C19D0C8D" modified="2007-05-15" version="1">MGKLLNKYANGRGLPANAERTARTFDAERRRKNGGGALDTFARGGGNAASTSRAGHGGATSGGKKWKSRAGAKPRLMRALRVSAKGHRALTAREVEKLIEPVLQPRRAKYGGQGFAKTSTFVNISCDDFLGEFTALFDEHVDGFNGKSYVKMGKAQEDMLWKQKLREKTRQEATGERQLAGAQPFEVAPDGEAKIKKKKRKMIESPTATTPKTKVDVDLQAQAIAAYRALKAKKAATQNNAAKWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZJ8</accession>
    <name>A4RZJ8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_24740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418584.1">
        <property type="nucleotide sequence ID" value="XM_001418547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZJ8"/>
    <dbReference type="STRING" id="436017.A4RZJ8"/>
    <dbReference type="GeneID" id="5003066"/>
    <dbReference type="Gramene" id="ABO96877">
        <property type="protein sequence ID" value="ABO96877"/>
        <property type="gene ID" value="OSTLU_24740"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24740"/>
    <dbReference type="eggNOG" id="ENOG502QQ6H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015262_0_0_1"/>
    <dbReference type="OMA" id="DNACEDT"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045012">
        <property type="entry name" value="NLP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055081">
        <property type="entry name" value="NLP1-9_GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32002">
        <property type="entry name" value="PROTEIN NLP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32002:SF41">
        <property type="entry name" value="PROTEIN NLP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22922">
        <property type="entry name" value="GAF_NLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="5">
        <location>
            <begin position="300"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="6">
        <location>
            <begin position="537"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="723" mass="79898" checksum="CBD30BE288BEA754" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZL3</accession>
    <name>A4RZL3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_32428</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPRBP/DCAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418815.1">
        <property type="nucleotide sequence ID" value="XM_001418778.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RZL3"/>
    <dbReference type="GeneID" id="5002750"/>
    <dbReference type="Gramene" id="ABO97108">
        <property type="protein sequence ID" value="ABO97108"/>
        <property type="gene ID" value="OSTLU_32428"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32428"/>
    <dbReference type="eggNOG" id="KOG1832">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_244384_0_0_1"/>
    <dbReference type="OMA" id="RAQHRQC"/>
    <dbReference type="OrthoDB" id="27563at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033270">
        <property type="entry name" value="VPRBP/DCAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13129:SF4">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13129">
        <property type="entry name" value="VPRBP PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="911"/>
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        </location>
    </feature>
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        </location>
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        </location>
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        <location>
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            <end position="952"/>
        </location>
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        </location>
    </feature>
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        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1566"/>
            <end position="1599"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1599" mass="176273" checksum="9E372CF7B4209471" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZR4</accession>
    <name>A4RZR4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32477</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418616.1">
        <property type="nucleotide sequence ID" value="XM_001418579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZR4"/>
    <dbReference type="GeneID" id="5003045"/>
    <dbReference type="Gramene" id="ABO96909">
        <property type="protein sequence ID" value="ABO96909"/>
        <property type="gene ID" value="OSTLU_32477"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32477"/>
    <dbReference type="HOGENOM" id="CLU_1167536_0_0_1"/>
    <dbReference type="OrthoDB" id="10628132at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="11"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="27580" checksum="77905CC83B899776" modified="2007-05-15" version="1">MHDTFGYGAQPGPAPGVYAPGEGANSGPGLMPFDGSSQKKRRNAAAERIKKTFNPWHLVLVFMTLFLYLSYYSRKEVVSKRRVRKHKDGLEGDLREVRARMTTLEHDLFVRSKEHETLTRELDSMRREHETTKHELEAKKIEVKEHVERAASKPVRAGDVSTCQKEVKTLKTEMELMRHKCRVTELELERAKHEAEFMKEHIREEVIKEDIEQLEKQIEIDEKAEAEAAAREEVSHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZT7</accession>
    <name>A4RZT7_OSTLU</name>
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        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_16034</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO97150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZT7"/>
    <dbReference type="STRING" id="436017.A4RZT7"/>
    <dbReference type="GeneID" id="5003059"/>
    <dbReference type="Gramene" id="ABO97150">
        <property type="protein sequence ID" value="ABO97150"/>
        <property type="gene ID" value="OSTLU_16034"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16034"/>
    <dbReference type="eggNOG" id="KOG2454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OMA" id="ILMRGTF"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="2"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="510" mass="55793" checksum="6F799B410AE61768" modified="2007-05-15" version="1">MRAEEVRERIAKAAKAQREWAKSSFATRRKLLRVIQRFILEEQDTICRVSARDSGKPLVDAAFGEVLVTLEKIRWLCNEGERWLKPEKRSTGAMMFYKKARVEYHPVGVMGAIVPWNYPFHNVFNPLVANLFAGNALVVKVSEYASWSSQYYGRVIDAALDAVGAPRDLVQIITGYGEAGSALVTGGVQKVVFVGSTGIGRKVMEAAAKTLTPVVLELGGKDPFIVCADADLKQCVPMALRGAFQSCGQNCAGAERFYVHEKIHDKFLAKVLESARKLRQGWALSSSVDCGAMCMPKQAQYVQSLIDDAVARGATVHVGGKIELGAQGGQFYPPTVISGITHDMRIAREEVFGPVLAIVKTKSDEESISLANDCDFGLGSNVFTRSTRRAEKLGSQLEAGMTSINDFCSTYMAQSLPFGGVKESGFDRFAGIEGLRGCCVPKSVVVDRFPWLMKTNIPPPLCYPVADNAFAFCKALSRMFFGLNVAQQFGGLLSLAKCFLMPSNSYTKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S048</accession>
    <name>A4S048_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418681.1">
        <property type="nucleotide sequence ID" value="XM_001418644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S048"/>
    <dbReference type="STRING" id="436017.A4S048"/>
    <dbReference type="GeneID" id="5002999"/>
    <dbReference type="Gramene" id="ABO96974">
        <property type="protein sequence ID" value="ABO96974"/>
        <property type="gene ID" value="OSTLU_32615"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32615"/>
    <dbReference type="HOGENOM" id="CLU_1339467_0_0_1"/>
    <dbReference type="OrthoDB" id="10471224at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        </location>
    </feature>
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            <end position="104"/>
        </location>
    </feature>
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            <end position="185"/>
        </location>
    </feature>
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            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="205" mass="21510" checksum="14F0227E66AC4622" modified="2007-05-15" version="1">MHAQLACALLGTCGWQGTGYLAGVAAMSCFGLVAIETGKSGLLKYTAASCWYTLWLDIIWMASYATDNINKNNNWNSGHRRGNELCVGMVVLIFMLRFPQFFVWQKLWHLGFKASGGAGAQPSRYVDFATNPVARGQEMGSPRPQGDAFAQPPRATTATPSSALATAPVSPSPAPPAPVVSAPSPPAPISAPAVVSFTPSGPGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="5">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418687.1">
        <property type="nucleotide sequence ID" value="XM_001418650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S060"/>
    <dbReference type="STRING" id="436017.A4S060"/>
    <dbReference type="GeneID" id="5002761"/>
    <dbReference type="Gramene" id="ABO96980">
        <property type="protein sequence ID" value="ABO96980"/>
        <property type="gene ID" value="OSTLU_32626"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32626"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="45035at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27224" checksum="CA09253134F5C27B" modified="2007-05-15" version="1">MVKPNDDPKIFGYYDVSYVSVGEKQVGNPAGGRFRSPLGRFLFKTIGLEQNLFAPNKIENRVAFTLFGCLPGEVTLEGTFAPAEGVDDGRTVKASFGPPGISVAGGPKLRIGPKSSVVLSTTYLDDHVRLGKGSRGSLFVFTRKSEEKAERDHRRWGIGGLAIAIMLLTALGLGIFGVHELRTTSHTLYSVTVVLASAISLAMAYILRDGGIVAEDADLDDDVGELSEQQKAFLSRGRGDGENKGENVFSSQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0I9</accession>
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        <recommendedName>
            <fullName evidence="5">Protein ZIP4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418982.1">
        <property type="nucleotide sequence ID" value="XM_001418945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0I9"/>
    <dbReference type="STRING" id="436017.A4S0I9"/>
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        <property type="protein sequence ID" value="ABO97275"/>
        <property type="gene ID" value="OSTLU_93057"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93057"/>
    <dbReference type="HOGENOM" id="CLU_280523_0_0_1"/>
    <dbReference type="OMA" id="NEHPSMG"/>
    <dbReference type="OrthoDB" id="65716at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090173">
        <property type="term" value="P:regulation of synaptonemal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039057">
        <property type="entry name" value="Spo22/ZIP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375:SF2">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="903"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1120" mass="123760" checksum="3728A2A9D20FF4B0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0X3</accession>
    <name>A4S0X3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419262.1">
        <property type="nucleotide sequence ID" value="XM_001419225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0X3"/>
    <dbReference type="GeneID" id="5003385"/>
    <dbReference type="Gramene" id="ABO97555">
        <property type="protein sequence ID" value="ABO97555"/>
        <property type="gene ID" value="OSTLU_32898"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32898"/>
    <dbReference type="HOGENOM" id="CLU_2889880_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="63" mass="6776" checksum="03DDC22968EE86A4" modified="2007-05-15" version="1">MTIEYTPSESEEGEGGMFARLPSQGAGANAGLYEYEDDSDSSDDDVRHPRARDDAPSCCCVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S115</accession>
    <name>A4S115_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_32941</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419073.1">
        <property type="nucleotide sequence ID" value="XM_001419036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S115"/>
    <dbReference type="GeneID" id="5003356"/>
    <dbReference type="Gramene" id="ABO97366">
        <property type="protein sequence ID" value="ABO97366"/>
        <property type="gene ID" value="OSTLU_32941"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32941"/>
    <dbReference type="HOGENOM" id="CLU_817333_0_0_1"/>
    <dbReference type="OMA" id="VAPWERS"/>
    <dbReference type="OrthoDB" id="10613019at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="35869" checksum="9EB45D3A259EBB92" modified="2007-05-15" version="1">MDASTSLVDEYARLPLCARALVPYALVIGFVLNPLFSLDDFVAFCPGDILRRAQFHRVFASLLYIEGAFSTLLVAWAAFRVVAPWERSRGTLRTLSDAVAASVLANATTTCFATIVGAFVPAVFEVNFLGGTGVFTSCFVLFTREIARAPANTDLATPFGVAMPAKRAPYVTAVILVFLGGCNPLEVLACLYVGNAWAANGIVWATASDGTLAQLENGALRFASRQPGYVAVNGQMLPVDSRDSSSDNSSSTASSFVEGVAAMVSNAAREARRRFTETANRSAAPAAATTPAAPATADEAPSASRGVDTRPKPQTREERAAAFAAAFERRNSDDADDDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S142</accession>
    <name>A4S142_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419087.1">
        <property type="nucleotide sequence ID" value="XM_001419050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S142"/>
    <dbReference type="GeneID" id="5003370"/>
    <dbReference type="Gramene" id="ABO97380">
        <property type="protein sequence ID" value="ABO97380"/>
        <property type="gene ID" value="OSTLU_16379"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16379"/>
    <dbReference type="HOGENOM" id="CLU_1484382_0_0_1"/>
    <dbReference type="OMA" id="HASTWRE"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="182" mass="20580" checksum="2A5E154FC285A127" modified="2007-05-15" version="1">MSVSTSAHASTWREEKHEHAKDVARALRARCLERNIDSIFELDEFTDEALFTQLGESLLGASGRVPAKSFKHSAHFKSIVKHEYDAMYGDVRESKSDSEELASPRKSPPTRTSPRRRREDTTTVFERWKARLRVLEDVITFVALLAVCFVAGILLCDVCENHFQELAKPATREDDASPFATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S172</accession>
    <name>A4S172_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ARP3505</name>
        <name evidence="5" type="ORF">OSTLU_42575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419100.1">
        <property type="nucleotide sequence ID" value="XM_001419063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S172"/>
    <dbReference type="STRING" id="436017.A4S172"/>
    <dbReference type="GeneID" id="5003403"/>
    <dbReference type="Gramene" id="ABO97393">
        <property type="protein sequence ID" value="ABO97393"/>
        <property type="gene ID" value="OSTLU_42575"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42575"/>
    <dbReference type="eggNOG" id="KOG0676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_1_1_1"/>
    <dbReference type="OMA" id="FFEEYEC"/>
    <dbReference type="OrthoDB" id="6220758at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10210">
        <property type="entry name" value="ASKHA_NBD_Arp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000014">
        <property type="entry name" value="Putative actin-related protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.36.70">
        <property type="entry name" value="Actin, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="503" mass="56074" checksum="3686AF7F3B9A0DA9" modified="2007-05-15" version="1">MAPKRGARDGARAPSTAADRPAASSLRGDVTVVVDLGGSSLKLCVAEDGATATRSAPNASARVKASDGAGFVTLRGEEIDGVVDVNGLALRRPCDRGYVVHWEQQREILDDALRRTLGVDPTRCDLIITEPPFALPRTREALDEMVFEYFGFRRALVTTPAKLTKRFADFVDAKKRDAKDLCVVARSGVVLDCGFSFAHATAFVDGTEVPRGIKRLNLGGKALTNYLKELVSFRQWNMMDESAVIEDVKEKMCYVADDALAELEKCKAKRGGTVKREYVLPDGIHVLRGFVREDSANKRPKKKVPKEKKVKIPKKDEPEHQFLTLVNERFMVPEVLFHPSDIGGRQCGVAELVTQAVENEDLSNEAMRALAYLDVIVTGGCSKFPNFMERFERELRPLVSESYMLRIRQMDDPIQAACLGGVDIAKDREFFEKHALTKEEYLANKTSIRAAHESLEFEPNVRTGRLREYAATPNLKKLDKKRIIEDCEKLTPSFERDIIHASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1K5</accession>
    <name>A4S1K5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_42883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419381.1">
        <property type="nucleotide sequence ID" value="XM_001419344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1K5"/>
    <dbReference type="GeneID" id="5003219"/>
    <dbReference type="Gramene" id="ABO97674">
        <property type="protein sequence ID" value="ABO97674"/>
        <property type="gene ID" value="OSTLU_42883"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42883"/>
    <dbReference type="eggNOG" id="ENOG502S1JU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055713_0_0_1"/>
    <dbReference type="OMA" id="RFEKALM"/>
    <dbReference type="OrthoDB" id="286233at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044243">
        <property type="entry name" value="FLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47310">
        <property type="entry name" value="PROTEIN FLUORESCENT IN BLUE LIGHT, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47310:SF2">
        <property type="entry name" value="PROTEIN FLUORESCENT IN BLUE LIGHT, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="32283" checksum="1D0A8E53255DB62D" modified="2007-05-15" version="1">MTLGADAARAVKGPGEELLAKRLEEEAKSRERIDALYRELRAEEAKALELRREKEGEAQEELNKFREESEAQSRQQVLAGKTLCVTPFGIDIVGITEFVALAGAVASGISANQKKEEITMLNDKLRKINASLMSTSRASMGTDASVLEAARGGAAKAAAATMSSVDDWDTLSEDMKELKLALREGRKLLRADEFAAALNAFKKSLMLARVTGDLVSVRRATRGLGAAKRQLGDRVGAIADLKEVLNISQQLDDNTGDMDALGAIADLYTELGDLENAGRYYDLYLNQINDETVEIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1N3</accession>
    <name>A4S1N3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_16521</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419179.1">
        <property type="nucleotide sequence ID" value="XM_001419142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1N3"/>
    <dbReference type="STRING" id="436017.A4S1N3"/>
    <dbReference type="GeneID" id="5003234"/>
    <dbReference type="Gramene" id="ABO97472">
        <property type="protein sequence ID" value="ABO97472"/>
        <property type="gene ID" value="OSTLU_16521"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16521"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1130631_0_0_1"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="199"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="246" mass="28152" checksum="27D31C9DC7DE0FC8" modified="2007-05-15" version="1">MGDGERDWRERFLELTPSAVVEAATEMRRLLTVVELTRYISAHGGGEVPSNVSTSKWFAKTKVRREECPFCKKAFVAHYLAAHIATKHTGIKPVECHFKGCSECFVTTKDLDRHVALVHEHKHTCKLCGLPFSTKQAKEKHEAFGHAEGKSVACPVAGCGKMFKHADSMRAHVMQFHGDDSERRMYQCEHPDCDETFRTKRERTKHSKEVHSSTFPKKRRKPSTQTRLKSPTKMSRWLLDEDDDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1X9</accession>
    <name>A4S1X9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24976</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419226.1">
        <property type="nucleotide sequence ID" value="XM_001419189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1X9"/>
    <dbReference type="STRING" id="436017.A4S1X9"/>
    <dbReference type="GeneID" id="5003490"/>
    <dbReference type="Gramene" id="ABO97519">
        <property type="protein sequence ID" value="ABO97519"/>
        <property type="gene ID" value="OSTLU_24976"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24976"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_313185_0_0_1"/>
    <dbReference type="OMA" id="CERACHT"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46228">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46228:SF2">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_4G14350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="322"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="639"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="737"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="388"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="752"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="936" mass="101608" checksum="BCEDF5C1B709B6E1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2E9</accession>
    <name>A4S2E9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419520.1">
        <property type="nucleotide sequence ID" value="XM_001419483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2E9"/>
    <dbReference type="GeneID" id="5003739"/>
    <dbReference type="Gramene" id="ABO97813">
        <property type="protein sequence ID" value="ABO97813"/>
        <property type="gene ID" value="OSTLU_33431"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33431"/>
    <dbReference type="HOGENOM" id="CLU_581909_0_0_1"/>
    <dbReference type="OrthoDB" id="10471898at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="470" mass="52001" checksum="2263553397F017E2" modified="2007-05-15" version="1">MTRAEATESTEMEDDCDFVRELPGASGGLEEATLAAMRGVSLGDACAAAGVRTLARETRDGDAVIDRDAAAATTERALDAAMREKALVLERYEGRTHSVKAKEGSVQGAFQRAVFAKKLHERITTRVREEVRRRAESDLRTARRAAQERQLSGRRDAKAAMDAKREAPHKPWFLLETPKDEQMRLRKAAMVDAANAEAGADAGADASSSSWTMPGNVTIEPVPDTTDESVLGAVRMCIYMVQSHPRPIQKVLDYLFGYSPAVDGEDLEEIDAYSKGLPVSRGRMPADLAYSYAANLDKTLGERDKVALKALIKDVKEEWSSHIKAGFDAVKELESTPLDSAEDIRVQNRDSWLRAMFPTLDWPTRNEKNYKFMEHLREQQALDARTAVSTSRPVPLALSRANRAKQAQEQIQTYDLGGSKIHYSKDGVPIIAPDGFFPKANTAPSKRAETARIRLAASDAERRLAERRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2G3</accession>
    <name>A4S2G3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helicase MOV-10-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419744.1">
        <property type="nucleotide sequence ID" value="XM_001419707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2G3"/>
    <dbReference type="GeneID" id="5003745"/>
    <dbReference type="KEGG" id="olu:OSTLU_16728"/>
    <dbReference type="eggNOG" id="KOG1804">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_589999_0_0_1"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049080">
        <property type="entry name" value="MOV-10-like_beta-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21634">
        <property type="entry name" value="MOV-10_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase MOV-10-like beta-barrel" evidence="1">
        <location>
            <begin position="362"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="465" mass="51378" checksum="6CE7EC0F1E1F6F5A" modified="2007-05-15" version="1" fragment="single">MPVDGARAPTRCEVCDCDVPARLMPTHERGARHRAKLRTRDSLTWRCVACDASMPARARFEHERTRAHRSNARDARDALLGAYRCDVCDVDVPACGREEHERGAKHRAATFRRSAEAGAEATPKETLVPRKISSASDLKSASVVLKLPIDAGEKVTVLFGAFGLARDDLGDRVLEEPTLKTFEGEVKEGGMLEVENAVCLRDDWAKDLKAGVHDVSLVFSYRTYQDDVESGEITLSVLVLRLRARESAQESAERIALGPTSAFAYPKQQKNSSLVKGSKKVVDPGPSKEVLNAKTKFFWPAPLSVPMADIRKALDGEEPQASSVTEMLETGQKYLSKTNYAQFFRQLLMMEEVQATKNVRLYDMHNVALSQTNSKAMYRLFVPGLAEARPSVLRGDSIIVDLSTAKSSFRGKVEFVEAEHIVCRFHPGFTKAYINGVKADVSFEVSRTAIELMHGAIKDSLKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2M2</accession>
    <name>A4S2M2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AI-2E family transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_93242</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419773.1">
        <property type="nucleotide sequence ID" value="XM_001419736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2M2"/>
    <dbReference type="GeneID" id="5003614"/>
    <dbReference type="Gramene" id="ABO98066">
        <property type="protein sequence ID" value="ABO98066"/>
        <property type="gene ID" value="OSTLU_93242"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93242"/>
    <dbReference type="eggNOG" id="ENOG502T1SC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_558240_0_0_1"/>
    <dbReference type="OMA" id="WYSVWGA"/>
    <dbReference type="OrthoDB" id="415056at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716:SF53">
        <property type="entry name" value="PERMEASE PERM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="53764" checksum="1081FD0898B5EB87" modified="2007-05-15" version="1">MPRRGGTAPGARASAAHDDDEFAFPTSTSAPRESDDTPSPSRPFNFNENLSPSPIFAPGHHTASARDVTVITMGVAVIASACACWLLQVLAYLLRPLVTATGAALLLRPLVDFVSDAAYQRETLRRNRLRLCCPRVFTVPRIVAIVLALVVVCAVFGTLVWALYLGRVYFLVHWNDPDWNSRFTSRINDLGRSMSEMAKRVFKKDDVAEEAWARLLANIEATLKDEEFWETLGVGVFHYMQDIMLMLFYTLFLLAPRRELSRARSLVARRIHKATRRFVSIMVQIAVVRALSVGSLLGLCGVPWPLAIAVAIVSFWLFFIPTLGSIVASILPLPMIVLLPDLTERQRVAGSIIPNLVSFLVGDLIGPVVYRKGLDLNEVTVLLALVFWYSVWGAAGAVLGVPLTCALKIVLEEMPHEGAHALAAVMAPVQNDTTVNGDTASAVRVPMTLTFIAWLKRTCGRLFRPSGTTQPRRRADEEALLAESSSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2M6</accession>
    <name>A4S2M6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_2187</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419776.1">
        <property type="nucleotide sequence ID" value="XM_001419739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2M6"/>
    <dbReference type="STRING" id="436017.A4S2M6"/>
    <dbReference type="GeneID" id="5003557"/>
    <dbReference type="Gramene" id="ABO98069">
        <property type="protein sequence ID" value="ABO98069"/>
        <property type="gene ID" value="OSTLU_2187"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2187"/>
    <dbReference type="eggNOG" id="KOG0243">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_2_0_1"/>
    <dbReference type="OMA" id="QFFRTCG"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF29">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="1"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="20"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="343" mass="36908" checksum="C4173360E26BA5A8" modified="2007-05-15" version="1" fragment="single">VKALLMKTLDGYASAVFAYGQTGSGKTYTMLGRAGARRGASESASSTRDDVETASTSSPTMNDVGSDDGLIGRSIEYLFDALGREAAGGGEKAPTKVVVSVTSYEIYKEKVIDLLADESSKSLRVRWRSRDGFYVPNLSRRECANAGEALDCVREGAARRRVRSHKMNAESSRSHAVLTVHVERYFGAPRANGGGDRDDDVGASCDDSGDVEITRGKMTFVDLAGSERLKHSGSEDAGSRETSLINKSLFALGKVISILADESRDAKATTPHVPYRDSKLTKLLMDSLGGRSLTLMIACCSANERHVEETIRTLQYAARVTSIVNIPESNTSRTTETIDARAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="113" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2N3</accession>
    <name>A4S2N3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 6B homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_35070</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419562.1">
        <property type="nucleotide sequence ID" value="XM_001419525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2N3"/>
    <dbReference type="STRING" id="436017.A4S2N3"/>
    <dbReference type="GeneID" id="5003561"/>
    <dbReference type="Gramene" id="ABO97855">
        <property type="protein sequence ID" value="ABO97855"/>
        <property type="gene ID" value="OSTLU_35070"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35070"/>
    <dbReference type="eggNOG" id="KOG0727">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_2_0_1"/>
    <dbReference type="OMA" id="QDIGGMD"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000018">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000046">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000033">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="197"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="46799" checksum="19B5975CC44A211B" modified="2007-05-15" version="1">MERLTTTRAVCDDAQMPATHANASGATTTSEGSSTTTDLYARLKSLQRELELVEIQEEYIKDEQKNLKIELLRAQEEVKRIQSVPLVIGQFLEMVDAETGIISSTTGSNYYVRILSTLNRELLKPSSSVALHRHSNALVEILPPEADSSISLLSDAERPDVKYSDIGGADVQKQEIREAVELPLTHFDLYRQIGIDPPRGVLLYGPPGTGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEVDSIATARFDAHTGADREVQRILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIECPHPDRRQKRLVFQVCVNKMSLSDEVDLEDYVSRPDKISAADIRSICQEAGLQAVRKNRYVVLPKDFEVAYKTNVRKPDNDFEFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Q9</accession>
    <name>A4S2Q9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pirin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_34904</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419575.1">
        <property type="nucleotide sequence ID" value="XM_001419538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Q9"/>
    <dbReference type="STRING" id="436017.A4S2Q9"/>
    <dbReference type="GeneID" id="5003574"/>
    <dbReference type="Gramene" id="ABO97868">
        <property type="protein sequence ID" value="ABO97868"/>
        <property type="gene ID" value="OSTLU_34904"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34904"/>
    <dbReference type="eggNOG" id="ENOG502QQ5A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045717_0_2_1"/>
    <dbReference type="OMA" id="VAHRDNA"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="27"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="5">
        <location>
            <begin position="180"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="33091" checksum="C6D2D650CDDCE4C9" modified="2007-05-15" version="1">MATCGVAAPRAVVDVVLSREQGEGRGARVRRSIGTARLKHFDPFVMLDEFKVATPAGFPDHPHRGMTTVTYVLPNAGNGCVEHEDSVGNAGMLRPGDLQFMTAGRGILHAEVPENETTCHGLQLWVNLPAKHKMDAPEYQELRASELREASKDGVRAVVIAGEAFGAESQIRTKQAPMHYIHFTMSPSSRLVQNVPEGWNCLAYTLRGRADFGRCEDVDAHNTVTFSNEPGQDGVVVQTTSESAEFVLISGRPNDEPIVQHGPFVMNTREEISQAFADFQGGKNGFESVRGWRSEIQYRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2X3</accession>
    <name>A4S2X3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419820.1">
        <property type="nucleotide sequence ID" value="XM_001419783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2X3"/>
    <dbReference type="GeneID" id="5003879"/>
    <dbReference type="Gramene" id="ABO98113">
        <property type="protein sequence ID" value="ABO98113"/>
        <property type="gene ID" value="OSTLU_33600"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33600"/>
    <dbReference type="HOGENOM" id="CLU_659538_0_0_1"/>
    <dbReference type="OMA" id="CASAMCE"/>
    <dbReference type="OrthoDB" id="497431at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="46358" checksum="CBF50071C0B8F3A1" modified="2007-05-15" version="1">MTDVAHDVRVMFTSSADATVRAKTIAFRFDRTKRSKLVRATTTGTTGHMTRLTRVEDGDGRVSRACDTCLIEIHGVRFTRSIEPRLTKIVDAREVAQRQLGTLAERGAAVQLRFGNARDDDGRGTCEVLDGALTIDPLHPAMEACASAMCEVVAEGARSLGTRAASVGKNPEVWTPRKLEEGDEGYEKGKTKYEFAWSGEGKFAEEFGRYRGLQSEAEPLVRKIAERDRRVAALHLRIAHLEEIRRGLEVGSCGVIPEDCFTRRVVDADLIDRLHEGLTLTSQVTGESYNVRECGVYFDDLEDCDAEDLKSKITETQGQLALAQAVLRAMHEELQERVRWDSHESGVETRDVLENGVRREHMERLLGRGATKADVEASLKLPDRIRAKLVGGYDVDRCRKTGKYIAATADRGPARLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3E2</accession>
    <name>A4S3E2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420079.1">
        <property type="nucleotide sequence ID" value="XM_001420042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3E2"/>
    <dbReference type="GeneID" id="5004218"/>
    <dbReference type="Gramene" id="ABO98372">
        <property type="protein sequence ID" value="ABO98372"/>
        <property type="gene ID" value="OSTLU_26025"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26025"/>
    <dbReference type="eggNOG" id="ENOG502S63N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_981214_0_0_1"/>
    <dbReference type="OMA" id="MITERAT"/>
    <dbReference type="OrthoDB" id="407325at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF157">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 12 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="248" mass="26637" checksum="F702E1B6352A7DED" modified="2007-05-15" version="1">MKDVEPNDDGDEDEDVEVDPFFFDDGYDVAASTGFARVWEGAEALTAHLERTGLGRGERVLELGAGVGECGLACAALGAHVLLTDVRAVCENVIRRNIEQNGAGPATELLGAWPNATRIGSGSASRATLNWMDEIPSDPFQNSALTFRDADILIAAECVWLRELLLPFVTTSSTLLRSGVRELILSVRDRSSTEDASSGKAFPHTNEVVREFESTGCSVEALHRQRSEDEGKEIVIFRITSAAAAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3P7</accession>
    <name>A4S3P7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419956.1">
        <property type="nucleotide sequence ID" value="XM_001419919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3P7"/>
    <dbReference type="GeneID" id="5004086"/>
    <dbReference type="Gramene" id="ABO98249">
        <property type="protein sequence ID" value="ABO98249"/>
        <property type="gene ID" value="OSTLU_17059"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17059"/>
    <dbReference type="HOGENOM" id="CLU_960888_0_0_1"/>
    <dbReference type="OMA" id="HETDIMY"/>
    <dbReference type="OrthoDB" id="10505821at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="322" mass="35134" checksum="CE29FDFBDF1E6D2D" modified="2007-05-15" version="1">MAREDARGRVGAAAASSGRAGTNARDGAEARGTATLTVDVETAETEAEARERVRFFELCAPSALGTWTDERTCVVDVRGGIAALQGTGAELIAYLRDRLGVIMEVDAERERVLINHEIHNVVIEAARILHLQIEQAKMVTIAPTNGDEAATPTPKMGLSSSVDDDAVMQEVLGDIEPEELEELRRQLESKRATRQRLIETLGEPRVTCHLQPVELTSTLVRVRLPRTRSFTGDDPLYGVGVALRAVASTTQDGEPTWIFQCDMGGSKLHETDIMYISNNAISVPEVCRLVSGHKRRSVDKPRDVMDEFLPSCRTDVTQSSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3T0</accession>
    <name>A4S3T0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419974.1">
        <property type="nucleotide sequence ID" value="XM_001419937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3T0"/>
    <dbReference type="GeneID" id="5004156"/>
    <dbReference type="Gramene" id="ABO98267">
        <property type="protein sequence ID" value="ABO98267"/>
        <property type="gene ID" value="OSTLU_25153"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25153"/>
    <dbReference type="HOGENOM" id="CLU_822297_0_0_1"/>
    <dbReference type="OMA" id="HWADLWH"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="36363" checksum="B5AD8E5A2E8B4BA0" modified="2007-05-15" version="1">MPRPSRVARASSRVVARAPTSSARRVERRGAARDATLTRLGDATLPHPHDDHVRLDVYVGACRCGRASDARDVRLVLPESEEAVVDVYAALGRPNDDPHWADLWHGGVALATKIFETPELVRGKRVIDLGCGLGIAGIAAAMVGAREVVMTDREERALWCALAGCKANGVRDVREMPAVWNAPDDCALPTLPVFDDVRDCGSDCVVRAAKVDWFEPELAPGGFDVALACDVLYTPDAVDAIATLVLRLFEDDGGDGGKAIGASSSEGEGTFMLADPPGRFPKNHERFMSLMENPSRIPGFDGGGRRSIVRVTSSIEECLNLELETMAVKLSTYDIASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Y1</accession>
    <name>A4S3Y1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAC3/GANP/THP3 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420172.1">
        <property type="nucleotide sequence ID" value="XM_001420135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Y1"/>
    <dbReference type="STRING" id="436017.A4S3Y1"/>
    <dbReference type="GeneID" id="5003957"/>
    <dbReference type="Gramene" id="ABO98465">
        <property type="protein sequence ID" value="ABO98465"/>
        <property type="gene ID" value="OSTLU_26211"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26211"/>
    <dbReference type="eggNOG" id="KOG1860">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_817331_0_0_1"/>
    <dbReference type="OMA" id="HFAVARI"/>
    <dbReference type="OrthoDB" id="264795at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="1">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="37042" checksum="7A3A5E8BDE7217DC" modified="2007-05-15" version="1">MVKRFARTVVAGTEDAARVRTLDACERTVDHLFRALDDARRASTRASASASANALASAHAFCEDRLRAVRQDLAMQGLFADDPVACGRCCALLERMIVRAVTSEAEREADASDDDFGAAALRERQLGKTFGMLLSAYAELGFDDDLHVERVGRFVSMLLCVRLRDGTSELAGDLRRVGVRTLATKDARFAMTCRAAFATGNWRRFFAIVDEASYEHACCLERHFAVARIDALRSLNCALNSTPMKLDELARVLRLDYASDAETYVKACGLTVNVDESAEPTVQFRTSPFTPPNLSRPDVAAALRAANRGFKSSSPAAPAIDRDVASVDVDVHLASLSLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S401</accession>
    <name>A4S401_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420182.1">
        <property type="nucleotide sequence ID" value="XM_001420145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S401"/>
    <dbReference type="GeneID" id="5003967"/>
    <dbReference type="Gramene" id="ABO98475">
        <property type="protein sequence ID" value="ABO98475"/>
        <property type="gene ID" value="OSTLU_26232"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26232"/>
    <dbReference type="eggNOG" id="ENOG502SUPM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_718425_0_0_1"/>
    <dbReference type="OMA" id="NDSCAVE"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="113"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="385" mass="41902" checksum="FF7A138902006692" modified="2007-05-15" version="1">MTAAKDVFRAMCVARRAPRRRERERAEGESDAEAAAASAERANARDGKVRGPARATRAPRDAGGVTRFDFKREVVPVCEDGGELEMSTTNLGADARGRRGRADAPARAPRPLIVWAHGMRGDLSNDDQEGLWNFWSREDLGTCAVARYNARGYGRSSDVRRSREARWDARASDMLEVAQRIRNDDGGAVVFAGASLGGATAIWATVLAHESGRDAPKAVVVVTPPTFYDERESRKKKLRKRVATGDVTAPANSTTPRRVFQASKRPIDPPPPPLANPNDSCAVEVLIGSAQSNLPEPERVREALENVPVLVLAWDCGDTTHPVSSAMTLKDLAPHAEVVVASTRGEAGDEDYDIVHHVREHWSACIMEFIQRSLRRGGADDEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4E5</accession>
    <name>A4S4E5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA pseudouridine synthase</fullName>
            <ecNumber evidence="6">5.4.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_44228</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="6"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420422.1">
        <property type="nucleotide sequence ID" value="XM_001420385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4E5"/>
    <dbReference type="STRING" id="436017.A4S4E5"/>
    <dbReference type="GeneID" id="5004321"/>
    <dbReference type="Gramene" id="ABO98715">
        <property type="protein sequence ID" value="ABO98715"/>
        <property type="gene ID" value="OSTLU_44228"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44228"/>
    <dbReference type="eggNOG" id="KOG4393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014673_3_0_1"/>
    <dbReference type="OMA" id="FHKFVGQ"/>
    <dbReference type="OrthoDB" id="271910at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160147">
        <property type="term" value="F:tRNA pseudouridine(38-40) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="7">
        <location>
            <begin position="178"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="33445" checksum="FC827AA00B52F1CC" modified="2007-05-15" version="1">MVASKRIAAAVPRYLAFLEYDGARFRGFQRQCGVAATVQGALDEALTAFTGARGAIECVGSSRTDVGVHALRNSAHFDFARTTKDGTTVEPHDGASVRRGVNYHLRKLGAAVRVTECVRVDEMNPKFHARHDAVARRYRYDILVGERDDGGSLFDAERAWYVRATCDGRLNVDAMRDAAAALTGTHDFSSFRANGCQASSPVRTLTSIDVKEELTEWPAAEARGTKQKISIAVAAPSFLYHQVRLLAGALKAVGANDLTVKDVQELLEAKDVARAPQMAPAHGLYLADVAYLENYAVRPAYGARDEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4E9</accession>
    <name>A4S4E9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_17249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420254.1">
        <property type="nucleotide sequence ID" value="XM_001420217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4E9"/>
    <dbReference type="GeneID" id="5004322"/>
    <dbReference type="Gramene" id="ABO98547">
        <property type="protein sequence ID" value="ABO98547"/>
        <property type="gene ID" value="OSTLU_17249"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17249"/>
    <dbReference type="HOGENOM" id="CLU_1597222_0_0_1"/>
    <dbReference type="OMA" id="FYMCCDG"/>
    <dbReference type="OrthoDB" id="496699at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="167" mass="18619" checksum="ADD39B20252C7D6F" modified="2007-05-15" version="1">MRASARVASARAVVKRERDARSTRARAFVPPIVPNPRQGDDDANADAAPTLPNIERALAPHGWAIGAERGYDDTPHAFKIFKVRDGHHTLEQLQEALYVSDERGCRIRRETQSLFYMCCDGVRCRLNEGKKEIVVEMPCDLDSVGAYVAKAKVIEDIIKSSQKKRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="106" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4H0</accession>
    <name>A4S4H0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_26408</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420264.1">
        <property type="nucleotide sequence ID" value="XM_001420227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4H0"/>
    <dbReference type="STRING" id="436017.A4S4H0"/>
    <dbReference type="GeneID" id="5004466"/>
    <dbReference type="Gramene" id="ABO98557">
        <property type="protein sequence ID" value="ABO98557"/>
        <property type="gene ID" value="OSTLU_26408"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26408"/>
    <dbReference type="eggNOG" id="KOG0273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007609_1_1_1"/>
    <dbReference type="OMA" id="KWNKCGN"/>
    <dbReference type="OrthoDB" id="1367865at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.30:FF:000001">
        <property type="entry name" value="F-box-like/WD repeat-containing protein TBL1XR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000218">
        <property type="entry name" value="WD40 repeat-containing protein HOS15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045183">
        <property type="entry name" value="Ebi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846:SF2">
        <property type="entry name" value="F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="264"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="347"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="389"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="440"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="183"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="95"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="516" mass="56839" checksum="6828A6388F2F387F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4M0</accession>
    <name>A4S4M0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_50798</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420461.1">
        <property type="nucleotide sequence ID" value="XM_001420424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4M0"/>
    <dbReference type="STRING" id="436017.A4S4M0"/>
    <dbReference type="GeneID" id="5004585"/>
    <dbReference type="Gramene" id="ABO98754">
        <property type="protein sequence ID" value="ABO98754"/>
        <property type="gene ID" value="OSTLU_50798"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50798"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_7_35_1"/>
    <dbReference type="OrthoDB" id="339325at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="21"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="316" mass="35441" checksum="C5D5A6908015EB68" modified="2007-05-15" version="1">MELNTEWEIDYKDIEFEGGVPSSQNRIGHGGFGEVFLGRYHGSLVAVKKLFNQDMMGKGLSDFRREVQILSRLRHPSIVLWLGACTQAPNLTIVLEYMDKGSLHQFLHRTTTPYTTLTLTRWAMTIAQGMVYLHSAKPFPIVHCDLNTNNVLVNRDGMVKITDFGLSKVKHSSRLSRQTGMTGTVNYASPEVIRGGKFSEASDVFAYGVILWELLTRRIPWEDLNEYQIVFQMTSDLDASLAATAKNLELPASAPEGYRKIIHGAWATQPERRSAFKDVLGDLREVYREQVDIEKALRAARKGSTSSLSATSAPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4N0</accession>
    <name>A4S4N0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420295.1">
        <property type="nucleotide sequence ID" value="XM_001420258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4N0"/>
    <dbReference type="STRING" id="436017.A4S4N0"/>
    <dbReference type="GeneID" id="5004363"/>
    <dbReference type="Gramene" id="ABO98588">
        <property type="protein sequence ID" value="ABO98588"/>
        <property type="gene ID" value="OSTLU_26468"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26468"/>
    <dbReference type="eggNOG" id="KOG4374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1386218_0_0_1"/>
    <dbReference type="OrthoDB" id="76949at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="21360" checksum="8DE236109011919C" modified="2007-05-15" version="1">MPSKRASANGRVDRAATDRSRASTPRGVKTLKVRLARATKFRDENRIPVRDRLGDGAKTTKSAAKDLRRTIERATTTGDARTRAKGDVGPGDLRRRLPRRDDGAAANAKAKATRTSGDLRNALSGKSGRKGVANAKGRGDARVNALLRRLNLSSYEAAFAREEIDLIALRAMRDGDFDKLGLPYGVKVKLALALGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4V2</accession>
    <name>A4S4V2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_50814</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420330.1">
        <property type="nucleotide sequence ID" value="XM_001420293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4V2"/>
    <dbReference type="STRING" id="436017.A4S4V2"/>
    <dbReference type="GeneID" id="5004389"/>
    <dbReference type="Gramene" id="ABO98623">
        <property type="protein sequence ID" value="ABO98623"/>
        <property type="gene ID" value="OSTLU_50814"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50814"/>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_17_0_1"/>
    <dbReference type="OMA" id="WLYVGAK"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030586">
        <property type="term" value="F:[methionine synthase] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000007">
        <property type="entry name" value="Methionine synthase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000001">
        <property type="entry name" value="NADPH--cytochrome P450 reductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="401" mass="43782" checksum="03E9FEA1FC5760C7" modified="2007-05-15" version="1">MATIHKREVLTNLKSDRRVLHMEFDLGSSGISYKPGDSIGIVPQNDAELVRAIVDRLGLDQAAIFTLNWKKGDTNEHATHPLPHIHTPCTVKSVFTNYIDITGCPRKSLLRVLAEHCGNAEEKDALLHLSSRGGRAEYETQIRAQSPTLLTLLNNYPSCCPPLAELLDALSPLAPRLYSITCAPEVAPTTPSVAFSVVRFQVPSGEHRLGVATNWLDEISVDDKCEHKVPVYIKPSLKFGLPEDSSAPLVMIGPGTGVAPCRGFLQSRRAKAQKGGRLSEAMLFFGCRKADEDFLYEADWKSFTADGSLTKLVCAFSRETAEKVYVQHKIEEHATEVARLISEGAYVMVCGDGAHMAKDVHAALVRVVAQAGVCGVSDVKAAEALLADFTKSGRYVRDIWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S560</accession>
    <name>A4S560_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_88691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420553.1">
        <property type="nucleotide sequence ID" value="XM_001420516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S560"/>
    <dbReference type="STRING" id="436017.A4S560"/>
    <dbReference type="GeneID" id="5004292"/>
    <dbReference type="Gramene" id="ABO98846">
        <property type="protein sequence ID" value="ABO98846"/>
        <property type="gene ID" value="OSTLU_88691"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88691"/>
    <dbReference type="eggNOG" id="ENOG502SAPF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1186664_0_0_1"/>
    <dbReference type="OMA" id="FEGVCQG"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="234" mass="25961" checksum="87E7824837943440" modified="2007-05-15" version="1">MQSPARDETRTYDPYAVSPRVVSIDVECVANGTTHNDRAVAQIAIVDARTEQTLLNVYVKQEKPVVSYLTPLTGLTEQLLAERGVSFAEAVAATKKALDARCVIVGQGVLKDVEQWLGLVRGVDYGDLIDLCGIWRVFNAQYKSWSVFGQDHLVRCLLATEVAETHDAAGDCVKSVRLYRHWYALKDDDEKLACEKAKLLAIAPEPSFSKRFPSFEGVCQGNRRTCVCKAPFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S568</accession>
    <name>A4S568_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_25275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420718.1">
        <property type="nucleotide sequence ID" value="XM_001420681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S568"/>
    <dbReference type="STRING" id="436017.A4S568"/>
    <dbReference type="GeneID" id="5004635"/>
    <dbReference type="Gramene" id="ABO99011">
        <property type="protein sequence ID" value="ABO99011"/>
        <property type="gene ID" value="OSTLU_25275"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25275"/>
    <dbReference type="eggNOG" id="ENOG502S80V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_574143_0_0_1"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S593</accession>
    <name>A4S593_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">OSTLU_17487</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">CCE9901</strain>
        </source>
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        <property type="nucleotide sequence ID" value="XM_001420530.1"/>
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        <property type="gene ID" value="OSTLU_17487"/>
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            <begin position="1"/>
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            <begin position="1"/>
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            <begin position="139"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO98860.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="843" mass="96293" checksum="A38B2C616F1D14F7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5B7</accession>
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            <fullName evidence="3">J domain-containing protein</fullName>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">CCE9901</strain>
        </source>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="8"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="343" mass="37001" checksum="1419A99FC4D7CB64" modified="2007-05-15" version="1">MNRGRGKDFYAALGLQRGADENDVRKAYRKLAMKWHPDKNPDDKDGRAEKKFKEVSEAYEVLSDPKKKELYDTYGEDGLKDGGGMPGGGFSAQHAEDIFANFFGGGGGGFPGGGGFGGGFPGGGGFPGGGGFGGHPGFGGMPGGGGFGGQDFREPPQKQRKKAPKIEQTLRLSLEELFYGTQKNFSVTRKVIRNGRQESVQETLPIDVKPGWKSGTKITFQEKGDETPTTIAADIVFTLEQKPHPQFEREGNDLVKTVKVDLNEALLGTSFSVYTLDGKAMDVKVDDIISPTFVKVLPGEGMPLSKSPGERGDLKIKFHIRFPKSLGDDQRNALRDALAGATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5G5</accession>
    <name>A4S5G5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6 7">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_26758</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6 7"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420770.1">
        <property type="nucleotide sequence ID" value="XM_001420733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5G5"/>
    <dbReference type="STRING" id="436017.A4S5G5"/>
    <dbReference type="GeneID" id="5004688"/>
    <dbReference type="Gramene" id="ABO99063">
        <property type="protein sequence ID" value="ABO99063"/>
        <property type="gene ID" value="OSTLU_26758"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26758"/>
    <dbReference type="eggNOG" id="KOG1256">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_45_4_1"/>
    <dbReference type="OMA" id="KCPIVEH"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05927">
        <property type="entry name" value="LC-FACS_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045311">
        <property type="entry name" value="LC-FACS_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="630" mass="68728" checksum="7A5E17B0C8D0063B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5N2</accession>
    <name>A4S5N2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420638.1">
        <property type="nucleotide sequence ID" value="XM_001420601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5N2"/>
    <dbReference type="GeneID" id="5004668"/>
    <dbReference type="Gramene" id="ABO98931">
        <property type="protein sequence ID" value="ABO98931"/>
        <property type="gene ID" value="OSTLU_26824"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26824"/>
    <dbReference type="eggNOG" id="ENOG502S8AP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_724413_0_0_1"/>
    <dbReference type="OMA" id="ATIETMH"/>
    <dbReference type="OrthoDB" id="568235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="42823" checksum="0A2CF21C1288E89E" modified="2007-05-15" version="1">MRVVGAVSCAPTTSNQDDDDDDARAVASLRARLHAPRHGETLRAKCVRLRDAVRSRTCSSSEIKGRLARRAETSALAALERWATTARAIEVDLERIVRGDVDKKSLSAMGEEVTRALRDFEWYLREHDVMEDLPFVVDDDCETRSSDETTIDLMRKVLEKDVKDDDASILDTMCDELRARESDYAWRGALLGEVENQARARGWSSENFSYGSTPFASWVAVFVQCDELRERAKTLEEDDLKYVVFGSSAGWLVFYAATTFRGARCEGFEILETLHATASHVLEGAEKKACKKFNVNFCNADMLSSSLCDVGIIVLTSMCWDDAVYDAVLEKLAEELRAGAFVIDYRGNLAQKDKFALVSKDSLRAPVSWNPGQRFYVFKKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S653</accession>
    <name>A4S653_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycoprotease 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GCP2</name>
        <name evidence="9" type="ORF">OSTLU_17729</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420886.1">
        <property type="nucleotide sequence ID" value="XM_001420849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S653"/>
    <dbReference type="STRING" id="436017.A4S653"/>
    <dbReference type="GeneID" id="5005061"/>
    <dbReference type="Gramene" id="ABO99179">
        <property type="protein sequence ID" value="ABO99179"/>
        <property type="gene ID" value="OSTLU_17729"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17729"/>
    <dbReference type="eggNOG" id="KOG2708">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023208_2_2_1"/>
    <dbReference type="OMA" id="HHRSWVV"/>
    <dbReference type="OrthoDB" id="10254073at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:tRNA N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd24132">
        <property type="entry name" value="ASKHA_NBD_OSGEP_like_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000038">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000105">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01446">
        <property type="entry name" value="Kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034680">
        <property type="entry name" value="Kae1_archaea_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03722">
        <property type="entry name" value="arch_KAE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="8">
        <location>
            <begin position="48"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="149"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="374" mass="40374" checksum="0B5D60FF2E8BFC1F" modified="2007-05-15" version="1">MPDAASTRAAPTASTASSTTLAIGFEGSANKISVGVARADGTILANPRETYVTPPGTGFLPRETAKHHRDVVVELARRALEEAKASMRDVDAVCFTRGPGMGAPLTTAAACARTLALLFDKPLVGVNHCVAHIEMGRLVTGARDPVVLYASGGNTQVIAYNERRYRIFGETIDIAVGNMLDRFARVCGLSNDPAPGYNIEQEAKKGTKFIEGPYGVKGMDVNLSGILTFYETYAKEHLGAGEVTVADLCMSMQETVFSMLVEITERAMAHTNAKDVLIVGGVGCNLRLQEMMAIMASERGGKLYGLDEDGRMDDRFCIDNGAMIAYTGLLQYENGETTPLEKTWCTQRFRTDEVLVTWRSEAVKRPASCEPPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6X4</accession>
    <name>A4S6X4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27274</name>
        <name evidence="3" type="ORF">OSTLU_29637</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001421133.1"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6X4"/>
    <dbReference type="GeneID" id="5004941"/>
    <dbReference type="GeneID" id="5006843"/>
    <dbReference type="Gramene" id="ABO99463">
        <property type="protein sequence ID" value="ABO99463"/>
        <property type="gene ID" value="OSTLU_27274"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01144">
        <property type="protein sequence ID" value="ABP01144"/>
        <property type="gene ID" value="OSTLU_29637"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27274"/>
    <dbReference type="KEGG" id="olu:OSTLU_29637"/>
    <dbReference type="eggNOG" id="ENOG502SFIR">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1139597_0_0_1"/>
    <dbReference type="OMA" id="VESTAHM"/>
    <dbReference type="OrthoDB" id="502303at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
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        <property type="component" value="Chromosome 21"/>
    </dbReference>
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        <property type="entry name" value="PSPTO4464-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DarP_sf"/>
    </dbReference>
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        <property type="entry name" value="DarP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158710">
        <property type="entry name" value="PSPTO4464-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="244" mass="25750" checksum="56B393B6FA836BBA" modified="2007-05-15" version="1">MGRINKSALKRLAHEKKTMAKTLLALPKSQIATMEELNAEVKALVAEGKKLKGNHGAAKRHEGALAGALRRMTESEMDALVSKVTAIENGTTGAIDSNVDALAMSWRARLLSGTEATTASSDDATACLGEIFDALATAEANETSAPLSFTRQELKVALDAATKESRARALAIAEFNASIDKEMEVLAYGETNEEVLRETRAFIAQKLKSGGGASATPSRSPPRAKSSKRLLGMLRDVAAVVVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="111" xmlns="https://uniprot.org/uniprot">
    <accession>A4S712</accession>
    <name>A4S712_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">T-complex protein 1 subunit eta</fullName>
            <shortName evidence="9">TCP-1-eta</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-eta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_25463</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooligomeric complex that forms two stacked rings.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421192.1">
        <property type="nucleotide sequence ID" value="XM_001421155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S712"/>
    <dbReference type="STRING" id="436017.A4S712"/>
    <dbReference type="GeneID" id="5005378"/>
    <dbReference type="Gramene" id="ABO99485">
        <property type="protein sequence ID" value="ABO99485"/>
        <property type="gene ID" value="OSTLU_25463"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25463"/>
    <dbReference type="eggNOG" id="KOG0361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_7_1_1"/>
    <dbReference type="OMA" id="HRKGNTW"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03340">
        <property type="entry name" value="TCP1_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000022">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000006">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012720">
        <property type="entry name" value="Chap_CCT_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02345">
        <property type="entry name" value="chap_CCT_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="537"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="544"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="570" mass="61444" checksum="5058C56F90258C19" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S774</accession>
    <name>A4S774_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421222.1">
        <property type="nucleotide sequence ID" value="XM_001421185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S774"/>
    <dbReference type="GeneID" id="5005339"/>
    <dbReference type="Gramene" id="ABO99515">
        <property type="protein sequence ID" value="ABO99515"/>
        <property type="gene ID" value="OSTLU_18023"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18023"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_627548_0_0_1"/>
    <dbReference type="OMA" id="DAPFYAN"/>
    <dbReference type="OrthoDB" id="47172at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="196"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="369" mass="41813" checksum="FFC1D07D4D9520AD" modified="2007-05-15" version="1">MDYETLRRRAAEAAFDETSTTPEYRGFLNHARRCVDGSGKIDWGSVTRVGGLAGSREVRRARGVDPRDVEAACLRGEGEPLIVEDGGKDWAKWDFETLQNEIGDFEVLCNDRAPARRREIDGSKQRSHLIPFRAYADYVRKRDGVAGTVFDDRRTPFYANGMRVFSECKRADALSRAFPRPYFTHECDNTETLLMATTNELGSILKFDSEIALRMRDSVSKSLDKMFVGPRGALTRLHYDAGDAHGWLGQVEGRKLFVFYPPSASPMLYPIEDSHASVDPLEPDYDRFPLFREAQSRARVCVLNPGEVVLCPRRWWHYAVALDTSVTVMRNWYNVNTNAQALVEQICSTIKQTVDNRAKGSVPRNEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7T6</accession>
    <name>A4S7T6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421510.1">
        <property type="nucleotide sequence ID" value="XM_001421473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7T6"/>
    <dbReference type="GeneID" id="5005414"/>
    <dbReference type="Gramene" id="ABO99803">
        <property type="protein sequence ID" value="ABO99803"/>
        <property type="gene ID" value="OSTLU_27611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27611"/>
    <dbReference type="HOGENOM" id="CLU_3017632_0_0_1"/>
    <dbReference type="OrthoDB" id="541556at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="56" mass="5845" checksum="A54779E277F93B3E" modified="2007-05-15" version="1">MHREPVVMWSCAIGGLGMALPAIVPRELVETFSRDGKATRAVPSAAAVAKALRPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S870</accession>
    <name>A4S870_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase 1</fullName>
            <ecNumber evidence="2">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Bisphosphate 3'-nucleotidase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Inositol-polyphosphate 1-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_27745</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="2"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421575.1">
        <property type="nucleotide sequence ID" value="XM_001421538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S870"/>
    <dbReference type="STRING" id="436017.A4S870"/>
    <dbReference type="GeneID" id="5005613"/>
    <dbReference type="Gramene" id="ABO99868">
        <property type="protein sequence ID" value="ABO99868"/>
        <property type="gene ID" value="OSTLU_27745"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27745"/>
    <dbReference type="eggNOG" id="KOG3099">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_393540_0_0_1"/>
    <dbReference type="OMA" id="LMSDACR"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050725">
        <property type="entry name" value="CysQ/Inositol_MonoPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028:SF5">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673130" description="3'(2'),5'-bisphosphate nucleotidase 1" evidence="7">
        <location>
            <begin position="27"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00040342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="850" mass="91071" checksum="EE484ED81B4D515C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S880</accession>
    <name>A4S880_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">60S ribosomal export protein NMD3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_3943</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMD3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421580.1">
        <property type="nucleotide sequence ID" value="XM_001421543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S880"/>
    <dbReference type="STRING" id="436017.A4S880"/>
    <dbReference type="GeneID" id="5005618"/>
    <dbReference type="Gramene" id="ABO99873">
        <property type="protein sequence ID" value="ABO99873"/>
        <property type="gene ID" value="OSTLU_3943"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3943"/>
    <dbReference type="eggNOG" id="KOG2613">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027444_2_0_1"/>
    <dbReference type="OMA" id="VILVRKH"/>
    <dbReference type="OrthoDB" id="203821at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007029">
        <property type="term" value="P:endoplasmic reticulum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009834">
        <property type="term" value="P:plant-type secondary cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048899">
        <property type="entry name" value="NMD_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048898">
        <property type="entry name" value="OB_NMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21193">
        <property type="entry name" value="NMD_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21192">
        <property type="entry name" value="OB_NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="9">
        <location>
            <begin position="4"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 SH3" evidence="11">
        <location>
            <begin position="236"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 OB-fold" evidence="10">
        <location>
            <begin position="300"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="454"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="470"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="507" mass="58129" checksum="38B8E727768196D8" modified="2007-05-15" version="1" fragment="single">SVLCCLCAIPMHPNPSGMCVECVRTQVDITEGISKNCVVTYCSQCERYLQPPKHWIRADLESKELLTFCIKRIKGLQKVKLVDAGFVWTEPHSKRLKTKLTIQKEVLNGAILQQTFVTEFVVEWRMCDACARSAANSDQWNACVQVRQKVEHKRTFLFLEQMILKHGMERDAIGIKSQPDGLDFYYGHRSHGLRFVDFLGSVVATRSRGDKQLVSHDANSNTYNYRFTFFVEIVPVCKEDLVVIPFKLSKEFGSVGPVMLCTRVSNSLQFTDPVTMRQIWIDQEKYWRQPFRAAATAKQMIEYVILDVEVDQSTRQGKLCMADVEVARSSDFGVNDTTFFVKTHLGNILQAGDTALGYDLTNLQIVDPEMEKYSGKHQGVVPDVFLVKKSYAESRRRRRERGVARNWRLQRMQVEEDEETQQRSRGSADRMAQDEELFYQELEEDEETRAQVQIFKDENAINANVTAAAGDDDDDDDDAPEVPIEELLDELTLLQRQADDEDDENDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8B9</accession>
    <name>A4S8B9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NIPSNAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_89274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NipSnap family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421594.1">
        <property type="nucleotide sequence ID" value="XM_001421557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8B9"/>
    <dbReference type="STRING" id="436017.A4S8B9"/>
    <dbReference type="GeneID" id="5005632"/>
    <dbReference type="Gramene" id="ABO99887">
        <property type="protein sequence ID" value="ABO99887"/>
        <property type="gene ID" value="OSTLU_89274"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89274"/>
    <dbReference type="eggNOG" id="KOG2883">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090841_0_0_1"/>
    <dbReference type="OMA" id="WYESADH"/>
    <dbReference type="OrthoDB" id="10262843at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051557">
        <property type="entry name" value="NipSnap_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017">
        <property type="entry name" value="NIPSNAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017:SF17">
        <property type="entry name" value="PROTEIN NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="2">
        <location>
            <begin position="38"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="NIPSNAP" evidence="2">
        <location>
            <begin position="197"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="30405" checksum="E728BDAA37D97782" modified="2007-05-15" version="1">MFRAALRRASTHASLNARVRGAFRALATSATQKTGGIYEVRTYDIEPSRLDEYLAMCADSANERKKVTNEGFVGFFVTELGGDAHEVTHVYRYDDYDARDDARNAMKRSETWTAFLKASKPMVRRQKSEIFLEATKATASAGMEANDVLRRAREGNGGRADGVFEWRRYQLELGYNPIPKLVDALAKGLPSKLASDRDGRGELVWMGYSDVGKLNQFVELWRYDCYQDHIKAREAARSADAWRAAINEIAPMVQMFDTQLMRPAAASPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8D8</accession>
    <name>A4S8D8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Co-chaperonin 10, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CPN10</name>
        <name evidence="4" type="ORF">OSTLU_27813</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421602.1">
        <property type="nucleotide sequence ID" value="XM_001421565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8D8"/>
    <dbReference type="STRING" id="436017.A4S8D8"/>
    <dbReference type="GeneID" id="5005689"/>
    <dbReference type="Gramene" id="ABO99895">
        <property type="protein sequence ID" value="ABO99895"/>
        <property type="gene ID" value="OSTLU_27813"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27813"/>
    <dbReference type="eggNOG" id="KOG1641">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132825_0_2_1"/>
    <dbReference type="OMA" id="EDFLIMR"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="93" mass="9718" checksum="2C53A9984D7027B8" modified="2007-05-15" version="1">MDRVLVERIAPATKSVGGVLLPESMTGNTMNEAKVIAAGPGRRTMSGELVPLEIKVGDVVALPEFGGAAVNAGDGSGKEYFIYREEEIVGVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8S2</accession>
    <name>A4S8S2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_5819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421939.1">
        <property type="nucleotide sequence ID" value="XM_001421902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8S2"/>
    <dbReference type="STRING" id="436017.A4S8S2"/>
    <dbReference type="GeneID" id="5005967"/>
    <dbReference type="Gramene" id="ABP00233">
        <property type="protein sequence ID" value="ABP00233"/>
        <property type="gene ID" value="OSTLU_5819"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5819"/>
    <dbReference type="eggNOG" id="KOG1429">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_1"/>
    <dbReference type="OMA" id="GPRMPRD"/>
    <dbReference type="OrthoDB" id="10058185at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF13">
        <property type="entry name" value="UDP-D-APIOSE_UDP-D-XYLOSE SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="34121" checksum="48C9CB2E6CD5C7D0" modified="2007-05-15" version="1" fragment="single">LVTGGAGFIGSELVKQLLAIGLRVRVLDDLSTGSRARLAFAAEKQKEGKFALVEGDIRQYKNVKSAMANVAYVFHLAAVSKVKPTLDASKHDIVYACVEANVKGTENVLRATRERDDELLAAKKRRVRFVYTGSSTYYGNQPTPFDEERTHLRTTTTPYATTKAQGEDLARLYYSMYGVEAVITRLFMVYGPDEPAEGEQAVVTGRFFASAIAGEALEIEGDGTQFRDFIFVEDAARGLILAAMNDAATGRTFNIGSGTSTTVLDLAKMISSKHRFVDAREADLKGTLASTCLAKRVLGFEAKKLLTEYVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8T6</accession>
    <name>A4S8T6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UVR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_7291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421948.1">
        <property type="nucleotide sequence ID" value="XM_001421911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8T6"/>
    <dbReference type="GeneID" id="5005976"/>
    <dbReference type="KEGG" id="olu:OSTLU_7291"/>
    <dbReference type="eggNOG" id="ENOG502QPVH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084893_3_1_1"/>
    <dbReference type="OMA" id="HANDSWG"/>
    <dbReference type="OrthoDB" id="2335338at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34957">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34957:SF1">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UVR" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="143" mass="15495" checksum="8539B384C02E1B68" modified="2007-05-15" version="1" fragment="single">LRTAIRDEDYEEAARLRDLIDSISRDAARAVQDANEGFYRAFRDASVSAMRAVWAEGAHVQCLHPGSAVVSGARDVLESWEIIFASMPDGGADVQCADVRVHAGDGWGFATCVERVSGGASLAATNVFERQLDGSWRMVLHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8W1</accession>
    <name>A4S8W1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27987</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="436017.A4S8W1"/>
    <dbReference type="GeneID" id="5006121"/>
    <dbReference type="Gramene" id="ABP00250">
        <property type="protein sequence ID" value="ABP00250"/>
        <property type="gene ID" value="OSTLU_27987"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27987"/>
    <dbReference type="eggNOG" id="KOG0929">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_279824_0_0_1"/>
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    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
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        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="4">
        <location>
            <begin position="371"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="324"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="1125" mass="120018" checksum="A58F986CE5DE7D3C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S978</accession>
    <name>A4S978_OSTLU</name>
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        <recommendedName>
            <fullName evidence="1">Vacuolar fusion protein MON1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_18543</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in membrane trafficking through the secretory apparatus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MON1/SAND family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="5005918"/>
    <dbReference type="Gramene" id="ABP00309">
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        <property type="gene ID" value="OSTLU_18543"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG0997">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014574_2_0_1"/>
    <dbReference type="OMA" id="QQPFNAK"/>
    <dbReference type="OrthoDB" id="272411at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043970">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fuz_longin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="34"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 third Longin" evidence="4">
        <location>
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            <end position="473"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="481" mass="52117" checksum="909A9F05A2D87CBF" modified="2007-05-15" version="1">MTRARDARAPRAWTAAHKRAREHDEHDDWRRRRRHVLAFTSAGKPAWTRYGSTHGVSGLCATLQALGAVSASAMGGELEGAEVGGRRLARRASGAMTYATSSDRGESAATLEKHLEWVERGVKMLVTNAGLETALAKNAKFDVGRALATATRADEVLGQLARNLSWETCYVFDTYTAVRVRAEVRETVARAMVEAMKTVTKPFACVAFGDDGRVGAYAKPRGHRPTTIAASDLIVLMNFLRVVSRCEGDEDSFTRVCLPEFNPDGFMRAYTARLRARDGDAAGDEGQPVKSTRASSGSIGICIITASADAMEECRAARDALEKRLNDDGALAQMVAAAGESMSIAKLPSEALGGFQDASEPLLHFVYNRPARHQHVSSAFSPSLNGADVKAITRAYASTYTSMKETEGVVDASGPGPKFIGAAQRVRYERRARFSVLACVGGDFEIYLTLKPSTTTTTAVALCNRLCVWLRVHEPELFVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S998</accession>
    <name>A4S998_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GPR180/TMEM145 transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421899.1">
        <property type="nucleotide sequence ID" value="XM_001421862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S998"/>
    <dbReference type="GeneID" id="5005928"/>
    <dbReference type="Gramene" id="ABP00193">
        <property type="protein sequence ID" value="ABP00193"/>
        <property type="gene ID" value="OSTLU_93877"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93877"/>
    <dbReference type="eggNOG" id="ENOG502S82Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015819_0_0_1"/>
    <dbReference type="OMA" id="YHALEHP"/>
    <dbReference type="OrthoDB" id="496528at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019236">
        <property type="term" value="P:response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047831">
        <property type="entry name" value="GPR180/TMEM145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019336">
        <property type="entry name" value="GPR180/TMEM145_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23252">
        <property type="entry name" value="INTIMAL THICKNESS RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23252:SF24">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10192">
        <property type="entry name" value="GPR180-TMEM145_TM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="GPR180/TMEM145 transmembrane" evidence="2">
        <location>
            <begin position="259"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="GPR180/TMEM145 transmembrane" evidence="2">
        <location>
            <begin position="431"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="596" mass="65185" checksum="1A10F667301E1FFE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9D4</accession>
    <name>A4S9D4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421915.1">
        <property type="nucleotide sequence ID" value="XM_001421878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9D4"/>
    <dbReference type="GeneID" id="5005944"/>
    <dbReference type="Gramene" id="ABP00209">
        <property type="protein sequence ID" value="ABP00209"/>
        <property type="gene ID" value="OSTLU_93889"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93889"/>
    <dbReference type="eggNOG" id="ENOG502SYVX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1410913_0_0_1"/>
    <dbReference type="OMA" id="VCIACER"/>
    <dbReference type="OrthoDB" id="497638at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="20710" checksum="A6EA9BB52AED8892" modified="2007-05-15" version="1">MSAAPRRAPDPPALRARARSTRHRDARCRAAVVRRTGEDEPTQTPGVVRRAFAVDLGGPTPAAVALAFPDATDAVCFELTRPLGVVFEQRLSGATTEIFVDEVVENGAAAKAGVERGDVLRLCTAVFEVSAPVDVTTWLNPPAKRKVKAYYECDAKPFDSVMDALASHGVQIDTPNGKEDVKFVGLVLQRARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA34</accession>
    <name>A4SA34_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422276.1">
        <property type="nucleotide sequence ID" value="XM_001422239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA34"/>
    <dbReference type="GeneID" id="5006333"/>
    <dbReference type="Gramene" id="ABP00593">
        <property type="protein sequence ID" value="ABP00593"/>
        <property type="gene ID" value="OSTLU_28413"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28413"/>
    <dbReference type="HOGENOM" id="CLU_343689_0_0_1"/>
    <dbReference type="OMA" id="RVANWIF"/>
    <dbReference type="OrthoDB" id="10627827at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="824" mass="92650" checksum="6D20B1BE466197C8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA44</accession>
    <name>A4SA44_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_18783</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422315.1">
        <property type="nucleotide sequence ID" value="XM_001422278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA44"/>
    <dbReference type="GeneID" id="5006347"/>
    <dbReference type="Gramene" id="ABP00632">
        <property type="protein sequence ID" value="ABP00632"/>
        <property type="gene ID" value="OSTLU_18783"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18783"/>
    <dbReference type="HOGENOM" id="CLU_697166_0_0_1"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671953" description="Glycosyl transferase CAP10 domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="4">
        <location>
            <begin position="131"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="396" mass="45731" checksum="EDBD72490C00910F" modified="2007-05-15" version="1">MKTSARRLGLRVLLAFWLLKFVLSLQFITRGCERSVKYLSEMWMREDAWTHCRNCCGDVRERMLKFSSFGLGKDVACFTIHPEATSPSSYTFVARRREPLNRSYFKSALRFLRDVAVERRQNQGERSDVALRLLWVIDDDASMPRELKRELKSLNTFILAHSINVDCFTDESVVLAPNFHFIKRDGFKPLLRNLREREIPFDERKSDVFWRGSTSGMSTKCEIEEPARVDVNERVTACVELPRVRAVQSSINVPWLDVEITRRVQSCKGQTNVRISPHVSEQHWITHKGILEIDGNVDAWGNRWRMESGSVLFLVKSNFKHYYSDKLVDGVHYIGISGDLHDLVEKTKIVANTDGESLTKLRDITANARALMQEFTYERVVKGVSHRLNELALGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA66</accession>
    <name>A4SA66_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_25775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422326.1">
        <property type="nucleotide sequence ID" value="XM_001422289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA66"/>
    <dbReference type="GeneID" id="5006383"/>
    <dbReference type="Gramene" id="ABP00643">
        <property type="protein sequence ID" value="ABP00643"/>
        <property type="gene ID" value="OSTLU_25775"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25775"/>
    <dbReference type="HOGENOM" id="CLU_704741_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="392" mass="44601" checksum="B65791A6CFC91011" modified="2007-05-15" version="1">MSEAFLPTDLASFTRFKSGVQGDNVVEFIDLMVQSLNYRFTSSKINGRRKTEAVSVSIAADKLLRHYIDAKYKNANMDLCRITAIVASLDITFRDNIDLCKYVYNVMQDERDSNGLPGLPPANAENNRVTVKDYEKLHPDRTLVPLDVADQELADGVFDLSNVFPEQLKKLVSDMRASRATWSGITLLDRLLLELDPYSTIQTLVENRLNDIKYTGSGNMAEFLGNKRKLFTSLPNDSQVRLNNGLRLRRQVQSAFTINGNELTTSETIEFSGFTETILVMLLASPLSRTNVKKVCEELLSQQRDKLDFTKCTNKLVIADKLDQETSPKQLAVNNLKRKKFQPKGACFNCNRKGHRYWECKSPLRPDLQRRVDKFANKKPRGNESDPKEKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAD1</accession>
    <name>A4SAD1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28527</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422414.1">
        <property type="nucleotide sequence ID" value="XM_001422377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAD1"/>
    <dbReference type="STRING" id="436017.A4SAD1"/>
    <dbReference type="GeneID" id="5006424"/>
    <dbReference type="Gramene" id="ABP00731">
        <property type="protein sequence ID" value="ABP00731"/>
        <property type="gene ID" value="OSTLU_28527"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28527"/>
    <dbReference type="eggNOG" id="ENOG502QRYH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_516170_0_0_1"/>
    <dbReference type="OMA" id="LWHEYAP"/>
    <dbReference type="OrthoDB" id="2017169at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037494">
        <property type="entry name" value="RAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040858">
        <property type="entry name" value="Raf1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040781">
        <property type="entry name" value="Raf1_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041358">
        <property type="entry name" value="Raf1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35299">
        <property type="entry name" value="RUBISCO ACCUMULATION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35299:SF6">
        <property type="entry name" value="RUBISCO ACCUMULATION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18579">
        <property type="entry name" value="Raf1_HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18578">
        <property type="entry name" value="Raf1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18087">
        <property type="entry name" value="RuBisCo_chap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rubisco accumulation factor 1 helix turn helix" evidence="5">
        <location>
            <begin position="64"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Rubisco accumulation factor 1 alpha-helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Rubisco accumulation factor 1 C-terminal" evidence="3">
        <location>
            <begin position="277"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="449" mass="49272" checksum="9C0B417C9B37DACE" modified="2007-05-15" version="1">MDGFDADAVVVQRNPMSGGATTAGERKGPAGVIPKVGGELQGAYEPFKPPETYEAAKVSEDENDPERMMMLMRQRAGMWFTLAKFIRPLQAKGMTSTDIFDATGIEPKEQATWVVWLQCYASLKEGLDFDSTKLEYFHDEYRGAPNLSQIMYMPAATRAAAATFVVDNEFEETQTRELVKAYEIKSANVRTVAARDFNDTPGDILAYKLYRDILELQRYQGEEEALKIFERGMLYAVTEKAKARMATAVELFKRTKLGEGGSLANGESDEGAREAELQVVRLEEAEFLFIPMPVIGNLNKVTAAKVRTAGVLENTGNIFGVFSPQANTDWVALPKWDLLLQAVAPFALFIDDTSQTDIEGVKDKAEPGLLISDKSDNSPRFGQYYLVAKTSSLVLAGSNAAAETVSVMDGKDILQSERDGKKINTLARVLLCVRAPSRGGDGMSAEFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAG3</accession>
    <name>A4SAG3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Superoxide dismutase copper chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CCS</name>
        <name evidence="5" type="ORF">OSTLU_5907</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422381.1">
        <property type="nucleotide sequence ID" value="XM_001422344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAG3"/>
    <dbReference type="STRING" id="436017.A4SAG3"/>
    <dbReference type="GeneID" id="5006488"/>
    <dbReference type="Gramene" id="ABP00698">
        <property type="protein sequence ID" value="ABP00698"/>
        <property type="gene ID" value="OSTLU_5907"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5907"/>
    <dbReference type="eggNOG" id="KOG4656">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056632_0_2_1"/>
    <dbReference type="OMA" id="KNVWEER"/>
    <dbReference type="OrthoDB" id="666972at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016532">
        <property type="term" value="F:superoxide dismutase copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="225" mass="23201" checksum="CD2F0EA2AF4C22A8" modified="2007-05-15" version="1" fragment="single">ERALEFMVEMRCGGCAAKVTTACEALAGTTRVDASLGTNTVTVITRDAERTVREAIESAGYKARLIGQGRAERSAEDDDDFGEALAEALGTDARGTVRLVQVSEETILAEAALDGLSPGAHAIRVHEYGDLTRGMDSIGDVYGGEGGAGMIGIVVADENGSATMPSTMLSSELKAWDVIGRSVAVYAAADGDTTGAVCAVLARSAGVGANHKKLCQCDGTIIWEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAH8</accession>
    <name>A4SAH8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_3082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422435.1">
        <property type="nucleotide sequence ID" value="XM_001422398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAH8"/>
    <dbReference type="STRING" id="436017.A4SAH8"/>
    <dbReference type="GeneID" id="5006450"/>
    <dbReference type="Gramene" id="ABP00752">
        <property type="protein sequence ID" value="ABP00752"/>
        <property type="gene ID" value="OSTLU_3082"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3082"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="WKAADPP"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="10"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="30561" checksum="F4862AB5A8CDCF42" modified="2007-05-15" version="1" fragment="single">KDVTTITDAYEVLEKIGTGGFSTVARAREKATGRDVAIKVVDKSKYAPTDRSFDREVEVLSEIRHVNVVELYATYVTDRNVFMICELVQGGELLERVSRVGSFAEDEARSVIAQVLHAVAHMHARDIVHRDLKLENILLSDDGDRPTVKLIDFGLARFKPEGQTMRTVCGSPLYIAPEILELETSKDENEFYSPACDMWSVGVILFALLSGYSPFDHEDESVLYQNIRDGIYHLEPGVWDFISNPAKSLVAGLLETDANERLSAEQALAHEWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAJ0</accession>
    <name>A4SAJ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28587</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422396.1">
        <property type="nucleotide sequence ID" value="XM_001422359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAJ0"/>
    <dbReference type="STRING" id="436017.A4SAJ0"/>
    <dbReference type="GeneID" id="5006500"/>
    <dbReference type="Gramene" id="ABP00713">
        <property type="protein sequence ID" value="ABP00713"/>
        <property type="gene ID" value="OSTLU_28587"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28587"/>
    <dbReference type="eggNOG" id="KOG0941">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_837811_0_0_1"/>
    <dbReference type="OrthoDB" id="512027at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672275" description="RCC1-like domain-containing protein" evidence="4">
        <location>
            <begin position="35"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="40"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="41"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="97"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="147"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="199"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="332" mass="34299" checksum="5652EB479AA52738" modified="2007-05-15" version="1">MGARARARDARRTTRAFVAILALALRAATTPAAGTTLRWRKLHAWGENKLGEQGRGTATSAGTCAEGELPELGWDLNETVSRVVAGLDHAVALTARGEAYAWGSNRCGQLGTGDFIDALTPQRILSSHTIVDVAVGVEHTLALASDGALLAFGCNTRGALGIGSANLGRHATPQTVTSAETFTAIAAAGAHSVGLTEQGAVYTWGANNQGQLGLGGCVFPGGPGRDPCLNDVHTPTKVLVMNDGLVLPPIKLIAAGGGTLAGVARVPIGGHTVAVAKLDNSVYAWGDNFAGQLGVPQVYFNASSSAYFNNTPTYTPNKVRRIFLAQDAHLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB06</accession>
    <name>A4SB06_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SDG3503</name>
        <name evidence="9" type="ORF">OSTLU_19017</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422533.1">
        <property type="nucleotide sequence ID" value="XM_001422496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB06"/>
    <dbReference type="STRING" id="436017.A4SB06"/>
    <dbReference type="GeneID" id="5006750"/>
    <dbReference type="Gramene" id="ABP00850">
        <property type="protein sequence ID" value="ABP00850"/>
        <property type="gene ID" value="OSTLU_19017"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19017"/>
    <dbReference type="eggNOG" id="KOG1079">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_312251_0_0_1"/>
    <dbReference type="OMA" id="FAYSTHC"/>
    <dbReference type="OrthoDB" id="6141102at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046976">
        <property type="term" value="F:histone H3K27 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10519">
        <property type="entry name" value="SET_EZH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR045318">
        <property type="entry name" value="EZH1/2-like"/>
    </dbReference>
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        <property type="entry name" value="SET_dom"/>
    </dbReference>
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        <property type="entry name" value="SET_dom_sf"/>
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    <dbReference type="PANTHER" id="PTHR45747">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CXC" evidence="8">
        <location>
            <begin position="702"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="7">
        <location>
            <begin position="832"/>
            <end position="947"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="1"/>
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        </location>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="672"/>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="957"/>
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        </location>
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            <begin position="1"/>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
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        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS51633"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP00850.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="980" mass="109269" checksum="E2F91435C6FBFC37" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB34</accession>
    <name>A4SB34_OSTLU</name>
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        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SDG3522</name>
        <name evidence="2" type="ORF">OSTLU_89730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
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    </dbReference>
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        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="78"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="484" mass="52656" checksum="0A25AE02F261FE19" modified="2007-05-15" version="1">MRDARDDDFLDWMRARGVTRDDARCAVRGDGDRGRFVECARATLAVGTTLATIPKSACLTTATSALGAIEGARGSGVVGLCVAVAHERSLGAKSTFAAYLKTLPAREALPSTFAADDEARRALRGTTVEGMLGADERAIADDYHAFAREMKERFARRGVKMPTLEEFRDAATLVASRAFFVDDALGQGLVPFADLFNHKGGSDGAHFNVVGCDDADADALTLVTCRTAKRGEELFNSFGDDHDNTVLLYKYGFVERDNRVATSSFGFGLLRDAGDISFESVHSWMTESYDGVDELEVDANGAMSRPLLALLRIASFEFLRDVDSGDDESHSDDVDYDTSIGVLLERTMAGDESEAEILASVDDYVVLALFRGRFNAYLDTKDEDRCDDDVSSLLRDVAREIKRCADLANDASGVRQQFGSGISGVAAAYHVRADELGLLMKAIIRAFDFGDDEETNEDVPDTKKPKLVEVVPAYAPTIYIKPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBF4</accession>
    <name>A4SBF4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_43635</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422607.1">
        <property type="nucleotide sequence ID" value="XM_001422570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBF4"/>
    <dbReference type="STRING" id="436017.A4SBF4"/>
    <dbReference type="GeneID" id="5006824"/>
    <dbReference type="Gramene" id="ABP00924">
        <property type="protein sequence ID" value="ABP00924"/>
        <property type="gene ID" value="OSTLU_43635"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43635"/>
    <dbReference type="eggNOG" id="KOG0495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007010_0_0_1"/>
    <dbReference type="OMA" id="DGWAWYY"/>
    <dbReference type="OrthoDB" id="440128at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080188">
        <property type="term" value="P:gene silencing by siRNA-directed DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000636">
        <property type="term" value="P:positive regulation of primary miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000256">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000384">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="8">
        <location>
            <begin position="21"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Suppressor of forked" evidence="7">
        <location>
            <begin position="294"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="847" mass="94092" checksum="250DCD053CFF778A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQH6</accession>
    <name>A4RQH6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MOP(MATE) family transporter: multidrug efflux</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_3441</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415734.1">
        <property type="nucleotide sequence ID" value="XM_001415697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQH6"/>
    <dbReference type="STRING" id="436017.A4RQH6"/>
    <dbReference type="GeneID" id="4999839"/>
    <dbReference type="Gramene" id="ABO94026">
        <property type="protein sequence ID" value="ABO94026"/>
        <property type="gene ID" value="OSTLU_3441"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3441"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_1_0_1"/>
    <dbReference type="OMA" id="WPTEIAR"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="415" mass="43287" checksum="5F61A88F1447BFBE" modified="2007-05-15" version="1" fragment="single">AELAGAALASTIANVTGNAVVVGLVSALVTLGGQAYGQGRGGEAWAWAQRALACCAATATATAIGWRFVEGGLSAWHFDAAIARSCAAYLRGLRPGLFAYAANACAQAWLQAQGSTRPIACAGVAATALHAPACLCFRRMGFGAVGPAYATSVSTSLVFAANATYARLRRNRNGWTMFDREGLVLFLKLGVPGVLLMSEWWASEFIVLAAGKLRNPSVAISAMSIYQATNAFAFMVAVGFGAATATRVSNEVGAKDASRAKLAASVALRLIVVVEVAVSATVYLSRERWGAAFTSDHDVRALVSKLMVPLAFYVFFDAVCCVSTSVLRGAGRQAFATPIVLFAYYVVGLPLSAWLAYKGYGAMGLAIGGVVGTATHAGIMTRVALCIDWPTEIARSKHIRGASAFDDDDDLASRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQL5</accession>
    <name>A4RQL5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415752.1">
        <property type="nucleotide sequence ID" value="XM_001415715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQL5"/>
    <dbReference type="GeneID" id="4999416"/>
    <dbReference type="Gramene" id="ABO94044">
        <property type="protein sequence ID" value="ABO94044"/>
        <property type="gene ID" value="OSTLU_92072"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92072"/>
    <dbReference type="HOGENOM" id="CLU_1060007_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="263" mass="29079" checksum="138BCC679BD04AED" modified="2007-05-15" version="1" fragment="single">VRAIVGATTRIQTRAPPRANHRTAPLHGARAVTSVKRQSMSNRFQPPPRIARARSPRTDNDNSNRASREDSPREAAGQSRSRSRSPARASVLSLKRDQMLPFLRKLRPTFVFTNDRALLNLCGGGLNGATRPCRARAEVFNPLGLSVSCSVSATQLARFLHVLVHTPLAVAGLLLAAKSLVERSQRLREEREAREAWRVVEVEPAIPSDMGVEHALAMSIPLENDRLADDDEDEDEVSMAPSDWSFISDEFQDDASDSEVIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQP2</accession>
    <name>A4RQP2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_13638</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>prephenate + H(+) = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-phenylalanine from L-arogenate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415769.1">
        <property type="nucleotide sequence ID" value="XM_001415732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQP2"/>
    <dbReference type="STRING" id="436017.A4RQP2"/>
    <dbReference type="GeneID" id="4999771"/>
    <dbReference type="Gramene" id="ABO94061">
        <property type="protein sequence ID" value="ABO94061"/>
        <property type="gene ID" value="OSTLU_13638"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13638"/>
    <dbReference type="eggNOG" id="KOG2797">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035008_4_2_1"/>
    <dbReference type="OMA" id="PLMIYRE"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00344"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047769">
        <property type="term" value="F:arogenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13631">
        <property type="entry name" value="PBP2_Ct-PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000031">
        <property type="entry name" value="Arogenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000012">
        <property type="entry name" value="Prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008865">
        <property type="entry name" value="PRK11898.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="64"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="254"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="37971" checksum="DFEA88018E490592" modified="2007-05-15" version="1">MRTTSRARVAPSVRSRATRARGRAASRASVQSTSRAVRGVVARGRVVARASVDPTVFVASSDLRVAYQGVPGAYSEGAALAAYENCETVPKEQFDDVYAATEAQEVDRAVLPFENSLGGSIHRNYDLILTHKLHVVGEVYYRVNHCLLALPGQRVADLTRAQSHPQALAQCEGYLTNLKMVREAVDDTAGAAKAIAEAGAKGVAAVASRRAAELYGLEVYDEGIQDDKSNVTRFLALSREPIPAMQTDVPYKTSIAVSLKEEPGALFKALACFSLRDINMTKIESRPMRTNPVTSAGARQSMQFTYLFYIDFEANMADENMQNALRHLQESATFLRVLGSYPRDCSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR22</accession>
    <name>A4RR22_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Suppressor of forked domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_28863</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415828.1">
        <property type="nucleotide sequence ID" value="XM_001415791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR22"/>
    <dbReference type="STRING" id="436017.A4RR22"/>
    <dbReference type="GeneID" id="5000039"/>
    <dbReference type="Gramene" id="ABO94120">
        <property type="protein sequence ID" value="ABO94120"/>
        <property type="gene ID" value="OSTLU_28863"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28863"/>
    <dbReference type="eggNOG" id="KOG1972">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007550_1_0_1"/>
    <dbReference type="OMA" id="AYRNNTE"/>
    <dbReference type="OrthoDB" id="297219at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902369">
        <property type="term" value="P:negative regulation of RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="897" mass="101650" checksum="27D2F69FAC92256F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRA7</accession>
    <name>A4RRA7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_39514</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415866.1">
        <property type="nucleotide sequence ID" value="XM_001415829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRA7"/>
    <dbReference type="STRING" id="436017.A4RRA7"/>
    <dbReference type="MEROPS" id="T01.013"/>
    <dbReference type="GeneID" id="4999590"/>
    <dbReference type="Gramene" id="ABO94158">
        <property type="protein sequence ID" value="ABO94158"/>
        <property type="gene ID" value="OSTLU_39514"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39514"/>
    <dbReference type="eggNOG" id="KOG0174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_5_2_1"/>
    <dbReference type="OMA" id="CMDSQVK"/>
    <dbReference type="OrthoDB" id="7854943at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="246" mass="26015" checksum="09CB310AF4E4E930" modified="2007-05-15" version="1">MGLDARDADASEAPHTGTTIVACEYAGGVVLGADSRVSTGIYVSNRASDKMCALNDRTIMCRSGSAADTEALAGYVRNIVSQHEMELDEIADVKTVATIANQIGYQNKGANRGRGLSAYTIVGGWDKRRGSQVYACTAGGNMIKERWTTDGSGSTYIWGFLDSGWREGMTREECEAFVAKAIALAMSVDGSSGGCIRLNAVDASGIHRTFIQGSDVPPVLGELSQRRGRPEIARHGHQGASGGMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRB7</accession>
    <name>A4RRB7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_40307</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415545.1">
        <property type="nucleotide sequence ID" value="XM_001415508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRB7"/>
    <dbReference type="STRING" id="436017.A4RRB7"/>
    <dbReference type="GeneID" id="4999778"/>
    <dbReference type="Gramene" id="ABO93837">
        <property type="protein sequence ID" value="ABO93837"/>
        <property type="gene ID" value="OSTLU_40307"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40307"/>
    <dbReference type="eggNOG" id="KOG2104">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131642_0_0_1"/>
    <dbReference type="OMA" id="QFVEYYY"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000005">
        <property type="entry name" value="Nuclear transport factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="3">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="127" mass="14194" checksum="AC77FF4E995DF969" modified="2007-05-15" version="1" fragment="single">AQAFAEHYYNTFDTDRSQLGPLYNDTYSMLNFEHSVDRPGQFKGSAAIVEKLRTLPFQQVKHQVVTLDTQPSPNGGVVVMVCGNLLIDSEQQPQKFSQCFQLMPTEAAGLAPGSYFIFNDVFRLNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRF9</accession>
    <name>A4RRF9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415563.1">
        <property type="nucleotide sequence ID" value="XM_001415526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRF9"/>
    <dbReference type="GeneID" id="5000024"/>
    <dbReference type="Gramene" id="ABO93855">
        <property type="protein sequence ID" value="ABO93855"/>
        <property type="gene ID" value="OSTLU_92160"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92160"/>
    <dbReference type="HOGENOM" id="CLU_1392245_0_0_1"/>
    <dbReference type="OMA" id="ACRIEAN"/>
    <dbReference type="OrthoDB" id="10574688at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="21242" checksum="F1D68A57D073EEA8" modified="2007-05-15" version="1">MRTRARARSVGVAVAASVALLAGRARGDARARLEGTRDDAVAMRVAAFAPCEETNARTRVEMCFEHDIASGDAACAIGEGTIRRARDGTEVGDSCGAMEIADGRVVVRLRTGERSCAVREGDAFRIEAYYECASDGRLFPYSTLLLGEVVALADSAIYLAEAAHELEQAVETQDEEREHEEDDRATSFTIYWPASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRI3</accession>
    <name>A4RRI3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_39628</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the mTERF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415907.1">
        <property type="nucleotide sequence ID" value="XM_001415870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRI3"/>
    <dbReference type="STRING" id="436017.A4RRI3"/>
    <dbReference type="GeneID" id="4999820"/>
    <dbReference type="Gramene" id="ABO94199">
        <property type="protein sequence ID" value="ABO94199"/>
        <property type="gene ID" value="OSTLU_39628"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39628"/>
    <dbReference type="eggNOG" id="KOG1267">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044529_0_0_1"/>
    <dbReference type="OMA" id="CQEMEAV"/>
    <dbReference type="OrthoDB" id="508936at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003690">
        <property type="entry name" value="MTERF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13068">
        <property type="entry name" value="CGI-12 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13068:SF112">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02536">
        <property type="entry name" value="mTERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00733">
        <property type="entry name" value="Mterf"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="365" mass="42404" checksum="BAD3A031266AA01C" modified="2007-05-15" version="1">MVSYLISLGLKTADLEKVVVNCAELLNRPVPRVITRVEYLQSELGLEKKNLRQIVNKDPRILLQRNRHSIPRCRYLTKIGVPQEKLADVLGKQPSILHLSVQKGLMPRVQYLKQEVGILAEDIPLLIQRSPAVLTFSIENQIQPRVEFLRDLGISKDNVVKMITRHPQMLHYSFENLEEKLRFLGEIGMNDSETALTVTRLSQFFSLSVEDSLRPKFKYLTNELGGSKDTCVKYPAYFSLSLDQRIRPRHTFLEQFDLAPDPFPMKLLSVKDEDFVVRASKSIAEFEAYKEEMVPIFAAQTAREKTLREVSNSAEQQRMLLERKRIEFIRTTHEETVRKREYSERVAKARQSLRLLKGRSQHRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRJ9</accession>
    <name>A4RRJ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein transport protein Sec61 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_29044</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415914.1">
        <property type="nucleotide sequence ID" value="XM_001415877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRJ9"/>
    <dbReference type="STRING" id="436017.A4RRJ9"/>
    <dbReference type="GeneID" id="4999863"/>
    <dbReference type="Gramene" id="ABO94206">
        <property type="protein sequence ID" value="ABO94206"/>
        <property type="gene ID" value="OSTLU_29044"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29044"/>
    <dbReference type="eggNOG" id="KOG3457">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133423_3_1_1"/>
    <dbReference type="OMA" id="FRKNASC"/>
    <dbReference type="OrthoDB" id="5401193at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="7988" checksum="8D20913237909F37" modified="2007-05-15" version="1">MSGSVRRRANAGNSGEGNVRRPPQGSGSLLRFYTDESPGLKITPVVVLGMSVCFIGFVTMLHAIAKISAYTSSKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRR7</accession>
    <name>A4RRR7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_23942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415617.1">
        <property type="nucleotide sequence ID" value="XM_001415580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRR7"/>
    <dbReference type="STRING" id="436017.A4RRR7"/>
    <dbReference type="GeneID" id="5000000"/>
    <dbReference type="Gramene" id="ABO93909">
        <property type="protein sequence ID" value="ABO93909"/>
        <property type="gene ID" value="OSTLU_23942"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_23942"/>
    <dbReference type="eggNOG" id="ENOG502QPTC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069011_0_0_1"/>
    <dbReference type="OMA" id="LESRCFM"/>
    <dbReference type="OrthoDB" id="498322at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47426">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASES (NAT) SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47426:SF3">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="157"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="346" mass="37340" checksum="B06FEC01CE0C72EF" modified="2007-05-15" version="1">MASRAVSIDARARGDAMASRATRGATRDGARRATRGTQTTTTRRRAMTTTRCDGLARTGRGGATRDASTSTMMGAGAGARGGVARRALADRPTREAAEDEDARATGASRVKSRGGVDVVVATNDFAFEIAANLRATAFYDDLAERHEMPFPPRFTPTFHREFAQRERKALRERTTRRVGPALESRCFMADCEGLGLVGCLDVSVREGPCASQINGVCVPEGASYAYVDNVAVDAAARRRGSAKLMMECASDWVEERGITEIWTHVHCDNVGARRLYHAYGFRAPSGSHPEQGLPNYFNGERLKGLILMRAPVPLVYEARVDAVCGCGACFARVDECICIKPAVAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRU4</accession>
    <name>A4RRU4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_40267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415962.1">
        <property type="nucleotide sequence ID" value="XM_001415925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRU4"/>
    <dbReference type="STRING" id="436017.A4RRU4"/>
    <dbReference type="GeneID" id="4999519"/>
    <dbReference type="Gramene" id="ABO94254">
        <property type="protein sequence ID" value="ABO94254"/>
        <property type="gene ID" value="OSTLU_40267"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40267"/>
    <dbReference type="eggNOG" id="KOG1260">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027389_3_0_1"/>
    <dbReference type="OMA" id="QFVICAR"/>
    <dbReference type="OrthoDB" id="1923844at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905:SF2">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13714">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="34460" checksum="653E15CE421684C9" modified="2007-05-15" version="1">MSLAAAPGASSRVAHRARRDARCRASDGASVVAPHAKVLRDLLRSPRIVQAPCAHDALSARLIERAGFSAAFMSGFCVSASRLALPDTGLISYGEMVDVGRTCNDATSASFPIVGDGDDGYGNAMNAKRTVRGYAKAGFAGILIEDQVAPKACGHTKNRRVVSREEATTRVRAACDARDEDGSGIVVFARSDSRSAVDLDEALWRAAAFADVGADALFVDALRSKEEMRAFCKVAPGVPKMANMLEGGGSTPICTPQELEDMGFSIVAYPLSLLAVSVNAMERALREIKLEGYPRDETLPTFARLQESVGFPEYYADDARYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS41</accession>
    <name>A4RS41_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_001415977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS41"/>
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    <dbReference type="Gramene" id="ABO94306">
        <property type="protein sequence ID" value="ABO94306"/>
        <property type="gene ID" value="OSTLU_29236"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29236"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="629492at2759"/>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="540" mass="60180" checksum="01340078A116BA03" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSA2</accession>
    <name>A4RSA2_OSTLU</name>
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        <submittedName>
            <fullName evidence="13">Dhx57-like DEXH-box helicase, probable</fullName>
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        <name evidence="13" type="primary">Dhx57</name>
        <name evidence="13" type="ORF">OSTLU_119781</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DExH box helicase family.</text>
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        <property type="protein sequence ID" value="ABO94577.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="ABO94577"/>
        <property type="gene ID" value="OSTLU_119781"/>
    </dbReference>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_4_0_1"/>
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    <dbReference type="OrthoDB" id="5600252at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000526">
        <property type="entry name" value="DExH-box ATP-dependent RNA helicase DExH3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
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    </dbReference>
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        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
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    </dbReference>
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        <property type="entry name" value="HA2_WH"/>
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    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24385">
        <property type="entry name" value="DSRM_DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
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        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="651"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="1020"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="555"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="887"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="223"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="898"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="924"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1545" mass="169625" checksum="6F58F66CA08ABC54" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSU0</accession>
    <name>A4RSU0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyribonucleoside kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DrnK</name>
        <name evidence="2" type="ORF">OSTLU_119574</name>
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    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416431.1">
        <property type="nucleotide sequence ID" value="XM_001416394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSU0"/>
    <dbReference type="STRING" id="436017.A4RSU0"/>
    <dbReference type="GeneID" id="5000158"/>
    <dbReference type="Gramene" id="ABO94724">
        <property type="protein sequence ID" value="ABO94724"/>
        <property type="gene ID" value="OSTLU_119574"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119574"/>
    <dbReference type="eggNOG" id="KOG4235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030466_1_1_1"/>
    <dbReference type="OMA" id="PARWAFT"/>
    <dbReference type="OrthoDB" id="567086at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050566">
        <property type="entry name" value="Deoxyribonucleoside_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10513:SF35">
        <property type="entry name" value="DEOXYADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10513">
        <property type="entry name" value="DEOXYNUCLEOSIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deoxynucleoside kinase" evidence="1">
        <location>
            <begin position="51"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="303" mass="35453" checksum="6096867E3E6C33EA" modified="2007-05-15" version="1">MPCRLTPTRQFERLVCLRNVSQTTRRRGHRQVLRMYRCSRQALDTAYKVSLCVEGNISSGKSTFLSEVLSSASRLEDLVYTVPEPVQSWQSVPRKSASNPPHNLLKEFYTNPERYAYVFQNYVFMTRYLQERQSAGTSKLLRITERSVFSDRNVFVESVHEQGWLSELEADLYNAWLYPMINALPSLIPDGFIYLRVEPDVCMERLQRRARGEELNITLEYLESLHYKHEKWLLQDVRALTVGKKHQETLTIGFVTDHMCSQFKKKPVLILEFGHDVDFSSDDKTVEQLGKKVRAFYDYISDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT77</accession>
    <name>A4RT77_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S14, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS14</name>
        <name evidence="6" type="ORF">OSTLU_29967</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416360.1">
        <property type="nucleotide sequence ID" value="XM_001416323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT77"/>
    <dbReference type="STRING" id="436017.A4RT77"/>
    <dbReference type="GeneID" id="5000465"/>
    <dbReference type="Gramene" id="ABO94653">
        <property type="protein sequence ID" value="ABO94653"/>
        <property type="gene ID" value="OSTLU_29967"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29967"/>
    <dbReference type="eggNOG" id="KOG0407">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072439_6_0_1"/>
    <dbReference type="OMA" id="ETICHES"/>
    <dbReference type="OrthoDB" id="1677536at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="139" mass="14804" checksum="921718C364530F27" modified="2007-05-15" version="1">MATYVGPNAREGELVFGVAHIYASFNDTFVHVTDLSGKETLSRCTGGMKVKADRDESSPYAAMLAAQDVAARCKELGITALHIKMRATGGNKTKSPGPGGQSALRALSRSGLKIGRIEDVTPTPTDSTRRKGGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT83</accession>
    <name>A4RT83_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416118.1">
        <property type="nucleotide sequence ID" value="XM_001416081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT83"/>
    <dbReference type="GeneID" id="5000289"/>
    <dbReference type="KEGG" id="olu:OSTLU_92288"/>
    <dbReference type="HOGENOM" id="CLU_835194_0_0_1"/>
    <dbReference type="OrthoDB" id="10530267at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="333" mass="36838" checksum="78AF8BBE695E16BC" modified="2007-05-15" version="1" fragment="single">LEEKLVETRDENKLLRRDLVERDGENSELHRAVAERDGAQRFLKTQLADWNQRLYARAEGSDSQLAGTTTSASEGSATELRTRLDQVEIELGAKTGAVIALERRVKDQDKALERARAEIEKMREKLFARETTDVRATAPKQRSKYVEDAENTAAQVMETLRATRDRHAEKRSRDARAARRVGGPKSAQSRPATKKRERAPPSSVVIDANAPYQPPRANDDEDEDDDGDDDSEYEEIDVPIKRTTKKGMSKKKSIAPAAAKENAATDAAPANDGPRMPLGMLQMPKLGAKKDKGAVDDVAQKKRRLNRQSAIPEALPSLMFGVADGDFQVAPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT89</accession>
    <name>A4RT89_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="5">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">OSTLU_12211</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="5"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416116.1">
        <property type="nucleotide sequence ID" value="XM_001416079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT89"/>
    <dbReference type="STRING" id="436017.A4RT89"/>
    <dbReference type="GeneID" id="5000137"/>
    <dbReference type="Gramene" id="ABO94408">
        <property type="protein sequence ID" value="ABO94408"/>
        <property type="gene ID" value="OSTLU_12211"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12211"/>
    <dbReference type="eggNOG" id="KOG0614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_73_2_1"/>
    <dbReference type="OMA" id="YSYFDRY"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd05572">
        <property type="entry name" value="STKc_cGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000210">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035014">
        <property type="entry name" value="STKc_cGK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0140">cGMP</keyword>
    <keyword evidence="15" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="22">
        <location>
            <begin position="6"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="22">
        <location>
            <begin position="120"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="21">
        <location>
            <begin position="217"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="23">
        <location>
            <begin position="473"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ABO94408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="528" mass="58912" checksum="BDA80D26B097349E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTT8</accession>
    <name>A4RTT8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416553.1">
        <property type="nucleotide sequence ID" value="XM_001416516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTT8"/>
    <dbReference type="GeneID" id="5000846"/>
    <dbReference type="Gramene" id="ABO94846">
        <property type="protein sequence ID" value="ABO94846"/>
        <property type="gene ID" value="OSTLU_30380"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30380"/>
    <dbReference type="HOGENOM" id="CLU_1013149_0_0_1"/>
    <dbReference type="OMA" id="HAGDWIN"/>
    <dbReference type="OrthoDB" id="498061at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="264" mass="27945" checksum="4FFCCAE1CE2CC8A9" modified="2007-05-15" version="1">MSSARVVVAARRGVASRRGARTTTRGATPNDARSDELVRASARAAADAKAAVTRRNVRATVEARKRADEDREAAAREEAAAEKRARAEARAAAIGGRRPFHRKAGPIAAAGAACLAATAGCFEATVHAGDWINALAVPGDALVGASGAPAKSGLLTLTIGVGLTVTSTLAFSTAILFALAFQEGKGVIKNEPIVYYRCDGADPTCCVNGPHNKGYHERFVYMNHGRGFETRRAGCMQRHLRVSRGCSALKPLIVYPKDEDWGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUE3</accession>
    <name>A4RUE3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_4561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416657.1">
        <property type="nucleotide sequence ID" value="XM_001416620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUE3"/>
    <dbReference type="STRING" id="436017.A4RUE3"/>
    <dbReference type="GeneID" id="5000581"/>
    <dbReference type="Gramene" id="ABO94950">
        <property type="protein sequence ID" value="ABO94950"/>
        <property type="gene ID" value="OSTLU_4561"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4561"/>
    <dbReference type="eggNOG" id="KOG1113">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2044125_0_0_1"/>
    <dbReference type="OMA" id="HIEMFTS"/>
    <dbReference type="OrthoDB" id="496483at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="13512" checksum="1477B9606A01231E" modified="2007-05-15" version="1" fragment="single">RRLRYERTLAKIPVFADLGSYERAMVVKQAKRFSFKPGEKIIRQGEVADKFYVILKGSAVSTKSDGDVDHVAPGSKIPPDRIMRNFSQGQYFGELALLTGQPRLATIVANDSLEVLAIDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUJ2</accession>
    <name>A4RUJ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA 4-demethylwyosine synthase (AdoMet-dependent)</fullName>
            <ecNumber evidence="4">4.1.3.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_12352</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:36347"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10165"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="EC" id="4.1.3.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TYW1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="4"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416681.1">
        <property type="nucleotide sequence ID" value="XM_001416644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUJ2"/>
    <dbReference type="STRING" id="436017.A4RUJ2"/>
    <dbReference type="GeneID" id="5000815"/>
    <dbReference type="Gramene" id="ABO94974">
        <property type="protein sequence ID" value="ABO94974"/>
        <property type="gene ID" value="OSTLU_12352"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12352"/>
    <dbReference type="eggNOG" id="KOG1160">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007952_2_0_1"/>
    <dbReference type="OMA" id="NVPYHKD"/>
    <dbReference type="OrthoDB" id="271553at2759"/>
    <dbReference type="UniPathway" id="UPA00375"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000196">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00284">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01071">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="16">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="17">
        <location>
            <begin position="177"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="70"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="486"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO94974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="515" mass="57879" checksum="41D38793CEF1D594" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUK1</accession>
    <name>A4RUK1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416973.1">
        <property type="nucleotide sequence ID" value="XM_001416936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUK1"/>
    <dbReference type="GeneID" id="5000566"/>
    <dbReference type="Gramene" id="ABO95266">
        <property type="protein sequence ID" value="ABO95266"/>
        <property type="gene ID" value="OSTLU_30649"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30649"/>
    <dbReference type="HOGENOM" id="CLU_054114_0_0_1"/>
    <dbReference type="OMA" id="LELEWQY"/>
    <dbReference type="OrthoDB" id="497909at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="381" mass="42144" checksum="396E06E653FEEB90" modified="2007-05-15" version="1">MRGDDARRRRVRRESSASGTAGERDDREGNAASERDRGGDRASTSARSSKEGSSLERQIAVTQRLREGFERDPFLRELGREAFAANVEYDNDVHAVRGLDEYRELMEHFSDATKSALKGFKFVTRRASSIEPGVLLIQWTAVWEGARFGKKFSNLLLGSMHEGAVRRIVEGEYGEKVAPGYPATATVADGKEPRTDLNFRLFGRTTYKVNRDGLIASRLDRIDFRTDPEPGSQSGDDFFPETPEEEEAEWEQLAEETAVNMFYNTLSPPGKNETSWFLDVLIELEWQSFQRQMGDTTSVLSKQEYVSVIYAVLASAIAAPIFIIVGLTALLLSPDQAGDPDSLDAAMTMGSDLAKLDTGANGSPVWGADVFLDLYKGKIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUL5</accession>
    <name>A4RUL5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GHMP kinase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_34345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416692.1">
        <property type="nucleotide sequence ID" value="XM_001416655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUL5"/>
    <dbReference type="STRING" id="436017.A4RUL5"/>
    <dbReference type="GeneID" id="5000996"/>
    <dbReference type="Gramene" id="ABO94985">
        <property type="protein sequence ID" value="ABO94985"/>
        <property type="gene ID" value="OSTLU_34345"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34345"/>
    <dbReference type="eggNOG" id="ENOG502QPZV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_791831_0_0_1"/>
    <dbReference type="OMA" id="MDQACAY"/>
    <dbReference type="OrthoDB" id="188923at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF7">
        <property type="entry name" value="GALACTOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457">
        <property type="entry name" value="MEVALONATE KINASE/GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="4">
        <location>
            <begin position="85"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="38269" checksum="B3F0BECDA63FEB3F" modified="2007-05-15" version="1">MPRVFVPGRVCLLGEHSDWAGARAARDGPGACVVVGTREGVSARCDVGEGPRFRVVGADGDAFECDVSVDDALEREASSGGYWSYVAGTALEVLRRFPRCRERGLVVETLETTLPTRKGLSSSACVCVLVARCFGVAYELDLELKDEMELAYRGEAVHTPSKCGAMDQACAYGSERVVALTFDGEDVDVRACEVDGEIHIVVCDLAASKSTVRILADLQGAFDRGDEALRSALGARNRALVAEGLDAIKRGDARALGAVYTRAQTTFDEAAIHICPSELTAPRLRETLAAVAHDVPETVFGAKGVGSQGDGAAQFVAVSEAAAKTLRQYLHDFSGGRFKVFDVVLRDEERHARTSTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUQ9</accession>
    <name>A4RUQ9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416714.1">
        <property type="nucleotide sequence ID" value="XM_001416677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUQ9"/>
    <dbReference type="GeneID" id="5000979"/>
    <dbReference type="Gramene" id="ABO95007">
        <property type="protein sequence ID" value="ABO95007"/>
        <property type="gene ID" value="OSTLU_30707"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30707"/>
    <dbReference type="HOGENOM" id="CLU_2999861_0_0_1"/>
    <dbReference type="OrthoDB" id="10343435at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="57" mass="6472" checksum="BF96E8FB3BD9A86A" modified="2007-05-15" version="1">MDDGRVNRFVERESGAKRSERAVVGFWQTFAARASEARRKHFDGRKTVSSKDGTKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUR7</accession>
    <name>A4RUR7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416717.1">
        <property type="nucleotide sequence ID" value="XM_001416680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUR7"/>
    <dbReference type="STRING" id="436017.A4RUR7"/>
    <dbReference type="GeneID" id="5000792"/>
    <dbReference type="Gramene" id="ABO95010">
        <property type="protein sequence ID" value="ABO95010"/>
        <property type="gene ID" value="OSTLU_30715"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30715"/>
    <dbReference type="eggNOG" id="ENOG502RZWK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1404556_0_0_1"/>
    <dbReference type="OrthoDB" id="10517221at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36342">
        <property type="entry name" value="PTB DOMAIN ENGULFMENT ADAPTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36342:SF1">
        <property type="entry name" value="PTB DOMAIN ENGULFMENT ADAPTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="20965" checksum="70E186A51511B0A7" modified="2007-05-15" version="1">MFGERGGPAGTSHWMVLVRHAGDEHAAVYDFLPKTPKSPFTAAKLLSGNSVEGVVRSRRLAGVPGRRCCRVGGTRAGLGGRIAIEAAIAAFHERWDADALRLGTNDCRNHSVELARWLTCDYGYGIEVSSDAKGTLTCRRTATPATEEEDEDEGSVEIVPVDVERVSRDVATNASSKDRKNKKQKKKKSSGGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV41</accession>
    <name>A4RV41_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417072.1">
        <property type="nucleotide sequence ID" value="XM_001417035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV41"/>
    <dbReference type="GeneID" id="5000574"/>
    <dbReference type="Gramene" id="ABO95365">
        <property type="protein sequence ID" value="ABO95365"/>
        <property type="gene ID" value="OSTLU_30839"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30839"/>
    <dbReference type="HOGENOM" id="CLU_732349_0_0_1"/>
    <dbReference type="OrthoDB" id="10658466at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="378" mass="39616" checksum="776104CAFA1B64F2" modified="2007-05-15" version="1">MNPAYESGASGAARGTTGAKGANEGKFDATSLLALLGEQYDLKRTTSGNTRLEAKPVAKRSAYETARDAARDEMDENAKPTATGGAKRTAPEYEFVMIGREETKTKASASKVVRFNANENSIVGDSGSPAMATTAATETRAAPWSKAVVERESSVSYAASRGGGSKPGGGIPSYGGSAGASRGGDGSVARAIAQYRAASTRRSDDDSAVRDSSQENSVEGGEAGGKIVGEMPVPVTVDATPAGALPAARASEDALRASQLARQRFQAVSNAAYVSKELDRFTNERRNAAQSVGQSSRGARPTRSTGSQNTHDSLRVQYQQGHGGDVADLMMHRRGDLLRRLGSWLNARFKSVTGFKVAPTFPLDKRIERFVLGSGLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV78</accession>
    <name>A4RV78_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BAH-PHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">EBP3501</name>
        <name evidence="7" type="ORF">OSTLU_34069</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416795.1">
        <property type="nucleotide sequence ID" value="XM_001416758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV78"/>
    <dbReference type="STRING" id="436017.A4RV78"/>
    <dbReference type="GeneID" id="5001028"/>
    <dbReference type="Gramene" id="ABO95088">
        <property type="protein sequence ID" value="ABO95088"/>
        <property type="gene ID" value="OSTLU_34069"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34069"/>
    <dbReference type="eggNOG" id="KOG1633">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1886">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085193_0_0_1"/>
    <dbReference type="OMA" id="NMENCDS"/>
    <dbReference type="OrthoDB" id="494865at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46364">
        <property type="entry name" value="OS08G0421900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BAH" evidence="6">
        <location>
            <begin position="13"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="21341" checksum="447E1F430B1FEA47" modified="2007-05-15" version="1">MTGEVARVVIGGDVFQVNDAVLVKAPGANERYVGRIVSVAVENGAVKARLCWYYRPQETRGGRKRFHGVKELFSSDHYDWVSVNTIDAKCEVWSLREYQELEAVTEFDFYARFLYRSSRGEFRPEKVPVFCKCAEPYNPDRFMVECDQCNDWFHPECVNETKSSASQLDVWRCPDCRLSKITGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVC1</accession>
    <name>A4RVC1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_9586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417113.1">
        <property type="nucleotide sequence ID" value="XM_001417076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVC1"/>
    <dbReference type="GeneID" id="5001027"/>
    <dbReference type="Gramene" id="ABO95406">
        <property type="protein sequence ID" value="ABO95406"/>
        <property type="gene ID" value="OSTLU_9586"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9586"/>
    <dbReference type="HOGENOM" id="CLU_2801937_0_0_1"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="70" mass="7793" checksum="03DA954AB28B04D8" modified="2007-05-15" version="1" fragment="single">RMGIVKLATDGSVWVHSPIELDERTRAVVDALGVVRHVVSPNYEHLKYAQQWKDAYPGATLYACPGLKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVI5</accession>
    <name>A4RVI5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ABCG) family transporter: White protein-like protein (ABCG)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_14894</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417145.1">
        <property type="nucleotide sequence ID" value="XM_001417108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVI5"/>
    <dbReference type="GeneID" id="5001371"/>
    <dbReference type="Gramene" id="ABO95438">
        <property type="protein sequence ID" value="ABO95438"/>
        <property type="gene ID" value="OSTLU_14894"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14894"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_57_9_1"/>
    <dbReference type="OMA" id="WWKQFWL"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF41">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="556" mass="59656" checksum="18A6814C9A4EFE1E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVL8</accession>
    <name>A4RVL8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF948 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417164.1">
        <property type="nucleotide sequence ID" value="XM_001417127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVL8"/>
    <dbReference type="STRING" id="436017.A4RVL8"/>
    <dbReference type="GeneID" id="5001384"/>
    <dbReference type="Gramene" id="ABO95457">
        <property type="protein sequence ID" value="ABO95457"/>
        <property type="gene ID" value="OSTLU_31020"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31020"/>
    <dbReference type="eggNOG" id="ENOG502QUNI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1158030_0_0_1"/>
    <dbReference type="OMA" id="TMDEIAY"/>
    <dbReference type="OrthoDB" id="1923031at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33825">
        <property type="entry name" value="CHITINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33825:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="25344" checksum="9100EBE85D00CF51" modified="2007-05-15" version="1">MTRDARATREVVSQLGARRDASALAPRTAHGATVAYVRQPIEAKNVEFMTPNFAVYALCGVGCLLGSALSAVLLSLIPTLRSARRTMDEIAYLAASVREEVPDTLAAVRVSGLELTDVMEEVGELTADVGGGLRSAGRGITASVNTAQMVGRYAAAAVPEVRRRATPIVGSVKTGTVRVLEERADMEPYSGPIISNTAKSAKKGVTAARNALKSADVARNVGRLYKTLRAPPARPKDMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVQ4</accession>
    <name>A4RVQ4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial GrpE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MGE1</name>
        <name evidence="5" type="ORF">OSTLU_14947</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417453.1">
        <property type="nucleotide sequence ID" value="XM_001417416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVQ4"/>
    <dbReference type="STRING" id="436017.A4RVQ4"/>
    <dbReference type="GeneID" id="5001201"/>
    <dbReference type="Gramene" id="ABO95746">
        <property type="protein sequence ID" value="ABO95746"/>
        <property type="gene ID" value="OSTLU_14947"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14947"/>
    <dbReference type="eggNOG" id="KOG3003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057217_0_2_1"/>
    <dbReference type="OMA" id="QHELICH"/>
    <dbReference type="OrthoDB" id="201635at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="26431" checksum="5B53306CFD252179" modified="2007-05-15" version="1">MDDRAMGRREMSARGGWETPARERCAWTRALGKEGFGGGARARGFASEGKPEDETTAEDESGEDAEGDGEGEDEVSRLRGELEEKDAKVADLTDRILRTMAEMENLRERTRRQAEDAKKFAIQGFCKDLLDVADNLDRAIATVTVDDDENDVEKVKTKLKSFHEGVVMTEKTLLSAFKKHGVTKFNPEGEEFDANSHMALFNVPIPEGSDAKAGTVAAVTKTGYSLHERVIRAAEVGVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVW3</accession>
    <name>A4RVW3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_49458</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417219.1">
        <property type="nucleotide sequence ID" value="XM_001417182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVW3"/>
    <dbReference type="STRING" id="436017.A4RVW3"/>
    <dbReference type="GeneID" id="5001322"/>
    <dbReference type="Gramene" id="ABO95512">
        <property type="protein sequence ID" value="ABO95512"/>
        <property type="gene ID" value="OSTLU_49458"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49458"/>
    <dbReference type="eggNOG" id="KOG1802">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_386571_0_0_1"/>
    <dbReference type="OMA" id="VDETASH"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF518">
        <property type="entry name" value="RNA HELICASE NONSENSE MRNA REDUCING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="64"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="191"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="295"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="715" mass="78267" checksum="F61444DF3C7193B4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW09</accession>
    <name>A4RW09_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417243.1">
        <property type="nucleotide sequence ID" value="XM_001417206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW09"/>
    <dbReference type="STRING" id="436017.A4RW09"/>
    <dbReference type="GeneID" id="5001332"/>
    <dbReference type="Gramene" id="ABO95536">
        <property type="protein sequence ID" value="ABO95536"/>
        <property type="gene ID" value="OSTLU_31173"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31173"/>
    <dbReference type="HOGENOM" id="CLU_626120_0_0_1"/>
    <dbReference type="OMA" id="CQTHMAT"/>
    <dbReference type="OrthoDB" id="10513333at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672933" evidence="2">
        <location>
            <begin position="32"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="438" mass="48026" checksum="9265EAF65F313324" modified="2007-05-15" version="1">MDATTRRGSVGRLSSALALVGALAALACVAGLGGDRGVAARAGLGSHHGHKKEILEGSTKNCVNAAADNAAGTFQMETSKCEDLSTPGCVGHRSMCRFCQTHMATNRNHDWPVCPATVCAENDVHGCKSESGKKMTKRELAWDILRQHVLDHNSMVAGIKIGKCHGNSQDHGLGRYQYSDSQCLRSGLPGCLGAGAACRFCNVKNAKKAGNEWPTCPMAVCDKYDVKSKYCAKLTQYHVPPETPPKDWDEKSLPDTMSVELDEDDEDADSLKLKSVKSHHQHKHKHSEDDDDDDDDDIDAKPVSKHSKHSDSAGLGEDEGEDDDEYYSKESTIPVEADDDDDDDDDDEEDEEDYEDDEDEDEDEDKSHVKKHHHHHSKVKLGNQAALDDQAIVHTHKNEQSVKQTHAASDLDSLVFEEIDVEAISSERGKKRSSRGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWB7</accession>
    <name>A4RWB7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WHEP-TRS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_31282</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417299.1">
        <property type="nucleotide sequence ID" value="XM_001417262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWB7"/>
    <dbReference type="GeneID" id="5001516"/>
    <dbReference type="Gramene" id="ABO95592">
        <property type="protein sequence ID" value="ABO95592"/>
        <property type="gene ID" value="OSTLU_31282"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31282"/>
    <dbReference type="eggNOG" id="ENOG502S2CN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_822299_0_0_1"/>
    <dbReference type="OMA" id="NTHRAYC"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="7">
        <location>
            <begin position="215"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="338" mass="36445" checksum="2002C54D137121A3" modified="2007-05-15" version="1">MHWRVGKGSESANGAGEATARGGKGSSKTTRSQRTNKSYKVYVSGRPTIDDVERASRGEKTKSMGVVEREAPYRLTRDEREAWERAKRRGGLETRSASRDGLARRRFPLVNTHRAYCDAVGMVFVCTEQDVGGGEDCVVVDVSTLRASEDGDARARLSELAIALGASAEDLCGDEEPLMAQMRYVAAMEGGFERTALVEVLEGDAEAEPAPSESEIAAARDAVSAAADRVREMKDSGKSNADDDVKAGVRCLLEAKAKLGAMEAAAEKTSAAANEAAEVDLEAELKRIEEAARRSLVELPIHGLPERYMRFKCPDRPTAKALSKAIAKEDLAPLLLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWD9</accession>
    <name>A4RWD9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417313.1">
        <property type="nucleotide sequence ID" value="XM_001417276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWD9"/>
    <dbReference type="GeneID" id="5001619"/>
    <dbReference type="Gramene" id="ABO95606">
        <property type="protein sequence ID" value="ABO95606"/>
        <property type="gene ID" value="OSTLU_31305"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31305"/>
    <dbReference type="HOGENOM" id="CLU_1799697_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="144" mass="17106" checksum="BFB038F36110F963" modified="2007-05-15" version="1">MRVVEKLAYRGATNRIVAYYDPARVVEMQRKWIETLMDEKVLLIERLRRARRIADENRESALAWRRAYVDCRANKNAFAEPKPIVAKPHDATSWSPAWSWYAHPRSKSTVKTVNVIRRFCPIVAELRLRRIVEWMARRLVSTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWF0</accession>
    <name>A4RWF0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417320.1">
        <property type="nucleotide sequence ID" value="XM_001417283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWF0"/>
    <dbReference type="STRING" id="436017.A4RWF0"/>
    <dbReference type="GeneID" id="5001235"/>
    <dbReference type="Gramene" id="ABO95613">
        <property type="protein sequence ID" value="ABO95613"/>
        <property type="gene ID" value="OSTLU_31315"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31315"/>
    <dbReference type="eggNOG" id="ENOG502QSMU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_790827_0_0_1"/>
    <dbReference type="OrthoDB" id="10475615at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36337">
        <property type="entry name" value="OBSCURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36337:SF1">
        <property type="entry name" value="OBSCURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="38928" checksum="1DF42BBE1C698C1C" modified="2007-05-15" version="1">MNAHFIAEAVSRDDGLDPRQSLPMLMEFSRNVYDTAQELAASECAGWTDTLDNSVVRAARANIYDFALITLKNALRGRLEAHVGDAMFVLSHLEFARSTSLEYAQVLGALATLLNSLPSSSDAPAAMAFLASLPELAGDAWRGDKILGARMHLILRLLPFALSKFTTPRIIVDVCPYVRRCCDHEAKHVVKAAHVAYVGIFHARPELNGQLFPDYLRMSLERYPASTPLEPLVAAVGLVTKFGEAGSELALFVARELSEKVKNMDAAPPTMSSEDPPVEPLRRLLFQLVTLVDFPLIPVIQDILEDAVLDSSDPFTRARRHETLAYTVMRCPDYARKPMMVDWVMQMNSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWI3</accession>
    <name>A4RWI3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417582.1">
        <property type="nucleotide sequence ID" value="XM_001417545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWI3"/>
    <dbReference type="GeneID" id="5001421"/>
    <dbReference type="Gramene" id="ABO95875">
        <property type="protein sequence ID" value="ABO95875"/>
        <property type="gene ID" value="OSTLU_31346"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31346"/>
    <dbReference type="HOGENOM" id="CLU_1201540_0_0_1"/>
    <dbReference type="OMA" id="MCAKYAG"/>
    <dbReference type="OrthoDB" id="496470at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="231" mass="25663" checksum="6153779D2FF6FEE4" modified="2007-05-15" version="1">MSTARASVFTPTARIARASRAHRARVAKPFAATAEAPANAALRQFPDAPAKIIEHDDVLGWAQLESKLIAACATNVGDSSVNARFQAAALLGATTTYDAVNELSVVEVYTQVYEGDLTTCSTIIDVHLRILCESMIDGDWERIGNCYKKFHDLPPQLKRQSLLATSAVAEAALLFTKEEYEYMVSFLQDMYESPDATEELKAEYEVNLEMVTAIDRFIDEMQKNKDERDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWX5</accession>
    <name>A4RWX5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_31491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417653.1">
        <property type="nucleotide sequence ID" value="XM_001417616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWX5"/>
    <dbReference type="GeneID" id="5002066"/>
    <dbReference type="Gramene" id="ABO95946">
        <property type="protein sequence ID" value="ABO95946"/>
        <property type="gene ID" value="OSTLU_31491"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31491"/>
    <dbReference type="eggNOG" id="KOG2458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035768_0_0_1"/>
    <dbReference type="OrthoDB" id="535029at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="4">
        <location>
            <begin position="271"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="531"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="549"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="559" mass="61861" checksum="B6CAE4F04B886360" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY99</accession>
    <name>A4RY99_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_31951</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418350.1">
        <property type="nucleotide sequence ID" value="XM_001418313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY99"/>
    <dbReference type="STRING" id="436017.A4RY99"/>
    <dbReference type="GeneID" id="5002293"/>
    <dbReference type="Gramene" id="ABO96643">
        <property type="protein sequence ID" value="ABO96643"/>
        <property type="gene ID" value="OSTLU_31951"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31951"/>
    <dbReference type="HOGENOM" id="CLU_2444830_0_0_1"/>
    <dbReference type="OMA" id="GYFWQVV"/>
    <dbReference type="OrthoDB" id="261831at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="90" mass="10630" checksum="743F4F2414134E7F" modified="2007-05-15" version="1">MERENDRDIDRVSERASALKNITIDIHDEVGAQRRMLDEQSDDFARARDALRESARAFAQVVEQARRQGYFWQVVCLVFVFVFFARWAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYB5</accession>
    <name>A4RYB5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_31967</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418141.1">
        <property type="nucleotide sequence ID" value="XM_001418104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYB5"/>
    <dbReference type="STRING" id="436017.A4RYB5"/>
    <dbReference type="GeneID" id="5002234"/>
    <dbReference type="Gramene" id="ABO96434">
        <property type="protein sequence ID" value="ABO96434"/>
        <property type="gene ID" value="OSTLU_31967"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31967"/>
    <dbReference type="eggNOG" id="KOG0217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_3_0_1"/>
    <dbReference type="OMA" id="FMRKVGC"/>
    <dbReference type="OrthoDB" id="497591at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="769"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="958" mass="107302" checksum="EF2B37F282615B9C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYF4</accession>
    <name>A4RYF4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_32009</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418376.1">
        <property type="nucleotide sequence ID" value="XM_001418339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYF4"/>
    <dbReference type="GeneID" id="5002436"/>
    <dbReference type="Gramene" id="ABO96669">
        <property type="protein sequence ID" value="ABO96669"/>
        <property type="gene ID" value="OSTLU_32009"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32009"/>
    <dbReference type="HOGENOM" id="CLU_331332_0_0_1"/>
    <dbReference type="OMA" id="RATWALH"/>
    <dbReference type="OrthoDB" id="430205at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046977">
        <property type="entry name" value="RsmC/RlmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47816">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47816:SF4">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase small" evidence="4">
        <location>
            <begin position="688"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="865" mass="93492" checksum="8CA90C573359C9CC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYG1</accession>
    <name>A4RYG1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418382.1">
        <property type="nucleotide sequence ID" value="XM_001418345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYG1"/>
    <dbReference type="GeneID" id="5002259"/>
    <dbReference type="Gramene" id="ABO96675">
        <property type="protein sequence ID" value="ABO96675"/>
        <property type="gene ID" value="OSTLU_32017"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32017"/>
    <dbReference type="HOGENOM" id="CLU_595023_0_0_1"/>
    <dbReference type="OrthoDB" id="10486310at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="460" mass="49576" checksum="89779424D9EF7E6F" modified="2007-05-15" version="1">MASTAVESLESTALFERVADGSTATAEEFSTLAWAEASMSERRWVQNFARFAQDIVKSRFEAVLETYQPLRDIVTFWNVVMGESSEFERSGASVAANHMLGKIICGACVGVPNVGILGAAALAAHHREVNPELEVSKLKKSLIYADASKSFAAGTVLSIGGPLTAPLTMLPQLVMYFTIRMRLCLAIAIMGREDDDIAVLRPSLIAAALLCFFGSNAVDVISLRPTVEQFELEDLMNDLETADAFRGAEAEDLLDDDKPVKSLGEILNEKLTRLGDDAKERTNEAIRTVLESGSRAERSAQRDAAVASERIRVFVKAQGGSPGEANRAAEEAFAKALPVSLYERMSECVFTADNLPILVAELVPAVSSYLTIRAATTAMTCMLPESVAAAEQIAREAASEDQETIEQAPETWDESAKKTLVAAGESTKRAAVAVGEATQNAFSEINRSLSRMFSRSSKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYL9</accession>
    <name>A4RYL9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418187.1">
        <property type="nucleotide sequence ID" value="XM_001418150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYL9"/>
    <dbReference type="GeneID" id="5002169"/>
    <dbReference type="Gramene" id="ABO96480">
        <property type="protein sequence ID" value="ABO96480"/>
        <property type="gene ID" value="OSTLU_94472"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94472"/>
    <dbReference type="eggNOG" id="ENOG502S87T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_765904_0_0_1"/>
    <dbReference type="OMA" id="GFSICMG"/>
    <dbReference type="OrthoDB" id="46497at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052636">
        <property type="entry name" value="UDP-D-xylose:L-fucose_XylT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47032">
        <property type="entry name" value="UDP-D-XYLOSE:L-FUCOSE ALPHA-1,3-D-XYLOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47032:SF1">
        <property type="entry name" value="UDP-D-XYLOSE:L-FUCOSE ALPHA-1,3-D-XYLOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="1">
        <location>
            <begin position="113"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="362" mass="40459" checksum="58D8B58184EA5F37" modified="2007-05-15" version="1">MSADVERIGLVRGERVRRTDAENHGWRATKLALGAIAVLAAVCVGVGGRRGRAIGAAFGGLARLGVGADSADSAESWTHEDWRVVSFVDAEYEDIGKRWYHRLSNLGYKTHYLVALDDEVYDKLEKAKLRVLRAPGFTLEKGGDLSDFWRFRLTYLADEIKRGHNVLLSDVDVIFAHHYDPVVIFNKAGDEEVDIYHSLGAGWPHSAKKQWGFSICMGFSAFRATRATEQILEAAVKVCDHEAHCDDQVVMNELYMKYLQMSWTTNLAHGERKGISRNTMIPLVVKTLSNLVPRIDLKDMTPIKPSSKNVQCFGHTHHVDGGHWAVAPIIEKDGRAKVDVWDQLHDECFPATISALGAQWTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYX6</accession>
    <name>A4RYX6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418470.1">
        <property type="nucleotide sequence ID" value="XM_001418433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYX6"/>
    <dbReference type="STRING" id="436017.A4RYX6"/>
    <dbReference type="GeneID" id="5002489"/>
    <dbReference type="Gramene" id="ABO96763">
        <property type="protein sequence ID" value="ABO96763"/>
        <property type="gene ID" value="OSTLU_15788"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15788"/>
    <dbReference type="eggNOG" id="ENOG502R383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_572919_0_0_1"/>
    <dbReference type="OMA" id="CATADHE"/>
    <dbReference type="OrthoDB" id="10338668at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="477" mass="51638" checksum="272D0CA7F378B324" modified="2007-05-15" version="1">MERPASESLTTIAPLQLRFEDISVHSPGVFAKSDAMKTLREAPSGVGFRAALKELNQTEDSFAKILSQAREKALGNGDGDLERIKAHIKRLKFGTIELSTEQAFLKAVLESRPLPKETPTESEGFKALQQRLKNLTNENERRAEEMEREIASLGDEYETFRVEHRALTEVVEELEQLEAEAAAAAWEAQAGDASVSAADRAKSKEELQRELEALDAELREVNVKLSENQSGASELKAELAPDESAIDQINAQAKYLIGISKAAAREAEMSAQIAEAQEAVLEQTKLLVTLQGVEIMAIEENALVLKIHTHLPATPEFAMESAKPRGPSSTTHTVTLHLMKDSARLAGATLEPSDTPILDIIEESAGMPVLARALAEIRLRIAATAQRAEALAAAAARTALRWSSGESLVRAALPNGAVAVLDVPFEWPTRGANISLINVEMVPPQVAQLAVTRLMTKNLLCIGDALEATSEALKNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZA0</accession>
    <name>A4RZA0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_9544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418538.1">
        <property type="nucleotide sequence ID" value="XM_001418501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZA0"/>
    <dbReference type="STRING" id="436017.A4RZA0"/>
    <dbReference type="GeneID" id="5002535"/>
    <dbReference type="Gramene" id="ABO96831">
        <property type="protein sequence ID" value="ABO96831"/>
        <property type="gene ID" value="OSTLU_9544"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9544"/>
    <dbReference type="HOGENOM" id="CLU_093295_2_0_1"/>
    <dbReference type="OrthoDB" id="196633at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019634">
        <property type="entry name" value="Uncharacterised_Ycf49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33833">
        <property type="entry name" value="NUCLEOLAR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33833:SF3">
        <property type="entry name" value="YCF49-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10693">
        <property type="entry name" value="DUF2499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="9583" checksum="5E27E6EE05AEBF98" modified="2007-05-15" version="1" fragment="single">NALSLPTWAVHVSSVTEWALAMKYVAGHADRTGNASWRNLTVAMSPFLASGITACTFHAFYNPASINALVPLQALLTLMGNTGCAVAAYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZN0</accession>
    <name>A4RZN0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FBT family transporter: folate/pteridine</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_12682</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418597.1">
        <property type="nucleotide sequence ID" value="XM_001418560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZN0"/>
    <dbReference type="STRING" id="436017.A4RZN0"/>
    <dbReference type="GeneID" id="5002924"/>
    <dbReference type="Gramene" id="ABO96890">
        <property type="protein sequence ID" value="ABO96890"/>
        <property type="gene ID" value="OSTLU_12682"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12682"/>
    <dbReference type="eggNOG" id="ENOG502QPYM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018563_3_2_1"/>
    <dbReference type="OMA" id="HIEATMY"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015231">
        <property type="term" value="F:5-formyltetrahydrofolate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008517">
        <property type="term" value="F:folic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015350">
        <property type="term" value="F:methotrexate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd17484">
        <property type="entry name" value="MFS_FBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004324">
        <property type="entry name" value="FBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00788">
        <property type="entry name" value="fbt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="45891" checksum="7C3A2B0C7211E543" modified="2007-05-15" version="1">MSPEVYAIALVYFVQGVIGLSRLAKDFYLKDELRLGPSETAMILSISQAPWLIKPLWGFLSDSVPLFGYRRKSYLMACGAVGCLGWASMATWVDAPETALVAFTLGSLSIAFSDVLIDSIVVAKARGEEQGVSGSLQSLCWGFVAIGSIVSSYFSGSLIESYGTRFVFGATAVFPLMIAGASTLVQEKPIVETAQVSSEGVLSDFKAMSGKLFQVAKRRDIWAPAFFVFLWQATPSAGTAMFYFNTNELGFSPEFLGRVALVRAFCALGGVALYNGYLKRVPLKKMFLWTSILGTALGSTQLLLVSRMNLELGISDKVFALTDTAVLTVLGEVSFLPVLVLAAKICPEGVEATFFAALMSLFNAGGVTSEFLGAGLTKSLGVTADNFDNLFLLLSICLVTGLLPLAAINLIDEVKDDDADDVESAQKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZQ3</accession>
    <name>A4RZQ3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_32466</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RZQ3"/>
    <dbReference type="GeneID" id="5002630"/>
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        <property type="protein sequence ID" value="ABO97130"/>
        <property type="gene ID" value="OSTLU_32466"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32466"/>
    <dbReference type="eggNOG" id="ENOG502T2T8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1032049_0_0_1"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="134"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="183"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="27679" checksum="71A547B6FC55C9D4" modified="2007-05-15" version="1">MATQAMYAQQMMTTMTPEAMGAAYYERQNAALAAMGPHMMASYAAYVAYVQSQTYNVQAYAGMMGASPPFSGAYGTPAMGAAAYGGEATSARTGRGGGGAKKGGKGGRAGRKGGVTQSIRACKATVKASTNVKAQKQKICVNCKSTETPFWRKDKDGIGSLCNACGLYAAKNHAPRPALLWRRSGATGSENGGSDKTGSDKTTEAVPSSSGDAAENKSKQDGHTSLLKTSGSGDLTATTTTTTTTTTTDSDDARIAKQEAKLDGVGRGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZX7</accession>
    <name>A4RZX7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418877.1">
        <property type="nucleotide sequence ID" value="XM_001418840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZX7"/>
    <dbReference type="STRING" id="436017.A4RZX7"/>
    <dbReference type="GeneID" id="5002808"/>
    <dbReference type="Gramene" id="ABO97170">
        <property type="protein sequence ID" value="ABO97170"/>
        <property type="gene ID" value="OSTLU_32548"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32548"/>
    <dbReference type="eggNOG" id="KOG2184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2241127_0_0_1"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47423">
        <property type="entry name" value="G-PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47423:SF2">
        <property type="entry name" value="PROTEIN SQS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="56"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="105" mass="11119" checksum="E0296EAD02F34845" modified="2007-05-15" version="1">MEPNANGEPVVYPNRGARRAAEAQARDREFIEKARAKKRGTVVGAGHEYGAFEKHTTGFGSRMLAKMGFQGQGSGVGREGEGIAEPVTATTRGKRVGLGAFGAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S075</accession>
    <name>A4S075_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase RsuA/RluA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32641</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418694.1">
        <property type="nucleotide sequence ID" value="XM_001418657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S075"/>
    <dbReference type="STRING" id="436017.A4S075"/>
    <dbReference type="GeneID" id="5002977"/>
    <dbReference type="Gramene" id="ABO96987">
        <property type="protein sequence ID" value="ABO96987"/>
        <property type="gene ID" value="OSTLU_32641"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32641"/>
    <dbReference type="eggNOG" id="KOG1919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051745_0_0_1"/>
    <dbReference type="OMA" id="ACEVEFE"/>
    <dbReference type="OrthoDB" id="498383at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF44">
        <property type="entry name" value="RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="110"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="334" mass="35987" checksum="95A8BA89823A56B6" modified="2007-05-15" version="1">MAAAKARGDAATAFNAAISAYNRMGMSESCVALMEMMRDALDVAPDVVTYALCASALTREGRLRDAEATLERASEALRRGTRPNRKQKKRAKNDDEWSMVVLRDSDGIAAVVKPAGVLTHPVEGGGSELTLMDAALSRFDGQLSDLNGLDKRGIVSRLDKPTSGVVLLAKNNASHAELLTQFYQRCVVKQYCALLDGTLPASGSESTPLDGRSATSEYEVMETFIGPSWSYSLVRVEPKSGRKHQIRRHMALLGAPLVGDPLYRTARTKQINPNPPECVLKALSVGKPGTIFWLHASAVEYSGMPNGERIVVSAPLPSAFETLLASLRAGARDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0F1</accession>
    <name>A4S0F1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Digalactosyldiacylglycerol synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_46154</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418961.1">
        <property type="nucleotide sequence ID" value="XM_001418924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0F1"/>
    <dbReference type="STRING" id="436017.A4S0F1"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="GeneID" id="5002903"/>
    <dbReference type="Gramene" id="ABO97254">
        <property type="protein sequence ID" value="ABO97254"/>
        <property type="gene ID" value="OSTLU_46154"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_46154"/>
    <dbReference type="eggNOG" id="ENOG502QQ73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011647_1_0_1"/>
    <dbReference type="OMA" id="FHHGKKW"/>
    <dbReference type="OrthoDB" id="44480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009707">
        <property type="term" value="C:chloroplast outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046481">
        <property type="term" value="F:digalactosyldiacylglycerol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019375">
        <property type="term" value="P:galactolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01635">
        <property type="entry name" value="Glycosyltransferase_GTB-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044525">
        <property type="entry name" value="DGDG1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46132">
        <property type="entry name" value="DIGALACTOSYLDIACYLGLYCEROL SYNTHASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46132:SF1">
        <property type="entry name" value="DIGALACTOSYLDIACYLGLYCEROL SYNTHASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="48354" checksum="1CC0E32497607125" modified="2007-05-15" version="1" fragment="single">MVLKRMFSRGSLGDLNERRAKKRSRTNPKDLRAPGRKFVIVTTAALPWMTGTSVNPLLRAVYLANGDTTREVTLLVPWLARKDQRIVYPKRVEFKTPSEQEAYIMDWTKKRVGFAPKILIAWYPGRYATDKGSIVPVGDITLRVPKASRDVAILEEPEHLCWYHPGARWTSRFKHVVGIIHTNYLEYARREEDGERKEQILRWINHLTARCHTHKVIKLSDAVQEFARSITQNVHGVSNGFIDAGREKAKRIKKEGSGAFSRGAYFIGKCVWAKGYSELMHVVGDFNEKYAKSAKERLEMDVYGDGDDFADVKAAVAEKALPLSLLGRLDHANEKILDYKVFINPSLSDVVATTSAEALAMGKFVVCAEHPSNAFFATFPNCRTYSNMDEFAKCIREVTTSTPKPMTDDEIHRLTWEAATERLLDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0H9</accession>
    <name>A4S0H9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_32753</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418749.1">
        <property type="nucleotide sequence ID" value="XM_001418712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0H9"/>
    <dbReference type="STRING" id="436017.A4S0H9"/>
    <dbReference type="GeneID" id="5002885"/>
    <dbReference type="Gramene" id="ABO97042">
        <property type="protein sequence ID" value="ABO97042"/>
        <property type="gene ID" value="OSTLU_32753"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32753"/>
    <dbReference type="eggNOG" id="KOG1322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_14_4_1"/>
    <dbReference type="OMA" id="INSGMRQ"/>
    <dbReference type="OrthoDB" id="496137at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523:SF12">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE LARGE SUBUNIT 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25247">
        <property type="entry name" value="LbH_GLGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotidyl transferase" evidence="9">
        <location>
            <begin position="169"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="482" mass="52651" checksum="66E0D34999C1B6A9" modified="2007-05-15" version="1">MEALKDGGVGGRGTRKSREAASTRRDFRARDARCVVLAGGADETNPLTRGRARSAVHLGGAYRVIDFPLTNLINSGMRQVYVLTQYNSHSLVTHVNRAFPMEMFGNNNEGFVEVLPTSQTREHGETWSMGSADCVARHLTHGSLTKHSFDMRLEDECLQRHGSLEACAANQTDGITIVLAAEQLYTMDFNKLLEAHLKSEADVTVATCDQVTAENASRLGIMDVDEHTSSILSFIEKPSADQLLEFMQCSTENELLECKLNANMGVYVFNNSALEELLRDSKNPAEERHEFGRDIIPHAVNAGYDVRSYKHSGYWKPLRTLADIYEANISVATGGDAASLIDFDRLVYTKPNFLPPNTFYGSSLTERSIISDGCVIRDGAKIINSIVGPCTVIDKNVDLEGVVVVGRDEILKRSGGDKVADIGANTIIRKCMVDSDAVIGANVRILNEAGIQELDRTEDGYIISEGIVTILGGAVIPDGFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Q5</accession>
    <name>A4S0Q5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="gene ID" value="OSTLU_32827"/>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="39"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="36327" checksum="EB05F747E599D74C" modified="2007-05-15" version="1">MVAVFVLGAATLGTVVINVKRNAMKKMSGSMFEDEARRAAAAKERVDGIAKLLEEVNAKANAAEEKLEAAMREKNAIERVLEEMERTKANMKVENMELRDSVTVLKNDLNNATERHQLVVRKWRDELVTYREKSPQDFLAEVIGLVSDMDNEVTIEVIPPEAPRAAKVHEEVRLEECEWEYNPRLAVADSTRLLMLANSGRVVKKTREEKVKKVTGVKPVASPHRATTPTRAALGKLTNTGVQRAQGVAHKAARLVQANHVANTPPPKVATSDRSIEFGECLLFEKQLKSPVRAPKIGGGRAGVIGGFEAEDVMPLPSSPATIMDIAIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Y2</accession>
    <name>A4S0Y2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellar associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419056.1">
        <property type="nucleotide sequence ID" value="XM_001419019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Y2"/>
    <dbReference type="STRING" id="436017.A4S0Y2"/>
    <dbReference type="GeneID" id="5003391"/>
    <dbReference type="Gramene" id="ABO97349">
        <property type="protein sequence ID" value="ABO97349"/>
        <property type="gene ID" value="OSTLU_32907"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32907"/>
    <dbReference type="eggNOG" id="ENOG502RXMS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084072_0_0_1"/>
    <dbReference type="OMA" id="VHRNWTS"/>
    <dbReference type="OrthoDB" id="415460at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.50">
        <property type="entry name" value="Protein of unknown function (DUF3228), domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021610">
        <property type="entry name" value="DUF3228"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38666">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38666:SF2">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11539">
        <property type="entry name" value="DUF3228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="24004" checksum="89E58B94681FEAD5" modified="2007-05-15" version="1">MASTGDASTVTETFFLDDFAVRQWDDERYSGTRIAHDKADFVRKIQEAHESGKSPLVDGYAPFCKHVFVENFVGAKVGNVEITKSNEHLLKSGYSARSEAELAVLTRWFQASDVEAPEATHLDVILYSREQLELERAAVPSKSERPPLPNAPWGIISVKAQSEDYETPMQPITMMRNALGREQGGSGVPLEKDKYDASVAYWANHAPIVASEDGAAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S109</accession>
    <name>A4S109_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419070.1">
        <property type="nucleotide sequence ID" value="XM_001419033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S109"/>
    <dbReference type="GeneID" id="5003335"/>
    <dbReference type="Gramene" id="ABO97363">
        <property type="protein sequence ID" value="ABO97363"/>
        <property type="gene ID" value="OSTLU_16355"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16355"/>
    <dbReference type="HOGENOM" id="CLU_627551_0_0_1"/>
    <dbReference type="OMA" id="TSTIWIP"/>
    <dbReference type="OrthoDB" id="10674488at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="512" mass="55675" checksum="5A7003DF1309F612" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S123</accession>
    <name>A4S123_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419077.1">
        <property type="nucleotide sequence ID" value="XM_001419040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S123"/>
    <dbReference type="GeneID" id="5003342"/>
    <dbReference type="Gramene" id="ABO97370">
        <property type="protein sequence ID" value="ABO97370"/>
        <property type="gene ID" value="OSTLU_32949"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32949"/>
    <dbReference type="HOGENOM" id="CLU_2337412_0_0_1"/>
    <dbReference type="OrthoDB" id="5561579at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="98" mass="10798" checksum="DD1010BA95F53CFF" modified="2007-05-15" version="1">MEAYRNKFIATGKFAPLKHFMVGVFVLAFGLETYHHHKYHGEHDHGDEGHGDGAEAANGAAANSARERAALGSLDGAQMEVEELREKVKAMRETMMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S166</accession>
    <name>A4S166_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419098.1">
        <property type="nucleotide sequence ID" value="XM_001419061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S166"/>
    <dbReference type="STRING" id="436017.A4S166"/>
    <dbReference type="GeneID" id="5003435"/>
    <dbReference type="Gramene" id="ABO97391">
        <property type="protein sequence ID" value="ABO97391"/>
        <property type="gene ID" value="OSTLU_32990"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32990"/>
    <dbReference type="eggNOG" id="ENOG502S9F5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2150096_0_0_1"/>
    <dbReference type="OMA" id="SGAHAMI"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="21"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="112" mass="11691" checksum="B4C6C03CA15E1F88" modified="2007-05-15" version="1">MAHLDAPVRAPGDLTIEATKSVIGRQRSEAVNLPIEVPTVSGAHAMIDLVDGKVMVTDLTSTNGTFIDGEELLPGVPTQLVVGGEVIFGDEFLARFELVETADEGSGDDAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1B4</accession>
    <name>A4S1B4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_33039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419334.1">
        <property type="nucleotide sequence ID" value="XM_001419297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1B4"/>
    <dbReference type="STRING" id="436017.A4S1B4"/>
    <dbReference type="GeneID" id="5003287"/>
    <dbReference type="Gramene" id="ABO97627">
        <property type="protein sequence ID" value="ABO97627"/>
        <property type="gene ID" value="OSTLU_33039"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33039"/>
    <dbReference type="eggNOG" id="KOG0945">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057011_3_2_1"/>
    <dbReference type="OMA" id="WVFEESL"/>
    <dbReference type="OrthoDB" id="26719at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055066">
        <property type="entry name" value="AASDHPPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22624">
        <property type="entry name" value="AASDHPPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase N-terminal" evidence="4">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="129"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="35943" checksum="441DAB19EE45379B" modified="2007-05-15" version="1">MLDTADHLRLRWIVNSTTWRPGVDEFAFVLTILPTHEREEVTRFHRFEDRKRALLSRLMQRAAIKRACASAEDARWRDARVEALDVRRTKGSKPFHGARASVAGAPNFNYNVSHEGDYVVLASETHAVVGVDVAAPGQVRRVTGGGGAERDVGKLLETFSSVLTDRERASIAGVAARDGERAGEELFRKHWSLKEAHVKAIGVGLGMDLRRCEFDIDAARSTASVSVDGKSRNDWSFHMQAFPPIVDDAVNEDRHWITVSRGPVEDIVDADGEFTETTFSRRDFSKDEWSAILAAPAPSFELLTVGDLIPIDSKDAFEAAGGVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1B7</accession>
    <name>A4S1B7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_87987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419336.1">
        <property type="nucleotide sequence ID" value="XM_001419299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1B7"/>
    <dbReference type="STRING" id="436017.A4S1B7"/>
    <dbReference type="GeneID" id="5003288"/>
    <dbReference type="Gramene" id="ABO97629">
        <property type="protein sequence ID" value="ABO97629"/>
        <property type="gene ID" value="OSTLU_87987"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87987"/>
    <dbReference type="eggNOG" id="ENOG502QTWP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_892523_0_0_1"/>
    <dbReference type="OMA" id="PQNPFIT"/>
    <dbReference type="OrthoDB" id="2019920at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36761">
        <property type="entry name" value="ORF03 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36761:SF2">
        <property type="entry name" value="ORF03 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="34495" checksum="52101A255185EDBC" modified="2007-05-15" version="1">MPALARAVLPNLAHARRARRSRTAQRSSSERRADDAIIASKPVVVSSNPANNASKALLQEVRRALIPTGADAAKVLKATQRFQEAFEAGEDFETTVAKALGYSSLAEAPEAQRKYAEKIAEKLESNARTLRGEIESATKMYDSGVYAYGRGMYDDAVKWFKAAEDETSETSLLGGRIQIYKALALDAYGQGDKALEIYKYLESVHPEKSIRKQAEELRFILEAPKMEIAANERVEVPLLRDPDSFAPYSDKWSTGAKASASGGRKKREKTLEEQYGQEAREKFDYEKLRLGLQICGGVAIACGVAWYSTTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1I9</accession>
    <name>A4S1I9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED10</name>
        <name evidence="7" type="ORF">OSTLU_33116</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419375.1">
        <property type="nucleotide sequence ID" value="XM_001419338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1I9"/>
    <dbReference type="GeneID" id="5003441"/>
    <dbReference type="Gramene" id="ABO97668">
        <property type="protein sequence ID" value="ABO97668"/>
        <property type="gene ID" value="OSTLU_33116"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33116"/>
    <dbReference type="HOGENOM" id="CLU_1963287_0_0_1"/>
    <dbReference type="OMA" id="WELHQLE"/>
    <dbReference type="OrthoDB" id="337270at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019145">
        <property type="entry name" value="Mediator_Med10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09748">
        <property type="entry name" value="Med10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="128" mass="13883" checksum="149962E579795A33" modified="2007-05-15" version="1">MSAAPAPSALGQALEKAIWELHQLEKIIELGAPSDERVIEKIEDFAQTLPALREAAEKCDDVEIPVELLRDVDQGKKPMGFMINQILAAGTVNETVKGKANVYREFAEALKGKLDGGEKKAGAKRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1L3</accession>
    <name>A4S1L3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419170.1">
        <property type="nucleotide sequence ID" value="XM_001419133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1L3"/>
    <dbReference type="GeneID" id="5003223"/>
    <dbReference type="Gramene" id="ABO97463">
        <property type="protein sequence ID" value="ABO97463"/>
        <property type="gene ID" value="OSTLU_33139"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33139"/>
    <dbReference type="HOGENOM" id="CLU_2188373_0_0_1"/>
    <dbReference type="OrthoDB" id="10618278at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="109" mass="11677" checksum="39744121E159B4E4" modified="2007-05-15" version="1">MVSSTSTSTSFWGRCTIGGLVLAVLMTLSASSLTHWPTVAFAFANPTTFAINPSAADAEAKIAVVLEIGRRLAKPCVRYLAAWFALRSRWRLMWATFAASCAISGVTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1W2</accession>
    <name>A4S1W2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_33241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat DDB2/WDR76 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419218.1">
        <property type="nucleotide sequence ID" value="XM_001419181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1W2"/>
    <dbReference type="STRING" id="436017.A4S1W2"/>
    <dbReference type="GeneID" id="5003481"/>
    <dbReference type="Gramene" id="ABO97511">
        <property type="protein sequence ID" value="ABO97511"/>
        <property type="gene ID" value="OSTLU_33241"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33241"/>
    <dbReference type="eggNOG" id="KOG4328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_461825_0_0_1"/>
    <dbReference type="OMA" id="FSWFELQ"/>
    <dbReference type="OrthoDB" id="9890280at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000001">
        <property type="term" value="P:regulation of DNA damage checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050853">
        <property type="entry name" value="WD_repeat_DNA-damage-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="505" mass="54695" checksum="E9B6C0499AA72BC2" modified="2007-05-15" version="1">MKTEAVTRDDDDARANDDGSNDGLTAFERAREAHIARNKARMEALNINALSAGVGAASRGSAASSRGITGKRNRDKASAPSVPTRRSSRARKIAPELASGVDRERRDGTVVLANGATYHPSGELTAAPTRTRPSGEVAMRSENGSEKTDAAFIEELKTKMGAHVGETKEAKEATASVREMIKNKLTLRDVDVAKCVPKGVTHLDFSPDESMLLVASGDKEGHIGLWRVDKTTSEEEDEDDGVLYYKAHGSYISHCKWGRGALRGKLFTCAYDGAVRVLDPQTGSFQETVYSEEDEFSACDQFADGNTALVCDNVGNLHQLDLRVGKFTSPSLSIHEKKINTVHIDPGNEHRFATSTNQLVSVWDARKLKKNAKSTHDLVHRKSSQAAYWCPDGSGALLTTCYDDALRVWHPDRSAAAPTATIKHNNQTGRWVLPFRAVWSAAGDGVLCGSMTRQVEIFNPATGASLARYASPDHMTAIASRLACHRSLNYVAAGTASGRVHVYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Y9</accession>
    <name>A4S1Y9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419448.1">
        <property type="nucleotide sequence ID" value="XM_001419411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Y9"/>
    <dbReference type="STRING" id="436017.A4S1Y9"/>
    <dbReference type="GeneID" id="5003148"/>
    <dbReference type="Gramene" id="ABO97741">
        <property type="protein sequence ID" value="ABO97741"/>
        <property type="gene ID" value="OSTLU_24979"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24979"/>
    <dbReference type="eggNOG" id="KOG1922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_288615_0_0_1"/>
    <dbReference type="OMA" id="FFRLYYR"/>
    <dbReference type="OrthoDB" id="10475464at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1015"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1065" mass="116428" checksum="F9C7051A8324FC38" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S208</accession>
    <name>A4S208_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419243.1">
        <property type="nucleotide sequence ID" value="XM_001419206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S208"/>
    <dbReference type="GeneID" id="5003101"/>
    <dbReference type="Gramene" id="ABO97536">
        <property type="protein sequence ID" value="ABO97536"/>
        <property type="gene ID" value="OSTLU_16606"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16606"/>
    <dbReference type="HOGENOM" id="CLU_829880_0_0_1"/>
    <dbReference type="OMA" id="INAKYTM"/>
    <dbReference type="OrthoDB" id="495775at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="18"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="38024" checksum="ECBBB6629510E795" modified="2007-05-15" version="1">MHRASRASSIDDDTAQTLGLLQGQLRAQAREISRLQREVVDLHRERDVLAGKVLKPLNERFGDCVKDLIRETTWFKLKAVEETIDVNTYESTTRAAFDLAGARSMMEARFPDLKSAKITTREDIGAFGIEFKSRPFKGELMQFKARLNLEKLLNVAKAPTLALAPSPPFPWNGKTKWNPALESKMDIDGVSINAKYTMVHDSVSMDHLDFDVSTTHEEYGDLRVQRVSQHTAADDQLDIKPGGCWRAGWAQRKGDFDLAANFMTDKGVELELSARRQFAKHFSAKALTRVAAREMEFQVGYEFTEELKGWEVVAKSVLTTQGLQNPTFQLNHAWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2E6</accession>
    <name>A4S2E6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_35027</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419736.1">
        <property type="nucleotide sequence ID" value="XM_001419699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2E6"/>
    <dbReference type="STRING" id="436017.A4S2E6"/>
    <dbReference type="ESTHER" id="ostlu-a4s2e6">
        <property type="family name" value="abh_upf0017"/>
    </dbReference>
    <dbReference type="GeneID" id="5003671"/>
    <dbReference type="Gramene" id="ABO98029">
        <property type="protein sequence ID" value="ABO98029"/>
        <property type="gene ID" value="OSTLU_35027"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35027"/>
    <dbReference type="eggNOG" id="KOG1838">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032487_2_2_1"/>
    <dbReference type="OMA" id="LDWHGPH"/>
    <dbReference type="OrthoDB" id="247542at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034338">
        <property type="term" value="F:short-chain carboxylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF84">
        <property type="entry name" value="ESTERASE_LIPASE_THIOESTERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="115"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005211-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="402" mass="43972" checksum="0C5F1D09A2ACC419" modified="2007-05-15" version="1">MAVAATACAAWCALGSARETSEVRVTARRTKRNAYVLDKCGAILERGYDAVAWLKNRHASTILSSLLRRDLNVAYQREVLAMPDGGHATLDWPMSSALVRRRLAVHHARIAADAPVLVLMSGIAGGSHDKYLKHFLKRARARGFRCVAFNCRGTSESPLTTPQFYSASYTGDIRHVVNTLRERYPDAPLFAIGWSLGANILTNFLGEEGENAKVTGAAALCNPFDLNACDTALESGFFGKVYSQAMAKNMRKLFAPHENLFAGLPKYNPELVKAAKTVRDFDEAITRVTFGFPSVDAYYEYSGSKNKIGDVRVPLMTVQARDDPIAIADSIPRAIIEENPNVILLETESGGHLGWEAGPEAPFGAPWPDAVVMQFFEALLELKKSPNAKVETDTKVDPVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2H3</accession>
    <name>A4S2H3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_88195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419751.1">
        <property type="nucleotide sequence ID" value="XM_001419714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2H3"/>
    <dbReference type="STRING" id="436017.A4S2H3"/>
    <dbReference type="GeneID" id="5003648"/>
    <dbReference type="Gramene" id="ABO98044">
        <property type="protein sequence ID" value="ABO98044"/>
        <property type="gene ID" value="OSTLU_88195"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88195"/>
    <dbReference type="eggNOG" id="KOG1205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_1"/>
    <dbReference type="OMA" id="TWAWWLT"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45274">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45274:SF2">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="33924" checksum="2AB17E3281EEEB14" modified="2007-05-15" version="1" fragment="single">VWITGASQGLGEATARACARLGARVVVSGRRAERCAEVAEECARLGAASAKCVVFDVCGTRSELSEACERAFEAAGGTVDVFVNAAGGSQACSALAGDDEDVDKALFQLNAIGAISLTKEVAKRMVAAARRRKAGSIAPKIVGVCSVASKVPAPGQSVYAAAKSAYAAFLNSLRSEIANTGVKVVCVYPGPIATGMNGQERVIFRKNMADSTPSPSASKTAISRTAARPPSTKGRMNVDYVAARIVRSALADVDELVLAPQPIMALTYCVRFFPTLAYAALDVIGPKRARRADAGENMYDLLEKTREILESIGDVDSKDSKGKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2S2</accession>
    <name>A4S2S2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419796.1">
        <property type="nucleotide sequence ID" value="XM_001419759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2S2"/>
    <dbReference type="GeneID" id="5003791"/>
    <dbReference type="Gramene" id="ABO98089">
        <property type="protein sequence ID" value="ABO98089"/>
        <property type="gene ID" value="OSTLU_16814"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16814"/>
    <dbReference type="eggNOG" id="ENOG502T0UA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_761615_0_0_1"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF42">
        <property type="entry name" value="MAGNESIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="39639" checksum="9E271CD460730EB7" modified="2007-05-15" version="1">MVVRMGPTTTLVGPKCAYVFEPATRVAKNIVDTLRTWVGERDAAEGSAGAEARTVKDFPLAALECALEASSRYFEEKIFRLRRLARHCVDEISSDLRGDGKSGIVTGGSLNYNAAQWQKLPPIRRAIKEFEQDAREASEALNAAMTTTNLVPTPMDVVFDEKAAEERNDAVTDVLASHARRLAAVGGLVRELSADLDSARELWELQLDGDRNRTVQMNFRATVFALSAAVAAVPAGLGGMNMPHGLETAPIGVFWSVAGGILIGSTAVWYAFMRRFRKAGELTSARAGELASMQYILGNLDSLDNAFSGVDGSSVTREALRDVMRTEAGNVGAPSETEVFDLLFRIFDTDRSRAIDNAEWRRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S403</accession>
    <name>A4S403_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420010.1">
        <property type="nucleotide sequence ID" value="XM_001419973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S403"/>
    <dbReference type="GeneID" id="5003969"/>
    <dbReference type="Gramene" id="ABO98303">
        <property type="protein sequence ID" value="ABO98303"/>
        <property type="gene ID" value="OSTLU_17139"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17139"/>
    <dbReference type="eggNOG" id="ENOG502SI1T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_468881_0_0_1"/>
    <dbReference type="OrthoDB" id="10589850at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="405"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="502" mass="56623" checksum="820F97F6D0AA4454" modified="2007-05-15" version="1">MTSAAKALTRRSWKRAVRSMLDVYCESYAWDEESEQNDLSVVVKDVILKKSELEALLLTFGLHLGEGGCTFGKIRFCISLGLNMDMELFTKPWRIEVDHFRLNIGCGARAECDVRTEVNSQFDCSSEGSSRPTKMEEWLPLHRAVENLQLILRNATVTLHSINLAGSLIFKLDTVKYTTTNEHWSPMATITTSADYAGGILHKLLTFEGFEAYTDRAVSPSDSASVDCSGPWDLPFEDGTLLPVPQLTRVKVLFNGLQGNMKIIKKLKSSLTGRVVTDFFGDVYTFQLCLVSGGVPKVRIPHIALRLEWSEHIGTYVLNMEEAVQFSISHQIDAEILAETNAWLVQILEAHAEVAASTETQLSYERARRFQEQAYVGRLHKRLDEVKETFREKFLVWRSGTKSAIDELNMALSEEQQRREALEKAMKAQQEVLSQMYQQLQAQLVDASPVEQVNAVSQAMRAMSMSLDPKSNSTLPQRVPFEGGYQFGDVSRKALRWFSNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4J6</accession>
    <name>A4S4J6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420276.1">
        <property type="nucleotide sequence ID" value="XM_001420239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4J6"/>
    <dbReference type="GeneID" id="5004574"/>
    <dbReference type="Gramene" id="ABO98569">
        <property type="protein sequence ID" value="ABO98569"/>
        <property type="gene ID" value="OSTLU_25220"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25220"/>
    <dbReference type="eggNOG" id="ENOG502S8Q8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_499127_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="546" mass="59110" checksum="3A95BD6BF3807713" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4N8</accession>
    <name>A4S4N8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420467.1">
        <property type="nucleotide sequence ID" value="XM_001420430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4N8"/>
    <dbReference type="GeneID" id="5004545"/>
    <dbReference type="Gramene" id="ABO98760">
        <property type="protein sequence ID" value="ABO98760"/>
        <property type="gene ID" value="OSTLU_93445"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93445"/>
    <dbReference type="HOGENOM" id="CLU_1605447_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="166" mass="18649" checksum="A39DF505FCA4F80B" modified="2007-05-15" version="1">MAMDIMDTPEPMATPVPTSPVRARMDSETYTDCVPGILLLCVRSLHQARRSIASVVRSLAPAFAPAFAPIFISPSNPRRVRSTRARLVDRFARVLARAFDVDENVSPNPRARDRDEDSRRVAPRRVAHPPRDATDPSRESRGVARCRPSRARARIPHLNCDETMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Q5</accession>
    <name>A4S4Q5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Armadillo-type fold</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420476.1">
        <property type="nucleotide sequence ID" value="XM_001420439.1"/>
    </dbReference>
    <dbReference type="GeneID" id="5004553"/>
    <dbReference type="Gramene" id="ABO98769">
        <property type="protein sequence ID" value="ABO98769"/>
        <property type="gene ID" value="OSTLU_26492"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26492"/>
    <dbReference type="HOGENOM" id="CLU_243462_0_0_1"/>
    <dbReference type="OMA" id="HSNEMYR"/>
    <dbReference type="OrthoDB" id="10426957at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="479"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="676"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1351"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1484"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1368"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1495"/>
            <end position="1507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1507" mass="169247" checksum="2D99D706165789A9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4X0</accession>
    <name>A4S4X0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420342.1">
        <property type="nucleotide sequence ID" value="XM_001420305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4X0"/>
    <dbReference type="GeneID" id="5004521"/>
    <dbReference type="Gramene" id="ABO98635">
        <property type="protein sequence ID" value="ABO98635"/>
        <property type="gene ID" value="OSTLU_26558"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26558"/>
    <dbReference type="HOGENOM" id="CLU_2780394_0_0_1"/>
    <dbReference type="OMA" id="WTGRQQG"/>
    <dbReference type="OrthoDB" id="495262at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="69" mass="7786" checksum="53528ED1BAF0F933" modified="2007-05-15" version="1">MQEFEAAKSAILKVKPSANVIANRVDAYPITVRVSVGEREVWSGRQQLLFRKNGRPAMKDIEEAMRKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5K0</accession>
    <name>A4S5K0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FO synthase</fullName>
            <ecNumber evidence="7">2.5.1.147</ecNumber>
            <ecNumber evidence="6">4.3.1.32</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_51122</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-adenosyl-L-methionine = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 5'-deoxyadenosine + L-methionine + NH4(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:55204"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:59904"/>
            <dbReference type="ChEBI" id="CHEBI:85936"/>
            <dbReference type="EC" id="4.3.1.32"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine = 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + 5'-deoxyadenosine + L-methionine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:55200"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:85936"/>
            <dbReference type="EC" id="2.5.1.147"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme F0 biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the radical SAM superfamily. CofH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the radical SAM superfamily. CofG family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.147" evidence="7"/>
    <dbReference type="EC" id="4.3.1.32" evidence="6"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420784.1">
        <property type="nucleotide sequence ID" value="XM_001420747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5K0"/>
    <dbReference type="STRING" id="436017.A4S5K0"/>
    <dbReference type="GeneID" id="5004623"/>
    <dbReference type="Gramene" id="ABO99077">
        <property type="protein sequence ID" value="ABO99077"/>
        <property type="gene ID" value="OSTLU_51122"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51122"/>
    <dbReference type="eggNOG" id="ENOG502QUMN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010522_0_0_1"/>
    <dbReference type="OMA" id="HWVGHLN"/>
    <dbReference type="OrthoDB" id="2015542at2759"/>
    <dbReference type="UniPathway" id="UPA00072"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141093">
        <property type="term" value="F:5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044689">
        <property type="term" value="F:7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01611">
        <property type="entry name" value="FO_synth_sub1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01612">
        <property type="entry name" value="FO_synth_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019939">
        <property type="entry name" value="CofG_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045567">
        <property type="entry name" value="CofH/MnqC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019940">
        <property type="entry name" value="CofH_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020050">
        <property type="entry name" value="FO_synthase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00423">
        <property type="entry name" value="CofH family radical SAM protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03550">
        <property type="entry name" value="F420_cofG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03551">
        <property type="entry name" value="F420_cofH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004884">
        <property type="entry name" value="PRK06245.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="FO SYNTHASE (COFH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076:SF1">
        <property type="entry name" value="LIPOYL SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19288">
        <property type="entry name" value="CofH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="7_8-didemethyl-8-hydroxy-5-dea"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="7_8-didemethyl-8-hydroxy-5-dea"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00343">
        <property type="entry name" value="aminofutalosine_synthase_(mqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01064">
        <property type="entry name" value="F420__menaquinone_cofactor_bio"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01389">
        <property type="entry name" value="menaquinone_synthsis_involved"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="77"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="513"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO99077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="841" mass="91697" checksum="40DBCE70C805B9A6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5M8</accession>
    <name>A4S5M8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_39224</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420799.1">
        <property type="nucleotide sequence ID" value="XM_001420762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5M8"/>
    <dbReference type="STRING" id="436017.A4S5M8"/>
    <dbReference type="GeneID" id="5004755"/>
    <dbReference type="Gramene" id="ABO99092">
        <property type="protein sequence ID" value="ABO99092"/>
        <property type="gene ID" value="OSTLU_39224"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39224"/>
    <dbReference type="eggNOG" id="KOG1250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_6_0_1"/>
    <dbReference type="OMA" id="HFGVHGV"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04907">
        <property type="entry name" value="ACT_ThrD-I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000005">
        <property type="entry name" value="Threonine dehydratase catabolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006674">
        <property type="entry name" value="PRK09224.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="338"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="430"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="510" mass="55419" checksum="315AC260EAD60C14" modified="2007-05-15" version="1">MRPEAKDSDVAREAWYVRAILTADVYDVAIESPLELAPRLSDRVGAQIYLKREDLQPVFSFKIRGAYNKMKQLTEEERARGVITSSAGNHAQGVALSGQKLNCKAIIAMPVTTPAIKVEAVRRLGGTVELVGENYDATQAYAKERAAAEGLTYIPPFDDPYVIAGQGTVGVEVMRQLPSAEIIFVPIGGGGLAAGMVAYIKAIRPEIRVIGVEPAGANAMTLSLARGEIVKLSKVDGFADGVAVREPGRDCFEIIQTMIDGIITVKTDQIASAIKDVFGDTRSILEPAGAVAVAGAKAYCQAHGVTGKVIAVTSGANMNFDRLRVISEIADQGGKEEATLLSIIPEKNGEFKRFVETVGDINISEFKYRVQGADARVLYSIEVSDLKDVQNTMQRMEALGFKTVDLSNDATTQFHLRHMTGGQGRVENERLYKVEIPERAGALGNFLEFISPKWSISMTHYRNDGGRVGQVLFGVQVAEEEREVFEECLDGCGYKYDDMSSNIAFKTLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5T0</accession>
    <name>A4S5T0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420663.1">
        <property type="nucleotide sequence ID" value="XM_001420626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5T0"/>
    <dbReference type="GeneID" id="5004781"/>
    <dbReference type="Gramene" id="ABO98956">
        <property type="protein sequence ID" value="ABO98956"/>
        <property type="gene ID" value="OSTLU_26872"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26872"/>
    <dbReference type="HOGENOM" id="CLU_467275_0_0_1"/>
    <dbReference type="OMA" id="CAMERPR"/>
    <dbReference type="OrthoDB" id="2020984at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="584" mass="66811" checksum="3FC50F511B0520E0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5V7</accession>
    <name>A4S5V7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_17653</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420837.1">
        <property type="nucleotide sequence ID" value="XM_001420800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5V7"/>
    <dbReference type="STRING" id="436017.A4S5V7"/>
    <dbReference type="GeneID" id="5004697"/>
    <dbReference type="Gramene" id="ABO99130">
        <property type="protein sequence ID" value="ABO99130"/>
        <property type="gene ID" value="OSTLU_17653"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17653"/>
    <dbReference type="eggNOG" id="KOG1759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129906_1_1_1"/>
    <dbReference type="OMA" id="KSENWLM"/>
    <dbReference type="OrthoDB" id="255819at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004167">
        <property type="term" value="F:dopachrome isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050178">
        <property type="term" value="F:phenylpyruvate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="146" mass="15563" checksum="106F768D6A9EAF0C" modified="2007-05-15" version="1">MRVAIAPRARVATPRAALGAIRRDLVDLPGDPTLVVHTNVDMGSRKRAFMLAASRSVAKTLKKPESYVAVCVVDRADIVWGGSDDDCALCRLTSLGGIDLENNKAVSEDVCALLGETFGIAGTRVYVTFEDVARENMGYDSATFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="107" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6I7</accession>
    <name>A4S6I7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 4C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_13193</name>
        <name evidence="11" type="ORF">OSTLU_89884</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eIF-1A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421100.1">
        <property type="nucleotide sequence ID" value="XM_001421063.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422854.1">
        <property type="nucleotide sequence ID" value="XM_001422817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6I7"/>
    <dbReference type="STRING" id="436017.A4S6I7"/>
    <dbReference type="GeneID" id="5005157"/>
    <dbReference type="GeneID" id="5006912"/>
    <dbReference type="Gramene" id="ABO99393">
        <property type="protein sequence ID" value="ABO99393"/>
        <property type="gene ID" value="OSTLU_13193"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01213">
        <property type="protein sequence ID" value="ABP01213"/>
        <property type="gene ID" value="OSTLU_89884"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13193"/>
    <dbReference type="KEGG" id="olu:OSTLU_89884"/>
    <dbReference type="eggNOG" id="KOG3403">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109098_0_1_1"/>
    <dbReference type="OMA" id="KMEDQEY"/>
    <dbReference type="OrthoDB" id="274995at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018104">
        <property type="entry name" value="TIF_eIF-1A_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="EIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01262">
        <property type="entry name" value="IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="9">
        <location>
            <begin position="24"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP01213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="142" mass="16347" checksum="1481335F05A24E88" modified="2007-05-15" version="1">MPKSNSKGKGGKNRRRGKGGGEDEKRELIFKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVILKYLADEARSLKAYGELPDTFRVNDTDTFEEERDENDDFFDFDDINDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7B1</accession>
    <name>A4S7B1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_2153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421425.1">
        <property type="nucleotide sequence ID" value="XM_001421388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7B1"/>
    <dbReference type="GeneID" id="5005358"/>
    <dbReference type="Gramene" id="ABO99718">
        <property type="protein sequence ID" value="ABO99718"/>
        <property type="gene ID" value="OSTLU_2153"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2153"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_0_1_1"/>
    <dbReference type="OMA" id="GCESFHA"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010287">
        <property type="term" value="C:plastoglobule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF22">
        <property type="entry name" value="OS07G0227800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="1">
        <location>
            <begin position="44"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="397" mass="43907" checksum="53C5ED0F323E634B" modified="2007-05-15" version="1" fragment="single">APVIVRRTFEALGATYVKLGQFIASAPSVFPKEYVEEFQKCLDATEVTDFSIIKRTIEKDLGRSIDDVFATIDPVPLASASVAQVHRATLLGSGRDVVVKVLKPNVEDTLKADLSFVLIVSKVLQFLNPELSRTSLVDIVGDIRESMLEETDFRKEAQNVDAFRRYLEDAELTNIAKAPQVYKQFSGKRVMVMEYFSGVPLTDLEAIRSVSTRDPEATLINALNVWFGSVLACESFHADVHAGNLIVCPDGRVGFIDFGIVGKISPSIWGAVQAFFQSTAARDYERMALALVTMGATDGEVDVKKFANDLRKVYETLDSIEPTVLVDEDTFDGTPRAAVTVDQQQVTQLASDLIVAAEENKIKLPKAFGILIKQLIYFDRYVQLLAPDLEVIDDDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7H9</accession>
    <name>A4S7H9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_27494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421276.1">
        <property type="nucleotide sequence ID" value="XM_001421239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7H9"/>
    <dbReference type="STRING" id="436017.A4S7H9"/>
    <dbReference type="GeneID" id="5005326"/>
    <dbReference type="Gramene" id="ABO99569">
        <property type="protein sequence ID" value="ABO99569"/>
        <property type="gene ID" value="OSTLU_27494"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27494"/>
    <dbReference type="eggNOG" id="KOG0597">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003494_0_0_1"/>
    <dbReference type="OMA" id="MIGSHTC"/>
    <dbReference type="OrthoDB" id="24822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000914">
        <property type="term" value="P:phragmoplast assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14010">
        <property type="entry name" value="STKc_ULK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056980">
        <property type="entry name" value="ARM_RUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056981">
        <property type="entry name" value="HEAT_ULK4_RUNKEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044591">
        <property type="entry name" value="RUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46562">
        <property type="entry name" value="SERINE/THREONINE-KINASE ULK4-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46562:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ULK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24970">
        <property type="entry name" value="ARM_RUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23606">
        <property type="entry name" value="HEAT_ULK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="11"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="407"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1255" mass="139140" checksum="C46DB632B05CE9A1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7N4</accession>
    <name>A4S7N4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DMT family transporter: triose phosphate/phosphate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_18149</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421484.1">
        <property type="nucleotide sequence ID" value="XM_001421447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7N4"/>
    <dbReference type="STRING" id="436017.A4S7N4"/>
    <dbReference type="GeneID" id="5005461"/>
    <dbReference type="Gramene" id="ABO99777">
        <property type="protein sequence ID" value="ABO99777"/>
        <property type="gene ID" value="OSTLU_18149"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18149"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019048_0_3_1"/>
    <dbReference type="OMA" id="PCVRQNF"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="20"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="33690" checksum="3799D82FEA7F3D0A" modified="2007-05-15" version="1">MEANSGPLAEIKEKYPQLETVFYFAAWYFLNVQFNIINKTIYNYFPYPWFVSCVHLIVGLFIMAFFLGYQEFLKALSLPAFLHAFGHCLTNVSFAAVAVSFTHTVKTLEPVFTSIGSYLVAGTVYPLPVYLSLLPVIAGVAIASATELSFTWLGFLTAMSSNIAFSARAIFSKKLMSKMSPLNLYNWVTIVALLFCLPFAVYFEGPTLSAGISKAIAVKGKTEFLMALASVGFYYHMYNQVAYQALGKVAPVTHAVGNVGKRIFVIGFSILAFGNKISTQTLVGSAIAIVGAGLYGVMKGKYADESKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7N5</accession>
    <name>A4S7N5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_3566</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421304.1">
        <property type="nucleotide sequence ID" value="XM_001421267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7N5"/>
    <dbReference type="GeneID" id="5005277"/>
    <dbReference type="Gramene" id="ABO99597">
        <property type="protein sequence ID" value="ABO99597"/>
        <property type="gene ID" value="OSTLU_3566"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3566"/>
    <dbReference type="eggNOG" id="ENOG502QU5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042215_0_0_1"/>
    <dbReference type="OMA" id="WVHDPIA"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF2">
        <property type="entry name" value="LYSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="38387" checksum="FE671BDCCE7616A4" modified="2007-05-15" version="1" fragment="single">DDATATARKRRYVNVTGFPFPLTPVLRRKTTMETIVPGRVWALEQEQGIGFGLGVTTNVRMTVVRMRDGALWVHDPIAPTEECVELLAKIGGEVKYCCLSTTQYEHKIFAPAFTRAFPKCELWIAPGQFSFPLPLPNAFLGLFPKGTLGDSRNPPPWSDEIESELLYLPPLFWHNYTYCECAFYHKDTSSLLVTDAAVYVGENAPGIIPEDDLESLGSDDCFTIRLLKLGNYRGGRNIASPQIPASQREARVSNGWMRMALFSLFIAPDAKNILNPERSFRGMAGKFVVSPIVFNVVFQFYREEVAAWAEKVSRWNAERVIASHFPVPESASSADFLRAFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7P7</accession>
    <name>A4S7P7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421308.1">
        <property type="nucleotide sequence ID" value="XM_001421271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7P7"/>
    <dbReference type="STRING" id="436017.A4S7P7"/>
    <dbReference type="GeneID" id="5005465"/>
    <dbReference type="Gramene" id="ABO99601">
        <property type="protein sequence ID" value="ABO99601"/>
        <property type="gene ID" value="OSTLU_93721"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93721"/>
    <dbReference type="eggNOG" id="KOG2210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_579175_0_0_1"/>
    <dbReference type="OMA" id="HPPITTW"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="57781" checksum="7DF6C0C139C9A99A" modified="2007-05-15" version="1">MSCWCCFKGARKLDVASWRARFQPGEDDMWFDAREELHYGDEDDGLDDLTDENISIEANSEFPFTLGKVWEQEEHQSYVATAIREMKGKVRHVLRKQHEEAVRQAEEEAAELERLGLMTAEKRAMHERMTSGQGTQELVGMTKHLKVGQDLTDIELPPTFFVPFSTIQVAEDVVYVIEGCNNDWSDLKHPDPERRIARLVKLYLDMSAIRTEHGSSAGVKSAYTFGAMKKPLNPILGETHRIKSGNTEYLAEQVCHHPPITTWDLRNEEIGLHLSADVKAKPVFRGTSVQVLIDGEMRFENLHTGEKYVMDMPSLFIRFFGLSGSYSETVGHITLRRVSEGPPLCAELHFKPRGTTGLRSHANKVEGSISSETTTFMHFKGKFNDAVDEVTEKREFVRPFWRPAPPKSSKAPRAVTRPLNGFTDSHCLWGEFFQALIAKDMKTASKAKKKAERGQRSLHKAMKTGELPPWEPTMFATEDGERWLLKPNFNPSVQPSWLKYIGYRIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7T4</accession>
    <name>A4S7T4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421328.1">
        <property type="nucleotide sequence ID" value="XM_001421291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7T4"/>
    <dbReference type="GeneID" id="5005228"/>
    <dbReference type="Gramene" id="ABO99621">
        <property type="protein sequence ID" value="ABO99621"/>
        <property type="gene ID" value="OSTLU_93733"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93733"/>
    <dbReference type="HOGENOM" id="CLU_1996452_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="125" mass="14558" checksum="42CBEF98186331EF" modified="2007-05-15" version="1">MRVLDRRVRRRRTRRAVESRGRVAARCGAPTIDAFDPPRAIDRTRNSARSRERGRSAGDLSTIYLVCDRIRARKTRMCDRRFSAIGTDRTTRSERFYGPVVRRPLRKGKILGSIPSRSKSYIKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8I8</accession>
    <name>A4S8I8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_27866</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421774.1">
        <property type="nucleotide sequence ID" value="XM_001421737.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S8I8"/>
    <dbReference type="GeneID" id="5005711"/>
    <dbReference type="Gramene" id="ABP00068">
        <property type="protein sequence ID" value="ABP00068"/>
        <property type="gene ID" value="OSTLU_27866"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27866"/>
    <dbReference type="eggNOG" id="KOG1217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000388_0_0_1"/>
    <dbReference type="OMA" id="CETPCEP"/>
    <dbReference type="OrthoDB" id="18487at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN,N-TERMINAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967:SF1">
        <property type="entry name" value="KERATIN-ASSOCIATED PROTEIN 16-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17963">
        <property type="entry name" value="Big_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671926" description="EGF-like domain-containing protein" evidence="4">
        <location>
            <begin position="35"/>
            <end position="3182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1384"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1410"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1477"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1519"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1581"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1661"/>
            <end position="1680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1692"/>
            <end position="1717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1729"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="207"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3078"/>
            <end position="3122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3145"/>
            <end position="3182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="3082"/>
            <end position="3093"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="3182" mass="352853" checksum="0D066A4C475D5EF9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8P8</accession>
    <name>A4S8P8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_7611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EMC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421799.1">
        <property type="nucleotide sequence ID" value="XM_001421762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8P8"/>
    <dbReference type="STRING" id="436017.A4S8P8"/>
    <dbReference type="GeneID" id="5005775"/>
    <dbReference type="Gramene" id="ABP00093">
        <property type="protein sequence ID" value="ABP00093"/>
        <property type="gene ID" value="OSTLU_7611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7611"/>
    <dbReference type="eggNOG" id="KOG3060">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052388_1_1_1"/>
    <dbReference type="OMA" id="LFCYEEV"/>
    <dbReference type="OrthoDB" id="124397at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055217">
        <property type="entry name" value="TPR_EMC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22890">
        <property type="entry name" value="TPR_EMC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EMC2 TPR-like" evidence="5">
        <location>
            <begin position="9"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="187" mass="20894" checksum="1335B34B35E84E2A" modified="2007-05-15" version="1" fragment="single">ATTLGKEGGAAEARKMLDEMLEENKGEARLRKMRVACAKSEGDVPGAVAALTEYLEDFGADDEAWLELGKLYAERCEYEKALFCYEEVLCARPFDPNSHRRMGEVLYTMGGEENIRDAKHHFAAAIDFTNGKDIRALYAVILCVKKLRIMSSKRGEEFKDNGALELADAATERLLQRYASDNETLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8S8</accession>
    <name>A4S8S8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_27955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Prolyl cis/trans isomerase with specificity for phospho-Ser-Pro bonds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PpiC/parvulin rotamase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421810.1">
        <property type="nucleotide sequence ID" value="XM_001421773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8S8"/>
    <dbReference type="STRING" id="436017.A4S8S8"/>
    <dbReference type="GeneID" id="5005972"/>
    <dbReference type="Gramene" id="ABP00104">
        <property type="protein sequence ID" value="ABP00104"/>
        <property type="gene ID" value="OSTLU_27955"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27955"/>
    <dbReference type="eggNOG" id="KOG3259">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090028_4_0_1"/>
    <dbReference type="OMA" id="RMSRSSX"/>
    <dbReference type="OrthoDB" id="2530521at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009630">
        <property type="term" value="P:gravitropism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032880">
        <property type="term" value="P:regulation of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000010">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase Pin1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051370">
        <property type="entry name" value="PPIase_Pin1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10657">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10657:SF4">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="8">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="10092" checksum="DA2A2B94707AAB08" modified="2007-05-15" version="1">MTDESATTTTTQTKEAAIDELLRYRDAVANGEATFADVAKKVSDCSSAKRGGDLGEFGPGQMQRAFEDATYALKIGEMSEAVETDSGVHVILRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Y5</accession>
    <name>A4S8Y5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421839.1">
        <property type="nucleotide sequence ID" value="XM_001421802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Y5"/>
    <dbReference type="STRING" id="436017.A4S8Y5"/>
    <dbReference type="GeneID" id="5005868"/>
    <dbReference type="Gramene" id="ABP00133">
        <property type="protein sequence ID" value="ABP00133"/>
        <property type="gene ID" value="OSTLU_28010"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28010"/>
    <dbReference type="eggNOG" id="KOG1491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018395_1_0_1"/>
    <dbReference type="OMA" id="DFHDLCE"/>
    <dbReference type="OrthoDB" id="424823at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900425">
        <property type="term" value="P:negative regulation of defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901001">
        <property type="term" value="P:negative regulation of response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="24"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="308"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="33"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="400" mass="44650" checksum="8985BB3E36DF640F" modified="2007-05-15" version="1">MPPKKVVQEEVLGPWSLGRFSSNLKVGIVGMPNVGKSTLYNALTNCAIPAENFPFCTIEPNSTRVNVPDARFDWLVEQNKPKSVVAPYLEIVDIAGLVKGASTGAGLGNSFLSHIKAVDGIAHVMRCFEDADVIHVEDRVDPVDDIEIITSELRAKDLEFMSALKEKTEKEVTRAANAMAAKEQKQELETICKVVDWLESGKEVRHGMEQWTSNDVMYLNKYQLLTAKPVIYLVNLSRKDFERKKNKFLVKIHEWVQAHGGGTIIPFSAEVESELQHVAEEDKAQWCKDRGVQTMLPKIITTAFSTVHLIYFFTAGPDEVKAWCIRKGYKAPQAAGAIHTDFERGFICAEVMAFDDLKELGSEQAVKTAGKYRQEGKTYTVQDADVIFFKFNVSGAAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9C2</accession>
    <name>A4S9C2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Shieldin complex subunit 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421909.1">
        <property type="nucleotide sequence ID" value="XM_001421872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9C2"/>
    <dbReference type="GeneID" id="5005938"/>
    <dbReference type="Gramene" id="ABP00203">
        <property type="protein sequence ID" value="ABP00203"/>
        <property type="gene ID" value="OSTLU_93885"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93885"/>
    <dbReference type="HOGENOM" id="CLU_052192_0_0_1"/>
    <dbReference type="OrthoDB" id="10519565at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010569">
        <property type="term" value="P:regulation of double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029715">
        <property type="entry name" value="FAM35A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031589">
        <property type="entry name" value="SHLD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14495">
        <property type="entry name" value="SHIELDIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14495:SF2">
        <property type="entry name" value="SHIELDIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15793">
        <property type="entry name" value="SHLD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shieldin complex subunit 2 C-terminal" evidence="1">
        <location>
            <begin position="201"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="353" mass="39039" checksum="DA4FA9C9F6C34E91" modified="2007-05-15" version="1" fragment="single">VDAAEARRRESFGREAGYVEVEALDGTSAALVHVLGRVVRETIAPSSWRPRAGGRDGARYVRRIVWVVQTHGGRCVAICLPPTTEAAAAERSLLKDGAVIDVRNALVRRNAQTGVCDLVCDVRSHWRALDGKDPRYADVCARAPKSAFEQTLTFEALALAMHSNGFARASSMIRFKACVRWVKVATERRRVPPMLRETDSSVTAAMTYLACLACSRELETDHNNVYKMCHCTSNDARCGFVWRDIVLGMQSDHGDSKTVIPVRARGDIARRLLFNVDASSVLDEHASDDEFDDFDDDDAAPRSDHKKVVVAAINALAAGRRNAAMDWRVKFPALDENGLPRRDELELVDFNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9G6</accession>
    <name>A4S9G6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione-specific gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422061.1">
        <property type="nucleotide sequence ID" value="XM_001422024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9G6"/>
    <dbReference type="STRING" id="436017.A4S9G6"/>
    <dbReference type="GeneID" id="5005960"/>
    <dbReference type="Gramene" id="ABP00355">
        <property type="protein sequence ID" value="ABP00355"/>
        <property type="gene ID" value="OSTLU_13383"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13383"/>
    <dbReference type="eggNOG" id="KOG3182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070703_2_2_1"/>
    <dbReference type="OMA" id="DHREKDG"/>
    <dbReference type="OrthoDB" id="1933483at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061928">
        <property type="term" value="F:glutathione specific gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006840">
        <property type="entry name" value="ChaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192">
        <property type="entry name" value="CATION TRANSPORT PROTEIN CHAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192:SF2">
        <property type="entry name" value="GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04752">
        <property type="entry name" value="ChaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="193" mass="21505" checksum="8FC5EBD52F53414A" modified="2007-05-15" version="1">MPRAPLSTRANESLWVFGYGSIVWRTGFEYARSIAPVCARGFRRRFYQGSTDHRGTPAAPGRTATLERCSEDVACWGVAYEVRAEDREAVLENLEIREKQYDERIEMDLYDVDDANAVPVIRNAVTYIATPATTNLNWLGDASDVAEQIAAARGPSGENSEYLYNLCEALRGLGIEDEELYALEASVRAIRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9L7</accession>
    <name>A4S9L7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_28244</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422089.1">
        <property type="nucleotide sequence ID" value="XM_001422052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9L7"/>
    <dbReference type="STRING" id="436017.A4S9L7"/>
    <dbReference type="MEROPS" id="S10.009"/>
    <dbReference type="GeneID" id="5006250"/>
    <dbReference type="Gramene" id="ABP00406">
        <property type="protein sequence ID" value="ABP00406"/>
        <property type="gene ID" value="OSTLU_28244"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28244"/>
    <dbReference type="eggNOG" id="KOG1282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008523_10_1_1"/>
    <dbReference type="OMA" id="GDWMKPF"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006521797" description="Carboxypeptidase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="526" mass="57533" checksum="BD822993FC5793DE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9P7</accession>
    <name>A4S9P7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DASS family transporter: 2-oxoglutarate/malate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_28272</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422207.1">
        <property type="nucleotide sequence ID" value="XM_001422170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9P7"/>
    <dbReference type="GeneID" id="5006163"/>
    <dbReference type="Gramene" id="ABP00524">
        <property type="protein sequence ID" value="ABP00524"/>
        <property type="gene ID" value="OSTLU_28272"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28272"/>
    <dbReference type="eggNOG" id="ENOG502QQ8W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005170_7_3_1"/>
    <dbReference type="OMA" id="PQAWRYF"/>
    <dbReference type="OrthoDB" id="1695362at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015140">
        <property type="term" value="F:malate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030676">
        <property type="entry name" value="CitT-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42826">
        <property type="entry name" value="DICARBOXYLATE TRANSPORTER 2.1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002457">
        <property type="entry name" value="DASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="498"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="527" mass="55115" checksum="0A65D1823C1EC5BB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Q5</accession>
    <name>A4S9Q5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_42158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422213.1">
        <property type="nucleotide sequence ID" value="XM_001422176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9Q5"/>
    <dbReference type="STRING" id="436017.A4S9Q5"/>
    <dbReference type="GeneID" id="5006270"/>
    <dbReference type="Gramene" id="ABP00530">
        <property type="protein sequence ID" value="ABP00530"/>
        <property type="gene ID" value="OSTLU_42158"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42158"/>
    <dbReference type="eggNOG" id="ENOG502QPN7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019746_0_0_1"/>
    <dbReference type="OMA" id="VVPWMMF"/>
    <dbReference type="OrthoDB" id="2019015at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF20">
        <property type="entry name" value="FLAVIN-CONTAINING AMINE OXIDASEDEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="461" mass="52142" checksum="758FE79868959011" modified="2007-05-15" version="1">MRVVVVGGGAAGCAASFALARAGADVETLERGDALGGVATSEVVGGTTINDGVQGGATSYANARAIMEACGTETPHWVDVRVSFGRGEAHWRNHGEATALTRALRDDIARFEKTLKRIKRFEALYAFVSVERALRWHGHSKAFRDRMVYATTALFFGTGNCTRKVSSIVLARVFNDDRLRLYDYDPVRFMSEAPKMFAFPKFSEMYRRIGEDITSHGGRVTLNARVVKVEREKKCVRVHFENAEGAIEVRECDRVIFACNTEQSKAMLDAGTGTSMMERHIFNNIEYFDDVSVTHSDEAYMKKHYEVAEDVRDMYFIKSYDDDPSLCEMSFDLTAYQPFAKGANGERVYQSIFLNAAKDKSRWTRDEIDPNRVLLVKWWRQFGHTVRHFTRAVPFWRFVQNKRRTLYAGSYTSVNTHEIAIISGLVAAYRCGAPYPFADDVAASFQFDLYASIIHGVKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9R1</accession>
    <name>A4S9R1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_41984</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422216.1">
        <property type="nucleotide sequence ID" value="XM_001422179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9R1"/>
    <dbReference type="STRING" id="436017.A4S9R1"/>
    <dbReference type="GeneID" id="5006273"/>
    <dbReference type="Gramene" id="ABP00533">
        <property type="protein sequence ID" value="ABP00533"/>
        <property type="gene ID" value="OSTLU_41984"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41984"/>
    <dbReference type="eggNOG" id="KOG1164">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019279_2_5_1"/>
    <dbReference type="OMA" id="MTEYKGP"/>
    <dbReference type="OrthoDB" id="497611at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="29"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP00533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="35310" checksum="9A33DF5EDE6A02D8" modified="2007-05-15" version="1" fragment="single">MSKSTTQFAQPHNLLKPGARLGADGRFTVASAPKLGRGQFAEVYAANDATRDGARVAVKVESEHRTSAREARVMRAMAGKEHFAELLLESSHEGKPFLAMELVGENLADLRSRARGGRFGPRTTCAIAIAMLDALESMHGAGYVHRDIKPGNVCVGNGKEGMKRLYLIDFGLARKFTDDDGNVLPERDDATFRGTTTYASVYAHENKEQSARDDLFSALYVLVEAHEGVLPWKAGEEKMSKQNVEREKKKCVKNPALLCPKHGCPTAIETFARAIATLEYGQTPDYAALRAPFEDVVRNAGDTPLDWEAGAAPPPSLQTTKGAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAE3</accession>
    <name>A4SAE3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_28539</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422421.1">
        <property type="nucleotide sequence ID" value="XM_001422384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAE3"/>
    <dbReference type="GeneID" id="5006478"/>
    <dbReference type="Gramene" id="ABP00738">
        <property type="protein sequence ID" value="ABP00738"/>
        <property type="gene ID" value="OSTLU_28539"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28539"/>
    <dbReference type="eggNOG" id="ENOG502STQU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_11_0_1"/>
    <dbReference type="OMA" id="DAKAFPW"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051257">
        <property type="entry name" value="Diverse_CBS-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080:SF29">
        <property type="entry name" value="OS02G0818000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="74"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="158" mass="17362" checksum="E118D25E4DD410F8" modified="2007-05-15" version="1">MVPTCRDFMTPARACITATTDDTIESVVHALAYDGVGCVCVLDAGKPVGVVTKADALEWWLEKLPMDCACGAVANKAVIQASPWMTRDEVSAVLMRNRVHHVAVTDRDGVFVGLVSAWDIAREVGRAYELPFWQEFFERVRQPRLRGSRPTRSSAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAK6</accession>
    <name>A4SAK6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_42284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422448.1">
        <property type="nucleotide sequence ID" value="XM_001422411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAK6"/>
    <dbReference type="GeneID" id="5006465"/>
    <dbReference type="Gramene" id="ABP00765">
        <property type="protein sequence ID" value="ABP00765"/>
        <property type="gene ID" value="OSTLU_42284"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42284"/>
    <dbReference type="eggNOG" id="KOG1470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014001_9_3_1"/>
    <dbReference type="OMA" id="YFPKRIS"/>
    <dbReference type="OrthoDB" id="496270at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070300">
        <property type="term" value="F:phosphatidic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901981">
        <property type="term" value="F:phosphatidylinositol phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47556">
        <property type="entry name" value="SEC14P-LIKE PHOSPHATIDYLINOSITOL TRANSFER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47556:SF1">
        <property type="entry name" value="SEC14P-LIKE PHOSPHATIDYLINOSITOL TRANSFER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="66"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="24721" checksum="DA6DADF22EBE866F" modified="2007-05-15" version="1">MRASRDDASDDASDDAELLASAPDWLLAWFLRDRKLDADKARAKTLKYLEWRRSGYGESELKLSSEVAEEAASGKAVLLGERDAQNRPVVYVTLTKHDVETRELSRTCRLCVKLVDEALEQLRGEGAGAPETLMCVFDLRGFTMKNADIDFVKFFIKCIFDYFPKRISQVLLIEPPWVFTPVWQIVKPLMGKYAALVKQVKAKDAKAYFDPESTLFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAL2</accession>
    <name>A4SAL2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_18911</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422451.1">
        <property type="nucleotide sequence ID" value="XM_001422414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAL2"/>
    <dbReference type="STRING" id="436017.A4SAL2"/>
    <dbReference type="GeneID" id="5006509"/>
    <dbReference type="Gramene" id="ABP00768">
        <property type="protein sequence ID" value="ABP00768"/>
        <property type="gene ID" value="OSTLU_18911"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18911"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1369361_0_0_1"/>
    <dbReference type="OMA" id="MNERATE"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="200" mass="22690" checksum="97B9097E0DFC87A8" modified="2007-05-15" version="1" fragment="single">MVVKAPKDYAREPPRGWSSKWSWTTLDGDDRAQTGADARKLFEEPQFHKRARIGDLLGVRAMLDARTVDVDDVDAGGRTALHFAVGFGREHVARELLDRGAALETRDDWGKAPVDFAMQGLHDECIQMLRMEAVKRGVWGGRGRVAPLKTYYEYAYNLTNEEVHVQIEKHAREASENYTRQAKADSASYNEQRAELQRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAT3</accession>
    <name>A4SAT3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29372</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of a prohibitin multimeric complex in mitochondrial membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the prohibitin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422659.1">
        <property type="nucleotide sequence ID" value="XM_001422622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAT3"/>
    <dbReference type="STRING" id="436017.A4SAT3"/>
    <dbReference type="GeneID" id="5006552"/>
    <dbReference type="Gramene" id="ABP00976">
        <property type="protein sequence ID" value="ABP00976"/>
        <property type="gene ID" value="OSTLU_29372"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29372"/>
    <dbReference type="eggNOG" id="KOG3090">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047969_0_2_1"/>
    <dbReference type="OMA" id="NEGTHFQ"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="8">
        <location>
            <begin position="27"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="30741" checksum="8AE790299C41AEBF" modified="2007-05-15" version="1">MPNASVVSAALQTLVYGGAASYGLYNSLFNVEGGHRAIVYNRFVGVKDKVYAEGTHFMIPWVERPYVYDVRARAHQVNSQSGSRDLQMVNISIRVLTRPDAGKLPEVYRTLGMDFNERVLPSVIHETVKSVVAQHNASELITKREQVSLSIRHLLKQRAAQFNMVLDDVSLTALTFGREYTAAIESKQVAQQEAERAKFVVDKARQDKLSAVIQAEGEAKSAKLIGEAIANNPAFLTLRKIEAARAIAQTMANSNNRVMLSADSLLLNLQDDKPADKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB98</accession>
    <name>A4SB98_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mur ligase central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_43806</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422580.1">
        <property type="nucleotide sequence ID" value="XM_001422543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB98"/>
    <dbReference type="STRING" id="436017.A4SB98"/>
    <dbReference type="GeneID" id="5006795"/>
    <dbReference type="Gramene" id="ABP00897">
        <property type="protein sequence ID" value="ABP00897"/>
        <property type="gene ID" value="OSTLU_43806"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43806"/>
    <dbReference type="eggNOG" id="ENOG502QTHZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022291_4_0_1"/>
    <dbReference type="OMA" id="FLHYDTR"/>
    <dbReference type="OrthoDB" id="533138at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010020">
        <property type="term" value="P:chloroplast fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.10">
        <property type="entry name" value="MurE/MurF, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23135">
        <property type="entry name" value="MUR LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23135:SF4">
        <property type="entry name" value="UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE MURE HOMOLOG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="3">
        <location>
            <begin position="212"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Mur ligase C-terminal" evidence="2">
        <location>
            <begin position="456"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="680" mass="73074" checksum="A4BBAA8FA9421E61" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBE9</accession>
    <name>A4SBE9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422605.1">
        <property type="nucleotide sequence ID" value="XM_001422568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBE9"/>
    <dbReference type="GeneID" id="5006663"/>
    <dbReference type="Gramene" id="ABP00922">
        <property type="protein sequence ID" value="ABP00922"/>
        <property type="gene ID" value="OSTLU_29584"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29584"/>
    <dbReference type="HOGENOM" id="CLU_587124_0_0_1"/>
    <dbReference type="OMA" id="PDWSAYF"/>
    <dbReference type="OrthoDB" id="10427649at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671974" evidence="2">
        <location>
            <begin position="22"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="466" mass="50921" checksum="3B96D50613C0683A" modified="2007-05-15" version="1">MRGRSVRRALALALACGLAMARDAEGARRASVNASGVFNTNGLRCPEDVECERCAAPLNAAPFRAPVNLTGVRVIGCRYRADVCDALREESKACKRHARSLCGEQDTRAQAKTKCKREMNRAWKTRCKEERTMMVSRADGALKRFLEVLEKLKRARAKRAAGGAGDDLTMLEMELSRLKTSIGHAFEELRSNHGGVAVGLMSDRMEAFVRGPTLLDSTSDMLDVVNAMNAVLGELQGLSTEAKSLCSYDANMDTSDGKILCQDMEEKMKLSEKRVNRCAARLSDYLASTAKIDALIVEKKRRFALLDSLDKFTDSISGAWSAVQYEGDDDFVEEPSTRFNLTEHVTTGIVHTLMNHYTTVSARHALATAEIKESALCAHIIPRFQLSLLGTGFKRGDLACPPPHGTFIAGRELPDWSAYFLFLLGIAVGAGATIATNRANEAVDFVRTNSSVVVAVLVVVLAGRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBF8</accession>
    <name>A4SBF8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RND family transporter: Patched (Ptc) segmentation polarity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_29594</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422769.1">
        <property type="nucleotide sequence ID" value="XM_001422732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBF8"/>
    <dbReference type="STRING" id="436017.A4SBF8"/>
    <dbReference type="GeneID" id="5006826"/>
    <dbReference type="Gramene" id="ABP01086">
        <property type="protein sequence ID" value="ABP01086"/>
        <property type="gene ID" value="OSTLU_29594"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29594"/>
    <dbReference type="eggNOG" id="KOG1935">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_276862_0_0_1"/>
    <dbReference type="OMA" id="KLNGASM"/>
    <dbReference type="OrthoDB" id="567451at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46022">
        <property type="entry name" value="PROTEIN PATCHED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46022:SF1">
        <property type="entry name" value="PROTEIN PATCHED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="585"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="649"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="674"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="755"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1036"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1091"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1119"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1154"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="526"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP01086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1183" mass="129354" checksum="5C4BF415AF67D452" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBH8</accession>
    <name>A4SBH8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_7767</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probable phosphatase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CTDSPL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422622.1">
        <property type="nucleotide sequence ID" value="XM_001422585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBH8"/>
    <dbReference type="STRING" id="436017.A4SBH8"/>
    <dbReference type="GeneID" id="5006680"/>
    <dbReference type="Gramene" id="ABP00939">
        <property type="protein sequence ID" value="ABP00939"/>
        <property type="gene ID" value="OSTLU_7767"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7767"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020262_4_5_1"/>
    <dbReference type="OMA" id="WHMENAI"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000015">
        <property type="entry name" value="CTD small phosphatase-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="5">
        <location>
            <begin position="10"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="190" mass="21989" checksum="0BE0FD222D97C322" modified="2007-05-15" version="1" fragment="single">KGPVLPARDEHDTRNTLVLDLDETLVHSNLENTVERCDFSFPVVFNGDMHRVNVRKRPHLSTFMELVSKQYEIVVFTASQQIYADKLLDILDPSQKWIKHRIFRDSCVQIDGNFMKDLRVLGRDLSRTIIIDNSPQAFGLQVENGIPIESWYDDDADNHLLSLLPILNELAADTDVRVTLDRMFNLRERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBT7</accession>
    <name>A4SBT7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422834.1">
        <property type="nucleotide sequence ID" value="XM_001422797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBT7"/>
    <dbReference type="GeneID" id="5006974"/>
    <dbReference type="Gramene" id="ABP01193">
        <property type="protein sequence ID" value="ABP01193"/>
        <property type="gene ID" value="OSTLU_25942"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25942"/>
    <dbReference type="HOGENOM" id="CLU_461819_0_0_1"/>
    <dbReference type="OMA" id="RTTAYWT"/>
    <dbReference type="OrthoDB" id="496223at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP01193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="59069" checksum="3C4850785C015411" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQD8</accession>
    <name>A4RQD8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415371.1">
        <property type="nucleotide sequence ID" value="XM_001415334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQD8"/>
    <dbReference type="GeneID" id="4999761"/>
    <dbReference type="Gramene" id="ABO93663">
        <property type="protein sequence ID" value="ABO93663"/>
        <property type="gene ID" value="OSTLU_28629"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28629"/>
    <dbReference type="HOGENOM" id="CLU_2577015_0_0_1"/>
    <dbReference type="OMA" id="VAPGWQN"/>
    <dbReference type="OrthoDB" id="10499677at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="84" mass="9382" checksum="2EBC8D00034616AF" modified="2007-05-15" version="1">MVAPGWQNKKKKTLKARDSKNSKALKLKRGTKAKHDAMKKRVSGKARTGKAARHALRNERRAARNAIDDAAKKASMENQDVVMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQP7</accession>
    <name>A4RQP7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415423.1">
        <property type="nucleotide sequence ID" value="XM_001415386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQP7"/>
    <dbReference type="GeneID" id="4999889"/>
    <dbReference type="Gramene" id="ABO93715">
        <property type="protein sequence ID" value="ABO93715"/>
        <property type="gene ID" value="OSTLU_28737"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28737"/>
    <dbReference type="HOGENOM" id="CLU_3109781_0_0_1"/>
    <dbReference type="OrthoDB" id="10469883at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="51" mass="5548" checksum="39EBE4D671E86D10" modified="2007-05-15" version="1">MTGGVLGMGAKKTGERACERCNEGTKKTPGRIACGRCQGNKFLLFRSADWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQU7</accession>
    <name>A4RQU7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_92098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415450.1">
        <property type="nucleotide sequence ID" value="XM_001415413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQU7"/>
    <dbReference type="STRING" id="436017.A4RQU7"/>
    <dbReference type="GeneID" id="4999568"/>
    <dbReference type="KEGG" id="olu:OSTLU_92098"/>
    <dbReference type="HOGENOM" id="CLU_084887_0_0_1"/>
    <dbReference type="OMA" id="NSEAWCA"/>
    <dbReference type="OrthoDB" id="250836at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051767">
        <property type="entry name" value="Nucleoporin_NUP42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527:SF1">
        <property type="entry name" value="NUCLEOPORIN NUP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527">
        <property type="entry name" value="NUCLEOPORIN-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="151"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="221" mass="21882" checksum="7B6C4DC8F9B67C35" modified="2007-05-15" version="1" fragment="single">LLDEKPNWALSCYGPKGEQPNLLGGDTSFEELRCAAYATVRAGGDAGGAHARAREYADAKAGDVKGILAFPEHQLKLVLDRVERGEMAPAGADRVMDGTAIVGGGGGFSRTHAPALDARATPFAPAGGMASGFTGNQPSLTPVATGFVASAQPTSPFGGGPGGGASPFGGGPGGASPFGGGNAPRAPSLTPDPNVPNSEAWCAPSFDIGGVPDDPPPAAYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRC4</accession>
    <name>A4RRC4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Coenzyme Q-binding protein COQ10 START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415547.1">
        <property type="nucleotide sequence ID" value="XM_001415510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRC4"/>
    <dbReference type="STRING" id="436017.A4RRC4"/>
    <dbReference type="GeneID" id="4999965"/>
    <dbReference type="Gramene" id="ABO93839">
        <property type="protein sequence ID" value="ABO93839"/>
        <property type="gene ID" value="OSTLU_28967"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28967"/>
    <dbReference type="eggNOG" id="ENOG502QSKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_446461_0_0_1"/>
    <dbReference type="OMA" id="QARDFME"/>
    <dbReference type="OrthoDB" id="2779at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34060:SF2">
        <property type="entry name" value="OS03G0837900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34060">
        <property type="entry name" value="POLYKETIDE CYCLASE / DEHYDRASE AND LIPID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="2">
        <location>
            <begin position="338"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="668"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="688" mass="76111" checksum="2B30F0C5073598C9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRF5</accession>
    <name>A4RRF5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ShKT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_28999</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415891.1">
        <property type="nucleotide sequence ID" value="XM_001415854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRF5"/>
    <dbReference type="STRING" id="436017.A4RRF5"/>
    <dbReference type="GeneID" id="5000008"/>
    <dbReference type="Gramene" id="ABO94183">
        <property type="protein sequence ID" value="ABO94183"/>
        <property type="gene ID" value="OSTLU_28999"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28999"/>
    <dbReference type="eggNOG" id="ENOG502QQG8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_477654_0_0_1"/>
    <dbReference type="OMA" id="PPWISEM"/>
    <dbReference type="OrthoDB" id="2015991at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF7">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="9">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="508" mass="58395" checksum="854E5416CA12FFE6" modified="2007-05-15" version="1">MHTVFSTECNGYFDWQSYGLYDSWRRVGQRGKFTRLMACDDENSPSLRVVPDTHVHPNYATHPVTKDSYTAYNKPFSIHHWLTNAEVTADFIIVLDADMIFRAPMTVDLLGVRRGAPVSAKYGYLIGTQPESHMGVKARVRNVEKAQQVGGFTVMHREDMRKLAPRWLYWTEEVRQDPDSWANTGDIYNANGKYGPPWISEMYGYVFAAAEVGITFQVHDDFMLYPGYDPPSDSRFPVVLHYGLTFNVQDYAFDKQWFHRSVLGCPTPELFQRPPTLAELRSKGPQRRRDEVALVCAWGLYNATRQYAIERCGIANPIDTRKIHYSCSKDARGVLSCSERKNTDDTFRGGGGDDDEEECRDTNDMCCGWAHDGECEKNPSFMLQSCPRSCDTCTVRCESRCCPPEKEAVKEETETQNDLNKPMNDGASTVRDDKVEDELHSFEDAREDEPLRAVEKDFATTPDDESGWYTYWHAFLISSTLLFCVVRIRLALKRRARRRSRHYVVVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRU1</accession>
    <name>A4RRU1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial ribonuclease P catalytic subunit</fullName>
            <ecNumber evidence="5">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Mitochondrial ribonuclease P protein 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_29136</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="5"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415960.1">
        <property type="nucleotide sequence ID" value="XM_001415923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRU1"/>
    <dbReference type="STRING" id="436017.A4RRU1"/>
    <dbReference type="GeneID" id="4999684"/>
    <dbReference type="Gramene" id="ABO94252">
        <property type="protein sequence ID" value="ABO94252"/>
        <property type="gene ID" value="OSTLU_29136"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29136"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014066_2_0_1"/>
    <dbReference type="OMA" id="ACQRETR"/>
    <dbReference type="OrthoDB" id="46913at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18718">
        <property type="entry name" value="PIN_PRORP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033495">
        <property type="entry name" value="MRPP3_PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031595">
        <property type="entry name" value="PRORP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13547">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13547:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16953">
        <property type="entry name" value="PRORP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="18">
        <location>
            <begin position="2"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="PRORP" evidence="17">
        <location>
            <begin position="151"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO94252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="374" mass="42055" checksum="199D8EF9E40C9828" modified="2007-05-15" version="1">MSEMSYTALARVRAAAGDVEGALDAARALKEEKLTPKVRTYACALHASAKKGDLEKMEAVEAMLRDEGLLPTELEFMAMLRAYRAAEAFDGGFAMLRRMRTEIRSPSDEMSEELRAWFSAVPGWSVADEVRVDDAGAAVAVLAMEEKRVELQLKAISLTEEERADLLAGIAKLACEREAQSEFDNFMNWLNVKKDGMNAIVDGANVGMYNQNFSTSGMNFNQVEKVLVELRKRAKEGDAPPIAFLHQRRVEGGPARKPHNQALLAKWDGAGELFTTAHGSNDDWYWLYAAVHAGDKAFLVTNDECRDHVFQMLPSPKLFYRWKERHQVRFTITAGEVELDYPAVFTTCMQEADDSSWWMFPQEDESWLCACKVE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-03-23" modified="2025-02-05" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS24</accession>
    <name>DRE2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anamorsin homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Fe-S cluster assembly protein DRE2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ORF">OSTLU_29219</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anamorsin family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="ABO93958" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93958.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415666.1">
        <property type="nucleotide sequence ID" value="XM_001415629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS24"/>
    <dbReference type="STRING" id="436017.A4RS24"/>
    <dbReference type="GeneID" id="4999720"/>
    <dbReference type="KEGG" id="olu:OSTLU_29219"/>
    <dbReference type="eggNOG" id="KOG4020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1663658_0_0_1"/>
    <dbReference type="OrthoDB" id="497990at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03115">
        <property type="entry name" value="Anamorsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007785">
        <property type="entry name" value="Anamorsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046408">
        <property type="entry name" value="CIAPIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273:SF14">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05093">
        <property type="entry name" value="CIAPIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0001">2Fe-2S</keyword>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000392340" description="Anamorsin homolog">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal SAM-like domain" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="1">
        <location>
            <begin position="133"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site A" evidence="1">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site B" evidence="1">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 1" evidence="1">
        <location>
            <begin position="219"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 2" evidence="1">
        <location>
            <begin position="230"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="257" mass="26725" checksum="6329CF1D87E35CBF" modified="2010-03-23" version="2">MSVLALDVARDVAAPRRAEILETLRALADGADATTREIASDDDADALERASCDAYFARARDASEARRACARASEKLRAGGALGVVVDDERTATATTEAMVLAGFTTVTREDDGVVRCVKPNWARGTAFALKSRAVRVNATAADAADAWGASAAADDDELIDESALLTELDVNTAPVKYDDCDVGAGKKACKNCTCGRAEAEAAEEATTAASEETFVSACGNCALGDAFRCAGCPYLGQPAFKDQPGTKVELDLGDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS47</accession>
    <name>A4RS47_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415676.1">
        <property type="nucleotide sequence ID" value="XM_001415639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS47"/>
    <dbReference type="GeneID" id="4999780"/>
    <dbReference type="Gramene" id="ABO93968">
        <property type="protein sequence ID" value="ABO93968"/>
        <property type="gene ID" value="OSTLU_29242"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29242"/>
    <dbReference type="HOGENOM" id="CLU_390501_0_0_1"/>
    <dbReference type="OrthoDB" id="10423782at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="707" mass="78233" checksum="56EBF92BB8C9824F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSA0</accession>
    <name>A4RSA0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_92249</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the INSIG family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO94333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSA0"/>
    <dbReference type="STRING" id="436017.A4RSA0"/>
    <dbReference type="GeneID" id="5000026"/>
    <dbReference type="Gramene" id="ABO94333">
        <property type="protein sequence ID" value="ABO94333"/>
        <property type="gene ID" value="OSTLU_92249"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92249"/>
    <dbReference type="eggNOG" id="KOG4363">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_437689_0_0_1"/>
    <dbReference type="OMA" id="IPTWIPW"/>
    <dbReference type="OrthoDB" id="205546at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36774">
        <property type="entry name" value="INSULIN-INDUCED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36774:SF1">
        <property type="entry name" value="INSULIN-INDUCED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="491"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="625" mass="69762" checksum="96283CE8D571B271" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSK0</accession>
    <name>A4RSK0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Urea-proton symporter DUR3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">High-affinity urea active transporter DUR3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Dur3</name>
        <name evidence="12" type="ORF">OSTLU_119678</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">High-affinity urea-proton symporter involved in the active transport of urea across the plasma membrane into root cells. May play an important role in urea uptake by plant cells at low external urea concentrations.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416230.1">
        <property type="nucleotide sequence ID" value="XM_001416193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSK0"/>
    <dbReference type="STRING" id="436017.A4RSK0"/>
    <dbReference type="GeneID" id="5000069"/>
    <dbReference type="Gramene" id="ABO94523">
        <property type="protein sequence ID" value="ABO94523"/>
        <property type="gene ID" value="OSTLU_119678"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119678"/>
    <dbReference type="eggNOG" id="KOG2348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010778_2_1_1"/>
    <dbReference type="OMA" id="LGANWLT"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033219">
        <property type="term" value="F:urea binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1730.10:FF:000006">
        <property type="entry name" value="Urea active transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF4">
        <property type="entry name" value="UREA ACTIVE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="382"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="625"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00059650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00072203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00079542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="709" mass="75614" checksum="7162D731CEEA1BC8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP9</accession>
    <name>A4RSP9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plastid-encoded RNA polymerase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Rpb3</name>
        <name evidence="6" type="ORF">OSTLU_119616</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416207.1">
        <property type="nucleotide sequence ID" value="XM_001416170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP9"/>
    <dbReference type="STRING" id="436017.A4RSP9"/>
    <dbReference type="GeneID" id="5000477"/>
    <dbReference type="Gramene" id="ABO94500">
        <property type="protein sequence ID" value="ABO94500"/>
        <property type="gene ID" value="OSTLU_119616"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119616"/>
    <dbReference type="eggNOG" id="KOG1522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038421_3_0_1"/>
    <dbReference type="OMA" id="DETKFHF"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="5">
        <location>
            <begin position="20"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="318" mass="34677" checksum="CB5BBBF5328B4049" modified="2007-05-15" version="1">MIPGEETGASVTVARLEDETIIFDLKGVDVSLANALRRLMIADVPTVSIDLVEVIENSSVLCDEFLAHRLGLIPLDSTKASELVKPYEYTGDDDTATDVHLELNVRCQSDQTRDVTSDDLISHDERVKPVSFGGTGGGSAKSGGILIAKLRKNQQLSLKCIARKGTGKDHAKWSPVATAVFKYTPLIDINHGLLNSLNGKSQTRILYHNFKRHNAGPEKAAIVESDPSKMFKYDADTDTFTLTSPESCTYDGEVMKKVNELGKPGLIDVRPGLDCFTFIVESTGVLKVEEVVLQAVHILQSKLDTIGVSSCFDKLEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU13</accession>
    <name>A4RU13_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_30460</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416880.1">
        <property type="nucleotide sequence ID" value="XM_001416843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU13"/>
    <dbReference type="STRING" id="436017.A4RU13"/>
    <dbReference type="GeneID" id="5001021"/>
    <dbReference type="Gramene" id="ABO95173">
        <property type="protein sequence ID" value="ABO95173"/>
        <property type="gene ID" value="OSTLU_30460"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30460"/>
    <dbReference type="eggNOG" id="KOG0760">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_3_5_1"/>
    <dbReference type="OMA" id="VWVPIDV"/>
    <dbReference type="OrthoDB" id="276989at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="101"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="201"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="290" mass="30576" checksum="CFB042F52D591D62" modified="2007-05-15" version="1">MSSARARGADPAAASALDGVLADGARGAVSGLAARFLTHPMDTLKARAQVRGARGAVARAEGGRTRAVGLYKGFGAVAALAPLASGAYFVGYESGTRWFGTSASASAATGMWAQALAGVVYTPMDVIKERLQTQDVLGERARMGRYRHWVDAARVIAREEGARGLFRGYWAQNFVWWPWSAAYFAIYERSRVALESSGGEASPMVSAVSATAAATAATTLTHPLDLAKTRLQTMRFETTTSASLREVLRDVFKREGARGLFAGAGARVAAVAPGSAISFGVYETLKQSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU65</accession>
    <name>A4RU65_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_14544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416618.1">
        <property type="nucleotide sequence ID" value="XM_001416581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU65"/>
    <dbReference type="STRING" id="436017.A4RU65"/>
    <dbReference type="GeneID" id="5000560"/>
    <dbReference type="Gramene" id="ABO94911">
        <property type="protein sequence ID" value="ABO94911"/>
        <property type="gene ID" value="OSTLU_14544"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14544"/>
    <dbReference type="eggNOG" id="KOG2945">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_947774_0_0_1"/>
    <dbReference type="OMA" id="EHENNQE"/>
    <dbReference type="OrthoDB" id="10659897at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
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        <property type="entry name" value="AT19571P-RELATED"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="102"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="309"/>
        </location>
    </feature>
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        <location>
            <begin position="20"/>
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        </location>
    </feature>
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        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="309" mass="31885" checksum="F609B1AA2EB1C082" modified="2007-05-15" version="1">MAMSANPFMALDEDAPRAPAPSAKAASAPASKPATKVAAPARSNGGSKAKPAKATREFEGEVIGAEGSKGFHAKGGRGDHKGHSRSARRGGRGEGGEGRQRSRRDFDRRDASGRGHDGHRGGAGKGNWGKAGDELAELGANTVDESETEPEVVDNSSELTFAQAEALKAEKRAALAAQWKRPEAKVLDGSALEGLKLMSGDADDADLDFGGVGVKSKRDRTKNTTSKQKVDVGFRIASTQPADDRDDRDDRRGGRGGRGGRDSGRGGRGGRDSGRGGRGESSRGGRGGGGRGANIKIEDTSAFPTLGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUF5</accession>
    <name>A4RUF5_OSTLU</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">OSTLU_14611</name>
    </gene>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Mamiellophyceae</taxon>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUF5"/>
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    <dbReference type="Gramene" id="ABO95243">
        <property type="protein sequence ID" value="ABO95243"/>
        <property type="gene ID" value="OSTLU_14611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14611"/>
    <dbReference type="HOGENOM" id="CLU_1130629_0_0_1"/>
    <dbReference type="OMA" id="MEMQECS"/>
    <dbReference type="OrthoDB" id="10650297at2759"/>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
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        <location>
            <begin position="197"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="246" mass="26976" checksum="31C0DF76B8FDBCD6" modified="2007-05-15" version="1">MRATSRAPRVAVARAPGARRARARARTPRRRAGDLFDGVFDARDDDDGRPRAAEAAGEDIEDLVAAAEDSPYFNDAFREALAGAQARQRAERAREKEKIDSEVALIMERVKAERAMKAKSAEKKSAEKPAVEEAVEEAAAETAAETAAETAAEAPASAAAAEVEDSAAAIPSSLDADFVRLLERDLMEMQECSKESISDLTNARERVNQSIANEKRQLARLDILLDRVRREARYLRADALRKKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUH9</accession>
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        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="10" type="ORF">OSTLU_8087</name>
    </gene>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Chlorophyta</taxon>
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            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ABO95256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416926.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RUH9"/>
    <dbReference type="GeneID" id="5001009"/>
    <dbReference type="Gramene" id="ABO95256">
        <property type="protein sequence ID" value="ABO95256"/>
        <property type="gene ID" value="OSTLU_8087"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8087"/>
    <dbReference type="eggNOG" id="KOG0724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060837_4_1_1"/>
    <dbReference type="OMA" id="WPITGDD"/>
    <dbReference type="OrthoDB" id="498348at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000009">
        <property type="entry name" value="transcription factor MYB1R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44042">
        <property type="entry name" value="DUPLICATED HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44042:SF67">
        <property type="entry name" value="MYB-LIKE PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="84"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="84"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="8">
        <location>
            <begin position="92"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="158" mass="18458" checksum="024655B6EF7062B9" modified="2007-05-15" version="1" fragment="single">WTFEEDKFFETSLAQYDGSWPITGDDYWGQLQEQMPQKGVHDLKNRFSKLEEDVRNIEAGLVQLPDYDDDSDHHSKAAPKTGEQERRKGVPWTEEEHKLFLLGLNKFGKGDWRSISRNFVISRTPTQVASHAQKYFIRLNSMSKKDNKRRSSIHDITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUV2</accession>
    <name>A4RUV2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA-binding S4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_30752"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="52"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="13588" checksum="233055155907F639" modified="2007-05-15" version="1">MSPALASAAKTINVDDVDDWIVVKDDRSIEKGWGFSLFGKENEATFESAKRKRVDKMLIKHGYAKTRSDVDDMIKDGRVCVGGAPVERESRVLLSALTVDGKAFVPVKRRAGTLDDDDDDDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUY8</accession>
    <name>A4RUY8_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_34494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416713.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RUY8"/>
    <dbReference type="GeneID" id="5000640"/>
    <dbReference type="Gramene" id="ABO95043">
        <property type="protein sequence ID" value="ABO95043"/>
        <property type="gene ID" value="OSTLU_34494"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34494"/>
    <dbReference type="eggNOG" id="KOG3987">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056100_0_0_1"/>
    <dbReference type="OMA" id="PYMHYVE"/>
    <dbReference type="OrthoDB" id="199041at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106370">
        <property type="term" value="F:protein-L-histidine N-pros-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="METL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890">
        <property type="entry name" value="DREV PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890:SF0">
        <property type="entry name" value="PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="329" mass="35839" checksum="ECEF8DA6CADB86A0" modified="2007-05-15" version="1">MSVERARADARSDRARARPRATADALEDLRVRCAHCDAVFAPRALEYGADARRFASETLRDAFDALERDEETNGFLLRGRERGDAAHRGLARACDELRKTMSLTEANATLGRGAMHVFSTKQARALLTSAGAVGEGEGRLRWFLDVGAGCGEVTETLAKNFEKTCATESSRGMAKRLRERGFDVVLESDTIEDVVGDVRRLGEDLDEDGFDVVAALNLCDRIDAPVTLMSQLKRALKPGTGVLILAIVVPFRPFVEGADGTRTKPSETVDAPSSGSWEAGVEALWENLIAPAGFELIRLARVPYISEGDHLFDAYVLDDAVFVLRAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV94</accession>
    <name>A4RV94_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416765.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RV94"/>
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        <property type="gene ID" value="OSTLU_24322"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG0431">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465716_0_0_1"/>
    <dbReference type="OrthoDB" id="1717591at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072318">
        <property type="term" value="P:clathrin coat disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172">
        <property type="entry name" value="AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172:SF19">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="34"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="61549" checksum="6CA17B047FC42276" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVA6</accession>
    <name>A4RVA6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30906</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVA6"/>
    <dbReference type="GeneID" id="5001074"/>
    <dbReference type="Gramene" id="ABO95101">
        <property type="protein sequence ID" value="ABO95101"/>
        <property type="gene ID" value="OSTLU_30906"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30906"/>
    <dbReference type="HOGENOM" id="CLU_051927_0_0_1"/>
    <dbReference type="OMA" id="MCGDEEM"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="303" mass="34505" checksum="17A2062029F305F7" modified="2007-05-15" version="1">MRRYVSSLPQMGDGPAIGLANDARCVEALRDVWDCTEAVADMTTFARQIEDSFALERALDSSLSEDEWRWAVSLVHSRTFRLEDERGRRPTRRALVAGADLINHSSVPEDVNCDWVANDADVFFISATKDVRKGEEFFLSYGEQCDRHFALFYGFLPRRNSFNRVKLFNNGREALDWYRKLCGADAADDIWNRESERVVKMVCDKYGKYTLDKKSGLRRRVIQDLYLGEGCVVSDSMLLLFNEMCGDEEMAIAAIRTRAEELKTKMVSATGKIETGIAVLDAYSQGLVRDYRSRKIDILDAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVH1</accession>
    <name>A4RVH1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_86903</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417135.1">
        <property type="nucleotide sequence ID" value="XM_001417098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVH1"/>
    <dbReference type="STRING" id="436017.A4RVH1"/>
    <dbReference type="GeneID" id="5001183"/>
    <dbReference type="Gramene" id="ABO95428">
        <property type="protein sequence ID" value="ABO95428"/>
        <property type="gene ID" value="OSTLU_86903"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86903"/>
    <dbReference type="eggNOG" id="KOG1354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021713_3_3_1"/>
    <dbReference type="OMA" id="NQIKWCR"/>
    <dbReference type="OrthoDB" id="6274823at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000609">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018067">
        <property type="entry name" value="PP2A_PR55_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11871">
        <property type="entry name" value="PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037309">
        <property type="entry name" value="PP2A_PR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01024">
        <property type="entry name" value="PR55_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU331113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="513" mass="57098" checksum="E91C11677E183595" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVS7</accession>
    <name>A4RVS7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS family transporter: glycerol-3-phosphate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31082</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417462.1">
        <property type="nucleotide sequence ID" value="XM_001417425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVS7"/>
    <dbReference type="GeneID" id="5001628"/>
    <dbReference type="Gramene" id="ABO95755">
        <property type="protein sequence ID" value="ABO95755"/>
        <property type="gene ID" value="OSTLU_31082"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31082"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_589739_0_0_1"/>
    <dbReference type="OMA" id="SCAFART"/>
    <dbReference type="OrthoDB" id="431005at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055062">
        <property type="term" value="P:phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000849">
        <property type="entry name" value="Sugar_P_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43184">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43184:SF12">
        <property type="entry name" value="SUGAR PHOSPHATE EXCHANGER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002808">
        <property type="entry name" value="Hexose_phosphate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="22"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="464" mass="50206" checksum="8E051AF051AE7A86" modified="2007-05-15" version="1">MGVASDIGAMRVVRPMSKRDRTSWMTVVVSFVNFTSFHAVREGYMACKSTLHDRAKYPTVLLGEIDFGFCASYACGLFTAGYLGRKYGVRKTIAISFLLTGLLSIAFGAVIGYALAPKSEDEAWTVAWTAHVPLWMASAFVQGWTYPNFIALLSDSIEPYFRATVLTVWATASPVGDIVGLQIAQAVLREGEEHWPYVMFVAGVFVLLNLVLFLVCIGANKARIVRDEEDEDEEEASLLDAPPVSETVEDESPQAGFWRVMSDVSKIPGVLDYAFSVMALKVVVTSLLFWIPYYVEERFDSHSSSIVSTQFFDLSLILGMGFAALLNRLIGRWVLLFLVSLVLGLVPLLAIPYSKTLGGTVSCIFLAGFLIGPAAALFAGVMSAEVGKKAKIHSDRGGIIGIISGLIDSAGAIGSGTGQILVGALASTYGWHTVFKVLAGFVGIGAISLVRVRRMENEEASTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVW0</accession>
    <name>A4RVW0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribosomal protein L8, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPL8</name>
        <name evidence="8" type="ORF">OSTLU_31116</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417217.1">
        <property type="nucleotide sequence ID" value="XM_001417180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVW0"/>
    <dbReference type="STRING" id="436017.A4RVW0"/>
    <dbReference type="GeneID" id="5001321"/>
    <dbReference type="Gramene" id="ABO95510">
        <property type="protein sequence ID" value="ABO95510"/>
        <property type="gene ID" value="OSTLU_31116"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31116"/>
    <dbReference type="eggNOG" id="KOG2309">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036235_0_3_1"/>
    <dbReference type="OMA" id="GGRHPCT"/>
    <dbReference type="OrthoDB" id="585154at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000020">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000006">
        <property type="entry name" value="60S ribosomal protein L8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023672">
        <property type="entry name" value="Ribosomal_uL2_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007180">
        <property type="entry name" value="PRK09612.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="7">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="6">
        <location>
            <begin position="96"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="255" mass="27470" checksum="9AA6671C22104A8F" modified="2007-05-15" version="1">MGRVIRGCRKGKGSVFTSHTHTRKGAAKHRQQDYAERHGYVKGVVTDIIHDPGRGAPLAKMTFRHTKRYGLQKELFIAAEGTYTGQFVYAGKKAQLAIGNILPISSMPEGTIICNVESKLGDRGTLAKASGEYCILISHNLDTGFSRIKLPSGAKKTIPSGCRATVGQVSGGGRCDKPMLKAGASYHKYKVKRNSWPKVRGVAMNPVEHPHGGGNHQHIGHASTIRRDRSAGAKVGLIAARRTGRLRGAKPSEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVX3</accession>
    <name>A4RVX3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_31131</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">The Mn(2+) ion enhances activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417485.1">
        <property type="nucleotide sequence ID" value="XM_001417448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVX3"/>
    <dbReference type="GeneID" id="5001178"/>
    <dbReference type="Gramene" id="ABO95778">
        <property type="protein sequence ID" value="ABO95778"/>
        <property type="gene ID" value="OSTLU_31131"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31131"/>
    <dbReference type="eggNOG" id="ENOG502QQEM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_1_1_1"/>
    <dbReference type="OMA" id="PGFFVWM"/>
    <dbReference type="OrthoDB" id="6119954at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010211">
        <property type="term" value="F:IAA-Leu conjugate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010210">
        <property type="term" value="F:IAA-Phe conjugate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009850">
        <property type="term" value="P:auxin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd08017">
        <property type="entry name" value="M20_IAA_Hyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000001">
        <property type="entry name" value="N-acetyldiaminopimelate deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044757">
        <property type="entry name" value="ILR1-like_Hyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014:SF63">
        <property type="entry name" value="METALLOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PEPTIDASE M20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673024" description="Peptidase M20 dimerisation domain-containing protein" evidence="5">
        <location>
            <begin position="17"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="6">
        <location>
            <begin position="226"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005962-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="443" mass="47080" checksum="097264EC01885F58" modified="2007-05-15" version="1">MLRALFFLAHVPAALALDATTLRDIAASSSNVDAREILSQSRATHDYVVDLRREIHKNPELMWTERATADVIARELDAHGIEYDRVTSTGIVARVGRGERSVGLRADMDALPLREDTGLAYASENDGKMHACGHDGHVAMLLGAAKVIKARYDADETSVPGVVRFIFQPAEEGGAGAKEMLRPSDGTTGMLDLKPPIESVFGLHNWPYPEMPSGTMGTRGGTIMAGAGSFDVVVVGRGGHAAVPHNNVDVIVAGSAIVTALQTLVSRLTDPLDSVVISVTVFNSGTASNIMPDTASLQGTLRALNPKTFAKFQQKIADMASAIASAHGCTAATSFEPEHNGVKRIPYPPTVNDPRAAGLAMNVAAQLFGSESTRDVVPVMPAEDFSFFGETYPSAMMWLGAYNETAGATHPLHSTKYILDESVLTSGVALHAMYALEFLHSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVX9</accession>
    <name>A4RVX9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">signal peptidase I</fullName>
            <ecNumber evidence="3">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_5885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417227.1">
        <property type="nucleotide sequence ID" value="XM_001417190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVX9"/>
    <dbReference type="STRING" id="436017.A4RVX9"/>
    <dbReference type="MEROPS" id="S26.A02"/>
    <dbReference type="GeneID" id="5001389"/>
    <dbReference type="Gramene" id="ABO95520">
        <property type="protein sequence ID" value="ABO95520"/>
        <property type="gene ID" value="OSTLU_5885"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5885"/>
    <dbReference type="eggNOG" id="KOG0171">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_5_1_1"/>
    <dbReference type="OMA" id="GRACFKY"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009003">
        <property type="term" value="F:signal peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390:SF1">
        <property type="entry name" value="CHLOROPLAST PROCESSING PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="SIGNAL PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="6">
        <location>
            <begin position="35"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="199" mass="22290" checksum="C88F9F892C5BF0C2" modified="2007-05-15" version="1" fragment="single">GGGGSSDGDGDDEYVVDVDYPEWVPEFLRFNREDIATVLITFAVSLGFRHFVAEPRYIPSLSMYPVFDVGDRLIAEKLTYRFNREPMAGDVVIFNPPKTPKTMKVSNEVFIKRVVAVAGDTVQVKRGELFVNGVSRGKELKLEPIKYQYGPFTVPEGDVFVMGDNRNNSFDSHVWGPLPKNRIIGRATAKYWPPNKIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVY5</accession>
    <name>A4RVY5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Exoribonuclease phosphorolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_92599</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417490.1">
        <property type="nucleotide sequence ID" value="XM_001417453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVY5"/>
    <dbReference type="STRING" id="436017.A4RVY5"/>
    <dbReference type="GeneID" id="5001393"/>
    <dbReference type="Gramene" id="ABO95783">
        <property type="protein sequence ID" value="ABO95783"/>
        <property type="gene ID" value="OSTLU_92599"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92599"/>
    <dbReference type="eggNOG" id="KOG1068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063514_0_0_1"/>
    <dbReference type="OMA" id="MCCVYGP"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11371">
        <property type="entry name" value="RNase_PH_MTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF2">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT MTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="9">
        <location>
            <begin position="17"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
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            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417890.1">
        <property type="nucleotide sequence ID" value="XM_001417853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWV6"/>
    <dbReference type="GeneID" id="5002056"/>
    <dbReference type="Gramene" id="ABO96183">
        <property type="protein sequence ID" value="ABO96183"/>
        <property type="gene ID" value="OSTLU_31472"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31472"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016265_1_1_1"/>
    <dbReference type="OMA" id="GMDTQLE"/>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="98"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="4">
        <location>
            <begin position="226"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="54831" checksum="E699BEB4113BA30A" modified="2007-05-15" version="1">MVGAANATHMLTNARATAPAGARSARRARVFARADVAVRAAPTSTGRARDGRARGALAVTRERASAVDGKRRRSAQTIGAVANPLAVPTYDAPEGRDKNEPIRVKIGDEWYDCRGWAKAHPGGERWLYFFDGRDATDVFYALHSYGPNGSDLAVQRLKKLPRCDPPADKSRLPDEKSYAVSMAFGELRDKLAEDGFFKRQPLKEAWALFQVVALYVSGTALAYSHPVWATILLGLGMEQAGWLGHDYVHGRGPWCSLMRYMPTILNGHSVEWWMQKHSMHHSFTNEEHLDNDVMMEPFFFLRSPQESGRPDHPMRKFQHIYGYPLLSIMFWLWRFHSVQTAWKKRDYKELAFIGANYLFLATMMPWQVAVGSITLSGFLVGALVSATHQSEEIMEFGENPEYVEGQFRSTRDAECVFGGLETWIWGGMDTQLEHHLFPTMPRYNYHKLRPLLKAWAKANGVTYRSSPSTEIIADNFKMLHRVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX20</accession>
    <name>A4RX20_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_31537</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417920.1">
        <property type="nucleotide sequence ID" value="XM_001417883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX20"/>
    <dbReference type="STRING" id="436017.A4RX20"/>
    <dbReference type="GeneID" id="5001678"/>
    <dbReference type="Gramene" id="ABO96213">
        <property type="protein sequence ID" value="ABO96213"/>
        <property type="gene ID" value="OSTLU_31537"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31537"/>
    <dbReference type="eggNOG" id="KOG3503">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_184680_1_0_1"/>
    <dbReference type="OMA" id="AEYYINE"/>
    <dbReference type="OrthoDB" id="13807at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904874">
        <property type="term" value="P:positive regulation of telomerase RNA localization to Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.40:FF:000002">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.40">
        <property type="entry name" value="H/ACA ribonucleoprotein complex, subunit Nop10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="Nop10-like SnoRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="61" mass="7077" checksum="C0D00C2F5342B407" modified="2007-05-15" version="1">MYYMNEKGERVYTLKKTAPDGTPTQSAHPARFSPDDKFSKQRVALKKRFSLLPTQQPEVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX28</accession>
    <name>A4RX28_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417682.1">
        <property type="nucleotide sequence ID" value="XM_001417645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX28"/>
    <dbReference type="GeneID" id="5001683"/>
    <dbReference type="Gramene" id="ABO95975">
        <property type="protein sequence ID" value="ABO95975"/>
        <property type="gene ID" value="OSTLU_31545"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31545"/>
    <dbReference type="HOGENOM" id="CLU_2324537_0_0_1"/>
    <dbReference type="OrthoDB" id="566239at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="99" mass="10705" checksum="CA5FDBAC433C614D" modified="2007-05-15" version="1">MRESARDNRRGGFALTTRASKDDRPTKASEELAEKFTTGGGGADGFCDYDDIKDAIKECEGLEGAKLEACYAQYGCNLESVTEHYAKAAGIDSKNEKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXF8</accession>
    <name>A4RXF8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_31680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417993.1">
        <property type="nucleotide sequence ID" value="XM_001417956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXF8"/>
    <dbReference type="STRING" id="436017.A4RXF8"/>
    <dbReference type="GeneID" id="5001837"/>
    <dbReference type="Gramene" id="ABO96286">
        <property type="protein sequence ID" value="ABO96286"/>
        <property type="gene ID" value="OSTLU_31680"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31680"/>
    <dbReference type="eggNOG" id="KOG2289">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1039727_0_0_1"/>
    <dbReference type="OMA" id="ACTNAIM"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019374">
        <property type="term" value="P:galactolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF26">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN 10, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="8">
        <location>
            <begin position="87"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="268" mass="28260" checksum="EB472E4A5E9EAF74" modified="2007-05-15" version="1">MVGKAANAVALGAALAGPGERADGARGGGRRREGGRRAAARGVFDDPDRACTNAIMIGTASAFALQILSGQAITALGAKVNERIAAGQLWRLATPIFLHGGLPHLMVNMYSLNSIGPLMEATFGREQFLAVYFGAGVAGNYASYRFCASNSVGASGAVFGLAGALAVYLQRHKRYLGERADMQLQQLGTALAVNMGFGLTSRRIDNWGHAGGLVGGAALAFLTGPNLVMETDGGYGLRRKLVNKPKLQSTIRAIKDFWDEDDEDEDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYH3</accession>
    <name>A4RYH3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418390.1">
        <property type="nucleotide sequence ID" value="XM_001418353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYH3"/>
    <dbReference type="GeneID" id="5002270"/>
    <dbReference type="Gramene" id="ABO96683">
        <property type="protein sequence ID" value="ABO96683"/>
        <property type="gene ID" value="OSTLU_32028"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32028"/>
    <dbReference type="HOGENOM" id="CLU_2113000_0_0_1"/>
    <dbReference type="OMA" id="TPSARCE"/>
    <dbReference type="OrthoDB" id="10516949at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="entry name" value="Large-conductance mechanosensitive channel, MscL, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="115" mass="12196" checksum="09EF478530EB1852" modified="2007-05-15" version="1">MVEEVLDAFIDAFVSPSVALMLGSRSKALEEMAFVCGGATFRYGALLARIIDACLTLALIYATMRAVAKISIAGAPAWTPSARCGLCKSWVSADARVCPACRRAISDDDDDDDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYN4</accession>
    <name>A4RYN4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418421.1">
        <property type="nucleotide sequence ID" value="XM_001418384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYN4"/>
    <dbReference type="GeneID" id="5002175"/>
    <dbReference type="Gramene" id="ABO96714">
        <property type="protein sequence ID" value="ABO96714"/>
        <property type="gene ID" value="OSTLU_94480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94480"/>
    <dbReference type="HOGENOM" id="CLU_2762381_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="70" mass="8066" checksum="9D6AA92CB791A074" modified="2007-05-15" version="1">MSLPESSLRLLRMFFSNQSQCDAITGESVLRTFSLAERGKWMSLLYASLSVPVYLATFYFGVSRVRHEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYP7</accession>
    <name>A4RYP7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418200.1">
        <property type="nucleotide sequence ID" value="XM_001418163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYP7"/>
    <dbReference type="GeneID" id="5002562"/>
    <dbReference type="Gramene" id="ABO96493">
        <property type="protein sequence ID" value="ABO96493"/>
        <property type="gene ID" value="OSTLU_92876"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92876"/>
    <dbReference type="HOGENOM" id="CLU_736484_0_0_1"/>
    <dbReference type="OMA" id="HIVLEAC"/>
    <dbReference type="OrthoDB" id="10398412at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038925">
        <property type="entry name" value="At3g17800-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008479">
        <property type="entry name" value="DUF760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31808">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31808:SF4">
        <property type="entry name" value="LIGASE, PUTATIVE (DUF760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05542">
        <property type="entry name" value="DUF760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="376" mass="40873" checksum="B289B04EC00F4A36" modified="2007-05-15" version="1">MRDGGDRGDDGGEATRAIGIECRTSAGDRLRETLAREGGRGFERDARRALRELVAMGYTAGEGAESAECDRDCVIGRAAMTRMEVEDIMYLSAAREVVRAGGGGGEASDARESAADDGRGRLRLMHRCQRLQELLPKGSDEFMINLVLRVIDNVSKHSHKVGLTHAVKTSTLADVYSKCASFGYFLQASERRLELEHFVSTNVDFVHLEKLAYPKKLARYGVLRSGLKALEGSTPSAVASRVAGYEVPVPLRVPGGIQIQNDMVSLKEYIDEMGPSARAHAARIASVEATEVLQLHVASLFAGDRGRVLTSLGQFRRKPHRNGGNDTADEQRVSVHVNQLKHIVLEACAFGATLAKIEASIDCESIESSKPLLTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYW7</accession>
    <name>A4RYW7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GCK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418466.1">
        <property type="nucleotide sequence ID" value="XM_001418429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYW7"/>
    <dbReference type="GeneID" id="5002388"/>
    <dbReference type="Gramene" id="ABO96759">
        <property type="protein sequence ID" value="ABO96759"/>
        <property type="gene ID" value="OSTLU_32169"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32169"/>
    <dbReference type="eggNOG" id="ENOG502S7G4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1809431_0_0_1"/>
    <dbReference type="OMA" id="STVWIDP"/>
    <dbReference type="OrthoDB" id="2148418at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012891">
        <property type="entry name" value="GCK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34357:SF2">
        <property type="entry name" value="F26F24.3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34357">
        <property type="entry name" value="F7A19.14 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07802">
        <property type="entry name" value="GCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01227">
        <property type="entry name" value="GCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GCK" evidence="2">
        <location>
            <begin position="29"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="143" mass="15149" checksum="B284B20D454AD613" modified="2007-05-15" version="1">MATATAPAGDASDAPRASDARDEDEEEEETCGFCKYMKGGSCRAAFAAWEACVDAAKARDEDFVETCFETTSALRECMLRDPEYYGPMTGEEGERAEGAAEAEAEAETETEAEAEAEAEARARAAAADAREVAVEAEARARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ42</accession>
    <name>A4RZ42_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">starch synthase</fullName>
            <ecNumber evidence="4">2.4.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_41260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="4"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418264.1">
        <property type="nucleotide sequence ID" value="XM_001418227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ42"/>
    <dbReference type="STRING" id="436017.A4RZ42"/>
    <dbReference type="CAZy" id="CBM53">
        <property type="family name" value="Carbohydrate-Binding Module Family 53"/>
    </dbReference>
    <dbReference type="CAZy" id="GT5">
        <property type="family name" value="Glycosyltransferase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="5002596"/>
    <dbReference type="Gramene" id="ABO96557">
        <property type="protein sequence ID" value="ABO96557"/>
        <property type="gene ID" value="OSTLU_41260"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41260"/>
    <dbReference type="eggNOG" id="ENOG502QQTU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_18_3_1"/>
    <dbReference type="OMA" id="SCDIATT"/>
    <dbReference type="OrthoDB" id="2018403at2759"/>
    <dbReference type="UniPathway" id="UPA00152"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005085">
        <property type="entry name" value="CBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46083">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46083:SF5">
        <property type="entry name" value="STARCH SYNTHASE 3, CHLOROPLASTIC_AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16760">
        <property type="entry name" value="CBM53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01066">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="8">
        <location>
            <begin position="130"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="677" mass="75157" checksum="D74D9E5E4BAE481C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ60</accession>
    <name>A4RZ60_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Amt family transporter: ammonium</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_45928</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO96813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418483.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RZ60"/>
    <dbReference type="GeneID" id="5002482"/>
    <dbReference type="Gramene" id="ABO96813">
        <property type="protein sequence ID" value="ABO96813"/>
        <property type="gene ID" value="OSTLU_45928"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45928"/>
    <dbReference type="eggNOG" id="KOG0682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_1_1"/>
    <dbReference type="OMA" id="YTEFQTT"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097272">
        <property type="term" value="P:ammonium homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730:SF116">
        <property type="entry name" value="PROTEIN-SERINE_THREONINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="2"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="465"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="517" mass="54468" checksum="0AF18EE18E2F4FAD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ77</accession>
    <name>A4RZ77_OSTLU</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418244.1"/>
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        <property type="gene ID" value="OSTLU_92928"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="544" mass="61940" checksum="95A65BB6E5E5C369" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZH7</accession>
    <name>A4RZH7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Gramene" id="ABO96866">
        <property type="protein sequence ID" value="ABO96866"/>
        <property type="gene ID" value="OSTLU_32390"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32390"/>
    <dbReference type="HOGENOM" id="CLU_1087378_0_0_1"/>
    <dbReference type="OrthoDB" id="498765at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="194"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="27521" checksum="CE18EED5EB00A6D6" modified="2007-05-15" version="1">MSSSLAFPDRARSNSHAGSRLAQCPLCSKFAHVALIEAHAAQCSGDATVGVERSRALEAGRNASASDAADAEATDALTSCEASTTVKSSGGVLGALAAAKRRNEHAQTRAQNDFKRRRQTTGLLSDVTNAPLVKRSDGGVKSSVVNASTQTDAVVEKEEEETMDVDAAVADVEGVAPSSVQFDLRVMSGNHEECGICLTQFDDAEGVVRHMFYPCQHVRQCGDCAQRVWQVPKVKRRCPWCKSKIEIRPRAFKPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZS6</accession>
    <name>A4RZS6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A4RZS6"/>
    <dbReference type="GeneID" id="5003052"/>
    <dbReference type="Gramene" id="ABO96914">
        <property type="protein sequence ID" value="ABO96914"/>
        <property type="gene ID" value="OSTLU_16028"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16028"/>
    <dbReference type="HOGENOM" id="CLU_687621_0_0_1"/>
    <dbReference type="OMA" id="MGCRGHG"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100">
        <property type="entry name" value="IMP2'P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100:SF4">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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            <begin position="40"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="239"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="401" mass="44279" checksum="DC9F8062C595FD95" modified="2007-05-15" version="1">MEGMGDEAERGANAATIEPAREARAKKRILLLLSGAQMQDVKMVEFARAFALEPNDDVWCVHYSRGATRYASAMYGPGRVAGSYKADEDSVTERLGVRVVPLRRDDAEGAESERESSWLPEYVRAELLDRRLSGKSFVQAVEISGSSGKFSVEEAVQAIVDGEFASAENDNWVCIPKPDLIVMGCRGHGLVRRALLGSVTQNVLNRIPVSTLFFRSSLPKIVGASDLVKQKLGGVDQRVVCICMSGSNSSRRLCEYFVKEHIRSTDVVLLLHCLAESQRKQKDLSEADVEENLSRSYDLVQNFQKEHPGHGRVIRMVLQKETGSASDIRDRTIDFLNMTDVNLAVVGRAISSGHLRSRFMSPYPQYCVTHAPCPVLVWNPPPSYIRSQSQTSAAEKSTVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZS7</accession>
    <name>A4RZS7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418850.1">
        <property type="nucleotide sequence ID" value="XM_001418813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZS7"/>
    <dbReference type="GeneID" id="5002676"/>
    <dbReference type="Gramene" id="ABO97143">
        <property type="protein sequence ID" value="ABO97143"/>
        <property type="gene ID" value="OSTLU_32491"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32491"/>
    <dbReference type="HOGENOM" id="CLU_832586_0_0_1"/>
    <dbReference type="OMA" id="SSGVEWW"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="334" mass="36457" checksum="09EE256CEB31FDA3" modified="2007-05-15" version="1">MPRDDDDDDAFCVVLDARGRVHGAAIDGDEGAYFATRARDAFARTAAHRARLADSCRKIDALGTLWLGARDAPRCALERFVKSVYDAHARGVTRDDARSGVEFWARTRATAAHWDKDERAREIAGVCVTPHVSTVTYVEVEESARVAPTVVFEGLTARGRPDAEARDEAGARCERAAVMIPKAGAHFKFDGRFLHGVFDEFASGDVDASAARVTLLANIWFDHVPVGVERLDESLAATLGDDESCVANEAATEMTTRTIASSEFATTPMKDVAFGPSGGEYELVGAEFPFDELRESAKGEEGEERVHLFFITNEAGVRIKLRDDDEPASKRVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZY3</accession>
    <name>A4RZY3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418879.1">
        <property type="nucleotide sequence ID" value="XM_001418842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZY3"/>
    <dbReference type="STRING" id="436017.A4RZY3"/>
    <dbReference type="GeneID" id="5002812"/>
    <dbReference type="Gramene" id="ABO97172">
        <property type="protein sequence ID" value="ABO97172"/>
        <property type="gene ID" value="OSTLU_32554"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32554"/>
    <dbReference type="eggNOG" id="ENOG502QPT0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425429_0_0_1"/>
    <dbReference type="OrthoDB" id="1907605at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010564">
        <property type="term" value="P:regulation of cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039893">
        <property type="entry name" value="CEP120-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21574">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 120 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21574:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 120 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="206"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="443"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="644" mass="71526" checksum="01D9A351489BC5B3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0F5</accession>
    <name>A4S0F5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418963.1">
        <property type="nucleotide sequence ID" value="XM_001418926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0F5"/>
    <dbReference type="GeneID" id="5002905"/>
    <dbReference type="Gramene" id="ABO97256">
        <property type="protein sequence ID" value="ABO97256"/>
        <property type="gene ID" value="OSTLU_32726"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32726"/>
    <dbReference type="HOGENOM" id="CLU_2594134_0_0_1"/>
    <dbReference type="OMA" id="WNTFCEF"/>
    <dbReference type="OrthoDB" id="10383429at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673004" evidence="1">
        <location>
            <begin position="22"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="80" mass="8732" checksum="4928FF7B65C5386D" modified="2007-05-15" version="1">MSTQLQLRLAVICALCTLAHAATNEPRRALVESSITYAADTTGISRGQSISTSTTWNTFCEFILPFLLERGYTPPAHVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S121</accession>
    <name>A4S121_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_9955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419286.1">
        <property type="nucleotide sequence ID" value="XM_001419249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S121"/>
    <dbReference type="STRING" id="436017.A4S121"/>
    <dbReference type="GeneID" id="5003340"/>
    <dbReference type="Gramene" id="ABO97579">
        <property type="protein sequence ID" value="ABO97579"/>
        <property type="gene ID" value="OSTLU_9955"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9955"/>
    <dbReference type="HOGENOM" id="CLU_2968005_0_0_1"/>
    <dbReference type="OMA" id="GELCEDM"/>
    <dbReference type="OrthoDB" id="31183at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040191">
        <property type="entry name" value="UTP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457">
        <property type="entry name" value="BAP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="59" mass="6718" checksum="1B83DB19D1CDD189" modified="2007-05-15" version="1" fragment="single">VLSIMTIEQIVDKLQEEYLQLLPEAIPFLGELCEDMEPEIENLSRALTKKLSKLSGEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1H4</accession>
    <name>A4S1H4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein HGH1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_42650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419148.1">
        <property type="nucleotide sequence ID" value="XM_001419111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1H4"/>
    <dbReference type="STRING" id="436017.A4S1H4"/>
    <dbReference type="GeneID" id="5003473"/>
    <dbReference type="Gramene" id="ABO97441">
        <property type="protein sequence ID" value="ABO97441"/>
        <property type="gene ID" value="OSTLU_42650"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42650"/>
    <dbReference type="eggNOG" id="KOG2973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037769_0_0_1"/>
    <dbReference type="OMA" id="NWPWAGE"/>
    <dbReference type="OrthoDB" id="338814at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039717">
        <property type="entry name" value="Hgh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007205">
        <property type="entry name" value="Protein_HGH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387:SF9">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04063">
        <property type="entry name" value="DUF383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein HGH1 N-terminal" evidence="1">
        <location>
            <begin position="104"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="349" mass="37146" checksum="4B2351F0545F6F7F" modified="2007-05-15" version="1">MADELDEVIGFLSDKNPAVREQAAHIIQGLTGTDDGAKLLCAKADSLVPKLLHALGKEGAESKYAATALVNLTHDPEVIVKAVNKGVVERAMDGLRDGDGAPVDLLLSILANVTTAESGVHVISQEGKPLEGFYVSKLIQLLSTGKPEEDYDHAASVLTNISRDPIGRRVFLDPKRGLLASVVSIMSESNDLRRERVAAALRNCCMDDIQRKALLDFVSPGAQEAAGDVLRALLRPISGKQVGAELSDHVRQACAEAIYALAKDEEGRMWLGKLDAPRTLRDGYELEEHAETCAALVAAGDLFLKHGMVPEDLQEGLNQPQAVEVIDDDEAVVMMGPGVGGGGFISGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1J4</accession>
    <name>A4S1J4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_33121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419158.1">
        <property type="nucleotide sequence ID" value="XM_001419121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1J4"/>
    <dbReference type="STRING" id="436017.A4S1J4"/>
    <dbReference type="GeneID" id="5003216"/>
    <dbReference type="Gramene" id="ABO97451">
        <property type="protein sequence ID" value="ABO97451"/>
        <property type="gene ID" value="OSTLU_33121"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33121"/>
    <dbReference type="eggNOG" id="KOG1368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029381_0_1_1"/>
    <dbReference type="OMA" id="VQTNIVI"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="368" mass="39734" checksum="36F26AB1EA00DB3D" modified="2007-05-15" version="1">MRLSDGVVDARSDTVTKPTARMREAMARAEVGDDVLGDDRTVKALERKMAEMFGFEAAVFTPSGTMANLLAIATWCDERGSEAIIGDKSHVHLYEQGGMSSLMGVHSRTLKNREDGTLALEDIRAAIRTVSDDHFPVTKVVTLENTQNKCGGKVLPVEYVREVGALCAAHGVKLHMDGARIWNALAASIDHVRIDHILQGCDSASICLSKAIGAPVGSVLLGDEAFVRKAKRLRKALGGSMRQVGVLAAAALEAIDEVFPKIAEDHERARAFANALQGATGLECATPESNLVLVRSTIPGITSEMLMRELEMSHGVLVLPTNQDTIRVAFHHQITDAGVERLVSGFRESVLELARDPKLNEIMMSDGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1P6</accession>
    <name>A4S1P6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_42380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419184.1">
        <property type="nucleotide sequence ID" value="XM_001419147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1P6"/>
    <dbReference type="STRING" id="436017.A4S1P6"/>
    <dbReference type="GeneID" id="5003161"/>
    <dbReference type="Gramene" id="ABO97477">
        <property type="protein sequence ID" value="ABO97477"/>
        <property type="gene ID" value="OSTLU_42380"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42380"/>
    <dbReference type="eggNOG" id="KOG1802">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001666_0_0_1"/>
    <dbReference type="OrthoDB" id="498135at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF517">
        <property type="entry name" value="RNA HELICASE NONSENSE MRNA REDUCING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="6">
        <location>
            <begin position="66"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="7">
        <location>
            <begin position="151"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="426"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="51969" checksum="1530F1B50010FB87" modified="2007-05-15" version="1">MWLRCRTSPILCTSDSNIAVDNLVDGLARAGVRVARIGRPEAVRQDLMPYMIESIAGIDQDCRWSKQQQRSAITNALRQAEVICATCAGAGSDILEKYSFQACLIDEATQATEPATVIPLTKGCKQVVLIGDQNQLPPTIISREAEAAGLGESLFERFIRAGIRTYMLKVQYRMHPAIALFPSKTFYKGELLSGTPPSQRRAPVGFDWPVPAVPMAFVNVEEGAERSDGSSQTNPAEIQRVVNIVKKLAGQHEVLPGDIGVVTPYSAQARAIKKILRGNAPERTRFDAPADPTSMKAVEVATVDGFQGREKEVIVFSCTRANMNGNVGFLADTRRVNVMLTRAKRGLIIVGHMKTLQQDEIVWKGWLKWARESGLICGLSATDSDAANRLASIGMSAANEIGGTGIGQTYIQNALGKPVSWATGQLKESTSQPKLAERDVIPDAWDDSDDEENISTQGVNTITSVSSMTGMADEAWDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1S7</accession>
    <name>A4S1S7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_42544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419419.1">
        <property type="nucleotide sequence ID" value="XM_001419382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1S7"/>
    <dbReference type="STRING" id="436017.A4S1S7"/>
    <dbReference type="GeneID" id="5003114"/>
    <dbReference type="Gramene" id="ABO97712">
        <property type="protein sequence ID" value="ABO97712"/>
        <property type="gene ID" value="OSTLU_42544"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42544"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016785_4_0_1"/>
    <dbReference type="OMA" id="PYRNICK"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02208">
        <property type="entry name" value="cupin_RmlC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF104">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="26"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="239" mass="26798" checksum="CB91F17EE2CF0A81" modified="2007-05-15" version="1">MAFGEFLDRVSERAGREPLIGEGERYYLRSVDGKARADVRRTHPGLARALELECVWPETRFHSSVLRISSSETTLQTHFDTHDNVLIQLAGEKEVTLFPPEVDSYMYVQGSSSRVNYPNDAPGEFPLFDKYAKDAALKIKLRPGDALFIPAFWFHHVYASGDGASVAVNVFFRTFEPSAYNPSDIYGNKDLVAGKEACDLASRAGSALDELPEPFRSFYARRAVKALANQLAVRINEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1W3</accession>
    <name>A4S1W3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Limiting CO2-inducible protein B/C beta carbonyic anhydrase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">LCI1</name>
        <name evidence="2" type="ORF">OSTLU_33242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419219.1">
        <property type="nucleotide sequence ID" value="XM_001419182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1W3"/>
    <dbReference type="SMR" id="A4S1W3"/>
    <dbReference type="STRING" id="436017.A4S1W3"/>
    <dbReference type="GeneID" id="5003134"/>
    <dbReference type="Gramene" id="ABO97512">
        <property type="protein sequence ID" value="ABO97512"/>
        <property type="gene ID" value="OSTLU_33242"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33242"/>
    <dbReference type="eggNOG" id="ENOG502RYX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071940_0_0_1"/>
    <dbReference type="OMA" id="PSMEFIA"/>
    <dbReference type="OrthoDB" id="2014244at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040703">
        <property type="entry name" value="LCIB/C_CA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38016:SF1">
        <property type="entry name" value="LIMITING CO2-INDUCIBLE PROTEIN B_C BETA CARBONYIC ANHYDRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38016">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18599">
        <property type="entry name" value="LCIB_C_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Limiting CO2-inducible protein B/C beta carbonyic anhydrase" evidence="1">
        <location>
            <begin position="55"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="334" mass="36871" checksum="3F361EFF53CA7CC6" modified="2007-05-15" version="1">MPRAQGPMRGQHPVAPHGPRFHEYGGFDIDPELQHSRVSYLRERVEAVTKEFPNAIGMDDFLFRTEVMLRRFGFTTDNSIALTSLCRDEITFPLKNAIDDIFGYSMDLDGLGGIISAGTTGLGAGLSHSPTDHLTGKERYVLFAMPHIAIDAEGRVGSIVRAGRRGQSCACGALVKMQPMFKQYKEGTLEMGLDEGGHDPLDPEFSILTRRLITAVNKDEIPDKGLPLSDVTRLADRVIRRDLDKLIGETVDVTKSDYAVVTGIQIHSTAANNRTWHPALEFISPTSMYVVKDGVRHDMDVLAIDPPTPRQLFHIAGGEEIAELPSPRRSWPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S231</accession>
    <name>A4S231_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HVA22-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419465.1">
        <property type="nucleotide sequence ID" value="XM_001419428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S231"/>
    <dbReference type="STRING" id="436017.A4S231"/>
    <dbReference type="GeneID" id="5003795"/>
    <dbReference type="Gramene" id="ABO97758">
        <property type="protein sequence ID" value="ABO97758"/>
        <property type="gene ID" value="OSTLU_94638"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94638"/>
    <dbReference type="eggNOG" id="KOG1726">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1613564_0_0_1"/>
    <dbReference type="OMA" id="TINIWYI"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18069" checksum="E2DA39719AD49C0B" modified="2007-05-15" version="1">MLGLGLKIAGFGVGYCYPTYSALKLLDRKVIGPEDVTLWLTYFMIAFTLAIGEAIGVVGWIPAYRIMKVLFCAWMVNPRFKGAITLYKKGIQPIFHQLSPSIDKHAENLKKGDFAAIQQELGPQFAKVQELVKKHGPEAIERAMNLAGKGDKKNAATAANGTKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S256</accession>
    <name>A4S256_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DMT family transporter: CMP-sialic acid/UDP-N-acetylglucosamine</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_50402</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. CMP-Sialate:CMP antiporter (TC 2.A.7.12) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419689.1">
        <property type="nucleotide sequence ID" value="XM_001419652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S256"/>
    <dbReference type="GeneID" id="5003722"/>
    <dbReference type="Gramene" id="ABO97982">
        <property type="protein sequence ID" value="ABO97982"/>
        <property type="gene ID" value="OSTLU_50402"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50402"/>
    <dbReference type="eggNOG" id="KOG2234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024645_5_1_1"/>
    <dbReference type="OMA" id="HLEATTF"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="32668" checksum="3384B6A02070C89C" modified="2007-05-15" version="1">MVSYLFLQVAGTIFASLSRNSDDDYPYDTVVLAFTMESVKLVLSFIFLTTSRACGGVEEVTWSAKRFTSFALPALCYFVANNCMLLIIQELGPSTYQIMNNLKILSTGVLMWTLLGRRLTSLQWRALFLLLLGSVTAEITDSNQLRGSVYGYVLVVINTFIAASGSVLSEKLLKGSNQDGATDSIHWQNMQLYFWGVICGAIPIVWKGEALKNGLFTGFNFYAWVSLVVLSFGGLAVSFILKYLDNIYKCFVSALSMLVVAIIHVCIEHETMPLRIIISIALVSLAMELYTTGAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2J3</accession>
    <name>A4S2J3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_33472</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419541.1">
        <property type="nucleotide sequence ID" value="XM_001419504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2J3"/>
    <dbReference type="STRING" id="436017.A4S2J3"/>
    <dbReference type="GeneID" id="5003658"/>
    <dbReference type="Gramene" id="ABO97834">
        <property type="protein sequence ID" value="ABO97834"/>
        <property type="gene ID" value="OSTLU_33472"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33472"/>
    <dbReference type="eggNOG" id="KOG0548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1573272_0_0_1"/>
    <dbReference type="OMA" id="MDATECI"/>
    <dbReference type="OrthoDB" id="495280at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="117"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="170" mass="18546" checksum="B97E1B6BBD0116DA" modified="2007-05-15" version="1">MAAVHKGEGNRAFQEKRFEDAVASFSRAAALEPKNWVFFSNRSAAYAELGRYDDALDDAKETIRLNCEWTKGYVRLATACSALGRLSEATAAWRRACELDDENASLRESLAKAEAAEESSLKEGKFKFQGSKRKETAGDGEDVAGGDVTEAKKKKKKPPPATLSFADDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2R7</accession>
    <name>A4S2R7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">OSTLU_33543</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasmic vesicle</location>
            <location evidence="14">COPII-coated vesicle membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419581.1">
        <property type="nucleotide sequence ID" value="XM_001419544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2R7"/>
    <dbReference type="STRING" id="436017.A4S2R7"/>
    <dbReference type="GeneID" id="5003576"/>
    <dbReference type="Gramene" id="ABO97874">
        <property type="protein sequence ID" value="ABO97874"/>
        <property type="gene ID" value="OSTLU_33543"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33543"/>
    <dbReference type="eggNOG" id="KOG1986">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008658_3_0_1"/>
    <dbReference type="OMA" id="ISECEFT"/>
    <dbReference type="OrthoDB" id="10256289at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11287">
        <property type="entry name" value="Sec23_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.730:FF:000005">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.380:FF:000001">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000041">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000043">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037550">
        <property type="entry name" value="Sec23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF22">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23 G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0813">Transport</keyword>
    <keyword evidence="7 14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="16">
        <location>
            <begin position="54"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="17">
        <location>
            <begin position="121"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="19">
        <location>
            <begin position="411"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="18">
        <location>
            <begin position="526"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="15">
        <location>
            <begin position="640"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABO97874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="771" mass="84902" checksum="636C3A2D126F0693" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2R8</accession>
    <name>A4S2R8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Plant synaptotagmin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_33544</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptotagmin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419795.1">
        <property type="nucleotide sequence ID" value="XM_001419758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2R8"/>
    <dbReference type="GeneID" id="5003788"/>
    <dbReference type="Gramene" id="ABO98088">
        <property type="protein sequence ID" value="ABO98088"/>
        <property type="gene ID" value="OSTLU_33544"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33544"/>
    <dbReference type="eggNOG" id="KOG1012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_327174_0_0_1"/>
    <dbReference type="OMA" id="HERSVHI"/>
    <dbReference type="OrthoDB" id="498584at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd21677">
        <property type="entry name" value="SMP_SYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045050">
        <property type="entry name" value="Synaptotagmin_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039010">
        <property type="entry name" value="Synaptotagmin_SMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10774:SF190">
        <property type="entry name" value="C2 CALCIUM_LIPID-BINDING ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10774">
        <property type="entry name" value="EXTENDED SYNAPTOTAGMIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17047">
        <property type="entry name" value="SMP_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673151" description="Plant synaptotagmin" evidence="13">
        <location>
            <begin position="21"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="15">
        <location>
            <begin position="84"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="257"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="492"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="654"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="654"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="727"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO98088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="880" mass="95897" checksum="90580D87C8BED6AA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2S7</accession>
    <name>A4S2S7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed DNA polymerase family A palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_34610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419587.1">
        <property type="nucleotide sequence ID" value="XM_001419550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2S7"/>
    <dbReference type="STRING" id="436017.A4S2S7"/>
    <dbReference type="GeneID" id="5003793"/>
    <dbReference type="Gramene" id="ABO97880">
        <property type="protein sequence ID" value="ABO97880"/>
        <property type="gene ID" value="OSTLU_34610"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34610"/>
    <dbReference type="eggNOG" id="KOG0950">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004638_0_0_1"/>
    <dbReference type="OMA" id="QSNAQEW"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08640">
        <property type="entry name" value="DNA_pol_A_plastid_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000051">
        <property type="entry name" value="DNA polymerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="DNA POLYMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133:SF27">
        <property type="entry name" value="DNA POLYMERASE NU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="2">
        <location>
            <begin position="552"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="824" mass="91172" checksum="2E297DCFA47D6D9D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2X5</accession>
    <name>A4S2X5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_34854</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419821.1">
        <property type="nucleotide sequence ID" value="XM_001419784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2X5"/>
    <dbReference type="GeneID" id="5003880"/>
    <dbReference type="Gramene" id="ABO98114">
        <property type="protein sequence ID" value="ABO98114"/>
        <property type="gene ID" value="OSTLU_34854"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34854"/>
    <dbReference type="HOGENOM" id="CLU_2695230_0_0_1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017178">
        <property type="term" value="F:diphthine-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196:SF2">
        <property type="entry name" value="DIPHTHINE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="74" mass="8050" checksum="D4F02528CFB9F4B6" modified="2007-05-15" version="1" fragment="single">MRALVAEKLGEDGATEAWRNVAMTHVYLDDMSQFATVNGVYSRYMPPVAPSARACVATCLPGDAKVQIDCLFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S315</accession>
    <name>A4S315_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_25081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419635.1">
        <property type="nucleotide sequence ID" value="XM_001419598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S315"/>
    <dbReference type="STRING" id="436017.A4S315"/>
    <dbReference type="GeneID" id="5003841"/>
    <dbReference type="Gramene" id="ABO97928">
        <property type="protein sequence ID" value="ABO97928"/>
        <property type="gene ID" value="OSTLU_25081"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25081"/>
    <dbReference type="eggNOG" id="KOG2058">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_351046_0_0_1"/>
    <dbReference type="OMA" id="DHRAEIW"/>
    <dbReference type="OrthoDB" id="17687at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="140"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="658"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="802" mass="88078" checksum="74D781108FE61896" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S375</accession>
    <name>A4S375_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)H dehydrogenase (quinone)</fullName>
            <ecNumber evidence="2">1.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_7955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a quinone + NADPH + H(+) = a quinol + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:46164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419869.1">
        <property type="nucleotide sequence ID" value="XM_001419832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S375"/>
    <dbReference type="STRING" id="436017.A4S375"/>
    <dbReference type="GeneID" id="5003697"/>
    <dbReference type="Gramene" id="ABO98162">
        <property type="protein sequence ID" value="ABO98162"/>
        <property type="gene ID" value="OSTLU_7955"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7955"/>
    <dbReference type="eggNOG" id="KOG3135">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051402_0_2_1"/>
    <dbReference type="OMA" id="MSTTPYI"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="5">
        <location>
            <begin position="2"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="146" mass="15552" checksum="B8B684BA7E890973" modified="2007-05-15" version="1" fragment="single">RVSVVFFSKSARLVTLANVIAEGARAVEGADVRVLRVRDTIRGEDDASAYDRGILDCAVATPEDILESDCIIFGSPTRHGRMAPEMSAFFDRLAAFHSNGCALKGKIGSSFTEVGGAGQGYGGHEICLMTFHSFFLQHGMIAVGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3M7</accession>
    <name>A4S3M7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_88419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419949.1">
        <property type="nucleotide sequence ID" value="XM_001419912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3M7"/>
    <dbReference type="STRING" id="436017.A4S3M7"/>
    <dbReference type="GeneID" id="5004073"/>
    <dbReference type="Gramene" id="ABO98242">
        <property type="protein sequence ID" value="ABO98242"/>
        <property type="gene ID" value="OSTLU_88419"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88419"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_587413_0_0_1"/>
    <dbReference type="OMA" id="HLHHDTM"/>
    <dbReference type="OrthoDB" id="6363363at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052596">
        <property type="entry name" value="AMBRA1_autophagy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874:SF1">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="559"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="567"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="578" mass="63770" checksum="A45ED334798ABC3F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3P9</accession>
    <name>A4S3P9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-binding enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_12975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419957.1">
        <property type="nucleotide sequence ID" value="XM_001419920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3P9"/>
    <dbReference type="STRING" id="436017.A4S3P9"/>
    <dbReference type="GeneID" id="5004087"/>
    <dbReference type="Gramene" id="ABO98250">
        <property type="protein sequence ID" value="ABO98250"/>
        <property type="gene ID" value="OSTLU_12975"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12975"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_17_0_1"/>
    <dbReference type="OMA" id="IPRNAMN"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF8">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="119"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="219" mass="23901" checksum="56E929A021EB0892" modified="2007-05-15" version="1">MALSNPYEESKHKPGYVGLPLPGVQVKLAPLVGADGDEDTSDVDSGEYLQGPGELLVKGDNLFTEYYDNAEATSESFDESGYFKTGDVAAMASDGFWRILGRASVDVLKIGGFKVSALEIEARLLENPSIAEVAVLGIPDEAYGQRAVALVVLALDMETGEPANLTEGDVTLWVRQNLASKMHLRVVKFADKMPRNAMGKVNKKDLQRTHFAEYFEQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3T7</accession>
    <name>A4S3T7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_2597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420151.1">
        <property type="nucleotide sequence ID" value="XM_001420114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3T7"/>
    <dbReference type="STRING" id="436017.A4S3T7"/>
    <dbReference type="GeneID" id="5004160"/>
    <dbReference type="Gramene" id="ABO98444">
        <property type="protein sequence ID" value="ABO98444"/>
        <property type="gene ID" value="OSTLU_2597"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2597"/>
    <dbReference type="eggNOG" id="KOG0596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="QKMRAIP"/>
    <dbReference type="OrthoDB" id="20524at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033316">
        <property type="term" value="P:meiotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14131">
        <property type="entry name" value="PKc_Mps1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000131">
        <property type="entry name" value="Dual specificity protein kinase TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000224">
        <property type="entry name" value="serine/threonine-protein kinase mph1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027084">
        <property type="entry name" value="Mps1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="287" mass="32448" checksum="8BAC5EC602917914" modified="2007-05-15" version="1" fragment="single">VNGVKYTKLECVGQGGTCKVYKVVSPKRKILALKRIRLDGKEHETVAGFIDEIKLLKTLRGRDNIIQLVDAEVCPKEKLIFMVLEFGEIDLAHMLAKREKQRQNHGGVIDDNFLRLYFEQMVEAVNIIHEERIVHSDLKPANFLFVEGALKLIDFGIARAIQTEQAPDHTNIVRDHQVGTVNYMSPEAILNGQASALGGPMKVGRASDIWSLGCILYQMVYGHTPFSKITGMIQKLHAITDPRHTIAFPPLPTENPALIDLMRKCLERDPKNRISVKEILTHRFLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3W5</accession>
    <name>A4S3W5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420164.1">
        <property type="nucleotide sequence ID" value="XM_001420127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3W5"/>
    <dbReference type="GeneID" id="5004031"/>
    <dbReference type="Gramene" id="ABO98457">
        <property type="protein sequence ID" value="ABO98457"/>
        <property type="gene ID" value="OSTLU_17109"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17109"/>
    <dbReference type="HOGENOM" id="CLU_1032042_0_0_1"/>
    <dbReference type="OrthoDB" id="10664013at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="30896" checksum="8ECF448F068F84C3" modified="2007-05-15" version="1">MGSKRWRRSRSATQRRALEEIYEESLEARSLRVVLENVKDSELALAHAEATARNAWAKSLEEASEEKWATRVEETEKENAKLRLDAHKRDVELVAAKAEAKRLRETRAEKPKLVNAVVQTETEVEESAVHKREITAKDAEILALRRELDIAKTQMERETRAHAEEFDALQDELAKTKEASERRRERELAQIKDRAAFFERCSHTADERANGAEATAHALREEFLMIESEVKKLKEQMARNAEHAAEEKESIMSALAAAQARAKTPSCKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S418</accession>
    <name>A4S418_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_8244</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420015.1">
        <property type="nucleotide sequence ID" value="XM_001419978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S418"/>
    <dbReference type="STRING" id="436017.A4S418"/>
    <dbReference type="GeneID" id="5003979"/>
    <dbReference type="Gramene" id="ABO98308">
        <property type="protein sequence ID" value="ABO98308"/>
        <property type="gene ID" value="OSTLU_8244"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8244"/>
    <dbReference type="eggNOG" id="KOG0072">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040729_9_3_1"/>
    <dbReference type="OMA" id="MGAGMSW"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04151">
        <property type="entry name" value="Arl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000510">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 12 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="175" mass="19648" checksum="91BD2B5F54886C68" modified="2007-05-15" version="1" fragment="single">MGVFFSRLFSYFGDREARILVLGLDNAGKTTILYRLQVGTVVSTIPTIGFNVETVTHKNVKFQVWDLGGQTSIRPYWRCYYPNTQAIIYVVDSSDVERVGTSREEFHALLEEEELKDAILLVFANKQDLPGALSDAEVTEQLGLSSIKNRTWSIFKCSALEGKGLFEGLDWLADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S453</accession>
    <name>A4S453_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCR4/nocturin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420209.1">
        <property type="nucleotide sequence ID" value="XM_001420172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S453"/>
    <dbReference type="STRING" id="436017.A4S453"/>
    <dbReference type="GeneID" id="5004184"/>
    <dbReference type="Gramene" id="ABO98502">
        <property type="protein sequence ID" value="ABO98502"/>
        <property type="gene ID" value="OSTLU_26290"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26290"/>
    <dbReference type="eggNOG" id="KOG0620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016428_1_3_1"/>
    <dbReference type="OMA" id="CALFFDR"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF45">
        <property type="entry name" value="NOCTURNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="46"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="349" mass="38524" checksum="8234040DADC82F4D" modified="2007-05-15" version="1">MTTSTSGARTIQVCQYNALADALALNDAFASAYYGEDDAEANEEMYDLNWTKRSKDLLRAITSNDSTTAPDVICMQECDHYYDFFEPELKKLGYAGLYKEDQWSPCRKFGAPCDGVCIFYKTDKLELLSSHAPGTPRARKDDPALNAGKTLMARFRLKKDPRSESGIRNAIGTLIRGNAKPVFSGEDLQEIVVVTTHLESAKTVDGIITRLEQTKELCRHLNAFATSLCADVDKVQIIIAGDLNATPNEACVVHLRGRGMRNAYEDMSAALGDKNSNRFSTWKTRTGLFKTGEVKHTIDYILYSAHRGSKVVSVAKLPDESEIPSDVGLPTFGFPSDHLPLQARIAIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4B7</accession>
    <name>A4S4B7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_3060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420404.1">
        <property type="nucleotide sequence ID" value="XM_001420367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4B7"/>
    <dbReference type="STRING" id="436017.A4S4B7"/>
    <dbReference type="GeneID" id="5004281"/>
    <dbReference type="Gramene" id="ABO98697">
        <property type="protein sequence ID" value="ABO98697"/>
        <property type="gene ID" value="OSTLU_3060"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3060"/>
    <dbReference type="eggNOG" id="KOG1361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005260_2_1_1"/>
    <dbReference type="OMA" id="GCEGYFL"/>
    <dbReference type="OrthoDB" id="262529at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12650:FF:000001">
        <property type="entry name" value="DNA cross-link repair 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="7"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="346" mass="39648" checksum="7D9AFB598E75C64C" modified="2007-05-15" version="1" fragment="single">PAWIRPPGTMFIVDGFEYAASSEARCEHWFLTHFHADHHRGLTRTFDRGVVYGTRTTTELVRTKIGVPRERLRVVEFGVVVRVDGVDVTFLRANHCPGAAMICFEFPHRRDASPVLHTGDFRFHDGMRNDPTLLRITSDPSAPRPILILDTTYCSLEHDDFPTQERVLKAVRDAVVHEDLLSTRKLFLFGTYTIGKEKVFLEAAKVLNRKVYIGKAKRSVMDAIALDPEERSAMTHDDSKTNLHVVPMGSTSFMKMASILKYYKSRFDTVIAFRPTGWTFSAQKKTARATSRRQRGRLIQYGLPYSEHSSLNELREFVRFMNPKFIFPHVNNDGGENAKRMLTLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4E8</accession>
    <name>A4S4E8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420253.1">
        <property type="nucleotide sequence ID" value="XM_001420216.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S4E8"/>
    <dbReference type="GeneID" id="5004455"/>
    <dbReference type="Gramene" id="ABO98546">
        <property type="protein sequence ID" value="ABO98546"/>
        <property type="gene ID" value="OSTLU_26387"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26387"/>
    <dbReference type="HOGENOM" id="CLU_225815_0_0_1"/>
    <dbReference type="OMA" id="DPKCHAG"/>
    <dbReference type="OrthoDB" id="262065at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001368">
        <property type="entry name" value="TNFR/NGFR_Cys_rich_reg"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="28"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="24"/>
    </dbReference>
    <dbReference type="SMART" id="SM00208">
        <property type="entry name" value="TNFR"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="1">
        <location>
            <begin position="310"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="2">
        <location>
            <begin position="311"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="1">
        <location>
            <begin position="386"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="1">
        <location>
            <begin position="500"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="2">
        <location>
            <begin position="501"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="1">
        <location>
            <begin position="576"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="1">
        <location>
            <begin position="690"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="TNFR-Cys" evidence="2">
        <location>
            <begin position="691"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="1">
        <location>
            <begin position="766"/>
            <end position="806"/>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
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                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
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                <person name="Jabbari K."/>
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</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
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    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000180">
        <property type="entry name" value="serine/threonine-protein kinase STY46-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="267" mass="30103" checksum="64D81A2775A8047C" modified="2007-05-15" version="1" fragment="single">FKIAEEELSIGAKLGVGSFGVVHRAKWNDTDVAYKTMIADKMNDDTINAFAEEIRMMRALRHPNIVLFLGAVIQRGRMGIVSELMKRGNLEQLLHGNGKWSESLRSNGMLRRQMAADCARGMLYLHSLAHPVVHHDLKPANLLVDANWTLKVSDFGMSELKSYTYGSNCKAPGGTPEWMAPEALRGDDVNELSDVFSFGVILWELITLNFPWADLSSPVQIVAQVAFLHRRLKIPSWVEDPMEQLLHDCWTRETEARPTFASIVERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4L3</accession>
    <name>A4S4L3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_17301</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420457.1">
        <property type="nucleotide sequence ID" value="XM_001420420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4L3"/>
    <dbReference type="STRING" id="436017.A4S4L3"/>
    <dbReference type="GeneID" id="5004581"/>
    <dbReference type="Gramene" id="ABO98750">
        <property type="protein sequence ID" value="ABO98750"/>
        <property type="gene ID" value="OSTLU_17301"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17301"/>
    <dbReference type="eggNOG" id="KOG2140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006308_3_3_1"/>
    <dbReference type="OMA" id="DRYNDSQ"/>
    <dbReference type="OrthoDB" id="1924287at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000004">
        <property type="entry name" value="pre-mRNA-splicing factor CWC22 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="7">
        <location>
            <begin position="298"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="494"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="504"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="549"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="562" mass="63324" checksum="3B8523E7F851BDEF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Q9</accession>
    <name>A4S4Q9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U2A'/phosphoprotein 32 family A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26496</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ANP32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420311.1">
        <property type="nucleotide sequence ID" value="XM_001420274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Q9"/>
    <dbReference type="STRING" id="436017.A4S4Q9"/>
    <dbReference type="GeneID" id="5004602"/>
    <dbReference type="Gramene" id="ABO98604">
        <property type="protein sequence ID" value="ABO98604"/>
        <property type="gene ID" value="OSTLU_26496"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26496"/>
    <dbReference type="eggNOG" id="KOG2739">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063314_1_0_1"/>
    <dbReference type="OMA" id="VTNENAY"/>
    <dbReference type="OrthoDB" id="2160613at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000131">
        <property type="entry name" value="acidic leucine-rich nuclear phosphoprotein 32-related protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045081">
        <property type="entry name" value="AN32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11375">
        <property type="entry name" value="ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11375:SF0">
        <property type="entry name" value="ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="27115" checksum="93B5819913008BF9" modified="2007-05-15" version="1">MGTTPEKVVTMYLDEKFKSATVEGELLAKCENLKTLSCASCGLTTLAGFPALANLKDLSLNDNRIADGLEALVGCKALSSLSLANNKLANVDDLKAVAEELTLSVLELEANPLTENEDYHEKVMTMMPTLNVLDGRDEFGNEIEDDDEDDDEDEDDEDDEDEDEDDDEDDEDADEDEDEDESEEEEEEEEEEMGLADLYGDKPLEDDDDDDDAFVEDEDPESEDIDEEESDDDEDEAAAKKPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4V6</accession>
    <name>A4S4V6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_44322</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420333.1">
        <property type="nucleotide sequence ID" value="XM_001420296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4V6"/>
    <dbReference type="STRING" id="436017.A4S4V6"/>
    <dbReference type="GeneID" id="5004390"/>
    <dbReference type="Gramene" id="ABO98626">
        <property type="protein sequence ID" value="ABO98626"/>
        <property type="gene ID" value="OSTLU_44322"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44322"/>
    <dbReference type="eggNOG" id="KOG1191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016077_6_2_1"/>
    <dbReference type="OMA" id="CNLPQYV"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042793">
        <property type="term" value="P:plastid transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01894">
        <property type="entry name" value="EngA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01895">
        <property type="entry name" value="EngA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000004">
        <property type="entry name" value="GTPase Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000040">
        <property type="entry name" value="GTPase Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001185">
        <property type="entry name" value="GTPase Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTPase_Der"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43834">
        <property type="entry name" value="GTPASE DER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43834:SF2">
        <property type="entry name" value="GTPASE DER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="9">
        <location>
            <begin position="87"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="9">
        <location>
            <begin position="283"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="555" mass="61305" checksum="FA57CF09E22392E4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S589</accession>
    <name>A4S589_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_47105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420732.1">
        <property type="nucleotide sequence ID" value="XM_001420695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S589"/>
    <dbReference type="GeneID" id="5004795"/>
    <dbReference type="Gramene" id="ABO99025">
        <property type="protein sequence ID" value="ABO99025"/>
        <property type="gene ID" value="OSTLU_47105"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_47105"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_1_0_1"/>
    <dbReference type="OMA" id="ACSISYW"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="482" mass="51260" checksum="B9897B80DED5AB9F" modified="2007-05-15" version="1">MTMNTLRDLVTLVFVGRARATVELAGAALAMTTINIACKSVLVGLASAVNTLAGTAYGLGAYERVGETTQRALLVTTTYAALTCAVFATRGEEFLAATGQDAGVSREAGRFLRAATPGVLCYAWTQCTMTYLHSQGITRPQALGGVLAAIAHPILCYYFVWRWEIGVIGAALAWSASSAVCLATQVAYATVWRRMFRERDEALALKRDMCWPGWQLRRAISTEGLREYFALALPGVAMKMEWWASEMTVVMAGYLPNPEIALSALSIYGSTNAFVFDASIGLGVASLTRVTHELGAGNAKRARRAVAVSFQLIACVGVIASVGIIVARKDWANLFTSREEVRELVSELMIALAAYALFDCAGAVQAGVMRACGKQSLAAKIVVVAYWIIGIPLSLALAFGAHMGALGLVLGGLVATVVHTGALGFVIARRLDWDAEVVSARDRHALSTSHAAEAGYVPRSSSFALLESARANDLTRQYGAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5G9</accession>
    <name>A4S5G9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CP12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420606.1">
        <property type="nucleotide sequence ID" value="XM_001420569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5G9"/>
    <dbReference type="GeneID" id="5004605"/>
    <dbReference type="Gramene" id="ABO98899">
        <property type="protein sequence ID" value="ABO98899"/>
        <property type="gene ID" value="OSTLU_26762"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26762"/>
    <dbReference type="HOGENOM" id="CLU_2965106_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6266" checksum="28EE13D5D74FCC0C" modified="2007-05-15" version="1">MAQAKTDADWAAIEKDVPGARAMHAAAQRTTQAQSTTKTDPMDQLCADDPGAIECKAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5W8</accession>
    <name>A4S5W8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CPA2 family transporter: potassium ion efflux</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_51113</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420682.1">
        <property type="nucleotide sequence ID" value="XM_001420645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5W8"/>
    <dbReference type="GeneID" id="5004883"/>
    <dbReference type="Gramene" id="ABO98975">
        <property type="protein sequence ID" value="ABO98975"/>
        <property type="gene ID" value="OSTLU_51113"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51113"/>
    <dbReference type="eggNOG" id="KOG1650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005126_9_3_1"/>
    <dbReference type="OMA" id="AHFRKLD"/>
    <dbReference type="OrthoDB" id="4834at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004771">
        <property type="entry name" value="K/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00932">
        <property type="entry name" value="2a37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46157:SF2">
        <property type="entry name" value="K(+) EFFLUX ANTIPORTER 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46157">
        <property type="entry name" value="K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="11">
        <location>
            <begin position="403"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="593" mass="61904" checksum="528F98FB4AB0A777" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4S650</accession>
    <name>A4S650_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26992</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420884.1">
        <property type="nucleotide sequence ID" value="XM_001420847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S650"/>
    <dbReference type="GeneID" id="5005090"/>
    <dbReference type="Gramene" id="ABO99177">
        <property type="protein sequence ID" value="ABO99177"/>
        <property type="gene ID" value="OSTLU_26992"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26992"/>
    <dbReference type="eggNOG" id="ENOG502QUCQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080270_0_0_1"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="3">
        <location>
            <begin position="213"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="29254" checksum="087FFCC956687245" modified="2007-05-15" version="1">MALDVASRCVANLRRVDARRRFPRRRAVASSSARDLLDAIAREADDDAIRARVDELTETFELDRAFGGDGDAVAAALHGTWRLAHASKSAFDPRAPLGRRTDATTPGLEAAFATLFDDANASGSGSGSANASGSSSPIQRAVLSKLSDGGFAVRQGVRLRGEARKRRVDQAVCFGDGYGWFRLSANARLDAREGRIDYGFDLAYVDLKKPIAVRVPYPVPFRLLGKEAMGYLTCDYVGDGVRVCTGNKGTTFVFVKEDDDALPYANEFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6F6</accession>
    <name>A4S6F6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_27099</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420935.1">
        <property type="nucleotide sequence ID" value="XM_001420898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6F6"/>
    <dbReference type="STRING" id="436017.A4S6F6"/>
    <dbReference type="GeneID" id="5005043"/>
    <dbReference type="Gramene" id="ABO99228">
        <property type="protein sequence ID" value="ABO99228"/>
        <property type="gene ID" value="OSTLU_27099"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27099"/>
    <dbReference type="eggNOG" id="ENOG502QRMU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1761841_0_0_1"/>
    <dbReference type="OrthoDB" id="1435597at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14703">
        <property type="entry name" value="bZIP_plant_RF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044759">
        <property type="entry name" value="bZIP_RF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13690">
        <property type="entry name" value="TRANSCRIPTION FACTOR POSF21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13690:SF124">
        <property type="entry name" value="TRANSCRIPTION FACTOR RF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="76"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="148" mass="16397" checksum="8B5153C990577D27" modified="2007-05-15" version="1">MTPTPGKHRRSLSTPVDVLASSALQRALDRARDRHGGDDAPSRSDSLFGDEDAMAHAMAIDLDDAPLDVRELAMQDPKRAKRILANRLSAARSKERKTRYVKGLEKKLNELEECERTLILERERMATAVATLAAENSALQMMMGTPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6J7</accession>
    <name>A4S6J7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="2">6.3.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_17852</name>
        <name evidence="9" type="ORF">OSTLU_19257</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420956.1">
        <property type="nucleotide sequence ID" value="XM_001420919.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422938.1">
        <property type="nucleotide sequence ID" value="XM_001422901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6J7"/>
    <dbReference type="STRING" id="436017.A4S6J7"/>
    <dbReference type="GeneID" id="5004961"/>
    <dbReference type="GeneID" id="5006908"/>
    <dbReference type="Gramene" id="ABO99249">
        <property type="protein sequence ID" value="ABO99249"/>
        <property type="gene ID" value="OSTLU_17852"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01297">
        <property type="protein sequence ID" value="ABP01297"/>
        <property type="gene ID" value="OSTLU_19257"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17852"/>
    <dbReference type="KEGG" id="olu:OSTLU_19257"/>
    <dbReference type="eggNOG" id="KOG0237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_719355_0_0_1"/>
    <dbReference type="OMA" id="CMHADGA"/>
    <dbReference type="OrthoDB" id="2018833at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046084">
        <property type="term" value="P:adenine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520:SF12">
        <property type="entry name" value="TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PurM-like N-terminal" evidence="6">
        <location>
            <begin position="38"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="7">
        <location>
            <begin position="171"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="383" mass="41593" checksum="DAF94D931B8FDE57" modified="2007-05-15" version="1">MRGVSASKEDVHAAIKKVDKGLFPKAFCKIVEDIAGDEAYCTCMHADGAGTKTSLAYAYWRETGDLGVWRGIAQDSIVMNTDDLLCVGCVDNIFVSSTIGRNKALIPGEVLSALINGTEEVLETLRECGVGVKSTGGETADLGDLVRTVVVDTTVTARMRRDAVVSNDNIRAGDVVVGLASFGQATYESEYNGGMGSNGLTSARHDVFAKNLAEKYPETFDPNVPESLVYSGKYQLTDVEPETGVTVGKLVLSPTRTYAPVVKAVLDAMDVRDIHGMVHCSGGAQSKVGHFLLDGLRVVKDNMFPIPPLFRLIQECSNTEWSEMYKVFNCGHRLEFYCSPEHAQKIIDISQSFNIDARVVGRVEAKDGKSEVVVKSEYGEFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6M3</accession>
    <name>A4S6M3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_93618</name>
        <name evidence="9" type="ORF">OSTLU_94161</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
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        <property type="gene ID" value="OSTLU_93618"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABP01199"/>
        <property type="gene ID" value="OSTLU_94161"/>
    </dbReference>
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    <dbReference type="KEGG" id="olu:OSTLU_94161"/>
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        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="2"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF213">
        <property type="entry name" value="OS03G0770700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="44"/>
            <end position="105"/>
        </location>
    </feature>
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        <location>
            <begin position="136"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99407.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP01199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="293" mass="32737" checksum="073B37DE5FAC1BCF" modified="2007-05-15" version="1">MPTALRASRARTPTSESAHAVDGLPGTQPRAKKTKEVSGESLGKYRGVYKWKNGKYRAMINSEGKTYGLGVFSDVEAAAMAFDRASIVLGRQPKNFATSNRYEFELDELSKLNGNIQALRRMTSDRAPDKSKSMSVYRGVHRCSRTGRYRSEIEHNGKKFSLGVHAKEEDAARTYDQAAIVCLGGLAVTNFDRQEYQLAHLDHFAGDLDKYRASLHIKIRRQGTSRSRCTSKHEGVRKYEHTWKSGKKTVKWRAEVKVEGKSKQLGYFRSEDEAAQAVKTFRVGYAATATAGA</sequence>
</entry>
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    </gene>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001420943.1"/>
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    <dbReference type="Gramene" id="ABO99273">
        <property type="protein sequence ID" value="ABO99273"/>
        <property type="gene ID" value="OSTLU_13201"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG1036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038526_0_1_1"/>
    <dbReference type="OMA" id="VWGLWNM"/>
    <dbReference type="OrthoDB" id="10262475at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
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        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
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    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="WD40 repeat-like"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
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            <begin position="230"/>
            <end position="255"/>
        </location>
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        <location>
            <begin position="291"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="322" mass="35334" checksum="AA590B04B79FB59B" modified="2007-05-15" version="1">MARRLTLLVTSWDGTARRYACRAREIGDVKSLNSIDLGAPALCGTFVGTDEDAACVGCLDGSVRLVDFKTGAFRVVGAHDDGAVSAVEYDDATKKLFTFGWDRTIRAWDLTKDERGRAVSTTKTAGKCYAADLRDGKIFVATSDGQVLAYETRDLVRAPPRPLINRRSSMRFQTRAIAANIRGDGFVAASVEGRVAVEFIRDEENDKRKYAFKCHRKTDDASVGEIVYPVHAVAFHPVHGTFATGGGDGYVNFWDGDAKKRLFQSPRYPTSISALAFSPCGSLLAIASSYAHEERENNKPEDRVFLRETRAEEVTPKSAKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S788</accession>
    <name>A4S788_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_25487</name>
        <name evidence="7" type="ORF">OSTLU_25519</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421376.1"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S788"/>
    <dbReference type="GeneID" id="5005308"/>
    <dbReference type="GeneID" id="5005346"/>
    <dbReference type="Gramene" id="ABO99706">
        <property type="protein sequence ID" value="ABO99706"/>
        <property type="gene ID" value="OSTLU_25487"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99736">
        <property type="protein sequence ID" value="ABO99736"/>
        <property type="gene ID" value="OSTLU_25519"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25487"/>
    <dbReference type="KEGG" id="olu:OSTLU_25519"/>
    <dbReference type="HOGENOM" id="CLU_928711_0_0_1"/>
    <dbReference type="OrthoDB" id="503186at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043452">
        <property type="entry name" value="BZIP46-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22952">
        <property type="entry name" value="CAMP-RESPONSE ELEMENT BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22952:SF175">
        <property type="entry name" value="PROTEIN ABSCISIC ACID-INSENSITIVE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="244"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="300" mass="31921" checksum="C598DD2B1C266F9D" modified="2007-05-15" version="1">MPRAATRRDATTDDGDDAVMRDDSLRKWARELVPTLSAHADDPALGLTLDALGRGADAATATMREVATAVARQASTIDAKIFDRLPDEAGRQSMGDVWAKINSSGASGTARGREPSLPSLPSLPTMNFMQLTTALALADAGGDEAATTTATVTAGKTAKAKAKRATNGRATAVKKTTTTKTTGSAPSRVSMMIVPTVPGVSYEPKRLKKRSGIATPPAFRQAIAPLKMGRKPKGAPKETEAEKALRMQERLFRNRESAARSREKRESAMRALEEENAALRRELVATKAKLAALQRSGGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7I6</accession>
    <name>A4S7I6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421281.1">
        <property type="nucleotide sequence ID" value="XM_001421244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7I6"/>
    <dbReference type="GeneID" id="5005328"/>
    <dbReference type="Gramene" id="ABO99574">
        <property type="protein sequence ID" value="ABO99574"/>
        <property type="gene ID" value="OSTLU_18114"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18114"/>
    <dbReference type="HOGENOM" id="CLU_415868_0_0_1"/>
    <dbReference type="OrthoDB" id="501705at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="424"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="660" mass="71883" checksum="DC88BD0157711F3B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7J4</accession>
    <name>A4S7J4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_27511</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421462.1">
        <property type="nucleotide sequence ID" value="XM_001421425.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S7J4"/>
    <dbReference type="GeneID" id="5005593"/>
    <dbReference type="Gramene" id="ABO99755">
        <property type="protein sequence ID" value="ABO99755"/>
        <property type="gene ID" value="OSTLU_27511"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27511"/>
    <dbReference type="eggNOG" id="KOG1248">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003753_2_1_1"/>
    <dbReference type="OMA" id="WHCLPAF"/>
    <dbReference type="OrthoDB" id="2192888at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012978">
        <property type="entry name" value="HEAT_RRP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057860">
        <property type="entry name" value="HEAT_RRP12_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052087">
        <property type="entry name" value="RRP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48287">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48287:SF1">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25772">
        <property type="entry name" value="HEAT_RRP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08161">
        <property type="entry name" value="RRP12_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="1023"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1053"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1084"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1123"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1210"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1222"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1240"/>
            <end position="1251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1316" mass="139224" checksum="0E287B16886D8C82" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7W1</accession>
    <name>A4S7W1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Patatin</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_27638</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Lipolytic acyl hydrolase (LAH).</text>
    </comment>
    <comment type="domain">
        <text evidence="3">The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the patatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421520.1">
        <property type="nucleotide sequence ID" value="XM_001421483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7W1"/>
    <dbReference type="GeneID" id="5005429"/>
    <dbReference type="Gramene" id="ABO99813">
        <property type="protein sequence ID" value="ABO99813"/>
        <property type="gene ID" value="OSTLU_27638"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27638"/>
    <dbReference type="eggNOG" id="KOG3773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_850837_0_0_1"/>
    <dbReference type="OMA" id="GFRTWYH"/>
    <dbReference type="OrthoDB" id="197155at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033562">
        <property type="entry name" value="PLPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406:SF7">
        <property type="entry name" value="PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2 3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="122"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="157"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="276"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="39480" checksum="39EFCF4DF0F7BD2F" modified="2007-05-15" version="1">MARATTLARALEGAALTREEWRWMLVVAAALYAANALAHGVFHAKRNPMYLETGKGRLVVAMRVAYGAPAALAQAAWIAAWIAFWEAARKPMWKPRRRHHGDAGARRGRRRTPVVHDGHASVAMCGGGFRTWYHLGVYHGLYERFGAKALEKARWSGSSVGSIMAAIAACGVDPDVVWAHIPEIAALHRDSWMENLTTVGSKCRFLLDDVLPADAHERCTGRCFISVTSLLPLPHNVILTEYDTRDDLIDAVIASTYIPTWTFPGVCLHKGMVCVDGGVCNNLASLSPATLRVGLDPEDKTDWDATIIPSEPKPRYATFIPLDDAELWDMYECGKRDIASWLRSDEGRKFAAKLATDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S802</accession>
    <name>A4S802_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HhH-GPD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_9118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421363.1">
        <property type="nucleotide sequence ID" value="XM_001421326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S802"/>
    <dbReference type="STRING" id="436017.A4S802"/>
    <dbReference type="GeneID" id="5005261"/>
    <dbReference type="Gramene" id="ABO99656">
        <property type="protein sequence ID" value="ABO99656"/>
        <property type="gene ID" value="OSTLU_9118"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9118"/>
    <dbReference type="eggNOG" id="KOG1921">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_3_4_1"/>
    <dbReference type="OMA" id="QIIWYGR"/>
    <dbReference type="OrthoDB" id="2099276at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000703">
        <property type="term" value="F:oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000001">
        <property type="entry name" value="Endonuclease III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286:SF1">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001435">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="7">
        <location>
            <begin position="8"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="186" mass="20086" checksum="5523B75470A040AE" modified="2007-05-15" version="1" fragment="single">QCLVAALMSVQCLDKVALRAFETLRDSTLDREVTLEAIAAMSTRELEQHLSTLNLFRVKAKYIRACADVIRHKFRGEVPRTVGALKTLPGVGDKLAHLVASVSYGGDEDGFAGIVVDTHVKRVAKRLGWAQAGDDVESVRMSVQARVKREEWEAATLGLIALGQRFCHAKAPACAACPVNASCPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S833</accession>
    <name>A4S833_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Erythromycin biosynthesis protein CIII-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421559.1">
        <property type="nucleotide sequence ID" value="XM_001421522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S833"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="GeneID" id="5005827"/>
    <dbReference type="Gramene" id="ABO99852">
        <property type="protein sequence ID" value="ABO99852"/>
        <property type="gene ID" value="OSTLU_93762"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93762"/>
    <dbReference type="HOGENOM" id="CLU_632222_0_0_1"/>
    <dbReference type="OMA" id="RANDECL"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="1">
        <location>
            <begin position="301"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="434" mass="47977" checksum="C52B39F511811FB7" modified="2007-05-15" version="1">MRARRKRFQVIVSACYGSRGDVMPCLTIAAALARRLEGQATVVAMANPVFENAVAANVRFIGVGSRDEYECVQRDHASRRDARVVVRYWLDHLETHAERILEARADAGRTIVLAHTLDLAVRCVDERANDECLTCYSLVLSPALLRTPNQTIPPFAGERLRCFGRSRWAMRAADCLVDIAFAPQLNAFRASLGSTKPVKRVFDEWFLCKAGVFAMYPEYFERAADAGSRKVFQIDFPQEGGDVNVTGLNAIRVAREFIDRDDAPTVVFVSASGNPPFASQFFATAVKAMRRLAGAKAILLTRHRDRIGELPENAIHIDFLPLHLCRDAGLKIAALVHHGTIGCSATALRSAWPQVVVPAAFDQPYNAALLEAMGAAQIIHMTRLTRTRLVKALKIVFKEEARAPETAPRRRANDASSPQARVAEIIAKELLQYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S844</accession>
    <name>A4S844_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phytoene dehydrogenase</fullName>
            <ecNumber evidence="11">1.3.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AOX5</name>
        <name evidence="14" type="ORF">OSTLU_47627</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene with a concomitant isomerization of two neighboring double bonds at the C9 and C9' positions from trans to cis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>2 a plastoquinone + 15-cis-phytoene = 9,9',15-tri-cis-zeta-carotene + 2 a plastoquinol</text>
            <dbReference type="Rhea" id="RHEA:30287"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:48717"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="1.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carotenoid biosynthesis; lycopene biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 11">Plastid</location>
            <location evidence="2 11">Chromoplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.5" evidence="11"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421697.1">
        <property type="nucleotide sequence ID" value="XM_001421660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S844"/>
    <dbReference type="STRING" id="436017.A4S844"/>
    <dbReference type="GeneID" id="5005601"/>
    <dbReference type="Gramene" id="ABO99990">
        <property type="protein sequence ID" value="ABO99990"/>
        <property type="gene ID" value="OSTLU_47627"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_47627"/>
    <dbReference type="eggNOG" id="KOG0029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022687_1_0_1"/>
    <dbReference type="OMA" id="WKEHAMT"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="UniPathway" id="UPA00803"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009509">
        <property type="term" value="C:chromoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016166">
        <property type="term" value="F:phytoene dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000091">
        <property type="entry name" value="15-cis-phytoene desaturase, chloroplastic/chromoplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014102">
        <property type="entry name" value="Phytoene_desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02731">
        <property type="entry name" value="phytoene_desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF45">
        <property type="entry name" value="15-CIS-PHYTOENE DESATURASE, CHLOROPLASTIC_CHROMOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0957">Chromoplast</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="13">
        <location>
            <begin position="80"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601613-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO99990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="552" mass="60885" checksum="F61DA35566728245" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S853</accession>
    <name>A4S853_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zeaxanthin epoxidase (ABA1) (NPQ2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ZEP</name>
        <name evidence="6" type="ORF">OSTLU_1611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421564.1">
        <property type="nucleotide sequence ID" value="XM_001421527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S853"/>
    <dbReference type="STRING" id="436017.A4S853"/>
    <dbReference type="GeneID" id="5005842"/>
    <dbReference type="Gramene" id="ABO99857">
        <property type="protein sequence ID" value="ABO99857"/>
        <property type="gene ID" value="OSTLU_1611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1611"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_16_0_1"/>
    <dbReference type="OMA" id="WKLCHLP"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006970">
        <property type="term" value="P:response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010114">
        <property type="term" value="P:response to red light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009414">
        <property type="term" value="P:response to water deprivation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016123">
        <property type="term" value="P:xanthophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46496">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46496:SF1">
        <property type="entry name" value="ZEAXANTHIN EPOXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="3"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="47195" checksum="507E5CEED842F3C8" modified="2007-05-15" version="1" fragment="single">KPKVLVAGGGIAGLVAAAACRRKGMEVRVFEKVKKYEPFGGPIQLQCNAQGALDSIDPAMAEAVTAKGTITGDRVNGLLDGVSGEWFYRFDTRKPCHDNGLPLTLVLSRFELLDILSNGVGAENIEMGTVVERYEHRGEKVVATLTDGREFEGDVLIGADGIRSKLRAQMRGADPEKPPLAYAGYAVYTAVCKYSQPHREPQHTDPNKVGYQVFLGPKQYFVSSDVGNGEQQYYAFLEVPPGGDDEFAKCEKWENYREMLMDRFSGWAPAVMERLECTRPEDVERRDVNDILPDPRWVDGRMALLGDSAHAVQPNLGQGGGQAIESAYVLADELSKCEGGKGVQNALMAYASRRFLRTASIHGLSRFSSLMNTFYRRHLGDEPYDWYPEPVKNMWNTVAKAKIPHPGSVIGQIALIGTMPIILEYVGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8A7</accession>
    <name>A4S8A7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421733.1">
        <property type="nucleotide sequence ID" value="XM_001421696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8A7"/>
    <dbReference type="GeneID" id="5005628"/>
    <dbReference type="Gramene" id="ABP00027">
        <property type="protein sequence ID" value="ABP00027"/>
        <property type="gene ID" value="OSTLU_18320"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18320"/>
    <dbReference type="HOGENOM" id="CLU_432544_0_0_1"/>
    <dbReference type="OrthoDB" id="10543538at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="633" mass="69515" checksum="3E1BF15118CFD90B" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8F8</accession>
    <name>A4S8F8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421611.1">
        <property type="nucleotide sequence ID" value="XM_001421574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8F8"/>
    <dbReference type="STRING" id="436017.A4S8F8"/>
    <dbReference type="GeneID" id="5005700"/>
    <dbReference type="Gramene" id="ABO99904">
        <property type="protein sequence ID" value="ABO99904"/>
        <property type="gene ID" value="OSTLU_18359"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18359"/>
    <dbReference type="eggNOG" id="ENOG502QU5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042215_1_0_1"/>
    <dbReference type="OMA" id="PYWWALP"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF2">
        <property type="entry name" value="LYSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="439" mass="48319" checksum="092591F23006A82B" modified="2007-05-15" version="1">MATTTTTADAARAAAGAARRLQETYFAATSKAIAPERWYPYWWALPLAPYGSKATALAEAVPGEVWTFDQLQGLLDVLVNVRMTVARLEGGGLWVHNPVAPTKELVGMVKELEKRYGAVKHIVVGSAAIEHKIYSGPFSKAFPNADVWLPPKNWTFPVDVPLETYVPFYPQGSPKTLPMQSIGGEQNVPWANEIEHAVLQVGGSSLRGFKDPWFVDTAFYLKRTKTVVLTDVMEKVSQQAPPVCQINPQPLLVRAMDEPDKVPANTSQARSDGWGKTVLFGLLFNPNAVEFEFSGDIANDLLDGFKWDPSWRADFDALVAKPMFVPPILAVLAFPRRRDEVKRWSNIVTSWDFTSIIPSHLDGPFNATPDEFTAAMDFALTATPYEQFGANAQSLIDVDKLSVDLKSLEVPKPLSPELITPPKPAQEAVEIVLDAASEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8K1</accession>
    <name>A4S8K1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_40743</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421637.1">
        <property type="nucleotide sequence ID" value="XM_001421600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8K1"/>
    <dbReference type="STRING" id="436017.A4S8K1"/>
    <dbReference type="GeneID" id="5005746"/>
    <dbReference type="Gramene" id="ABO99930">
        <property type="protein sequence ID" value="ABO99930"/>
        <property type="gene ID" value="OSTLU_40743"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40743"/>
    <dbReference type="eggNOG" id="KOG0938">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026996_5_2_1"/>
    <dbReference type="OMA" id="VWKIPRI"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0168">Coated pit</keyword>
    <keyword evidence="2" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="206"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="478" mass="53432" checksum="3CED65E225202ADB" modified="2007-05-15" version="1">MSSAPAPPVRVGHALSGIFVINLRGDVLLMRAYREDIERHVLDAFRTQILNPRDDGFATEAPVRRIGSVTYMMKRSRDVYVVGIARGQGERGGPGDANLMLGFTFLGHVVRLCNQYFGACDENAIRGNFVLMYELLDEICDDGYPQITAGETLKTYITQKGSKLEGAIGKEAMERSAAEDQRRAMEAAKQVTSAVQWRREGLSYKKNEVYLDIVESVNLMMSAEGTVLRANVQGSIYMRTFLSGMPNLSVGLNDRLGETTRVTSRGEDAETSAARDRRLIDLDDLQFHQCVRLDKFSAEKVIEFTPPDGEFELVKYRVSDNITLPFKLMPVVKELGRTRLAVTVNLRSLYGPTTVANEIKVRIPVPKLTARATINVSGGKAKYVPEEGCLRWKIKKCAGHEEYQLDAEVLLANTLEDHKPWVQPPINIAFHVPMFTASGLRVRFLEVKEASNYDVVRWVRYLCQSGGSSSSSYEIRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8T8</accession>
    <name>A4S8T8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HopJ type III effector protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421949.1">
        <property type="nucleotide sequence ID" value="XM_001421912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8T8"/>
    <dbReference type="GeneID" id="5005991"/>
    <dbReference type="Gramene" id="ABP00243">
        <property type="protein sequence ID" value="ABP00243"/>
        <property type="gene ID" value="OSTLU_27965"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27965"/>
    <dbReference type="eggNOG" id="ENOG502S8T7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121622_0_0_1"/>
    <dbReference type="OMA" id="CKIFAFA"/>
    <dbReference type="OrthoDB" id="10267503at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.160.10">
        <property type="entry name" value="vpa0580 domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014984">
        <property type="entry name" value="HopJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038604">
        <property type="entry name" value="HopJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08888">
        <property type="entry name" value="HopJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="15522" checksum="A99CAE6BFAEB7200" modified="2007-05-15" version="1">MRAQALATNANPSVKAIVDTLAELAEQEFGLANVKFQEVMAKMDECFDFEPTAYASGVGTSRETRNAAGTNSGSCKTFYFAKMRGLSEGAALRLFCEHYEDVANAPSGDSHANIRAFMENGYDGLTFEGEALRAKGAGSAMNNDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Z9</accession>
    <name>A4S8Z9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAM21/CAPZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421979.1">
        <property type="nucleotide sequence ID" value="XM_001421942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Z9"/>
    <dbReference type="GeneID" id="5005875"/>
    <dbReference type="Gramene" id="ABP00273">
        <property type="protein sequence ID" value="ABP00273"/>
        <property type="gene ID" value="OSTLU_25653"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25653"/>
    <dbReference type="HOGENOM" id="CLU_683986_0_0_1"/>
    <dbReference type="OMA" id="PARWGTY"/>
    <dbReference type="OrthoDB" id="10613968at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="47302" checksum="7F8028541C84557F" modified="2007-05-15" version="1">MSRGDDDALDALDALDALDATREPWRLGHDRALIERARASDARALERCARTATAVDGNALETSYATCEIASVSCGFRILSNSQFLEKRVDERDDDDDEVDGVGKESARSASETKENEDGETPEAYAEAARRAMEAIRGRWAETRDGGLALTGNEHWRPLPAVIGTTAYYHDESCGLDPKVAKNPNPARWGTYISSDDEDSSEVSEDSSDEFESDISSEFVSSTSSEGEYSDMEDNLADVENNFGDVDGSYALAGAGGDGLFSSVGLSSATTAAKKAAPSYALSFDDVFGDDVRKSKGGLFDDVEGDDGGLFGGASGKAPLASAPAPLASAPAKPPAAAPKKPKGLFDSDSDDDDGDLFGITRRPSGGDLFSEPITDPLDALKSVESKKTDAKTLVPPSSAVASMSIAVPEPKKSPTALFDSDSDSDDGGLFSTKPKEVKKAPPREGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9N0</accession>
    <name>A4S9N0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_18661</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422199.1">
        <property type="nucleotide sequence ID" value="XM_001422162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9N0"/>
    <dbReference type="GeneID" id="5006154"/>
    <dbReference type="Gramene" id="ABP00516">
        <property type="protein sequence ID" value="ABP00516"/>
        <property type="gene ID" value="OSTLU_18661"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18661"/>
    <dbReference type="HOGENOM" id="CLU_685852_0_0_1"/>
    <dbReference type="OrthoDB" id="498419at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017095">
        <property type="term" value="F:heparan sulfate 6-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010635">
        <property type="entry name" value="Heparan_SO4-6-sulfoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12812">
        <property type="entry name" value="HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12812:SF0">
        <property type="entry name" value="HEPARAN-SULFATE 6-O-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="45432" checksum="44B4E429781A4222" modified="2007-05-15" version="1">MGVERGDAEPLLRASRDVERASDDAETTAAKLAVDRTRGAASARLVVGACAVAACLVGASARADWAHRRGGALAEREEVEAFGRELNVGDLSKYYEIPRKAKSVKQTHANRVLFYNFLHVPKTGGTFFHSVLRQVERRVNRKPKQEAFLGEELFPHDHESIAQWITWPLVDTTRENYAATRRHFATGEPAEYFGVDRLRKMYESGARIFSKGSYGMGLCEVVDAPCAYITILRDPVERFLSHYKYSCLAGAENRRLWNKAMKDKGECAMNLVEWHDYLGGDNWLHVLAPGGGENKDAQVAAAIANLDDPCFKFLLTEKLDDGLEKLTTLPDFARLNATLLANFAQHNEAPELDAHQQRLYDRHVANEDMMAHLRRNLRKSLAVYAHAKRTYERKWRQRLLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Z4</accession>
    <name>A4S9Z4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">heme oxygenase (biliverdin-producing)</fullName>
            <ecNumber evidence="3">1.14.14.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_89558</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heme oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.18" evidence="3"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422256.1">
        <property type="nucleotide sequence ID" value="XM_001422219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9Z4"/>
    <dbReference type="STRING" id="436017.A4S9Z4"/>
    <dbReference type="GeneID" id="5006211"/>
    <dbReference type="Gramene" id="ABP00573">
        <property type="protein sequence ID" value="ABP00573"/>
        <property type="gene ID" value="OSTLU_89558"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89558"/>
    <dbReference type="eggNOG" id="KOG4480">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063325_1_2_1"/>
    <dbReference type="OMA" id="PPEFICH"/>
    <dbReference type="OrthoDB" id="652091at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016951">
        <property type="entry name" value="Haem_Oase_decyc_pln"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35703">
        <property type="entry name" value="HEME OXYGENASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35703:SF2">
        <property type="entry name" value="HEME OXYGENASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="221" mass="25084" checksum="62B674D3FCA486F3" modified="2007-05-15" version="1">MGQQKGFVEEMRRVAMSLHTREQAPREGEKKTDATKSEQKPVARWTPTAEGYLNFLVESLAVYEAMERVVAANENEKTYGKFNNCGLERSEALRKDIKYMEERFGLAPREATGAGKEYAETLKALAATSPPEFICHFYNVYFAHSAGGRMIGRKVSELILDGKELEFYEWRANGGLDESLARVRNLLNETAEAWSREEKDRCLEETGKSFQLSGQLLRLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAB8</accession>
    <name>A4SAB8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_8561</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422409.1">
        <property type="nucleotide sequence ID" value="XM_001422372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAB8"/>
    <dbReference type="STRING" id="436017.A4SAB8"/>
    <dbReference type="GeneID" id="5006416"/>
    <dbReference type="Gramene" id="ABP00726">
        <property type="protein sequence ID" value="ABP00726"/>
        <property type="gene ID" value="OSTLU_8561"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8561"/>
    <dbReference type="eggNOG" id="KOG0627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030308_8_4_1"/>
    <dbReference type="OMA" id="TIAWNEN"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000037">
        <property type="entry name" value="Heat stress transcription factor B-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="11">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="166" mass="18990" checksum="FF776B1F1B77F83C" modified="2007-05-15" version="1" fragment="single">KTWNLVSDEHSNDTIAWNENGRTFTVWKPDVLESEYLPKTFKHSNFASFVRQLNNYGFRKCHSDRYEFGVEGFERGKPELLTTLKRHDAPRTKKTGAGATGKKTGGGASARGLASEVEQLKRDRLLLLKEVMRLRETQSSQRDEVAALTNRLAVTESFQTQMRHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAC4</accession>
    <name>A4SAC4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422362.1">
        <property type="nucleotide sequence ID" value="XM_001422325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAC4"/>
    <dbReference type="GeneID" id="5006468"/>
    <dbReference type="Gramene" id="ABP00679">
        <property type="protein sequence ID" value="ABP00679"/>
        <property type="gene ID" value="OSTLU_28521"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28521"/>
    <dbReference type="eggNOG" id="KOG2793">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055721_5_1_1"/>
    <dbReference type="OMA" id="LRSWAWK"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF154">
        <property type="entry name" value="PROTEIN N-LYSINE METHYLTRANSFERASE METTL21A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="229" mass="25827" checksum="9C0CA7B113326A64" modified="2007-05-15" version="1">MKTDEERFRDDYVYDRDDDEDDANPKATIRLRQRKFNAASSGFASTVWDSAIVLAKYLEKRNRASGAGARWRDAVELGAGCGLCACVLAKRCENLVTGTIYATDVAENMDLLTENVKACSSRIAPLAYDWRDAPPKSIDASRVDLILGTDLVYYDDAMPALVKTLKSFESEALVVYFAFGRNRQALPRFLECFDAEARDAFEEPRFLESHELDALYQCTDVSVMELKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAX5</accession>
    <name>A4SAX5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_6328</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422514.1">
        <property type="nucleotide sequence ID" value="XM_001422477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAX5"/>
    <dbReference type="STRING" id="436017.A4SAX5"/>
    <dbReference type="GeneID" id="5006572"/>
    <dbReference type="Gramene" id="ABP00831">
        <property type="protein sequence ID" value="ABP00831"/>
        <property type="gene ID" value="OSTLU_6328"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6328"/>
    <dbReference type="eggNOG" id="KOG4491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036918_3_1_1"/>
    <dbReference type="OMA" id="MSSFACC"/>
    <dbReference type="OrthoDB" id="30881at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF14">
        <property type="entry name" value="PROTEIN PGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="27531" checksum="3601043EAD09CA75" modified="2007-05-15" version="1" fragment="single">PHARAIGSMALGLLLALVGYKKKSLDESGALAAIGVGFGSIYADVRFGAALAAFFFASSAVTRVRSDVKKRVDEHFKVGGGRDWVQVFANGFVPTVIALAFASGGFGAEATSALASAYLGYYACCGGDTFASELGVLSKSKPRLIIDWRREVAAGTNGGVTALGWVASASGGAVVGAAFHLGQSALRAVATDGGALVAPSNAASVIAFGAVAGVFGSLVDSVLGATIQYSGFCEERQKVVSKPGPTVTRISGSEFLSNSAVNLVSGVITAVVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB14</accession>
    <name>A4SB14_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_19023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422697.1">
        <property type="nucleotide sequence ID" value="XM_001422660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB14"/>
    <dbReference type="GeneID" id="5006754"/>
    <dbReference type="Gramene" id="ABP01014">
        <property type="protein sequence ID" value="ABP01014"/>
        <property type="gene ID" value="OSTLU_19023"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19023"/>
    <dbReference type="HOGENOM" id="CLU_977919_0_0_1"/>
    <dbReference type="OrthoDB" id="10492449at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP01014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="285" mass="31428" checksum="5F6106E0B804C137" modified="2007-05-15" version="1">MSRYGVDEAIGGLLDDALIGVDRRARAVEAASVAPTPRYGGSLSEDDDDVPLAARVGGGKRAREREETNGVGRGRTAWGSFVAGQLPGRAVSETFDVDEEGRRVSTEAPAGWDELCRKEFDGKKSARRAVMDWYCSTSACSARLIVDKWQESKVRYVLRCCRSLPKRQDKNNAKLVQQIQKRCSMAVCLRYNRDQNCWLVAESESSPRHSALCEDHVRPNVSSALFAQHLDGIEKVPIEFRAEFVARRLKESGLKVTSGTKQRAVSLALERAERASADAPRASLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBE1</accession>
    <name>A4SBE1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422600.1">
        <property type="nucleotide sequence ID" value="XM_001422563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBE1"/>
    <dbReference type="STRING" id="436017.A4SBE1"/>
    <dbReference type="GeneID" id="5006818"/>
    <dbReference type="Gramene" id="ABP00917">
        <property type="protein sequence ID" value="ABP00917"/>
        <property type="gene ID" value="OSTLU_29575"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29575"/>
    <dbReference type="HOGENOM" id="CLU_2999859_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="57" mass="6359" checksum="67B256ECAF7C2F2F" modified="2007-05-15" version="1">MLDKMKDLGNSLLGNFGLSLDNFKAEKDATTGSYSIHFVDEKKRSTTGDEDDEDDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQD1</accession>
    <name>A4RQD1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_6791</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818:SF0">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672820" description="TsaA-like domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="TsaA-like" evidence="4">
        <location>
            <begin position="78"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO93770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="36576" checksum="EC00F7BAB04CB77A" modified="2007-05-15" version="1">MAHVALALVALVALARATTRDEGEALRRAEDARAAERRGRTTAERALREARLELERCRRAMDARGGATRARASTSHEMMAMGTFASAFDRRLGTPRQPSLVPLARGRVELDARVPASALEGLDEFTHCWLVYVFHENTDLGAGAEKNGKVGAADGPKSTLRGKIRVPRLNGEKRGCLATRTPHRPCPIGLSLVRIVRVNGKSLDVAGADLVHGTPVLDVKPYVPYSDCVVDARAPEWVGNDLADGDGPLTVDEVKLTDAGEAALRAAWERRRKDSLYESADEFVAFVTQALGRDIRSYHQRLGDVAPDTDWRVSLDGVIVVYRQSAKRVVVVGAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRF7</accession>
    <name>A4RRF7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Threonylcarbamoyl-AMP synthase</fullName>
            <ecNumber evidence="5">2.7.7.87</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_6322</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Interacts with RSC1A1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SUA5 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="5"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415562.1">
        <property type="nucleotide sequence ID" value="XM_001415525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRF7"/>
    <dbReference type="STRING" id="436017.A4RRF7"/>
    <dbReference type="GeneID" id="4999550"/>
    <dbReference type="Gramene" id="ABO93854">
        <property type="protein sequence ID" value="ABO93854"/>
        <property type="gene ID" value="OSTLU_6322"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6322"/>
    <dbReference type="eggNOG" id="KOG3051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031397_5_1_1"/>
    <dbReference type="OMA" id="PATEHYA"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000007">
        <property type="entry name" value="YrdC N6-threonylcarbamoyltransferase domain containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF10">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="YrdC-like" evidence="16">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO93854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="195" mass="20456" checksum="ECE92A8C84C30B3B" modified="2007-05-15" version="1" fragment="single">AAAALRRGGVIAVPTDTIYGFAASAANGDAVRRLYEIKGRRAGVPLAIAVGDVRDVGTYGDDGHLREGALARLLPGPTTVLLRRRRGDAGRATPELNPGVDLIGIRVPAHDFVREVCRAHGGAIALTSANRSGETSATAAEEFAELWDACDEVFDGGAIPAKRLGSTIVDLSSRANDFAIVRAGERCDELVRVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRL6</accession>
    <name>A4RRL6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Inositol-pentakisphosphate 2-kinase</fullName>
            <ecNumber evidence="1 6">2.7.1.158</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_13884</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20313"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.158"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.158" evidence="1 6"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415590.1">
        <property type="nucleotide sequence ID" value="XM_001415553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRL6"/>
    <dbReference type="STRING" id="436017.A4RRL6"/>
    <dbReference type="GeneID" id="4999445"/>
    <dbReference type="Gramene" id="ABO93882">
        <property type="protein sequence ID" value="ABO93882"/>
        <property type="gene ID" value="OSTLU_13884"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13884"/>
    <dbReference type="eggNOG" id="KOG4749">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_557071_0_0_1"/>
    <dbReference type="OMA" id="GQMAKDC"/>
    <dbReference type="OrthoDB" id="272370at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035299">
        <property type="term" value="F:inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.110">
        <property type="entry name" value="Inositol-pentakisphosphate 2-kinase, N-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009286">
        <property type="entry name" value="Ins_P5_2-kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043001">
        <property type="entry name" value="IP5_2-K_N_lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456:SF2">
        <property type="entry name" value="INOSITOL-PENTAKISPHOSPHATE 2-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06090">
        <property type="entry name" value="Ins_P5_2-kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="433" mass="47418" checksum="9EF349E12226F7DB" modified="2007-05-15" version="1">MRDARASASTSAAVIRITADDVAHYAYAREGNAHVVFRYTGPRPELRGALLRLLKTPAGARGDRAWRCHTVDALVWGADRDEASWTTLDAAARDAFFANAPTTSGRAGWRDDRAVVRVDGDALNALALKTTRDAAHETARAEGRDGRVANAAEAFGQLSEVAAETSRVFEDDVENAWVIEIKPKSFVGAIVNGRRAWRFPAHQRLKVARGEREAASSYVPVDLLGGDADVRRACEALMACPQNNLRVTRGARVFVDARGVTADADVVSTLSRVLPNLVMNAREVFEFIFHHQLRGGDDAVKTYRDVHELCERLNATRQRAGEVSEDLLERLRSFVLGQMAKDCSVLFTVTFDVNVSDIESRDDDLVRFATFVDADGATRACAYRAQIIDASLKSLAKTSAWLRLAEDIDASCVADADADDSRRDFVNALFAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRP5</accession>
    <name>A4RRP5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NADPH--hemoprotein reductase</fullName>
            <ecNumber evidence="8">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_44507</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="8"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415936.1">
        <property type="nucleotide sequence ID" value="XM_001415899.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRP5"/>
    <dbReference type="STRING" id="436017.A4RRP5"/>
    <dbReference type="GeneID" id="4999510"/>
    <dbReference type="Gramene" id="ABO94228">
        <property type="protein sequence ID" value="ABO94228"/>
        <property type="gene ID" value="OSTLU_44507"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44507"/>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_17_3_1"/>
    <dbReference type="OMA" id="MTPTRIH"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000001">
        <property type="entry name" value="NADPH--cytochrome P450 reductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="10">
        <location>
            <begin position="167"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="563" mass="61522" checksum="9A71F5FB1A626C75" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRY7</accession>
    <name>A4RRY7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_86278</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415986.1">
        <property type="nucleotide sequence ID" value="XM_001415949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRY7"/>
    <dbReference type="GeneID" id="4999991"/>
    <dbReference type="Gramene" id="ABO94278">
        <property type="protein sequence ID" value="ABO94278"/>
        <property type="gene ID" value="OSTLU_86278"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86278"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_4_2_1"/>
    <dbReference type="OMA" id="LYWSALM"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF53">
        <property type="entry name" value="PROTEIN ACTIVITY OF BC1 COMPLEX KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="190"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="620" mass="68810" checksum="A3075EF2DF3FDA4C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSL2</accession>
    <name>A4RSL2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_36251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416225.1">
        <property type="nucleotide sequence ID" value="XM_001416188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSL2"/>
    <dbReference type="STRING" id="436017.A4RSL2"/>
    <dbReference type="GeneID" id="5000360"/>
    <dbReference type="Gramene" id="ABO94518">
        <property type="protein sequence ID" value="ABO94518"/>
        <property type="gene ID" value="OSTLU_36251"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36251"/>
    <dbReference type="eggNOG" id="ENOG502QR65">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038110_0_0_1"/>
    <dbReference type="OMA" id="WTGIVST"/>
    <dbReference type="OrthoDB" id="191568at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090415">
        <property type="term" value="F:7-hydroxymethyl chlorophyll a reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033354">
        <property type="term" value="P:chlorophyll cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007516">
        <property type="entry name" value="Co_F420_Hydgase/DH_bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045220">
        <property type="entry name" value="FRHB/FDHB/HCAR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007525">
        <property type="entry name" value="FrhB_FdhB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31332">
        <property type="entry name" value="7-HYDROXYMETHYL CHLOROPHYLL A REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31332:SF0">
        <property type="entry name" value="7-HYDROXYMETHYL CHLOROPHYLL A REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04432">
        <property type="entry name" value="FrhB_FdhB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04422">
        <property type="entry name" value="FrhB_FdhB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal" evidence="1">
        <location>
            <begin position="98"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal" evidence="2">
        <location>
            <begin position="181"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="46650" checksum="ADADA7125702DA1A" modified="2007-05-15" version="1">MTRVGVPLVAAAPPRASRVAARATSARPIAPGSAYPAKEHCSECGLCDTAHVARVKEACAFLGPGQSRIETLEPVVHGRARSAAPSDESRLGVALETFYGAMRTPVDGAQWTGIVTSVALAALRSGAVEGVVCVASREDDSRAPRPILATTEEEILSARGVKPSLSPNLSVLAEVEARGLKRVLFIGVGCAVSALRAVEPHLGLDALYVVGTNCTDNGRWEGFNKFIDAASDDPDTVMHYEFMQDYQVPYFCLPAKDLTDVIAPSCYSCFDYVNGLADVVVGYMGVPYMDKPMDRHPQYVTVRNERGREMIDLIRNDMEITPSTSSGDRRPFVMQTVVADDEAKLGRGPDKPAPRVVGKLLAWLLTKIGPKGKEFGMYSLDYHTIRNYMYVNRAWGAKRAEEHVPEYAKRVVREYDVDGAISARLRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSN9</accession>
    <name>A4RSN9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase II subunit beta</fullName>
            <shortName evidence="2">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_44941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays a complex role in regulating the basal catalytic activity of the alpha subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416461.1">
        <property type="nucleotide sequence ID" value="XM_001416424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSN9"/>
    <dbReference type="STRING" id="436017.A4RSN9"/>
    <dbReference type="GeneID" id="5000118"/>
    <dbReference type="Gramene" id="ABO94754">
        <property type="protein sequence ID" value="ABO94754"/>
        <property type="gene ID" value="OSTLU_44941"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44941"/>
    <dbReference type="eggNOG" id="KOG3092">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034027_3_1_1"/>
    <dbReference type="OMA" id="DADFGRC"/>
    <dbReference type="OrthoDB" id="3971593at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000005">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000001">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="215" mass="24762" checksum="AD3A56CADB5900B6" modified="2007-05-15" version="1">MKKPAYLSDETASSGDDSFDDSIEDTEQSWIAWFCGLKGNELFCEVDEEYIQDDFNLSGLSSSVPYYDYALDTILDVERGHSTLSEQQQELVESAAEMLYGLIHARYILTQRGMTLMLEKYKQNHFGRCPRFMCANTPCLPVGTSDIFRTATVKIFCPKCKDIYFPRSKYQGNTDGAYFGTTFPHLFLMSFKHLQTPKQTDLYEPRIFGFKIRDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RST8</accession>
    <name>A4RST8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="6">2.2.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DXS</name>
        <name evidence="14" type="ORF">OSTLU_48774</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="6"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416190.1">
        <property type="nucleotide sequence ID" value="XM_001416153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RST8"/>
    <dbReference type="STRING" id="436017.A4RST8"/>
    <dbReference type="GeneID" id="5000134"/>
    <dbReference type="Gramene" id="ABO94483">
        <property type="protein sequence ID" value="ABO94483"/>
        <property type="gene ID" value="OSTLU_48774"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48774"/>
    <dbReference type="eggNOG" id="KOG0523">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009227_1_4_1"/>
    <dbReference type="OMA" id="QVGYHAQ"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000002">
        <property type="entry name" value="1-deoxy-D-xylulose-5-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000005">
        <property type="entry name" value="1-deoxy-D-xylulose-5-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003933">
        <property type="entry name" value="PRK05444.2-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="1-D-DEOXYXYLULOSE 5-PHOSPHATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322:SF5">
        <property type="entry name" value="1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="13">
        <location>
            <begin position="415"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="746" mass="80349" checksum="2C23DF42319B643F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTF7</accession>
    <name>A4RTF7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">diaminopimelate epimerase</fullName>
            <ecNumber evidence="3">5.1.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_35896</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S,6S)-2,6-diaminopimelate = meso-2,6-diaminopimelate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416323.1">
        <property type="nucleotide sequence ID" value="XM_001416286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTF7"/>
    <dbReference type="STRING" id="436017.A4RTF7"/>
    <dbReference type="GeneID" id="5000523"/>
    <dbReference type="Gramene" id="ABO94616">
        <property type="protein sequence ID" value="ABO94616"/>
        <property type="gene ID" value="OSTLU_35896"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35896"/>
    <dbReference type="eggNOG" id="ENOG502QQKJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053306_2_1_1"/>
    <dbReference type="OMA" id="EIRIWER"/>
    <dbReference type="OrthoDB" id="4768at2759"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.10:FF:000009">
        <property type="entry name" value="Diaminopimelate epimerase chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689:SF0">
        <property type="entry name" value="DIAMINOPIMELATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="DIAMINOPIMELATE EPIMERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="59"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="407" mass="44642" checksum="8D84BED32AC577B9" modified="2007-05-15" version="1">MCTEPPRDERRRDPPSRRAPPHFAPRARPTTAHHARARRHRFARLEVRARVRLARPVAAARARSVARRPYPLATRRRARSTADSPRARFSPRRSTPRASHARATRVGRARVVAEASRTIDFIKYQGLGNDFILIDNRDSATVKMSSEAAAKMCDRNFGIGGDGVIFAMPPNDASEDYSMRMFNSDGSEPEMCGNGIRCLARFVSDLDAMPPKKYKVGTLAGLIQPEMRADGQVAVDMGMPIFEPSEVPTTLAATQDGKVVRAEMDVDGEKWLVNAVSMGNPHCITFGRAGGEADGPGLKLDEFPLSVVGPKFESHPCFPARTNTEFTQVVNRNYVKMHVWERGAGATLACGTGACATVVAGVLEGRVDRRCTVELPGGPLEIEWRESDGRIIMTGPAEPVFAGKYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTQ4</accession>
    <name>A4RTQ4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_14418</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416533.1">
        <property type="nucleotide sequence ID" value="XM_001416496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTQ4"/>
    <dbReference type="STRING" id="436017.A4RTQ4"/>
    <dbReference type="GeneID" id="5000860"/>
    <dbReference type="Gramene" id="ABO94826">
        <property type="protein sequence ID" value="ABO94826"/>
        <property type="gene ID" value="OSTLU_14418"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14418"/>
    <dbReference type="eggNOG" id="KOG0213">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002242_0_1_1"/>
    <dbReference type="OMA" id="EERLMCH"/>
    <dbReference type="OrthoDB" id="438939at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000039">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000069">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000541">
        <property type="entry name" value="Splicing factor 3B subunit 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08920">
        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="9">
        <location>
            <begin position="94"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="10">
        <location>
            <begin position="873"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1091" mass="122288" checksum="D198328D504C989A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTT4</accession>
    <name>A4RTT4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NAD(+) kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_34253</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416552.1">
        <property type="nucleotide sequence ID" value="XM_001416515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTT4"/>
    <dbReference type="STRING" id="436017.A4RTT4"/>
    <dbReference type="GeneID" id="5000595"/>
    <dbReference type="Gramene" id="ABO94845">
        <property type="protein sequence ID" value="ABO94845"/>
        <property type="gene ID" value="OSTLU_34253"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34253"/>
    <dbReference type="eggNOG" id="KOG4180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067437_0_0_1"/>
    <dbReference type="OMA" id="KSVEWKA"/>
    <dbReference type="OrthoDB" id="185618at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13158">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13158:SF5">
        <property type="entry name" value="NAD KINASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36904" checksum="68113CB7D716B4C4" modified="2007-05-15" version="1">MTEYTSLIGSGELYDTPRYERVKTRHETHKSGVKAVKRMLEQRGVAFECVERHALTEESVRGHDLIVALGGDGTTLISAHHVRDAKVPILGINTDPATKDELTKMYLTNACVDERRSTGHLCAANRFDAETVLDGALRGTLKPTRLARIRTVLNGKVLEPALNDVLIAHPSPAAVSRYSVRLPPTARGGDGYDESAKRFFHVRSSGVRTCTASGSTAAMYSAGGEIMPHDSMSMQYMDREPIYYDHAPPPSVGHGYYERGDALSFRWNSRVGTIYIDGAHVKHDVVLGDDVEMSTDAPELSLFVSKWFVEARRVRTGLDRVFKTRENWGRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTU3</accession>
    <name>A4RTU3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_30385</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416845.1">
        <property type="nucleotide sequence ID" value="XM_001416808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTU3"/>
    <dbReference type="GeneID" id="5001042"/>
    <dbReference type="Gramene" id="ABO95138">
        <property type="protein sequence ID" value="ABO95138"/>
        <property type="gene ID" value="OSTLU_30385"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30385"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_596411_0_0_1"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF46">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672890" description="Protein DETOXIFICATION" evidence="8">
        <location>
            <begin position="19"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="365"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="459" mass="48340" checksum="4EAE852749DE766C" modified="2007-05-15" version="1">MCAALAMALALVSGTASAIACAATLTPSARGAFRLTPEVAALANEMFPWVLGATPFAMAFESAMGTVCGIGRVETATRWSAGKAAADAAATLAALGLGRGDAAKMRWIGVGTFAVSVAQAGLGWWLVSTTTPRGWDEPLAPRATSARRLGAAETFGFLANGASMVARSILLQSSFFVAVVVAARNLEPSGLAAHHIVVSLWMVCSYVVDGFATCATVIGSRLFGAGRKDELVRLSHTLVAWGVVTGFVFSAALVAGESAIPSVFTRDAKTKEALLGSGVWRVLVLAQPINAAVFVYDGFIYATHSFSFVREVMATGVGLVFLPTLYLANRPLVSLKGIWTAKLALNAWRVAWLAGRVHVWLPRQEMSPRDDNGENESESDSDDDEEAAHYEPLLPGNESEEDVESVTPQTNDVQYESSLKPSKIKAKGLSPIRTPELAMARASSLRASAGEFAPSSSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTZ7</accession>
    <name>A4RTZ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_33894</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Component of the 19S regulatory particle (RP/PA700) base subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700). The RP/PA700 complex is composed of at least 17 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416582.1">
        <property type="nucleotide sequence ID" value="XM_001416545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTZ7"/>
    <dbReference type="STRING" id="436017.A4RTZ7"/>
    <dbReference type="GeneID" id="5000920"/>
    <dbReference type="Gramene" id="ABO94875">
        <property type="protein sequence ID" value="ABO94875"/>
        <property type="gene ID" value="OSTLU_33894"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33894"/>
    <dbReference type="eggNOG" id="KOG0728">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_2_1_1"/>
    <dbReference type="OMA" id="REPAVIF"/>
    <dbReference type="OrthoDB" id="1154031at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000006">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000044">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="173"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="398" mass="44302" checksum="0351CE3ECE3D267E" modified="2007-05-15" version="1">MDVDARPQTGLRAYYDAKIEELEVRLRDKTQNLRRLEAQRNELNGRVRSLREELHMLQEPGSYVGEVVKVMGKKKVLVKVHPEGKYVCDMDKSIDVTKLTAGTRVALRNDSYTLHVILPSNIDPLVSLMKVEKVPDSTFDMIGGLDQQVKEIKEVVELPIKHPELFDALGIAQPKGVILYGPPGTGKTLLARAVAHHTDCCFIRVSGSELVQKYIGEGARMVRELFVMAREHAPSILFMDEVDSIGSARDGGGGGGGDSEVQRTMLELLNQLDGFEATNKIKVIMATNRLDILDQALLRPGRIDRKIEFPNPSEDSRVDILKIHSRKMNLVRGIDLKKIASKMGGASGAESKAVCTEAGMFALRERRVHVTQEDFEMAVSKVMQKDSEKNISVKKLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU38</accession>
    <name>A4RU38_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bis(5'-adenosyl)-triphosphatase</fullName>
            <ecNumber evidence="7">3.6.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_14523</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = AMP + ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13893"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.6.1.29" evidence="7"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416605.1">
        <property type="nucleotide sequence ID" value="XM_001416568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU38"/>
    <dbReference type="STRING" id="436017.A4RU38"/>
    <dbReference type="GeneID" id="5001016"/>
    <dbReference type="Gramene" id="ABO94898">
        <property type="protein sequence ID" value="ABO94898"/>
        <property type="gene ID" value="OSTLU_14523"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14523"/>
    <dbReference type="eggNOG" id="KOG3379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_7_1_1"/>
    <dbReference type="OMA" id="DAIYGMM"/>
    <dbReference type="OrthoDB" id="680339at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047627">
        <property type="term" value="F:adenylylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047710">
        <property type="term" value="F:bis(5'-adenosyl)-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000011">
        <property type="entry name" value="Fragile histidine triad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051884">
        <property type="entry name" value="Bis(5'-adenosyl)-TPase_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243:SF1">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="10"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="6">
        <location>
            <begin position="103"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="3">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="98"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for induction of apoptosis" evidence="5">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="17629" checksum="03A5722A3A14CDFB" modified="2007-05-15" version="1">MSSDARAHGDGVSFGPIAIPGAQVFYETSQTFALVNLKPVVPGHVLVCPRRSTPKFTDLSDEEISDLWRTVAVIQRALEREHDTSSSTLAIQDGPLAGQTVPHVHVHVLPRRVGDFARNDDVYDDLERWNADGSKALDDDRPPRSAEEMRAEADALRALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU91</accession>
    <name>A4RU91_OSTLU</name>
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        <recommendedName>
            <fullName evidence="7">Translation initiation factor IF-2, chloroplastic</fullName>
        </recommendedName>
    </protein>
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        <name evidence="10" type="primary">CIF2</name>
        <name evidence="10" type="ORF">OSTLU_118781</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001416594.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RU91"/>
    <dbReference type="GeneID" id="5000999"/>
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        <property type="protein sequence ID" value="ABO94924"/>
        <property type="gene ID" value="OSTLU_118781"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_118781"/>
    <dbReference type="eggNOG" id="KOG1145">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006301_5_1_1"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
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        <property type="project" value="EnsemblPlants"/>
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        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="mtIF2_IVc"/>
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    </dbReference>
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        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-G-like_DII"/>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
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        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
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        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="508"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="212"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="267"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1028"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1028"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1053" mass="112053" checksum="645C7745B25F27C4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUH7</accession>
    <name>A4RUH7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_9941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO95255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUH7"/>
    <dbReference type="STRING" id="436017.A4RUH7"/>
    <dbReference type="GeneID" id="5000657"/>
    <dbReference type="Gramene" id="ABO95255">
        <property type="protein sequence ID" value="ABO95255"/>
        <property type="gene ID" value="OSTLU_9941"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9941"/>
    <dbReference type="eggNOG" id="ENOG502S1B9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064548_3_0_1"/>
    <dbReference type="OMA" id="HRQNCAS"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_bL28_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="8591" checksum="7B6A4BDB3E83B52A" modified="2007-05-15" version="1" fragment="single">RKCMLTGKKANNGRTVSFSHIRNKTLQQVNLQYKRIYWPEQKRYVRLRISTNALKTLNKLGLEEMAKRAGLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUM5</accession>
    <name>A4RUM5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_30672</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416698.1">
        <property type="nucleotide sequence ID" value="XM_001416661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUM5"/>
    <dbReference type="STRING" id="436017.A4RUM5"/>
    <dbReference type="GeneID" id="5000935"/>
    <dbReference type="Gramene" id="ABO94991">
        <property type="protein sequence ID" value="ABO94991"/>
        <property type="gene ID" value="OSTLU_30672"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30672"/>
    <dbReference type="HOGENOM" id="CLU_476849_0_0_1"/>
    <dbReference type="OMA" id="YCHRFTH"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15517">
        <property type="entry name" value="PHD_TCF19_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="139"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="223"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="333"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="63740" checksum="E5799A65D8E4891E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV04</accession>
    <name>A4RV04_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416758.1">
        <property type="nucleotide sequence ID" value="XM_001416721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV04"/>
    <dbReference type="GeneID" id="5000888"/>
    <dbReference type="Gramene" id="ABO95051">
        <property type="protein sequence ID" value="ABO95051"/>
        <property type="gene ID" value="OSTLU_30804"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30804"/>
    <dbReference type="HOGENOM" id="CLU_1542631_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19136" checksum="56280AE38BCDD92E" modified="2007-05-15" version="1">MKLSDDAAPGSIASVRASTRASRKRSRDVVIESAQLFVKSSRRRAAVSDDEDESDVVATVRAADGGDDATPPARRETPVESSLVCAPRTRRETKDHAFRKANEAQSALLGTLCEDALWKVCEFLPAKDLASLECASSYFHRPMRRADRGLGIAERVARVRIRGAQMADMPPFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV06</accession>
    <name>A4RV06_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5B</fullName>
            <ecNumber evidence="3">3.6.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Translation initiation factor IF-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_48964</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417054.1">
        <property type="nucleotide sequence ID" value="XM_001417017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV06"/>
    <dbReference type="STRING" id="436017.A4RV06"/>
    <dbReference type="GeneID" id="5000918"/>
    <dbReference type="Gramene" id="ABO95347">
        <property type="protein sequence ID" value="ABO95347"/>
        <property type="gene ID" value="OSTLU_48964"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48964"/>
    <dbReference type="eggNOG" id="KOG1144">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002656_3_3_1"/>
    <dbReference type="OMA" id="FRQSKPA"/>
    <dbReference type="OrthoDB" id="4928at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
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        <property type="term" value="F:translation initiation factor activity"/>
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        <property type="entry name" value="aeIF5B_II"/>
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        <property type="entry name" value="IF2_aeIF5B_IV"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EFTU-type"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
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        <property type="entry name" value="TIF_IF2"/>
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        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
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        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
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        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
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        <property type="entry name" value="PRK04004.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="13">
        <location>
            <begin position="24"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="623" mass="69515" checksum="F367685AAA2E851D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV36</accession>
    <name>A4RV36_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_4583</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416775.1">
        <property type="nucleotide sequence ID" value="XM_001416738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV36"/>
    <dbReference type="STRING" id="436017.A4RV36"/>
    <dbReference type="GeneID" id="5000700"/>
    <dbReference type="KEGG" id="olu:OSTLU_4583"/>
    <dbReference type="eggNOG" id="ENOG502QQ98">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029101_3_1_1"/>
    <dbReference type="OMA" id="QDEHAAC"/>
    <dbReference type="OrthoDB" id="204498at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000164">
        <property type="entry name" value="23S rRNA methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="23S RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544:SF8">
        <property type="entry name" value="RADICAL SAM SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01062">
        <property type="entry name" value="methyltransferase_(Class_A)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="52"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="298" mass="31904" checksum="686589B5A652157B" modified="2007-05-15" version="1" fragment="single">LPRAVVDALRANFVLYTTKVRHESRSGDGTTTKMIVELAGGDVVEACVMRHAKGRTTLCVSSQVGCKMGCTFCATGTLGELGNLSAGEICEQLAHASRGDAVRNVVFMGMGEPLNNYRNVIDAIEAMTSDKGFGLSPAKITVSTVGVIPRMRTLRRDAPGTRLALSLHAPNQALRQKIVPTATAYKLEDLMATLDEHMASGPKMKTMIEYCVLGGVNDDEACARELGALLRGKEVIVNLIPLNPTDTPAGHVPPTREAVQKMLEILTSPEFDLFTTVRHEMGQDIAGACGQLALKTPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV42</accession>
    <name>A4RV42_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_45085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416777.1">
        <property type="nucleotide sequence ID" value="XM_001416740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV42"/>
    <dbReference type="STRING" id="436017.A4RV42"/>
    <dbReference type="GeneID" id="5000782"/>
    <dbReference type="Gramene" id="ABO95070">
        <property type="protein sequence ID" value="ABO95070"/>
        <property type="gene ID" value="OSTLU_45085"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45085"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_6_1"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001092">
        <property type="entry name" value="ATP-binding cassette sub-family F member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001197">
        <property type="entry name" value="Putative ATP-binding cassette family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF14">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="18"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="346"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="533" mass="59242" checksum="453020078FB65C0F" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV70</accession>
    <name>A4RV70_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_30868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SBNO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416791.1">
        <property type="nucleotide sequence ID" value="XM_001416754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="5000709"/>
    <dbReference type="Gramene" id="ABO95084">
        <property type="protein sequence ID" value="ABO95084"/>
        <property type="gene ID" value="OSTLU_30868"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30868"/>
    <dbReference type="eggNOG" id="KOG1513">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000212_2_1_1"/>
    <dbReference type="OMA" id="CHMTLEL"/>
    <dbReference type="OrthoDB" id="421838at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026937">
        <property type="entry name" value="SBNO_Helicase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026741">
        <property type="entry name" value="SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039187">
        <property type="entry name" value="SNO_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12706:SF30">
        <property type="entry name" value="PROTEIN STRAWBERRY NOTCH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12706">
        <property type="entry name" value="STRAWBERRY NOTCH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13872">
        <property type="entry name" value="AAA_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13871">
        <property type="entry name" value="Helicase_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Strawberry notch AAA" evidence="5">
        <location>
            <begin position="91"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Strawberry notch helicase C" evidence="4">
        <location>
            <begin position="920"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="673"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="847"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="630"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="687"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="703"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="847"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1487" mass="165650" checksum="7B0C6E16DCEF1C77" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVN1</accession>
    <name>A4RVN1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-specific adenosine deaminase 2</fullName>
            <ecNumber evidence="3">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_37349</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>adenosine(34) in tRNA + H2O + H(+) = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="3"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417171.1">
        <property type="nucleotide sequence ID" value="XM_001417134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVN1"/>
    <dbReference type="STRING" id="436017.A4RVN1"/>
    <dbReference type="GeneID" id="5001309"/>
    <dbReference type="Gramene" id="ABO95464">
        <property type="protein sequence ID" value="ABO95464"/>
        <property type="gene ID" value="OSTLU_37349"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37349"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025810_3_2_1"/>
    <dbReference type="OMA" id="VCENECK"/>
    <dbReference type="OrthoDB" id="408702at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF179">
        <property type="entry name" value="TRNA(ADENINE(34)) DEAMINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="170" mass="18079" checksum="E2E9540318FEC40E" modified="2007-05-15" version="1">MRRALALALDAGSQGEVPIAAVLVDATTGEVVAEAANRCERDGDPTAHAEMLLIRLGAEKLGGWRHLKRTRMYVTLEPCAMCAGAILQSRVGGVTYGARNALLGADGSWAALLRNEDVGGSERAPVRAHPFTPDLDVKGGVLAEETGEAMREFFRRRRTLGAYDGETASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVP5</accession>
    <name>A4RVP5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PAFC3501</name>
        <name evidence="6" type="ORF">OSTLU_14940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417144.1"/>
    </dbReference>
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    <dbReference type="Gramene" id="ABO95474">
        <property type="protein sequence ID" value="ABO95474"/>
        <property type="gene ID" value="OSTLU_14940"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14940"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006386_1_0_1"/>
    <dbReference type="OMA" id="EHWLTIA"/>
    <dbReference type="OrthoDB" id="343875at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
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        <property type="entry name" value="Ctr9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027:SF2">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="461"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="758"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="929"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="488"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="929"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1004"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1059" mass="116548" checksum="B84977A0696892FF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVS1</accession>
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        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_9763</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417196.1">
        <property type="nucleotide sequence ID" value="XM_001417159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVS1"/>
    <dbReference type="STRING" id="436017.A4RVS1"/>
    <dbReference type="GeneID" id="5001453"/>
    <dbReference type="Gramene" id="ABO95489">
        <property type="protein sequence ID" value="ABO95489"/>
        <property type="gene ID" value="OSTLU_9763"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9763"/>
    <dbReference type="eggNOG" id="ENOG502T0VM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_204273_0_0_1"/>
    <dbReference type="OrthoDB" id="1642657at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14702">
        <property type="entry name" value="bZIP_plant_GBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045314">
        <property type="entry name" value="bZIP_plant_GBF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="65" mass="7446" checksum="0303FCBFF92A8765" modified="2007-05-15" version="1" fragment="single">RRKIANRESAKRSKIRKKAEDAKLLSAAETLLQDSASMRKTITDLQKKVDTLYAENVKLRMKLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVU0</accession>
    <name>A4RVU0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_36819</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417467.1">
        <property type="nucleotide sequence ID" value="XM_001417430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVU0"/>
    <dbReference type="STRING" id="436017.A4RVU0"/>
    <dbReference type="GeneID" id="5001594"/>
    <dbReference type="Gramene" id="ABO95760">
        <property type="protein sequence ID" value="ABO95760"/>
        <property type="gene ID" value="OSTLU_36819"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36819"/>
    <dbReference type="eggNOG" id="KOG0667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_5_15_1"/>
    <dbReference type="OMA" id="CAYFTLA"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14133">
        <property type="entry name" value="PKc_DYRK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000380">
        <property type="entry name" value="Serine/threonine-protein kinase ppk15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF124">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="92"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="395" mass="44667" checksum="1B7AAF1B0F6A90DE" modified="2007-05-15" version="1">MKANAEQTTSAEKKTRVLDRGESFTFGDVPAVDADDGLETPIPQGWVDSERDAASNAFEAFHLKVFHQGKKTGFQDSKDFIVKHGDVVANRYKIIEGIGRAAFSKTVRAHDLQTNTPVCLKIVSNNKDHVDQGLDEIKLLRLINAKDPNDTHGLLRMFDFFYFKEHLFIVSELLRANLYEFQKYNAETAETPYFTLSRVRCIAKQVLESLTFLHSLDLIHCDLKPENILMKSYADCSVKLIDFGSSCFTTDTLTSYAQSRAYRAPEVIIGAKYSQKIDVWSLGCILAELYSGRMLFRNSSVPSLLARMVSIRGPFDTKLLARGTQSHKYFTKQGFLHEIEEMSGTMSILRPKRTCLKTRLGAKDDVFIDFLEKLLVVDPEARLSASEALQHPWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVW7</accession>
    <name>A4RVW7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417482.1">
        <property type="nucleotide sequence ID" value="XM_001417445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVW7"/>
    <dbReference type="SMR" id="A4RVW7"/>
    <dbReference type="GeneID" id="5001324"/>
    <dbReference type="Gramene" id="ABO95775">
        <property type="protein sequence ID" value="ABO95775"/>
        <property type="gene ID" value="OSTLU_24393"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24393"/>
    <dbReference type="eggNOG" id="KOG2088">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_331863_0_0_1"/>
    <dbReference type="OMA" id="MHIVAMP"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023:SF6">
        <property type="entry name" value="LIPASE CLASS 3 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023">
        <property type="entry name" value="LIPASE CLASS 3 PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="190"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="694" mass="76750" checksum="86DFF45786E6242C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-05" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW83</accession>
    <name>SECA_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein translocase subunit SecA, chloroplastic</fullName>
            <ecNumber evidence="1">7.4.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">secA</name>
        <name evidence="5" type="ORF">OSTLU_36933</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a central role in coupling the hydrolysis of ATP to the transfer of proteins across the thylakoid membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + chloroplast-proteinSide 1 = ADP + phosphate + chloroplast-proteinSide 2.</text>
            <dbReference type="EC" id="7.4.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast stroma</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">A minor fraction is associated with the chloroplast thylakoid membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417281.1">
        <property type="nucleotide sequence ID" value="XM_001417244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW83"/>
    <dbReference type="SMR" id="A4RW83"/>
    <dbReference type="STRING" id="436017.A4RW83"/>
    <dbReference type="EnsemblPlants" id="ABO95574">
        <property type="protein sequence ID" value="ABO95574"/>
        <property type="gene ID" value="OSTLU_36933"/>
    </dbReference>
    <dbReference type="GeneID" id="5001476"/>
    <dbReference type="Gramene" id="ABO95574">
        <property type="protein sequence ID" value="ABO95574"/>
        <property type="gene ID" value="OSTLU_36933"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36933"/>
    <dbReference type="eggNOG" id="ENOG502QS7I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005314_3_0_1"/>
    <dbReference type="OMA" id="MVHYDVQ"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016464">
        <property type="term" value="F:chloroplast protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17928">
        <property type="entry name" value="DEXDc_SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1440.10:FF:000003">
        <property type="entry name" value="Preprotein translocase SecA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3060.10:FF:000003">
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    </dbReference>
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        <property type="entry name" value="SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM"/>
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    </dbReference>
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    <dbReference type="PRINTS" id="PR00906">
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    </dbReference>
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    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0934">Plastid</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0793">Thylakoid</keyword>
    <keyword id="KW-0809">Transit peptide</keyword>
    <keyword id="KW-1278">Translocase</keyword>
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    <keyword id="KW-0813">Transport</keyword>
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        <location>
            <begin position="1"/>
            <end status="unknown"/>
        </location>
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            <end position="932"/>
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            <begin position="632"/>
            <end position="653"/>
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            <end position="641"/>
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    <feature type="binding site" evidence="2">
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            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
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        <source>
            <dbReference type="UniProtKB" id="Q41062"/>
        </source>
    </evidence>
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    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO95574.1"/>
        </source>
    </evidence>
    <sequence length="932" mass="105089" checksum="36BFEB755A82A2D6" modified="2007-05-15" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWC6</accession>
    <name>A4RWC6_OSTLU</name>
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        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="5" type="ORF">OSTLU_31292</name>
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    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31292"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR33472:SF28">
        <property type="entry name" value="BROMO AND FHA DOMAIN-CONTAINING PROTEIN DDB_G0267958"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33472">
        <property type="entry name" value="OS01G0106600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673029" description="EF-hand domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="4003"/>
        </location>
    </feature>
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        <location>
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            <end position="3972"/>
        </location>
    </feature>
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        <location>
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            <end position="1876"/>
        </location>
    </feature>
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        <location>
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            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="1367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="1604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
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            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1544"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1773"/>
            <end position="1801"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="4003" mass="440779" checksum="9CC20A17974B4E1C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWR7</accession>
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        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">OSTLU_87137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
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                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
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            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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        <property type="gene ID" value="OSTLU_87137"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_520145_0_0_1"/>
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    <dbReference type="OrthoDB" id="2020517at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035368">
        <property type="term" value="F:selenocysteine insertion sequence binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
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        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
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    <dbReference type="PANTHER" id="PTHR13284:SF4">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR13284">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="524" mass="57915" checksum="92745BA39348868B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWV7</accession>
    <name>A4RWV7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="4">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_10425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="4"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417643.1">
        <property type="nucleotide sequence ID" value="XM_001417606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWV7"/>
    <dbReference type="STRING" id="436017.A4RWV7"/>
    <dbReference type="GeneID" id="5002153"/>
    <dbReference type="KEGG" id="olu:OSTLU_10425"/>
    <dbReference type="eggNOG" id="KOG2698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_3_1_1"/>
    <dbReference type="OMA" id="CEHMCMS"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000001">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="8">
        <location>
            <begin position="3"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="20944" checksum="504C4E0F9827B127" modified="2007-05-15" version="1" fragment="single">LEGCVREILRALGEDVEREGLLDTPSRVAKALMFATRGYDACATVALGTALFHETGMANAMRTTTTNEIANGTHDMVLVRDIPVFSTCAETFMPFYGVIHVGYAPNAGVIVGLSKLARVAEVYARRLQTPDGLQVQERLTRDVAEEVSKLTGGLGVMVAARAAHLCMVSRGVEKPGSSTCTVTKLGRFASEPALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXE4</accession>
    <name>A4RXE4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417985.1">
        <property type="nucleotide sequence ID" value="XM_001417948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXE4"/>
    <dbReference type="STRING" id="436017.A4RXE4"/>
    <dbReference type="GeneID" id="5001859"/>
    <dbReference type="Gramene" id="ABO96278">
        <property type="protein sequence ID" value="ABO96278"/>
        <property type="gene ID" value="OSTLU_31665"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31665"/>
    <dbReference type="HOGENOM" id="CLU_304264_0_0_1"/>
    <dbReference type="OMA" id="VEMPTEG"/>
    <dbReference type="OrthoDB" id="435297at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF7">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="762"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="95"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="791"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="812" mass="87794" checksum="D779FEEB9174C681" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXJ6</accession>
    <name>A4RXJ6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DMT family transporter: UDP-galactose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_15438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417765.1">
        <property type="nucleotide sequence ID" value="XM_001417728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXJ6"/>
    <dbReference type="GeneID" id="5001803"/>
    <dbReference type="Gramene" id="ABO96058">
        <property type="protein sequence ID" value="ABO96058"/>
        <property type="gene ID" value="OSTLU_15438"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15438"/>
    <dbReference type="eggNOG" id="KOG2234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046494_0_0_1"/>
    <dbReference type="OMA" id="CYYFLNP"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005463">
        <property type="term" value="F:UDP-N-acetylgalactosamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904293">
        <property type="term" value="P:negative regulation of ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902183">
        <property type="term" value="P:regulation of shoot apical meristem development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990569">
        <property type="term" value="P:UDP-N-acetylglucosamine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="33395" checksum="BD2AAD2DE01E6908" modified="2007-05-15" version="1">MAPTRVADARRRGPHARGVALFVALALQYASQPFLRARYAANARASALVLSVEIAKATLCACALLRRRETRGALRRASARSLLASGAPAAVYAAQNVLLQRGARALDGVTFNCLNQTKLASAAAFLWLGGARQSRAQCLALVGTLAAAVNLFGGETAASGGGGAASAAARAAGATSVLVASALSGLSGAMCQFALQGSEKLPAMMTLEMAITGVPMVLLAERVAAGDEFRLSAVYESWTAWALVPVLSSAIGGILVGEITKRLGSIAKGFAVTCGLVLTGVFQSVFAGAAPPRAHVVSLIVIVISTWVHTAFPPVEKRKKKRKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXR3</accession>
    <name>A4RXR3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_38832</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418039.1">
        <property type="nucleotide sequence ID" value="XM_001418002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXR3"/>
    <dbReference type="STRING" id="436017.A4RXR3"/>
    <dbReference type="GeneID" id="5001897"/>
    <dbReference type="Gramene" id="ABO96332">
        <property type="protein sequence ID" value="ABO96332"/>
        <property type="gene ID" value="OSTLU_38832"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38832"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_7_35_1"/>
    <dbReference type="OMA" id="CIITESA"/>
    <dbReference type="OrthoDB" id="536504at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF289">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE VIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="80"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="372" mass="40257" checksum="9D07899AD073D1B3" modified="2007-05-15" version="1">MLPGQCFRTKDYDLEGVVARAGDDTARINTGSHPSRRGAKKTTNGDLFEASLATYAESAKDANTVSDDDDDVVEIHLSNIKLGRLIGQGAYGAVYVGKWNKRVVAVKKLHGVPPGAGKSDLKTFVREVAVLSAVRHPKIVRMFGACLKLPHLCIVEEMMDGGSLHALLHQDKQYDVSLDDVVRIALDVAQAMAYLHSRCIVHRDLKSHNVLLNGRGAKVADFGIARALERTLLSAGGSATSAGGASAGTAGTPAYMAPELFHGDADAVTTKCDVFSFSVLLWESLARSIPWEWFANHMQIIFAVAIQSQRLPLDAPPFARDDVVVRALVDDVIVPAWQTAPDARPDFTELIVVLNRALRELLAESRVAVDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY03</accession>
    <name>A4RY03_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418085.1">
        <property type="nucleotide sequence ID" value="XM_001418048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY03"/>
    <dbReference type="GeneID" id="5002000"/>
    <dbReference type="Gramene" id="ABO96378">
        <property type="protein sequence ID" value="ABO96378"/>
        <property type="gene ID" value="OSTLU_31878"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31878"/>
    <dbReference type="HOGENOM" id="CLU_1386220_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="197" mass="22161" checksum="E665151E48A5B067" modified="2007-05-15" version="1">MRRDVGAAKSEAAKFRGEAMRERARANFEAAEKKKARAEVAKLEEALEEARRGAGAAEVVRMAKDAANEGVKRAKTLVRDAKPLIEDGMRKAAPALKNAGERAKRGYARQIRNVQSNLAPVRRKMKAKMKQIDLLKPYATDRHINTLFQATYTLILALCVHRTLGVLYRFAFGRRSRSVPRHVRSKSVELRPLSPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY82</accession>
    <name>A4RY82_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DEAD/DEAH box helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_38435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
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    <dbReference type="Gramene" id="ABO96418">
        <property type="protein sequence ID" value="ABO96418"/>
        <property type="gene ID" value="OSTLU_38435"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG4150">
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    <dbReference type="OMA" id="PEFICTS"/>
    <dbReference type="OrthoDB" id="18781at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="ATP-DEPENDENT HELICASE"/>
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    </dbReference>
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        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
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    </dbReference>
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        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Helicase_C"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="52"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="269"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO96418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="758" mass="82714" checksum="9461C8C5482775DE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYA0</accession>
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        <recommendedName>
            <fullName evidence="3">GHMP kinase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_40817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418132.1">
        <property type="nucleotide sequence ID" value="XM_001418095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYA0"/>
    <dbReference type="STRING" id="436017.A4RYA0"/>
    <dbReference type="GeneID" id="5002294"/>
    <dbReference type="Gramene" id="ABO96425">
        <property type="protein sequence ID" value="ABO96425"/>
        <property type="gene ID" value="OSTLU_40817"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40817"/>
    <dbReference type="eggNOG" id="ENOG502QPXH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050132_0_0_1"/>
    <dbReference type="OMA" id="NHMDELG"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053034">
        <property type="entry name" value="Glucuronokinase-like"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
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        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
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        <property type="entry name" value="WITH PUTATIVE URIDYL PYROPHOSPHORYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38710:SF1">
        <property type="entry name" value="WITH PUTATIVE URIDYL PYROPHOSPHORYLASE-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="3">
        <location>
            <begin position="132"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="41669" checksum="801DC839536F8087" modified="2007-05-15" version="1">MYSDGDSTHVAVTDAQSPGLRRGIATTLERLRVVTPIGDVITKRAYARVGLVGNPSDAYGGKCVAFTISNFFAEASLRRTPSSKRVTFAPGPYDGNAFDSFDALSTHVSQHGVDGGVRLLKSLCCNLMRYCESTKQRIDTSCGFEMSYTSNIPKQTGLSGSSAIVIAAMRCLLEMYRINISLDDQTELALRVERDVGINAGPMDRVAQVYEGAVFMDFTKPRASTACGWRIHGEYTRVETDELPPLYLVWAKDNESESSRIHADVRRRWDAGDADVATSMSRLASLADDVFKAMATRQINVEELKTSIDTNFDIRRALFGDQAIGALNVTLVSVCRERAGCAAKFAGSGGACVVVCENDRARALKEACDAHGFEVERVVVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYJ2</accession>
    <name>A4RYJ2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418172.1">
        <property type="nucleotide sequence ID" value="XM_001418135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYJ2"/>
    <dbReference type="STRING" id="436017.A4RYJ2"/>
    <dbReference type="GeneID" id="5002359"/>
    <dbReference type="Gramene" id="ABO96465">
        <property type="protein sequence ID" value="ABO96465"/>
        <property type="gene ID" value="OSTLU_15687"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15687"/>
    <dbReference type="eggNOG" id="ENOG502QRTM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_765903_0_0_1"/>
    <dbReference type="OMA" id="SCYLIAM"/>
    <dbReference type="OrthoDB" id="64928at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36749">
        <property type="entry name" value="F7O18.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36749:SF1">
        <property type="entry name" value="F7O18.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="362" mass="39954" checksum="54998CDEE03752BD" modified="2007-05-15" version="1">MGLYDDLPDAKPRATTASTARDGDASDDASIRDAKRAKRATGDAGERSEDAQKVQLRDDATVAAPSKAATTKDALQRIAQHLLKPEKFVKASGLLKKLLMSEACDRGDAKALFACLENAMTPTPKARALRAETRLDYEELFEIVAAFSPLIFNAKQKRKLEVWSTYARRINALRTDDSFEFTKAVKAIQEVVDRVDSYVEPPGVIEDDDIEIPPAPEGASEEEAMEMATQYARSIKAERAAEIEQLAVVDELREALIDALEFTSSLYGRTWSQTTIDMMSNFFHERRPKFSPTSQERIVKIWDDLRKKKHARSLTSAGDKVSMTSFERDQARAAGSQVSARGSVGAENVKDGRGESAAKMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYK0</accession>
    <name>A4RYK0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_9208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418406.1">
        <property type="nucleotide sequence ID" value="XM_001418369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYK0"/>
    <dbReference type="STRING" id="436017.A4RYK0"/>
    <dbReference type="GeneID" id="5002471"/>
    <dbReference type="Gramene" id="ABO96699">
        <property type="protein sequence ID" value="ABO96699"/>
        <property type="gene ID" value="OSTLU_9208"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9208"/>
    <dbReference type="eggNOG" id="KOG0190">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_3_1"/>
    <dbReference type="OMA" id="CKQLAPH"/>
    <dbReference type="OrthoDB" id="74910at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="80" mass="8839" checksum="B0F6446EFD2DD029" modified="2007-05-15" version="1" fragment="single">VDLSETNFDEVVGRGTPVLVKVYAEWCKHCVALAPVWGEVARELEGELFVGRVDGPKNRLLLKRIGAKAYPTIALFKNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYQ2</accession>
    <name>A4RYQ2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418432.1">
        <property type="nucleotide sequence ID" value="XM_001418395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYQ2"/>
    <dbReference type="GeneID" id="5002225"/>
    <dbReference type="Gramene" id="ABO96725">
        <property type="protein sequence ID" value="ABO96725"/>
        <property type="gene ID" value="OSTLU_32108"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32108"/>
    <dbReference type="HOGENOM" id="CLU_2077044_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="118" mass="12557" checksum="89F60B62B79A1186" modified="2007-05-15" version="1">MQLSAFDGDKTRKTRATAEEMAREAEQMEELSVFRAVSGLVAAAAGGGLVFALGAGAVAGVASGLASALGMVRDGKAQRERERDRETLRYELSMASGWGRQARRRRADIQAKLDALGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ74</accession>
    <name>A4RZ74_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_41082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418279.1">
        <property type="nucleotide sequence ID" value="XM_001418242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ74"/>
    <dbReference type="STRING" id="436017.A4RZ74"/>
    <dbReference type="GeneID" id="5002488"/>
    <dbReference type="Gramene" id="ABO96572">
        <property type="protein sequence ID" value="ABO96572"/>
        <property type="gene ID" value="OSTLU_41082"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41082"/>
    <dbReference type="eggNOG" id="KOG2045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006038_3_1_1"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09897">
        <property type="entry name" value="H3TH_FEN1-XPG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="509" mass="58113" checksum="2D44D21F48379B5C" modified="2007-05-15" version="1" fragment="single">MGVPKFFRWLAERYPLLQQEIAGNQIPGIDNLYLDMNGVIHNCSHGAGTDVNTRMTEDEMMSKVFAYLDHLFRMTRPNKMLYMAIDGVAPRAKMNQQRSRRFRSAAEAAKDREEARARGEPEPEGEPFDSNCITPGTEFMARLTEHLKFYVRKKQTEDPLWAKVTVILSGHEVRGEGEHKIMEHIRWARTQPDWEPNQTHCLYGLDADLIMLALVTHEPHFCLLREVVKFGGGEKGQPSREILSNPTDDGFILLHIGLLREYLDLEFREKNLPFGYELERVIDDFILLCMLVGNDFLPALPTLNIAEGALNTLFKVYHDTLPMLGGYITGDEGGGTFNPELSADPTMMNAAKRALILEGGEEGLQAWKDTYYREKLGLKIGEAAPLGEIRQAYFDGLNWVLRYYYRGVASWTWYYPYHYAPMASDLCAGMGGLTSEFDYGEPFKPFEQLMAVQPPSSSKLLPEPFRHFMEDPQSPLAEFFPEDIKVDFEGKRNDWEGVVLLPFLDADRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZL7</accession>
    <name>A4RZL7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418817.1">
        <property type="nucleotide sequence ID" value="XM_001418780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZL7"/>
    <dbReference type="GeneID" id="5002614"/>
    <dbReference type="Gramene" id="ABO97110">
        <property type="protein sequence ID" value="ABO97110"/>
        <property type="gene ID" value="OSTLU_32433"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32433"/>
    <dbReference type="HOGENOM" id="CLU_1484380_0_0_1"/>
    <dbReference type="OMA" id="CKMLRAS"/>
    <dbReference type="OrthoDB" id="10266961at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20276" checksum="46259588D35957B2" modified="2007-05-15" version="1">MARDDAAPASGDARLACVDFDLTVLARHSFAERVTVERVEALELRDVEREFVDVECFRAFLEYANRRGMDVKITSFGKYAVIQAYVDRVLGEGAMTRADISTPSRVGVKDGCAVEGGKNRQIEELLREKYGEDAWEKFRGTVVLFDDDERNVEAAIRAGFRATHTPDGLTKAAIQSVFGDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZM1</accession>
    <name>A4RZM1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SNU114 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_35547</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418820.1">
        <property type="nucleotide sequence ID" value="XM_001418783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZM1"/>
    <dbReference type="STRING" id="436017.A4RZM1"/>
    <dbReference type="GeneID" id="5002916"/>
    <dbReference type="Gramene" id="ABO97113">
        <property type="protein sequence ID" value="ABO97113"/>
        <property type="gene ID" value="OSTLU_35547"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35547"/>
    <dbReference type="eggNOG" id="KOG0468">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_11_2_1"/>
    <dbReference type="OMA" id="YIFRPIR"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04098">
        <property type="entry name" value="eEF2_C_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04090">
        <property type="entry name" value="EF2_II_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01683">
        <property type="entry name" value="EF2_IV_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04167">
        <property type="entry name" value="Snu114p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000004">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000029">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000009">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1430.10:FF:000001">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000646">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031950">
        <property type="entry name" value="EFTUD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044121">
        <property type="entry name" value="Snu114_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035655">
        <property type="entry name" value="U5-116kDa_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF6">
        <property type="entry name" value="116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16004">
        <property type="entry name" value="EFTUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="116"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00079027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="974" mass="107477" checksum="76488354F045C231" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZX4</accession>
    <name>A4RZX4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[RNA-polymerase]-subunit kinase</fullName>
            <ecNumber evidence="3">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_35576</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.23" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418643.1">
        <property type="nucleotide sequence ID" value="XM_001418606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZX4"/>
    <dbReference type="STRING" id="436017.A4RZX4"/>
    <dbReference type="GeneID" id="5002962"/>
    <dbReference type="Gramene" id="ABO96936">
        <property type="protein sequence ID" value="ABO96936"/>
        <property type="gene ID" value="OSTLU_35576"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35576"/>
    <dbReference type="eggNOG" id="KOG0659">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="CLESEYF"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="STKc_CDK7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CMGC/CDK/CDK7 protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Putative cyclin-dependent kinase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
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        <property type="entry name" value="CDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="4"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="314"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="314"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="10"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO96936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="42584" checksum="5956DB8A8AF1E620" modified="2007-05-15" version="1">MDRYVKGRTLGEGTFGVVHEARVEATGERVAIKKIRLGKLKEGVNFTAIREIKLLQEIEHEHVIALVDVFAHKKNLNLVFEFCGGDLEMVIRDKTAPLERGEVKSYAMMTLRAVAHCHERWVLHRDLKPNNLLIAPNGCLKLADFGLARIFGSPDRRFTHQVFARWYRAPELLLGSKTYGPGVDIWAVGCIIAELMLRRPFFAGSSDIDQLGKVYAALGTPTETNWPGVSALPDFIEFVYVPPPNLRDTFPNETDEALDLLRKMLEYDPNKRITAAQALEHPYFHTKPAPIPYEQLPKRFVAKEAEANAAAAAAAAAAAGDEEPASPASARQPKTGEKRRLEDTTDSTDPNFRPKLDEEDRESLRKRKGALDAAFADVDGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0M5</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="741" mass="79117" checksum="5B4E8B0C35624218" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0P1</accession>
    <name>A4S0P1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_87859</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase C subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418773.1">
        <property type="nucleotide sequence ID" value="XM_001418736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0P1"/>
    <dbReference type="STRING" id="436017.A4S0P1"/>
    <dbReference type="GeneID" id="5002801"/>
    <dbReference type="Gramene" id="ABO97066">
        <property type="protein sequence ID" value="ABO97066"/>
        <property type="gene ID" value="OSTLU_87859"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87859"/>
    <dbReference type="eggNOG" id="KOG2909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017554_3_0_1"/>
    <dbReference type="OMA" id="VMIWIHV"/>
    <dbReference type="OrthoDB" id="6605928at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009826">
        <property type="term" value="P:unidimensional cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd14785">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1460.10">
        <property type="entry name" value="subunit c (vma5p) of the yeast v-atpase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1180">
        <property type="entry name" value="Vacuolar atp synthase subunit c, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004907">
        <property type="entry name" value="ATPase_V1-cplx_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036132">
        <property type="entry name" value="Vac_ATP_synth_c_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03223">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118203">
        <property type="entry name" value="Vacuolar ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="374" mass="42089" checksum="56B83FC081213DB4" modified="2007-05-15" version="1">MTTTYWLVSLPLRGSSADAAWATLQRHTGGSNDLSLNYKMRCPDLRVGTLDSLLALSDDLVKVNALAEQVVEKVRRQFGELGDATTSERELRVDGESVERYLTTFEWDEAKNPARRALKETVEKLSERLSRIDEEFKLKCGQLATSKNHLNAIVRKVGSGVNAQDLSDKVNPEDLVQTENLTTLVVQVPKLKTEVWTSSYETLASFVVPRSSKIIHVEDDYELRTVVLFRRVVDAFTTAAREIGCTAKEYSHDPEASRAAKSQRGALEQEVVQRRDSLLEWCQISYGEAFSTMMHVCTVRVFVESILRYGLPPDFQAVLMRPNMKHVSKLRKVLNQEFGKDASSHWDDEIGGDEKSGGGLVEDMYSYVSLTMKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0T6</accession>
    <name>A4S0T6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">O-phosphoseryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5 17">2.9.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 17">Selenocysteine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14 17">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15 17">Sep-tRNA:Sec-tRNA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">OSTLU_35440</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 17">Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H2O = L-selenocysteinyl-tRNA(Sec) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:25041"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="Rhea" id="RHEA-COMP:9947"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78551"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17 19">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the SepSecS family.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.2" evidence="5 17"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418795.1">
        <property type="nucleotide sequence ID" value="XM_001418758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0T6"/>
    <dbReference type="STRING" id="436017.A4S0T6"/>
    <dbReference type="GeneID" id="5002858"/>
    <dbReference type="Gramene" id="ABO97088">
        <property type="protein sequence ID" value="ABO97088"/>
        <property type="gene ID" value="OSTLU_35440"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35440"/>
    <dbReference type="eggNOG" id="KOG3843">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022508_0_0_1"/>
    <dbReference type="OMA" id="MSHANDY"/>
    <dbReference type="OrthoDB" id="10263545at2759"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00898"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098621">
        <property type="term" value="F:O-phosphoseryl-tRNA(Sec) selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001717">
        <property type="term" value="P:conversion of seryl-tRNAsec to selenocys-tRNAsec"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019872">
        <property type="entry name" value="Sec-tRNA_Se_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008829">
        <property type="entry name" value="SepSecS/SepCysS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03531">
        <property type="entry name" value="selenium_SpcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12944:SF2">
        <property type="entry name" value="O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12944">
        <property type="entry name" value="SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05889">
        <property type="entry name" value="SepSecS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017689">
        <property type="entry name" value="SepSecS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 17" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10 17 19" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17 19" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="12 17" id="KW-0711">Selenium</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 17 19" id="KW-0820">tRNA-binding</keyword>
    <feature type="binding site" evidence="18">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
        <ligandPart>
            <name>tRNA discriminator base</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
        <ligandPart>
            <name>tRNA acceptor arm</name>
        </ligandPart>
    </feature>
    <feature type="site" description="May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate" evidence="19">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="19">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR017689-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABO97088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="481" mass="51963" checksum="42FA070C4041D95F" modified="2007-05-15" version="1">MDDDLVAAFSANLLSKSYVNQGAQSLRAHDKVFARLLANRRMLGRGLNDVAIEFLVHKLSVMDSNNFIDNVGVGEREGRVFSDMVRRRCYSMTHGIGRSGDITAEQPKACGSSAAHALAQCMARDALRLAGMRDLGKRALVLPLATGMTLTLVLSSLRLMVRNSADGGVDAAAPNVVIWCRLDQKTCVKAATCAGLEIVVIEPVLNGDQLDTNVHAIERAIEDVGVDRLVAVVTSTSCFAPRACDDVETVAKLCEKKNVAHVINNAYGVQSRVLCERVSKAWTVGRVDAVVQSTDKNFMVPVGGAVVCCGKRNEALVEAVARNYPGRASASASMDMFITLLSMGEEHWLRLLDEREKLYDYMHAELSKVAEEEGERMLRTPGNPISMAMTLSCARGISPTMFGSMLFSRCVSGTRVVAPGEVKTVGGIEFHGFGASHSAYPETYFTAAAAIGTTRADVDRFASVLRKTFKDFKKKSQPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S167</accession>
    <name>A4S167_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_32991</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419310.1">
        <property type="nucleotide sequence ID" value="XM_001419273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S167"/>
    <dbReference type="GeneID" id="5003263"/>
    <dbReference type="Gramene" id="ABO97603">
        <property type="protein sequence ID" value="ABO97603"/>
        <property type="gene ID" value="OSTLU_32991"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32991"/>
    <dbReference type="eggNOG" id="ENOG502QS3J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012115_0_0_1"/>
    <dbReference type="OMA" id="VPMNWTE"/>
    <dbReference type="OrthoDB" id="496426at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054481">
        <property type="entry name" value="GWD1_pHisD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47453">
        <property type="entry name" value="PHOSPHOGLUCAN, WATER DIKINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47453:SF1">
        <property type="entry name" value="PHOSPHOGLUCAN, WATER DIKINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22973">
        <property type="entry name" value="GWD1_pHisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-glucan water dikinase phosphohistidine-like" evidence="12">
        <location>
            <begin position="460"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="11">
        <location>
            <begin position="612"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="918" mass="100095" checksum="72CC418D49F8D541" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1C7</accession>
    <name>A4S1C7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_42772</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419127.1">
        <property type="nucleotide sequence ID" value="XM_001419090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1C7"/>
    <dbReference type="STRING" id="436017.A4S1C7"/>
    <dbReference type="GeneID" id="5003292"/>
    <dbReference type="Gramene" id="ABO97420">
        <property type="protein sequence ID" value="ABO97420"/>
        <property type="gene ID" value="OSTLU_42772"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42772"/>
    <dbReference type="eggNOG" id="KOG0242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_2_1_1"/>
    <dbReference type="OMA" id="NVHETIS"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01374">
        <property type="entry name" value="KISc_CENP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000177">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="1"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="346"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="75"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="438" mass="47960" checksum="E54D8FE69021BC65" modified="2007-05-15" version="1" fragment="single">MKTRDDERALGGTNQNLTKARADDFYARQDGASTTYAFDRVFDETSDNRAVYEATTSKIVQNVIGGFNGTVFAYGQTSSGKTHTMHGTKEELGVIPLAVRDVFDAVRRHGSDREFLIRVSYLEIYNEKMMDLFDGAGEDEETSKLSIREDKERGTYVMGLREEVVTTPSQVLALLELGTTRRHVGATNMNAHSSRSHTIFRMIVESRAISGGMQGGADDGAAVLVSTLNLVDLAGSERMSKTGAEGQRAKEGAHINKSLMTLGVVINKLSEGVESKGGHIPYRDSKLTRILQPALGGNSKTAIVCAMTPAASHCEETHSTLKFAQRAKRVVNKATKNEVAANGATNAMLKRQQKEIAALKARLEEEGCAKVDDKAIEALRRRLAEADREKNLMALALEDGEEKAKEREAKISELEAKVKELNDALNEAKARDEEEDPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1E9</accession>
    <name>A4S1E9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419353.1">
        <property type="nucleotide sequence ID" value="XM_001419316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1E9"/>
    <dbReference type="STRING" id="436017.A4S1E9"/>
    <dbReference type="GeneID" id="5003241"/>
    <dbReference type="Gramene" id="ABO97646">
        <property type="protein sequence ID" value="ABO97646"/>
        <property type="gene ID" value="OSTLU_33075"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33075"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_889492_0_0_1"/>
    <dbReference type="OMA" id="HHDINAP"/>
    <dbReference type="OrthoDB" id="496398at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052391">
        <property type="entry name" value="E3_Ligase-Neurotoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24133">
        <property type="entry name" value="ANKYRIN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24133:SF40">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="267"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="338" mass="37469" checksum="426A787FC029DCBA" modified="2007-05-15" version="1">MPRRESSRDARLRRARVAFAPSRVVVIVVIAALTLLRHARRVDAGGFGRSSLYSELQRTYGLGGREADAEHDVVPDPNAREAEPEPEEEKPANLLHVGHRMDHEELRNQFEKFPDHHDINAPLHRSGLTALKHAILVGNDTYVRTVIELGADTNAKLYGGKAIHFNAGSCGQRGSVPILHALLEHGADPIEETDQGYQPIHIAARGWKKYCIPYMQTLLEAEAVDPNARRSTGNLTTPLHEAAHKSSFEMVKVLIDAGADVNAQDADGETPLHKAIRGDHIHAAWGLMSNGADIFIKNKRGIDVEALANLMRADYDTKQMFKQHKESLEKKKAVKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1M9</accession>
    <name>A4S1M9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419393.1">
        <property type="nucleotide sequence ID" value="XM_001419356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1M9"/>
    <dbReference type="GeneID" id="5003231"/>
    <dbReference type="Gramene" id="ABO97686">
        <property type="protein sequence ID" value="ABO97686"/>
        <property type="gene ID" value="OSTLU_33155"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33155"/>
    <dbReference type="HOGENOM" id="CLU_941329_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="32677" checksum="ACFC9568D73F184F" modified="2007-05-15" version="1">MALVGARMKISFGDYARDVSACVVFHDARERHAHHVLCDDGHHMWASFELEATSDGARRRGTLVARNDRMEDVRADVVVLDGEARDRERERGQSEDEATEEDDEDDEGDDDDEDAEEKERRRQRRRASERGLGNGATTTTGRRASDGDVVEDSGAARGAVKPKKAARESRERRRQEGRNKARAAMRVNAVAMNVSTVDPEYGVDADATAKEGARSTRVRVPSKRLLESDELAALRAKRLASDRLANRANTANPRAANTVGIGTNRTNHNDASRRAAERRPADSQSDPTFDPTSTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1N1</accession>
    <name>A4S1N1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanobacterial aminoacyl-tRNA synthetase CAAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419394.1">
        <property type="nucleotide sequence ID" value="XM_001419357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1N1"/>
    <dbReference type="STRING" id="436017.A4S1N1"/>
    <dbReference type="GeneID" id="5003178"/>
    <dbReference type="Gramene" id="ABO97687">
        <property type="protein sequence ID" value="ABO97687"/>
        <property type="gene ID" value="OSTLU_33157"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33157"/>
    <dbReference type="eggNOG" id="ENOG502RZIT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095488_4_0_1"/>
    <dbReference type="OMA" id="KWEAVED"/>
    <dbReference type="OrthoDB" id="2014299at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009515">
        <property type="term" value="C:granal stacked thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090391">
        <property type="term" value="P:granum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097753">
        <property type="term" value="P:membrane bending"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025564">
        <property type="entry name" value="CAAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033344">
        <property type="entry name" value="CURT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222:SF4">
        <property type="entry name" value="PROTEIN CURVATURE THYLAKOID 1A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14159">
        <property type="entry name" value="CAAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanobacterial aminoacyl-tRNA synthetase CAAD" evidence="2">
        <location>
            <begin position="28"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="113" mass="12410" checksum="C3CEE7C5B2E3B25D" modified="2007-05-15" version="1">MTVKPAVALRSTTIARAEKFNADDVLATIADKWEETENKSTVITYVAGATAAVWLSSTLVGAINVVPLLPKIMELVGLGYSTWFAYRYVLFKESRQELVEQVDALVSRVSGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1S3</accession>
    <name>A4S1S3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_33202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419417.1">
        <property type="nucleotide sequence ID" value="XM_001419380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1S3"/>
    <dbReference type="STRING" id="436017.A4S1S3"/>
    <dbReference type="GeneID" id="5003112"/>
    <dbReference type="Gramene" id="ABO97710">
        <property type="protein sequence ID" value="ABO97710"/>
        <property type="gene ID" value="OSTLU_33202"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33202"/>
    <dbReference type="eggNOG" id="KOG2936">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093992_0_0_1"/>
    <dbReference type="OMA" id="IEGEREC"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF22">
        <property type="entry name" value="LD43819P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="3">
        <location>
            <begin position="70"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="227" mass="25344" checksum="307BD689F96445A9" modified="2007-05-15" version="1">MSDDDDDARARRRDGDGKGELSYHYWHGRNAGEAPAATAKRITSEEAAALTRQVSSTQISAWNAAGTWEERGHTDWARARLETLVVERGKFDLDGAFAGVVARVVGVKKCEGDASVVMIRGKPRHGFDFETTLEWRASFAEEDGEDGEDEDGDEAAVEVQGTIHIPEFSRDCAEDEECAFEIKVENRKKEHREREDACYAALKKSCEEFIVGVLRQIDDELCERASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1U3</accession>
    <name>A4S1U3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_42709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419426.1">
        <property type="nucleotide sequence ID" value="XM_001419389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1U3"/>
    <dbReference type="STRING" id="436017.A4S1U3"/>
    <dbReference type="GeneID" id="5003124"/>
    <dbReference type="Gramene" id="ABO97719">
        <property type="protein sequence ID" value="ABO97719"/>
        <property type="gene ID" value="OSTLU_42709"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42709"/>
    <dbReference type="eggNOG" id="KOG3489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141397_1_1_1"/>
    <dbReference type="OMA" id="NEICWDK"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="77" mass="8512" checksum="8275D0EE03737564" modified="2007-05-15" version="1">MQANDAHMQQFLEEEKRKAVFNEVVAKLTETCFEKCVTYAPGAKFSSSESSCLTNCALRYLESGQVVLGRLQNMGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="112" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1U9</accession>
    <name>A4S1U9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_16561</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419430.1">
        <property type="nucleotide sequence ID" value="XM_001419393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1U9"/>
    <dbReference type="STRING" id="436017.A4S1U9"/>
    <dbReference type="GeneID" id="5003126"/>
    <dbReference type="Gramene" id="ABO97723">
        <property type="protein sequence ID" value="ABO97723"/>
        <property type="gene ID" value="OSTLU_16561"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16561"/>
    <dbReference type="eggNOG" id="KOG2411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014330_3_2_1"/>
    <dbReference type="OMA" id="LCGWVDR"/>
    <dbReference type="OrthoDB" id="439710at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00777">
        <property type="entry name" value="AspRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04317">
        <property type="entry name" value="EcAspRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="entry name" value="GAD-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047089">
        <property type="entry name" value="Asp-tRNA-ligase_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047090">
        <property type="entry name" value="AspRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001750">
        <property type="entry name" value="PRK00476.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="GAD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="8">
        <location>
            <begin position="140"/>
            <end position="587"/>
        </location>
    </feature>
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        <location>
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            <end position="22"/>
        </location>
    </feature>
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        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="623" mass="68151" checksum="5ADCB3EE74997ACD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S241</accession>
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        <recommendedName>
            <fullName evidence="6">CBM20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16632</name>
        <name evidence="4" type="ORF">OSTLU_19280</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419643.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422862.1">
        <property type="nucleotide sequence ID" value="XM_001422825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S241"/>
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    <dbReference type="GeneID" id="5007011"/>
    <dbReference type="Gramene" id="ABO97973">
        <property type="protein sequence ID" value="ABO97973"/>
        <property type="gene ID" value="OSTLU_16632"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01221">
        <property type="protein sequence ID" value="ABP01221"/>
        <property type="gene ID" value="OSTLU_19280"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16632"/>
    <dbReference type="KEGG" id="olu:OSTLU_19280"/>
    <dbReference type="HOGENOM" id="CLU_837812_0_0_1"/>
    <dbReference type="OMA" id="RWESPQA"/>
    <dbReference type="OrthoDB" id="500551at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007635046" description="CBM20 domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="181"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36183" checksum="8BFB27A0863C0FA7" modified="2007-05-15" version="1">MARAKKRARTIARAALVVSTALAIEGARATTFTADGRSCKWPLELAEDVFVNECVPYGRDGALWCVAEEDGKWGVCADLDFDASARGKVSMEAAARAATTLAREEELTYEARRQAMEVLESTSTLMLKALARESIEIEGKIVENPVVEFLAKRQRERPDNFNAVNDPTTSTPAPASTTSPPLQRPPPSPPPPSPPPLSPPPPNQPRCVARTDIRWESPQADGSSEFGMDIYIVLASGESISGGWKILFKFARDGVVLYSSSAYGADARTMYAPEDGRVFELRDRGYDAYIALYSTKRIGFNVRTRSAQSLRLSTLAVNGEDCEIVSESSIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S242</accession>
    <name>A4S242_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RPA-interacting protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_33318</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001419433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S242"/>
    <dbReference type="GeneID" id="5003713"/>
    <dbReference type="Gramene" id="ABO97763">
        <property type="protein sequence ID" value="ABO97763"/>
        <property type="gene ID" value="OSTLU_33318"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33318"/>
    <dbReference type="HOGENOM" id="CLU_1095788_0_0_1"/>
    <dbReference type="OMA" id="EAFERWK"/>
    <dbReference type="OrthoDB" id="435311at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028156">
        <property type="entry name" value="RIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028159">
        <property type="entry name" value="RPA_interact_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31742:SF1">
        <property type="entry name" value="RPA-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31742">
        <property type="entry name" value="RPA-INTERACTING PROTEIN RPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14768">
        <property type="entry name" value="RPA_interact_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RPA-interacting protein C-terminal" evidence="5">
        <location>
            <begin position="168"/>
            <end position="251"/>
        </location>
    </feature>
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        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="254" mass="28591" checksum="38955FC2BBB0E517" modified="2007-05-15" version="1">MRADESLESACVRVVLGLVGKRARTRGGADEKASASGTASSFDAARCREIVLEQHAKRRKVRGGRVGSVRGVRDADVDDFDEDDEDEDDYARLTEAEVERVLLAMQDAMERELANEERLMSERAEVEYREDEEEQERLTRAIEAFERWKFPEAEDVGENAESSGEDVLCPVCATRRVLYNRHVLFCACGDFRIARADENVGLTYLKRRLAETFEAHVSRGCGNAGGLRFSVRDEYGLDACVAKCERCSFLEIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S255</accession>
    <name>A4S255_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S255"/>
    <dbReference type="GeneID" id="5003721"/>
    <dbReference type="Gramene" id="ABO97768">
        <property type="protein sequence ID" value="ABO97768"/>
        <property type="gene ID" value="OSTLU_33330"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33330"/>
    <dbReference type="HOGENOM" id="CLU_326641_0_0_1"/>
    <dbReference type="OMA" id="DDQTWVR"/>
    <dbReference type="OrthoDB" id="10531048at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="882" mass="96413" checksum="EF4B3A3FBB55626A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S271</accession>
    <name>A4S271_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
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                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Jabbari K."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
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            <dbReference type="PubMed" id="17460045"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">CCE9901</strain>
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</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Salamov A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
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        <reaction evidence="9 12">
            <text>S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine</text>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.13.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="11 12">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <dbReference type="EC" id="3.13.2.1" evidence="8 12"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419579.1">
        <property type="nucleotide sequence ID" value="XM_001419542.1"/>
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    <dbReference type="AlphaFoldDB" id="A4S2R4"/>
    <dbReference type="STRING" id="436017.A4S2R4"/>
    <dbReference type="GeneID" id="5003785"/>
    <dbReference type="Gramene" id="ABO97872">
        <property type="protein sequence ID" value="ABO97872"/>
        <property type="gene ID" value="OSTLU_34856"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34856"/>
    <dbReference type="eggNOG" id="KOG1370">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025194_2_1_1"/>
    <dbReference type="OMA" id="YIGVTVE"/>
    <dbReference type="OrthoDB" id="10007170at2759"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033353">
        <property type="term" value="P:S-adenosylmethionine cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000004">
        <property type="entry name" value="Adenosylhomocysteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004005">
        <property type="entry name" value="PRK05476.2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420:SF0">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 12" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S-adenosyl-L-homocysteine hydrolase NAD binding" evidence="14">
        <location>
            <begin position="238"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="204"/>
            <end position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="269"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="346"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034527"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="482" mass="52707" checksum="D9DAAA6FE829FAC7" modified="2007-05-15" version="1">MCVVETSTAGREYKVRDMAQADFGRMEIELAQVEMPGLMSCIAEFGPAQPLAGANISGSLHMTIQTAVLIETLVALGANVRWCSCNIFSTQDHAAAAVARDSAAVFAWKGETLEEYWWCTDQMLNWGEGSLDIIVDDGGDATLLIHEGYKAELEFAKSGAIPDPASTDNAEMKCVLKIIAENLKTNPKRWQKIVSTCVGVSEETTTGVKRLYEMQKAGELLFPAINVNDSVTKCKFDNLYGCRHSLPDGIMRATDVMIASKTCWVAGYGDVGKGSAAALKAAGARVIVSEIDPICALQAAMEGYQVAPIEDVVDQVDIFITTTGNKDIIMVQHMEKMKNNAIVGNIGHFDNEIDMAGLESYPGIKRQNIKPQCDRFEFPDGHGIIMLAEGRLLNLGCATGHPSFVMSCSFTNQAIAQLELWNERKSGKYEKKVYVLPKHLDEKVAMLHLAKIGVKLTKLSTDQAQYINVPVEGPYKPAAYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2T3</accession>
    <name>A4S2T3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2T3"/>
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    <dbReference type="Gramene" id="ABO98094">
        <property type="protein sequence ID" value="ABO98094"/>
        <property type="gene ID" value="OSTLU_33559"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33559"/>
    <dbReference type="HOGENOM" id="CLU_2926820_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="61" mass="6876" checksum="348D3610A2A79F1B" modified="2007-05-15" version="1">MAMLAKTANEHFKARYGVDAFAFASRCVRRVRDDLREAFGGRGRTRGKGKFRGTGRRVGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S353</accession>
    <name>A4S353_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_34630</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419654.1">
        <property type="nucleotide sequence ID" value="XM_001419617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S353"/>
    <dbReference type="STRING" id="436017.A4S353"/>
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        <property type="gene ID" value="OSTLU_34630"/>
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    </dbReference>
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        <property type="component" value="Chromosome 9"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="158" mass="17615" checksum="381CF0CAFF822942" modified="2007-05-15" version="1" fragment="single">MSIDDFRIIKLISGGAYGRVFLAQKRATGDLFAVKALRKRDLVYKNMMDQVVAERDALIAAANPFTIKLYYSFTSARHVYLVTEYANGGDLYSLLTQLGRLSEEHARQYCAEIALALEYVHSKGITHRDLKPGNCLIASDGHIKLADFGLSRIDRDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S373</accession>
    <name>A4S373_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DDT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_16926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ABO98161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S373"/>
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    <dbReference type="Gramene" id="ABO98161">
        <property type="protein sequence ID" value="ABO98161"/>
        <property type="gene ID" value="OSTLU_16926"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16926"/>
    <dbReference type="HOGENOM" id="CLU_347305_0_0_1"/>
    <dbReference type="OMA" id="ELHVHAW"/>
    <dbReference type="OrthoDB" id="10499243at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022702">
        <property type="entry name" value="Cytosine_MeTrfase1_RFD"/>
    </dbReference>
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        <property type="entry name" value="DDT_dom"/>
    </dbReference>
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        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="507"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="813" mass="92231" checksum="77E0FC9D6FFF0287" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3M0</accession>
    <name>A4S3M0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="16">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_26100</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="16"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419944.1">
        <property type="nucleotide sequence ID" value="XM_001419907.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S3M0"/>
    <dbReference type="GeneID" id="5003983"/>
    <dbReference type="Gramene" id="ABO98237">
        <property type="protein sequence ID" value="ABO98237"/>
        <property type="gene ID" value="OSTLU_26100"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26100"/>
    <dbReference type="eggNOG" id="KOG0260">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000487_1_1_1"/>
    <dbReference type="OMA" id="QAFPIPH"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_Rpb1_1"/>
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        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
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        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
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        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
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        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
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        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05001">
        <property type="entry name" value="RNA_pol_Rpb1_R"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 16" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="13 16" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="18">
        <location>
            <begin position="219"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1459"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1528"/>
            <end position="1646"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1528"/>
            <end position="1636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO98237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1646" mass="183368" checksum="8FBEFCBCE4363E1F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3P6</accession>
    <name>A4S3P6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420094.1"/>
    </dbReference>
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    <dbReference type="Gramene" id="ABO98424">
        <property type="protein sequence ID" value="ABO98424"/>
        <property type="gene ID" value="OSTLU_93339"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93339"/>
    <dbReference type="HOGENOM" id="CLU_559469_0_0_1"/>
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        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="488" mass="53096" checksum="98D668D1C336771A" modified="2007-05-15" version="1">MPRARVDDARVATATATATATATATATATATRATGVALARAARPDDDDDDGLFDGLLDDDDDDDDDDDGGEDGDGVEETVESDDDDGSATTRRDDDDDADEDADEDAHEDAPEAGDEGTSGEDEGASTTTLDDLVRLGGVEARALMRDLFVEASKFGLDLDDEDEDEDEDEDEDVDIEGVLGQALGMDDEASAELLAVEYVEEEDDSEDERAIEQRKKLLLGLGVDIDAEPTPAVVEDATEDVVTETTTETTTETTTTPKPVLREVQPNVASSANREAHATKSRDGRTLLSVIDANNVRWLSWDDMPERLRKHVASTAPDAVDARAIRVGGYWRAASMNNRQRRKSKSRNGFPLRQGQVEEEVKECNQRHVVTNIQCFNEHARYAVITVEASHTFYPGDYVTFERIGAQNAEHAREINSQHRVFAVPVPLDADVSALNWDNIWAESPLVLPRQSVFAVSFDTPGSACDAFPVSSAIVRRSANTRLPFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3P8</accession>
    <name>A4S3P8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_17060</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420132.1">
        <property type="nucleotide sequence ID" value="XM_001420095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3P8"/>
    <dbReference type="STRING" id="436017.A4S3P8"/>
    <dbReference type="GeneID" id="5003996"/>
    <dbReference type="Gramene" id="ABO98425">
        <property type="protein sequence ID" value="ABO98425"/>
        <property type="gene ID" value="OSTLU_17060"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17060"/>
    <dbReference type="eggNOG" id="KOG0749">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_12_0_1"/>
    <dbReference type="OMA" id="KFQELAW"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000061">
        <property type="entry name" value="ADP/ATP transporter on adenylate translocase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="113"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="208"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO98425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="299" mass="32349" checksum="781408CB964E452D" modified="2007-05-15" version="1">MPISVIPYRSSKLRPGGVSGSIAKTATAPIERVKLLIQTQDANPRIMSGEVPRYTGIVNCFTRVSAEQGFGSFWRGNTANIVRYFPTQAFNFAFKDTIKGLFPSYSPKDAFWPFFAVNMASGGLAGAGSLLIVYPLDFARTRLAADVGKANDREFTGLVDCLSKIARRSGPMALYQGFGVSVQGIIVYRGSYFGLYDTGKGALLTKDSSFIFKFIVAQVATNAAGVLSYPFDTVRRRLMMNSGAGKKLYSGTVDAFVKIYAQEGMGAFFKGAFSNVLRGVGGALVLVMYDEIKAVINPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3X7</accession>
    <name>A4S3X7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420170.1">
        <property type="nucleotide sequence ID" value="XM_001420133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3X7"/>
    <dbReference type="GeneID" id="5004037"/>
    <dbReference type="Gramene" id="ABO98463">
        <property type="protein sequence ID" value="ABO98463"/>
        <property type="gene ID" value="OSTLU_17117"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17117"/>
    <dbReference type="eggNOG" id="ENOG502SV47">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_329110_0_0_1"/>
    <dbReference type="OMA" id="HTHELHD"/>
    <dbReference type="OrthoDB" id="188741at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037386">
        <property type="entry name" value="CCDC40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275:SF8">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="411"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="520"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="608"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="864" mass="98582" checksum="8BB0F39394093E6A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Z6</accession>
    <name>A4S3Z6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_88475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420179.1">
        <property type="nucleotide sequence ID" value="XM_001420142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Z6"/>
    <dbReference type="STRING" id="436017.A4S3Z6"/>
    <dbReference type="GeneID" id="5004098"/>
    <dbReference type="Gramene" id="ABO98472">
        <property type="protein sequence ID" value="ABO98472"/>
        <property type="gene ID" value="OSTLU_88475"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88475"/>
    <dbReference type="eggNOG" id="ENOG502QQ60">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_593671_0_0_1"/>
    <dbReference type="OMA" id="QWAATHP"/>
    <dbReference type="OrthoDB" id="496940at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="461" mass="49945" checksum="FC676CB6303C8CF9" modified="2007-05-15" version="1">MPPPPSGGPQKYRGEALPEWADGPTALAASMDVPGMPGVRAAPTPMMPSGPMPTNQPRQFQQRERQQGRRPREQRPRGRPHYNGLYMANDEIEGILRIQWSATHPHDRPAYEHDYFYQSWLRRNNPSKLKEPFCPESLRELASHEKEARGPVTFVPGLAGLGKVPFGNIRSPKPLLDVSSSNAPKTDGDDDAGEEGTQRRLEQEPLLAARIMIEDSMCLLLDVDDIDRQLEEGRPSESDEDLKKRRMFLLDGLVSTLRLPSVPVLAVGGAEHDGVFQRIVTLPKGRTLLASALPRFPLGSAAAATLVWAILRNVGMLLGGKNATNNPSAEALFRAAADSVQLMNAVAVEGTLGAVATGMNIADAKQQLAPLVSRNSTTGALVAALSAALERAHLLEISPSTHKAFGAAFGIVFSIFDRHATNAAQRGGSDSALPRDLLRALMHHCNDAQKQRLKSHISALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4G4</accession>
    <name>A4S4G4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_26403</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sterol desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420263.1">
        <property type="nucleotide sequence ID" value="XM_001420226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4G4"/>
    <dbReference type="STRING" id="436017.A4S4G4"/>
    <dbReference type="GeneID" id="5004331"/>
    <dbReference type="Gramene" id="ABO98556">
        <property type="protein sequence ID" value="ABO98556"/>
        <property type="gene ID" value="OSTLU_26403"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26403"/>
    <dbReference type="eggNOG" id="ENOG502QQ3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017842_2_0_1"/>
    <dbReference type="OMA" id="CEMTMPR"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043447">
        <property type="term" value="P:alkane biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009611">
        <property type="term" value="P:response to wounding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010025">
        <property type="term" value="P:wax biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021940">
        <property type="entry name" value="CER1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12076">
        <property type="entry name" value="CER1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="7">
        <location>
            <begin position="129"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Very-long-chain aldehyde decarbonylase CER1-like C-terminal" evidence="8">
        <location>
            <begin position="450"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="621" mass="70636" checksum="23AEEE2FC23F663D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4T5</accession>
    <name>A4S4T5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MAT1 centre domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420492.1">
        <property type="nucleotide sequence ID" value="XM_001420455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4T5"/>
    <dbReference type="STRING" id="436017.A4S4T5"/>
    <dbReference type="GeneID" id="5004567"/>
    <dbReference type="Gramene" id="ABO98785">
        <property type="protein sequence ID" value="ABO98785"/>
        <property type="gene ID" value="OSTLU_26522"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26522"/>
    <dbReference type="eggNOG" id="KOG3800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124148_0_0_1"/>
    <dbReference type="OMA" id="DMLGGEY"/>
    <dbReference type="OrthoDB" id="5963at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015877">
        <property type="entry name" value="MAT1_centre"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683:SF13">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06391">
        <property type="entry name" value="MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAT1 centre" evidence="1">
        <location>
            <begin position="9"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="168" mass="18356" checksum="70F0ACF9F12ED285" modified="2007-05-15" version="1">MDLLARATRARQRVLAVFNARQSDFESLRAWNDHLERVEELIFNLTEGVDASATESAIAEHKRRNASEIARYAARARDEGRAAMGETAEAMDAGEGYAPETANGDVVAQPVPTSAVRRGLEKTSLDYDENTEEGRKARAAAIARACGFDGRAVAKARCLREAFATIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4X2</accession>
    <name>A4S4X2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420343.1">
        <property type="nucleotide sequence ID" value="XM_001420306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4X2"/>
    <dbReference type="GeneID" id="5004396"/>
    <dbReference type="Gramene" id="ABO98636">
        <property type="protein sequence ID" value="ABO98636"/>
        <property type="gene ID" value="OSTLU_26560"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26560"/>
    <dbReference type="eggNOG" id="ENOG502QQB5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088053_0_0_1"/>
    <dbReference type="OMA" id="ETHGIAR"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE YKTD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619:SF2">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="219" mass="24203" checksum="98E4B18BF2F262D2" modified="2007-05-15" version="1">MDVLAFRRLSAMMNTFEKNVETHGIARQVVVITAGADTRAFRLPFPSGTAIFECADGTVHTKAAAVMKKVGAKPSKGCSHRRVPVDATATDAAYGDLEERLERAGYRPDVRSLWLVQDVHAWDHSRLSNFITESADLMTTGSELIIDASALTSTDDIIRREFASNGVMPEVVRIPADEGREPIRLVLGCAQRVSLKESEYYREQLRAAEDEADEDGFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5G3</accession>
    <name>A4S5G3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HTA3503</name>
        <name evidence="13" type="ORF">OSTLU_13104</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420769.1">
        <property type="nucleotide sequence ID" value="XM_001420732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5G3"/>
    <dbReference type="STRING" id="436017.A4S5G3"/>
    <dbReference type="GeneID" id="5004839"/>
    <dbReference type="Gramene" id="ABO99062">
        <property type="protein sequence ID" value="ABO99062"/>
        <property type="gene ID" value="OSTLU_13104"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13104"/>
    <dbReference type="eggNOG" id="KOG1756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062828_3_3_1"/>
    <dbReference type="OMA" id="THHEYAK"/>
    <dbReference type="OrthoDB" id="496320at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000009">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="11">
        <location>
            <begin position="8"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="12">
        <location>
            <begin position="90"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="12809" checksum="724F6056B3E1C5F4" modified="2007-05-15" version="1">MSGRGKGKSGKKATSRSAKAGLQFPVGRVARYLKAGKYATRVGAGAPVYLAAVLEYLCAEVLELAGNASRDNKKSRIVPRHIQLAIRNDEELSKLLGTVTIAAGGVLPNIHSVLLPKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5J9</accession>
    <name>A4S5J9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420623.1">
        <property type="nucleotide sequence ID" value="XM_001420586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5J9"/>
    <dbReference type="GeneID" id="5004622"/>
    <dbReference type="Gramene" id="ABO98916">
        <property type="protein sequence ID" value="ABO98916"/>
        <property type="gene ID" value="OSTLU_26792"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26792"/>
    <dbReference type="eggNOG" id="ENOG502SG91">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2444828_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="90" mass="9966" checksum="AFAEFB77580071D6" modified="2007-05-15" version="1">MRPMPEGAAPVVDEDMPKQDEEELRRRRAQALKSWLEDELGTEKTALMAVLAKHRVQIPGGGDEAKALLEELLEWKAEGVVNARSTDAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S689</accession>
    <name>A4S689_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_7826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420903.1">
        <property type="nucleotide sequence ID" value="XM_001420866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S689"/>
    <dbReference type="STRING" id="436017.A4S689"/>
    <dbReference type="GeneID" id="5005080"/>
    <dbReference type="Gramene" id="ABO99196">
        <property type="protein sequence ID" value="ABO99196"/>
        <property type="gene ID" value="OSTLU_7826"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7826"/>
    <dbReference type="eggNOG" id="KOG0884">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_0_1"/>
    <dbReference type="OMA" id="ITIHSTY"/>
    <dbReference type="OrthoDB" id="408413at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00317">
        <property type="entry name" value="cyclophilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044233">
        <property type="entry name" value="CYP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47511">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47511:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="17578" checksum="D2E0425FA093496A" modified="2007-05-15" version="1" fragment="single">LVMQTTLGDVTLALYDHDDAARATAAHVLEAFELGLYDTNHFFRVDAGFVAQIADCAGGRRAAMSERQRELATRTVRGEFDASVKHARGKLSMARWSDPDSATSSFSVMLGTAPHLDGEYAVFGEMVEGEETLRKIEAVETTKSGIFVMPKERIEILSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6B8</accession>
    <name>A4S6B8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27062</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421067.1">
        <property type="nucleotide sequence ID" value="XM_001421030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6B8"/>
    <dbReference type="STRING" id="436017.A4S6B8"/>
    <dbReference type="GeneID" id="5005025"/>
    <dbReference type="Gramene" id="ABO99360">
        <property type="protein sequence ID" value="ABO99360"/>
        <property type="gene ID" value="OSTLU_27062"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27062"/>
    <dbReference type="eggNOG" id="ENOG502RZSC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102343_0_0_1"/>
    <dbReference type="OMA" id="KFCANLM"/>
    <dbReference type="OrthoDB" id="513226at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.210">
        <property type="entry name" value="Chaperonin-like RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038052">
        <property type="entry name" value="Chaperonin_RbcX_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003435">
        <property type="entry name" value="Chaperonin_RcbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791">
        <property type="entry name" value="CHAPERONIN-LIKE RBCX PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791:SF1">
        <property type="entry name" value="RUBISCO CHAPERONE RBCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02341">
        <property type="entry name" value="RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158615">
        <property type="entry name" value="RbcX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="144" mass="15964" checksum="4D00412F273C380C" modified="2007-05-15" version="1">MFVPAGAFGGVSPERRASELMNAMLTYVSAWIVISQLENVAPRRSVAGEDAGEDGEGEARRVTTSHEFLLDYLEANPVRDGEQWLIALTRVNPTLAERIMAVRRAYAEEDFEWHNVAKLTSESIAAGNERAMREWLKSAVPQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6R0</accession>
    <name>A4S6R0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CDC20/Fizzy WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_13210</name>
        <name evidence="9" type="ORF">OSTLU_13512</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421135.1">
        <property type="nucleotide sequence ID" value="XM_001421098.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422820.1">
        <property type="nucleotide sequence ID" value="XM_001422783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6R0"/>
    <dbReference type="STRING" id="436017.A4S6R0"/>
    <dbReference type="GeneID" id="5004991"/>
    <dbReference type="GeneID" id="5006878"/>
    <dbReference type="Gramene" id="ABO99428">
        <property type="protein sequence ID" value="ABO99428"/>
        <property type="gene ID" value="OSTLU_13210"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01179">
        <property type="protein sequence ID" value="ABP01179"/>
        <property type="gene ID" value="OSTLU_13512"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13210"/>
    <dbReference type="KEGG" id="olu:OSTLU_13512"/>
    <dbReference type="eggNOG" id="KOG0305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014831_1_1_1"/>
    <dbReference type="OMA" id="RDRTICM"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="3"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="172"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="230" mass="25097" checksum="0C3FBC222A59FF46" modified="2007-05-15" version="1">MLGHRSRAGTLAWNSHTLSSGSRDRAILNRDIRSPSDYSSKLLGHKSEVCGLKWSYDDQQLASGGNDNQLFVWNSHSTSPILRCSEHTAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTVTNTPLQCVDTGSQVCNLVWSKNVNEIVSTHGYSQNQIVVWRYPSMSKLTTLTGHTLRVLFLAISPDGQTIVTGAGDETLRFWNVFPGMKSPVSGAGDNTVSTLARTSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6W1</accession>
    <name>A4S6W1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ClpYQ (HslUV)-type protease, ATP-dependent subunit ClpY (HslU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ClpY_13</name>
        <name evidence="10" type="synonym">ClpY_21</name>
        <name evidence="9" type="ORF">OSTLU_41786</name>
        <name evidence="10" type="ORF">OSTLU_89815</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421162.1">
        <property type="nucleotide sequence ID" value="XM_001421125.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422793.1">
        <property type="nucleotide sequence ID" value="XM_001422756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6W1"/>
    <dbReference type="STRING" id="436017.A4S6W1"/>
    <dbReference type="GeneID" id="5005220"/>
    <dbReference type="GeneID" id="5006941"/>
    <dbReference type="Gramene" id="ABO99455">
        <property type="protein sequence ID" value="ABO99455"/>
        <property type="gene ID" value="OSTLU_41786"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01152">
        <property type="protein sequence ID" value="ABP01152"/>
        <property type="gene ID" value="OSTLU_89815"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41786"/>
    <dbReference type="KEGG" id="olu:OSTLU_89815"/>
    <dbReference type="eggNOG" id="KOG0745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033123_0_0_1"/>
    <dbReference type="OMA" id="YGMIKTD"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ATP-dependent protease ATPase subunit HslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003544">
        <property type="entry name" value="PRK05201.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE ATPASE SUBUNIT HSLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="146"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="8">
        <location>
            <begin position="424"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP01152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="542" mass="59842" checksum="DD1408DFC29864C3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S762</accession>
    <name>A4S762_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27364</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO99510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S762"/>
    <dbReference type="STRING" id="436017.A4S762"/>
    <dbReference type="GeneID" id="5005403"/>
    <dbReference type="Gramene" id="ABO99510">
        <property type="protein sequence ID" value="ABO99510"/>
        <property type="gene ID" value="OSTLU_27364"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27364"/>
    <dbReference type="eggNOG" id="KOG0152">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_502888_0_0_1"/>
    <dbReference type="OMA" id="DDWSRAM"/>
    <dbReference type="OrthoDB" id="498409at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="5"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="4">
        <location>
            <begin position="378"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="508"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="63012" checksum="F9D790B6894DF793" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8R8</accession>
    <name>A4S8R8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exostosin GT47 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_18436</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421936.1">
        <property type="nucleotide sequence ID" value="XM_001421899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8R8"/>
    <dbReference type="CAZy" id="GT47">
        <property type="family name" value="Glycosyltransferase Family 47"/>
    </dbReference>
    <dbReference type="GeneID" id="5005866"/>
    <dbReference type="Gramene" id="ABP00230">
        <property type="protein sequence ID" value="ABP00230"/>
        <property type="gene ID" value="OSTLU_18436"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18436"/>
    <dbReference type="eggNOG" id="KOG1021">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_557120_0_0_1"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF281">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671932" description="Exostosin GT47 domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Exostosin GT47" evidence="5">
        <location>
            <begin position="144"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="490" mass="55489" checksum="A8A41A35A41BAD4C" modified="2007-05-15" version="1">MRSLRVVLMALFLFSAITSLAMMSVGVRSVHVREFRSASEGQLLDAWSLMRHLVGRRGGGGYRRDAATRFDEYGFPTFRAMCSDGGVGDGKDFPLRRSSGYDGFTGLCASMESLPRRLCVKSFRQPTRTRVRNALIRRVAMNWNRAFDVEDFLNRNFQNGPFSSCASSVDDVNDAYLLPLNPYFDRVMDKLRHFSEKGRSAMARGVKHAIDYASAEDPNAWVRSGESCSRFSVITHGSSTMSLLRHKDVILSTTFVVASSETISPSRPHTSQAPFHPDKDVSAINSLSFVIPLHAARRRAFANAERETLLMFRGAINSFPNRREIADFLLKNTRGQMYDLGPSCSTSKEYTAKMKNSRFCLYMRGTRVHSPRLIESMLFGCVPVILADDYELPLSWLVDWSAFSVMIPERDFQTIPDALERANSDWDAMHMRLQMVLPLFLYRRRPLVGDAFWATALGVERQLRRRRAECTKNVFANVSIPWNTVGADTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8T7</accession>
    <name>A4S8T7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FBP17-2</name>
        <name evidence="4" type="ORF">OSTLU_18447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421814.1">
        <property type="nucleotide sequence ID" value="XM_001421777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8T7"/>
    <dbReference type="STRING" id="436017.A4S8T7"/>
    <dbReference type="GeneID" id="5005977"/>
    <dbReference type="Gramene" id="ABP00108">
        <property type="protein sequence ID" value="ABP00108"/>
        <property type="gene ID" value="OSTLU_18447"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18447"/>
    <dbReference type="eggNOG" id="KOG0552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090476_1_0_1"/>
    <dbReference type="OMA" id="GICQGVE"/>
    <dbReference type="OrthoDB" id="498507at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053111">
        <property type="entry name" value="Chloro_FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47598">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP17-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47598:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP17-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673124" description="peptidylprolyl isomerase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="3">
        <location>
            <begin position="66"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="175" mass="19222" checksum="D45F8E2F2CEC1563" modified="2007-05-15" version="1">MTRRFGLKGGLAWLGALTFGVLSEQLKTRRETREAIENTEDVRREDLKTVELPSGVTYVEYTRGGGERVRKQYLCAAKLRARAVSAEEAEAYAYDTESAGREIVWSFGGKLGPPLCRGLEEGVAGMRQGGRRVVRVPARLAFGSDGADFPRGGKIDPDRDVEFDVTLTRVSVPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8V0</accession>
    <name>A4S8V0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421953.1">
        <property type="nucleotide sequence ID" value="XM_001421916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8V0"/>
    <dbReference type="STRING" id="436017.A4S8V0"/>
    <dbReference type="GeneID" id="5006113"/>
    <dbReference type="Gramene" id="ABP00247">
        <property type="protein sequence ID" value="ABP00247"/>
        <property type="gene ID" value="OSTLU_27977"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27977"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058290_0_0_1"/>
    <dbReference type="OMA" id="VFYCEIM"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="CDD" id="cd08774">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="3">
        <location>
            <begin position="6"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="254" mass="28282" checksum="4DFD32F7E33B9B24" modified="2007-05-15" version="1">MSLDARQRCVFEAKLAEQAERHDEQVKAMRALCALEGVDALTTDERNMLSVGYKNVIGARRGSWRILNSIEEKERGKGHEAQAEKVRGYRTRVEKELKDICADVLEVLDGRLLSKASGDGESVVFYLKMKADYYRYLAEVSSGDEREEASKNADEAYAEATTMANGKGSTDGLPPTHPVRLGLALNHSVFHYEIGNDSTKACELAKTAFEEAIADLDTLTDESYKDSTLIMQLLRDNLTLWTSDANDDDDDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S940</accession>
    <name>A4S940_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_13349</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421868.1">
        <property type="nucleotide sequence ID" value="XM_001421831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S940"/>
    <dbReference type="STRING" id="436017.A4S940"/>
    <dbReference type="GeneID" id="5005897"/>
    <dbReference type="Gramene" id="ABP00162">
        <property type="protein sequence ID" value="ABP00162"/>
        <property type="gene ID" value="OSTLU_13349"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13349"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_1"/>
    <dbReference type="OMA" id="DMPLAQY"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="1"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="341" mass="35768" checksum="660D52C9E2544E31" modified="2007-05-15" version="1">MTIDVERHAVGDDDVSFDLAYCGICHTDLHFAMNDLGNTRYPIVPGHELIGTVTEVGKNAASRGFAIGDVVGVGCIVDSCLACKYCASNEEQYCEAGMTMTYGGETKHGRAGPNGQITVGGYSTKHVVDSRFAIKIPKGVDDLAACAPLMCAGITLFDPIKAFGVREGMRVGVAGIGGLGQMGIKIAAALGAEVTAISRTNAKEAKAKAAGAKHFIASSDAEAMKNAAGSLDLILDTVSASHDSEPYAAMLDKKGTLCLLGLQTAPVAVNATQFVFNRIAVTGSLIGGIKNTQEMIDFCVEKKLYPEIKIIDAKEIPEALKNLNDGNDAGVRYVIDCKTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S945</accession>
    <name>A4S945_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_51690</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422000.1">
        <property type="nucleotide sequence ID" value="XM_001421963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S945"/>
    <dbReference type="STRING" id="436017.A4S945"/>
    <dbReference type="GeneID" id="5005900"/>
    <dbReference type="Gramene" id="ABP00294">
        <property type="protein sequence ID" value="ABP00294"/>
        <property type="gene ID" value="OSTLU_51690"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51690"/>
    <dbReference type="eggNOG" id="KOG2898">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031080_1_0_1"/>
    <dbReference type="OMA" id="ANHTTVM"/>
    <dbReference type="OrthoDB" id="10051137at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd07991">
        <property type="entry name" value="LPLAT_LPCAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045252">
        <property type="entry name" value="LPCAT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF2">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063">
        <property type="entry name" value="PHOSPHOLIPID ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="13">
        <location>
            <begin position="174"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABP00294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="380" mass="43505" checksum="05EA85FAA5F52B3B" modified="2007-05-15" version="1">MGARSLSFAPFDSFGDGELEREEVQRVTPGIELERRATASRTSTPEDAATLARLLDCSGILQDACAAMIDDSFNRCFQESAEANWNFNFYLLPLWWCGWVIRHFVLFPLRLGFILSASAAFALAFMFSHYCTPRRWGFERKCVELYAAAFVVSWTGVIKYHGPRPSRRGHMGGMVYVSNHTSMIDYLVMTQVSPFAVIQQKHKGWVGLLQRTAMNAIDCIEFNRTDIKDRNTVATRLKQHVAEKSRLPLLIFPEGTCVNNKYCVMFKRGAFDLGVDVVPVAIKYNNIFVDAFWNSRRQSFSRHLCTLMSSWAVVADVWYMEPQRKREDETSIEFAERVRGMICKRAGLKAVPWDGMLKYYRPSPRECEARRKAFLAGLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9B7</accession>
    <name>A4S9B7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plastid division regulator MinE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MinE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421906.1">
        <property type="nucleotide sequence ID" value="XM_001421869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9B7"/>
    <dbReference type="STRING" id="436017.A4S9B7"/>
    <dbReference type="GeneID" id="5006077"/>
    <dbReference type="Gramene" id="ABP00200">
        <property type="protein sequence ID" value="ABP00200"/>
        <property type="gene ID" value="OSTLU_28147"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28147"/>
    <dbReference type="eggNOG" id="ENOG502QVF0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1780550_0_0_1"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1070.10">
        <property type="entry name" value="Cell division topological specificity factor MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005527">
        <property type="entry name" value="MinE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036707">
        <property type="entry name" value="MinE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03776">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16747" checksum="E7C201224A10BE4C" modified="2007-05-15" version="1">MKMGRATRATTRTRAIANEAQTSEELNFWGKMRQAYRIFFPPSAEENARNEAKKRLRMILVADRCTMSESSMDEMKAKIMTVVGEFVDVDDSQEVDVSMNTDEELGTMYAVSIPVKRVKAEYDAENDAYMLGAQFVYDDENVWDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9C0</accession>
    <name>A4S9C0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422038.1">
        <property type="nucleotide sequence ID" value="XM_001422001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9C0"/>
    <dbReference type="GeneID" id="5005937"/>
    <dbReference type="Gramene" id="ABP00332">
        <property type="protein sequence ID" value="ABP00332"/>
        <property type="gene ID" value="OSTLU_13371"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13371"/>
    <dbReference type="eggNOG" id="KOG1454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_4_1"/>
    <dbReference type="OMA" id="HCIHHDA"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46438">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46438:SF12">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="50"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="323" mass="35359" checksum="B643979637D561CC" modified="2007-05-15" version="1">MTSTGTTTPATRAQRYGVDERYWRWRAPRTNETHAIRYTEAVGDGDGPAVVLVHGFGGNADHWRRNVNALAATGKRVYAIDLLGYGYSDKPNPMLREQNEIYCFETWGKQIEDFLDEVVGTPAYVACNSVGGVAGLQAAVDAPTKVRGVVLMNISLRGLHVSKQPAIIRPFVKALQRTLRETSVGKSFFGSVAKARTVKNILCEAYGDSAQVTDELVEAILSPGLREGAAEVFLDFISYSGGPLPEELLPRCDVPVRMFWGDKDPWENIDQGRKLYASYADKFIPLPGVGHCPQDEAPELVNRLLVECVDEWEAARAAAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9C9</accession>
    <name>A4S9C9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422043.1">
        <property type="nucleotide sequence ID" value="XM_001422006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9C9"/>
    <dbReference type="GeneID" id="5006083"/>
    <dbReference type="Gramene" id="ABP00337">
        <property type="protein sequence ID" value="ABP00337"/>
        <property type="gene ID" value="OSTLU_28159"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28159"/>
    <dbReference type="HOGENOM" id="CLU_053414_0_0_1"/>
    <dbReference type="OrthoDB" id="10340698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="1">
        <location>
            <begin position="74"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="355" mass="39632" checksum="0DFE00225EAB400D" modified="2007-05-15" version="1">MRAPAKADVINRISLRTRVPGLRSPGRGVPGLRTHVRETQRASDDARILILTKPFEWGMTYLQIQSVKRWAPALLPHVTVLTYDTETQRSCEAHRGVDCFYDADFARAYGQDPNDGVARDAMSWRKVHAALELLKARIPVVMLDSDTVFLSDPTEAWTSALEKYDVVVSSDVGNEFEAQGNMNTKLVIFPATTRSVSLCERWLEGESRLVSKVNYGEFPEQSYFNYVLVPTTAGEFHIHAMSTAESGNFITANAGDDGTFPGAHTVTASYCGDARDKEQFLQHVLETKHNAEAALGIGPDATTAIPLRSATDFDHDGVADLARFPHPDLRCDHVKRRLVDQRRYEVTSDRHIVWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9D5</accession>
    <name>A4S9D5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_9736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421916.1">
        <property type="nucleotide sequence ID" value="XM_001421879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9D5"/>
    <dbReference type="STRING" id="436017.A4S9D5"/>
    <dbReference type="GeneID" id="5005945"/>
    <dbReference type="Gramene" id="ABP00210">
        <property type="protein sequence ID" value="ABP00210"/>
        <property type="gene ID" value="OSTLU_9736"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9736"/>
    <dbReference type="eggNOG" id="KOG0712">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_18_2_1"/>
    <dbReference type="OrthoDB" id="498887at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="70" mass="7756" checksum="2B7ED8699678AEB8" modified="2007-05-15" version="1" fragment="single">YAILGVDSAATTSEITRAYRSIAIKHHPDRRRGRANPTGQDDGDEKFVEAQAAYEILKDDAKREFYDAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9T5</accession>
    <name>A4S9T5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP-dependent Zn protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422227.1">
        <property type="nucleotide sequence ID" value="XM_001422190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9T5"/>
    <dbReference type="STRING" id="436017.A4S9T5"/>
    <dbReference type="GeneID" id="5006181"/>
    <dbReference type="Gramene" id="ABP00544">
        <property type="protein sequence ID" value="ABP00544"/>
        <property type="gene ID" value="OSTLU_18697"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18697"/>
    <dbReference type="eggNOG" id="ENOG502QWEW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053953_3_0_1"/>
    <dbReference type="OMA" id="CTVWMAG"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33471">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33471:SF7">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="246" mass="26738" checksum="420BDF750B253E9F" modified="2007-05-15" version="1">MQRRNVFPNELKRLLKCAPEQIARPSDANDFNLIVTVTLSTSLLATVVGATLPGDWGAFGAYLIGGISLAVLAVGSTAPGLLRVATDRLARVNPEYRRRIARHEAGHFLVGYALGVPVGSYDLGIDQSHVNFMESKLERKIFQGAKLSESEMLPLAVVSMSGVAAEAMEFDEVMGQSADLYDLQRILNRVDPKLSDASQQELTRWAVFQAASILKTNKSAWDTLTEKMLDGASVVECLKTIESTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA39</accession>
    <name>A4SA39_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28418</name>
        <name evidence="1" type="ORF">OSTLU_28514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422312.1">
        <property type="nucleotide sequence ID" value="XM_001422275.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422313.1">
        <property type="nucleotide sequence ID" value="XM_001422276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA39"/>
    <dbReference type="GeneID" id="5006355"/>
    <dbReference type="GeneID" id="5006415"/>
    <dbReference type="Gramene" id="ABP00629">
        <property type="protein sequence ID" value="ABP00629"/>
        <property type="gene ID" value="OSTLU_28514"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP00630">
        <property type="protein sequence ID" value="ABP00630"/>
        <property type="gene ID" value="OSTLU_28418"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28418"/>
    <dbReference type="KEGG" id="olu:OSTLU_28514"/>
    <dbReference type="HOGENOM" id="CLU_1263361_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="219" mass="24658" checksum="20B4DEF8A58D4BA2" modified="2007-05-15" version="1">MQPEDAGEGVTVPSQVGDDALGIVPVDEYETVFSFPTVGKDSELCVTRCHGFWLTFYVDDTRSVSGQGPRANKTKYARSMRAFKVRASKRDPPKFFVSTPPAGLFSHRDIVWQCDVQWPYEKSASNWLHAVIPAERLLDFRRGVQCDAATEFRVYSRYKKGRGTNSVGSLYTNITIWHCFCGPEDHSVDAKEKFAKLCSGKAKRISRKVGCQCRLGFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA56</accession>
    <name>A4SA56_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422289.1">
        <property type="nucleotide sequence ID" value="XM_001422252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA56"/>
    <dbReference type="GeneID" id="5006359"/>
    <dbReference type="Gramene" id="ABP00606">
        <property type="protein sequence ID" value="ABP00606"/>
        <property type="gene ID" value="OSTLU_18797"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18797"/>
    <dbReference type="HOGENOM" id="CLU_861638_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673149" evidence="2">
        <location>
            <begin position="34"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="323" mass="36010" checksum="26CAA3F812D30D2B" modified="2007-05-15" version="1">MDHGCQPPRTFQARHSCRLWFVFTVSVACVVVGSRGASYGTYENDGGVTRERRADRARRPAIESRSSLSEVTRETYERARTVFEEFLNERSAQCGRAFTETRTHFGAPVETPPYPGGPPPGTGAVLTEMVRAAAAAWHRNMSYVMRGKWALVSDSDCAEAEFQGFACMFPGLSRSCRALEGENPMLNLQDAQDFWRHWSKNLSVDAIFLFGLAADALTDVRRASVKVKSFLEHDLSSALAGSESEGIAVGIHFRNRGDIRLDGRLRIPLERYVESRWTGCSRAQRAFSRSFVRIPNDQAFVGTSDRHKPVADDDDGDGGWFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="106" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAE9</accession>
    <name>A4SAE9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">p-ATPase family transporter: proton</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_42210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422424.1">
        <property type="nucleotide sequence ID" value="XM_001422387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAE9"/>
    <dbReference type="STRING" id="436017.A4SAE9"/>
    <dbReference type="GeneID" id="5006432"/>
    <dbReference type="Gramene" id="ABP00741">
        <property type="protein sequence ID" value="ABP00741"/>
        <property type="gene ID" value="OSTLU_42210"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42210"/>
    <dbReference type="eggNOG" id="KOG0205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_6_4_1"/>
    <dbReference type="OMA" id="VMFARVR"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="563"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="597"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="632"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="7">
        <location>
            <begin position="31"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="723" mass="77543" checksum="2B22CDAA93167761" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAF3</accession>
    <name>A4SAF3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_42270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLOC1S2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAF3"/>
    <dbReference type="GeneID" id="5006434"/>
    <dbReference type="Gramene" id="ABP00693">
        <property type="protein sequence ID" value="ABP00693"/>
        <property type="gene ID" value="OSTLU_42270"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42270"/>
    <dbReference type="HOGENOM" id="CLU_2201430_0_0_1"/>
    <dbReference type="OrthoDB" id="444265at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019269">
        <property type="entry name" value="BLOC1_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47882">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47882:SF1">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10046">
        <property type="entry name" value="BLOC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="108" mass="11585" checksum="3DC1BFC67A35AE86" modified="2007-05-15" version="1">MAARAFTKIADTVNAELSLAASEVRFLQNANETAAREYDAVGESIADLHVFIGALKAKDEAMKPKLDAILAIEGEVDALETLARAVDKRVSALELRLKSIKSKRASAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAJ2</accession>
    <name>A4SAJ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_94028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422398.1">
        <property type="nucleotide sequence ID" value="XM_001422361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAJ2"/>
    <dbReference type="GeneID" id="5006456"/>
    <dbReference type="Gramene" id="ABP00715">
        <property type="protein sequence ID" value="ABP00715"/>
        <property type="gene ID" value="OSTLU_94028"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94028"/>
    <dbReference type="HOGENOM" id="CLU_736898_0_0_1"/>
    <dbReference type="OMA" id="ITAECIC"/>
    <dbReference type="OrthoDB" id="512027at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="230"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="376" mass="39051" checksum="A0D6CB2F9D9B6915" modified="2007-05-15" version="1" fragment="single">VVTSPWRSRPTISYSYGTCDRTPRPPTQPQTDAEIFVFSRARGDNSEGQLGACGCGGCVAYDAADTGVCTVNSTAACPCNCGGQGTCVYTPASAANNFIATNEGKCVTYGTGAEAVAKCNCAKGALNPTLNPPRMVGQISLMDEPMVSDLSYEKQFTTVTYASAGGGAMFAISESNCKDDADGVVCSGRGQCLADGSCNCNDGSGGPTCENVCPLATDEDEALFSRYGLDENIAGEKCAGHGTCDPITAECICDPGFFGPRCTYICRRDANLKVCSGNGTCVYNPETSSSPYCECDRFQNPGECAQRGLQLYPQGWCSFHGGEATGGFASCFVAGVCGDCESPAAGRFDSPLVLVLLFAAVVVFVFGDDSHRDGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAY7</accession>
    <name>A4SAY7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">CCE9901</strain>
        </source>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP00839.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB51</accession>
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        </recommendedName>
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        <name evidence="6" type="ORF">OSTLU_29489</name>
    </gene>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
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        <property type="gene ID" value="OSTLU_29489"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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            <begin position="37"/>
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        </location>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP01033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="230" mass="26384" checksum="8CAC45CE87CB6947" modified="2007-05-15" version="1">MRTIANERDALAATEARAARAILDHRLGIIDDDQRARRAALVAKQFAEREALAIDEELDEPFDLHELYAFLMMPADKVAKAFGMPSGSFRLQCRKAGVTRWPHRHAQAVVGCHEYIAQLMQHTLAQFEYSIDDMEMCDVNYYSHRARSAFLRMDYAMTDLLEDLDTLEKYARALEGMFLRTGTFDSVRSPEAFNRIRTKIYKHRSKVGCFVRKLFPSNLGGAIRPSLFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBG5</accession>
    <name>A4SBG5_OSTLU</name>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="3" type="ORF">OSTLU_19135</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
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            <taxon>Viridiplantae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001422576.1"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <location>
            <begin position="263"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        <location>
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            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP00930.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="980" mass="107295" checksum="0F5AA55CF71D7616" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQX6</accession>
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        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_23877</name>
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    <organism evidence="6 7">
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        <lineage>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001415429.1"/>
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    <dbReference type="GeneID" id="4999596"/>
    <dbReference type="Gramene" id="ABO93758">
        <property type="protein sequence ID" value="ABO93758"/>
        <property type="gene ID" value="OSTLU_23877"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_23877"/>
    <dbReference type="HOGENOM" id="CLU_343688_0_0_1"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
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        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="227"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="143"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="359"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="824" mass="88281" checksum="F754E4E1121DF638" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQX9</accession>
    <name>A4RQX9_OSTLU</name>
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        <recommendedName>
            <fullName evidence="1">NFACT RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415808.1">
        <property type="nucleotide sequence ID" value="XM_001415771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQX9"/>
    <dbReference type="GeneID" id="4999672"/>
    <dbReference type="Gramene" id="ABO94100">
        <property type="protein sequence ID" value="ABO94100"/>
        <property type="gene ID" value="OSTLU_28821"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28821"/>
    <dbReference type="eggNOG" id="ENOG502S3C9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_889482_0_0_1"/>
    <dbReference type="OMA" id="MHAAGCP"/>
    <dbReference type="OrthoDB" id="497185at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:ribosomal large subunit binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="123"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="253" mass="27673" checksum="CA9A8C7CAAB6E17E" modified="2007-05-15" version="1">MRKETQRRIERALKKVGKATTKLRVARETVEALMAKEDASEAELAACPDVDAIASDLTSCKTELNDLNALSDVLRGCKSVNSPMFVDDAYERAKALRVDDAPPARPPRVPKVKGPRSDKPRMPYWTFVSVDGIDIRVGRTSSDNDSVSCDPQCRDSRDWWMHAAGCPGSHVVIRYTGDDLPKETMIDAAVLAAANSKANQVGRAPVSLVRCRQVSKPRGAKPGLVQLSGDVRTVTVNVKDEAARLERLMTTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR21</accession>
    <name>A4RR21_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415491.1">
        <property type="nucleotide sequence ID" value="XM_001415454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR21"/>
    <dbReference type="GeneID" id="4999957"/>
    <dbReference type="Gramene" id="ABO93783">
        <property type="protein sequence ID" value="ABO93783"/>
        <property type="gene ID" value="OSTLU_13734"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13734"/>
    <dbReference type="HOGENOM" id="CLU_867114_0_0_1"/>
    <dbReference type="OMA" id="AVWIAND"/>
    <dbReference type="OrthoDB" id="10386897at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36741" checksum="02E7E5956A6CB08D" modified="2007-05-15" version="1">MSDERDARDAATTPKPPRTPEKTLVHRLAQPKSADELVALVPKTILLTEHAEGASAMARAEVLDHFSVMFWIANDCCWSQETTWVFVPMAFVVIFFTHNVWASRNDANEFRHALAVFFWLVGANSCWVWMDFYGSVYALEVWCVICFATSVLIEAAQLTVLAVPAMNNAGEVDTQDVTDAFQAIAILSWAAHDLTVFLYYNLSSVSQDYCRVAWWILGAVIVFQVSYYLYLQIKIYRARPESSGVDYALALFAWSIGCIFWEFGDFYATDHQDPEPVFRPPRHVDNFRWWSFWIIVIGALPLAVWCVRHSLNILAWSKKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR93</accession>
    <name>A4RR93_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_7303</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415860.1">
        <property type="nucleotide sequence ID" value="XM_001415823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR93"/>
    <dbReference type="STRING" id="436017.A4RR93"/>
    <dbReference type="GeneID" id="4999654"/>
    <dbReference type="Gramene" id="ABO94152">
        <property type="protein sequence ID" value="ABO94152"/>
        <property type="gene ID" value="OSTLU_7303"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7303"/>
    <dbReference type="eggNOG" id="KOG2255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062456_4_1_1"/>
    <dbReference type="OMA" id="HDELQVP"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1470:FF:000001">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="Peptidyl-tRNA hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="189" mass="20611" checksum="DD884938B73B5F9F" modified="2007-05-15" version="1" fragment="single">WLICGLGNPGAKFAGTRHNVGFEVVDALARRAGIELTSTKHRAVLGVGKLGRSAVVLAKPQTFMNLSGKSVREMMRAFKIGKSRIVIVYDDLETKLGELRMKTSGSHGGHNGVRSVIDDATRGDRSFARVKIGIGRPKDENTAVYEYVLSRFDEDDAVKVNGAVEDAVEALQEVLLDNKFGDAMTRYNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRA4</accession>
    <name>A4RRA4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415864.1">
        <property type="nucleotide sequence ID" value="XM_001415827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRA4"/>
    <dbReference type="STRING" id="436017.A4RRA4"/>
    <dbReference type="GeneID" id="4999945"/>
    <dbReference type="Gramene" id="ABO94156">
        <property type="protein sequence ID" value="ABO94156"/>
        <property type="gene ID" value="OSTLU_28946"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28946"/>
    <dbReference type="eggNOG" id="KOG2936">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049046_2_0_1"/>
    <dbReference type="OMA" id="GDCEVNQ"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08892">
        <property type="entry name" value="SRPBCC_Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="ASHA1/2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF8">
        <property type="entry name" value="AHA1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="2">
        <location>
            <begin position="29"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="38311" checksum="2D12A757875E5BB6" modified="2007-05-15" version="1">MARAGEGDARWIVEDRADGTNVHGWHWQEKDALPWARARLDALCARRAIDGDGDGDGDGVVTRVAVTGVTKCEGEAYVNKRKGKIIPGYELELEMSYVAELRDGKTRDGKIRLPYVADENADEDPECVVVPANDTNEDARVKALILKSIVPKVLEGVRTWVKEMAAGGPGGDAPASAEAAAEAAEAAEAAKAAKAKSSASVPRSDKTAPLSQTNHTIRLTENFYCRPRDICDALLDGNRVQHFTQSRASGLNGSTGKFEMFDGNVQGETTEYVPGEKIVQNWRFSSWPDDHFSVVTVTFREPEPGNCFVDLVQTNVPECDKFGNETVMDTTENGWKNLIFGRIRQVFGYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRH3</accession>
    <name>A4RRH3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415901.1">
        <property type="nucleotide sequence ID" value="XM_001415864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRH3"/>
    <dbReference type="STRING" id="436017.A4RRH3"/>
    <dbReference type="GeneID" id="4999444"/>
    <dbReference type="Gramene" id="ABO94193">
        <property type="protein sequence ID" value="ABO94193"/>
        <property type="gene ID" value="OSTLU_92168"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92168"/>
    <dbReference type="HOGENOM" id="CLU_1368199_0_0_1"/>
    <dbReference type="OrthoDB" id="537700at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052276">
        <property type="entry name" value="Diphthamide-biosynth_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44240">
        <property type="entry name" value="DNAJ DOMAIN (PROKARYOTIC HEAT SHOCK PROTEIN)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44240:SF10">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="200" mass="21453" checksum="72EBA82032467391" modified="2007-05-15" version="1">MPKADDPHVVLGVAKGAAVDEIKKAFRARARVLHPDTSDGTTTEEEFHALKAAYEALLKRRGAEADPQDEVYGPGMRARLDAARAWRERSAMKSSGVAPAREWNEINAAASGTQRRASGRAFDAEAHQTLEELLAARRAAKSNTVSSVKSALGAGIVEGKVSRGSRGLLVVGCGLIIGLIATRKVMHKMEEREKRAVKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRM2</accession>
    <name>A4RRM2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_29066</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasmic vesicle membrane</location>
            <topology evidence="2 7">Peripheral membrane protein</topology>
            <orientation evidence="2 7">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <location evidence="7">Coated pit</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="7">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the clathrin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415926.1">
        <property type="nucleotide sequence ID" value="XM_001415889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRM2"/>
    <dbReference type="STRING" id="436017.A4RRM2"/>
    <dbReference type="GeneID" id="4999959"/>
    <dbReference type="Gramene" id="ABO94218">
        <property type="protein sequence ID" value="ABO94218"/>
        <property type="gene ID" value="OSTLU_29066"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29066"/>
    <dbReference type="eggNOG" id="ENOG502R77G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1144165_0_0_1"/>
    <dbReference type="OMA" id="KNTHPVK"/>
    <dbReference type="OrthoDB" id="5512at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0168">Coated pit</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="136"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="243" mass="25945" checksum="64EF5505A25A9EED" modified="2007-05-15" version="1">MDDGSVHEDAGAQEAQMQMNSSFQSVSSLSASKDFGTNAGAEDSGHADGGLDDFGDFAAEPAAVEQMTAEVGQMAVEHAAPAEPAAPAPEEAPMEPVAVMSNAGSASALSESDFAAPEQSVMAEEPAVNMYNSPHLQAFRAEQAKQLAEREEAEKREIERIKEEAQAELELMDSQRAKQISSAKQANRERQTAEEELFANASGWEAVSNYVSDENLVPDSLTDLSKMRSLIRVLKNTPPVKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRR8</accession>
    <name>A4RRR8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415948.1">
        <property type="nucleotide sequence ID" value="XM_001415911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRR8"/>
    <dbReference type="GeneID" id="4999803"/>
    <dbReference type="Gramene" id="ABO94240">
        <property type="protein sequence ID" value="ABO94240"/>
        <property type="gene ID" value="OSTLU_13925"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13925"/>
    <dbReference type="HOGENOM" id="CLU_919490_0_0_1"/>
    <dbReference type="OMA" id="CAYDCAM"/>
    <dbReference type="OrthoDB" id="10423667at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019188">
        <property type="entry name" value="SNAPC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15131">
        <property type="entry name" value="SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15131:SF3">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09808">
        <property type="entry name" value="SNAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="303" mass="33221" checksum="7893FDF31A87CC2C" modified="2007-05-15" version="1">MPACDERELRGVEIDVMDLIERHARDVDRARDDGDDAYAAAMSFANFKARWCERRFSNVHLGKPAQQTYNGYVQCAYDCAMKYARTGKTLATRATGVYCVYALHETQLEGEPVRAYACPRALEALAETIEACDAIGAHAVGRIVKKMMDAESFVVGARDTTNAPMSRMGAGAPEVFKNFDEKEAIHEALAHLLQERLDDELDEMSASASEYTRSLAGATRLEESTLAAPVTICSTVQTLLTKTKTKVERALKPPIEAGEPLMLPGIPVNLPKAKKKKTQSKTQAAPKRAEKLASMPSFAPSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRZ9</accession>
    <name>A4RRZ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_39942</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415654.1">
        <property type="nucleotide sequence ID" value="XM_001415617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRZ9"/>
    <dbReference type="STRING" id="436017.A4RRZ9"/>
    <dbReference type="GeneID" id="4999805"/>
    <dbReference type="Gramene" id="ABO93946">
        <property type="protein sequence ID" value="ABO93946"/>
        <property type="gene ID" value="OSTLU_39942"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39942"/>
    <dbReference type="eggNOG" id="KOG0670">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_5_15_1"/>
    <dbReference type="OMA" id="PEIIMGH"/>
    <dbReference type="OrthoDB" id="3967at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14135">
        <property type="entry name" value="STKc_PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000078">
        <property type="entry name" value="Serine/threonine-protein kinase PRP4 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044092">
        <property type="entry name" value="STKc_PRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF103">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="28"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO93946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="40610" checksum="A0C0B9FB7272F7D3" modified="2007-05-15" version="1">MSKGLADNWDDAEGYYCARIGEVLDGRYTITAHLGKGVFSNVLRAVDESKTEGEPSEVAIKVIRCNDSMYKAAQLEIDILQKLSGSDPENKRHCVRFVRHFEYREHVFMVFESLAMNLREVIKKFGRNVGINIKAVQAYATQLFIALRHLKNCGVVHADIKPDNVLVNESHNVLKLCDFGSAMFDGDNELTPYLVSRFYRAPEVILGLPYSHPMDLWSVGCCLYELFTGNISFPGRSNNHMLKLMLELKGPVPKKLLRRALFKDNHYDPMGIFSVVEEDPVTKKSIRRLVRDAKPTKDLSKIFTRDSDMSDGERKKALQLADLLNQIFNIDPEKRITVLDALQHPFIVEKISSASDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS12</accession>
    <name>A4RS12_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Micro-fibrillar-associated protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416001.1">
        <property type="nucleotide sequence ID" value="XM_001415964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS12"/>
    <dbReference type="STRING" id="436017.A4RS12"/>
    <dbReference type="GeneID" id="4999843"/>
    <dbReference type="Gramene" id="ABO94293">
        <property type="protein sequence ID" value="ABO94293"/>
        <property type="gene ID" value="OSTLU_29207"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29207"/>
    <dbReference type="eggNOG" id="KOG1425">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078096_0_0_1"/>
    <dbReference type="OMA" id="REEDHEM"/>
    <dbReference type="OrthoDB" id="1111734at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="29486" checksum="91C8B6DEABB9B396" modified="2007-05-15" version="1">MFKPVFVRKIERDTIEERDKMLAELDAEAAKTEAAKAAKKAESKKLVEVEVKREEALAAAMDEMEPSDVDTDDELDDALEFDAWKSRELERLKTDRIQRELIFREREEQERIRSMTEEERDLYHAKRLAKRAEQEKEKPKMAFMQKYYHKGAFFQESADDAFGTAGPDEIYKRDFSAPTAEEKFDKSILPAAMQVRKGKFGRAGQTKWTHLAAEDTSAARKGDDDDLWSGRDKSVRAIKDKMLAKQGGLRDAARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS36</accession>
    <name>A4RS36_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_29231</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416010.1">
        <property type="nucleotide sequence ID" value="XM_001415973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS36"/>
    <dbReference type="STRING" id="436017.A4RS36"/>
    <dbReference type="GeneID" id="4999721"/>
    <dbReference type="Gramene" id="ABO94302">
        <property type="protein sequence ID" value="ABO94302"/>
        <property type="gene ID" value="OSTLU_29231"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29231"/>
    <dbReference type="eggNOG" id="KOG1487">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044997_0_0_1"/>
    <dbReference type="OMA" id="SAKHPGQ"/>
    <dbReference type="OrthoDB" id="603at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019003">
        <property type="term" value="F:GDP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17230">
        <property type="entry name" value="TGS_DRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000003">
        <property type="entry name" value="Developmentally-regulated GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000740">
        <property type="entry name" value="Putative GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="67"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="294"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="374" mass="41743" checksum="A2B3CBDA5AE1356E" modified="2007-05-15" version="1">MSDGAIMDKIAAIELEISRTQVNKATSSHIGSLRARLCKLQRELVELAGPKGGPKGEGFDVTKTGDCRVGLVGFPSVGKSTLLTKLTGVFSEAAAYEFTTLTCVPGVIKYRGARIQLLDLPGIIEGAKDNKGRGRQVISTARTCDVIIIVLDALKPFTHRKLIEHELEGVGIRLNKKPPAITFNRKEKGGIAFTPNPNGKTTFLDEETVKSICAEYKIHNADVKLFADCTDEELIDVIEGNRIYTPAVYAVNKMDSVSLEELQLMDDMKHYVMTSSEKEWNLDGLLEKVWEYLDLIRVYTMPRGTQPNFDEPIILHKKNCTVEDFCNKLHKTIIRTFKHALVWGTSVKHRPQRVGKEHVLEDEDVVQIQKTHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSC2</accession>
    <name>A4RSC2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1517 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_35945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416517.1">
        <property type="nucleotide sequence ID" value="XM_001416480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSC2"/>
    <dbReference type="STRING" id="436017.A4RSC2"/>
    <dbReference type="GeneID" id="5000208"/>
    <dbReference type="Gramene" id="ABO94810">
        <property type="protein sequence ID" value="ABO94810"/>
        <property type="gene ID" value="OSTLU_35945"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35945"/>
    <dbReference type="eggNOG" id="ENOG502QUI9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047333_4_1_1"/>
    <dbReference type="OMA" id="HWTIGSA"/>
    <dbReference type="OrthoDB" id="542507at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010903">
        <property type="entry name" value="DUF1517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053023">
        <property type="entry name" value="FLAP_modulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33975">
        <property type="entry name" value="MYELIN-ASSOCIATED OLIGODENDROCYTE BASIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33975:SF2">
        <property type="entry name" value="MYELIN-ASSOCIATED OLIGODENDROCYTE BASIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07466">
        <property type="entry name" value="DUF1517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="22680" checksum="AE4EF00EA9E1C237" modified="2007-05-15" version="1">MLALAASNALRNATGRGGFGDGLSAGGDSISVVKIQVGLLGSARALQKDLERIADKADTSSPDGLHFVLSETALALLRNPEYCVYGYAASKVCRGPEQAEETFNDYSIDERGKFEKETLVNVNARRRAETVGVDPAADTNDYILVTIIAAADGGVKMPDITDANDLKTALKRLGAVRVEALQAVEVLWTPQEDGDVLTQTELLRDYPILVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSC4</accession>
    <name>A4RSC4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spc7 kinetochore protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_14376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416270.1">
        <property type="nucleotide sequence ID" value="XM_001416233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSC4"/>
    <dbReference type="STRING" id="436017.A4RSC4"/>
    <dbReference type="GeneID" id="5000426"/>
    <dbReference type="Gramene" id="ABO94563">
        <property type="protein sequence ID" value="ABO94563"/>
        <property type="gene ID" value="OSTLU_14376"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14376"/>
    <dbReference type="eggNOG" id="ENOG502SE28">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_287204_0_0_1"/>
    <dbReference type="OMA" id="CRNEFPR"/>
    <dbReference type="OrthoDB" id="10379006at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013253">
        <property type="entry name" value="Spc7_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08317">
        <property type="entry name" value="Spc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spc7 kinetochore protein" evidence="3">
        <location>
            <begin position="545"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="601"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="769"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1074" mass="113626" checksum="AEDD576EB27DB06D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSU4</accession>
    <name>A4RSU4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Xab1</name>
        <name evidence="6" type="ORF">OSTLU_119578</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416433.1">
        <property type="nucleotide sequence ID" value="XM_001416396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSU4"/>
    <dbReference type="STRING" id="436017.A4RSU4"/>
    <dbReference type="GeneID" id="5000132"/>
    <dbReference type="Gramene" id="ABO94726">
        <property type="protein sequence ID" value="ABO94726"/>
        <property type="gene ID" value="OSTLU_119578"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119578"/>
    <dbReference type="eggNOG" id="KOG1532">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037460_1_0_1"/>
    <dbReference type="OMA" id="QCQNPQI"/>
    <dbReference type="OrthoDB" id="243313at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd17870">
        <property type="entry name" value="GPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030230">
        <property type="entry name" value="Gpn1/Npa3/XAB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF8">
        <property type="entry name" value="GPN-LOOP GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="248" mass="27329" checksum="75CABD2524DDCD3E" modified="2007-05-15" version="1">MSVQRGRVCILVGMAGSGKTSLLERLVDFTHAAGKSSYVINLDPAAHNLPYQANIDIRDTIDYKAVMKEYSLGPNGAILTAANLFATRFDKVISICEQRATEYEYFFVDTPGQIEIFTWSASGMMITEMIASSFSTDILFVMDTPQCQNPQILMSNMLQAVSVLYRSRLNVVLVFNKIDVAPHAPLLKLLTDVNIFQEKLENASNFSSALTSSLNLILQEFYEHLNIVGVSAIQGTGIGDFVNVLQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTG6</accession>
    <name>A4RTG6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29883</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416315.1">
        <property type="nucleotide sequence ID" value="XM_001416278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTG6"/>
    <dbReference type="STRING" id="436017.A4RTG6"/>
    <dbReference type="GeneID" id="5000178"/>
    <dbReference type="Gramene" id="ABO94608">
        <property type="protein sequence ID" value="ABO94608"/>
        <property type="gene ID" value="OSTLU_29883"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29883"/>
    <dbReference type="eggNOG" id="ENOG502QS9K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_403031_0_0_1"/>
    <dbReference type="OMA" id="AYTGCGP"/>
    <dbReference type="OrthoDB" id="511314at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23132">
        <property type="entry name" value="D-ALANINE--D-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23132:SF0">
        <property type="entry name" value="D-ALANINE-D-ALANINE LIGASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="3">
        <location>
            <begin position="437"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="683" mass="71842" checksum="37CD324A27CBBE96" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTL8</accession>
    <name>A4RTL8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_14070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416050.1">
        <property type="nucleotide sequence ID" value="XM_001416013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTL8"/>
    <dbReference type="GeneID" id="5000367"/>
    <dbReference type="Gramene" id="ABO94342">
        <property type="protein sequence ID" value="ABO94342"/>
        <property type="gene ID" value="OSTLU_14070"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14070"/>
    <dbReference type="HOGENOM" id="CLU_761613_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="364" mass="39216" checksum="DDA7D245EA47BC9B" modified="2007-05-15" version="1">MANVPRRAPLGTLSFNRDDDHHTVASTSFASPASKFAGRSTASLDDDGDAYAVASVNTPEMCAMADGRVGSSHEIALSLVVERDRAIERELEMAAFARAEARRCDETTRALVADVEDLTVALGETDAHVARMRWLWAIRAVVSLVRWDRERREARKAKAKARRLATQLARIEKYIATAACDFDDLNAKLVKEANDAKMARAEAREAWEMLARERAARAESPAESSAALAPPANPSTPPARRAANARRREAKDACASVAAHVESLLANSPSKQLNQLALAQREAADRARATLADHPRTSDGALDPKDVVALIAVHALERCAERSSSDGRRAFARAAKRFETVARACVAGDDAAPLTAAASSSRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTR5</accession>
    <name>A4RTR5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS family transporter: sugar</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_30357</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416832.1">
        <property type="nucleotide sequence ID" value="XM_001416795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTR5"/>
    <dbReference type="GeneID" id="5000831"/>
    <dbReference type="Gramene" id="ABO95125">
        <property type="protein sequence ID" value="ABO95125"/>
        <property type="gene ID" value="OSTLU_30357"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30357"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_5_1"/>
    <dbReference type="OMA" id="ICRIRDS"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="11"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="502" mass="51590" checksum="09CC2FED73AA6F26" modified="2007-05-15" version="1">MAPGRRGNAHAYRFALLGGLSLGYDVALVGGILPTLERTLALSAAARGVVVASAKLGGALGAFVGAALMRSHGRGRSASAMTLACSACGSAATWASAEAGDATGMALGRVALGVGVGGVAVIAPAYCGETSEVGARGSVGACFELSVCAGMALANALTWFSPQKTLGLVLFSPAVLGFWSAIVFAMSVESPRWLFRRGDENGARDALRATGADAATVEEEIGEILAEERALGIGFDGGAGDDAGFWRSFVESTVGGVREAMSGDERRAVRLALAMAVLNQMCASTSVINYGSSVFRRLANDASASNGDMDVYNMYTGVIILCKTVGVAASIAMVDSVGRRPLLLFGSAASGFGLCVACFGYAAKSVGWTLFGLCAFILAFSSSFASVFWVLVSELFSMRAKSSAIALVTATLFASGALSDSIFPSMISTIGAGTFVVYAIVCFASTTFVYLYIPETARKPLKEIQSAMKSGLSGYAEIHASSEHEDRGTRVELAVTRDTNGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTS9</accession>
    <name>A4RTS9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">BCCT family transporter: glycine betaine/carnitine/choline</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_33799</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416550.1">
        <property type="nucleotide sequence ID" value="XM_001416513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTS9"/>
    <dbReference type="GeneID" id="5000886"/>
    <dbReference type="Gramene" id="ABO94843">
        <property type="protein sequence ID" value="ABO94843"/>
        <property type="gene ID" value="OSTLU_33799"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33799"/>
    <dbReference type="eggNOG" id="ENOG502QRGP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010118_5_2_1"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047:SF7">
        <property type="entry name" value="HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="508" mass="56391" checksum="0590BB4A67D6EF82" modified="2007-05-15" version="1" fragment="single">MATTTLWGFTIGVLSREEAAEEFFGKATLWISNNFTWFYTLTQNAWIFVVIFVLFRKRYANIKLGQPDDRPDYSDLVWFTLIFTTGLGTGIFYFGVSEPMYYYRDDSKLLGTATNYIAKIPFMNDDQRANMAMFVTFLHWGLHGWATYILVALTLGVVHYRLGRPLTLRSAFYPIVGDYVNGLFGDLIDSMSIACTTFGLCTSLGLGASSINTILHRMSASIPDDDDNTKSAIIWGITALTTGALVSGLHRGVITFAIVAFSILLALIMILFMLDNTWYLANSFTQQIGTYLQYVILGGFDNDAIAQLNIDSPTSFMDTWTVFYWAWWITWAPFVGMFYAKISRGRTIRSLILVGMFAPMFLGFFAISVLGSLGIRMQRIAELALGAAPDWQKGVVNCGALGYLENTPPYKNLTTLLQTLVLLGVILFFVTSADAGAFVDDKIAANGMENPPVLQKVWWSITQGATAQALLSSTKNGLSTLQSVSICAALPYTFALNYMCVALFRAMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTY2</accession>
    <name>A4RTY2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416864.1">
        <property type="nucleotide sequence ID" value="XM_001416827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTY2"/>
    <dbReference type="GeneID" id="5000909"/>
    <dbReference type="Gramene" id="ABO95157">
        <property type="protein sequence ID" value="ABO95157"/>
        <property type="gene ID" value="OSTLU_30427"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30427"/>
    <dbReference type="HOGENOM" id="CLU_1573270_0_0_1"/>
    <dbReference type="OMA" id="CQCLIAI"/>
    <dbReference type="OrthoDB" id="1043111at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="18293" checksum="7E5137EA420E6D70" modified="2007-05-15" version="1">MDDMEYWKDVGLGKGAWQCDASGGREILPQDEATVFEELPSAHSPRFALLPSVPTVAARTDDRHVAVFFDGCRYRCEFDVDGGTVGELARALCAGGLGSGADMTTGARQKLDGPESLVLFYCGKRLDDDDNKVSSYGVPRGCKILLGIDRALVERAEAGLGPGEDDDFWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTZ8</accession>
    <name>A4RTZ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Uridine 5'-monophosphate synthase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
            <ecNumber evidence="6">4.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PYR5</name>
        <name evidence="19" type="ORF">OSTLU_19418</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>orotidine 5'-phosphate + H(+) = UMP + CO2</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EC" id="4.1.1.23" evidence="6"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416873.1">
        <property type="nucleotide sequence ID" value="XM_001416836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTZ8"/>
    <dbReference type="STRING" id="436017.A4RTZ8"/>
    <dbReference type="GeneID" id="5000819"/>
    <dbReference type="Gramene" id="ABO95166">
        <property type="protein sequence ID" value="ABO95166"/>
        <property type="gene ID" value="OSTLU_19418"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19418"/>
    <dbReference type="eggNOG" id="KOG1377">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049275_1_0_1"/>
    <dbReference type="OMA" id="SAKHVCG"/>
    <dbReference type="OrthoDB" id="10263753at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000092">
        <property type="entry name" value="Uridine monophosphate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000025">
        <property type="entry name" value="Uridine monophosphate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010382">
        <property type="entry name" value="PRK13809.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278:SF9">
        <property type="entry name" value="URIDINE 5'-MONOPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="18">
        <location>
            <begin position="244"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="16">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="16">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="16">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO95166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="474" mass="51324" checksum="7E08B20D879C2B8C" modified="2007-05-15" version="1">MDAKIDALVMRLHEIEAVKFGEFKLKSGIMSPIYVDLRVIVSYPDVLTAVAECMWETLKANGATFDNMCGVPYTALPIATCMSLAHDCPMLMRRKEVKAYGTKKQIEGAFEAGQTCLCVEDLVTSGASVMETVEPLESVGLKVKDVVVLIDREQGGEARLASHGLRLHSVLPLSRVLKTLEAAGKMSSELVQNVKDFIAANQTMPVAGAEVKKPTRMSYTARSELTDNACAKQLFKLMETKKTNLCVAADVDTAKELLEMAEILGPEICMLKTHCDLYPDFTESFGAQLMAIAEKHNFMIFEDRKFADIGNTVVGQYSSGVHKIADWSHITNAHIVPGSGIIDGLKSVGLSKGRGLLLLAEMSSKGTMAKGEYTEAAIGMAAQHPDFVMGFISTNPKAWKAEWSKGLINMTPGVQLQVGGDAMGQQYNTPHNVIVENGSDVIIVGRGIYKASDPAAAAKEYRAAGWEAYQTSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU59</accession>
    <name>A4RU59_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416616.1">
        <property type="nucleotide sequence ID" value="XM_001416579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU59"/>
    <dbReference type="GeneID" id="5001002"/>
    <dbReference type="KEGG" id="olu:OSTLU_92415"/>
    <dbReference type="HOGENOM" id="CLU_043884_0_0_1"/>
    <dbReference type="OMA" id="HTGHQHW"/>
    <dbReference type="OrthoDB" id="495721at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="488" mass="56065" checksum="38F02EB3EB6E540B" modified="2007-05-15" version="1" fragment="single">LKTFYPGDQTVRNASESWARLMFSRDGFSFGRMYEQRFETQVRIDAKDGAIEETKEGYTVQGKIPDRPKFTTKLKTSDMLKDEYNRAGRQKKCYFYVELEEPVLVLHDDGDELRHHLELDAHDLEFEQFKCTYFHGVQRPVNGGSIESGKWEIKDERESGGKVAIMSSATTLTMLSAYHRTLVNHQAFAKHHGYASILALVSRDTLAGRSGKFAKHMAMGVQTLKKDHDMTCHVDLDAWFASWDPLSYYSKNWPGDKNLFFGDTGQVWLNSGLMCARSVDWTVDFFERVLNAVHEKGMDENSNPVKFGFKRDQPAMWHVLATEWAQKDNIPYLGTKCPRWDSCNPDSNPIECWHWCFWDAFQRRPKGWDGLHDLNKLSNVYLDPQENEPKMHRMCLASCQSVLSRANMALCSTITGSAGCLPKDVDKMSLCDGRGCLQQLTSKGGAWLKHTGHQHWRDVLPRCIPRNSQESEREKRSYLSLCDTKRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUA2</accession>
    <name>A4RUA2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_34044</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416638.1">
        <property type="nucleotide sequence ID" value="XM_001416601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUA2"/>
    <dbReference type="STRING" id="436017.A4RUA2"/>
    <dbReference type="GeneID" id="5000589"/>
    <dbReference type="Gramene" id="ABO94931">
        <property type="protein sequence ID" value="ABO94931"/>
        <property type="gene ID" value="OSTLU_34044"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34044"/>
    <dbReference type="eggNOG" id="ENOG502QQ82">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048809_4_0_1"/>
    <dbReference type="OMA" id="WDATYER"/>
    <dbReference type="OrthoDB" id="207175at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF90">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR AIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="6">
        <location>
            <begin position="9"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="6">
        <location>
            <begin position="116"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="22289" checksum="9CD16FCFCCCA42F5" modified="2007-05-15" version="1">MKSTNRSSKWKGVTRHKITSRWEAHLWDATYERVRKKSSGGRTRGRQVYLGGWISELDAARAYDLAALRFFGTRQVLNFDVSNYTEEIKAMQEYSPADWVCELRRRSSGFSRGVSAYRGVTSHKGKNSKGKWEARIGRVMGNKYLYLGTYPTERAAAEAYDCAALLYRDSKAVTNFDRSNYSEEEIANAGLGAKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUC9</accession>
    <name>A4RUC9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUC9"/>
    <dbReference type="GeneID" id="5000756"/>
    <dbReference type="Gramene" id="ABO95231">
        <property type="protein sequence ID" value="ABO95231"/>
        <property type="gene ID" value="OSTLU_30577"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30577"/>
    <dbReference type="HOGENOM" id="CLU_2780397_0_0_1"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7416" checksum="383DE12414A34F3E" modified="2007-05-15" version="1">MEDGAVRADWRAIDVVDDAWANDALPDDAVRLNAEMAAPVDDAEEGNEDGGTGGNEDETWKDLGLNDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUR3</accession>
    <name>A4RUR3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417005.1">
        <property type="nucleotide sequence ID" value="XM_001416968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUR3"/>
    <dbReference type="GeneID" id="5000796"/>
    <dbReference type="Gramene" id="ABO95298">
        <property type="protein sequence ID" value="ABO95298"/>
        <property type="gene ID" value="OSTLU_24266"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24266"/>
    <dbReference type="HOGENOM" id="CLU_400847_0_0_1"/>
    <dbReference type="OMA" id="VLMHWSK"/>
    <dbReference type="OrthoDB" id="10522057at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="687" mass="75826" checksum="7D9C55D0A1FFEF60" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUX7</accession>
    <name>A4RUX7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_3784</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417038.1">
        <property type="nucleotide sequence ID" value="XM_001417001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUX7"/>
    <dbReference type="GeneID" id="5000808"/>
    <dbReference type="Gramene" id="ABO95331">
        <property type="protein sequence ID" value="ABO95331"/>
        <property type="gene ID" value="OSTLU_3784"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3784"/>
    <dbReference type="eggNOG" id="KOG4332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034007_0_0_1"/>
    <dbReference type="OMA" id="WIQGAYL"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37159" checksum="4065BB7BA4F59A1C" modified="2007-05-15" version="1" fragment="single">RRYVAVYALGTFGDWIQGAYLYAAYRRHGLVKREIGYIYVLGYVVSATIGTTCAALGDTRGHRALAVAYGTLYAASCLLLRSSAMTTLIASRILGGIAYSLLFTNFESWVITEADAMGIDRKKLAGVFSVATLFNGASAVLAGLVGNFVVEFAESSQFSWIGMDEVRLEMGAEADTSGSVVMMSKNVISSAVRMIMSSVELFRLGAANSLYEGALHLFVFVWTPVLEKRSAIDATVPYGSVFSAFMVCKMFGSQAFKVLEARIPAENLLRMVLVGSAVSFSIAVLFTGYWVTLAAFCAFEFGLGIYWPVMSILRAKYVPNKMRATMTSAFRIPLNILVVALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV71</accession>
    <name>A4RV71_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417087.1">
        <property type="nucleotide sequence ID" value="XM_001417050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV71"/>
    <dbReference type="GeneID" id="5001063"/>
    <dbReference type="Gramene" id="ABO95380">
        <property type="protein sequence ID" value="ABO95380"/>
        <property type="gene ID" value="OSTLU_30869"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30869"/>
    <dbReference type="eggNOG" id="ENOG502RZQG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036026_0_0_1"/>
    <dbReference type="OMA" id="RWLAWPT"/>
    <dbReference type="OrthoDB" id="5130at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="2">
        <location>
            <begin position="211"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="353" mass="38056" checksum="3ED7135EB6BA452A" modified="2007-05-15" version="1">MTVIQRNKFREETRFALGELRDVARVAVVYGDAAKVERDLMAATPYRRRLEQSRILVVPVVERESAAATSAVADVGPGRWELLKDVVKAFPGAGAGRWLAWPTRNDDWSGYFRRLMGDAAASGGYLTISTSGMIRGSGVGAPNWDVLLSTFPRNRPGNKQDEEAEKAWKRATLDSSEALTSKEEGTRIASGGGRGAISQALPRDVPELSEIVAIHEGFYRALGEGDEEAMAAIWSKSKTRQSALAPLVDKGARLDGWDVVLRPDRRPQGIIVSDLDVTIEKGLATLTGLETVANGATLLCTQTFERDDTDGAWIMTGHTTIPYGADVVAKVVLRCDASGCIALPAKSVASSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV89</accession>
    <name>A4RV89_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS family transporter: hexose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_3240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417096.1">
        <property type="nucleotide sequence ID" value="XM_001417059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV89"/>
    <dbReference type="GeneID" id="5001133"/>
    <dbReference type="Gramene" id="ABO95389">
        <property type="protein sequence ID" value="ABO95389"/>
        <property type="gene ID" value="OSTLU_3240"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3240"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_5_1"/>
    <dbReference type="OMA" id="WAITASF"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17315">
        <property type="entry name" value="MFS_GLUT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="430" mass="44640" checksum="389142DD43B65BE1" modified="2007-05-15" version="1" fragment="single">VAVAALGAFSFGYHCGVVNPALEALASDIGIARDVAAKGAVVSSMLMGAAFGSFAAGASADKFGRKKSLALAGVALALGSAACAAATTLRTMLAGRAIVGVGVGLVSILVPMYVSELSPPEHRGVLGSGPQLSIGFGILVAMFLGLPLQGVDVDPAWWRTMFWLATVPAVALATLANGIPESPSWLRSKGHFQEADAVESKQFGAVAPKRADDMGSTKVATWQETLQGRSNRRAVITGPMLFFIQQFAGINAIIYFSTAIFQSAGIESGVLASVAVCVVNIVGSVIATGLLDKTGRKPLLMYSFLGMAVSCVGLAIAGAFPAMVMAPALSLFSVLSYVFIFGMGAGPVPGLLSSEIFAPAVRGKGMSLCFLAHWIFNFCIGQGFLPAVEYFGASVVYMFFAAFSMFGFFFTQAYVVETKGKSLEQIAVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVF4</accession>
    <name>A4RVF4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATPase AAA-type core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417125.1">
        <property type="nucleotide sequence ID" value="XM_001417088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVF4"/>
    <dbReference type="STRING" id="436017.A4RVF4"/>
    <dbReference type="GeneID" id="5001638"/>
    <dbReference type="Gramene" id="ABO95418">
        <property type="protein sequence ID" value="ABO95418"/>
        <property type="gene ID" value="OSTLU_92546"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92546"/>
    <dbReference type="eggNOG" id="KOG0740">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_527230_0_0_1"/>
    <dbReference type="OMA" id="HMKCVLL"/>
    <dbReference type="OrthoDB" id="3046016at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052267">
        <property type="entry name" value="N-DRC_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14690">
        <property type="entry name" value="IQ MOTIF CONTAINING WITH AAA DOMAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14690:SF0">
        <property type="entry name" value="IQ MOTIF CONTAINING WITH AAA DOMAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="2">
        <location>
            <begin position="295"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="517" mass="57362" checksum="5D371480A85078BD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVV8</accession>
    <name>A4RVV8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TraB family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417216.1">
        <property type="nucleotide sequence ID" value="XM_001417179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVV8"/>
    <dbReference type="GeneID" id="5001601"/>
    <dbReference type="Gramene" id="ABO95509">
        <property type="protein sequence ID" value="ABO95509"/>
        <property type="gene ID" value="OSTLU_31114"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31114"/>
    <dbReference type="eggNOG" id="ENOG502S91Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_572917_0_0_1"/>
    <dbReference type="OMA" id="ERTHGIN"/>
    <dbReference type="OrthoDB" id="510339at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd14726">
        <property type="entry name" value="TraB_PrgY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF7">
        <property type="entry name" value="TRAB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="50575" checksum="3E29F65F5156F74B" modified="2007-05-15" version="1">MSLDRVDADDDPSSSTDDDGFPPGVSLGTTHGGVRVLQIDDHPEDKPKCAKKLQHPASGSEITLIGSAHVSEASAREVSRAILEGKPDLVVIELDGDRLKSLLRSASEDRPAMHAARRVASVREAFNTLVNGQLAIVAGSLGYSTIGAVLDTRPGAEFIAAVEAARDVGATVVLGDRNQRATVGRLMARVRRGSTLFDELAKTGEFLGGETDLARADAATKRSGVQKAKHILEKAGCEHSEAVIKSALEILDSGMRGIPVRVDDLMRVRKCARRVVEYVRVESFNGNPTFSPGLSKVDSAKKMSIMDWATAETVIRERDLILATALQRDPTASSVVGVVGAGHIAGIQQLWDEVESSESRAKFNEYLNEWPTDAKPVDYTNRILSGVFGAAAFTTILRRGSAGAVKFAGALVGSMLTLGAVGTYMGASGLVALGRVAVAIEDASIRAAELGNREDSARAKGAFSNMIVRDAAVPYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW65</accession>
    <name>A4RW65_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417270.1">
        <property type="nucleotide sequence ID" value="XM_001417233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW65"/>
    <dbReference type="STRING" id="436017.A4RW65"/>
    <dbReference type="GeneID" id="5001340"/>
    <dbReference type="Gramene" id="ABO95563">
        <property type="protein sequence ID" value="ABO95563"/>
        <property type="gene ID" value="OSTLU_31228"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31228"/>
    <dbReference type="eggNOG" id="ENOG502S1HB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134035_0_0_1"/>
    <dbReference type="OMA" id="NPYECTA"/>
    <dbReference type="OrthoDB" id="542764at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="153" mass="15769" checksum="91F55CA9C73529B4" modified="2007-05-15" version="1">MTTHVIMRCAPSSLARVASNAAASSSDGRARARRASRVAHRLAPARALDGVDPYETTQLVSVAGTVAALGLTALALGAKGEPKPCAACSTTGGEPCAFCDASGRRSTPVKITQRDRNDDGVLGLTRRNPYECTACKGAGMILCRACRGSGYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWB5</accession>
    <name>A4RWB5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_15111</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="15">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fatty acid desaturase type 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417298.1">
        <property type="nucleotide sequence ID" value="XM_001417261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWB5"/>
    <dbReference type="STRING" id="436017.A4RWB5"/>
    <dbReference type="GeneID" id="5001515"/>
    <dbReference type="Gramene" id="ABO95591">
        <property type="protein sequence ID" value="ABO95591"/>
        <property type="gene ID" value="OSTLU_15111"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15111"/>
    <dbReference type="eggNOG" id="ENOG502QRJK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034505_0_0_1"/>
    <dbReference type="OMA" id="HEHAYTK"/>
    <dbReference type="OrthoDB" id="1924153at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045300">
        <property type="term" value="F:stearoyl-[ACP] desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01050">
        <property type="entry name" value="Acyl_ACP_Desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.620.20:FF:000002">
        <property type="entry name" value="Stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005067">
        <property type="entry name" value="Fatty_acid_desaturase-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31155">
        <property type="entry name" value="ACYL- ACYL-CARRIER-PROTEIN DESATURASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31155:SF9">
        <property type="entry name" value="STEAROYL-[ACYL-CARRIER-PROTEIN] 9-DESATURASE 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03405">
        <property type="entry name" value="FA_desaturase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000346">
        <property type="entry name" value="Dlt9_acylACP_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="12 15" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000346-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO95591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="329" mass="36895" checksum="22CEC4C4CEFCF74B" modified="2007-05-15" version="1">MTSFAAGELSGLLKDPDTNWQPQDWLPNPESPDFLDQVAEIRKRAANIPDDLFVVLVGDMITEEALPTYMNMLNTLEGTKDNSGADAHPWAVWTRKWTAEENRHGDLMNKYLWMTGKVNMKPVETTIQKLIGSGMNPKTDNNPYLGFVYTSFQERATKISHGNTARLAKEAGDPEFAKMCGIIAADEGRHEIAYQRIIDEVLARDPDGAVLAYADMMEKQITMPAHMMCDGQHKARTGRDLFVDFAAVAERTGVYTGHDYADIMDHLNKRWDIANITGLGGEAAAAQEYLMKQPARIRKLVAFAEKRAAKKPPAKETFSWIYDRPVDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWE3</accession>
    <name>A4RWE3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417315.1">
        <property type="nucleotide sequence ID" value="XM_001417278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWE3"/>
    <dbReference type="GeneID" id="5001493"/>
    <dbReference type="Gramene" id="ABO95608">
        <property type="protein sequence ID" value="ABO95608"/>
        <property type="gene ID" value="OSTLU_31309"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31309"/>
    <dbReference type="eggNOG" id="ENOG502QST0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071721_0_0_1"/>
    <dbReference type="OMA" id="NIAQWED"/>
    <dbReference type="OrthoDB" id="537706at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045287">
        <property type="entry name" value="PAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35115">
        <property type="entry name" value="CYCLIN DELTA-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35115:SF1">
        <property type="entry name" value="PROTEIN IN CHLOROPLAST ATPASE BIOGENESIS, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="356" mass="37981" checksum="9AAFC54CE29B6996" modified="2007-05-15" version="1">MATARATAGAPARATTARWIATRSRATRATRGTRGRARATPNDGEAHAAYLRDVAATRAPAELEALARVLDALGCETIAPNARRGIHPLVMPLARTREGGVIGLMVTEDDGEATPVVEVRDGAHATMLAKSARDYVHRAIVEEEAMSDEQTTTVAAAAGAVGVSLHAHGAFKTSGKEFDVYVTTQIGKFPSSMEGLVRRHLKRNDEQSALITCDLYKATFGDWGAPHVFISDLYSKLGRDEEARDAARQALQTPWSTIGGRDAITRMIDVAGWSGKTVAEIKEVLESRRGPSAAAFDGPKSEKQLAREEGELLLDQIAAGEIESSTVNQRLAECYMNAGKPALAKFIMCGAGMPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWF2</accession>
    <name>A4RWF2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KAT8 regulatory NSL complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">NSL complex protein NSL2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Non-specific lethal 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_31317</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. Required for NSL complex stability and for transcription of intraciliary transport genes in both ciliated and non-ciliated cells by regulating histone H4 acetylation at 'Lys-5'- and 'Lys-12' (H4K5ac and H4K12ac). This is necessary for cilium assembly in ciliated cells and for organization of the microtubule cytoskeleton in non-ciliated cells. Required within the NSL complex to maintain nuclear architecture stability by promoting KAT8-mediated acetylation of lamin LMNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the NSL complex at least composed of KAT8/MOF, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417567.1">
        <property type="nucleotide sequence ID" value="XM_001417530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWF2"/>
    <dbReference type="GeneID" id="5001496"/>
    <dbReference type="Gramene" id="ABO95860">
        <property type="protein sequence ID" value="ABO95860"/>
        <property type="gene ID" value="OSTLU_31317"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31317"/>
    <dbReference type="HOGENOM" id="CLU_2350522_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044545">
        <property type="term" value="C:NSL complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026316">
        <property type="entry name" value="NSL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025927">
        <property type="entry name" value="Znf_KANL2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13453">
        <property type="entry name" value="KAT8 REGULATORY NSL COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13453:SF1">
        <property type="entry name" value="KAT8 REGULATORY NSL COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13891">
        <property type="entry name" value="zf-C3HC3H_KANSL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="KANL2-like probable zinc-finger" evidence="14">
        <location>
            <begin position="55"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00093359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO95860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="97" mass="11153" checksum="9BAB213601AA2F70" modified="2007-05-15" version="1">MRELRSMYRDQYWRLLEELRKKHRRFELRRGHGGSRDAAEEAEAARALEGTTSVCQEPSCEARSMPCVSYCFAHVALDETQKLYARAADGAPRETMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWF8</accession>
    <name>A4RWF8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
            <ecNumber evidence="2">3.5.4.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_31325</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="2"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417569.1">
        <property type="nucleotide sequence ID" value="XM_001417532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWF8"/>
    <dbReference type="STRING" id="436017.A4RWF8"/>
    <dbReference type="GeneID" id="5001240"/>
    <dbReference type="Gramene" id="ABO95862">
        <property type="protein sequence ID" value="ABO95862"/>
        <property type="gene ID" value="OSTLU_31325"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31325"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_10_1_1"/>
    <dbReference type="OMA" id="WHEQAGK"/>
    <dbReference type="OrthoDB" id="252265at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01284">
        <property type="entry name" value="Riboflavin_deaminase-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF162">
        <property type="entry name" value="RIBOFLAVIN BIOSYNTHESIS PROTEIN PYRD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="147" mass="15380" checksum="5349D78968C40E67" modified="2007-05-15" version="1">MRRALEVAATATTAETFPNPRVGCVVVDAREDVVVGEGYHPKAGEPHAEVFALRAAGELARGATAYVTLEPCNHYGRTPPCARALVDAGVARVVVGFIDPDPRVSGGGIQTLLDAGIEVAVGCEEALCREINADFIARQVAARDAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWW2</accession>
    <name>A4RWW2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_7211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417893.1">
        <property type="nucleotide sequence ID" value="XM_001417856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWW2"/>
    <dbReference type="STRING" id="436017.A4RWW2"/>
    <dbReference type="GeneID" id="5002155"/>
    <dbReference type="Gramene" id="ABO96186">
        <property type="protein sequence ID" value="ABO96186"/>
        <property type="gene ID" value="OSTLU_7211"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7211"/>
    <dbReference type="eggNOG" id="KOG3035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051989_0_2_1"/>
    <dbReference type="OMA" id="DSHTQKG"/>
    <dbReference type="OrthoDB" id="671439at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd01838">
        <property type="entry name" value="Isoamyl_acetate_hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="230" mass="25567" checksum="40DD669FFE7E5415" modified="2007-05-15" version="1" fragment="single">RESVVLFGDSLTERSFEDGGFGARVQHEFRRFADVRCRGYSGYNTEHALCLLDEVFPLNEDVDDDGAFATYKRAPVLVTILFGSNDACAKNSSAGDVQHVPLPRYEQNLKTIVERVRRMQPSPRILFITPPPVDDEAWLRDCATRAAQPGLGFGSLLNDTAPNRTNAGVKPYAEAMKRVARFYDIPVVDLHAALEFSNGEVDETQFCDGLHFSEAGQRQVASLVIDALRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWX0</accession>
    <name>A4RWX0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_15267</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417898.1">
        <property type="nucleotide sequence ID" value="XM_001417861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWX0"/>
    <dbReference type="STRING" id="436017.A4RWX0"/>
    <dbReference type="MEROPS" id="C97.A01"/>
    <dbReference type="GeneID" id="5002092"/>
    <dbReference type="Gramene" id="ABO96191">
        <property type="protein sequence ID" value="ABO96191"/>
        <property type="gene ID" value="OSTLU_15267"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15267"/>
    <dbReference type="eggNOG" id="KOG0324">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060642_1_0_1"/>
    <dbReference type="OMA" id="FADHHER"/>
    <dbReference type="OrthoDB" id="21221at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070646">
        <property type="term" value="P:protein modification by small protein removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF7">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="167" mass="17933" checksum="763A9A452163853B" modified="2007-05-15" version="1">MFRDFLREVQPRYTSETYNLLRHNCNNFTSEAAMFLVGKDIPQQILDLPDVFLSTEIGQALGPMLGMFEQRMRHTSGTSALGECLAPGAVEDAVPKKIAGLPDLGAKPRKQKATANSASASSEDIAKMVRSISQTFGELKDSGASTQQATAAALLAAKDELAAKSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX91</accession>
    <name>A4RX91_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">fructose-bisphosphatase</fullName>
            <ecNumber evidence="3">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_15350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FBPase class 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="3"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417955.1">
        <property type="nucleotide sequence ID" value="XM_001417918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX91"/>
    <dbReference type="STRING" id="436017.A4RX91"/>
    <dbReference type="GeneID" id="5001821"/>
    <dbReference type="Gramene" id="ABO96248">
        <property type="protein sequence ID" value="ABO96248"/>
        <property type="gene ID" value="OSTLU_15350"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15350"/>
    <dbReference type="eggNOG" id="KOG1458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039977_2_2_1"/>
    <dbReference type="OMA" id="ENDEPTW"/>
    <dbReference type="OrthoDB" id="541375at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF12">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="8">
        <location>
            <begin position="20"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="9">
        <location>
            <begin position="160"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="32735" checksum="4BF7CF3346E63C94" modified="2007-05-15" version="1">MVVLISRRGAKSLIRGLERRGGSNASGDSQQKLDVVANDIFKRHLTECGGVKYYASEEDDTPVVLNVDGGYVVCIDPLDGSRNIACNVPVGSIFGVYRAIEGASAEENAVQPGREQVAAGYAHYSGATTLVLACGDEGPAVEYTLFDGEFAVANKRMSCPPRGQVYSLNDARFDDWPEGLKSYINDIRNGRGESGSQYSARYICSLVGDAHRTLIYGGWCGNPRPHLRVVFEAAPLAFVARAAGAASSDGIRCSDEATNGVETILDKKPTTLHERSPLFLGSCEDIAELVLRGDVRQDGSKTYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXD6</accession>
    <name>A4RXD6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417732.1">
        <property type="nucleotide sequence ID" value="XM_001417695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXD6"/>
    <dbReference type="GeneID" id="5001914"/>
    <dbReference type="Gramene" id="ABO96025">
        <property type="protein sequence ID" value="ABO96025"/>
        <property type="gene ID" value="OSTLU_31657"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31657"/>
    <dbReference type="HOGENOM" id="CLU_1143912_0_0_1"/>
    <dbReference type="OMA" id="ACPKTFP"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="26342" checksum="D10C52B725A2EE27" modified="2007-05-15" version="1">MYHYVDPQGREQGPFAYAHLAKWFKAGYLRPNLGCRRQDETTYARTVTQALLEDGAMHGVPEHMLGEVVRPTTAARTGGGGATTVNVPPPPATTATTSVGRSEEDVAECMERLMMVLDHVLAIVLEGGLRAEFGEVWMDMLHTPPPWTLETTLRELKANWGSLFSTQPRRMREIEVLLDAAIRQRKNQPIAAGGLARDVSSAAVALLNACPKTFPPEVIEHLRVAWEECEKIRAHLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXF6</accession>
    <name>A4RXF6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DEAD/DEAH box helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_24549</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417991.1">
        <property type="nucleotide sequence ID" value="XM_001417954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXF6"/>
    <dbReference type="STRING" id="436017.A4RXF6"/>
    <dbReference type="GeneID" id="5001835"/>
    <dbReference type="Gramene" id="ABO96284">
        <property type="protein sequence ID" value="ABO96284"/>
        <property type="gene ID" value="OSTLU_24549"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24549"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_3_1"/>
    <dbReference type="OMA" id="NEICITA"/>
    <dbReference type="OrthoDB" id="4255at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="32"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="190"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="38133" checksum="CA904FD96E7AC82D" modified="2007-05-15" version="1">MDVGNFGMSAITVAALRKRGVDTLFPIQQAVLKPALSGEDVVGRARTGTGKTLAFALPVIERLLTDGTSGRSRNPKCIVLAPTRELAKQVENEICITAPSLETVCVYGGTPIGQQEGKLRRGVDIVVGTPGRVQDLMNRRSLDLGEIEFVVLDEADQMLNVGFEEDVEAILQDCPESRQTFLFSATMPSWVKQITKKFLKPGHVVVDLDKKAICFTQTKRAADELTAALGRRVASEVLHGDIAQAQRERTLQRFRDNRFSVLIATDVAARGLDISDVDLVIHYELPNDVESFVHRCGRTGRAGQLGAAIAMHTDRESYMIRRIKKETGCEFRTIGIPSSTETRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXH2</accession>
    <name>A4RXH2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic peptide chain release factor subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_49593</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Modulates plant growth and development.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of two subunits, one of which binds GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic release factor 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417750.1">
        <property type="nucleotide sequence ID" value="XM_001417713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXH2"/>
    <dbReference type="STRING" id="436017.A4RXH2"/>
    <dbReference type="GeneID" id="5001823"/>
    <dbReference type="Gramene" id="ABO96043">
        <property type="protein sequence ID" value="ABO96043"/>
        <property type="gene ID" value="OSTLU_49593"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49593"/>
    <dbReference type="eggNOG" id="KOG0688">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035759_2_1_1"/>
    <dbReference type="OMA" id="GPGTEKM"/>
    <dbReference type="OrthoDB" id="10254527at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.960.10:FF:000002">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000006">
        <property type="entry name" value="Peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.60:FF:000003">
        <property type="entry name" value="Peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.960.10">
        <property type="entry name" value="eRF1 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="entry name" value="eRF1 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024049">
        <property type="entry name" value="eRF1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_Pelota-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004403">
        <property type="entry name" value="Peptide_chain-rel_eRF1/aRF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03676">
        <property type="entry name" value="aRF1_eRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10113">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03463">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55481">
        <property type="entry name" value="N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1/Pelota-like N-terminal" evidence="8">
        <location>
            <begin position="4"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="442" mass="49227" checksum="007DB2CBBCCC1E36" modified="2007-05-15" version="1">MADQDSNEKEIEIWKMRKLIKKLEDARGNGTSMISLVIPPKGQVNLVQKMLIEEMGTATNIKSRVNRQSVLDAIGSAQQRLKLYNKVPPNGLVVYCGAVLTESGKERQMKIDFEPFKPINTSLYMCDNKFHTAALSDLLQNDQKYGFVVMDGNGTLFGTLCGNHREILQKISVDLPKKHGRGGQSALRFARLRLEKRQNYLTKVAELTTQHFISNDRPNVAGLVLAGSADFKNKLAEADCFDSRLQEVTLAVVDVSYGGENGFNQAIELSADTLSSLKFIQEKKLVGKFFDEIAQDTGKYVFGINDTLTCLEMGAVETLVCWEDLEVARVTLKNSSTGEETIKFLRPEETEGNENDHVRDADGNDLEIVESVPLLEWLANEYKKFGCVLELISDKSQEGNQFCRGFGGIGGLLRYQVDLTAFEVAADANSDDWDSDDSECFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXL1</accession>
    <name>A4RXL1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417772.1">
        <property type="nucleotide sequence ID" value="XM_001417735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXL1"/>
    <dbReference type="GeneID" id="5001862"/>
    <dbReference type="Gramene" id="ABO96065">
        <property type="protein sequence ID" value="ABO96065"/>
        <property type="gene ID" value="OSTLU_31733"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31733"/>
    <dbReference type="HOGENOM" id="CLU_651151_0_0_1"/>
    <dbReference type="OMA" id="VATHWPL"/>
    <dbReference type="OrthoDB" id="10377490at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="422" mass="46602" checksum="BA52639E4BE54B82" modified="2007-05-15" version="1">MGGRRAHHENGDHPMCSFAACVPPKEWSAERVRTCVDECFEKLPKTYYKVERRECGGLARSMTHKVKFASGNSYELALVSDTLGAEEVGKKFEAIREEHADLRERSLALKAYLKELSGKHKFSFVVIDDTTKRVFAAATQFSAPLSFGHSKDGMLVLFCGAGGKSVATHWPLNEQEVTQCAQHGEAARRRSIDVRDRPPANAAGGSRRSVDGGRRSVDGGRRSVDGGRRSIDEKAVFTSEVGWVDPGATVPVDFTHNRIVLTHLPVGRFVYGHGYLQPYEFTSFWSSAQSNRAGVPERAFHSGNDWSKESPNSSRRSSFDVNSADGAPRRSSIDERHRKWESTNSKCDTEASWKKPAAEAKRPLPPRSPIKSQEPIVPSLEKLSVKDGEKKKSSLGSKIRRNLSVESLKKAFGVAGKKSEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXM2</accession>
    <name>A4RXM2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_38463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417779.1">
        <property type="nucleotide sequence ID" value="XM_001417742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXM2"/>
    <dbReference type="GeneID" id="5001869"/>
    <dbReference type="Gramene" id="ABO96072">
        <property type="protein sequence ID" value="ABO96072"/>
        <property type="gene ID" value="OSTLU_38463"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38463"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_2_1"/>
    <dbReference type="OMA" id="CAFISHD"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37531" checksum="BA167E89F10DEE92" modified="2007-05-15" version="1">MLFDVFARVRCRLDILNDILLQRYHCKHLPSRAEDVIVDDLRGKTCVVTGPTSGIGVTTARALVKRGARVVLACRTPSKAEALVERWTKEAAAVGTAPPDCAVMALDLDSLASVEAFAKAFQQREKRLDVLINNAGIFDMSGAYVRTSDGREQHLQANFLAPALLTMTLLNALRKTGAETGDARVVFVSSKLHELCTGLNLSDMDFKRSSYSSQAAYASSKLAEVLFVKALDARLRAKAPGTRALVLHPGNIVTGVVRTLPMWLQSLYKILFERILLTADQGARCSLYCATRTEAVASATIGPYFTSECEERTPSKYALVEGEAEKLWRYTLKELGLEDDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY46</accession>
    <name>A4RY46_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_9611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418105.1">
        <property type="nucleotide sequence ID" value="XM_001418068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY46"/>
    <dbReference type="STRING" id="436017.A4RY46"/>
    <dbReference type="GeneID" id="5001878"/>
    <dbReference type="Gramene" id="ABO96398">
        <property type="protein sequence ID" value="ABO96398"/>
        <property type="gene ID" value="OSTLU_9611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9611"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_18_1_1"/>
    <dbReference type="OMA" id="RREAMRW"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44743:SF10">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44743">
        <property type="entry name" value="PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="78" mass="8782" checksum="547B931FC595CAA9" modified="2007-05-15" version="1" fragment="single">EDGNARRRGKFYDILGVKPGADVRAVKSAYRKLAAVWHPDKWTRASPEDAAKAEATFKSVQRAYATLSDAKQRKLYDL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-10-05" modified="2025-06-18" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYD2</accession>
    <name>PURA_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Adenylosuccinate synthetase, chloroplastic</fullName>
            <shortName evidence="2">AMPSase</shortName>
            <shortName evidence="2">AdSS</shortName>
            <ecNumber evidence="2">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PURA</name>
        <name type="ORF">OSTLU_19549</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">This protein may be expected to contain an N-terminal transit peptide but none has been predicted.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="2"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418148.1">
        <property type="nucleotide sequence ID" value="XM_001418111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYD2"/>
    <dbReference type="SMR" id="A4RYD2"/>
    <dbReference type="STRING" id="436017.A4RYD2"/>
    <dbReference type="EnsemblPlants" id="ABO96441">
        <property type="protein sequence ID" value="ABO96441"/>
        <property type="gene ID" value="OSTLU_19549"/>
    </dbReference>
    <dbReference type="GeneID" id="5002244"/>
    <dbReference type="Gramene" id="ABO96441">
        <property type="protein sequence ID" value="ABO96441"/>
        <property type="gene ID" value="OSTLU_19549"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19549"/>
    <dbReference type="eggNOG" id="KOG1355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029848_0_0_1"/>
    <dbReference type="OMA" id="FHHAKPI"/>
    <dbReference type="OrthoDB" id="10265645at2759"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046040">
        <property type="term" value="P:IMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.170.10:FF:000001">
        <property type="entry name" value="Adenylosuccinate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.300.10:FF:000002">
        <property type="entry name" value="Adenylosuccinate synthetase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002223">
        <property type="entry name" value="PRK01117.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="ADENYLOSUCCINATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846:SF0">
        <property type="entry name" value="ADENYLOSUCCINATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0150">Chloroplast</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0934">Plastid</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000399279" description="Adenylosuccinate synthetase, chloroplastic">
        <location>
            <begin position="1"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="17"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="2">
        <location>
            <begin position="18"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="2">
        <location>
            <begin position="43"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="45"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="2">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="2">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="2">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="301"/>
            <end position="307"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="2">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="333"/>
            <end position="335"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="416"/>
            <end position="418"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03125"/>
        </source>
    </evidence>
    <sequence length="428" mass="46651" checksum="8DCB750CF7135875" modified="2007-05-15" version="1">MRGREDANARVLGSQWGDEGKGKLVDILAREYDVVARCQGGANAGHTIYDDDGKKYALHLVPSGILNENATCVVGNGVVVHLPGMFDEIDALLKAGVDARGRMMVSDRAHLLFDLHKEIDGLREAELSGNKIGTTKRGIGPAYASKATRNGVRLGDIRDADKFANALRTLAADAAARFDGFEYDVEAEIVRYREIASRIEPFIADTVEYVNDAHRNGKKILVEGANATMLDLDFGTYPFVTSSNPAIGGVSNGLGLAPRKFETIIGVAKAYTTRVGAGPYPTELFGDVADKLRELGYEYGTTTGRPRRIGWLDMVALNYANQINGFTHLNITKLDVLSEMDELKIGVAYELPNGKTTTAFPADIATLENVKVVYETLPGWKTDIANVRSWDDMPENAKKYILRCEELSGVECRYIGVGPGRDAMVIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYG9</accession>
    <name>A4RYG9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nitric oxide synthase-interacting protein zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_87446</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418387.1">
        <property type="nucleotide sequence ID" value="XM_001418350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYG9"/>
    <dbReference type="STRING" id="436017.A4RYG9"/>
    <dbReference type="GeneID" id="5002262"/>
    <dbReference type="Gramene" id="ABO96680">
        <property type="protein sequence ID" value="ABO96680"/>
        <property type="gene ID" value="OSTLU_87446"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87446"/>
    <dbReference type="eggNOG" id="KOG3039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053742_0_0_1"/>
    <dbReference type="OMA" id="PCVTKFM"/>
    <dbReference type="OrthoDB" id="116827at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031790">
        <property type="entry name" value="Znf-NOSIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15906">
        <property type="entry name" value="zf-NOSIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitric oxide synthase-interacting protein zinc-finger" evidence="4">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="33867" checksum="59CC5F9AD1D2C284" modified="2007-05-15" version="1">MARGSTKKHSKQAGTLGSEALTHAERRALGYGTVRERLGRETVKDFDACALTLSTTDDGVCTPRGVVYDRGAIVQCLVDQRREFERKAREHARAKEAEARADDARDAKRRRVELAAFHAANHGGGGTTDEVEGEGKAYAGAASRQAMEVNATRAATMDGFWRVDGGVDDGLTRAKEKPEKETKCPTTLERLRMKDLVTIKWTKVREGESGKYMCPITYKTFTNATAIVVLKPTGTAISEEGFKRVVEKEGAYDGVKIRPDKDVIKLQKGGTGFAASGTQVESKANFDMGLAGGAELRGQSRGGQSKFGLRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYR2</accession>
    <name>A4RYR2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">E3 ubiquitin-protein ligase CHFR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_92878</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CHFR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418208.1">
        <property type="nucleotide sequence ID" value="XM_001418171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYR2"/>
    <dbReference type="STRING" id="436017.A4RYR2"/>
    <dbReference type="GeneID" id="5002230"/>
    <dbReference type="Gramene" id="ABO96501">
        <property type="protein sequence ID" value="ABO96501"/>
        <property type="gene ID" value="OSTLU_92878"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92878"/>
    <dbReference type="eggNOG" id="ENOG502RRFT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_647930_0_0_1"/>
    <dbReference type="OMA" id="CAKRYFG"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="68"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="303"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="244"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="424" mass="46287" checksum="2D66160C63B50F0D" modified="2007-05-15" version="1">MSRARGVCALVLIDDGAATTRDADVPEEIILQRLRASSEDDDGASDDDGDDDDGVPGILSPPSARDVVVIGRQKGVVDHAMDCASIPLLLSRKHAAMTCDGAAHYVRDLATTNGTFVNGSRIDAKVDVALKDGDVVAFGGPRYVARDSGRLANPFRYRYVRLERPGVDARSKRLRASQENDAAREAFGSQGAQLSQVYQAVQASQTSESYEELDDMLKARLRSMFDGEVDFAQACAKRYFGVATPTASPSKSTGKRKSVGQATRSAPSSQDPDADDGLRDKLSELVLERLRDRPAWVESELKCAICREWMTLPHALITCGHLFCLECIDNSFCHAYTCPCCRSRPNAPRELLFTPSALADRLLDKYVIPTLTTKELLDRKAKEQNAVQARKKRVKRAAEVSMRVGTLSTVSVQETQSATPRSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYX2</accession>
    <name>A4RYX2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translocation and assembly module TamB C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_40935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418236.1">
        <property type="nucleotide sequence ID" value="XM_001418199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYX2"/>
    <dbReference type="STRING" id="436017.A4RYX2"/>
    <dbReference type="GeneID" id="5002336"/>
    <dbReference type="Gramene" id="ABO96529">
        <property type="protein sequence ID" value="ABO96529"/>
        <property type="gene ID" value="OSTLU_40935"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40935"/>
    <dbReference type="eggNOG" id="ENOG502QTMX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006278_0_0_1"/>
    <dbReference type="OMA" id="NTLYADH"/>
    <dbReference type="OrthoDB" id="1386367at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053022">
        <property type="entry name" value="Chloroplast_translocon_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34457">
        <property type="entry name" value="EMBRYO DEFECTIVE 2410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34457:SF3">
        <property type="entry name" value="PROTEIN TIC236, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Translocation and assembly module TamB C-terminal" evidence="6">
        <location>
            <begin position="520"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="926" mass="99642" checksum="76A99DB5A6609BF3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ49</accession>
    <name>A4RZ49_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418513.1">
        <property type="nucleotide sequence ID" value="XM_001418476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ49"/>
    <dbReference type="GeneID" id="5002478"/>
    <dbReference type="Gramene" id="ABO96806">
        <property type="protein sequence ID" value="ABO96806"/>
        <property type="gene ID" value="OSTLU_92919"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92919"/>
    <dbReference type="HOGENOM" id="CLU_777050_0_0_1"/>
    <dbReference type="OMA" id="MLRATTH"/>
    <dbReference type="OrthoDB" id="10614025at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="357" mass="38096" checksum="86D916CA923BB4DA" modified="2007-05-15" version="1">MSKSDEDGSSRLAPTRAKRALFPSTTASPRANAPISPVEQASRMLRATTHRTFASSALASPPSPRDEAATNTTPTKTTPDFAATTPMSKHVRTLVKNAMTSLTKGRSRLEELVKSHGRGLNFSDAGAAESPVVRKSAPSPTVSATTSSLDREAAREATEMLLRSAKKLATPKKALRSPLRSPAPVQMDRVVPGVPMSILADSTATESMLVQENQVMTDDAACDEEVTSQPSLPPGFDASAMLNDEDAATAAAPVSLTDDIVSHIDVFARMMGKVISDTIEEISASLDVVPVTEIPERRTNVTEPTTPSRRSSRRKSVVVNNEKSAVDPTTPSRRSGRSKDPVTPSRRSKRVASRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZF2</accession>
    <name>A4RZF2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_5113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418319.1">
        <property type="nucleotide sequence ID" value="XM_001418282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZF2"/>
    <dbReference type="STRING" id="436017.A4RZF2"/>
    <dbReference type="GeneID" id="5002456"/>
    <dbReference type="KEGG" id="olu:OSTLU_5113"/>
    <dbReference type="eggNOG" id="KOG1552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_5_4_1"/>
    <dbReference type="OMA" id="AGHNNCE"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="87"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="276" mass="29985" checksum="AD570CEB24718271" modified="2007-05-15" version="1" fragment="single">LARDLAFFPPEPPSYALGEREASDDGDGERAGTSDTFQRVLDDFRVDLVTTARGNEVVAMTCEAPPTRISAASEDDARAMQDGANLTLIYSHGNAVDAGEVAPFARKLSQQLNCRVVTYDYSGYGQSRGEPSVADTYADIDAVVAHVIERFGVSREEIILLGQSIGSGPTCFHAGKRENAGFGAVVLVSPLLSALNVVSSPQAWCTPAKVFRKMDVYKNYQVVKNIQCPILLIHGDQDNVVHVSHGETLWETIRKSAKTNESLLEPYWIRGAGHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZZ7</accession>
    <name>A4RZZ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418656.1">
        <property type="nucleotide sequence ID" value="XM_001418619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZZ7"/>
    <dbReference type="STRING" id="436017.A4RZZ7"/>
    <dbReference type="GeneID" id="5002867"/>
    <dbReference type="Gramene" id="ABO96949">
        <property type="protein sequence ID" value="ABO96949"/>
        <property type="gene ID" value="OSTLU_93006"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93006"/>
    <dbReference type="HOGENOM" id="CLU_038991_0_0_1"/>
    <dbReference type="OMA" id="NISFNAC"/>
    <dbReference type="OrthoDB" id="512207at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="2">
        <location>
            <begin position="24"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="39269" checksum="FDD4B4D401CFD635" modified="2007-05-15" version="1">MTSAREVARARLARLARVVRAPARDVVVFGGVVVDVHARARGATARGTSARGRVDRGVGGVGLNVACACAATSAARVRLVSACGDDADGASVREAWRARARGRDDGAGVRARAGARTGRVVAVTDESGEIVASVADVDVVERDVDEEWCEKYASDARGARVVVIDGNLSARGIRAARRAAATTATWFEPVSVAKAVRIVESGDAGRPMVGVRWCSPNAAELRELANAVRRSWAKGSPMSPCPFNPELEFDAANDALDALASDIATVLAAGCERVVLTLGSLGVIVSSAPDGDASNAEHAHVPAFAVKSAASLIGAGDALVGGAVGALARGVDEMRAIAIGVACASMACERREAALFDVDAREIDRRAAIVFDGITPIKAAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S015</accession>
    <name>A4S015_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_24784</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418895.1">
        <property type="nucleotide sequence ID" value="XM_001418858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S015"/>
    <dbReference type="GeneID" id="5002982"/>
    <dbReference type="Gramene" id="ABO97188">
        <property type="protein sequence ID" value="ABO97188"/>
        <property type="gene ID" value="OSTLU_24784"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24784"/>
    <dbReference type="eggNOG" id="KOG1591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_817212_0_0_1"/>
    <dbReference type="OMA" id="EKWIARI"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF226">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="215"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="347" mass="36698" checksum="A1184F4C6635D911" modified="2007-05-15" version="1">MTTSAPRLAASLCERRASTPASTSSRVPARTRRGAPPRAGFGAAVPTARSAAVLDKHVPIDRYADGLRQLHASPDVFVVDDFLSADACADIIARAKAKGDMTQSPVVYAGWTNDVEAWTSTVSSGPAVWIGALAMLIGSAAFGQSGLGLLGEGVVGYLGAVGAAYAASLAYVKDKERELGDLRTSTSTALDGSGVGERELIRATERLLPGTSWTTYEAPTVIRYERGQKLAPHFDANRGAAVEDANRGGQTLVTLLVYLNDVDEVRGGGQTVFGRLGDLAVRPAKGRALVFFPANADGEFDDRVEHEGTEANEEKWIVRIWVHQNEVGGPPSGLPDDWNDERGVVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S059</accession>
    <name>A4S059_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-amylase</fullName>
            <ecNumber evidence="3">3.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">1,4-alpha-D-glucan glucanohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_35756</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418686.1">
        <property type="nucleotide sequence ID" value="XM_001418649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S059"/>
    <dbReference type="STRING" id="436017.A4S059"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="GeneID" id="5002760"/>
    <dbReference type="Gramene" id="ABO96979">
        <property type="protein sequence ID" value="ABO96979"/>
        <property type="gene ID" value="OSTLU_35756"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35756"/>
    <dbReference type="eggNOG" id="KOG0471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030069_1_0_1"/>
    <dbReference type="OMA" id="MQYFEWN"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11314">
        <property type="entry name" value="AmyAc_arch_bac_plant_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012850">
        <property type="entry name" value="A-amylase_bs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07821">
        <property type="entry name" value="Alpha-amyl_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00810">
        <property type="entry name" value="Alpha-amyl_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="7">
        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-amylase C-terminal beta-sheet" evidence="8">
        <location>
            <begin position="352"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="410" mass="46240" checksum="91687CBDE775A29D" modified="2007-05-15" version="1">MQKEIVKESGVLPRIATGREIMIQGFHWESHNLDWYKIVQDRLGEMNQAGFTQVWLPPPADSLAPQGYLPRNMYSLNSAYGSEQALRNLIANCKEHDVLPVLDAVLNHRCATHQGAGGKWNRWEGTGMDWGEWAIDNRNPDFAGQGNHPTGDEFSGAPNIDHTNERVRSDLAKWFQWLRNDIGFGGVRFDFSKGYGGQFAGEYIKAMDPEFAVGEYWDTLAYGAGLEYNQDAHRQRIVDWIDAAGGNCTAFDFTTKGILQEACGRSEFWRLIDSEGRAPGVIGLWPARAVTFIDNHDTGSTQGHWPFPNDKVAMGYAYILTHPGTPCVMWDHYFDWGEKLSNNIKTLMEARQSCGIHSRSKLQIIAANDGLYAAIVDNRMAVKLGRDHWSPAGDDWTHICGDNDWSVWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0C0</accession>
    <name>A4S0C0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rubisco LSMT substrate-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32687</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418946.1">
        <property type="nucleotide sequence ID" value="XM_001418909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0C0"/>
    <dbReference type="STRING" id="436017.A4S0C0"/>
    <dbReference type="GeneID" id="5003036"/>
    <dbReference type="Gramene" id="ABO97239">
        <property type="protein sequence ID" value="ABO97239"/>
        <property type="gene ID" value="OSTLU_32687"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32687"/>
    <dbReference type="eggNOG" id="ENOG502QV24">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_768132_0_0_1"/>
    <dbReference type="OrthoDB" id="498498at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="38636" checksum="DC703E473296915B" modified="2007-05-15" version="1">MFSKDEDDRELAVVLWLLFATRAGGDIWEAYAAWLPTAANGLPSTLLATDEELASTQNEALVRRAREVRSLVSLAFDRVPFGAVPGKLTPDDLRWGYALVTSRAIAAEVGADEEGGADDTQVAVLAPCVDMANHVDIANVTALKKIGASDGGGLKGAYWRVVTGGSVDGGGGACCLETNRPIQGADEEVTISYQPDASNDELMESYGFSLRGNRNDRLGGANITLRLGAFRQAMEESGVLGGSTPEEDVRRIIAVTASACGGIPPGRELVADDDWTLEGDDIQRELDDAVKLGEAWERELDAFATTLEEDEAELLENRKYTTAFGRAAVEYRAERKRLLGVGLGALSAYVDWLCADDDVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0D9</accession>
    <name>A4S0D9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418728.1">
        <property type="nucleotide sequence ID" value="XM_001418691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0D9"/>
    <dbReference type="STRING" id="436017.A4S0D9"/>
    <dbReference type="GeneID" id="5002896"/>
    <dbReference type="KEGG" id="olu:OSTLU_93044"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_944570_0_0_1"/>
    <dbReference type="OrthoDB" id="2019724at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47623">
        <property type="entry name" value="OS09G0287300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47623:SF1">
        <property type="entry name" value="OS09G0287300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="295" mass="32749" checksum="31A5AA7CCEB24BE4" modified="2007-05-15" version="1" fragment="single">LRHAKSDWSDDTLPDKRRPLAAKGRRRAMRCATRLDERAWTPDLILTSDATRCLETLEAMGDAVEAFRTAPVILVPDFYDKTHGDEGDVSQAKSAKVIGKRVGVEVGLGTMQPRTVMCVGHNFGFELAARSFCGSANVELKTAHAALLTARGPARRGERAFKVIVAPLDDTALAFEVWNRELRGSTSVMFCVCDVAVCAVIDDAPPERNHHDDAWQRAFTDHKFRLEAVLNPEEPESASEIIKRVVERMIEELIDSDMSSEEVLERVIAQAESVEDAMSHQSRALGSGDFEIEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0J5</accession>
    <name>A4S0J5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418752.1">
        <property type="nucleotide sequence ID" value="XM_001418715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0J5"/>
    <dbReference type="GeneID" id="5002828"/>
    <dbReference type="Gramene" id="ABO97045">
        <property type="protein sequence ID" value="ABO97045"/>
        <property type="gene ID" value="OSTLU_32767"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32767"/>
    <dbReference type="HOGENOM" id="CLU_922543_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="302" mass="32354" checksum="178BA058D6A3C2C2" modified="2007-05-15" version="1">MGEDAKTETAYGAIARDVDVEATPLEGERARRETLAAKVRGRKTLGLAAVALAGVGAVARARAPEMFTASLGRAPLVPALGLADGAYYARGGKHRLRDPFLNGVPMKQMTDAQKSANVVNWCRFRNVASNGNFRCGVTCRQDGENGSNAPEVFYIGSTPADDDGNVYRTISRKGEDGNMYVCYSDWSQNNGWNRKVMKCPTSGSRAVLTNSTSLPEGAKLTISEVPAAKKHTQNVEYDMGTLYTFVNKDLASRESGKGLCRDFGSSIACHARQNNIADVNAQFEFIPVVPDDASGDVSACPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S107</accession>
    <name>A4S107_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_1114</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419069.1">
        <property type="nucleotide sequence ID" value="XM_001419032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S107"/>
    <dbReference type="STRING" id="436017.A4S107"/>
    <dbReference type="GeneID" id="5003334"/>
    <dbReference type="Gramene" id="ABO97362">
        <property type="protein sequence ID" value="ABO97362"/>
        <property type="gene ID" value="OSTLU_1114"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1114"/>
    <dbReference type="eggNOG" id="KOG0339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="HIEACAP"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="86"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="294"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="444"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="478" mass="51770" checksum="2AD6D082D40B2042" modified="2007-05-15" version="1" fragment="single">DSLREVDHAREEYEKFERVTYVAPKELADVDVGAARAAADARASGGAEDVAPISRFGQGGALDVDCLRALRRMGYESPTAVQAQCLPVIWSGHDALVMAKTGSGKTLAFLLPAYAQISRQRPLTKREGPIALVLAPTRELASQIANEAHKFTKFGVSGARCCAIFGGVSKRDQFKKLRAGAEIVVATPGRLVDVLCMKNSTNLRRVTYLALDEADRMLDMGFEKIVRSICQAVRPDRQCVMFSATMPAAMQRLARDVLARDAVTVSIGNVGGANEDVRQVVYVFEDDARRAAWLFENLGDAVDEGQAIVFVNHKSSVEELVNELATRGIKAVALHGDLDQAQRQFAMKAFKSEHAHVLVATDVAARGLDVEAIKTVVNFHPARDMSTHVHRIGRTGRAGALDGRAYTLFTARDSAKFAQQLEQNLEAAGQPVPLDLKALARGTYNKRPRSDHGGDAPRHGKVGGRGLGFTSHHRPSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S149</accession>
    <name>A4S149_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419092.1">
        <property type="nucleotide sequence ID" value="XM_001419055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S149"/>
    <dbReference type="GeneID" id="5003353"/>
    <dbReference type="Gramene" id="ABO97385">
        <property type="protein sequence ID" value="ABO97385"/>
        <property type="gene ID" value="OSTLU_32973"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32973"/>
    <dbReference type="HOGENOM" id="CLU_553651_0_0_1"/>
    <dbReference type="OMA" id="PVVHERQ"/>
    <dbReference type="OrthoDB" id="10660534at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="480"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="493" mass="54343" checksum="989EA5F2CCDD48AB" modified="2007-05-15" version="1">MPNACAPCCGSKPKGVGDDESDDAGAPAPNSLRHVSATKTKRTAPKSLRNLVQYGAGDERDASDDSGAEKVEDDPRAQYETATTPAGKPKFDPNKFKKRVGDHLAAKRALEAERRPLLEETTARVGVEPEDEKSERRAKREERERRKEAKRAAKEDKQKQRARVLKARSTQRRCWWILMIVVLVVIVCAGIIFGDDVHFNYWRSNADRVDARDDSTQTHAIDSNQMDERPTTTEDSTDVSRAGLSLADGPKSQDSFDDDGDDGDDSDEHARALDVDGDEYGVDFNDPSLRTMAPKAWRRREREIEKIKRRARSSAKDDVQRFVEGAHRELGVRDEEKDAEEEYEDTLIERIESSPGVVIEKRRGGEDASRSGDKAAEVLAKSQASILSHGLIRDTKSSSRDLDRLSFGDDVAAGGTASPDSRAAAAGEAPTAREASKTKRAADIKDDDSDPDFGLSAVFRPPNEPVVHERQPDDDGAFSAALPRRVPRRALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1I8</accession>
    <name>A4S1I8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">CCE9901</strain>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="200" mass="21946" checksum="BADA21301EBC9E8F" modified="2007-05-15" version="1">MASDGRGAAITQAKLVLLGDMGAGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCADDRTIKFEIWDTAGQERYHSLAPMYYRGAAAAIIVYDIQSQSSFARAKSWVRELQKQGNAALVMALAGNKCDMEEKREVEREEAEAYASENGLFFMETSAKEALNVTELFHEIAVKLPKAPTPTNGPGVVLTNQNRTPQKSQCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
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        <name evidence="6" type="ORF">OSTLU_88041</name>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_88041"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_446462_0_0_1"/>
    <dbReference type="OMA" id="HVPSMMS"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
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        <location>
            <begin position="20"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="629" mass="68773" checksum="FE02FBA3053C9975" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Z2</accession>
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        <submittedName>
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        </submittedName>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419413.1"/>
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    <dbReference type="KEGG" id="olu:OSTLU_93180"/>
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    <dbReference type="OMA" id="CAHARIM"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="500"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="680" mass="75563" checksum="5CD34860DD183850" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S282</accession>
    <name>A4S282_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_16663</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419704.1">
        <property type="nucleotide sequence ID" value="XM_001419667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S282"/>
    <dbReference type="GeneID" id="5003642"/>
    <dbReference type="Gramene" id="ABO97997">
        <property type="protein sequence ID" value="ABO97997"/>
        <property type="gene ID" value="OSTLU_16663"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16663"/>
    <dbReference type="eggNOG" id="KOG4308">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_291417_0_0_1"/>
    <dbReference type="OrthoDB" id="504976at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase" evidence="3">
        <location>
            <begin position="137"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1048" mass="115136" checksum="8C360175B9D9CA25" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2K2</accession>
    <name>A4S2K2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfatase-modifying factor enzyme-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419545.1">
        <property type="nucleotide sequence ID" value="XM_001419508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2K2"/>
    <dbReference type="STRING" id="436017.A4S2K2"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="GeneID" id="5003663"/>
    <dbReference type="Gramene" id="ABO97838">
        <property type="protein sequence ID" value="ABO97838"/>
        <property type="gene ID" value="OSTLU_94690"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94690"/>
    <dbReference type="eggNOG" id="ENOG502QS9T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_345272_0_0_1"/>
    <dbReference type="OMA" id="GACETYL"/>
    <dbReference type="OrthoDB" id="659at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="entry name" value="paralog of FGE (formylglycine-generating enzyme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051043">
        <property type="entry name" value="Sulfatase_Mod_Factor_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23150:SF36">
        <property type="entry name" value="HERCYNINE OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23150">
        <property type="entry name" value="SULFATASE MODIFYING FACTOR 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="2">
        <location>
            <begin position="200"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="819" mass="90841" checksum="1F59EFC4F32A51CD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3A7</accession>
    <name>A4S3A7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_12940</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419886.1">
        <property type="nucleotide sequence ID" value="XM_001419849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3A7"/>
    <dbReference type="STRING" id="436017.A4S3A7"/>
    <dbReference type="GeneID" id="5004235"/>
    <dbReference type="Gramene" id="ABO98179">
        <property type="protein sequence ID" value="ABO98179"/>
        <property type="gene ID" value="OSTLU_12940"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12940"/>
    <dbReference type="eggNOG" id="KOG0715">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_0_1_1"/>
    <dbReference type="OMA" id="MATDYYA"/>
    <dbReference type="OrthoDB" id="10256793at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000005">
        <property type="entry name" value="Chaperone protein dnaJ 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000037">
        <property type="entry name" value="Chaperone protein dnaJ A6 chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000002">
        <property type="entry name" value="Molecular chaperone DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000009">
        <property type="entry name" value="Putative Mitochondrial DnaJ chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008035">
        <property type="entry name" value="PRK10767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF10">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ A6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="12">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="13">
        <location>
            <begin position="146"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="11">
        <location>
            <begin position="146"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO98179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="369" mass="39454" checksum="8F9DDB448AE55807" modified="2007-05-15" version="1">MAGRDYYDVLGVSRSADGKELKRAYRQLARKFHPDVNKEPDAEQKFKEISNAYEVLSDDQKKAIYDRFGEDGLKGGMGGMGGMGGMGGDPFSNPFDLFESFFGGGMGGGMGGMGGMGGQRQARNRPTQGDDERYDLEIDFLEAVFGVEKELDTMRLENCDKCSGSGVKAGTKPVTCGTCGGQGQVVATVRTPLGNFQQVTGCQACGGTGQSSTPCPACSGDGRVRRSKKIQLRVPPGVDKGSRLRVRGEGNAGRRGGPPGDLYVFINVRDDPELKRFENVNISSTATIPYTKAILGCTVKVRTVDGPVDLKIPPGVQPGSTLLMAKRGVPRLGNDSIRGDHYVTVKVTIPAKLGDDERALIEQLDAKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4J3</accession>
    <name>A4S4J3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_26429</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420447.1">
        <property type="nucleotide sequence ID" value="XM_001420410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4J3"/>
    <dbReference type="GeneID" id="5004344"/>
    <dbReference type="Gramene" id="ABO98740">
        <property type="protein sequence ID" value="ABO98740"/>
        <property type="gene ID" value="OSTLU_26429"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26429"/>
    <dbReference type="HOGENOM" id="CLU_716379_0_0_1"/>
    <dbReference type="OMA" id="MANRMAC"/>
    <dbReference type="OrthoDB" id="424610at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF5">
        <property type="entry name" value="FERULOYL ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673058" description="Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein" evidence="3">
        <location>
            <begin position="29"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="4">
        <location>
            <begin position="184"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="363" mass="40109" checksum="F7C720B97F60E491" modified="2007-05-15" version="1">MDFILRRSLLQMFLILTLLLTLCASCRAGDADFKAQLSTTVDVRALTSSRYDGSEARPLLVFLHGYCLSDDAQQTLKLESMRNVPAVRNRLGIARRRQQTLVQSGLREAALDRNWIYLAPRAPRTTRECVLCNLQESSPNSQDRLFGSWITGILARDSPEFECRAWDGSDAVALPEISATDDLDVKYILEVVAAAKKEFNVDEKRIYVVGIATGGFMASRLACEKPELFRGVVSLAGGTFSDASRCRPKSGETNVLLVHGTDDHTVPIDGGVNARGIPFPSADDSFSTLGKAMDCSNVVAKSMDTLPADGNSVEVRVAKAKYDRCENNVDVEQWKLNGVDHFIERETSEALFYDVVTWLNDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4R1</accession>
    <name>A4S4R1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MRPL4</name>
        <name evidence="6" type="ORF">OSTLU_17340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420312.1">
        <property type="nucleotide sequence ID" value="XM_001420275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4R1"/>
    <dbReference type="STRING" id="436017.A4S4R1"/>
    <dbReference type="GeneID" id="5004366"/>
    <dbReference type="Gramene" id="ABO98605">
        <property type="protein sequence ID" value="ABO98605"/>
        <property type="gene ID" value="OSTLU_17340"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17340"/>
    <dbReference type="eggNOG" id="KOG1624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_5_1_1"/>
    <dbReference type="OMA" id="WIENTDA"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_uL4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="224" mass="24360" checksum="A824A6AFEE892616" modified="2007-05-15" version="1">MRVRWTIAEGQGRGEDAVVPVYSFDGEARGSVELPGRIFDQPLRVDVAHRVVRWQRAKARKGLHKTKSRGEVAGSTRKVRPQKGSGRARVGNLKAPQMRGGGTAHGPVVRSHAHALPKKVRRMGLKVALSAKAAEGKLIVVDSFAGMEPKTRAMKATLERLTGDLGLAAGGDELVRMSARNLPHVEVLPQIGANVYSILRRRTLIVTKSGLEQLIARLDAPIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S514</accession>
    <name>A4S514_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_25262</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420530.1">
        <property type="nucleotide sequence ID" value="XM_001420493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S514"/>
    <dbReference type="GeneID" id="5004417"/>
    <dbReference type="Gramene" id="ABO98823">
        <property type="protein sequence ID" value="ABO98823"/>
        <property type="gene ID" value="OSTLU_25262"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25262"/>
    <dbReference type="HOGENOM" id="CLU_290598_0_0_1"/>
    <dbReference type="OMA" id="YIAYHEK"/>
    <dbReference type="OrthoDB" id="424712at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF53">
        <property type="entry name" value="ACYL_TRANSF_3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="697"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="732"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="75"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="972"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1062" mass="118787" checksum="06FD149F191F863A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S522</accession>
    <name>A4S522_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_88671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420368.1">
        <property type="nucleotide sequence ID" value="XM_001420331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S522"/>
    <dbReference type="STRING" id="436017.A4S522"/>
    <dbReference type="GeneID" id="5004429"/>
    <dbReference type="Gramene" id="ABO98661">
        <property type="protein sequence ID" value="ABO98661"/>
        <property type="gene ID" value="OSTLU_88671"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88671"/>
    <dbReference type="eggNOG" id="ENOG502S6AI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1091502_0_0_1"/>
    <dbReference type="OMA" id="MEIYPDP"/>
    <dbReference type="OrthoDB" id="2016221at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36334">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF2358)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36334:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF2358)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="255" mass="28393" checksum="A917B22939EA01A8" modified="2007-05-15" version="1">MIARLARSRVARASNGEGDEEFRASVDGLREPCDDFVCKSSPAVENTLKSLIKDINAARGTNRSAAPYSPDVTYDDGALRFAGSEKYKRYCSYIENNLRQVTTRVTEISMEGSLDVATVKWELNAVNDIGRVGVDVTATYKMNLITGRVLEHREQWVVNPARTDAQAGALLESTRKAHALPLNAMEVADEAKKKFREISKSFASEDDQENSNIYVDPNDPMKFFQQDDTSKTDLLQLSLVAAVIYLLTKVFQVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S557</accession>
    <name>A4S557_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_43913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420385.1">
        <property type="nucleotide sequence ID" value="XM_001420348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S557"/>
    <dbReference type="STRING" id="436017.A4S557"/>
    <dbReference type="GeneID" id="5004290"/>
    <dbReference type="Gramene" id="ABO98678">
        <property type="protein sequence ID" value="ABO98678"/>
        <property type="gene ID" value="OSTLU_43913"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43913"/>
    <dbReference type="eggNOG" id="KOG2068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051690_0_0_1"/>
    <dbReference type="OMA" id="YIICIPQ"/>
    <dbReference type="OrthoDB" id="498260at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="90"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="214" mass="23469" checksum="D3D3BDCA5BB4B4A5" modified="2007-05-15" version="1" fragment="single">MELASKDDAKGRCPACRTEYDEDAISFDAVPEEELAANAQRAKKREGKAGAANANANGTNGIKAGSGTGANAAQSQSRKHLQNVRVIQRNLVYVVGLSARCCKEEVLRKNDFFGKYGKILKLQVSVNRNGSSSYAGRNADDTGSAYVTFYEENDAMQCIQHIDGTPLDGRILRACFGTTKYCNAFLKYQPCNNPDCLYLHDIGRDNDSFTKEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5E0</accession>
    <name>A4S5E0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_39332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420758.1">
        <property type="nucleotide sequence ID" value="XM_001420721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5E0"/>
    <dbReference type="STRING" id="436017.A4S5E0"/>
    <dbReference type="GeneID" id="5004672"/>
    <dbReference type="Gramene" id="ABO99051">
        <property type="protein sequence ID" value="ABO99051"/>
        <property type="gene ID" value="OSTLU_39332"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39332"/>
    <dbReference type="eggNOG" id="KOG0807">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_1_2_1"/>
    <dbReference type="OMA" id="MRVAVCQ"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110050">
        <property type="term" value="F:deaminated glutathione amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110051">
        <property type="term" value="P:metabolite repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088:SF27">
        <property type="entry name" value="DEAMINATED GLUTATHIONE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088">
        <property type="entry name" value="NITRILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="282" mass="31026" checksum="128EA18BBA78D05A" modified="2007-05-15" version="1">MPRGRHRIACAQMTSTADFQHNLQTVTELCKRAKAEACEALFLPEAFARIGATDASYAEPLDGPIVRACCALAKEYGLWMSLGGYAERDGDGRKRFNSHVMIDPRSGEISGDVYRKIHLFDTDAAVGVDGGGMRESDYTRAGTTLASYDTTFGKVGASICYDLRFPDVYQALRFEHEADVICVPSAFTKSTGQAHWEVLLRARAIETQCYVVAAAQAGKHGETRESYGHAMVIDPWGRIVAKMDDPSNEVGIAVAEIDLALVDSIRTQMPLAEHRRRVRAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5K4</accession>
    <name>A4S5K4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_13119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420624.1">
        <property type="nucleotide sequence ID" value="XM_001420587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5K4"/>
    <dbReference type="STRING" id="436017.A4S5K4"/>
    <dbReference type="GeneID" id="5004654"/>
    <dbReference type="Gramene" id="ABO98917">
        <property type="protein sequence ID" value="ABO98917"/>
        <property type="gene ID" value="OSTLU_13119"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13119"/>
    <dbReference type="eggNOG" id="KOG1543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012184_8_1_1"/>
    <dbReference type="OMA" id="WAFSANA"/>
    <dbReference type="OrthoDB" id="10253408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000332">
        <property type="entry name" value="Cathepsin L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="3">
        <location>
            <begin position="35"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="241" mass="26235" checksum="2C0A13A3271548ED" modified="2007-05-15" version="1">MLGYKPELRDATQTVGATRDADEYKANWKYASVEPLENVDWVERGAVTAPKNQGQCGSCWAFSTTGAIEGINQIRTGRLVSLSEQELVSCSTQNMACNGGLMDNAFKWVQKNGGIDSEFQYPYAAEKLSCNKFKLQLHVATIDGFEDVPPGDEKELEKAVSQQPVSIAIEADTKAFMLYQGGVFDSKECGSQVDHGVLVVVKNSWGNQWGEGGFIRMARRISAETGQCGITTAPSFPTKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5L1</accession>
    <name>A4S5L1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420792.1">
        <property type="nucleotide sequence ID" value="XM_001420755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5L1"/>
    <dbReference type="STRING" id="436017.A4S5L1"/>
    <dbReference type="GeneID" id="5004658"/>
    <dbReference type="Gramene" id="ABO99085">
        <property type="protein sequence ID" value="ABO99085"/>
        <property type="gene ID" value="OSTLU_26804"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26804"/>
    <dbReference type="eggNOG" id="ENOG502QQRP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069725_1_0_1"/>
    <dbReference type="OMA" id="VNRIFIC"/>
    <dbReference type="OrthoDB" id="407127at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35759">
        <property type="entry name" value="BNAA09G03860D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35759:SF1">
        <property type="entry name" value="OS07G0673000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="22388" checksum="5ED5B094DBEFB5BB" modified="2007-05-15" version="1">MVRAPGVWGDGLHWRHRAVPNVENAASRGCELTQERYGRRMRDRKSNAYMVELFETASSSSSTSLNRFDLFHAHAFAWRATNESSVVRLGILFHAKEYPAKDDENFPIDLGKCQCDSTLCLDEKGMSQRNVLWLSLDSCALLAWLDTSSESLRELLTVPELHTTFEGDFGAIQGDVYYFHSLKNRKPSERLFIIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Q2</accession>
    <name>A4S5Q2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26843</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420648.1">
        <property type="nucleotide sequence ID" value="XM_001420611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Q2"/>
    <dbReference type="STRING" id="436017.A4S5Q2"/>
    <dbReference type="GeneID" id="5004911"/>
    <dbReference type="Gramene" id="ABO98941">
        <property type="protein sequence ID" value="ABO98941"/>
        <property type="gene ID" value="OSTLU_26843"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26843"/>
    <dbReference type="eggNOG" id="KOG3080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036007_4_0_1"/>
    <dbReference type="OMA" id="WTHKAKW"/>
    <dbReference type="OrthoDB" id="443772at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="232" mass="27085" checksum="AC9BA55596B8C6B8" modified="2007-05-15" version="1">MDSDDELEREMAALESVKRERAGARDGATARKSYANNEKGLEASLEDFKWTHKAKWIDHMTITGTNAERVVDVNDDLTRETFFYERALESANECVRRLKDLGVPVRRPDDYYAEMVKSDEHMKRVRSELLFEQQQLEIREERRKARESKKYGKQVQAEKIKQRTLDKKSQIKSLDKWRKQRQKSGFADDGKAPFEGAGGDAKRKREDRDSKYGFGGRKKVRAMLSSKRARRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S688</accession>
    <name>A4S688_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421049.1">
        <property type="nucleotide sequence ID" value="XM_001421012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S688"/>
    <dbReference type="GeneID" id="5005109"/>
    <dbReference type="Gramene" id="ABO99342">
        <property type="protein sequence ID" value="ABO99342"/>
        <property type="gene ID" value="OSTLU_17762"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17762"/>
    <dbReference type="HOGENOM" id="CLU_814787_0_0_1"/>
    <dbReference type="OMA" id="MMAPSHY"/>
    <dbReference type="OrthoDB" id="10582275at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="341" mass="35739" checksum="2DB36F16717075C6" modified="2007-05-15" version="1">MTGAEGRARTIDVDGTFAGEGEDMIAALIAASANPATRGGAGRGEGTTRGFEKDGDVVKAKRSFERELVPFDFEDGTSAVDAVVRETNVEVEAKPRERKMTAVPTPKVRGNEEPTKAKTKERRPKPKAVPAPKTVGLIDPRVRANQVCEPQQPALTPEQQAAVLAADGSGKKSKGKVKTATNDERWAQASFQNAPAADQLPMPSFLKDIAPTNSPRVASSSAPPRLDVATPRPQASAAGLKNLLGVKPAAAPQQAKGHALFNNILNSANGDAHPSPPPMMAPSHYAAPPPPQGVQQKLNTLFGVQPQPAQPFPVAPPYPTAPETSGGSFQTLMAKLNAGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6E7</accession>
    <name>A4S6E7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Starch synthase, chloroplastic/amyloplastic</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_41777</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Amyloplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420930.1">
        <property type="nucleotide sequence ID" value="XM_001420893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6E7"/>
    <dbReference type="STRING" id="436017.A4S6E7"/>
    <dbReference type="CAZy" id="GT5">
        <property type="family name" value="Glycosyltransferase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="5005039"/>
    <dbReference type="Gramene" id="ABO99223">
        <property type="protein sequence ID" value="ABO99223"/>
        <property type="gene ID" value="OSTLU_41777"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41777"/>
    <dbReference type="eggNOG" id="ENOG502QTWM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_18_2_1"/>
    <dbReference type="OMA" id="TWCPWYM"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="UniPathway" id="UPA00152"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009501">
        <property type="term" value="C:amyloplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010021">
        <property type="term" value="P:amylopectin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000048">
        <property type="entry name" value="Starch synthase, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825:SF11">
        <property type="entry name" value="ALPHA AMYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825">
        <property type="entry name" value="GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0035">Amyloplast</keyword>
    <keyword evidence="4 11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Starch synthase catalytic" evidence="13">
        <location>
            <begin position="2"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="12">
        <location>
            <begin position="316"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO99223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="525" mass="58039" checksum="747E07765F333A40" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6G2</accession>
    <name>A4S6G2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_7112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C85 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421088.1">
        <property type="nucleotide sequence ID" value="XM_001421051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6G2"/>
    <dbReference type="STRING" id="436017.A4S6G2"/>
    <dbReference type="GeneID" id="5005144"/>
    <dbReference type="Gramene" id="ABO99381">
        <property type="protein sequence ID" value="ABO99381"/>
        <property type="gene ID" value="OSTLU_7112"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7112"/>
    <dbReference type="eggNOG" id="KOG2605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044001_2_2_1"/>
    <dbReference type="OMA" id="CADMARS"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22751">
        <property type="entry name" value="OTU_plant_OTU9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF111">
        <property type="entry name" value="OVARIAN TUMOR DOMAIN-CONTAINING DEUBIQUITINATING ENZYME 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="14"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="140" mass="15742" checksum="ED79402D0F92DCC6" modified="2007-05-15" version="1" fragment="single">DHSRLLLRLDFYGVREKIITGDGNCQFRALSDQLFRDGGENHDAVRAAVCDRLVRNPDDYAPYAAPLDFDEYVQKMSNAGEWGDHITLQAAADAYGVDINIITSYSEHGFIEITPKEGADVNSPRSLWLSFFAEVHYNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6H6</accession>
    <name>A4S6H6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_591</name>
        <name evidence="6" type="ORF">OSTLU_597</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421095.1">
        <property type="nucleotide sequence ID" value="XM_001421058.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422859.1">
        <property type="nucleotide sequence ID" value="XM_001422822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6H6"/>
    <dbReference type="STRING" id="436017.A4S6H6"/>
    <dbReference type="GeneID" id="5004951"/>
    <dbReference type="GeneID" id="5007008"/>
    <dbReference type="Gramene" id="ABO99388">
        <property type="protein sequence ID" value="ABO99388"/>
        <property type="gene ID" value="OSTLU_591"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01218">
        <property type="protein sequence ID" value="ABP01218"/>
        <property type="gene ID" value="OSTLU_597"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_591"/>
    <dbReference type="KEGG" id="olu:OSTLU_597"/>
    <dbReference type="eggNOG" id="KOG1401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010794_0_0_1"/>
    <dbReference type="OMA" id="KGWASRA"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684:SF3">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP01218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="778" mass="83709" checksum="804A8A3811246BD5" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="117" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6V6</accession>
    <name>A4S6V6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27256</name>
        <name evidence="6" type="ORF">OSTLU_29654</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421010.1">
        <property type="nucleotide sequence ID" value="XM_001420973.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422885.1">
        <property type="nucleotide sequence ID" value="XM_001422848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6V6"/>
    <dbReference type="STRING" id="436017.A4S6V6"/>
    <dbReference type="GeneID" id="5005217"/>
    <dbReference type="GeneID" id="5006854"/>
    <dbReference type="Gramene" id="ABO99303">
        <property type="protein sequence ID" value="ABO99303"/>
        <property type="gene ID" value="OSTLU_27256"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01244">
        <property type="protein sequence ID" value="ABP01244"/>
        <property type="gene ID" value="OSTLU_29654"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27256"/>
    <dbReference type="KEGG" id="olu:OSTLU_29654"/>
    <dbReference type="eggNOG" id="KOG0063">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017344_4_1_1"/>
    <dbReference type="OMA" id="IKPQHVD"/>
    <dbReference type="OrthoDB" id="6593433at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060255">
        <property type="term" value="P:regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03236">
        <property type="entry name" value="ABC_RNaseL_inhibitor_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000144">
        <property type="entry name" value="ATP-binding cassette sub-family E member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000152">
        <property type="entry name" value="ATP-binding cassette, sub-family E, member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034348">
        <property type="entry name" value="RLI_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009945">
        <property type="entry name" value="PRK13409.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01868">
        <property type="entry name" value="ABCEFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="79"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="351"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP01244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="611" mass="68840" checksum="9692BB0BE0699FC7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6V8</accession>
    <name>A4S6V8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27258</name>
        <name evidence="4" type="ORF">OSTLU_29652</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421011.1">
        <property type="nucleotide sequence ID" value="XM_001420974.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422884.1">
        <property type="nucleotide sequence ID" value="XM_001422847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6V8"/>
    <dbReference type="STRING" id="436017.A4S6V8"/>
    <dbReference type="GeneID" id="5004932"/>
    <dbReference type="GeneID" id="5006853"/>
    <dbReference type="Gramene" id="ABO99304">
        <property type="protein sequence ID" value="ABO99304"/>
        <property type="gene ID" value="OSTLU_27258"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01243">
        <property type="protein sequence ID" value="ABP01243"/>
        <property type="gene ID" value="OSTLU_29652"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27258"/>
    <dbReference type="KEGG" id="olu:OSTLU_29652"/>
    <dbReference type="eggNOG" id="KOG1716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068551_0_0_1"/>
    <dbReference type="OMA" id="SWTLNWD"/>
    <dbReference type="OrthoDB" id="273181at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019203">
        <property type="term" value="F:carbohydrate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005983">
        <property type="term" value="P:starch catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052832">
        <property type="entry name" value="Starch-Glucan_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46642">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE, SUBGROUP, CATALYTIC DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46642:SF8">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="137"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="279" mass="31323" checksum="E1861C2D26FDD834" modified="2007-05-15" version="1">MRDEASGYEKRAAESAAAGVEEKRPPRGGDAPAPGSWSWTLNWDHVMFDTRGRVIEEPTKEDMARARVLIGSCPRNAEDVDRLVDEAGVEAIVCLQCSLCHAAMEIDWQSVRRRAIERGVMIVQVNVRDFDRLDQAKMLPEAVRKLAAFQAMGKRTYVHCTAGINRASLTVVGYLTFVKMFDLEAALHAVRTSRPQANPYVVSWEIARARLLAHRLEDIYLYSQVDAGGNTIDDGGDWIKRDLERAEKGVIAEVFKRAIDTDLSMYGALIEGDYQQQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6W4</accession>
    <name>A4S6W4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_89032</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421164.1">
        <property type="nucleotide sequence ID" value="XM_001421127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6W4"/>
    <dbReference type="STRING" id="436017.A4S6W4"/>
    <dbReference type="GeneID" id="5004935"/>
    <dbReference type="Gramene" id="ABO99457">
        <property type="protein sequence ID" value="ABO99457"/>
        <property type="gene ID" value="OSTLU_89032"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89032"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_435057_0_0_1"/>
    <dbReference type="OMA" id="NERTFAH"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF5">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="256"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="304"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="382"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="417"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="441"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="452"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="557"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="683" mass="74856" checksum="E652307E8D4084CE" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S746</accession>
    <name>A4S746_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_2522</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Plastid</location>
            <location evidence="9">Chloroplast membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ADP/ATP translocase tlc family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421391.1">
        <property type="nucleotide sequence ID" value="XM_001421354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S746"/>
    <dbReference type="GeneID" id="5005395"/>
    <dbReference type="Gramene" id="ABO99684">
        <property type="protein sequence ID" value="ABO99684"/>
        <property type="gene ID" value="OSTLU_2522"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2522"/>
    <dbReference type="eggNOG" id="ENOG502QSRY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023964_0_1_1"/>
    <dbReference type="OMA" id="PNAVHND"/>
    <dbReference type="OrthoDB" id="2190844at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004667">
        <property type="entry name" value="ADP_ATP_car_bac_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187:SF1">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03219">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="471" mass="51421" checksum="BD8B0F363072F144" modified="2007-05-15" version="1" fragment="single">RLVPMSLMFYFMAFANSIMDAVKDTLVVTAFGGAEQIPYLTVYAVLPTSLLFVSLFARLSSKFGREKLFYMAVTFFMCFFALFTGVLYPMRDVLHPYELAATLATTLPRGLAGGIAVFTNWTYSLFYVAGELWGDVVLSLLFWGLANEITRVSEAGIIYPLLGIGANVAQACSGLFMKFVTTQWHPAGVAPEDMWAAKLKLFMTVVMFCGASIMACHKYICDEARKDPNSAMMEKQRDSKTQSDADKAANKKTKKAGLLSSLMYVFESPEVACLAVMAVAQGLSSIIFQVAWKTQLRIYRPDPTSYAAYMGDVQTYSGMVTGIFMVAAPFLFKNLGWKGTLSVTPKTVIALGWVFFGTSIYALRHGQLAQSSAILPWLVLGGAVIYIVERAAKFSLFKPAEEMVYITLDEDSRTKGKAAVDVLGAQIGKTGGSFMQQGLIFAYGSIIGALPVLVCCHSAIAICWLVAVNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S787</accession>
    <name>A4S787_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS family transporter: sugar</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_43281</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421412.1">
        <property type="nucleotide sequence ID" value="XM_001421375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S787"/>
    <dbReference type="GeneID" id="5005496"/>
    <dbReference type="Gramene" id="ABO99705">
        <property type="protein sequence ID" value="ABO99705"/>
        <property type="gene ID" value="OSTLU_43281"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43281"/>
    <dbReference type="eggNOG" id="KOG1330">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_5_12_1"/>
    <dbReference type="OMA" id="NVNDYGP"/>
    <dbReference type="OrthoDB" id="440755at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF79">
        <property type="entry name" value="PROTEIN SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="45"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="488" mass="52725" checksum="36D131E65A64EC04" modified="2007-05-15" version="1">MPSESSDASRAPREGEAIPAAGTSSSVSFQRRRLARRERWKRYGVVGLITATSLFLYADQNLIGPNMSAIAEEFGMDEKEKDVKLGGLLQLAFFVVGSPASLIIGYYADRVRRVRLFFWTTLIGEGPCMATYWVTSYWQLFALRAMTGIAVGGCLPLLFSLCGDLFASHERSYVASFLTIATGAGVALGQVVAGTVGPAYGWRLPFILTSAPAVVLATVMVLVVDEPKRGAQEEELESGDEAGDVSYKAKMNWSKVKKQLLVKTNILVLAQGLPGTVPWGVFNSYFVDFLHKQKGMTVQNATAAITVFGLGSAFGTIGGGFIGQRMYNKKKSELPILMGLTTAIGALPAYYYLNVNDYGPGRVGLYLSCLVGGVFCSVTPPNVRAILLNVNPPETRGSMFAFYSQIDDVGKGGGPALVALLIVSMGRRVAFNVAFTFWFVCGVILACITFTIDHDVEMERRAVLEALQTDENEVAPIENDGDLNADRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7A2</accession>
    <name>A4S7A2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PsbP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_7791</name>
        <name evidence="2" type="ORF">OSTLU_7889</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421420.1">
        <property type="nucleotide sequence ID" value="XM_001421383.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421451.1">
        <property type="nucleotide sequence ID" value="XM_001421414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7A2"/>
    <dbReference type="STRING" id="436017.A4S7A2"/>
    <dbReference type="GeneID" id="5005503"/>
    <dbReference type="GeneID" id="5005577"/>
    <dbReference type="Gramene" id="ABO99713">
        <property type="protein sequence ID" value="ABO99713"/>
        <property type="gene ID" value="OSTLU_7889"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99744">
        <property type="protein sequence ID" value="ABO99744"/>
        <property type="gene ID" value="OSTLU_7791"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7791"/>
    <dbReference type="KEGG" id="olu:OSTLU_7889"/>
    <dbReference type="eggNOG" id="ENOG502QTGE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071423_0_0_1"/>
    <dbReference type="OMA" id="YSSAEPM"/>
    <dbReference type="OrthoDB" id="1903117at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF7">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="1">
        <location>
            <begin position="56"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="20439" checksum="D14CC29321171A85" modified="2007-05-15" version="1" fragment="single">AYEFTYAVEAESGKPISWAVSRERDTYSSAEPMSPNARQRIVYELLSFKGPLTTVVTVSNTPPALESKAVKEWTAKQVANAVLADKATGRVASGQRVSLAEVDNAIINVIDDVPYYYYEYISQGSPNLREPEATTFRHSYGVTVERDGYLYTLSSSAPEIYWDELARGFDETIKSFRLTTPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7H1</accession>
    <name>A4S7H1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421272.1">
        <property type="nucleotide sequence ID" value="XM_001421235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7H1"/>
    <dbReference type="GeneID" id="5005579"/>
    <dbReference type="Gramene" id="ABO99565">
        <property type="protein sequence ID" value="ABO99565"/>
        <property type="gene ID" value="OSTLU_27483"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27483"/>
    <dbReference type="eggNOG" id="ENOG502SXFB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1819098_0_0_1"/>
    <dbReference type="OrthoDB" id="498741at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="142" mass="15160" checksum="F8D27A2261A7FDED" modified="2007-05-15" version="1">MLSTRARAAPPSFARVSSRSRRARVPAASPRAVEFGARDIASLPRVAASFASAGKLKSPAPQRASRDVKARGVPVLSSLPLVGWAFSSPVVLVVYVFVAIRMYLGYDRTTFGSGVPKIAMCGLWPVLAALSASFRENLKRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S898</accession>
    <name>A4S898_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone deacetylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HDA3502</name>
        <name evidence="3" type="ORF">OSTLU_40681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421586.1">
        <property type="nucleotide sequence ID" value="XM_001421549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S898"/>
    <dbReference type="STRING" id="436017.A4S898"/>
    <dbReference type="GeneID" id="5005865"/>
    <dbReference type="Gramene" id="ABO99879">
        <property type="protein sequence ID" value="ABO99879"/>
        <property type="gene ID" value="OSTLU_40681"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40681"/>
    <dbReference type="eggNOG" id="KOG1344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007727_1_0_1"/>
    <dbReference type="OMA" id="DGFCIFN"/>
    <dbReference type="OrthoDB" id="437693at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09993">
        <property type="entry name" value="HDAC_classIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044150">
        <property type="entry name" value="HDAC_classIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF32">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="2">
        <location>
            <begin position="38"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="323" mass="35041" checksum="C2E902BE731A4E88" modified="2007-05-15" version="1">MVHHSATRHAPGANGAVPVVHHASYSKPVMPRGHRFPMTVFQRVHDILREEGVIARGQTNCFVPGRAPSVDELCRAHDEDYVRDVRASALDAKREREIGLPWSDALVERTLMEVSGTMLTVDLAMKVGLCVNTAGGTHHAHRDRGSGFCIVNDLAVSALRAIDSGAVSRVMIIDLDVHQGDGTAAILANEPGVFTFSAHAKSNFPARKQQSTRDVELPRGMTDDAYMAVVAAAMRESLEDFRPELVIYDAGVDVTSNDTLGHLDLTVEGLYRRERMVMDTVLGAGIPLAGVVGGGYSPDIDELASRHAVLHRVAREMFVDHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8B3</accession>
    <name>A4S8B3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_40543</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421592.1">
        <property type="nucleotide sequence ID" value="XM_001421555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8B3"/>
    <dbReference type="STRING" id="436017.A4S8B3"/>
    <dbReference type="GeneID" id="5005674"/>
    <dbReference type="Gramene" id="ABO99885">
        <property type="protein sequence ID" value="ABO99885"/>
        <property type="gene ID" value="OSTLU_40543"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40543"/>
    <dbReference type="eggNOG" id="KOG3123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066040_1_0_1"/>
    <dbReference type="OMA" id="HNASIMS"/>
    <dbReference type="OrthoDB" id="2516at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000004">
        <property type="entry name" value="Diphthine synthase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036432-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="31113" checksum="1C0EDA3E4331B898" modified="2007-05-15" version="1">MLYLIGLGLGNERDVTLRGLDAIKRCSKVYLEAYTSVLGVDVRAMEALYEKPVRTCDRAFVEQGVDAVLDEALSEDVAFCVVGDAFAATTHSDLVLRAIERGVAVRPVYNASIMNAVAGTGLSLYNFGKAVSICFFTQTWRPDSFYDLIRDNRKSGAHTLCLLDIRVKEPTVRALCKGIEEYEPARFMTAATAAKQMLEVEESRGEGVYGEDTMCVAVARIGQDDEKIRACTLGEMRRVDMGAPLHSLVLVGDVMEIESAMLATHAVKPEDFYDGDAPCQMLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8H1</accession>
    <name>A4S8H1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoplasmin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421766.1">
        <property type="nucleotide sequence ID" value="XM_001421729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8H1"/>
    <dbReference type="STRING" id="436017.A4S8H1"/>
    <dbReference type="GeneID" id="5005703"/>
    <dbReference type="Gramene" id="ABP00060">
        <property type="protein sequence ID" value="ABP00060"/>
        <property type="gene ID" value="OSTLU_27849"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27849"/>
    <dbReference type="HOGENOM" id="CLU_1032045_0_0_1"/>
    <dbReference type="OrthoDB" id="10589262at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="28033" checksum="88A49CF4A7872499" modified="2007-05-15" version="1">MELFQLRVPAGAGRAFTPSRGSMVVLTHVALTCEGPKRASKDERITVQVATRGGGGDGKTDAIALGSVSDAPGREQFAIGGSGLCFGDGERVVVSHNGREAEVCLTGRVEATTASLGGDDSSDESEENSESNGEEDGESDDSESESDGEEDMMVKAKAMAKAAAAARRAEASDEDEDEGEDESESESESESEDSEQDDSDEEESESDDASDDDSSDDSSDDSDALPGSKRKANAKEAKFEDARDARRGGRGGGRGGGRGGGRGKGKFARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8W9</accession>
    <name>A4S8W9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dCMP deaminase</fullName>
            <ecNumber evidence="7">3.5.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">dCMP deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_8218</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.12" evidence="7"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421833.1">
        <property type="nucleotide sequence ID" value="XM_001421796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8W9"/>
    <dbReference type="STRING" id="436017.A4S8W9"/>
    <dbReference type="GeneID" id="5006123"/>
    <dbReference type="Gramene" id="ABP00127">
        <property type="protein sequence ID" value="ABP00127"/>
        <property type="gene ID" value="OSTLU_8218"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8218"/>
    <dbReference type="eggNOG" id="KOG3127">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047993_1_3_1"/>
    <dbReference type="OMA" id="HCEEVGC"/>
    <dbReference type="OrthoDB" id="6710946at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000021">
        <property type="entry name" value="Deoxycytidylate deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086:SF18">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="11">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="125" mass="13797" checksum="3487A9BB7187EF95" modified="2007-05-15" version="1" fragment="single">RPRYLSWDDYFMSVAFLSAQRSKDPNKQVGACIVGKDKLILGVGYNGFPRGCPDNALPWSKKSANDDPLETKYAYVCHAEMNAIMNKNSASVAGGSLFVTMYPCNECAKLVIQAGIKEVVYYEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Y7</accession>
    <name>A4S8Y7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative psaK, PSI-K, subunit X, photosystem I polypeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">psaK</name>
        <name evidence="10" type="ORF">OSTLU_37677</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PsaG/PsaK family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421973.1">
        <property type="nucleotide sequence ID" value="XM_001421936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Y7"/>
    <dbReference type="STRING" id="436017.A4S8Y7"/>
    <dbReference type="GeneID" id="5006013"/>
    <dbReference type="Gramene" id="ABP00267">
        <property type="protein sequence ID" value="ABP00267"/>
        <property type="gene ID" value="OSTLU_37677"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37677"/>
    <dbReference type="HOGENOM" id="CLU_158886_0_0_1"/>
    <dbReference type="OMA" id="VKADWSI"/>
    <dbReference type="OrthoDB" id="1904255at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.40">
        <property type="entry name" value="Chlorophyll a-b binding protein like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000549">
        <property type="entry name" value="PSI_PsaG/PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023618">
        <property type="entry name" value="PSI_PsaG/PsaK_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01241">
        <property type="entry name" value="PSI_PSAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="105" mass="10932" checksum="21A1C53D919C5F8B" modified="2007-05-15" version="1" fragment="single">AAIARRQAAKRDVRVRADWSLGSTENMIVCANTAAIMGAMRFGLMPSVKKNYNGASSHTAMVEQASTKNIGSRDPAGFTAVDVLAAGSFATIISAGEILAGQVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9D9</accession>
    <name>A4S9D9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_89455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422045.1">
        <property type="nucleotide sequence ID" value="XM_001422008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9D9"/>
    <dbReference type="STRING" id="436017.A4S9D9"/>
    <dbReference type="GeneID" id="5005949"/>
    <dbReference type="Gramene" id="ABP00339">
        <property type="protein sequence ID" value="ABP00339"/>
        <property type="gene ID" value="OSTLU_89455"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89455"/>
    <dbReference type="eggNOG" id="KOG3420">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074702_1_0_1"/>
    <dbReference type="OMA" id="IDDEARM"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008988">
        <property type="term" value="F:rRNA (adenine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051720">
        <property type="entry name" value="rRNA_MeTrfase/Polyamine_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23290">
        <property type="entry name" value="RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23290:SF0">
        <property type="entry name" value="RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="29109" checksum="09D4EF7DD301F59B" modified="2007-05-15" version="1">MRARQLESALSANVDETFATPKQRLEQYPTNAALAAGVLHGARARGDVEGKFVVDLGCGTGILSVAATLCDAAVVVGVDVDEDALTRCAENLRAFEPALEVELVCGDVIDGSWTLGGRRMGRGGKRCDTVLMNPPFGAWRGGADVAFLRAAFKIADGAIYSLHKTSTRAHIEKVAKTRFHAREAEVLAQLKYDLPATYGHHREKSVEIAVDLWRFEPTPGAVIDDEALELELAHDASIDGLARDLSSKAHVRGGRGGGRRGGGRRGARGGRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9H4</accession>
    <name>A4S9H4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_37824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422066.1">
        <property type="nucleotide sequence ID" value="XM_001422029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9H4"/>
    <dbReference type="STRING" id="436017.A4S9H4"/>
    <dbReference type="GeneID" id="5006106"/>
    <dbReference type="Gramene" id="ABP00360">
        <property type="protein sequence ID" value="ABP00360"/>
        <property type="gene ID" value="OSTLU_37824"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37824"/>
    <dbReference type="eggNOG" id="KOG0620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016428_1_0_1"/>
    <dbReference type="OMA" id="QVYTYVP"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF68">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4 HOMOLOG 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="304" mass="34037" checksum="4E48B69CAAE9E94F" modified="2007-05-15" version="1">MAQNAAAATSVRVVTYNILAQVYAKSAWFPWTPRALMKSKARRANVQKKLLALDADLMALQELDGYEPSEENDARWKSWLREHGYESRYVQRTKKSNAKKDGSCVAWRASTFALEDSRNLEYNDIGYDLYGRDDANDETNENEARRRYLRDCVGNLTLLRRIKDGALVVFASTHLYWDPECADVKLAQAKMLIAECVKFRDEALIRAEGRPVHVIIGGDFNSDPQSDVYGAMNAAFTSVSNGREPQFTNVTPSFTACIDYVFLSSGVRVVAVDEQPARDTLGEGLPNTGHPSDHLPVAAKIEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9L0</accession>
    <name>A4S9L0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_41993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422188.1">
        <property type="nucleotide sequence ID" value="XM_001422151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9L0"/>
    <dbReference type="STRING" id="436017.A4S9L0"/>
    <dbReference type="GeneID" id="5006145"/>
    <dbReference type="Gramene" id="ABP00505">
        <property type="protein sequence ID" value="ABP00505"/>
        <property type="gene ID" value="OSTLU_41993"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41993"/>
    <dbReference type="eggNOG" id="KOG2590">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077845_1_1_1"/>
    <dbReference type="OMA" id="KYRAFHQ"/>
    <dbReference type="OrthoDB" id="340227at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048255">
        <property type="term" value="P:mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006607">
        <property type="entry name" value="DM15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21071">
        <property type="entry name" value="LARP1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00684">
        <property type="entry name" value="DM15"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="188" mass="22697" checksum="3EB0E7D04E82DFCD" modified="2007-05-15" version="1">MGASPSQKPGRLSHHASPRDIPEFQHPSHTLLDDNGFKQQKYQAFHQRAVDERKRLGCGNSEEMNTLFRFWSYFLRGTFNAKMYKEFCRLAEEDARHNYHYGLQCLFRFYSYGLEKRFRKAVYRDFEEFTMLDYKSGSLYGLEKFWAFHYYYRGDNRPVIREDIKELLDTKFRTLSDFQRAKEQMARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9L9</accession>
    <name>A4S9L9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422194.1">
        <property type="nucleotide sequence ID" value="XM_001422157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9L9"/>
    <dbReference type="GeneID" id="5006251"/>
    <dbReference type="Gramene" id="ABP00511">
        <property type="protein sequence ID" value="ABP00511"/>
        <property type="gene ID" value="OSTLU_28246"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28246"/>
    <dbReference type="HOGENOM" id="CLU_555972_0_0_1"/>
    <dbReference type="OMA" id="IAPRETH"/>
    <dbReference type="OrthoDB" id="10508588at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="491" mass="54588" checksum="9BD008F782686E8F" modified="2007-05-15" version="1">MSGARAETPREDAALLERDVERVVDVERASLGARTSDARARTPRVLALAVGLGALGALGACALARATTPIAPRETHALGVSNAGWLNVRRDAVPDAARLGVDATTTSEATETDEFDVDAWLANPRPVYESTSFTVERSASAWALVVRDARELWKIPVNKRGGGYRLGNVVKRRGKGWLNARSAVVDQPEMYKDTLVYSFLEARTEGVRAFAATVAARERSKRTLSRSALAEVLPRSIVMPMRLSDKVAFMERNEKLIVDAALDFRRSRCPEACNQFVVSLSLVWGGDEDGKFLYDDDEYKESIRVLRSLFAYAKENFPPGFELSIAVTSDADDAMTMYAYAPHLMANPIDSASTIIELAHEVNALITRDGGEQTLLNYYDGQLARRRKDIVAMERYRARLHDFRDAIERARLTAETSERARTAVFAPNWFDILRRRMQWPEDVDMDALDGVDEALFSEVLFGVSEPSVSIGRRPSKVIVLAHDDVLERRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA84</accession>
    <name>A4SA84_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422338.1">
        <property type="nucleotide sequence ID" value="XM_001422301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA84"/>
    <dbReference type="GeneID" id="5006395"/>
    <dbReference type="Gramene" id="ABP00655">
        <property type="protein sequence ID" value="ABP00655"/>
        <property type="gene ID" value="OSTLU_25783"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25783"/>
    <dbReference type="HOGENOM" id="CLU_338424_0_0_1"/>
    <dbReference type="OMA" id="CSEQCAN"/>
    <dbReference type="OrthoDB" id="500008at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="843" mass="90906" checksum="D92F2E9E269DD545" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA99</accession>
    <name>A4SA99_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422347.1">
        <property type="nucleotide sequence ID" value="XM_001422310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA99"/>
    <dbReference type="STRING" id="436017.A4SA99"/>
    <dbReference type="GeneID" id="5006375"/>
    <dbReference type="Gramene" id="ABP00664">
        <property type="protein sequence ID" value="ABP00664"/>
        <property type="gene ID" value="OSTLU_13420"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13420"/>
    <dbReference type="eggNOG" id="KOG1372">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_1"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="2"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="317" mass="35015" checksum="8B86F301D652D864" modified="2007-05-15" version="1">MIGSYVVKQLIQEGKYEVHGLVRYRSDLSNLAGELNNIQLVRGDILDGTRVKQVVAEICPTVIFHFAAQAINGVSYDSAELTLDTNIKGTFNMLEAVRFAGLSNKTRFLLAGSSTEYGKTADTWEGAIPEEAPLAPVSPYGVSKVAADLLAQQYVHSHGMHVVTARFFIQVSAGGTESLAPQEFCRQIAMIELGLQSPVVRHGRITTKRDITDLRDSARVVTKLVDLGEPGESYNIGSGIALSMKDILDTAISLSTRPDITTLFDGARERLYDEKILLSDNRKIRELTGWIPDPNITNTIADILKHWRRKTRTLFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAZ2</accession>
    <name>A4SAZ2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422686.1">
        <property type="nucleotide sequence ID" value="XM_001422649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAZ2"/>
    <dbReference type="GeneID" id="5006584"/>
    <dbReference type="Gramene" id="ABP01003">
        <property type="protein sequence ID" value="ABP01003"/>
        <property type="gene ID" value="OSTLU_29430"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29430"/>
    <dbReference type="HOGENOM" id="CLU_386570_0_0_1"/>
    <dbReference type="OMA" id="DENACHI"/>
    <dbReference type="OrthoDB" id="10480983at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="715" mass="78366" checksum="E911DE32EFCCA829" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB11</accession>
    <name>A4SB11_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA ligase (NAD(+))</fullName>
            <ecNumber evidence="2">6.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_29450</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>NAD(+) + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide.</text>
            <dbReference type="EC" id="6.5.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422695.1">
        <property type="nucleotide sequence ID" value="XM_001422658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB11"/>
    <dbReference type="STRING" id="436017.A4SB11"/>
    <dbReference type="GeneID" id="5006752"/>
    <dbReference type="Gramene" id="ABP01012">
        <property type="protein sequence ID" value="ABP01012"/>
        <property type="gene ID" value="OSTLU_29450"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29450"/>
    <dbReference type="eggNOG" id="ENOG502QWTN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007764_2_1_1"/>
    <dbReference type="OMA" id="HDVEHEI"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17748">
        <property type="entry name" value="BRCT_DNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000012">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.610">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018239">
        <property type="entry name" value="DNA_ligase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005932">
        <property type="entry name" value="PRK07956.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF9">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="OB_DNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01055">
        <property type="entry name" value="DNA_LIGASE_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="13">
        <location>
            <begin position="669"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="638"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="660"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABP01012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="755" mass="79642" checksum="BFF16B1AFC36C171" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB28</accession>
    <name>A4SB28_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS family transporter: hexose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_52000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422705.1">
        <property type="nucleotide sequence ID" value="XM_001422668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB28"/>
    <dbReference type="GeneID" id="5006762"/>
    <dbReference type="Gramene" id="ABP01022">
        <property type="protein sequence ID" value="ABP01022"/>
        <property type="gene ID" value="OSTLU_52000"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_52000"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OMA" id="LIITFTQ"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17315">
        <property type="entry name" value="MFS_GLUT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="18"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="462" mass="48366" checksum="8AFD3BA7FF0C2A7D" modified="2007-05-15" version="1">MTTESRRGADVGPGLAPSAVAASLGAFLFGYHTAACNAPLSALARDLGFADDDYVKGAVVSALVIGGAIGGLTVGGLSDKYGRKWALTATSAPLALGTMLSGMAPNAVTMIAGRFICGLGVGASSQIVPLYLSEIAPPALRGTLNGFRRLAYVFGCLAAFQLAAPLKETGGEGWWRPIFYDAAIPALMLAVGAAFVAQETPVWLLTQSDEKAAEKSRRSLAILQNIRGRAAEQKLSTWSELISDDKNRLPLSLGLSLCALAAFSGSNTVIFYASTVFTSVGINNPEILTWAVGVPNVVGGFVALALSDKMGRRPLLLTSFGGMSACLGILSLAAAGPAQPEAAVALVTIPLYVLFFSLGAGPIPWLLYNEVFPTRIRARAVSACTALNYVSNSIVGATFLPMVGAYGLSGSYGFYTLLCASGYVFVDRFIPETKGLRLEDVESTLKRHARKRSTSRSKSIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB40</accession>
    <name>A4SB40_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ABCG) family transporter: White protein-like protein (ABCG)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_992</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422711.1">
        <property type="nucleotide sequence ID" value="XM_001422674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB40"/>
    <dbReference type="GeneID" id="5006607"/>
    <dbReference type="Gramene" id="ABP01028">
        <property type="protein sequence ID" value="ABP01028"/>
        <property type="gene ID" value="OSTLU_992"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_992"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_57_8_1"/>
    <dbReference type="OMA" id="CAHTHTI"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF41">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP01028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="585" mass="64381" checksum="333FE0B0FB88E5EA" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB45</accession>
    <name>A4SB45_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422713.1">
        <property type="nucleotide sequence ID" value="XM_001422676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB45"/>
    <dbReference type="GeneID" id="5006610"/>
    <dbReference type="Gramene" id="ABP01030">
        <property type="protein sequence ID" value="ABP01030"/>
        <property type="gene ID" value="OSTLU_29482"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29482"/>
    <dbReference type="HOGENOM" id="CLU_138790_0_0_1"/>
    <dbReference type="OrthoDB" id="497675at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="112" mass="11694" checksum="2E5E7690B93BED93" modified="2007-05-15" version="1">MGEALNTRENVAEGTPGRPNLAFVGPASGALCGAFALIQSDNELASPAGLALGAVATLALGYQYAKRFDETPRNPLEWPGPRLMPTLGVLFSLFAFLANVEALPRVLSPLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBA1</accession>
    <name>A4SBA1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422738.1">
        <property type="nucleotide sequence ID" value="XM_001422701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBA1"/>
    <dbReference type="GeneID" id="5006641"/>
    <dbReference type="Gramene" id="ABP01055">
        <property type="protein sequence ID" value="ABP01055"/>
        <property type="gene ID" value="OSTLU_29536"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29536"/>
    <dbReference type="eggNOG" id="ENOG502R35M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2390063_0_0_1"/>
    <dbReference type="OMA" id="AMCAIMW"/>
    <dbReference type="OrthoDB" id="531564at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044980">
        <property type="entry name" value="NDUFB2_plant/fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP01055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="94" mass="10220" checksum="99E287B2E6F47E4B" modified="2007-05-15" version="1">MSAARGALLRLGARLRLAQPMRPASGASRGFASGGGGVTHEGVTLHDASFAHKALGTGFGAVMWFWVFYRFYHDGDTLIYGHAPHFEHDDDDHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQC5</accession>
    <name>A4RQC5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415362.1">
        <property type="nucleotide sequence ID" value="XM_001415325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQC5"/>
    <dbReference type="GeneID" id="4999517"/>
    <dbReference type="Gramene" id="ABO93654">
        <property type="protein sequence ID" value="ABO93654"/>
        <property type="gene ID" value="OSTLU_28615"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28615"/>
    <dbReference type="HOGENOM" id="CLU_2692235_0_0_1"/>
    <dbReference type="OrthoDB" id="10510584at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="74" mass="8036" checksum="5532BFAE7393AD8B" modified="2007-05-15" version="1">MTSASTSSNHSLPALWRHAMKKWGRWQGYAWSTVVVAGAAAYAMSLVVDAGGEKSKVKRDADGGDASRGERRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQI9</accession>
    <name>A4RQI9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_92061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415740.1">
        <property type="nucleotide sequence ID" value="XM_001415703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQI9"/>
    <dbReference type="STRING" id="436017.A4RQI9"/>
    <dbReference type="GeneID" id="4999678"/>
    <dbReference type="Gramene" id="ABO94032">
        <property type="protein sequence ID" value="ABO94032"/>
        <property type="gene ID" value="OSTLU_92061"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92061"/>
    <dbReference type="eggNOG" id="KOG0529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_708610_0_0_1"/>
    <dbReference type="OMA" id="CANGDHA"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008318">
        <property type="term" value="F:protein prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF3">
        <property type="entry name" value="PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="390" mass="43891" checksum="3DA345897BC392BE" modified="2007-05-15" version="1">MAPSARATAMAIELDRLLGARDDASGTRAVRSVEHAPDVSRAALFGTTRGDENASRMPDAFYACGDALVMSHDAVVGVREASARRWEGDDDDADFDAAATALCANGDHATAWNARKRTMKARFDGVEKMSARERDGLVEGARDELAFARAVQSRFPKAPSAWAHRRWVIDAARAAVIGDGSKKDAWALETFREECRACDAAVLKKRLNYAAWSHRAWALRRLLPNRRELLDQELCENERRVRTSVSDHCALHYRSHIVKRALGARPADRRSIVLYEDELSRHLIRQYPGHEALWSYYRFVFDTMICAFPRDGDVFASIKSFIHEQCDVDEIVRVDPARAERDAPTQRRLALAFEIWMNVRVARERGESVVIKHTRATNGSTVEVESKARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQR1</accession>
    <name>A4RQR1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_3023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415778.1">
        <property type="nucleotide sequence ID" value="XM_001415741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQR1"/>
    <dbReference type="GeneID" id="4999751"/>
    <dbReference type="Gramene" id="ABO94070">
        <property type="protein sequence ID" value="ABO94070"/>
        <property type="gene ID" value="OSTLU_3023"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3023"/>
    <dbReference type="eggNOG" id="KOG2338">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052248_1_0_1"/>
    <dbReference type="OMA" id="FRALWFT"/>
    <dbReference type="OrthoDB" id="567116at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF31">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="335" mass="37400" checksum="3449E25358CC230B" modified="2007-05-15" version="1" fragment="single">DASVRVMTFNVLCPEYKRAGTKENDDARESANVEDALRRNEKILDLIFDASPDVLCVQEFWHANEAMRELWTRRLREASYDAAVTPRTSGRCDGLLTAVKRDRLEVKDARDVLFNDCGDRVAHVARVASKANGRETLVVNTHLLFPHNENSSLIRLREVFKILEFLRELQREPAIGGKKLPIVITGDFNGSSSGRVYRFLTSQGFTNALDVCQGREGCATSWVSHLNHHGECVGVDHMFLLNPSKQVLEIGASWKEAVFAMMRAKIVQQGIVDDVAAFKEFDANSDGSLTKDEFIEFANKIGLCGEKSPGLLTAELEALYEACDKDGNGEIDFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQR3</accession>
    <name>A4RQR3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415779.1">
        <property type="nucleotide sequence ID" value="XM_001415742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQR3"/>
    <dbReference type="STRING" id="436017.A4RQR3"/>
    <dbReference type="GeneID" id="4999592"/>
    <dbReference type="Gramene" id="ABO94071">
        <property type="protein sequence ID" value="ABO94071"/>
        <property type="gene ID" value="OSTLU_28753"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28753"/>
    <dbReference type="eggNOG" id="ENOG502SA8E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2125244_0_0_1"/>
    <dbReference type="OMA" id="ILAWTHE"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="114" mass="12740" checksum="51B7E3EA23BE460E" modified="2007-05-15" version="1">MDAEAYERAREGLGAHDAICYCTIGYRSGKYAEKMAKRANDGDAKYFNMYGSILAWTHEGGTLVEPSTGLETKRVHTYGKQWACAADGYEVVYFKNPLAKGLGQMVRGLFRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQY9</accession>
    <name>A4RQY9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase III subunit RPC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415474.1">
        <property type="nucleotide sequence ID" value="XM_001415437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQY9"/>
    <dbReference type="STRING" id="436017.A4RQY9"/>
    <dbReference type="GeneID" id="4999896"/>
    <dbReference type="Gramene" id="ABO93766">
        <property type="protein sequence ID" value="ABO93766"/>
        <property type="gene ID" value="OSTLU_28831"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28831"/>
    <dbReference type="eggNOG" id="KOG2354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_478476_0_0_1"/>
    <dbReference type="OMA" id="NEMDWAK"/>
    <dbReference type="OrthoDB" id="340681at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006886">
        <property type="entry name" value="RNA_pol_III_Rpc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04801">
        <property type="entry name" value="RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="65131" checksum="5BE13D94BEA92AD8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR53</accession>
    <name>A4RR53_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipocalin/cytosolic fatty-acid binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_13756</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415513.1">
        <property type="nucleotide sequence ID" value="XM_001415476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR53"/>
    <dbReference type="STRING" id="436017.A4RR53"/>
    <dbReference type="GeneID" id="4999727"/>
    <dbReference type="Gramene" id="ABO93805">
        <property type="protein sequence ID" value="ABO93805"/>
        <property type="gene ID" value="OSTLU_13756"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13756"/>
    <dbReference type="eggNOG" id="ENOG502S9PN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100756_0_0_1"/>
    <dbReference type="OMA" id="TISIWNT"/>
    <dbReference type="OrthoDB" id="565904at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19438">
        <property type="entry name" value="lipocalin_Blc-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047202">
        <property type="entry name" value="Lipocalin_Blc-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013436019" description="Lipocalin/cytosolic fatty-acid binding domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="59"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="231" mass="25557" checksum="5676161635165A6F" modified="2007-05-15" version="1">MNTKRASRTIVCLVLGIFLDALGGARAQATRARQRAPETACAPIAPVQPFNLTEYVDREWYVVAQKPTSYQPRRDLFCVRANYTLVDAQTISIWNTARRDGVSGRDRNARGLFKLRGIVEDVETPSKLVVGLNFLPSFTYGPYWVVATDTTPESDEFAERGYSWAIISGGPLTTPRGDEGLCEPSGGLWLFVRDPLVSKNVVDQIKATARELGIDTSVLLPVDQEGCTYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRQ5</accession>
    <name>A4RRQ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exonuclease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_13915</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Putative 5'-&gt;3' double-stranded DNA exonuclease which may also contain a cryptic 3'-&gt;5' double-stranded DNA exonuclease activity. May be involved in DNA mismatch repair (MMR).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415611.1">
        <property type="nucleotide sequence ID" value="XM_001415574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRQ5"/>
    <dbReference type="STRING" id="436017.A4RRQ5"/>
    <dbReference type="GeneID" id="4999788"/>
    <dbReference type="Gramene" id="ABO93903">
        <property type="protein sequence ID" value="ABO93903"/>
        <property type="gene ID" value="OSTLU_13915"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13915"/>
    <dbReference type="eggNOG" id="KOG2518">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008978_3_0_1"/>
    <dbReference type="OMA" id="DVQFRAM"/>
    <dbReference type="OrthoDB" id="26491at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09908">
        <property type="entry name" value="H3TH_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09857">
        <property type="entry name" value="PIN_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000011">
        <property type="entry name" value="exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000002">
        <property type="entry name" value="Exonuclease 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037315">
        <property type="entry name" value="EXO1_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044752">
        <property type="entry name" value="PIN-like_EXO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF65">
        <property type="entry name" value="DNA DAMAGE-INDUCIBLE PROTEIN DIN7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0228">DNA excision</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="18">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="17">
        <location>
            <begin position="139"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00060210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO93903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="36790" checksum="13EB219B3169A12D" modified="2007-05-15" version="1">MGIASLLPTLKSISRHAHVGETYAGQVVCVDAYVWLHRGAYACSRELCEGLPTRKHVEYFLNRARTLKRANVRAIYVFDGGRLPGKANEEAQRRRNRSEALAKAKAHARQGNASAANDFYVRAVDITPEMAREVIEALAREGFESLTAPYEADAQMAYLVKNGFVAGVITEDSDLIAHGCRSVFTKMAGDGSGIEIRFEELGRNRGLSFVGFTPDMFLEMCVLSGCDYLPSLNGVGVKKAHSLIRRFKTYNKVLRHMKFEGIAVPKDYESRFVDALLTFKYSWVYCPQRREIVNLNDPVGVLDQSLIDDLPRLIAHSRVGAIDERADPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRW0</accession>
    <name>A4RRW0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_39963</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415971.1">
        <property type="nucleotide sequence ID" value="XM_001415934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRW0"/>
    <dbReference type="STRING" id="436017.A4RRW0"/>
    <dbReference type="MEROPS" id="T01.P02"/>
    <dbReference type="GeneID" id="4999394"/>
    <dbReference type="Gramene" id="ABO94263">
        <property type="protein sequence ID" value="ABO94263"/>
        <property type="gene ID" value="OSTLU_39963"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39963"/>
    <dbReference type="eggNOG" id="KOG0180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_10_0_1"/>
    <dbReference type="OMA" id="CSEQLYG"/>
    <dbReference type="OrthoDB" id="204949at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03759">
        <property type="entry name" value="proteasome_beta_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033811">
        <property type="entry name" value="Proteasome_beta_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF10">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="206" mass="22525" checksum="15D2553305BD9240" modified="2007-05-15" version="1">MSIMSYNGAAVIAMTGKDCVAIASDLRLGINQNQTAAVDYSKLHKIHDRLYLGLTGLIADQLTLAQKLKFKHDMYELRENRVMSPKVFGAVVSATLYEKRFSPYYTEPVVAGLDADGKPYITSMDLIGADASTDDFVVAGDNVESLFGVCESFYKRDLDPEALFEVISHCLTSGVNRDCLSGWGGVVTVVTKGNGTFTRTLKSRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSS0</accession>
    <name>A4RSS0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A, chloroplastic/mitochondrial</fullName>
            <shortName evidence="7">Glu-AdT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GatA</name>
        <name evidence="7" type="synonym">GATA</name>
        <name evidence="10" type="ORF">OSTLU_119596</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This protein may be expected to contain an N-terminal transit peptide but none has been predicted.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416197.1">
        <property type="nucleotide sequence ID" value="XM_001416160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSS0"/>
    <dbReference type="STRING" id="436017.A4RSS0"/>
    <dbReference type="GeneID" id="5000211"/>
    <dbReference type="Gramene" id="ABO94490">
        <property type="protein sequence ID" value="ABO94490"/>
        <property type="gene ID" value="OSTLU_119596"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119596"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_3_1"/>
    <dbReference type="OMA" id="QPASYCG"/>
    <dbReference type="OrthoDB" id="421993at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="9">
        <location>
            <begin position="72"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="554" mass="59481" checksum="B1DDB6D3C8A80741" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSY8</accession>
    <name>A4RSY8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding protein, possibly exosome complex Ribosomal RNA processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Rrp4</name>
        <name evidence="2" type="ORF">OSTLU_119535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416166.1">
        <property type="nucleotide sequence ID" value="XM_001416129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSY8"/>
    <dbReference type="GeneID" id="5000079"/>
    <dbReference type="Gramene" id="ABO94459">
        <property type="protein sequence ID" value="ABO94459"/>
        <property type="gene ID" value="OSTLU_119535"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119535"/>
    <dbReference type="HOGENOM" id="CLU_1404555_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="57"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="21537" checksum="230EEE733803706B" modified="2007-05-15" version="1">MLGTKKPLLLAPGDHFESDSILNTADIPHVTISRTSKLVLGQRQNFKVRTSSSPTPGANVIGIVTKVSQQSIHAMINSSLDAEIPITCLTHSQRNVRVGSAIQATVQSVSSKKVLLTFDVNEKGVANGVLHKGRVFSFRQQVSMGCRCKRWKMQARMKATCPTDIVLSLNQQMWLRTTQRRKTRDVHTLLLECM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSZ6</accession>
    <name>A4RSZ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histidinol-phosphate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">His8</name>
        <name evidence="13" type="ORF">OSTLU_119523</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416159.1">
        <property type="nucleotide sequence ID" value="XM_001416122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSZ6"/>
    <dbReference type="STRING" id="436017.A4RSZ6"/>
    <dbReference type="GeneID" id="5000422"/>
    <dbReference type="Gramene" id="ABO94452">
        <property type="protein sequence ID" value="ABO94452"/>
        <property type="gene ID" value="OSTLU_119523"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119523"/>
    <dbReference type="eggNOG" id="KOG0633">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_1_1"/>
    <dbReference type="OMA" id="NFVQFGR"/>
    <dbReference type="OrthoDB" id="2015537at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885:SF2">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="81"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="409" mass="45568" checksum="6C63CAD07D3E7B4A" modified="2007-05-15" version="1">MISHVGSIRNFKGLSCSRSQHKTHTSRKNHSASRLCSRLQSSSGDISSSNFVRKHILDLQPYTPIVPFEVLSEKLQRPITEIVKLDANENPYGPPPDVYDALRDIKYPHIYPDPESRRLRAALAAECAVPTENLLVGCGADELIDLLLRVVLEPGDKIINTPPTFGMYSFDCNINAGDVIDICRGLSFKIDVEAIEAAVKTHSPKLLFLTSPNNPDGSLIEEDDLLRLLRLPILVVLDEAYIEFASAKSYITQVPSRKNLIVLRTFSKRAALAGLRVGYGAFPSDLIEYIWRVKQPYNVSAIAETAALAALSNPSYLQEVRDKIVFERARMFGLLSEFDFLEPFTSESNFILCRVKRMSAEYVKACLLERGVVIRHYSSPKEIADCIRISVGRPEDTDAVVSALASIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT07</accession>
    <name>A4RT07_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Orfan Protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Osp1</name>
        <name evidence="1" type="ORF">OSTLU_119516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416401.1">
        <property type="nucleotide sequence ID" value="XM_001416364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT07"/>
    <dbReference type="GeneID" id="5000087"/>
    <dbReference type="Gramene" id="ABO94694">
        <property type="protein sequence ID" value="ABO94694"/>
        <property type="gene ID" value="OSTLU_119516"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119516"/>
    <dbReference type="HOGENOM" id="CLU_124641_0_0_1"/>
    <dbReference type="OMA" id="WSLYHNS"/>
    <dbReference type="OrthoDB" id="10456210at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="126" mass="14707" checksum="EEAA4024311ABFFF" modified="2007-05-15" version="1">MLTIRVRPRLEINKWSLYHNSTLSTKTIILDEIVLSLSAQKTVQELSRTSWHQIYDQEAQTELKSDLTTEDRVLCNGTQLMADKRLEEYRIPHAADLVVIRRLFVVEGWKIMTDSNHDSSSDEEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTN9</accession>
    <name>A4RTN9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">BASS family transporter: sodium ion/bile acid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_12281</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416821.1">
        <property type="nucleotide sequence ID" value="XM_001416784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTN9"/>
    <dbReference type="STRING" id="436017.A4RTN9"/>
    <dbReference type="GeneID" id="5001089"/>
    <dbReference type="Gramene" id="ABO95114">
        <property type="protein sequence ID" value="ABO95114"/>
        <property type="gene ID" value="OSTLU_12281"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12281"/>
    <dbReference type="eggNOG" id="KOG2718">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034788_1_0_1"/>
    <dbReference type="OMA" id="IMVAMGC"/>
    <dbReference type="OrthoDB" id="203097at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="SODIUM-BILE ACID COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361:SF30">
        <property type="entry name" value="SODIUM_METABOLITE COTRANSPORTER BASS6, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="266" mass="27850" checksum="3C71F1B0833F9BEE" modified="2007-05-15" version="1">MFSMGITLTLDDFKRVFLKPRVIGLGFFACYVLMPALAFVIGNALGLSGPLLAGLILVGSINGGQASNLCAYIARGDVALSVLMTTATTVGCIFMTPLICKLALGAVVDVDAMGMAISTIQVVLVPVVLGLTLNKYVPKFCRSVEPFSPVVGVTATIILVGGAVANCAAGILGAGMTLQLAAFMLHLIGGLAGYGIMRVFKYSETTCRTVAIETAMKSSAFGFLLASLHFPEYLVRVPSAVSVVWMAVLGSTMAVIWRFIPVPDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTR6</accession>
    <name>A4RTR6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416541.1">
        <property type="nucleotide sequence ID" value="XM_001416504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTR6"/>
    <dbReference type="GeneID" id="5000617"/>
    <dbReference type="Gramene" id="ABO94834">
        <property type="protein sequence ID" value="ABO94834"/>
        <property type="gene ID" value="OSTLU_30358"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30358"/>
    <dbReference type="eggNOG" id="ENOG502S6A7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_970896_0_0_1"/>
    <dbReference type="OMA" id="CAFADER"/>
    <dbReference type="OrthoDB" id="5357at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="302" mass="32569" checksum="8C0AA6D3299F4E72" modified="2007-05-15" version="1">MTRARARGREDETRDPRLISRRDKAANRENAKTWVVVGGLAVAMTAVIALVYENSTDGFLYGVDSIESYADWTGGGDGEFDFASGRGAGGAMDFLSGSAIFGAVVWALGLYYASPVSVVMLFLGRTDSERPSDWLLRKATGTAQMEDASSASKALIACWFLLSGVAVSQLGDAAFGDATWQISSGLGFAVIAGVSELGRPKRVDEATMAKLEAQYADFCAFGEKRLSRSGRCHQSEISKAFRAAYPQHAGEDVLDEMELRSLIANYWPGAERSPRGYYKNLSLLDRDGAPLTDRVSVKDLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTW0</accession>
    <name>A4RTW0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor MYC/MYB N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_92375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416853.1">
        <property type="nucleotide sequence ID" value="XM_001416816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTW0"/>
    <dbReference type="GeneID" id="5000820"/>
    <dbReference type="Gramene" id="ABO95146">
        <property type="protein sequence ID" value="ABO95146"/>
        <property type="gene ID" value="OSTLU_92375"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92375"/>
    <dbReference type="HOGENOM" id="CLU_820364_0_0_1"/>
    <dbReference type="OrthoDB" id="1926382at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025610">
        <property type="entry name" value="MYC/MYB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14215">
        <property type="entry name" value="bHLH-MYC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor MYC/MYB N-terminal" evidence="4">
        <location>
            <begin position="253"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="28"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="339" mass="37677" checksum="D839EB7494790555" modified="2007-05-15" version="1" fragment="single">VIVIGGLDIARAIASVQAVIEREMASRDELTRRTSATLDIGPRARERDAQEHPLVSHPGAMLQSLSVRSSDDTRVRGNEARGGQKSALAAKTDASSERRHVSPDSALETTGTFGSFESEDGSLEDDDNRMDAANNKRVESMTDFMNSARESQTSAQTMASADLTRSGSRQQIDRLLDEAMSMFHRDGPLVNPLERCASTSSMEMRMRFVCEAKGFDYGLFWEFDEDKKSLTCVSRVCIPDASGISLFVDTSFTMFKRFSMGFGMPGRIGYTGNYEWHEDIRQLPAWSFQRKRQAEQANIRTVIGVPLDDGIVEFGTRSVADHNVTSVQYIQKLCQVSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="130" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTZ1</accession>
    <name>A4RTZ1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">SDG3501</name>
        <name evidence="19" type="ORF">OSTLU_14486</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416870.1">
        <property type="nucleotide sequence ID" value="XM_001416833.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RTZ1"/>
    <dbReference type="GeneID" id="5000753"/>
    <dbReference type="Gramene" id="ABO95163">
        <property type="protein sequence ID" value="ABO95163"/>
        <property type="gene ID" value="OSTLU_14486"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14486"/>
    <dbReference type="eggNOG" id="KOG1080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_233807_0_0_1"/>
    <dbReference type="OMA" id="CHRHCRV"/>
    <dbReference type="OrthoDB" id="496514at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15662">
        <property type="entry name" value="ePHD_ATX1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15495">
        <property type="entry name" value="PHD_ATX3_4_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10518">
        <property type="entry name" value="SET_SETD1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.390.10">
        <property type="entry name" value="SAND domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041956">
        <property type="entry name" value="ATX1/2_ePHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042011">
        <property type="entry name" value="ATX3/4/5_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010919">
        <property type="entry name" value="SAND-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000770">
        <property type="entry name" value="SAND_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011124">
        <property type="entry name" value="Znf_CW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01342">
        <property type="entry name" value="SAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07496">
        <property type="entry name" value="zf-CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63763">
        <property type="entry name" value="SAND domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50864">
        <property type="entry name" value="SAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51050">
        <property type="entry name" value="ZF_CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="242"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="13">
        <location>
            <begin position="394"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="SAND" evidence="15">
        <location>
            <begin position="544"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="622"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="18">
        <location>
            <begin position="681"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="CW-type" evidence="17">
        <location>
            <begin position="1337"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="14">
        <location>
            <begin position="1644"/>
            <end position="1760"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="16">
        <location>
            <begin position="1766"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="10">
        <location>
            <begin position="394"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="371"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="482"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="832"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="882"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="835"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="856"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="917"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="938"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="962"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50864"/>
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    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO95163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1782" mass="198866" checksum="234A9557BBA949F0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU63</accession>
    <name>A4RU63_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate dehydrogenase assembly factor 3</fullName>
            <shortName evidence="6">SDH assembly factor 3</shortName>
            <shortName evidence="6">SDHAF3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_92416</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the complex I LYR family. SDHAF3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416903.1">
        <property type="nucleotide sequence ID" value="XM_001416866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU63"/>
    <dbReference type="STRING" id="436017.A4RU63"/>
    <dbReference type="GeneID" id="5000683"/>
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        <property type="protein sequence ID" value="ABO95196"/>
        <property type="gene ID" value="OSTLU_92416"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92416"/>
    <dbReference type="eggNOG" id="KOG4100">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102310_2_0_1"/>
    <dbReference type="OMA" id="IEFASEW"/>
    <dbReference type="OrthoDB" id="278329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006105">
        <property type="term" value="P:succinate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20270">
        <property type="entry name" value="Complex1_LYR_SDHAF3_LYRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008381">
        <property type="entry name" value="SDHAF3/Sdh7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13137">
        <property type="entry name" value="DC11 ACN9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13137:SF6">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="114" mass="13327" checksum="60F2A9C6AC088664" modified="2007-05-15" version="1">MSGVGRIFSLYRSILRAHRNLPGPMKELGGTYAREEFRTHLRSEKIQEKQWRTFVESWQSYVESLRGDAGKVVSGDLTEDVIEQLTPEQRQQLERLKDEAMRLKLELDASEFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU64</accession>
    <name>A4RU64_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_30510</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom22 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4RU64"/>
    <dbReference type="GeneID" id="5001007"/>
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        <property type="protein sequence ID" value="ABO95197"/>
        <property type="gene ID" value="OSTLU_30510"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30510"/>
    <dbReference type="eggNOG" id="KOG4111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Tom22_pln"/>
    </dbReference>
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        <source>
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        </source>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="84" mass="9310" checksum="ECBA11E16742E68B" modified="2007-05-15" version="1">MEITPDYGAEEAKSAKPVRLGWADASRLTRKLAVHTGKAAWTFGTSFLVLIVPLIVQLHREEQLIELEKEQLGVLNQPTGLQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU85</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14563</name>
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    <organism evidence="2 3">
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="292" mass="32314" checksum="CB666586FF27FD9C" modified="2007-05-15" version="1">MRGENAEEDYIDVYASSRARRVARHAKAASTTLESQRRERHLLLEAVTQQKELLDVEQKRADDAEDELEKVTAQADALSKKLDDLMSTFMSRKLLERTCETPTPSSSVAATSTLQLENERLKREMYDMEKRHAAEIADLRADLRADKPNALTAEERRRLLTEIAEARKEIAVAKEARAKALSEAIDLRTKLESLGAAASVNGVSGANNAFTPAASVNGVSGANNASTPPKTPEWANIDWDAAHAEMDSIKAEKQRITPKLDSGKLPSLEEEIDWEAAYSDIDATRARRKILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU90</accession>
    <name>A4RU90_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU90"/>
    <dbReference type="STRING" id="436017.A4RU90"/>
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        <property type="protein sequence ID" value="ABO95210"/>
        <property type="gene ID" value="OSTLU_14566"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14566"/>
    <dbReference type="HOGENOM" id="CLU_287063_0_0_1"/>
    <dbReference type="OMA" id="HEAFPLE"/>
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    </dbReference>
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        <location>
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            <end position="53"/>
        </location>
    </feature>
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        <location>
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        <location>
            <begin position="1086"/>
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        </location>
    </feature>
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        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="462"/>
        </location>
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        <location>
            <begin position="1106"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1220" mass="136631" checksum="7E09C433247A49AC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUA5</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92429</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001416887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUA5"/>
    <dbReference type="GeneID" id="5000966"/>
    <dbReference type="Gramene" id="ABO95217">
        <property type="protein sequence ID" value="ABO95217"/>
        <property type="gene ID" value="OSTLU_92429"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92429"/>
    <dbReference type="eggNOG" id="ENOG502SCBY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_793078_0_0_1"/>
    <dbReference type="OMA" id="GYLEYYY"/>
    <dbReference type="OrthoDB" id="534847at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="35014" checksum="A245637194319240" modified="2007-05-15" version="1">MITANRASSSSSSKTNDGGEEGAFIASAIAMGVPTLATLAYPSALVTNGLGLECATPLFGQSFSSLASVQHFSNAFGTDAFALIALTALYTLADAAKNSRLNSETYQRLALAMVLFTGSFAVAFLGAYLQSQATGETGPNAAAVGGLLVTFAPAFATSVKAIREYGPGHDETWARVGKDFAEAKNLNERSETGGYLELFYKVSFWTSLVVGGSFAFSPLSPLAIVNEMEPSSQLIQRAFGLATVFLLAPTQYILIDAAKRGRLGGGTFKKLNLSIAASIALIDWMTIYTFGAATALSPTAAQLENASGGVYNYVGALAVSASIVAVYLYQGVFAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUG4</accession>
    <name>A4RUG4_OSTLU</name>
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        <recommendedName>
            <fullName evidence="3">WRC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_14618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO94960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUG4"/>
    <dbReference type="GeneID" id="5000937"/>
    <dbReference type="Gramene" id="ABO94960">
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        <property type="gene ID" value="OSTLU_14618"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14618"/>
    <dbReference type="HOGENOM" id="CLU_418214_0_0_1"/>
    <dbReference type="OrthoDB" id="10478637at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF08879">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51667">
        <property type="entry name" value="WRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRC" evidence="3">
        <location>
            <begin position="374"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="545"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="627"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="656" mass="72411" checksum="63FE61F530373567" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUJ1</accession>
    <name>A4RUJ1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">T-complex protein 1 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_34049</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416968.1">
        <property type="nucleotide sequence ID" value="XM_001416931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUJ1"/>
    <dbReference type="STRING" id="436017.A4RUJ1"/>
    <dbReference type="GeneID" id="5000580"/>
    <dbReference type="Gramene" id="ABO95261">
        <property type="protein sequence ID" value="ABO95261"/>
        <property type="gene ID" value="OSTLU_34049"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34049"/>
    <dbReference type="eggNOG" id="KOG0360">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_5_1_1"/>
    <dbReference type="OMA" id="RGPNDYQ"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03335">
        <property type="entry name" value="TCP1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000009">
        <property type="entry name" value="T-complex protein 1 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000070">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012715">
        <property type="entry name" value="Chap_CCT_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02340">
        <property type="entry name" value="chap_CCT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="542" mass="58634" checksum="0C70DE8999BD4F90" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUN7</accession>
    <name>A4RUN7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
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    <dbReference type="EMBL" id="CP000583">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="Gramene" id="ABO95284">
        <property type="protein sequence ID" value="ABO95284"/>
        <property type="gene ID" value="OSTLU_30685"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_271854_0_0_1"/>
    <dbReference type="OMA" id="HALWAYT"/>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ARM-like"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <end position="259"/>
        </location>
    </feature>
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            <end position="567"/>
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        <location>
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            <end position="846"/>
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            <end position="1082"/>
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            <end position="127"/>
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            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
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            <end position="555"/>
        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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        <location>
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            <end position="896"/>
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    </feature>
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            <end position="1103"/>
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        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="ABO95284.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1362" mass="151310" checksum="2E80075A2CC3E2E7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUY5</accession>
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        <submittedName>
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        </submittedName>
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        <name evidence="8" type="ORF">OSTLU_30787</name>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO95336.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="594" mass="63625" checksum="599857CEFDBE0234" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV50</accession>
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        <recommendedName>
            <fullName evidence="5">Cytochrome c oxidase assembly factor 5</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">OSTLU_30848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the PET191 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ABO95073"/>
        <property type="gene ID" value="OSTLU_30848"/>
    </dbReference>
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        <property type="component" value="Chromosome 3"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
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    </dbReference>
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        <property type="entry name" value="Pet191_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8056" checksum="17B300A762274E24" modified="2007-05-15" version="1">MSKSCSGMLAEFLDCVESSACVKKHGHTLKQCASPTWTEHAPSECEVKRSNYFACRKGQLDMRARLRGNKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVA7</accession>
    <name>A4RVA7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_14839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417106.1">
        <property type="nucleotide sequence ID" value="XM_001417069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVA7"/>
    <dbReference type="STRING" id="436017.A4RVA7"/>
    <dbReference type="GeneID" id="5000959"/>
    <dbReference type="Gramene" id="ABO95399">
        <property type="protein sequence ID" value="ABO95399"/>
        <property type="gene ID" value="OSTLU_14839"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14839"/>
    <dbReference type="eggNOG" id="ENOG502SVWY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_646235_0_0_1"/>
    <dbReference type="OMA" id="DARRCMV"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="46007" checksum="D804119CFA0C7A50" modified="2007-05-15" version="1">MTRALSSTAFDATYARSDDAFGANAAISAYEGEVQRLVSDDVPMALMLVFAKRYPERSALGAYALSLPKEAADTPALYEDESLEALVPMLSLHFVDQVDAARREFAMSCADARQIVAKMSDEPALEDLEFAWAWSMVRSRAITFAVKKSGTDVIERKRCLVPVCDVLNHSPTSTSDDSDDGPNVSIESNDVGESIWKTTRDVAKGQALRWTYGELSNEEMWLWYGFVPSTPSHGDCSVVFNLPDTVFANGLNAVAKEDREETAALRRRLLERCGALGLNEGEELSFVLTMRGNPKVLGGIAGLMCCDADEVVAVAASAVIASNGGGDGSLFSFKPETRRRAGRYVAWLLTQVEAFVCGATDAEIAELERTAEAVGGEFAARFRTAKRLRTGAKSTFAAVQGVLTEESLLKNGSWIDDATKTLIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVH5</accession>
    <name>A4RVH5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417138.1">
        <property type="nucleotide sequence ID" value="XM_001417101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVH5"/>
    <dbReference type="GeneID" id="5001368"/>
    <dbReference type="Gramene" id="ABO95431">
        <property type="protein sequence ID" value="ABO95431"/>
        <property type="gene ID" value="OSTLU_30977"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30977"/>
    <dbReference type="eggNOG" id="ENOG502QWFT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065697_1_1_1"/>
    <dbReference type="OMA" id="FNLMGIW"/>
    <dbReference type="OrthoDB" id="47210at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36009">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36009:SF3">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="252" mass="26799" checksum="45C200AA7B980317" modified="2007-05-15" version="1">MTARGARRCATTRRASTPEAREASDGSFEWYREPQRVATACAWVALGSFATFGAPSGTSAFDLELVKSLVSAPFTGAVNPLFEALFNSLGVVPATYACLMMPGAKGNKSPFPAALCVGASFALGFFALGPYLVTREPRTRVKRSELGFVTRNIWESKLNAAALLGFAAYLAFYGASNVTPDTLAGFATLFKEQSMLACVSTCDLIVLSLCVAPAIAEDMRRRDVDDANALAFASVPVLGPACWLLVRPSLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVS9</accession>
    <name>A4RVS9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417202.1">
        <property type="nucleotide sequence ID" value="XM_001417165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVS9"/>
    <dbReference type="GeneID" id="5001629"/>
    <dbReference type="Gramene" id="ABO95495">
        <property type="protein sequence ID" value="ABO95495"/>
        <property type="gene ID" value="OSTLU_92586"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92586"/>
    <dbReference type="HOGENOM" id="CLU_712483_0_0_1"/>
    <dbReference type="OMA" id="HRERWES"/>
    <dbReference type="OrthoDB" id="498970at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="328"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="388" mass="42585" checksum="1DE61E515CE7296F" modified="2007-05-15" version="1">MPRESLRHAIPSSYDEEMEQLRVALEISARASTSHDVHASSSARNSLRQSAAPHVTTSPRFVNGSGASTRTAGRTGRVLVDDARARRPARARDDFADDDDDARATLAERLERRHGVSARDAQRVVDVLDGDYARAEDVCLIVKMVPTSVDRAIAHLRNVGWDVDLALSRMLDASKTSPNAETEREELKRRARSMRRPGGDGKADEARTVKQNLNYTPGAGHRESESGFSSASFRASPASRARDEETERYHRERWESEISDRAAQANKAKSKWDSSQPTAASTPRTASGSEHARETLRSEPPKPSHSAPRPSRASDPPLATLEREGLVQVLTALGVEPSSSSITAVRSAYRKAALRFHPDRLSAAGALERSYKSDVWKLLSSKMDAYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVV2</accession>
    <name>A4RVV2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-alpha-acetyltransferase 40</fullName>
            <ecNumber evidence="4">2.3.1.257</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_31107</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-seryl-[histone H2A] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12742"/>
            <dbReference type="Rhea" id="RHEA-COMP:12744"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50596"/>
            <dbReference type="Rhea" id="RHEA-COMP:12740"/>
            <dbReference type="Rhea" id="RHEA-COMP:12743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. NAA40 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.257" evidence="4"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417476.1">
        <property type="nucleotide sequence ID" value="XM_001417439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVV2"/>
    <dbReference type="STRING" id="436017.A4RVV2"/>
    <dbReference type="GeneID" id="5001597"/>
    <dbReference type="Gramene" id="ABO95769">
        <property type="protein sequence ID" value="ABO95769"/>
        <property type="gene ID" value="OSTLU_31107"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31107"/>
    <dbReference type="eggNOG" id="KOG2488">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051699_1_2_1"/>
    <dbReference type="OMA" id="HRNARFI"/>
    <dbReference type="OrthoDB" id="495500at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043998">
        <property type="term" value="F:histone H2A acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010485">
        <property type="term" value="F:histone H4 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039949">
        <property type="entry name" value="NAA40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="157" mass="18037" checksum="73F804341677EE3C" modified="2007-05-15" version="1">MSTSDRDWCFEVTEANMRAAYERTWGWDATEKRRELNNGAARFVLVRSRESGRPVAFVHFRFEREDEDVDNPVGYVYELQCEAAHQRRALGETLVRTVETVSKKLGMEAVVLTVLKTNVGAYEFYTKKMGYVVDELSPDESVDEGSSHYLILSKRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVZ4</accession>
    <name>A4RVZ4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417234.1">
        <property type="nucleotide sequence ID" value="XM_001417197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVZ4"/>
    <dbReference type="GeneID" id="5001396"/>
    <dbReference type="Gramene" id="ABO95527">
        <property type="protein sequence ID" value="ABO95527"/>
        <property type="gene ID" value="OSTLU_24408"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24408"/>
    <dbReference type="eggNOG" id="ENOG502SCZE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1079241_0_0_1"/>
    <dbReference type="OMA" id="AYCTTRN"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="26262" checksum="1027C390EF8801B0" modified="2007-05-15" version="1">MPASARALERARAAVELDVARDFPAAARAYRDAAAALDADADADADGADGLRRKAREYRARADELEATTRETTVDYTSLVGVASGAARAKTTMETKTRDAGGARVVGGAAAVGACAGFALLGPVSAVVGAGAMAYGTTRRDGVGSACSGAGKMAANAYSSVKRWNREHAVTTKAAAACATGAKAVKKLDDEYKIREKTAKAVTGTARAASEFNEKHGVTKKIGEGVSVGLDVVTKKLGGVDARDEASSEGARLPSAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWC2</accession>
    <name>A4RWC2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycine transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_31288</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417555.1">
        <property type="nucleotide sequence ID" value="XM_001417518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWC2"/>
    <dbReference type="GeneID" id="5001353"/>
    <dbReference type="Gramene" id="ABO95848">
        <property type="protein sequence ID" value="ABO95848"/>
        <property type="gene ID" value="OSTLU_31288"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31288"/>
    <dbReference type="eggNOG" id="ENOG502S0MY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064906_1_1_1"/>
    <dbReference type="OMA" id="DRRPFYW"/>
    <dbReference type="OrthoDB" id="67004at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30506">
        <property type="entry name" value="INNER MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30506:SF3">
        <property type="entry name" value="UPF0126 INNER MEMBRANE PROTEIN YADS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycine transporter" evidence="6">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine transporter" evidence="6">
        <location>
            <begin position="109"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="24764" checksum="DE6B7002AF249FFB" modified="2007-05-15" version="1">MPRYPNFTVPGALRLADYFGTSSFAMTGSLLAAASGMDAFGCTAVGTITAVGGGTVRDILLGQGRRAFWMEEQEYLWIAAGTALATFCGWESAKKQFGFTDDDYWIEASDALGVGAFCVIGTQNGIRAGVPMIAQVLCGIMTATFGGIVRDILVQRPTRIFHSYADIYATTAATGALAYIIARQAGAPPSLRIIAGVSAGIGLRVAADTYDIRLPVYNAENAKKSAASKGDKRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWK2</accession>
    <name>A4RWK2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO95885"/>
        <property type="gene ID" value="OSTLU_31365"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="37804" checksum="1C06E3C047E92C3C" modified="2007-05-15" version="1">MGARQGGRRRAAKPGVAKQAKSGPPRGATTSRVVAIEGAIEGAYAAIEDGRVDEGLATLRAEAKKHPNDASLAETLAMTLAEFGTQEEAIAALKRAAMLSPTEGYEKFMYLGQLLDDGEAATKCTRQGLAILEAQAHKGDEDAQGAHASACCALAEQILGTADEMDAETSAQVEELINRAKASDPVSAEPLQLLASLRNEQGKTDEALKILKESIQMWRQGAMHRDEDEENGAEEFQHEFNVSFEFRFETAKLLLELDTTTEIAIDILCELLRERDDNVDVWYMLAYAHHGALEFDVALEHLEQGEEIVRQRGGDEAALEMFEELRAAITESKATIESGKGPADMDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWQ9</accession>
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    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417623.1">
        <property type="nucleotide sequence ID" value="XM_001417586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWQ9"/>
    <dbReference type="GeneID" id="5001655"/>
    <dbReference type="Gramene" id="ABO95916">
        <property type="protein sequence ID" value="ABO95916"/>
        <property type="gene ID" value="OSTLU_31423"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31423"/>
    <dbReference type="HOGENOM" id="CLU_194843_0_0_1"/>
    <dbReference type="OMA" id="WEWFNNA"/>
    <dbReference type="OrthoDB" id="497223at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="82" mass="8566" checksum="68B2F52786C00E44" modified="2007-05-15" version="1">MFAVSSTRVVVNAANTSGTKRVAGKKAAAGKPGQKKGFFDWLLEKSVRDSGVIGAGYEDDLKSGQYKPKGGLNISEGGSFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWW9</accession>
    <name>A4RWW9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417897.1">
        <property type="nucleotide sequence ID" value="XM_001417860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWW9"/>
    <dbReference type="GeneID" id="5002159"/>
    <dbReference type="Gramene" id="ABO96190">
        <property type="protein sequence ID" value="ABO96190"/>
        <property type="gene ID" value="OSTLU_31485"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31485"/>
    <dbReference type="HOGENOM" id="CLU_765901_0_0_1"/>
    <dbReference type="OMA" id="IHEPLIG"/>
    <dbReference type="OrthoDB" id="10396400at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="362" mass="39731" checksum="FF726AA1BB4CDE28" modified="2007-05-15" version="1">MSKRAQFTVDDDDEGGFVDDDGGLEDDDKARLLASLGPDAPPAHAVGAYEQQKDVEIGPGVDADESDLVDDIFDSSEEAKQNANSTNVFCRCNLASSILLIASMALLVYTMVNPATRDAVTKFALSSPTERHQFNNVKKDPKTGRPTVELMDGEDEADEEAGRLGDWWRLESLKGSESPSKTHNQWDLSGLMLYSDDDCKDELAAQSFELASESATHAWQKRAEKGWGYLADQQGAFIHEPLIGGSRISVHLQSAPRCLKISTCFDAPGRRRALLQSSDEAEALASAQAEANVCDDTHFPSTLALFRYGKQTEEWDRLLQYEGTGVSDGVLNYGGAKHKVRTFNFKNADFTTEGAKIYSENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXC6</accession>
    <name>A4RXC6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sfi1 spindle body domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417726.1">
        <property type="nucleotide sequence ID" value="XM_001417689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXC6"/>
    <dbReference type="GeneID" id="5002133"/>
    <dbReference type="Gramene" id="ABO96019">
        <property type="protein sequence ID" value="ABO96019"/>
        <property type="gene ID" value="OSTLU_15380"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15380"/>
    <dbReference type="HOGENOM" id="CLU_336898_0_0_1"/>
    <dbReference type="OMA" id="MWISATH"/>
    <dbReference type="OrthoDB" id="10532388at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="810" mass="88918" checksum="F45DFAA3C9E3F7DA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXF3</accession>
    <name>A4RXF3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Patatin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_24547</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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        </source>
    </evidence>
    <sequence length="469" mass="52949" checksum="4609DD7C5F024C7D" modified="2007-05-15" version="1">MADAKDILGIPRGGASAPKSRAKAKPSLKPPKGVHREVWQITRGREGDDERDDARAAIVPSALSLHGMKDKRKITARTVTWQWQPFRNSARTDQLQLKHWVKKAVGGAQPTLMGTNGGDVGGDYAFAKYNKKIEMLKYTSDEYERVLKHLDDSWTKEETDYLFEQLERFDLRFIVVVDRWDFASQQTRTVEDLKVRYYSIAKTLIETRAESPEEAAAHQIVKMPFNAQHELDRKVALNTLLNRTNGEMKEEAEILKRVREIEKRRRTENQALLQKATAVFSTSRTHMVQNPVSIDDVRADFETLAPELPLRGSAALKPGPYLRGQHFITVANEQANAAQGGARFAKRIDQSLEDLGVKTPSMNTHAVCAGWLKLREETIELLRVRKKLVTVYERLVAKGKTPGYIPGMADVEAKKAVGGLEHKIVPRRVASAGEIKREDSIPPKPASMKRKAVETPTRGIQKVQRHKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXX0</accession>
    <name>A4RXX0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SDG3511</name>
        <name evidence="6" type="ORF">OSTLU_31845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418034.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABO96364"/>
        <property type="gene ID" value="OSTLU_31845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31845"/>
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        <property type="component" value="Chromosome 5"/>
    </dbReference>
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        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SET AND MYND DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SET"/>
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    </dbReference>
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        <property type="entry name" value="SET"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="101"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="654" mass="71753" checksum="3C7C2661AEF9ECA5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXX6</accession>
    <name>A4RXX6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIF subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_94390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TFIIF alpha subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417829.1">
        <property type="nucleotide sequence ID" value="XM_001417792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXX6"/>
    <dbReference type="STRING" id="436017.A4RXX6"/>
    <dbReference type="GeneID" id="5001957"/>
    <dbReference type="Gramene" id="ABO96122">
        <property type="protein sequence ID" value="ABO96122"/>
        <property type="gene ID" value="OSTLU_94390"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94390"/>
    <dbReference type="eggNOG" id="KOG2393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_526182_0_0_1"/>
    <dbReference type="OMA" id="MTLCFSC"/>
    <dbReference type="OrthoDB" id="498976at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001096">
        <property type="term" value="F:TFIIF-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008851">
        <property type="entry name" value="TFIIF-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011">
        <property type="entry name" value="TFIIF-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05793">
        <property type="entry name" value="TFIIF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="229"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="404"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="410"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="518" mass="56550" checksum="51A9D43B4714ED9E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXY5</accession>
    <name>A4RXY5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417835.1">
        <property type="nucleotide sequence ID" value="XM_001417798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXY5"/>
    <dbReference type="GeneID" id="5001787"/>
    <dbReference type="Gramene" id="ABO96128">
        <property type="protein sequence ID" value="ABO96128"/>
        <property type="gene ID" value="OSTLU_31860"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31860"/>
    <dbReference type="eggNOG" id="KOG2131">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1878892_0_0_1"/>
    <dbReference type="OrthoDB" id="438164at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF21">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="136" mass="14960" checksum="D77027A2DDDC4762" modified="2007-05-15" version="1">MSNGFETLFGAYDDLEYVGDANVAYSFGVGGQFSGVPMHTHGPGWSESLIGRKHWFLAPPDATPNFDPNVTAYAWALEALRRGDVRDGEGGILECTVNAGESIYFPPNWWHATVNLDESVFISSFVNSVQRARDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXZ7</accession>
    <name>A4RXZ7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418082.1">
        <property type="nucleotide sequence ID" value="XM_001418045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXZ7"/>
    <dbReference type="STRING" id="436017.A4RXZ7"/>
    <dbReference type="GeneID" id="5001997"/>
    <dbReference type="Gramene" id="ABO96375">
        <property type="protein sequence ID" value="ABO96375"/>
        <property type="gene ID" value="OSTLU_31872"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31872"/>
    <dbReference type="eggNOG" id="KOG3033">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_724415_0_0_1"/>
    <dbReference type="OrthoDB" id="498910at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774:SF17">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="42152" checksum="37BB97C77AB687D7" modified="2007-05-15" version="1">MTTRHAYAIANAFPSATKGDDSGNPAAVVLLPDDGPWPPDAVMQAAASELGLSETAFAKRADVEVVGAMVHRMYDIRWFTPKCEINLCGHASMATAHEIFRAPGNEHVTKIGFLYGKPRDVCDGTQVKAAYESLFVWKDLDGGVESSYAMALPEERARSFPDALGEDGFLHPQEIVNMIRGCFGDDHERSNSQSSATSKAKYELRYNFIGDLFFIIDTDDAPDEVFEACFDRFMNHAPDLKAISEVGRCFIEEMKYDFEMVQGFRGLCVLLTVKNRPNHSYDFYTRWFGPDVGIDEDPVTGSAASGYARFLDDKLPEVVGKKRGCQMSKPRGDITVSLSDNPYPDTDVHVEVVGKVATRSSGVLEVSVLKDGDISVVNRRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="121" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY66</accession>
    <name>A4RY66_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TufM</name>
        <name evidence="10" type="ORF">OSTLU_12576</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418116.1">
        <property type="nucleotide sequence ID" value="XM_001418079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY66"/>
    <dbReference type="STRING" id="436017.A4RY66"/>
    <dbReference type="GeneID" id="5001942"/>
    <dbReference type="Gramene" id="ABO96409">
        <property type="protein sequence ID" value="ABO96409"/>
        <property type="gene ID" value="OSTLU_12576"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12576"/>
    <dbReference type="eggNOG" id="KOG0460">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_0_0_1"/>
    <dbReference type="OMA" id="EGDKEWG"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046686">
        <property type="term" value="P:response to cadmium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF22">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="15"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="401" mass="43762" checksum="9D85187C40C9E76F" modified="2007-05-15" version="1">MRRTYAAYDINTRSKPHLNVGTIGHVDHGKTTLTAAITKVMAEIGGAKEIAFDQIDKAPEEKARGITISTSHVEYETATRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLARQVGVPSLVVFMNKVDMVDDEELVELVEMELRELLSFYKFPGDDIPIIKGSALHALKGTEPAIGKDKIVELMKAIDEYIPEPARALDKPFSMPVEDVFSIQGRGTVATGRVEQGIIRTGDDVDVVGITPTKKTTVTGVEMFKKTLNEGQAGDNCGLLLRGLKRDEILRGQVLCKPGSIKPHSKFEAEIYVLKKEEGGRHTPFFSNYRPQFFMRTADITGNITLPEGTEMVMPGDNVTAVFELIHPVAMEPGLRFALREGGRTVGAGVVAKVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY98</accession>
    <name>A4RY98_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418349.1">
        <property type="nucleotide sequence ID" value="XM_001418312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY98"/>
    <dbReference type="STRING" id="436017.A4RY98"/>
    <dbReference type="GeneID" id="5002597"/>
    <dbReference type="Gramene" id="ABO96642">
        <property type="protein sequence ID" value="ABO96642"/>
        <property type="gene ID" value="OSTLU_31950"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31950"/>
    <dbReference type="eggNOG" id="KOG1943">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003043_0_0_1"/>
    <dbReference type="OMA" id="CKALIFE"/>
    <dbReference type="OrthoDB" id="10253476at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058033">
        <property type="entry name" value="ARM_TBCD_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033162">
        <property type="entry name" value="TBCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022577">
        <property type="entry name" value="TBCD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658">
        <property type="entry name" value="BETA-TUBULIN COFACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23579">
        <property type="entry name" value="ARM_TBCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25767">
        <property type="entry name" value="ARM_TBCD_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12612">
        <property type="entry name" value="TFCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin-folding cofactor D ARM repeats" evidence="3">
        <location>
            <begin position="280"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin-folding cofactor D C-terminal" evidence="2">
        <location>
            <begin position="879"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1199" mass="131299" checksum="36D5F6AAACD69823" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYD6</accession>
    <name>A4RYD6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418367.1">
        <property type="nucleotide sequence ID" value="XM_001418330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYD6"/>
    <dbReference type="STRING" id="436017.A4RYD6"/>
    <dbReference type="GeneID" id="5002399"/>
    <dbReference type="Gramene" id="ABO96660">
        <property type="protein sequence ID" value="ABO96660"/>
        <property type="gene ID" value="OSTLU_31991"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31991"/>
    <dbReference type="eggNOG" id="KOG1869">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1104263_0_0_1"/>
    <dbReference type="OMA" id="FKAHQVH"/>
    <dbReference type="OrthoDB" id="10267305at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21372">
        <property type="entry name" value="cwf21_CWC21-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="252" mass="29223" checksum="9E001A15F3989796" modified="2007-05-15" version="1">MRNGVGLASARGSGTSGYVQTNKFHRDASRLTRDAKTNEGWRARDRDGGAGATTTRRPSAAILEHNALRAIEVACAELEERMASEGASEGAIEAAIEKTRRDGRDALRRRRETATKAKSEARDESTHGVMQRKEEEMERLARAFGVDKRERDAREGDAFDRELQQTLREEKRAAREEEERRRARERRRAEKREKKAKKRAKKREKRERKERERREKSKRRGEREAEDAKRNAARFREELDVVDAEIKRRARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYX3</accession>
    <name>A4RYX3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_19560</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418237.1">
        <property type="nucleotide sequence ID" value="XM_001418200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYX3"/>
    <dbReference type="STRING" id="436017.A4RYX3"/>
    <dbReference type="GeneID" id="5002391"/>
    <dbReference type="Gramene" id="ABO96530">
        <property type="protein sequence ID" value="ABO96530"/>
        <property type="gene ID" value="OSTLU_19560"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19560"/>
    <dbReference type="eggNOG" id="KOG2713">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_1_4_1"/>
    <dbReference type="OMA" id="GWGQFKP"/>
    <dbReference type="OrthoDB" id="15808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000002">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050203">
        <property type="entry name" value="Trp-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37672" checksum="5EDBCE7AB566868F" modified="2007-05-15" version="1">MRALRVLSGVQPTGSIHLGNYFGAIKNYVKLQEDYDAFYCVVDLHAITAGGHDPTALEASTRTSAAIYLAAGVSPEKANVFVQSHVPAHSELCWLLNCAAPIGWLEKMIQFKEKARKAGEEVSVGLLDYPVLMAADILLYKADLVPVGEDQRQHLELTRDIAGRVNSLYGGKKWKKRKGGDVLMVPEAFTPKEGGRVMSLTDGTAKMSKSNPAEGSRINVLDTPDEIAKKLKRCKTDAFEGLEFGNPERPEANNLLTMYQLCTGLTQEEVLAECGSMRWGDFKPHLTDAVIAHLSPIQGRYKEIMDEPGYLEDVLKRGAENANEVANLTLRDVRDAMGFVQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ06</accession>
    <name>A4RZ06_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418488.1">
        <property type="nucleotide sequence ID" value="XM_001418451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ06"/>
    <dbReference type="STRING" id="436017.A4RZ06"/>
    <dbReference type="GeneID" id="5002544"/>
    <dbReference type="Gramene" id="ABO96781">
        <property type="protein sequence ID" value="ABO96781"/>
        <property type="gene ID" value="OSTLU_92908"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92908"/>
    <dbReference type="HOGENOM" id="CLU_268376_0_0_1"/>
    <dbReference type="OMA" id="MTWYNRG"/>
    <dbReference type="OrthoDB" id="10438792at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1224" mass="132618" checksum="C5C9A82670B50E9C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZM4</accession>
    <name>A4RZM4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_1178</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418823.1">
        <property type="nucleotide sequence ID" value="XM_001418786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZM4"/>
    <dbReference type="GeneID" id="5002919"/>
    <dbReference type="Gramene" id="ABO97116">
        <property type="protein sequence ID" value="ABO97116"/>
        <property type="gene ID" value="OSTLU_1178"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1178"/>
    <dbReference type="eggNOG" id="KOG1803">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001666_8_2_1"/>
    <dbReference type="OMA" id="TIIHGPP"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd18044">
        <property type="entry name" value="DEXXQc_SMUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048761">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21138">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="152"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="170"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="609" mass="66190" checksum="57B0D75E497B5693" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZS9</accession>
    <name>A4RZS9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418851.1">
        <property type="nucleotide sequence ID" value="XM_001418814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZS9"/>
    <dbReference type="STRING" id="436017.A4RZS9"/>
    <dbReference type="GeneID" id="5002677"/>
    <dbReference type="Gramene" id="ABO97144">
        <property type="protein sequence ID" value="ABO97144"/>
        <property type="gene ID" value="OSTLU_32493"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32493"/>
    <dbReference type="HOGENOM" id="CLU_2444831_0_0_1"/>
    <dbReference type="OrthoDB" id="514292at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="90" mass="10112" checksum="153A8464335E6A96" modified="2007-05-15" version="1">MATLEGAKRAHGTRVPTAEAYEPHLSLAYGVDDAMAREWIREEADAYFREEGLSRGIVVSAISLWETDVEDDSCASWRRVATRELRDAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S055</accession>
    <name>A4S055_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_32622</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418916.1">
        <property type="nucleotide sequence ID" value="XM_001418879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S055"/>
    <dbReference type="STRING" id="436017.A4S055"/>
    <dbReference type="GeneID" id="5002758"/>
    <dbReference type="Gramene" id="ABO97209">
        <property type="protein sequence ID" value="ABO97209"/>
        <property type="gene ID" value="OSTLU_32622"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32622"/>
    <dbReference type="eggNOG" id="KOG0211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015533_2_1_1"/>
    <dbReference type="OMA" id="NTLCMTW"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000062">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="176"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="254"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="4">
        <location>
            <begin position="291"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="332"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="371"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="410"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="498"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="537"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="576"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="603" mass="65532" checksum="ECE4562AC5BA19B8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0B5</accession>
    <name>A4S0B5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosome-releasing factor, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_32681</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418942.1">
        <property type="nucleotide sequence ID" value="XM_001418905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0B5"/>
    <dbReference type="STRING" id="436017.A4S0B5"/>
    <dbReference type="GeneID" id="5002729"/>
    <dbReference type="Gramene" id="ABO97235">
        <property type="protein sequence ID" value="ABO97235"/>
        <property type="gene ID" value="OSTLU_32681"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32681"/>
    <dbReference type="eggNOG" id="KOG4759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073981_2_1_1"/>
    <dbReference type="OMA" id="YVPIPKV"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="7">
        <location>
            <begin position="79"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="25889" checksum="80261E9E3BA11631" modified="2007-05-15" version="1">MRWCLLSMRASTPAAARDVAARSYSKKKKQKQRAAAASDEDGDGDEDGDGDGGEEGDVVEYDAKEWQSKFDAALHALDVDLSQLRTARASAGMIDHIIVDVYGEPTPLSHLGTITAPNAQTLSVTLFDPSTKPSVEKAIVNSPLGFVPKESSDGLIVPIPAMTQDTRKEVCKLASKLGETAKIAARNIRHKAQKRIKRAEMSEDDRKRAEKNLQALTDDIVGKITQRCAAKEKEIMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0H5</accession>
    <name>A4S0H5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lumazine-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_8148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418747.1">
        <property type="nucleotide sequence ID" value="XM_001418710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0H5"/>
    <dbReference type="STRING" id="436017.A4S0H5"/>
    <dbReference type="GeneID" id="5002883"/>
    <dbReference type="KEGG" id="olu:OSTLU_8148"/>
    <dbReference type="eggNOG" id="KOG3310">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_0_1_1"/>
    <dbReference type="OMA" id="IGGHAMS"/>
    <dbReference type="OrthoDB" id="10258924at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000003">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006767">
        <property type="entry name" value="PRK09289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009566">
        <property type="entry name" value="PRK13020.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="4">
        <location>
            <begin position="99"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="99"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="188" mass="20093" checksum="D992AD85188FE954" modified="2007-05-15" version="1" fragment="single">LFTGLVQGKARVESFENLNDEFARLTLRFPGNALEGISLGASVAVNGTCLTVTAVDGDAASFDLIVETLRATNLGKLIVGSEVNYERSARVGDEIGGHTVSGHVHCTAEIVEVVDSEHNRKVVFETSDRALIKYVLPKGFIAIDGCSLTVGDVDKATGRFNVWLIPETLRVTVFGAKSIGDTVNVEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0N3</accession>
    <name>A4S0N3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_35517</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419007.1">
        <property type="nucleotide sequence ID" value="XM_001418970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0N3"/>
    <dbReference type="STRING" id="436017.A4S0N3"/>
    <dbReference type="GeneID" id="5003007"/>
    <dbReference type="Gramene" id="ABO97300">
        <property type="protein sequence ID" value="ABO97300"/>
        <property type="gene ID" value="OSTLU_35517"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35517"/>
    <dbReference type="eggNOG" id="KOG0235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_9_3_1"/>
    <dbReference type="OrthoDB" id="354304at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF10">
        <property type="entry name" value="2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="24585" checksum="F1E5FBD150375258" modified="2007-05-15" version="1" fragment="single">MRTSSSFGAPSRSAASRFVRASSRRSIVARSFDAKAPAPPSTRRAFTFVRHGQSTWNEEGRIQGSSNFSVLTAKGQAQANLTKDVIALDKFDVCLRSPLARARETAEIAWGTRSGTAFVDVDDLREIDLYAFEGLLKEDGMERYGQSYANWKKNPSEFEIDGHYPVRELWDRATRVWNEALLARRETKILVVAHNAVNQALIGSALGLGPEYFRRIVQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Q9</accession>
    <name>A4S0Q9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419022.1">
        <property type="nucleotide sequence ID" value="XM_001418985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Q9"/>
    <dbReference type="STRING" id="436017.A4S0Q9"/>
    <dbReference type="GeneID" id="5002844"/>
    <dbReference type="Gramene" id="ABO97315">
        <property type="protein sequence ID" value="ABO97315"/>
        <property type="gene ID" value="OSTLU_32831"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32831"/>
    <dbReference type="HOGENOM" id="CLU_1463595_0_0_1"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="11"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="20477" checksum="E13F214FDC74ACA5" modified="2007-05-15" version="1">MAASEREVDRTEVYLRYLPRSATEASVRELLKDAGTIERVWMSKDAQGECKGFAFVNFRKNKEARECVLRYNAHPKNYLDGKHVVIEHAKAWDGHAEKKIAACSYGSACAKADCWFSHPADWAFAKTTGTRASGDEKGSGKKRDSGAAVRDGKVRKKVRSKTRLGAKARQRAKKRAEKEAADGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0T3</accession>
    <name>A4S0T3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FBT family transporter: folate/pteridine</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_35682</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419033.1">
        <property type="nucleotide sequence ID" value="XM_001418996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0T3"/>
    <dbReference type="STRING" id="436017.A4S0T3"/>
    <dbReference type="GeneID" id="5002855"/>
    <dbReference type="Gramene" id="ABO97326">
        <property type="protein sequence ID" value="ABO97326"/>
        <property type="gene ID" value="OSTLU_35682"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35682"/>
    <dbReference type="eggNOG" id="ENOG502QRK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_925770_0_0_1"/>
    <dbReference type="OMA" id="IARICTA"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF51">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="292" mass="31678" checksum="6A29D1F5629AC170" modified="2007-05-15" version="1">MCLLLGVVQFLQPENKYVDLAISFGITLVLSVSIYVALPRSIANVTFFLFLTSVLSVSFGSAMSYWFTVDEKCNPGGPHFDYLFFSVYTSIIARICTAIGVYLFQVFFSNANVRVTFWVSAILSSMASISDYCIVKRWNLRVGLSDKAFYLIGDTVLEPMVGMMASMPSMVLMSKMCPENMEATMFAILASFNNLGYSLSSALGVFAMDVAGIKTDLTSGEGGACDFSGLPSLVFYCGMLLPLVSIPLTFVFVPNINMQDVVDLDTGKAVASSADDANEAPTERVPLLAKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0U4</accession>
    <name>A4S0U4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ClpYQ (HslUV)-type protease, proteolytic subunit HSLV (ClpQ)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HslV</name>
        <name evidence="5" type="ORF">OSTLU_10404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418801.1">
        <property type="nucleotide sequence ID" value="XM_001418764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0U4"/>
    <dbReference type="STRING" id="436017.A4S0U4"/>
    <dbReference type="MEROPS" id="T01.006"/>
    <dbReference type="GeneID" id="5002737"/>
    <dbReference type="Gramene" id="ABO97094">
        <property type="protein sequence ID" value="ABO97094"/>
        <property type="gene ID" value="OSTLU_10404"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10404"/>
    <dbReference type="eggNOG" id="ENOG502RS9W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093872_1_0_1"/>
    <dbReference type="OMA" id="WRTDKML"/>
    <dbReference type="OrthoDB" id="276825at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003964">
        <property type="entry name" value="PRK05456.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF7">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0888">Threonine protease</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="200" mass="21258" checksum="F77F1B5C3A59DC93" modified="2007-05-15" version="1" fragment="single">RPARDRASFSAAATSSPHATTVLCVRKDGETVIMADGQVTMGSEIVKPNVKKVRIIEPGVVGGFAGATADAFTLFERLEQQLEQHPGQLTRACVELAKQWRTDKFLRKLEATMIVADKESSFQITGSGDVLEPHDGVIGIGSGGSYALAAARALVDVPGMKAFDIAKKAMTIAADTCVYTNHNFTHQIIGGPDATTKAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S148</accession>
    <name>A4S148_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chlorophyll synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_16384</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419298.1">
        <property type="nucleotide sequence ID" value="XM_001419261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S148"/>
    <dbReference type="STRING" id="436017.A4S148"/>
    <dbReference type="GeneID" id="5003375"/>
    <dbReference type="Gramene" id="ABO97591">
        <property type="protein sequence ID" value="ABO97591"/>
        <property type="gene ID" value="OSTLU_16384"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16384"/>
    <dbReference type="eggNOG" id="ENOG502QQMP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042598_0_0_1"/>
    <dbReference type="OMA" id="QDMYFLR"/>
    <dbReference type="OrthoDB" id="434972at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046408">
        <property type="term" value="F:chlorophyll synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13958">
        <property type="entry name" value="PT_UbiA_chlorophyll"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006372">
        <property type="entry name" value="Chl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011799">
        <property type="entry name" value="ChlG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02056">
        <property type="entry name" value="ChlG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01476">
        <property type="entry name" value="chlor_syn_BchG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005742">
        <property type="entry name" value="PRK07566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35194" checksum="8ADAC4A1170BC594" modified="2007-05-15" version="1">MDASKQLLGFKGAAETDDVWKIRVQLTKPGTWVPLIWGVMCGAAASGHYEWNLDNVGKALLCMTMSGPFLTGYTQTINDWYDREIDAINEPYRPIPSGLISENEVKAQIAVLLVGGWLCALQLDRWCEHDFPIVLALSLFGSYISYIYSAPPLKLKAEGWKGCYALGSSYIALPWWAGMATFGQLTPDVMFLTVLYSIAGLGIAIVNDFKSIEGDRELGLQSLPVAFGIEKAKWITVSTIDITQLFVACYLRAIGEETYSNVLFCLIFPQIFFQFKFFLPDPIKNDVKYQASAQPFLVFGLLTTGLAWGHHINALGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1K8</accession>
    <name>A4S1K8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419167.1">
        <property type="nucleotide sequence ID" value="XM_001419130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1K8"/>
    <dbReference type="STRING" id="436017.A4S1K8"/>
    <dbReference type="GeneID" id="5003452"/>
    <dbReference type="Gramene" id="ABO97460">
        <property type="protein sequence ID" value="ABO97460"/>
        <property type="gene ID" value="OSTLU_16503"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16503"/>
    <dbReference type="HOGENOM" id="CLU_688094_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="401" mass="44599" checksum="2C83774FE672027B" modified="2007-05-15" version="1" fragment="single">MPIGATPRPARATAGRVRVTVRAKASDGDRRAKTGDEKGKKTKTKTKTKSTTGKREGSSGTKKKSSKARTPKGTPFVEKKRIAVKDTYVSPIGELERKLPGRGVWFRKGNATTQDARPDGLGASSKPLLTPGTQAWYKEWKRQRKIDIQNKASRELRKTARKPVEDYAKPGQAAGKPLSIDELKYTALGRAKIQSARQHIAYNRFVHSILNEEIKELYVSVDAVARYAIVYKDGRIAYCQVAPHNTEVYNLTQSVGLEINPTMAEASSHTLAAVGDRGAQIRTFIAGYGVPSLGVFFIWAIVFYMQRFRGDWEDRQKILELERAEEAQRQAEKGDPRINALVEMLQKMDENDPRRDQVKREIRNRKSAIARANGDKKDAAAKAADGDQMGAANAFMRVGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1L6</accession>
    <name>A4S1L6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419172.1">
        <property type="nucleotide sequence ID" value="XM_001419135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1L6"/>
    <dbReference type="GeneID" id="5003457"/>
    <dbReference type="Gramene" id="ABO97465">
        <property type="protein sequence ID" value="ABO97465"/>
        <property type="gene ID" value="OSTLU_93146"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93146"/>
    <dbReference type="HOGENOM" id="CLU_048808_0_0_1"/>
    <dbReference type="OrthoDB" id="10481404at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="366" mass="40216" checksum="6BBCD30B1AF09B71" modified="2007-05-15" version="1">MRDARSLRDAFASTSGFRARGVATADVFTVAQEWLRNHNYVEYLRASALLSPSSDRMDADATPFDAVLRAATGAAPNLVNQDALGDWAEEFAVCHNDVEFDRRWNDLTSGNTGALAGPDRQVGGLPGHVVVTTRDAVWGKSNVGALALSGSEEEKREAVKFLLRMREAAMTYARSRGWTTLGLYFRFFGCEPVGEEERGIIRLHVVNLARAGPRLRRTAKVNLPIDDVIEALGGARASRRGAVLIVSPTLSTTSITPLRRAVEEDSHRSDDDEIEVVIKRVVAAAAAAPPIEIQIPNKLRQQYENVSSNKSKIRMAVRDASEESGFKSLDDAQDEFFRDVSWLSKYKSLSSPARVQLALSEIQLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2R9</accession>
    <name>A4S2R9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419582.1">
        <property type="nucleotide sequence ID" value="XM_001419545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2R9"/>
    <dbReference type="GeneID" id="5003577"/>
    <dbReference type="Gramene" id="ABO97875">
        <property type="protein sequence ID" value="ABO97875"/>
        <property type="gene ID" value="OSTLU_93255"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93255"/>
    <dbReference type="HOGENOM" id="CLU_1350861_0_0_1"/>
    <dbReference type="OMA" id="AMWADED"/>
    <dbReference type="OrthoDB" id="439127at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="203" mass="21838" checksum="9D953C360543F7CC" modified="2007-05-15" version="1">MPTTPTTQTSRVAPRARAPRTASARANARTTRARAGKLVGESWVELSDASYAIENGRELYAAGDVASALKEFERALTLPGSGTKRDRAKPAELSNGERQAALYNIASARCALDDRSGALEALDGCFRAGYANPRAYGAARGMRDLDAMWADEDLTLATRTDEFRAMVKKYKVTPNAMALQFDFNNSIIGGVVGAVSDKMTPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2T5</accession>
    <name>A4S2T5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419592.1">
        <property type="nucleotide sequence ID" value="XM_001419555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2T5"/>
    <dbReference type="STRING" id="436017.A4S2T5"/>
    <dbReference type="GeneID" id="5003753"/>
    <dbReference type="Gramene" id="ABO97885">
        <property type="protein sequence ID" value="ABO97885"/>
        <property type="gene ID" value="OSTLU_33561"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33561"/>
    <dbReference type="HOGENOM" id="CLU_3017640_0_0_1"/>
    <dbReference type="OrthoDB" id="498361at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031985">
        <property type="entry name" value="DUF4787"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35455:SF1">
        <property type="entry name" value="AGAP005842-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35455">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16029">
        <property type="entry name" value="DUF4787"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="56" mass="6456" checksum="BADDED0D8BCC3B05" modified="2007-05-15" version="1">MENCVLRCASASCYDEVYGRDALEEGEVDTERGRAFRSCAREELRRLRGYQTFGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2U4</accession>
    <name>A4S2U4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419807.1">
        <property type="nucleotide sequence ID" value="XM_001419770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2U4"/>
    <dbReference type="GeneID" id="5003809"/>
    <dbReference type="Gramene" id="ABO98100">
        <property type="protein sequence ID" value="ABO98100"/>
        <property type="gene ID" value="OSTLU_33570"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33570"/>
    <dbReference type="HOGENOM" id="CLU_647932_0_0_1"/>
    <dbReference type="OMA" id="HYEQIRR"/>
    <dbReference type="OrthoDB" id="19344at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="424" mass="46451" checksum="0024E4E4BA8C7104" modified="2007-05-15" version="1">MVLASVVEATLGRVAALGRTASSASTSASGVADAGAATLRRLGAAKTRGTSSLDDLNEHAKIITDGVDFRPVTDTSCFVDAYRSSDAATAVMFVFISGCVLGAVPQYLKVVVLGTSEGLSLSSLALMNVSNVCATMNVFILHYEQIRRCVAGAAGYEYERCQASLLTLYYTLIYTLLWIPLYPLAAHFTSDRKTEYFGYVMSKRKAAWYGLALWAVPCALLAAPVARMLFGSTCFEFERYAIFLGLTNAVLETTRYVPQLWESVHSKGSGAMSYMRLALSVAGGLGATIQKAVMHESWSTWGPPLIGHGLEMAIFCVNLFNDMTRRRERTDMRKEALGLMRDSDDDYEDSRDDMETDAHAKRKAAMLESAESAARTGSPTKSESDVEDWVQNIPTEGGFKAKTSFVWHRACTDKHFFTSLVRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3C1</accession>
    <name>A4S3C1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-(apurinic or apyrimidinic site) endonuclease</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_16969</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6 8">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420068.1">
        <property type="nucleotide sequence ID" value="XM_001420031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3C1"/>
    <dbReference type="STRING" id="436017.A4S3C1"/>
    <dbReference type="GeneID" id="5004128"/>
    <dbReference type="Gramene" id="ABO98361">
        <property type="protein sequence ID" value="ABO98361"/>
        <property type="gene ID" value="OSTLU_16969"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16969"/>
    <dbReference type="eggNOG" id="KOG1294">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_613028_0_0_1"/>
    <dbReference type="OMA" id="AFCQFVS"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF10">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 6 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="10">
        <location>
            <begin position="17"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="333"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="7">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="371" mass="42765" checksum="4E966AAF799A7AF9" modified="2007-05-15" version="1">MTEAFTVEDASEPLSFASWNANGLLNRIRDKSDPNGRRTRALLALSENVMRKRPDVIALQEVWLKCEEMGKGTGKWDHAKMGAEDKKLRDEKAFIEALMGRRPFKNYDAYYCLANARRAGVITMVKKCLAKPIRVARTLALDGRDVTPDEIDTNEGRVLMLEYEKMIVLNTYVPHNGSNAERYEKRALWDFRVQRFLENYRGKKDVVWMGDLNVAHQDHDVGPSPRLFEGVGGFTLPERRRFTDILAATDMVDTYRAFNGDRLTYTWRSTRGQGLDGWQGMRLDYFVVPRKLVARIKSCETSTDRFDDTTAQSMPMSCFMDSDHCMIHLSLHKREDDDDEGENEDEDEEENARRAKQQKLDRDADVILISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3G1</accession>
    <name>A4S3G1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peripheral subunit-binding (PSBD) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_4381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420090.1">
        <property type="nucleotide sequence ID" value="XM_001420053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3G1"/>
    <dbReference type="STRING" id="436017.A4S3G1"/>
    <dbReference type="GeneID" id="5004044"/>
    <dbReference type="Gramene" id="ABO98383">
        <property type="protein sequence ID" value="ABO98383"/>
        <property type="gene ID" value="OSTLU_4381"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4381"/>
    <dbReference type="eggNOG" id="KOG0557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_2_0_1"/>
    <dbReference type="OMA" id="HEFMGGS"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="288" mass="30630" checksum="0077A9E62CB0019B" modified="2007-05-15" version="1" fragment="single">PSVRRLCEEHGVDPETLVPGSGPGGHLIAADVLRRVGAVDAATLEKLGLRPPAIARDERPKTLLEDYEYGLARGQRAEDAATTKMRRTIASRLTESKTRTPHAYASADVDLSEVAALRRRVMDASGVKVSVNDCVMYAVGRALREVPELNAGWDDATGGRRAYESVDVCVAVATDDGLITPIVTRADEKTLTEIGADVKGLAKKAREGALKPHEFMGGSFSVSNLGMFGVDAFSAILNPPQGAILAIGAGKDRVVLVEGQPSTVQTMTATVSVDRRVVDEADAARWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3V1</accession>
    <name>A4S3V1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_17102</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IPI1/TEX10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420157.1">
        <property type="nucleotide sequence ID" value="XM_001420120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3V1"/>
    <dbReference type="STRING" id="436017.A4S3V1"/>
    <dbReference type="GeneID" id="5004024"/>
    <dbReference type="Gramene" id="ABO98450">
        <property type="protein sequence ID" value="ABO98450"/>
        <property type="gene ID" value="OSTLU_17102"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17102"/>
    <dbReference type="eggNOG" id="KOG2149">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_302154_0_0_1"/>
    <dbReference type="OMA" id="MFAWFIL"/>
    <dbReference type="OrthoDB" id="361362at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024679">
        <property type="entry name" value="Ipi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057949">
        <property type="entry name" value="TPR_TEX10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056">
        <property type="entry name" value="REGULATOR OF MICROTUBULE DYNAMICS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056:SF2">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12333">
        <property type="entry name" value="Ipi1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25781">
        <property type="entry name" value="TPR_TEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-rRNA-processing protein Ipi1 N-terminal" evidence="6">
        <location>
            <begin position="182"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="TEX10-like TPR repeats" evidence="7">
        <location>
            <begin position="613"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="988" mass="103841" checksum="15A7E2D8704E1964" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S488</accession>
    <name>A4S488_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420049.1">
        <property type="nucleotide sequence ID" value="XM_001420012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S488"/>
    <dbReference type="GeneID" id="5003920"/>
    <dbReference type="Gramene" id="ABO98342">
        <property type="protein sequence ID" value="ABO98342"/>
        <property type="gene ID" value="OSTLU_26325"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26325"/>
    <dbReference type="HOGENOM" id="CLU_1868561_0_0_1"/>
    <dbReference type="OMA" id="GHGVICT"/>
    <dbReference type="OrthoDB" id="342190at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029146">
        <property type="entry name" value="Ten1_animal_plant"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15490">
        <property type="entry name" value="Ten1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="137" mass="14982" checksum="9DC85E5901742DD7" modified="2007-05-15" version="1">MDATIGHGVICTLDECARRAKEADGHEVSIRTLGVLERFDTDTERGTLRATSKSASGADDVHIDVDFSAVRRDEDSAFDGAVRTGSRVCVIGEARRVGDEALFEIRARVVRAMDGLDMRAYGKALEIRRKFLGETPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4B6</accession>
    <name>A4S4B6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_9177</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BBP/SF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420242.1">
        <property type="nucleotide sequence ID" value="XM_001420205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4B6"/>
    <dbReference type="STRING" id="436017.A4S4B6"/>
    <dbReference type="GeneID" id="5004308"/>
    <dbReference type="Gramene" id="ABO98535">
        <property type="protein sequence ID" value="ABO98535"/>
        <property type="gene ID" value="OSTLU_9177"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9177"/>
    <dbReference type="eggNOG" id="KOG0119">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065679_2_1_1"/>
    <dbReference type="OrthoDB" id="497369at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045131">
        <property type="term" value="F:pre-mRNA branch point binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02395">
        <property type="entry name" value="KH-I_BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="KHDC4/BBP-like KH-domain type I" evidence="4">
        <location>
            <begin position="8"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="113" mass="12882" checksum="04EB0D603EC915EF" modified="2007-05-15" version="1" fragment="single">KLYVPEDEYPGYNFIGLILGPRGNTQKRMERETNTRIMLRGKGSVKPGAHRDHKTDYKEDEPLHVVILGETWEGVDAAAEMVGHILRPIDEEANVHKRMQLRELASINGTFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4K2</accession>
    <name>A4S4K2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">spermidine synthase</fullName>
            <ecNumber evidence="3">2.5.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SPD1</name>
        <name evidence="10" type="ORF">OSTLU_26437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO98745"/>
        <property type="gene ID" value="OSTLU_26437"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26437"/>
    <dbReference type="eggNOG" id="KOG1562">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_048199_3_0_1"/>
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    <dbReference type="OrthoDB" id="38125at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000013">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030668">
        <property type="entry name" value="Spermi_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000502">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="9">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="34963" checksum="AB85F0B451E207E4" modified="2007-05-15" version="1">MNKYADDAPQSADKCIGACGEGWLCEVSEMWKGQAMSLKIDEELFRGRSEFQDVYVFKNSAYGNVLVLDGVIQATERDEFAYQEMITHLPLCALNEEPKRVLVVGGGDGGVLREVTRHGSIERIEIAEIDGMVVEMSKKFLPSMAVGFDDARVEVNICDGIKYVGDAEEGTYDAIIVDSSDPIGPASVLFEEAFFKKMHRALKPGGVVCTQAECVWLHIDLIEDLAKMCKGIFVGGSMAYGYTTIPTYPSGQIGFMMCSKPAADGSTVDFTKAKRFPRPADESALKPMRYYNPQVHAAAFVLPEFARAALEPHLVPGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4T4</accession>
    <name>A4S4T4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7067 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420322.1">
        <property type="nucleotide sequence ID" value="XM_001420285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4T4"/>
    <dbReference type="GeneID" id="5004379"/>
    <dbReference type="Gramene" id="ABO98615">
        <property type="protein sequence ID" value="ABO98615"/>
        <property type="gene ID" value="OSTLU_26521"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26521"/>
    <dbReference type="HOGENOM" id="CLU_505654_0_0_1"/>
    <dbReference type="OMA" id="VRAYVRW"/>
    <dbReference type="OrthoDB" id="498982at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055495">
        <property type="entry name" value="CWD_DUF7067"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23229">
        <property type="entry name" value="DUF7067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7067" evidence="3">
        <location>
            <begin position="73"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="279"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="547" mass="59958" checksum="36B49C3577B904CB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4V0</accession>
    <name>A4S4V0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420329.1">
        <property type="nucleotide sequence ID" value="XM_001420292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4V0"/>
    <dbReference type="GeneID" id="5004388"/>
    <dbReference type="Gramene" id="ABO98622">
        <property type="protein sequence ID" value="ABO98622"/>
        <property type="gene ID" value="OSTLU_26537"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26537"/>
    <dbReference type="eggNOG" id="ENOG502S3NP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_507622_0_0_1"/>
    <dbReference type="OMA" id="DAINDCH"/>
    <dbReference type="OrthoDB" id="41870at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011643">
        <property type="entry name" value="HCR1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07692">
        <property type="entry name" value="Fea1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672147" evidence="2">
        <location>
            <begin position="29"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="507"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="556" mass="59578" checksum="B9111E6386C2B821" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5D6</accession>
    <name>A4S5D6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93512</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420756.1">
        <property type="nucleotide sequence ID" value="XM_001420719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5D6"/>
    <dbReference type="GeneID" id="5004825"/>
    <dbReference type="Gramene" id="ABO99049">
        <property type="protein sequence ID" value="ABO99049"/>
        <property type="gene ID" value="OSTLU_93512"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93512"/>
    <dbReference type="HOGENOM" id="CLU_1035836_0_0_1"/>
    <dbReference type="OMA" id="LWHCPEV"/>
    <dbReference type="OrthoDB" id="10384976at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="269" mass="30771" checksum="97C49B6D1738F6FF" modified="2007-05-15" version="1">MNDFARRAASRAVFASTRDRGRRRARRRARWRARSARDAQGGANFERLIRRNEWLFPQPERDDEREALDAFWLAKGARDERQRARLVAMGRELASGVAERELYGDADALGHATRRLEAMFPRGTDVAKMLWHCPEVLQLPLSEVARRLIALKRAFPRVNAERVLEGNPRALLMDDLSVVADAVDELQLEFPRVDMVAVIEFEPHVIQRALPARVRALKSIKPCDRSASLRAFYPPRVDDPPSFEPMKNAQLFAKVFLLTTECSFPRGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Q7</accession>
    <name>A4S5Q7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_4881</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420651.1">
        <property type="nucleotide sequence ID" value="XM_001420614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Q7"/>
    <dbReference type="STRING" id="436017.A4S5Q7"/>
    <dbReference type="GeneID" id="5004769"/>
    <dbReference type="Gramene" id="ABO98944">
        <property type="protein sequence ID" value="ABO98944"/>
        <property type="gene ID" value="OSTLU_4881"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4881"/>
    <dbReference type="eggNOG" id="KOG1528">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033446_2_1_1"/>
    <dbReference type="OMA" id="ETHNRNC"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="318" mass="33356" checksum="9FDEDE584E7C3186" modified="2007-05-15" version="1" fragment="single">AARAVRLAGALCRKMQFELRTNEKVSKSDDSPVTVADFAAQAVVSHVLGVARPDVGLVAEEDARSMREPAGAKLRARVTAVVNDALEGVVERRLSEEEVMDAIDRGATDGGASGSFWILDPIDGTKGFINGRQYAIALALMEDGEVTGGVLGCPNMPSEKIPRGATEIPTAAPGVIFVAYKGRGTTVGAFDAEHPLRDGAKITTNKVASSSEATYMESWGDSIVADHGFTNSLSAAMGVTAPPVRIDSMAKYGALARGDTNMYLRFPPASYREKVWDHAAGAIVVQEAGGVITDGAGNPLDFSKGRFLDIDIGIVATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5S8</accession>
    <name>A4S5S8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PLAC8 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420824.1">
        <property type="nucleotide sequence ID" value="XM_001420787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5S8"/>
    <dbReference type="GeneID" id="5004780"/>
    <dbReference type="Gramene" id="ABO99117">
        <property type="protein sequence ID" value="ABO99117"/>
        <property type="gene ID" value="OSTLU_26870"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26870"/>
    <dbReference type="HOGENOM" id="CLU_1941610_0_0_1"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="13653" checksum="3629831524FD77F6" modified="2007-05-15" version="1">MNNQLFGCTDDVGDCLYACCCGPCHVGTIAQRTGSGDCFGTCCINYIAYMFCCPLGLVHGGSVFKSALYRVGVTAPLDTIACICCHPCLQCQVSREINDRQAAAAANPQAGAPQPQVIVVQAPPAQVVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5W6</accession>
    <name>A4S5W6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420681.1">
        <property type="nucleotide sequence ID" value="XM_001420644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5W6"/>
    <dbReference type="STRING" id="436017.A4S5W6"/>
    <dbReference type="GeneID" id="5004882"/>
    <dbReference type="Gramene" id="ABO98974">
        <property type="protein sequence ID" value="ABO98974"/>
        <property type="gene ID" value="OSTLU_93554"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93554"/>
    <dbReference type="HOGENOM" id="CLU_2216723_0_0_1"/>
    <dbReference type="OrthoDB" id="268593at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11271" checksum="82D9907EB9D78B4E" modified="2007-05-15" version="1" fragment="single">VTVMRDGVRATIDAREGETLASALARDATMKSAVPVMSIDRGPDAHVVIPDAFLKRLPALDALEMDKLEDVAAGLGANSRLASQVTLTKEVDGLVAAIAKVYPENPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6C3</accession>
    <name>A4S6C3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420917.1">
        <property type="nucleotide sequence ID" value="XM_001420880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6C3"/>
    <dbReference type="STRING" id="436017.A4S6C3"/>
    <dbReference type="GeneID" id="5005123"/>
    <dbReference type="Gramene" id="ABO99210">
        <property type="protein sequence ID" value="ABO99210"/>
        <property type="gene ID" value="OSTLU_27067"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27067"/>
    <dbReference type="eggNOG" id="KOG4306">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_772406_0_0_1"/>
    <dbReference type="OMA" id="WANTQSC"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="1">
        <location>
            <begin position="62"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="334" mass="36487" checksum="148633A72D25CD85" modified="2007-05-15" version="1">MNATRDRALGALTLPGSHDSATQYLSPKLQPGRAGQLPRWVDDAVRLAESIGVPADQLVRRWARAQSARVGAQLRLGARYVDLRSGWDGDEGVWRAHHALEGQAVDEILEEVKVFLVEQPSEVVIVELSHFYGDPSESAVERLATAATEIFGDMLAPYPGDARAALYDAQLGKDYVDVNHRAIVVFEDANVGKRFKLWPRETLTNTYADSDDARAMAAFNRDVVAAFNEKSFRDDALLKLSWTLTPQASTVVRSLNIFEKNPKSLLELASSRANPPLRDFAADAALHACSLAHIVVVDDFDHSSVVDIVLASNVHGMFPKGACAWSAAALASER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6V7</accession>
    <name>A4S6V7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17931</name>
        <name evidence="4" type="ORF">OSTLU_19178</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421160.1">
        <property type="nucleotide sequence ID" value="XM_001421123.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422795.1">
        <property type="nucleotide sequence ID" value="XM_001422758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6V7"/>
    <dbReference type="STRING" id="436017.A4S6V7"/>
    <dbReference type="GeneID" id="5005218"/>
    <dbReference type="GeneID" id="5006943"/>
    <dbReference type="Gramene" id="ABO99453">
        <property type="protein sequence ID" value="ABO99453"/>
        <property type="gene ID" value="OSTLU_17931"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01154">
        <property type="protein sequence ID" value="ABP01154"/>
        <property type="gene ID" value="OSTLU_19178"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17931"/>
    <dbReference type="KEGG" id="olu:OSTLU_19178"/>
    <dbReference type="HOGENOM" id="CLU_1002529_0_0_1"/>
    <dbReference type="OrthoDB" id="500567at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="31130" checksum="0B773D9F22342A2C" modified="2007-05-15" version="1">MLAAERVKVVEAHSAGKIAQDALREQLTKSENETMALRRMMETRSTEMANAVRQLNEELAAQHEIVERGMASRVDALRETFDDELARARERANEMIESARKSVKEANERVARMESTATRAENVSRNALMKLKEIAAASADTERECAQLRTNLHAVGEINAKLTRRIIDGEPFVLDEELDVVREPGAEMSVNTPSPASERSRGKPAKFDTRDIQHIHRELQNELSKLRVEHESIAREIGGSSGAEGEFLAKALEDAQERVESKARQVKLLNKTIRSATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Y3</accession>
    <name>A4S6Y3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_17952</name>
        <name evidence="5" type="ORF">OSTLU_36663</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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            <end position="176"/>
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        <source>
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            <dbReference type="PROSITE" id="PS51186"/>
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        <source>
            <dbReference type="EMBL" id="ABO99315.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP01233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="21436" checksum="A94E6493235DF95A" modified="2007-05-15" version="1">MSRDAVDGVATPVRFASLTDATERDLRALNAVLFPVRYGDAFYDDCRRAGGCTQLAYAMDERGSGSATTTTMTLAGAIACRLEMNAASDGAKLYIMTLGVYAGRRDGKIGSRLLTHALNVASRDAFVKEAYLHVQTNNFQAFEFYERFGFEKGEVVKNYYKRIEPPDAVILRRDLGASWTERELEGVTFDEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S733</accession>
    <name>A4S733_OSTLU</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25467</name>
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    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
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            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome 14"/>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
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        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="524"/>
        </location>
    </feature>
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        <location>
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        </location>
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    </feature>
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            <end position="581"/>
        </location>
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        <location>
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        </location>
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    </feature>
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        </location>
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        <location>
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        </location>
    </feature>
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        </location>
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            <begin position="1035"/>
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        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1089" mass="118611" checksum="A3D3436317CC4549" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="4">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="5" type="ORF">OSTLU_2772</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Gramene" id="ABO99787">
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        <property type="gene ID" value="OSTLU_2772"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004017_8_5_1"/>
    <dbReference type="OMA" id="HITRILH"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Pumilio homolog 9"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="PUM-HD"/>
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    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF13">
        <property type="entry name" value="PUMILIO HOMOLOGY DOMAIN FAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
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        <property type="match status" value="8"/>
    </dbReference>
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        <property type="match status" value="8"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="6"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="34"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="78"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="117"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="153"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="225"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="264"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="326"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99787.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="326" mass="36573" checksum="7D2A0B6EB5C5F152" modified="2007-05-15" version="1" fragment="single">GQISVLARDQHGCRFLQRKFDEEGAKAVDLCYDEIIAEAVELMMDPFGNYLVQKLIECCSDEQRSGVLRAVSVVKDDSLDGLPELVTIALNTHGTRAVQKLIEMLNSPEEVSLATNALRPGVVTLIKDLNGNHVIQRCLQRLSSEDNQFIYDAAKVHCVEIATHRHGCCVLQRCIDHAIDEQRRPLVLEIASQALVLSQDPFGNYVVQYILDLGLSWANGEVMTQLLGNYAELSMQKFSSNVVEKCLKLADASLEKNRNTVVREIMQSPLLDRLLMDPYGNYVVQSTLTVTKGVLHTELVERIRPHLPLIKNSPFGKRILRLLLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7R0</accession>
    <name>A4S7R0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421315.1">
        <property type="nucleotide sequence ID" value="XM_001421278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7R0"/>
    <dbReference type="STRING" id="436017.A4S7R0"/>
    <dbReference type="GeneID" id="5005291"/>
    <dbReference type="Gramene" id="ABO99608">
        <property type="protein sequence ID" value="ABO99608"/>
        <property type="gene ID" value="OSTLU_93726"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93726"/>
    <dbReference type="eggNOG" id="ENOG502SZNG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_381483_0_0_1"/>
    <dbReference type="OMA" id="ETMRHNE"/>
    <dbReference type="OrthoDB" id="10492446at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="126"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="518"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="726" mass="79879" checksum="E4407C2A260A7A8C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7W7</accession>
    <name>A4S7W7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear condensin complex subunit 3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CPG3501</name>
        <name evidence="10" type="ORF">OSTLU_25561</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421348.1">
        <property type="nucleotide sequence ID" value="XM_001421311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7W7"/>
    <dbReference type="STRING" id="436017.A4S7W7"/>
    <dbReference type="GeneID" id="5005432"/>
    <dbReference type="Gramene" id="ABO99641">
        <property type="protein sequence ID" value="ABO99641"/>
        <property type="gene ID" value="OSTLU_25561"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25561"/>
    <dbReference type="eggNOG" id="KOG2025">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_300031_0_0_1"/>
    <dbReference type="OMA" id="CAKSARM"/>
    <dbReference type="OrthoDB" id="496423at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="476"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="852"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="909"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="929"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="962" mass="102991" checksum="B0233A5A4CD60252" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S822</accession>
    <name>A4S822_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421552.1">
        <property type="nucleotide sequence ID" value="XM_001421515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S822"/>
    <dbReference type="STRING" id="436017.A4S822"/>
    <dbReference type="GeneID" id="5005656"/>
    <dbReference type="Gramene" id="ABO99845">
        <property type="protein sequence ID" value="ABO99845"/>
        <property type="gene ID" value="OSTLU_27700"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27700"/>
    <dbReference type="eggNOG" id="KOG0211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012754_0_0_1"/>
    <dbReference type="OMA" id="PMISRAC"/>
    <dbReference type="OrthoDB" id="1695393at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032367">
        <property type="term" value="P:intracellular cholesterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040362">
        <property type="entry name" value="RELCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32059">
        <property type="entry name" value="RAB11-BINDING PROTEIN RELCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32059:SF0">
        <property type="entry name" value="RAB11-BINDING PROTEIN RELCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="926"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="220"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="932"/>
            <end position="941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="975" mass="104545" checksum="501555E23B8B8F9B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4S831</accession>
    <name>A4S831_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_27708</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421558.1">
        <property type="nucleotide sequence ID" value="XM_001421521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S831"/>
    <dbReference type="STRING" id="436017.A4S831"/>
    <dbReference type="GeneID" id="5005662"/>
    <dbReference type="Gramene" id="ABO99851">
        <property type="protein sequence ID" value="ABO99851"/>
        <property type="gene ID" value="OSTLU_27708"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27708"/>
    <dbReference type="eggNOG" id="KOG2323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015439_0_1_1"/>
    <dbReference type="OMA" id="TIMADIC"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="16">
        <location>
            <begin position="40"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="17">
        <location>
            <begin position="399"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO99851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="527" mass="56721" checksum="B6842A34691649BD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S849</accession>
    <name>A4S849_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421563.1">
        <property type="nucleotide sequence ID" value="XM_001421526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S849"/>
    <dbReference type="GeneID" id="5005839"/>
    <dbReference type="Gramene" id="ABO99856">
        <property type="protein sequence ID" value="ABO99856"/>
        <property type="gene ID" value="OSTLU_18276"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18276"/>
    <dbReference type="eggNOG" id="ENOG502RV7A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045619_0_0_1"/>
    <dbReference type="OrthoDB" id="2019752at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="401" mass="44099" checksum="2CBEB341D114D5BF" modified="2007-05-15" version="1">MEATEAEAYATLRDAERAALEVEVPCAMAEVEHEFRAVSAARALETRRAMVRLRALLPVRIDEERGSREAPRGVRACEWRVPDAIDDRGFDAHELAAGLGALMHFSALASRYLDAPRLHRGSHAASQSYVWAPTSAWDDVDSSVWENKGTVHVRDFAGVNSERLELFLPRAVVEGSCDPASVRESRLRLKRAIRLLTRSVSVMCAHQSRECGVIAPPNWGPFSQLCALTSAVAKGEETTTTAPQRAPARRQTPPQILRTSTNDRRRESVESFESRDMVQPVTDGAHRGDVVKRAVSSTIAEISRNHWFSAHASTPRESNAIVDDDELLFETLNAGDFFIDHDSVDDIGGWEAIHGNRLRPAAVEDAVAPVSNRGLVLPPPPSAVDDIEHWERAMLVDNAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8D7</accession>
    <name>A4S8D7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable 6-phosphogluconolactonase</fullName>
            <ecNumber evidence="5">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_13316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421751.1">
        <property type="nucleotide sequence ID" value="XM_001421714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8D7"/>
    <dbReference type="STRING" id="436017.A4S8D7"/>
    <dbReference type="GeneID" id="5005640"/>
    <dbReference type="Gramene" id="ABP00045">
        <property type="protein sequence ID" value="ABP00045"/>
        <property type="gene ID" value="OSTLU_13316"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13316"/>
    <dbReference type="eggNOG" id="KOG3147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053947_0_2_1"/>
    <dbReference type="OMA" id="YDKIVDW"/>
    <dbReference type="OrthoDB" id="432544at2759"/>
    <dbReference type="UniPathway" id="UPA00115"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000005">
        <property type="entry name" value="6-phosphogluconolactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF0">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="248" mass="27171" checksum="952CE52F6EA8472E" modified="2007-05-15" version="1">MERVRDNDACAKALADAVETASREAIEKRGTFAVALAGGSLAKALGALREETRRVEWDKWRVFWVDERCVKWDDEESNFGGAMRALFGDVSVKRERLYAVDETLCERNEGAAKPCAEAYERDLRALTPDVIELNEDGLPVFDMLLLGFGPDGHICSLFPNHALLRETEGWILPIADSPKPPPERVTFSLPLVNAARAKVFVASGAGKAEMTARILEEAPQDGSVPAALVTGDVRWIVDDAAASKMRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8G7</accession>
    <name>A4S8G7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kish</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_40704</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in the early part of the secretory pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the KISH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421618.1">
        <property type="nucleotide sequence ID" value="XM_001421581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8G7"/>
    <dbReference type="STRING" id="436017.A4S8G7"/>
    <dbReference type="GeneID" id="5005727"/>
    <dbReference type="Gramene" id="ABO99911">
        <property type="protein sequence ID" value="ABO99911"/>
        <property type="gene ID" value="OSTLU_40704"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40704"/>
    <dbReference type="eggNOG" id="KOG3808">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152663_1_1_1"/>
    <dbReference type="OMA" id="KVGFQGT"/>
    <dbReference type="OrthoDB" id="10034655at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051523">
        <property type="entry name" value="KISH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009653">
        <property type="entry name" value="Ksh1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13229">
        <property type="entry name" value="PROTEIN KISH-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06842">
        <property type="entry name" value="DUF1242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU910717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="72" mass="8140" checksum="B9F14B20BCB923D1" modified="2007-05-15" version="1">MSALFDFKSFLTTLLLFICACTYVKLRAPGLLDSHRTGFRGVFWKAARVGERLSPWVSVACAYMSVQTLFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8I7</accession>
    <name>A4S8I7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_18379</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-C/MIF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421773.1">
        <property type="nucleotide sequence ID" value="XM_001421736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8I7"/>
    <dbReference type="GeneID" id="5005739"/>
    <dbReference type="Gramene" id="ABP00067">
        <property type="protein sequence ID" value="ABP00067"/>
        <property type="gene ID" value="OSTLU_18379"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18379"/>
    <dbReference type="eggNOG" id="ENOG502SEFK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_407357_0_0_1"/>
    <dbReference type="OMA" id="ANPIWPR"/>
    <dbReference type="OrthoDB" id="1939643at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019237">
        <property type="term" value="F:centromeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051455">
        <property type="term" value="P:spindle attachment to meiosis I kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028386">
        <property type="entry name" value="CENP-C/Mif2/cnp3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684:SF11">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
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        </location>
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        </location>
    </feature>
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            <end position="469"/>
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        </location>
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</entry>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
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                <person name="Ren Q."/>
                <person name="Paulsen I."/>
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                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
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                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
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            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421967.1">
        <property type="nucleotide sequence ID" value="XM_001421930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8X8"/>
    <dbReference type="GeneID" id="5006127"/>
    <dbReference type="Gramene" id="ABP00261">
        <property type="protein sequence ID" value="ABP00261"/>
        <property type="gene ID" value="OSTLU_28003"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28003"/>
    <dbReference type="HOGENOM" id="CLU_426668_0_0_1"/>
    <dbReference type="OrthoDB" id="10410376at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="509"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="642" mass="70042" checksum="833BD0E762FA8D89" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9B0</accession>
    <name>A4S9B0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_5580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421904.1">
        <property type="nucleotide sequence ID" value="XM_001421867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9B0"/>
    <dbReference type="STRING" id="436017.A4S9B0"/>
    <dbReference type="GeneID" id="5006072"/>
    <dbReference type="Gramene" id="ABP00198">
        <property type="protein sequence ID" value="ABP00198"/>
        <property type="gene ID" value="OSTLU_5580"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5580"/>
    <dbReference type="eggNOG" id="KOG4750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_0_1_1"/>
    <dbReference type="OMA" id="DVIMHDR"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000002">
        <property type="entry name" value="Serine acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="entry name" value="serine acetyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053376">
        <property type="entry name" value="Serine_acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041874">
        <property type="entry name" value="EPS_EpsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42811">
        <property type="entry name" value="SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00971">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine acetyltransferase N-terminal" evidence="7">
        <location>
            <begin position="7"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="265" mass="28426" checksum="DB74686356634FD2" modified="2007-05-15" version="1" fragment="single">DEAVDYIWTAIREEARRDAAREPMLSSSLYASVLSHDTLEQSLSFVLANKLADSTLLPTQLMEIFNTVLTEEEETAAGAELREAVRADVAAFKERDPACVGYSHALLLFKGFHALESHRIQHALWNRGQRLMALAMQSRISAVFSMDIHPAARLGKGILIDHGTGVVIGETCVIGDSVSILQGVTLGGTGKAVGDRHPKIESHVLIGAHSTVLGNIKVERGSMISAGSLVLKPVAAHTMVAGSPAKVVGKVRDSKPSLVMDHHIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9K3</accession>
    <name>A4S9K3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HELP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_42170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat EMAP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422083.1">
        <property type="nucleotide sequence ID" value="XM_001422046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9K3"/>
    <dbReference type="STRING" id="436017.A4S9K3"/>
    <dbReference type="GeneID" id="5006141"/>
    <dbReference type="Gramene" id="ABP00400">
        <property type="protein sequence ID" value="ABP00400"/>
        <property type="gene ID" value="OSTLU_42170"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42170"/>
    <dbReference type="eggNOG" id="KOG2106">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011754_2_0_1"/>
    <dbReference type="OrthoDB" id="47802at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000320">
        <property type="entry name" value="echinoderm microtubule-associated protein-like 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055439">
        <property type="entry name" value="Beta-prop_EML_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005108">
        <property type="entry name" value="HELP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF33">
        <property type="entry name" value="HELP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23409">
        <property type="entry name" value="Beta-prop_EML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03451">
        <property type="entry name" value="HELP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EML-like first beta-propeller" evidence="5">
        <location>
            <begin position="98"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="EML-like second beta-propeller" evidence="6">
        <location>
            <begin position="363"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="482"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="627" mass="69859" checksum="6781AF3AD8A5414D" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9K5</accession>
    <name>A4S9K5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422185.1">
        <property type="nucleotide sequence ID" value="XM_001422148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9K5"/>
    <dbReference type="GeneID" id="5006143"/>
    <dbReference type="Gramene" id="ABP00502">
        <property type="protein sequence ID" value="ABP00502"/>
        <property type="gene ID" value="OSTLU_28233"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28233"/>
    <dbReference type="HOGENOM" id="CLU_2254678_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="104" mass="11402" checksum="E729785512BFF517" modified="2007-05-15" version="1">MPDINQCWVNQYPSLTCLAGTFHRVVFHSSPLDADANSHETFTPGGAASINRRARPKSRATTEACVVLRSGFQILGCVSLSCTDIFELFSSRAPLPRFPELCVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Z6</accession>
    <name>A4S9Z6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422258.1">
        <property type="nucleotide sequence ID" value="XM_001422221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9Z6"/>
    <dbReference type="GeneID" id="5006315"/>
    <dbReference type="Gramene" id="ABP00575">
        <property type="protein sequence ID" value="ABP00575"/>
        <property type="gene ID" value="OSTLU_28372"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28372"/>
    <dbReference type="HOGENOM" id="CLU_2502020_0_0_1"/>
    <dbReference type="OrthoDB" id="10450613at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="86" mass="9302" checksum="9F069914E218637B" modified="2007-05-15" version="1">MFALVTSSAAVRANAPAQFKRNVSARAGFKDSVAGKSNWNAYEGSDEKTLSPEELRAKNAAEEKEIQARRAAAAKKMEEERKAAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA74</accession>
    <name>A4SA74_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422332.1">
        <property type="nucleotide sequence ID" value="XM_001422295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA74"/>
    <dbReference type="GeneID" id="5006389"/>
    <dbReference type="Gramene" id="ABP00649">
        <property type="protein sequence ID" value="ABP00649"/>
        <property type="gene ID" value="OSTLU_18809"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18809"/>
    <dbReference type="HOGENOM" id="CLU_1613560_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="2">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18925" checksum="A68E06C79EBA836F" modified="2007-05-15" version="1">MPTGCVYEMFSDNAKCDKTYIGSTTGSLRARLASHKYARHPIFTFGDADVRVLEKDIPAGELHQRKSAYMREKRDGLFNSRAAGRSQKHACHENVDESQAYSRAQYTPKRDGGDGNYRQLNYYKQHAKRILRKTCLKNARARGTLPSKRSLDKYQFTLDELRDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA78</accession>
    <name>A4SA78_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422335.1">
        <property type="nucleotide sequence ID" value="XM_001422298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA78"/>
    <dbReference type="GeneID" id="5006353"/>
    <dbReference type="Gramene" id="ABP00652">
        <property type="protein sequence ID" value="ABP00652"/>
        <property type="gene ID" value="OSTLU_18813"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18813"/>
    <dbReference type="HOGENOM" id="CLU_1279495_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673282" evidence="2">
        <location>
            <begin position="22"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="216" mass="22450" checksum="ED1CA080920F075B" modified="2007-05-15" version="1">MFKNLLVPFVFGLAVAHTARADAGDTCSTHTDCVVSSGYASANPWASSEEFCYNTGTYNGVTVGVCSDCFGCSAGPPPYGNSIDQSCPSKCTDTISSYTSCGTEIATEVANGAKCWDGAHGCPPLHKKGGKWCSMYTGGQNVCCGDDCCKPDGGAIAGIIIGTVVGLTLLIVSCCYCGRCGCFAYRRDQLIATAVATRPQQPQVIYVQQAPAKVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAA1</accession>
    <name>A4SAA1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-glucose/GDP-mannose dehydrogenase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422348.1">
        <property type="nucleotide sequence ID" value="XM_001422311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAA1"/>
    <dbReference type="STRING" id="436017.A4SAA1"/>
    <dbReference type="GeneID" id="5006354"/>
    <dbReference type="Gramene" id="ABP00665">
        <property type="protein sequence ID" value="ABP00665"/>
        <property type="gene ID" value="OSTLU_28491"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28491"/>
    <dbReference type="HOGENOM" id="CLU_1311965_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43750:SF2">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43750">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE TUAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase N-terminal" evidence="1">
        <location>
            <begin position="15"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="210" mass="23487" checksum="E2008CBD7E26050A" modified="2007-05-15" version="1">MATTRSILQTTRARFVGLGRLGLCTALKCEQADWDIVGSDVFPAHVDSINEITLRLTEPRVEEALRSSKHLRATLKLREVIDRVDMVFILVATPTDSGDQAYDTSALKQTLDDLRHGVTWLDLDRCKVSYVAYESNCPVDIIEESQLLEIAKRLVRRGKKVTVFDRVAIVHLVRGTYGQLFDYEICDTTAGGVAPIPNTTMENPLSSYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAG0</accession>
    <name>A4SAG0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_18871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leguminous lectin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422428.1">
        <property type="nucleotide sequence ID" value="XM_001422391.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4SAG0"/>
    <dbReference type="GeneID" id="5006439"/>
    <dbReference type="Gramene" id="ABP00745">
        <property type="protein sequence ID" value="ABP00745"/>
        <property type="gene ID" value="OSTLU_18871"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18871"/>
    <dbReference type="HOGENOM" id="CLU_248441_0_0_1"/>
    <dbReference type="OMA" id="WINATEY"/>
    <dbReference type="OrthoDB" id="497379at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019825">
        <property type="entry name" value="Lectin_legB_Mn/Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050258">
        <property type="entry name" value="Leguminous_Lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32401">
        <property type="entry name" value="CONCANAVALIN A-LIKE LECTIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32401:SF48">
        <property type="entry name" value="LEGUME LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00307">
        <property type="entry name" value="LECTIN_LEGUME_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1387"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1500"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1573"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1500"/>
            <end position="1513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1682" mass="183287" checksum="E37029456F852ED5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAH2</accession>
    <name>A4SAH2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_9119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422388.1">
        <property type="nucleotide sequence ID" value="XM_001422351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAH2"/>
    <dbReference type="STRING" id="436017.A4SAH2"/>
    <dbReference type="GeneID" id="5006490"/>
    <dbReference type="KEGG" id="olu:OSTLU_9119"/>
    <dbReference type="eggNOG" id="KOG1698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103507_2_0_1"/>
    <dbReference type="OMA" id="TITVYYE"/>
    <dbReference type="OrthoDB" id="432645at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_bL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="Ribosomal_bL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680:SF9">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12919" checksum="F43116BFE6FE972C" modified="2007-05-15" version="1" fragment="single">LSAYVERASARQTKRDLIPFRVGMTLRVGVTVKEGNKTRVQPFEGVVIGIHRAGVATTVTVRKTLQGFGVERVFPVHSPLCTDLFFIFSAQVRRAKLFYLRRLVGKQARLKTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBC6</accession>
    <name>A4SBC6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_43411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422753.1">
        <property type="nucleotide sequence ID" value="XM_001422716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBC6"/>
    <dbReference type="GeneID" id="5006651"/>
    <dbReference type="Gramene" id="ABP01070">
        <property type="protein sequence ID" value="ABP01070"/>
        <property type="gene ID" value="OSTLU_43411"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43411"/>
    <dbReference type="eggNOG" id="ENOG502QSQK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038878_1_0_1"/>
    <dbReference type="OMA" id="KQCFACR"/>
    <dbReference type="OrthoDB" id="498636at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
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        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
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        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF6">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="81"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="279" mass="31444" checksum="D0B833156402B27E" modified="2007-05-15" version="1">MNAFLSFLEREPDLEQALYGVDYKLEPGCAHCFETLSVRVVDELCPFGEVNLGVDGECVQSLTPEEWAAEVRSRDTTKSSLLDVRNFYESRLGHFFGSTCAPIRRFSQFKEWLARDGVLEREIKDKDLYIFCTGGVRCEKVATYLTTRLPEGSRPRTVRKLAGGIVAYAKSGINERDGLFKGSNYVFDARGSTPVGQDLPSTSWCDGCGDASGRISKCVGKSCHVILIACERCGDTVYCCTSCRDQTERARLDEDNFRRRACECDSFESRERRLRHAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQF7</accession>
    <name>A4RQF7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415378.1">
        <property type="nucleotide sequence ID" value="XM_001415341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQF7"/>
    <dbReference type="GeneID" id="4999511"/>
    <dbReference type="Gramene" id="ABO93670">
        <property type="protein sequence ID" value="ABO93670"/>
        <property type="gene ID" value="OSTLU_92053"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92053"/>
    <dbReference type="HOGENOM" id="CLU_365778_0_0_1"/>
    <dbReference type="OMA" id="YVERETN"/>
    <dbReference type="OrthoDB" id="10562595at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044230">
        <property type="entry name" value="GTF3C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="773" mass="83263" checksum="D35E059B7630D01C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQN4</accession>
    <name>A4RQN4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_86040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415417.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQN4"/>
    <dbReference type="STRING" id="436017.A4RQN4"/>
    <dbReference type="GeneID" id="4999876"/>
    <dbReference type="Gramene" id="ABO93709">
        <property type="protein sequence ID" value="ABO93709"/>
        <property type="gene ID" value="OSTLU_86040"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86040"/>
    <dbReference type="eggNOG" id="KOG1876">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084855_1_0_1"/>
    <dbReference type="OMA" id="EAYLGEF"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039100">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="171" mass="18901" checksum="397D62528DC222C0" modified="2007-05-15" version="1">MATSHRDYHDAVRAALEDAFALRSAPSKKMSGENRAEVEYADAPSLLMPSAEITRGCAEDGACLIERAVNSARVSVRVRQCDELEEILARAFCKSLGRRADAFEVLRRAPVEGYDVSFLVLLAHAERMEAKGLVDFVVTFMEDVDKEISEQKLSVSSRGRTVAAAYLRQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQV9</accession>
    <name>A4RQV9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
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                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="Gramene" id="ABO94091">
        <property type="protein sequence ID" value="ABO94091"/>
        <property type="gene ID" value="OSTLU_28798"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28798"/>
    <dbReference type="HOGENOM" id="CLU_1181851_0_0_1"/>
    <dbReference type="OMA" id="EEGWHRV"/>
    <dbReference type="OrthoDB" id="498316at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="25344" checksum="3F06C7967D8D6ABB" modified="2007-05-15" version="1">MSRLAPRVRVARVVSVRARRASARVRASSADAPSSAARVASLRAILGLDDRALQQLDHTVEGRAVRDDVPLSVLTERVYALSSALPRACARHAFELAVERPGLLTLDTSATRAAIERAANALGGAEQLERLCAECAPAFAHLLWRVGAREGTLADCERPLRDWAAGEVGWHRVFTQRIASEWGYLLMLGRMETSVMAGKGVVYRNVKTGESVAFRKSADFGARAAAAAAATDVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR72</accession>
    <name>A4RR72_OSTLU</name>
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        <recommendedName>
            <fullName evidence="3">CBM20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_13773</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415483.1"/>
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    <dbReference type="Gramene" id="ABO93812">
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        <property type="gene ID" value="OSTLU_13773"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13773"/>
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    <dbReference type="OMA" id="FSKMCEE"/>
    <dbReference type="OrthoDB" id="2142683at2759"/>
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    </dbReference>
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        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="CBM20"/>
    </dbReference>
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        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
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        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="3"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1194"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="666"/>
        </location>
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        <location>
            <begin position="11"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="920"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="637"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1361" mass="153231" checksum="2291756A0C94494B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR89</accession>
    <name>A4RR89_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_805</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OMA" id="DHVNIIM"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016787">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="EnsemblPlants"/>
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        <property type="project" value="EnsemblPlants"/>
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        <property type="project" value="EnsemblPlants"/>
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        <property type="project" value="EnsemblPlants"/>
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        <property type="project" value="EnsemblPlants"/>
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    </dbReference>
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        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
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        <property type="entry name" value="SKI2-like"/>
    </dbReference>
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        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH11"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HELICASE_CTER"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
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        <location>
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            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="531"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="449"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="452"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1175" mass="129380" checksum="D4DD314E4CCCE510" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRB5</accession>
    <name>A4RRB5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5A</fullName>
            <shortName evidence="4">eIF-5A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_13807</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eIF-5A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415543.1">
        <property type="nucleotide sequence ID" value="XM_001415506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRB5"/>
    <dbReference type="STRING" id="436017.A4RRB5"/>
    <dbReference type="GeneID" id="4999398"/>
    <dbReference type="Gramene" id="ABO93835">
        <property type="protein sequence ID" value="ABO93835"/>
        <property type="gene ID" value="OSTLU_13807"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13807"/>
    <dbReference type="eggNOG" id="KOG3271">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102600_0_0_1"/>
    <dbReference type="OMA" id="AKCHFTA"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04468">
        <property type="entry name" value="S1_eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000012">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000034">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0385">Hypusine</keyword>
    <keyword evidence="2 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="6">
        <location>
            <begin position="87"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18099" checksum="900F0F039ABF4BEB" modified="2007-05-15" version="1">MSDDEHDVETFESADAGASHTVPMQAGSVRKGGFMVIKGRPTKVIEVTTSKTGKHGHAKCHFTALDIFTNKKVEELVPSSHNLEVPIVNRVEYTLLDIDEDDHMSLMDDKGDTREDLKLPGGHAEAEKLAEDLRTAFDDGKEVQVTILCSMGIEQAHAIKEVNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRD9</accession>
    <name>A4RRD9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_5807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415884.1">
        <property type="nucleotide sequence ID" value="XM_001415847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRD9"/>
    <dbReference type="STRING" id="436017.A4RRD9"/>
    <dbReference type="GeneID" id="5000018"/>
    <dbReference type="Gramene" id="ABO94176">
        <property type="protein sequence ID" value="ABO94176"/>
        <property type="gene ID" value="OSTLU_5807"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5807"/>
    <dbReference type="eggNOG" id="ENOG502S7NI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1424927_0_0_1"/>
    <dbReference type="OMA" id="HPGGYGR"/>
    <dbReference type="OrthoDB" id="9675250at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008663">
        <property type="term" value="F:2',3'-cyclic-nucleotide 2'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047734">
        <property type="term" value="F:CDP-glycerol diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16509">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16509:SF8">
        <property type="entry name" value="MANGANESE-DEPENDENT ADP-RIBOSE_CDP-ALCOHOL DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="191" mass="21289" checksum="F2EBD83A99CD0C39" modified="2007-05-15" version="1" fragment="single">MFHCVGNHDCNVGKEVFLSAVNAEAAYYSASMPRGWRLIVLDTTDLNPRYVSRDAPEFDAAMRFAQDAVDEGREDVVPWGGGIGPVQFDWLRDELNDAAAKRERVIVASHNALHRDAARYQMSAWNSDEVSDLIESSGCVKICLAGHDHPGHYHYRNDVHYVTLEAMLEAAEGETSFAFLDVYEHDAVLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRE8</accession>
    <name>A4RRE8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7726 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415888.1">
        <property type="nucleotide sequence ID" value="XM_001415851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRE8"/>
    <dbReference type="GeneID" id="4999487"/>
    <dbReference type="Gramene" id="ABO94180">
        <property type="protein sequence ID" value="ABO94180"/>
        <property type="gene ID" value="OSTLU_28992"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28992"/>
    <dbReference type="HOGENOM" id="CLU_883936_0_0_1"/>
    <dbReference type="OMA" id="KWRAMEN"/>
    <dbReference type="OrthoDB" id="2592504at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056143">
        <property type="entry name" value="DUF7726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339:SF1">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24852">
        <property type="entry name" value="DUF7726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7726" evidence="1">
        <location>
            <begin position="31"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="315" mass="34633" checksum="3BF35DE56E497C3E" modified="2007-05-15" version="1">MPRNRNAVARPPGYDDLLDAYDDETRGVRATNPTTLRTKIRKFLAEFDVSVTSFQALLGVNSNSFGKFMAGHYKNKWRAMENGTYAAADYFFWREKKMKSQSVGATLRARDAGAGSSGISARSPLASTMNRHVGGLPNSAVIPARDSCGAANAKANSRGKLPDVSDVEIDGETWLTPGEVRKEISDLNRRYKFSSVELARAAECATGVQPGAPVNRFLAKGGEFGGDQMDCYDPLARFCEKMRIFEKRPKSNKRQALEIDHARRQEQLKSTPFFALLPPSATKPFLGLDGTKKHLMPSGMGFAKDSLGRLVIMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRJ2</accession>
    <name>A4RRJ2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415578.1">
        <property type="nucleotide sequence ID" value="XM_001415541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRJ2"/>
    <dbReference type="GeneID" id="4999737"/>
    <dbReference type="Gramene" id="ABO93870">
        <property type="protein sequence ID" value="ABO93870"/>
        <property type="gene ID" value="OSTLU_92174"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92174"/>
    <dbReference type="HOGENOM" id="CLU_797755_0_0_1"/>
    <dbReference type="OMA" id="HESVGRE"/>
    <dbReference type="OrthoDB" id="10597922at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="357" mass="40200" checksum="78232BD30E8FB41A" modified="2007-05-15" version="1">MRDDVEAVARATPRASTGDASASFSVSTVAKSLGDRDVVTPFDARRATMRARGHALTFENVTALMRSCAVADEESASGAQRGVRVREYLRALERATTPGRNGGADARERAREASDDRDPLRELARELLPEWRHQGESPGPKLKMRDGNGRRVDATRELEETIARMSNEAREAEAVKDEALRMKSASLAAMTTENEMLRSSLASARVASEEMERRLYETEAKEVEARETLRECMATLHEEQMAREKLREELTKVSEELHRARAAAEEALSTEMNLELRIRSLRNGDLLAALRERVIETQNELKLEVKSHDLARRRFARELMKKEAFVCRIRDKARALGMCLELLEDRDSLASDSETDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRM7</accession>
    <name>A4RRM7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_3820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415929.1">
        <property type="nucleotide sequence ID" value="XM_001415892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRM7"/>
    <dbReference type="STRING" id="436017.A4RRM7"/>
    <dbReference type="GeneID" id="4999417"/>
    <dbReference type="KEGG" id="olu:OSTLU_3820"/>
    <dbReference type="eggNOG" id="KOG0259">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_2_1"/>
    <dbReference type="OMA" id="TCYEEIK"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004838">
        <property type="term" value="F:L-tyrosine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005958">
        <property type="entry name" value="TyrNic_aminoTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01265">
        <property type="entry name" value="tyr_nico_aTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45744">
        <property type="entry name" value="TYROSINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45744:SF2">
        <property type="entry name" value="TYROSINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000517">
        <property type="entry name" value="Tyr_transaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="2"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000517-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="376" mass="41434" checksum="7DD4E4F392C9799F" modified="2007-05-15" version="1" fragment="single">LISLAQGDPTVFGHLLPPKTAMDEVAGAFSTSAHNGYTASAGSATARAAVAMRYSLPDRPPLRTEDVFMTVGCSEALSHSFAAMAVEGANILLPRPGFPLYETLCHRHGLGYKFYDLDDENGWEVKIDDVRRLRDENTVAIVVNNPSNPCGAVFSEGHLREICETCHELRLPIIADEVYEDVAFDEDRPFLSIAAFSGRVPVMVVSALSKRWLAPGWRIGWLVLHDYDHILQTAGVQLAINNLCQVSLGPPTPIQAAIPGIFKANETEWLKATLGVLRRASQRCVERCARVRGLTVPCEPQGAMYVLLKMNGDAFKDANGFFTDVTFAKRLLAEESVLVLPGTCFHAPGYLRLVITVPDDELQNAWDRIETFCERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRY5</accession>
    <name>A4RRY5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6817 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415647.1">
        <property type="nucleotide sequence ID" value="XM_001415610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRY5"/>
    <dbReference type="GeneID" id="4999963"/>
    <dbReference type="Gramene" id="ABO93939">
        <property type="protein sequence ID" value="ABO93939"/>
        <property type="gene ID" value="OSTLU_13969"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13969"/>
    <dbReference type="HOGENOM" id="CLU_901355_0_0_1"/>
    <dbReference type="OMA" id="DAWCAFR"/>
    <dbReference type="OrthoDB" id="10636990at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049202">
        <property type="entry name" value="DUF6817"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20680">
        <property type="entry name" value="DUF6817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6817" evidence="1">
        <location>
            <begin position="72"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="309" mass="33922" checksum="DCFA3C926536DC77" modified="2007-05-15" version="1">MASSERALATPSWRAVSRAVAARAMWYALDAPCAWSLGAEDARAARWDEDEATTSRMVDEDDLDDDGALLRLREARATKLTHVRGSFDAHLVDVRDWLARFGAPRSVARAGLGHAAYGSELFPCAVASFGAHRSMFRAVCGRASERLMFLYATCSQRKFYRWALTRAGAFDRETAAVNFYTGETTRALSGFEIASLALIHAADILSVQTPGRAVNTATAFAMCLVASAAATFREETRDGDADASLVDFADALENDVLDDILKAMVATSERKSKSAWRELREEAMARARHRLRRTRIDAVMVMRATGVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS32</accession>
    <name>A4RS32_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_86304</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the dispatched family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416009.1">
        <property type="nucleotide sequence ID" value="XM_001415972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS32"/>
    <dbReference type="STRING" id="436017.A4RS32"/>
    <dbReference type="GeneID" id="4999687"/>
    <dbReference type="Gramene" id="ABO94301">
        <property type="protein sequence ID" value="ABO94301"/>
        <property type="gene ID" value="OSTLU_86304"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86304"/>
    <dbReference type="eggNOG" id="KOG3664">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_393529_0_0_1"/>
    <dbReference type="OMA" id="CFMEAFR"/>
    <dbReference type="OrthoDB" id="429851at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052081">
        <property type="entry name" value="Dispatched_Hh_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003392">
        <property type="entry name" value="PTHD_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45951">
        <property type="entry name" value="PROTEIN DISPATCHED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45951:SF7">
        <property type="entry name" value="SSD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02460">
        <property type="entry name" value="Patched"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="519"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="542"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="576"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="613"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="647"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="86"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="716" mass="79868" checksum="48126E39AB6AB12C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSG3</accession>
    <name>A4RSG3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coiled-coil domain-containing protein 86</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_14346</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for proper chromosome segregation during mitosis and error-free mitotic progression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416492.1">
        <property type="nucleotide sequence ID" value="XM_001416455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSG3"/>
    <dbReference type="STRING" id="436017.A4RSG3"/>
    <dbReference type="GeneID" id="5000201"/>
    <dbReference type="Gramene" id="ABO94785">
        <property type="protein sequence ID" value="ABO94785"/>
        <property type="gene ID" value="OSTLU_14346"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14346"/>
    <dbReference type="HOGENOM" id="CLU_1483923_0_0_1"/>
    <dbReference type="OMA" id="EIDEHEC"/>
    <dbReference type="OrthoDB" id="781329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026570">
        <property type="entry name" value="CCDC86"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13557">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13557:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0164">Citrullination</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="40"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="97"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00093307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="202" mass="22618" checksum="9DF3A5379F84C4F7" modified="2007-05-15" version="1">MAGARRARRVVVDVELADARKRADGDADASANVPAQEVFRSGVDHRGITKTVKHGKRKRESDDAATNEGGEDEEMVDGELYRNYKAPKATYDSIAGRKSGRMWKQPAKRASALGAAPSTKTWDDRMREKEEKKRFQEAKSNAKAARGAKIRAERERREAKKLLKEENTRRTGVGIVSEITNPKTIAKKSAKERAKLKKLRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSI0</accession>
    <name>A4RSI0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-guanine(15) transglycosylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_35942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416242.1">
        <property type="nucleotide sequence ID" value="XM_001416205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSI0"/>
    <dbReference type="STRING" id="436017.A4RSI0"/>
    <dbReference type="GeneID" id="5000491"/>
    <dbReference type="Gramene" id="ABO94535">
        <property type="protein sequence ID" value="ABO94535"/>
        <property type="gene ID" value="OSTLU_35942"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35942"/>
    <dbReference type="eggNOG" id="KOG3909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037350_0_1_1"/>
    <dbReference type="OMA" id="AYSINIW"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="32866" checksum="94EEF2EB1C70903A" modified="2007-05-15" version="1">MNAQNRSGADALACETPYGQRSLDAREYARIWRSGAAHAAVSLADEHGGWESAKKSKTAAIRTCAWLDACAKEAKTLRLPLFGALTGGEHAEVREECSRRVAERDDDVVGYALSGFFAGEDVSTRGACVEASLKHIPSEKPRYLSGTTTVEDIVDNIDRGVDVFDASWASETAQRGRAFCFPVDEEDDEMEAEDAESRATSGSDAYSINIWSTSYKTDFTPFIRGDRCRCPACAEHTRAYVHHLLQAHEMTADVLLEAHNLYHIAAFFAAARRAIRCGRWQEFAAFHRAYAQRARET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP2</accession>
    <name>A4RSP2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PsbX, PSII-X, photosystem II polypeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">psbX</name>
        <name evidence="7" type="ORF">OSTLU_30175</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416212.1">
        <property type="nucleotide sequence ID" value="XM_001416175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP2"/>
    <dbReference type="STRING" id="436017.A4RSP2"/>
    <dbReference type="GeneID" id="5000447"/>
    <dbReference type="Gramene" id="ABO94505">
        <property type="protein sequence ID" value="ABO94505"/>
        <property type="gene ID" value="OSTLU_30175"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30175"/>
    <dbReference type="eggNOG" id="ENOG502S31P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2762380_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009518">
        <property type="entry name" value="PSII_PsbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34455">
        <property type="entry name" value="OS07G0673550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34455:SF1">
        <property type="entry name" value="OS07G0673550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06596">
        <property type="entry name" value="PsbX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="70" mass="7030" checksum="85FF4291066BB9FA" modified="2007-05-15" version="1">MRRVEKVKSKASAAMSAAVITSMTSPLLAEASVTPSLKNTLLSVVAGGVVLGAIAAAVIGVSSFDKVSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSQ7</accession>
    <name>A4RSQ7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Replication factor C subunit 5 (36kDa), probable</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rfc5</name>
        <name evidence="9" type="ORF">OSTLU_119614</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex with RFC1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416450.1">
        <property type="nucleotide sequence ID" value="XM_001416413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSQ7"/>
    <dbReference type="STRING" id="436017.A4RSQ7"/>
    <dbReference type="GeneID" id="5000408"/>
    <dbReference type="Gramene" id="ABO94743">
        <property type="protein sequence ID" value="ABO94743"/>
        <property type="gene ID" value="OSTLU_119614"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119614"/>
    <dbReference type="eggNOG" id="KOG0990">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_2_1_1"/>
    <dbReference type="OMA" id="ICNHISQ"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031348">
        <property type="term" value="P:negative regulation of defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000129">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF9">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="45"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="332" mass="37184" checksum="7C3CCA907D011B9E" modified="2007-05-15" version="1">MVCVDDPSVNRALPWTEKYRPVGLSEVVAHKAIVDVINKFADGGQLPHLLFHGPPGTGKTSTILALAKELYGLNFSNMVLELNASDARGINVVRDEIQSFASTMRPFSTTFKLVIMDECDSMTKDAQFALRRIMEKYTQHTRFCLICNYASKVIPALQSRCTKFRFSPIASGDMLQRLRHIVNSENFSISDNSLATIQKLGEGDMRKTVNILQSVSLSASVVTDDAIHLITGHVGQLQVDELLRFLLNEPLQGTFEHFNRLKCTQNFALVDIVKPLSESLLTLHMAAGTRARLLRGLSDIEYSLSFACSEKNQTLYLISLFHQARFEMTRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSW3</accession>
    <name>A4RSW3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">separase</fullName>
            <ecNumber evidence="2">3.4.22.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Cut1</name>
        <name evidence="7" type="ORF">OSTLU_119551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>All bonds known to be hydrolyzed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by a hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage.</text>
            <dbReference type="EC" id="3.4.22.49"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.22.49" evidence="2"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416421.1">
        <property type="nucleotide sequence ID" value="XM_001416384.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RSW3"/>
    <dbReference type="GeneID" id="5000366"/>
    <dbReference type="Gramene" id="ABO94714">
        <property type="protein sequence ID" value="ABO94714"/>
        <property type="gene ID" value="OSTLU_119551"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119551"/>
    <dbReference type="eggNOG" id="KOG1849">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_239435_0_0_1"/>
    <dbReference type="OMA" id="CWALLKD"/>
    <dbReference type="OrthoDB" id="10255632at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051307">
        <property type="term" value="P:meiotic chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005314">
        <property type="entry name" value="Peptidase_C50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030397">
        <property type="entry name" value="SEPARIN_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792">
        <property type="entry name" value="EXTRA SPINDLE POLES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792:SF0">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03568">
        <property type="entry name" value="Separin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51700">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C50" evidence="6">
        <location>
            <begin position="1562"/>
            <end position="1656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1750" mass="196035" checksum="9170EF17F444A981" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSW7</accession>
    <name>A4RSW7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VatL</name>
        <name evidence="11" type="ORF">OSTLU_119546</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416171.1">
        <property type="nucleotide sequence ID" value="XM_001416134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSW7"/>
    <dbReference type="STRING" id="436017.A4RSW7"/>
    <dbReference type="GeneID" id="5000245"/>
    <dbReference type="Gramene" id="ABO94464">
        <property type="protein sequence ID" value="ABO94464"/>
        <property type="gene ID" value="OSTLU_119546"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119546"/>
    <dbReference type="eggNOG" id="KOG0232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085752_1_0_1"/>
    <dbReference type="OMA" id="HLCAGVC"/>
    <dbReference type="OrthoDB" id="645039at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="10">
        <location>
            <begin position="13"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="10">
        <location>
            <begin position="91"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="154" mass="15599" checksum="D2A8EF6CD7B51EAE" modified="2007-05-15" version="1">MLIARGAFFGFAGATFCLVLSCLGAAYGTSQAGIGLCRGSAKRPSVTIKAIIPVAMAGVRGIYGLVLSIIILASATSAGESYSEFSGLLHLCAGVCCGMAQFASGITVGVIGESSTQAIVTRPRLFAPAILILIFSEALALYGLISGMILVQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT11</accession>
    <name>A4RT11_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Ogd</name>
        <name evidence="10" type="ORF">OSTLU_119509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[ribosomal protein uS12]-L-proline + 2-oxoglutarate + O2 = [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54156"/>
            <dbReference type="Rhea" id="RHEA-COMP:13816"/>
            <dbReference type="Rhea" id="RHEA-COMP:13818"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:85428"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TPA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416153.1">
        <property type="nucleotide sequence ID" value="XM_001416116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT11"/>
    <dbReference type="STRING" id="436017.A4RT11"/>
    <dbReference type="GeneID" id="5000410"/>
    <dbReference type="Gramene" id="ABO94446">
        <property type="protein sequence ID" value="ABO94446"/>
        <property type="gene ID" value="OSTLU_119509"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119509"/>
    <dbReference type="eggNOG" id="KOG3844">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017005_0_0_1"/>
    <dbReference type="OMA" id="GWYHIPQ"/>
    <dbReference type="OrthoDB" id="430522at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.20">
        <property type="entry name" value="Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019601">
        <property type="entry name" value="Oxoglutarate/Fe-dep_Oase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043044">
        <property type="entry name" value="TPA1/Ofd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039558">
        <property type="entry name" value="TPA1/OFD1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051842">
        <property type="entry name" value="uS12_prolyl_hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117:SF0">
        <property type="entry name" value="PROLYL 3-HYDROXYLASE OGFOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13661">
        <property type="entry name" value="2OG-FeII_Oxy_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10637">
        <property type="entry name" value="Ofd1_CTDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="114"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="519" mass="58622" checksum="D7C4A245617A2769" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTA1</accession>
    <name>A4RTA1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutamate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_36228</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416110.1">
        <property type="nucleotide sequence ID" value="XM_001416073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTA1"/>
    <dbReference type="STRING" id="436017.A4RTA1"/>
    <dbReference type="GeneID" id="5000163"/>
    <dbReference type="Gramene" id="ABO94402">
        <property type="protein sequence ID" value="ABO94402"/>
        <property type="gene ID" value="OSTLU_36228"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36228"/>
    <dbReference type="eggNOG" id="KOG0629">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011856_0_0_1"/>
    <dbReference type="OMA" id="RHATYHA"/>
    <dbReference type="OrthoDB" id="639767at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677:SF8">
        <property type="entry name" value="CYSTEINE SULFINIC ACID DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="49295" checksum="EA6D4535DDABD725" modified="2007-05-15" version="1">MGVPLNFRSGESPISINNLTTAMNAVLDNSVRSSHPMFMNQLYAGVDPIALAGEWASSALNSNVHTFEVAPILTEIERSMLAKIASLWLGENADGSAPDHDGLFVPGGSIANLYSMILARERACPEAKKTGMPQGYVAFCSEQSHYSYKKCAHMIGLGMDNMIKVDCGKNGAMLPEALEAAIAAAKAAGKTPFYCGATAGSTVLGAYDPFAALADVCAKDNVWLHVDGAWGGAALVSKQHKHLMNGVERADSFCWNPHKLLGIPLQCSIVLSRHAGEFMAANSYKADYLFQPDKNNTEADLGDRTIQCGRKSDALKLWLAWKYRGDEGWEKLVDHAFSLAKFVEAEVVQDTTGAWALATPAQCANVGFWYVPPRLRPFNKDTATPEQFAEIAKVAPKLKDRMQRAGDAMIGFQPVPALNLPNFFRLVLPNPRHNSETKLRELMKRMDAMGADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTB5</accession>
    <name>A4RTB5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NAD(+) kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_35817</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416344.1">
        <property type="nucleotide sequence ID" value="XM_001416307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTB5"/>
    <dbReference type="STRING" id="436017.A4RTB5"/>
    <dbReference type="GeneID" id="5000071"/>
    <dbReference type="Gramene" id="ABO94637">
        <property type="protein sequence ID" value="ABO94637"/>
        <property type="gene ID" value="OSTLU_35817"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35817"/>
    <dbReference type="eggNOG" id="KOG2178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008831_10_2_1"/>
    <dbReference type="OMA" id="QYLCNID"/>
    <dbReference type="OrthoDB" id="24581at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000009">
        <property type="entry name" value="Poly(P)/ATP NAD kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF0">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="34052" checksum="0DA8A4ADC536A61A" modified="2007-05-15" version="1" fragment="single">KFSWLEAPRNALVVKKIHDAAAAEMMIRATRVLKSKGVTAWLERAVWDEFAELQGDCQTWDAGDASFHLDEIIDFIVVLGGDGTILWASKYFPKAMPPVVPFAMGSLGFLTSHRVDDMEKKLAVVMQGDFTISMRSRLVAKVVSAEGVSSQWRYVLNEVLIDRGPKPVMVELDIAVDGYHVTKVAADGVILSSPTGSTAYSLAAGGSMVHPGVPALCVTPICPHSLSFRPIVLPDSVVVTITCPRDARNTAWAAFDGKFQTELARGDAVVVRVAGFPVPSVCNASENNDWFAAVKQGLLWNARGADQKPIERKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTW4</accession>
    <name>A4RTW4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416566.1">
        <property type="nucleotide sequence ID" value="XM_001416529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTW4"/>
    <dbReference type="GeneID" id="5000591"/>
    <dbReference type="Gramene" id="ABO94859">
        <property type="protein sequence ID" value="ABO94859"/>
        <property type="gene ID" value="OSTLU_92376"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92376"/>
    <dbReference type="eggNOG" id="ENOG502SC25">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_931867_0_0_1"/>
    <dbReference type="OMA" id="CARIEHC"/>
    <dbReference type="OrthoDB" id="46661at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="299" mass="31671" checksum="8486C996E08FF662" modified="2007-05-15" version="1">MVRATTRDERARVYIEHTDAYGVVFYANYFAFASNAAEALGRVAAGGGGGGGGGGANAGGFDFGRAFRCARIEHCKYARAATLGDAIAVRSEVVRADERSATLRQEIVSANDDADETVFLSAEITYAGAGAETDDSVGVGDTAGDETFAAPWEMEDGRCASTAVRMYRGERSAAQRSHVDILRFFERARTDAIGGSDALSALQDDGVVVVVSRLQAYFPRGDGSQSKSSSSVIPVYDVKSTVELKRRGIQVVFHQAMFADDGACVGYGDVTCTCLDAKTMRPMPCPPALVDTFAPFCIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU07</accession>
    <name>A4RU07_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416588.1">
        <property type="nucleotide sequence ID" value="XM_001416551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU07"/>
    <dbReference type="STRING" id="436017.A4RU07"/>
    <dbReference type="GeneID" id="5001084"/>
    <dbReference type="Gramene" id="ABO94881">
        <property type="protein sequence ID" value="ABO94881"/>
        <property type="gene ID" value="OSTLU_92390"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92390"/>
    <dbReference type="eggNOG" id="ENOG502QRPA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1084121_0_0_1"/>
    <dbReference type="OMA" id="DEMYTID"/>
    <dbReference type="OrthoDB" id="498569at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="23"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="257" mass="27677" checksum="E45AC71D532954D8" modified="2007-05-15" version="1" fragment="single">VRPGIRPRRYRYGRKLLQQDKKCKTMLDVVESLPQLSSLKEAIKDLPKIRDALNNSTAQDTFFAPSNEAIASLTLWGGFDDFKRGLEGMFSSDEIKALVVAYHAIPDQKLNWGQLRAKAAKGEFLPTALSKIFPDSSAALEVSWWKGDIFLKGVGSEAKISAADIPACGSIVHVIDGVLLPLDGDGELSDEQKARIEAARIALGGKDEEPGDAPAPAPDAAPAPAPAEVFPDDIEELDVDYPMEDQYGEAPAPAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU61</accession>
    <name>A4RU61_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA topoisomerase 2</fullName>
            <ecNumber evidence="11">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_30508</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
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    <comment type="catalytic activity">
        <reaction evidence="1 16 11">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="11"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU61"/>
    <dbReference type="STRING" id="436017.A4RU61"/>
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    <dbReference type="Gramene" id="ABO94910">
        <property type="protein sequence ID" value="ABO94910"/>
        <property type="gene ID" value="OSTLU_30508"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30508"/>
    <dbReference type="eggNOG" id="KOG0355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006146_4_1_1"/>
    <dbReference type="OMA" id="QLWSTTM"/>
    <dbReference type="OrthoDB" id="276498at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16928">
        <property type="entry name" value="HATPase_GyrB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00822">
        <property type="entry name" value="TopoII_Trans_DNA_gyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA gyrase subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA gyrase subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000565">
        <property type="entry name" value="Topo_IIA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004189">
        <property type="entry name" value="PRK05644.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45866:SF1">
        <property type="entry name" value="DNA GYRASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45866">
        <property type="entry name" value="DNA GYRASE/TOPOISOMERASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01159">
        <property type="entry name" value="DNAGYRASEB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="13">
        <location>
            <begin position="444"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="662" mass="72512" checksum="812971AE4732B2C1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUC8</accession>
    <name>A4RUC8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RWD domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30576</name>
    </gene>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_30576"/>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25976" checksum="B12D44BCB082C740" modified="2007-05-15" version="1">MRVRIKDEAFWCDASLRTPDDYPSSSALDVHAVVSDALNREHEAAIVARAREVARASVGEESAYAVVAELEQSFKEVLAEARAARESARTTTTVEEDYHAVVRIDHMNDSVGYVKLLKKWCEGEGLGARALHKPATASGRIEGVFVALSGPNDGIKSFLQRLRTELVDVDSKGVRCRERKATTLCHRKRSTVKPGERAVESFHGFELIPYDTEGQLEDALAKLNLLHVGDGASRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUW9</accession>
    <name>A4RUW9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_34219</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417034.1">
        <property type="nucleotide sequence ID" value="XM_001416997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUW9"/>
    <dbReference type="STRING" id="436017.A4RUW9"/>
    <dbReference type="GeneID" id="5001131"/>
    <dbReference type="Gramene" id="ABO95327">
        <property type="protein sequence ID" value="ABO95327"/>
        <property type="gene ID" value="OSTLU_34219"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34219"/>
    <dbReference type="eggNOG" id="KOG0296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_9_1"/>
    <dbReference type="OMA" id="GPDEVMW"/>
    <dbReference type="OrthoDB" id="10261640at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000074">
        <property type="entry name" value="Angio-associated migratory cell protein-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="72"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="114"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="156"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="244"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="285"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="327"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="364" mass="38202" checksum="EC9F066E0993A1B0" modified="2007-05-15" version="1">MDGDGTTTEDRDAAASTTIAPPRDDAECVAATHDAPVYAVAWSNDGAEATVVSGGGDDKGYLRRGAGEARELGGHGESVSCAAFSADGGLLATGGLDGKVCIYDGKTGAVERALEGPGGGIEWVAWHPRGRVTLAGSEDFTAWMWNGDDGALMQVFSGHSERVSCGGFTPDGKQVVTGSYDGSLRVWQPRTGACEHAFRGHPFHDGPLTCVAFHPSTLGLTITGSEDNTARLVSTTTGKVLAPLVAHTETIEAVGFSDIMPVCATGSLDKQIIIWDTNSCQARGTLSHGGAVSQLRWIPNTMCLYSTSVDGIVRLWDARTSTCQREAHGHTKGILDFAMSPDYARVITASDDCTARIFNFSNPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV13</accession>
    <name>A4RV13_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_14772</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416763.1">
        <property type="nucleotide sequence ID" value="XM_001416726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV13"/>
    <dbReference type="STRING" id="436017.A4RV13"/>
    <dbReference type="GeneID" id="5000614"/>
    <dbReference type="Gramene" id="ABO95056">
        <property type="protein sequence ID" value="ABO95056"/>
        <property type="gene ID" value="OSTLU_14772"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14772"/>
    <dbReference type="eggNOG" id="KOG2907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093932_1_1_1"/>
    <dbReference type="OMA" id="PKCKHKG"/>
    <dbReference type="OrthoDB" id="10056816at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10507">
        <property type="entry name" value="Zn-ribbon_RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034004">
        <property type="entry name" value="Zn_ribbon_RPA12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF14">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="11">
        <location>
            <begin position="82"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="125" mass="13985" checksum="7AEFCFA1F12C816C" modified="2007-05-15" version="1">MASARGFCERCGARLRLTTRAPDVRCDACGRARALEDAFGDGERELTAGAREFKFHHGVEARHPNGTRVGATEEVTRERATVDEKCPKCKHKGLNFYTMQLRSADEGQTVFYECPKCSHTFSQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVD0</accession>
    <name>A4RVD0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_86880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO95410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001417080.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="5001170"/>
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        <property type="protein sequence ID" value="ABO95410"/>
        <property type="gene ID" value="OSTLU_86880"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86880"/>
    <dbReference type="eggNOG" id="ENOG502QRC7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rieske-like_NirD"/>
    </dbReference>
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        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43456">
        <property type="entry name" value="RIESKE (2FE-2S) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43456:SF2">
        <property type="entry name" value="RIESKE (2FE-2S) DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF13806">
        <property type="entry name" value="Rieske_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="8">
        <location>
            <begin position="12"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="24957" checksum="F695E2DA0956F12D" modified="2007-05-15" version="1" fragment="single">VSASADGAESMTRVCALEELPRGDRKLVRALGKSILMFWYRDTVFAIESRSPAEGAYSEGFEKARLTQDACIECPTTKSKFDLKTGEIKEWYPENPVLKALTPQDTCRPMEVFPVEVRDDGIYLDAKNGSLGPGFVAPIGLGGSNTSLENNNVFAVETPMYVEGEGIGGSMASGGDSSGKMDASQLGGAIAVAGVVAVAGTGACLYFENFYALAALWIAGFAAAAGVALKTTGALDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVI6</accession>
    <name>A4RVI6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_10507</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417146.1">
        <property type="nucleotide sequence ID" value="XM_001417109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVI6"/>
    <dbReference type="STRING" id="436017.A4RVI6"/>
    <dbReference type="GeneID" id="5001148"/>
    <dbReference type="Gramene" id="ABO95439">
        <property type="protein sequence ID" value="ABO95439"/>
        <property type="gene ID" value="OSTLU_10507"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10507"/>
    <dbReference type="eggNOG" id="KOG1124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243496_0_0_1"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006626">
        <property type="term" value="P:protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051982">
        <property type="entry name" value="CiliaryAsmbly_MitoImport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45984">
        <property type="entry name" value="RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45984:SF1">
        <property type="entry name" value="SPAG1 AXONEMAL DYNEIN ASSEMBLY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="105" mass="11732" checksum="3DF058AF934260D6" modified="2007-05-15" version="1" fragment="single">SPEELKARGNAFLREGDTVRAEETYTLAIDKGDATGATLVALYNNRAEARRRAGAYDAVVEDCTKVLELDPRNLKATLRRGGTYEILEKYSRACEDYEFALEIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVQ7</accession>
    <name>A4RVQ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nop domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_94220</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417188.1">
        <property type="nucleotide sequence ID" value="XM_001417151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVQ7"/>
    <dbReference type="STRING" id="436017.A4RVQ7"/>
    <dbReference type="GeneID" id="5001447"/>
    <dbReference type="Gramene" id="ABO95481">
        <property type="protein sequence ID" value="ABO95481"/>
        <property type="gene ID" value="OSTLU_94220"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94220"/>
    <dbReference type="eggNOG" id="KOG2574">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026337_2_1_1"/>
    <dbReference type="OMA" id="SFVHHAI"/>
    <dbReference type="OrthoDB" id="4771285at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000002">
        <property type="entry name" value="U4/U6 small nuclear ribonucleoprotein Prp31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000003">
        <property type="entry name" value="U4/U6 small nuclear ribonucleoprotein PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027105">
        <property type="entry name" value="Prp31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019175">
        <property type="entry name" value="Prp31_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09785">
        <property type="entry name" value="Prp31_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Nop" evidence="10">
        <location>
            <begin position="144"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="393" mass="41919" checksum="55127360329815A5" modified="2007-05-15" version="1">MDGATTTASGKRAGAIDEGAEALVVECNALTVEVDNEVAVVHQYIKDRYKSKFPELESLVLHPIDYARVVKAIGNEMDMMGVELDGVLPSATIMVVSVTGSTTSGQPLSESDLEKTLRACDRALELDEAKKKMFNYVATRMADTAPNLSAVLGSDIAAQLIGIAGGLHALSKMPACNVQVLGSKKKATAGMSSASAVRAGDLHAGFIYDCDIIQKKTPPAWRSKAARLIGAKCSLMARVDAYGESPDGATGKKFAEEIMKKIEKWQEPPPARTAKPLPAPGVEQKKRRGGRRARALKERYGLTDMRKAANRVNFNEVEEEAAKLIKTDNKGGKSTFASTAGTSGMASSLAFTPVQGIELVNPNRTASDGPVSGTDSVFSERRGFSNVARQLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVW1</accession>
    <name>A4RVW1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_37444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417218.1">
        <property type="nucleotide sequence ID" value="XM_001417181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVW1"/>
    <dbReference type="STRING" id="436017.A4RVW1"/>
    <dbReference type="GeneID" id="5001172"/>
    <dbReference type="Gramene" id="ABO95511">
        <property type="protein sequence ID" value="ABO95511"/>
        <property type="gene ID" value="OSTLU_37444"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37444"/>
    <dbReference type="eggNOG" id="KOG2338">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016428_0_0_1"/>
    <dbReference type="OMA" id="HQENIEY"/>
    <dbReference type="OrthoDB" id="497642at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF36">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="70"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="42595" checksum="FD574DB3B42CBDFB" modified="2007-05-15" version="1">MPDGVTPAERHARAGVRARRWSSRKRKRAAAAAVEFRLVSYNLLARQYTTQLGRALYRVGPHRLEWSSRAKTLRCELEMLSGDVVCAQEYEEKAWRGNEALLGDEYARAALCERSGEARGEKRAEKREGCAIFIRRGAFTCETTEKLKFDDYGLGDNAACVVTLRHRARDGFRLVVANAHLLFNPKRGDAKVGQVRVLLATVARIRQDIVDRGLMAHCVICGDFNFSPNSALYHFFSNGRLDLSEVNRRELSGTLVDVLDDRNVGDDQVTQSASQSATQKRGTDVEQVKNLMRLTPGGFTVHHAFEAELSSAYVAVAGGEPAFTTCHNKFCGTNDYIWYTSNLEPTRVLQSPSLDDVLRYGKLPSVRYASDHVSIGADFRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW24</accession>
    <name>A4RW24_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417511.1">
        <property type="nucleotide sequence ID" value="XM_001417474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW24"/>
    <dbReference type="GeneID" id="5001277"/>
    <dbReference type="Gramene" id="ABO95804">
        <property type="protein sequence ID" value="ABO95804"/>
        <property type="gene ID" value="OSTLU_92611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92611"/>
    <dbReference type="eggNOG" id="ENOG502S9Z2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1350857_0_0_1"/>
    <dbReference type="OMA" id="THEIVNC"/>
    <dbReference type="OrthoDB" id="498304at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="203" mass="22094" checksum="195A5BF217D01A4C" modified="2007-05-15" version="1">MRRALARLARDVASRRSSDARAVAPRRATRGNHDGDARGCCDAAATSPPRFTSTHEIVNCAHAHGARSTYAVGMSAYAFELIGDATRVEPTRASGETVAKGETLARVHWSGFTRTAGDELYHSRWANASGTREIAAPFDVKVVRYNMEALRDPYMNVRGPETWLAEVEAESGSTATLMDEEDYDALVEREEMAAADKANAAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW75</accession>
    <name>A4RW75_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle 14 kDa protein</fullName>
            <shortName evidence="7">SRP14</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_9161</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SRP14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417533.1">
        <property type="nucleotide sequence ID" value="XM_001417496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW75"/>
    <dbReference type="STRING" id="436017.A4RW75"/>
    <dbReference type="GeneID" id="5001342"/>
    <dbReference type="Gramene" id="ABO95826">
        <property type="protein sequence ID" value="ABO95826"/>
        <property type="gene ID" value="OSTLU_9161"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9161"/>
    <dbReference type="eggNOG" id="KOG1761">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094309_2_0_1"/>
    <dbReference type="OMA" id="RFNGHNK"/>
    <dbReference type="OrthoDB" id="19209at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003210">
        <property type="entry name" value="Signal_recog_particle_SRP14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12013">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02290">
        <property type="entry name" value="SRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="119" mass="13286" checksum="40C7C787F0685E03" modified="2007-05-15" version="1" fragment="single">MVLLENDAFLTELTKLYERTRAKGSVSCVMKITKPTNKPRPKGTKRPDPTLEEIRAPGSEYGVLVRASDGKRKVSTFVKPEKASKFSKSYQTIQLAYLDGLSAETKKKKKKPTAKAKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWB2</accession>
    <name>A4RWB2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Telomerase reverse transcriptase</fullName>
            <ecNumber evidence="2 13">2.7.7.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Telomerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_15108</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.49"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Chromosome</location>
            <location evidence="13">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the reverse transcriptase family. Telomerase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="2 13"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417297.1">
        <property type="nucleotide sequence ID" value="XM_001417260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWB2"/>
    <dbReference type="STRING" id="436017.A4RWB2"/>
    <dbReference type="GeneID" id="5001513"/>
    <dbReference type="Gramene" id="ABO95590">
        <property type="protein sequence ID" value="ABO95590"/>
        <property type="gene ID" value="OSTLU_15108"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15108"/>
    <dbReference type="eggNOG" id="KOG1005">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_302368_0_0_1"/>
    <dbReference type="OMA" id="FMFRSSF"/>
    <dbReference type="OrthoDB" id="289721at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000333">
        <property type="term" value="C:telomerase catalytic core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003720">
        <property type="term" value="F:telomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01648">
        <property type="entry name" value="TERT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021891">
        <property type="entry name" value="Telomerase_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003545">
        <property type="entry name" value="Telomerase_RT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049139">
        <property type="entry name" value="TERT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066:SF0">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12009">
        <property type="entry name" value="Telomerase_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21399">
        <property type="entry name" value="TERT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01365">
        <property type="entry name" value="TELOMERASERT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00975">
        <property type="entry name" value="Telomerase_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="9 13" id="KW-0779">Telomere</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="15">
        <location>
            <begin position="441"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO95590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="987" mass="111488" checksum="78A103B6EEFAD1E5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWB4</accession>
    <name>A4RWB4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_15110</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417552.1">
        <property type="nucleotide sequence ID" value="XM_001417515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWB4"/>
    <dbReference type="GeneID" id="5001514"/>
    <dbReference type="Gramene" id="ABO95845">
        <property type="protein sequence ID" value="ABO95845"/>
        <property type="gene ID" value="OSTLU_15110"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15110"/>
    <dbReference type="eggNOG" id="KOG4232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016265_2_0_1"/>
    <dbReference type="OMA" id="YAWWNDK"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF30">
        <property type="entry name" value="DELTA 8-(E)-SPHINGOLIPID DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="14">
        <location>
            <begin position="59"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO95845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="498" mass="55924" checksum="B7A0B851EB564248" modified="2007-05-15" version="1">MPRDGVDLSRRARARRRGDASATRATAREGEGARRANRGDASAARDVGTGVGGETRRGEATYARADVRSHDVGSDCWLVVGDGVYDATSWVEKHPGGSTILEQYAGRDATDAFMAYHGGERRALARLETLRIGRLVDESAAPPTHLKAFRRMRDAMEGSEKLLKSDLTDYAFIIARLVVLFGGVLACVLSSGAGFKTHMFGAVLLGLFWQQSMFIGHDAGHTSITYDRKKDAMIGWCVGNLFNGVGIAWWMATHNVHHCACNSLECDPDIQHMPVFAVSNKYFGSVYSLYHRRRMTYDRLARTLVRFQHYTFYPIMAVARINLYLQTLIFLIKAKRVRSRAMEFLTLGVFATWLTTLIAQLPVGHKVPFFFLSHAVAGVIHVQICLSHFSRDVFEGRPENDEWVNMQLAGTLDIDCPRWLDWFHGGLQFQTEHHLCPRVPRHKLRAFREDVVKPYAKANGLGLHSVSFWAANAEVFRTLKLAAKQSRWAPHFSSAMHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWD2</accession>
    <name>A4RWD2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417308.1">
        <property type="nucleotide sequence ID" value="XM_001417271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWD2"/>
    <dbReference type="GeneID" id="5001489"/>
    <dbReference type="Gramene" id="ABO95601">
        <property type="protein sequence ID" value="ABO95601"/>
        <property type="gene ID" value="OSTLU_31298"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31298"/>
    <dbReference type="HOGENOM" id="CLU_1463593_0_0_1"/>
    <dbReference type="OMA" id="TIWSYRD"/>
    <dbReference type="OrthoDB" id="10412219at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20511" checksum="ABCEE8749491D804" modified="2007-05-15" version="1">MATDGARGGGATATDAKKNDGRTIWSYRDECQTWRNYDASKGLRYTRESIDAMTRAHESFGELTKDLDMDIDDPGERALNILRRERADPTRPPDEPTPLRLKPFDASPGDETCVVKYTFRNELTTIGEVVEELAEMLGLMPCAVSLVHAGRELGPLEHTLTDCGVCANYVVYWRVKNGIAVVTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWP4</accession>
    <name>A4RWP4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_37027</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417365.1">
        <property type="nucleotide sequence ID" value="XM_001417328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWP4"/>
    <dbReference type="STRING" id="436017.A4RWP4"/>
    <dbReference type="GeneID" id="5001274"/>
    <dbReference type="Gramene" id="ABO95658">
        <property type="protein sequence ID" value="ABO95658"/>
        <property type="gene ID" value="OSTLU_37027"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37027"/>
    <dbReference type="eggNOG" id="KOG1715">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_3_0_1"/>
    <dbReference type="OMA" id="ATIKAHF"/>
    <dbReference type="OrthoDB" id="250175at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_bL12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="5">
        <location>
            <begin position="25"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="82"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="15486" checksum="C209F156F46E3453" modified="2007-05-15" version="1">MSRAQPTSVRPTAAKRTSVVLASAKTDAIIEEMKTLTLLEASELVAQIEEVFGVDASAPAGGMMMAAGPAAGGEAAEEKTEFDLVIDNVDADKRIAIIKVVRGLTDLGLKEAKDAVTNVPFTILAGKTKGEVEEAKKALEEGGAKCSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWT1</accession>
    <name>A4RWT1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_87146</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417385.1">
        <property type="nucleotide sequence ID" value="XM_001417348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWT1"/>
    <dbReference type="STRING" id="436017.A4RWT1"/>
    <dbReference type="GeneID" id="5001585"/>
    <dbReference type="Gramene" id="ABO95678">
        <property type="protein sequence ID" value="ABO95678"/>
        <property type="gene ID" value="OSTLU_87146"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87146"/>
    <dbReference type="eggNOG" id="KOG0335">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="DANMHEW"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17967">
        <property type="entry name" value="DEADc_DDX3_DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000397">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044763">
        <property type="entry name" value="Ded1/Dbp1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="81"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="292"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="436"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="439"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="480" mass="52024" checksum="FB15B7B1A47BD595" modified="2007-05-15" version="1">MEEEEAAAARNDPDSEATKMFTGENTGLDFDLYDDIPVETSGRDVPEPITSFVDLDLGAAVNTNIKRCKFKNPTPVQKYAIPASLAGRDLMACAQTGSGKTAAFCFPIIAGILKRGLQGGHMNRKTYPLALVLSPTRELASQIHEESRKFAYQTGVASCVIYGGAPAVEQFRAMERGCDILVATPGRLIDLIDRAKISLSRVQYLALDEADRMLDMGFEPQIRQIVDERDMPRCGERQTMLFSATFPREIQRMASDFLDDYVFLTVGRVGSSHALITQSVERVTSYHEKSNMLLDLVEAVPGLTLVFVETKRGADQLEDFLYQNGKPATSIHGDRTQQEREAALKSFRAGKTPILVATDVAARGLDIPHVTHVINFDLPSDIDDYTHRIGRTGRAGKKGRATALFLESKDGQMARPLTELMSEANQEVPTWLTQISGHSFGGGGRRRGGGGGNRFGGRDYRGGGGGGGGGGGGGGGWGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWY2</accession>
    <name>A4RWY2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417657.1">
        <property type="nucleotide sequence ID" value="XM_001417620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWY2"/>
    <dbReference type="STRING" id="436017.A4RWY2"/>
    <dbReference type="GeneID" id="5002096"/>
    <dbReference type="Gramene" id="ABO95950">
        <property type="protein sequence ID" value="ABO95950"/>
        <property type="gene ID" value="OSTLU_31498"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31498"/>
    <dbReference type="eggNOG" id="KOG1576">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_5_0_1"/>
    <dbReference type="OMA" id="DYDNMFD"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19152">
        <property type="entry name" value="AKR_AKR15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686:SF1">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="356" mass="38112" checksum="F5CF685C8C18FEB1" modified="2007-05-15" version="1">MASGRAGTPAATLGTLRAHDAKRALAVDRLILGASPLAGIYRGVDASEAAATVRAALDVGFTRFDTAPHYGLGLSETRLGEALRTHAKKAVKVYTKVGRVMKPMDEVTESERESVVEWGNVPGNDGCIFPDAPRDVLPVLDYSANGFVRSHADSLNRLGIDRIEGLRIHDAETPERFEAATTGGGVRALTALRDAGTISEVSLGMNDASYVLRMIRENPPGTFDSVMMAGSWNLLDQDGLEVLLECQARNIKVHNAGVFASGVLVGGSHYKYGPAPDEIKRRTEKWNVLARAYDIPLPAIALAFALTPEVVDSCAVGVKSPDEVAQSVAWLADAARVPRQLWLDAFSQGLLAWIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX19</accession>
    <name>A4RX19_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_6256</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SFH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417676.1">
        <property type="nucleotide sequence ID" value="XM_001417639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX19"/>
    <dbReference type="GeneID" id="5001968"/>
    <dbReference type="Gramene" id="ABO95969">
        <property type="protein sequence ID" value="ABO95969"/>
        <property type="gene ID" value="OSTLU_6256"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6256"/>
    <dbReference type="eggNOG" id="KOG1471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014001_0_1_1"/>
    <dbReference type="OMA" id="FSTMFKM"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="4">
        <location>
            <begin position="45"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="195" mass="22079" checksum="C5C169F3889682DA" modified="2007-05-15" version="1" fragment="single">EERALLKFVRARKSAEKSYEMLRNTLAWRARERVDACLSEPIDDDKLKHVERIPAYYAGFGKTGHPIYVEHTAVIPWPTILEHMTADEFLKSQVQTLEWQASVVYPEASRRAGEPITQVINVWDLKGLTMSGFTSEIRAFVKKASAVAQDNYPEGLYAAYIVNAPKIFSFVWAVVKQFLDAKTVAKVHIYGSGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXV7</accession>
    <name>A4RXV7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417820.1">
        <property type="nucleotide sequence ID" value="XM_001417783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXV7"/>
    <dbReference type="GeneID" id="5001773"/>
    <dbReference type="Gramene" id="ABO96113">
        <property type="protein sequence ID" value="ABO96113"/>
        <property type="gene ID" value="OSTLU_31833"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31833"/>
    <dbReference type="HOGENOM" id="CLU_009007_0_0_1"/>
    <dbReference type="OMA" id="ANVPSCR"/>
    <dbReference type="OrthoDB" id="10386310at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672961" description="IPT/TIG domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="140"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="937"/>
            <end position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1133" mass="116843" checksum="F826C171491461F9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXW5</accession>
    <name>A4RXW5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 13">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_87349</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Endoplasmic reticulum membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 13"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418068.1">
        <property type="nucleotide sequence ID" value="XM_001418031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXW5"/>
    <dbReference type="STRING" id="436017.A4RXW5"/>
    <dbReference type="GeneID" id="5001952"/>
    <dbReference type="Gramene" id="ABO96361">
        <property type="protein sequence ID" value="ABO96361"/>
        <property type="gene ID" value="OSTLU_87349"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87349"/>
    <dbReference type="eggNOG" id="KOG3187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034302_2_2_1"/>
    <dbReference type="OMA" id="LGLTMEW"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF35">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="215" mass="23769" checksum="C5CD9A70955072A7" modified="2007-05-15" version="1">MGALARRYLVLYNVAQACGWLTVLAKASRASLDDATGAYDACRSTLMVFQLASFAEIAHAVAGLTPTPAAAALAQWSGRTHCLKCALDAVKTSHASVAATALVFAWALTEVVRYPSYVGGLIGRSPKWLTWSRYTVFVPLYPLGAAAEMKLMYDARAHARKTKMYAVTMPNAYNFAFDYVTFLNALLVAYPFLFYTLYRYMFAQRRKKLGKAKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY41</accession>
    <name>A4RY41_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_87388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417866.1">
        <property type="nucleotide sequence ID" value="XM_001417829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY41"/>
    <dbReference type="STRING" id="436017.A4RY41"/>
    <dbReference type="GeneID" id="5002024"/>
    <dbReference type="Gramene" id="ABO96159">
        <property type="protein sequence ID" value="ABO96159"/>
        <property type="gene ID" value="OSTLU_87388"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87388"/>
    <dbReference type="eggNOG" id="ENOG502QR51">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_682296_0_0_1"/>
    <dbReference type="OMA" id="FAEAFIF"/>
    <dbReference type="OrthoDB" id="201750at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36367">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36367:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="26"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="46723" checksum="AE554C701F63A3C8" modified="2007-05-15" version="1">MKLSRAATPRRVAATPRAAVDAERTVREMYERINARDVDGALACVDENVVYEDFNFPAPFRGKAAVKKLFEESCEGIPDDLTFVIDASTCGGDAVGLTWHVELMGEAFPNARGCSFYRVDETNGKLVYARDCVESPLKPGEASFGIIRLVAPLVKKQIAAKRGEGGGGDGAVETAKSSSSDAGGNALVSAAFWLAGAAYWYVLLLSPSDNPIPGDPAYAIKPETLQEVIAESTDFFFVLPVLNKFGIDALGTAPAVHPVSLGVFNFAEAFIFMLLPLYFMDKRGRDLPTTKMWSIGMFLTNAVLLPYMAIRAATPVRDWNPESNANVDGWRETRLGEKGVMSKLFGGFGLAVGLLSVYWTLFEDPSAGGLSERAAYFNNLMHTDRVSVAFVVDIALVCCWQAYFMKSLDKDSGALAYIPYWGLCIWLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY84</accession>
    <name>A4RY84_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_38656</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418126.1">
        <property type="nucleotide sequence ID" value="XM_001418089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY84"/>
    <dbReference type="STRING" id="436017.A4RY84"/>
    <dbReference type="GeneID" id="5002148"/>
    <dbReference type="Gramene" id="ABO96419">
        <property type="protein sequence ID" value="ABO96419"/>
        <property type="gene ID" value="OSTLU_38656"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38656"/>
    <dbReference type="eggNOG" id="KOG3013">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034114_3_0_1"/>
    <dbReference type="OMA" id="MENIDIH"/>
    <dbReference type="OrthoDB" id="1650at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060149">
        <property type="term" value="P:negative regulation of post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22525">
        <property type="entry name" value="KH-I_Rrp4_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05789">
        <property type="entry name" value="S1_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048565">
        <property type="entry name" value="S1_RRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF4">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21266">
        <property type="entry name" value="S1_RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRP4 S1" evidence="7">
        <location>
            <begin position="100"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="6">
        <location>
            <begin position="194"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37412" checksum="14B7317703DCE1F4" modified="2007-05-15" version="1">MVVSFRDADASTTRAFKRAKRALEQCATASSSARAFVSPGERIPGIDSSEGFLRGHGTRPIAEDNGTDGDGDDDRGLVATTAGVVERVNKLVSVRALKARYAPETGDVVLGRVKEISGKRWILDVNARQNGVLQLSAVHLPGNVQRRRNDVDELNMRMLYAEDDVVSAEVQSVYADGAAALHTRSLKYGCLKNGQLVRVTANLVRRLPQHFHRLKMDEFHDGVAAEANDVEILLGCNGFIWVGAPSGATAPRESEIRREPSDVVDELRELHGDEVSPVQRENISRVANSVRALAELFLPISPPAVMDVFKASSECGVAVRDMLSQGFLTRILEREFEKRVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYG0</accession>
    <name>A4RYG0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418161.1">
        <property type="nucleotide sequence ID" value="XM_001418124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYG0"/>
    <dbReference type="STRING" id="436017.A4RYG0"/>
    <dbReference type="GeneID" id="5002442"/>
    <dbReference type="Gramene" id="ABO96454">
        <property type="protein sequence ID" value="ABO96454"/>
        <property type="gene ID" value="OSTLU_32016"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32016"/>
    <dbReference type="HOGENOM" id="CLU_1477469_0_0_1"/>
    <dbReference type="OrthoDB" id="498951at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="20441" checksum="E6A07F3EAF81B875" modified="2007-05-15" version="1">MRESQPITERLYALRNSALQLAQSGSKDQARMMLEEAYALRKNDVAKNNKDPENTAETLPELIALVHLFETRQDWADDLRAIRREVLKSVRVATDEISADGDAIAAVALLESAVDEYEPFLGEDDECVVAYRADVDAMWTTAGIDPVERDECGDECMANIVGSAGAISMLTEKYTKEIEVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYG6</accession>
    <name>A4RYG6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SDG3513</name>
        <name evidence="3" type="ORF">OSTLU_92854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418163.1">
        <property type="nucleotide sequence ID" value="XM_001418126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYG6"/>
    <dbReference type="STRING" id="436017.A4RYG6"/>
    <dbReference type="GeneID" id="5002266"/>
    <dbReference type="Gramene" id="ABO96456">
        <property type="protein sequence ID" value="ABO96456"/>
        <property type="gene ID" value="OSTLU_92854"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92854"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_428579_0_0_1"/>
    <dbReference type="OMA" id="RESHCAW"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="3"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="639" mass="71491" checksum="4D42B0364F974F82" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYI5</accession>
    <name>A4RYI5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">RNA polymerase sigma-70 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_41331</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418397.1">
        <property type="nucleotide sequence ID" value="XM_001418360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYI5"/>
    <dbReference type="STRING" id="436017.A4RYI5"/>
    <dbReference type="GeneID" id="5002464"/>
    <dbReference type="Gramene" id="ABO96690">
        <property type="protein sequence ID" value="ABO96690"/>
        <property type="gene ID" value="OSTLU_41331"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41331"/>
    <dbReference type="eggNOG" id="ENOG502QVXR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_4_1"/>
    <dbReference type="OMA" id="RVQREFN"/>
    <dbReference type="OrthoDB" id="206108at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06171">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.601.10">
        <property type="entry name" value="RNA Polymerase Primary Sigma Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050239">
        <property type="entry name" value="Sigma-70_RNA_pol_init_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR RPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603:SF47">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR SIGD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="Sigma2 domain of RNA polymerase sigma factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="Sigma3 and sigma4 domains of RNA polymerase sigma factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA polymerase sigma-70" evidence="6">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase sigma-70" evidence="7">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="344" mass="38700" checksum="C3692870EE87962D" modified="2007-05-15" version="1">MSKQLTRTSKRLATDSMRSYLKDIGSVTLLNAGQEVELAKRIQDLMHLESIRENLVEETGPGAEVTDYQWASAAGLNVQALHQRLRDGKSAKNEMIQANLRLVVSIAKKYANSNMSFQDLIQEGCVGLIRGAEKFDFQRGYKFSTYAHWWIRQAVTRSISDQSRTIRLPVHLFEIISRISKMEQKFALHNGRNPTTEEIAAEMDMSAEKITQIKKAAQAPVSLAQTMGGDNKGRTVEDTLVDVTAEGPEKVSGKSLLKEDLENVLNTLNPRERDVLRLRYGLDDGRVKTLEEIGTVFSVTRERIRQIEAKALRKLKQPSRNSILQEYFADSDASSLPKPPPMNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYJ5</accession>
    <name>A4RYJ5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_15689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418404.1">
        <property type="nucleotide sequence ID" value="XM_001418367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYJ5"/>
    <dbReference type="STRING" id="436017.A4RYJ5"/>
    <dbReference type="GeneID" id="5002468"/>
    <dbReference type="Gramene" id="ABO96697">
        <property type="protein sequence ID" value="ABO96697"/>
        <property type="gene ID" value="OSTLU_15689"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15689"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1339466_0_0_1"/>
    <dbReference type="OMA" id="HKACASG"/>
    <dbReference type="OrthoDB" id="567660at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF83">
        <property type="entry name" value="SOCS BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="205" mass="21307" checksum="CE7650540FD009F6" modified="2007-05-15" version="1">MARATACACCARATCATQTLDEIAFDRSACGAAARGDVEALREALARRPASADEDGTTTNASGYTPLHHAARRGCARCVKACLELGCDARATTRAGRGTALHKACAGGRGEACAALLEGGSDAEARDADGENALHKACASGELACVRAVFAHVGMGGRWERMNAARDRRGRAPRDAAATEAIRAFIDERSTAVDERDAALVIHTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYW2</accession>
    <name>A4RYW2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418231.1">
        <property type="nucleotide sequence ID" value="XM_001418194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYW2"/>
    <dbReference type="GeneID" id="5002413"/>
    <dbReference type="Gramene" id="ABO96524">
        <property type="protein sequence ID" value="ABO96524"/>
        <property type="gene ID" value="OSTLU_32164"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32164"/>
    <dbReference type="eggNOG" id="ENOG502SAAX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1380139_0_0_1"/>
    <dbReference type="OrthoDB" id="3863715at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14787">
        <property type="entry name" value="zf-CCHC_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="198" mass="22149" checksum="C6EB05CEF9E3170A" modified="2007-05-15" version="1">MDVHFVYVLECEHDAYYVGVARSVAEHRAGVGSTWTRIHPPRRVAREIAFASRASALEGEDVELKRMMLRHGVDAVRGGSYVCPNLTREQRAALDGEIAHREGRCLRCGRRTHVARDCFARAHVNGYALSAPEGSRSPNRDGRSAVRRCARCGRASHSAPSCFAKFDIDGERLFWGERRSNAESSSSEYESAEETFMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="107" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ93</accession>
    <name>A4RZ93_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_45865</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418291.1">
        <property type="nucleotide sequence ID" value="XM_001418254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ93"/>
    <dbReference type="STRING" id="436017.A4RZ93"/>
    <dbReference type="GeneID" id="5002426"/>
    <dbReference type="Gramene" id="ABO96584">
        <property type="protein sequence ID" value="ABO96584"/>
        <property type="gene ID" value="OSTLU_45865"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45865"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002848_0_0_1"/>
    <dbReference type="OMA" id="EDHRKFG"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="repeat" description="HEAT" evidence="13">
        <location>
            <begin position="133"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="378"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO96584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="923" mass="101038" checksum="AE309FD9E3B7EDAA" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZB8</accession>
    <name>A4RZB8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_41064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418547.1">
        <property type="nucleotide sequence ID" value="XM_001418510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZB8"/>
    <dbReference type="STRING" id="436017.A4RZB8"/>
    <dbReference type="GeneID" id="5002513"/>
    <dbReference type="Gramene" id="ABO96840">
        <property type="protein sequence ID" value="ABO96840"/>
        <property type="gene ID" value="OSTLU_41064"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41064"/>
    <dbReference type="eggNOG" id="KOG1556">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027018_3_0_1"/>
    <dbReference type="OMA" id="HAMSIKT"/>
    <dbReference type="OrthoDB" id="10256771at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005838">
        <property type="term" value="C:proteasome regulatory particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08062">
        <property type="entry name" value="MPN_RPN7_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033858">
        <property type="entry name" value="MPN_RPN7_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF7">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="4">
        <location>
            <begin position="25"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="332" mass="36748" checksum="DCA98C69B67B3BEC" modified="2007-05-15" version="1">MSTPAPSDGATAVAPRAAPASASEVVVHPLVLLSVVDHFRRCDENKRVVGVLLGEQRKGRLDVTSSFAVPFEEDDGDNGIWFLDHSYLENMYRMSKKISAKEKIVGWYSTGPKLRESDIDIHELFYAYTPEPVLVIVDVRAENANIPTSAFAAQIEVKEDGTEKQQKTFVHVPNSIEAFEAEEIGVEHLLRDVKDNTVSTLSTKVSEKVQSLRGLKARLEEIKSYMDKVVDGSLPMNHEIMGHLQDAFNLLPNLNLEDYVKGFNVSTNDAMLVVYLSSLIRSVIALHDLINNKATNKERERALDAPGASDAEKDTDKENEKPKDSGKADAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZJ5</accession>
    <name>A4RZJ5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S5, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS5</name>
        <name evidence="6" type="ORF">OSTLU_12674</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418582.1">
        <property type="nucleotide sequence ID" value="XM_001418545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZJ5"/>
    <dbReference type="STRING" id="436017.A4RZJ5"/>
    <dbReference type="GeneID" id="5002743"/>
    <dbReference type="Gramene" id="ABO96875">
        <property type="protein sequence ID" value="ABO96875"/>
        <property type="gene ID" value="OSTLU_12674"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12674"/>
    <dbReference type="eggNOG" id="KOG3291">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063975_0_0_1"/>
    <dbReference type="OMA" id="KMNIVER"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="37"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="21778" checksum="CAB5871C674C37AD" modified="2007-05-15" version="1">MATTQEVKLFGKWTFDDVEINDISLEDYIAVKPKYAVYVPHTAGRFAAKRFRKAQCPIVERLVNSLMMHGRNNGKKLMAVRIVKHAMEIIHLLTDQNPVQVIVDAIIYAGPREDATRIGSAGVVRRQAVDLSPLRRVNQAIYLLTTGARESAFRNVKTIAECLADELINAAKQSSNSYAIKKKDELERVAKANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S019</accession>
    <name>A4S019_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_2814</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418897.1">
        <property type="nucleotide sequence ID" value="XM_001418860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S019"/>
    <dbReference type="STRING" id="436017.A4S019"/>
    <dbReference type="GeneID" id="5002637"/>
    <dbReference type="Gramene" id="ABO97190">
        <property type="protein sequence ID" value="ABO97190"/>
        <property type="gene ID" value="OSTLU_2814"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2814"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="GHFVDPN"/>
    <dbReference type="OrthoDB" id="18122at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="24"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="250"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="396" mass="43509" checksum="0027A4DC52DB6F40" modified="2007-05-15" version="1" fragment="single">PDYFMDAMKSIGHRRTTPVQRQCWPPACAGSDVLAIAPPGSGKTLGFLLPAIEAALKDHRENPNVGKKRPGAPAVLVVAPTRELTLQISGVCNKLKKAVPVRAVAVYGGASQEEQEEALAQHTSQALLVIGTPGRLLAVLESGALQLDRCAMLVLDEADRMLALGFEEQLSTIREALPDKDSGRQTLLFSATFPKAVRAIGKTWLRKGFETVKIDSEKATVPKDDDDVNVHMAIVEQTVHVCAEHKKSRKLMKYITKLRAEDGRARSRVLVFANRIKTVQFIADLCKRHNEKVSTLHGTMKQNRRDQALKDFKAGKTPVLIATDVAGRGLDIAGLEYVVNWDFPGSIEQYRHRVGRAGRQGKKGAALSFFTRKFTPLASDLVKLLEKDGHFVDPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S022</accession>
    <name>A4S022_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_35349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418899.1">
        <property type="nucleotide sequence ID" value="XM_001418862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S022"/>
    <dbReference type="GeneID" id="5002638"/>
    <dbReference type="Gramene" id="ABO97192">
        <property type="protein sequence ID" value="ABO97192"/>
        <property type="gene ID" value="OSTLU_35349"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35349"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_4_4_1"/>
    <dbReference type="OMA" id="WARDEQW"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF118">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="147"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="475" mass="52724" checksum="1BFE4825DCA37E12" modified="2007-05-15" version="1" fragment="single">MDEWAALASQEGDVEPAELRRYDPAATRKYFSTRPITLLKRGIRSFILLGGFSAKLWLDRKTRGENTSDAKRKEINTKRATQLRNLLVSLGPTYVKLGQVLSSRADLLPAEYIEELRVLQDRVPPFDDDLARRILDRELGPTADRLSLGSTPIASASLGQVYRGTWRNDEGQLEEVAVKVQRPGALVAISLDVGIIRSFAEPWRKWNNLNSDLEGLVDEWGRRFIAELDYEAEATNGENFAKAMASRSDLGGVVTAAPVFRQASTRRVLTTGWIEGVRLQDSKADDTAQLCAVALTSYLAMLLDLGYLHADPHPGNLLRTNDGKLCILDWGLVTPVSKDLSAAILRFIAHLVSKDFEAVPGDLDAMGFIPSELKGVKDPKARRDAFLEAAGTDSKVAQLTKDLEGVQEKYGNIFQIPAYFGYILRAFSVLEGIGLSSDKNYSIANECYPYVARRLLTDKSPETRRALEQLLYGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0A7</accession>
    <name>A4S0A7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TFIIS central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_93034</name>
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    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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            <taxon>Ostreococcus</taxon>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Gramene" id="ABO97231">
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        <property type="gene ID" value="OSTLU_93034"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG1634">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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            <end position="133"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="184"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
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        </location>
    </feature>
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            <end position="494"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO97231.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Duc1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="365"/>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF08588"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="403" mass="45552" checksum="028A6CCD1897FA96" modified="2007-05-15" version="1">METVTAALIVCLLVWLAAVFTRWRTRTRDERGRAPSRWTSESEHRSAPEKASEAMPCADAREIEKSTHERLPRASAPARMLDKKRDVMAKASGHGPPPPPVSRWNQRPLHMTIPSYAGCKITRGALTYNSEIPFEFETSVFAGRCLIRFRDCPPPPAAAAPDAARRLEEYFRGRARTFQCVVQGKFKRRIRADETVTGHEFFQPLLGIPGKRFVKTLVHILRAMNPSLRMSLFARKPQVWTFLGASAQVISIDTPGDEPDITRGSFEENNSKFGGAFASGRLTSAQRRRLLADVKKAKQYSFSTDDVYTFDFYQHVFDPKTFTLNILGLDAFRVDVARHVGDQPPQIMARTSRPGEYLFCFCMWHERALARETNDERPSRAHTSPSPPASPRNPRGASSKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
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    <name>A4S106_OSTLU</name>
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        </recommendedName>
    </protein>
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        <name evidence="8" type="ORF">OSTLU_32932</name>
    </gene>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
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                <person name="Paulsen I."/>
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        </source>
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        </subcellularLocation>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HRDC-like_sf"/>
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    </dbReference>
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        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038846">
        <property type="entry name" value="RPC9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561">
        <property type="entry name" value="CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="7">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="13629" checksum="C61987598B780ADB" modified="2007-05-15" version="1">MRVLGVAEGLLTNVEVLDLLRERAGEPGRLATYPQPHDPFPTEMECYDALRAAPAGAQDRENVRLFIEHIAAIELTQAEVVQLINLKPTERVTVHAVVEKCARRLTEDEVDDLLHLCEKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S193</accession>
    <name>A4S193_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="8">5.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_42345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419325.1">
        <property type="nucleotide sequence ID" value="XM_001419288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S193"/>
    <dbReference type="STRING" id="436017.A4S193"/>
    <dbReference type="GeneID" id="5003274"/>
    <dbReference type="Gramene" id="ABO97618">
        <property type="protein sequence ID" value="ABO97618"/>
        <property type="gene ID" value="OSTLU_42345"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42345"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_1"/>
    <dbReference type="OMA" id="CAPVNPY"/>
    <dbReference type="OrthoDB" id="9402762at2759"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007956">
        <property type="entry name" value="PRK10675.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="9">
        <location>
            <begin position="7"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="352" mass="38104" checksum="8B26325237BDA8C8" modified="2007-05-15" version="1">MDDVRVLVTGGAGYIGTHACVQLLLAGASVVAIDNFDNSCAEAVERVRAIVGERRAARLTFRECDCRDAEALEDVFATCGTVRAVIHFAGLKAVGESVAKPLLYYENNIRSTLTLCETMARHGCKTLCFSSSATVYGEPASVPCTEDFPTAALNPYGRTKLFIEHILSDLQKSDGEWRVALLRYFNPVGAHESGTLGEDPKGIPNNLMPFVQQVAVGRRAELSVFGNDYPTKDGTGRRDYIHVVDLADGHVAAVKKLTTDPNAGLITVNLGTGTSTSVLELVAAFEKASGKKIPCKMVARREGDAAEVYGATQKAFEVLGWRAERTIEDCCKDQWKWASANPYGYLGKPDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1A0</accession>
    <name>A4S1A0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamine amidotransferase type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_33024</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419328.1">
        <property type="nucleotide sequence ID" value="XM_001419291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1A0"/>
    <dbReference type="STRING" id="436017.A4S1A0"/>
    <dbReference type="GeneID" id="5003279"/>
    <dbReference type="Gramene" id="ABO97621">
        <property type="protein sequence ID" value="ABO97621"/>
        <property type="gene ID" value="OSTLU_33024"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33024"/>
    <dbReference type="eggNOG" id="KOG1268">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_479279_0_0_1"/>
    <dbReference type="OMA" id="CIIIKAN"/>
    <dbReference type="OrthoDB" id="7832001at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd01908">
        <property type="entry name" value="YafJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052373">
        <property type="entry name" value="Gamma-glu_amide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187:SF1">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="3">
        <location>
            <begin position="53"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="529" mass="58104" checksum="193E34BE3A2C196A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Q4</accession>
    <name>A4S1Q4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419407.1">
        <property type="nucleotide sequence ID" value="XM_001419370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Q4"/>
    <dbReference type="GeneID" id="5003189"/>
    <dbReference type="Gramene" id="ABO97700">
        <property type="protein sequence ID" value="ABO97700"/>
        <property type="gene ID" value="OSTLU_93156"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93156"/>
    <dbReference type="HOGENOM" id="CLU_2324538_0_0_1"/>
    <dbReference type="OrthoDB" id="498380at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="99" mass="10627" checksum="4AAA7405F64D4E29" modified="2007-05-15" version="1">MSARLASPSGALAPRLRQSPSRPSPVTHRAPRVARASPWSYPDGSNPLEGFFASSSPIDGLGALTGYWYLDVFAGMNVVLLCALALTMDDETFDRRDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S214</accession>
    <name>A4S214_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_42354</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S214"/>
    <dbReference type="STRING" id="436017.A4S214"/>
    <dbReference type="GeneID" id="5003323"/>
    <dbReference type="Gramene" id="ABO97752">
        <property type="protein sequence ID" value="ABO97752"/>
        <property type="gene ID" value="OSTLU_42354"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42354"/>
    <dbReference type="eggNOG" id="ENOG502QQUD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015395_2_1_1"/>
    <dbReference type="OMA" id="CLHIPAH"/>
    <dbReference type="OrthoDB" id="44277at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22753:SF14">
        <property type="entry name" value="MONOACYLGLYCEROL_DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22753">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="4">
        <location>
            <begin position="371"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="631" mass="68666" checksum="6136749854A8EC69" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S240</accession>
    <name>A4S240_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone deacetylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HDA3509</name>
        <name evidence="4" type="synonym">HDA3501</name>
        <name evidence="3" type="ORF">OSTLU_34647</name>
        <name evidence="4" type="ORF">OSTLU_36543</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419469.1">
        <property type="nucleotide sequence ID" value="XM_001419432.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422953.1">
        <property type="nucleotide sequence ID" value="XM_001422916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S240"/>
    <dbReference type="STRING" id="436017.A4S240"/>
    <dbReference type="GeneID" id="5003712"/>
    <dbReference type="GeneID" id="5006921"/>
    <dbReference type="Gramene" id="ABO97762">
        <property type="protein sequence ID" value="ABO97762"/>
        <property type="gene ID" value="OSTLU_34647"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01312">
        <property type="protein sequence ID" value="ABP01312"/>
        <property type="gene ID" value="OSTLU_36543"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34647"/>
    <dbReference type="KEGG" id="olu:OSTLU_36543"/>
    <dbReference type="eggNOG" id="KOG1343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007727_8_2_1"/>
    <dbReference type="OMA" id="CTSPAMG"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09992">
        <property type="entry name" value="HDAC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF11">
        <property type="entry name" value="HISTONE DEACETYLASE 14, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="2">
        <location>
            <begin position="62"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="399" mass="42321" checksum="E069E11E59FCC6D4" modified="2007-05-15" version="1">MARPRVHLTRVAPASPRASRRAERHPSRARRIASASASASASSSPSLLFATSAALEHVQLGHPESNARVPAILDALEAGALTPAARPGEVLEITDVVPATKKALERVHAKNYCNGLELLCATRAPTNLDTAPTYCTPSSFQDVMLGVGAATRLVDEVIDRAKETKEKAPSAFGLIRPPGHHAVPRGAMGFCLVGTAAAAARHAQLRGHKKVLIFDYDVHHGNGTNDIFRDDDSVLFISTHEDGSYPGTGKITDMGEGDGLGATINIPLPPGSGDKAVLSALEEIVVPAAARFQPDFIIVSAGYDAHWRDPLAGLTFRTGTYHRLCTKLKELANEMCGGKIVFLLEGGYDLVGLSEGVADSFRALLGDASTDVGEIPGLRDEPDDKVRNVLTEVKAMHQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2G7</accession>
    <name>A4S2G7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2G7"/>
    <dbReference type="GeneID" id="5003681"/>
    <dbReference type="Gramene" id="ABO98040">
        <property type="protein sequence ID" value="ABO98040"/>
        <property type="gene ID" value="OSTLU_33448"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33448"/>
    <dbReference type="HOGENOM" id="CLU_1117258_0_0_1"/>
    <dbReference type="OMA" id="CEHRRAL"/>
    <dbReference type="OrthoDB" id="10586235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="27544" checksum="991D1D5114BE7930" modified="2007-05-15" version="1">MTDAATRALGRAKELSTTITLALFVLPLGVVAHAAAFAALPMQLASAMLRELTMSRGTDVRALLRGLYALALKPSLAAACAAEIKDDGEIFREYSRSSSEKIEAFRKMSEIEREKFIAACAKLKEEEQIRERLREQLNATRDELKRERAANFAQGKFSKGKEETGSGGVYLTTALLGVMLLYFHDMDTVHTLDKKLAASIPAFWMFVMTFKTRSVQTLCTALNLVLAGYFLHIVLNHRRLLGGEARVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2H0</accession>
    <name>A4S2H0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419749.1">
        <property type="nucleotide sequence ID" value="XM_001419712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2H0"/>
    <dbReference type="GeneID" id="5003646"/>
    <dbReference type="Gramene" id="ABO98042">
        <property type="protein sequence ID" value="ABO98042"/>
        <property type="gene ID" value="OSTLU_16734"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16734"/>
    <dbReference type="HOGENOM" id="CLU_1498722_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="180" mass="19924" checksum="508FDD00D0F73B92" modified="2007-05-15" version="1">MAYAETATAELGAMKSRLEQVERKSEEDARTIDELRARVERATTSTSTSNTDATAGIRAAFEAETRRLGERARVAERERDDALRSLERAVAPRAREESVETPVGGEDASRITEEALLRRRCDDADGLLRQYAAEGAALAEEANEAARRNRVLEAFASDAFALVEDARALVDRRRRERAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Q0</accession>
    <name>A4S2Q0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419788.1">
        <property type="nucleotide sequence ID" value="XM_001419751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Q0"/>
    <dbReference type="GeneID" id="5003777"/>
    <dbReference type="Gramene" id="ABO98081">
        <property type="protein sequence ID" value="ABO98081"/>
        <property type="gene ID" value="OSTLU_16796"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16796"/>
    <dbReference type="HOGENOM" id="CLU_340222_0_0_1"/>
    <dbReference type="OMA" id="KYWFATS"/>
    <dbReference type="OrthoDB" id="10509404at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="811"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="835" mass="91599" checksum="B2F8F581217CBB55" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2U9</accession>
    <name>A4S2U9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Malonyl-CoA:ACP transacylase (MAT) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FabD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419598.1">
        <property type="nucleotide sequence ID" value="XM_001419561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2U9"/>
    <dbReference type="STRING" id="436017.A4S2U9"/>
    <dbReference type="GeneID" id="5003759"/>
    <dbReference type="Gramene" id="ABO97891">
        <property type="protein sequence ID" value="ABO97891"/>
        <property type="gene ID" value="OSTLU_16833"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16833"/>
    <dbReference type="eggNOG" id="KOG2926">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030558_2_0_1"/>
    <dbReference type="OMA" id="LNKTQFT"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052760">
        <property type="entry name" value="Mitochondrial_malonyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170">
        <property type="entry name" value="MALONYL-COA ACP TRANSACYLASE, ACP-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170:SF2">
        <property type="entry name" value="MALONYL-COA:ACP TRANSACYLASE (MAT) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="2">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="290" mass="30278" checksum="8B702E3FFF3EBF31" modified="2007-05-15" version="1">MAKELCEECPAAKAMFDTASGVLGYDLLDVCVNGPAERLNSTAVSQPAIYVSSLAALEKMKMSDEGKAMIDSIDVAAGLSLGEYTALTFAEALSFEDGLKLVKIRGESMQEAADATPSGMASVIGLSADKAEELAARAAAESGAPCSVANYLCNGNYAVSGAIPAIDKVEEIAKPEFKARMVVRLAVAGAFHTDFMAPAADKLKAALEATPIKEPRIPVISNVDVNPHTDAASIRATLAKQLTNPVQWETTMTTLLGKGLESATEVGPGKVISGIMKRVDKAFACDNFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2V4</accession>
    <name>A4S2V4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_33581</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419601.1">
        <property type="nucleotide sequence ID" value="XM_001419564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2V4"/>
    <dbReference type="STRING" id="436017.A4S2V4"/>
    <dbReference type="GeneID" id="5003814"/>
    <dbReference type="Gramene" id="ABO97894">
        <property type="protein sequence ID" value="ABO97894"/>
        <property type="gene ID" value="OSTLU_33581"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33581"/>
    <dbReference type="eggNOG" id="KOG2885">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1743601_0_0_1"/>
    <dbReference type="OMA" id="RIWESTM"/>
    <dbReference type="OrthoDB" id="444809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029190">
        <property type="entry name" value="Rrp14/SURF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007019">
        <property type="entry name" value="SURF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369:SF0">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04935">
        <property type="entry name" value="SURF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="82"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="150" mass="16876" checksum="27AC719557BED542" modified="2007-05-15" version="1">MAFGRITTDDVALNSGRKKKKESKEALLRKVQARQKAIDDAGGEEGGGKAVAEKFAWEAALSRASGEKVLDDPKLLQKSIKREARAKKKSREKWEERTAKVKEQMDAAQTKRKSNIKARKDGKMERKMDKASNKRNRPGFEGRSDGFINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2X8</accession>
    <name>A4S2X8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_33604</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419823.1">
        <property type="nucleotide sequence ID" value="XM_001419786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2X8"/>
    <dbReference type="STRING" id="436017.A4S2X8"/>
    <dbReference type="GeneID" id="5003881"/>
    <dbReference type="Gramene" id="ABO98116">
        <property type="protein sequence ID" value="ABO98116"/>
        <property type="gene ID" value="OSTLU_33604"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33604"/>
    <dbReference type="HOGENOM" id="CLU_800217_0_0_1"/>
    <dbReference type="OMA" id="LCKERTA"/>
    <dbReference type="OrthoDB" id="496934at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="90"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="149"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="238"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="38906" checksum="38A882E35AB000A0" modified="2007-05-15" version="1">MGAALRLPTHTANSNKRQIAQHFAPAIPGVYEPPNDYLHRKNADATTAVLERENERRRSRRSTDDVWCGTSDDEGSARGGLHVSEDHQECGACFEPLCKERTAVFVDESGARTCKHFLHERCARAVCEHIGSVCPICRTAFASARGVPFPTEDANEWFRLCDVDGNGKLDKEQVLTVIRAQIPVDWRKIDKDLGSLWARWDPESSGALGKAQLVGADGLLEFVSKKYPPRLREYKHVPHVTDKRAWFKFWDEDDSGTLEKDEVVRALIKTFGIKDDVAHIQDVRSMVESIWCVFDLDDSGGIDLTEFLLEDGLGDSIMAAFAVDKRAELAQKEDAKASRSPKRPQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S324</accession>
    <name>A4S324_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_34768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419844.1">
        <property type="nucleotide sequence ID" value="XM_001419807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S324"/>
    <dbReference type="STRING" id="436017.A4S324"/>
    <dbReference type="GeneID" id="5003846"/>
    <dbReference type="Gramene" id="ABO98137">
        <property type="protein sequence ID" value="ABO98137"/>
        <property type="gene ID" value="OSTLU_34768"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34768"/>
    <dbReference type="eggNOG" id="KOG0950">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006553_2_0_1"/>
    <dbReference type="OrthoDB" id="2320933at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18026">
        <property type="entry name" value="DEXHc_POLQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046931">
        <property type="entry name" value="HTH_61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048960">
        <property type="entry name" value="POLQ-like_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF6">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20470">
        <property type="entry name" value="HTH_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21099">
        <property type="entry name" value="POLQ_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="171"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="388"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="874" mass="96529" checksum="1C6818746E6E7F2E" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S341</accession>
    <name>A4S341_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419648.1">
        <property type="nucleotide sequence ID" value="XM_001419611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S341"/>
    <dbReference type="GeneID" id="5003518"/>
    <dbReference type="Gramene" id="ABO97941">
        <property type="protein sequence ID" value="ABO97941"/>
        <property type="gene ID" value="OSTLU_93291"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93291"/>
    <dbReference type="eggNOG" id="ENOG502S8W6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_881071_0_0_1"/>
    <dbReference type="OMA" id="APWAYPG"/>
    <dbReference type="OrthoDB" id="513676at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801:SF2">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="316" mass="33525" checksum="E72ED36DACA6F335" modified="2007-05-15" version="1">MSLARARASGPTPARASTSTSTSSSSRARVVALTRRAALVAAVSLVAPGRARADAFADADAFADAGESPAVGACADCIGEYNGYLNSCDRASSSCVSSQNDDAERFVAPWAYEGDRATAMRRLVDVATGRATPRGRALSQRGSGIGARTGDGRARDGLSFVARAEAYDESSGYVRLALAPKTRNDANGGFGAKVALDGNDVDVAGVGVFDAEFLFIANDEVVDVRVAQRGGNAENRGVFRLSYTDGVAFDTNLARARAEELRIAIGWEILPVIAAFDPKWSDKERLWFEKLFDAAAGRPAPETNDLRDMRDTYSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3E9</accession>
    <name>A4S3E9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA ligase</fullName>
            <ecNumber evidence="14">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_16988</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="14"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419907.1">
        <property type="nucleotide sequence ID" value="XM_001419870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3E9"/>
    <dbReference type="STRING" id="436017.A4S3E9"/>
    <dbReference type="GeneID" id="5004221"/>
    <dbReference type="Gramene" id="ABO98200">
        <property type="protein sequence ID" value="ABO98200"/>
        <property type="gene ID" value="OSTLU_16988"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16988"/>
    <dbReference type="eggNOG" id="KOG0967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005138_4_0_1"/>
    <dbReference type="OMA" id="WIKYKRD"/>
    <dbReference type="OrthoDB" id="206088at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07969">
        <property type="entry name" value="OBF_DNA_ligase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3260.10:FF:000001">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000062">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000002">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF4">
        <property type="entry name" value="DNA LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="17">
        <location>
            <begin position="401"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO98200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="664" mass="73716" checksum="9B9572DFA0BA77F6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3G6</accession>
    <name>A4S3G6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS family transporter: multidrug efflux</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_26048</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419913.1">
        <property type="nucleotide sequence ID" value="XM_001419876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3G6"/>
    <dbReference type="GeneID" id="5004048"/>
    <dbReference type="Gramene" id="ABO98206">
        <property type="protein sequence ID" value="ABO98206"/>
        <property type="gene ID" value="OSTLU_26048"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26048"/>
    <dbReference type="eggNOG" id="ENOG502S1B8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039979_0_0_1"/>
    <dbReference type="OMA" id="ACVPASM"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050171">
        <property type="entry name" value="MFS_Transporters"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23517">
        <property type="entry name" value="RESISTANCE PROTEIN MDTM, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="374" mass="38772" checksum="CF542B568764DA25" modified="2007-05-15" version="1">MLTLNLPLGRATDRYGRKPLMMGGMVVMALADVGTAMSRSVAALVPMRMLLGVGRAGCECGDRAYLADLCARVPEKRGIIVAGQSTVHAVGLVIGPLLGGRLMEAYGAPAAFYYVAAAAVGTAIGYSFLPETLTEETREAAELKATMDEEDGGMFEGLNPFMSSDEREELRERKSQRESSSWLTLLANREQRVLLLCASANSLGFVAKLTVIPLYASGHLDASPAEVGNLFSITALLGLATAPLSGLAADKFGKKVVVGAALAACATGLFFGAQSQTQSELIFFIGAWGIGTAAAGPAINALAQELAPKGGEGEALTLPKSAADFIFLIGPLVLGVLDDFIGTDNAGMILCSSAAAIAAASCFFLPAAVERVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3L2</accession>
    <name>A4S3L2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Heat Shock Protein 90, cytosolic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HSP90A</name>
        <name evidence="11" type="ORF">OSTLU_26093</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419938.1">
        <property type="nucleotide sequence ID" value="XM_001419901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3L2"/>
    <dbReference type="STRING" id="436017.A4S3L2"/>
    <dbReference type="GeneID" id="5004069"/>
    <dbReference type="Gramene" id="ABO98231">
        <property type="protein sequence ID" value="ABO98231"/>
        <property type="gene ID" value="OSTLU_26093"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26093"/>
    <dbReference type="eggNOG" id="KOG0019">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006684_1_3_1"/>
    <dbReference type="OMA" id="MRRMKEM"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000012">
        <property type="entry name" value="Heat shock cognate protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="10">
        <location>
            <begin position="28"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="517"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="676"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="101"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="121"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="699" mass="79826" checksum="63409EC71F7285A0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Q1</accession>
    <name>A4S3Q1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419958.1">
        <property type="nucleotide sequence ID" value="XM_001419921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Q1"/>
    <dbReference type="STRING" id="436017.A4S3Q1"/>
    <dbReference type="GeneID" id="5004088"/>
    <dbReference type="Gramene" id="ABO98251">
        <property type="protein sequence ID" value="ABO98251"/>
        <property type="gene ID" value="OSTLU_94845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94845"/>
    <dbReference type="HOGENOM" id="CLU_095113_0_0_1"/>
    <dbReference type="OMA" id="DFRVRIC"/>
    <dbReference type="OrthoDB" id="10492825at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21957" checksum="CC10365B93506588" modified="2007-05-15" version="1">MAIRCMRRVVPEGSLVDGPTKEELRSAPEEFWTLEFKNPTRRSVVARGAASGDGRGGGDDDRANEDEVKGTYTCDEDEVGEFLASSATRFHRAAQSYVVAGDAFDAGDFNVKICRVETSSGQYVGTILDLSYRATNDARTASAALREFAAHATSTANAAAESDDDLGDFVLKDLRESCPLRAYRAPAGDLQCAISYVDAVRALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3S5</accession>
    <name>A4S3S5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_94867</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419971.1">
        <property type="nucleotide sequence ID" value="XM_001419934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3S5"/>
    <dbReference type="STRING" id="436017.A4S3S5"/>
    <dbReference type="GeneID" id="5004010"/>
    <dbReference type="Gramene" id="ABO98264">
        <property type="protein sequence ID" value="ABO98264"/>
        <property type="gene ID" value="OSTLU_94867"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94867"/>
    <dbReference type="eggNOG" id="KOG0333">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_11_4_1"/>
    <dbReference type="OMA" id="IFINYKR"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17945">
        <property type="entry name" value="DEADc_DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057479">
        <property type="entry name" value="PRP28/DDX23-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="186"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="387"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="10">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00037954"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO98264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="575" mass="65011" checksum="1AAE30B6AF48B845" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3X1</accession>
    <name>A4S3X1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_38024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ABO98287"/>
        <property type="gene ID" value="OSTLU_38024"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38024"/>
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    <dbReference type="OrthoDB" id="497650at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:protein ubiquitination"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BB"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
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        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46400">
        <property type="entry name" value="RING/U-BOX SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="42"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="91" mass="9895" checksum="B48D0CFF4959FDDB" modified="2007-05-15" version="1">MTYEELCELGDVVGKVTCGLTDAQIASLPQRTIDASVAGTKCAVCCMEFDAGEDACELPRCGHVYHGECVEPWLKENKSCPTCKTEVFEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Z7</accession>
    <name>A4S3Z7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NFACT RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_88476</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NEMF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Z7"/>
    <dbReference type="STRING" id="436017.A4S3Z7"/>
    <dbReference type="GeneID" id="5003965"/>
    <dbReference type="Gramene" id="ABO98301">
        <property type="protein sequence ID" value="ABO98301"/>
        <property type="gene ID" value="OSTLU_88476"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88476"/>
    <dbReference type="eggNOG" id="KOG2030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003612_1_0_1"/>
    <dbReference type="OMA" id="MFLEFFA"/>
    <dbReference type="OrthoDB" id="207084at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021846">
        <property type="entry name" value="NFACT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11923">
        <property type="entry name" value="NFACT-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="7">
        <location>
            <begin position="542"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein C-terminal" evidence="8">
        <location>
            <begin position="959"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="695"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="743"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="355"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="697"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="752"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="799"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="830"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="880"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="921"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1069" mass="115361" checksum="08C3EFC8A22B1B77" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S456</accession>
    <name>A4S456_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_38163</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO98328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S456"/>
    <dbReference type="STRING" id="436017.A4S456"/>
    <dbReference type="MEROPS" id="M41.018"/>
    <dbReference type="GeneID" id="5003937"/>
    <dbReference type="Gramene" id="ABO98328">
        <property type="protein sequence ID" value="ABO98328"/>
        <property type="gene ID" value="OSTLU_38163"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38163"/>
    <dbReference type="eggNOG" id="KOG0734">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_9_3_1"/>
    <dbReference type="OMA" id="HAINAVS"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000002">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH 11"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="345"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="277"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="752"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO98328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="800" mass="85483" checksum="2D54F965791BC155" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4T1</accession>
    <name>A4S4T1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chalcone isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420321.1">
        <property type="nucleotide sequence ID" value="XM_001420284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4T1"/>
    <dbReference type="GeneID" id="5004565"/>
    <dbReference type="Gramene" id="ABO98614">
        <property type="protein sequence ID" value="ABO98614"/>
        <property type="gene ID" value="OSTLU_26518"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26518"/>
    <dbReference type="eggNOG" id="ENOG502S827">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_892518_0_0_1"/>
    <dbReference type="OMA" id="DRTIPRW"/>
    <dbReference type="OrthoDB" id="18193at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698:SF2">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16036">
        <property type="entry name" value="Chalcone_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chalcone isomerase" evidence="1">
        <location>
            <begin position="207"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="33015" checksum="51725EB711A000CF" modified="2007-05-15" version="1">MLRRALLRSRSSIALNASRALAPSFKARALSTDDDAKAKTRAQAEAEAAKKINAGASPLFSWTEVDVSNADRTIPRWQNAAFVVVVGAFFAYFGNKLTSRAGRRAARGIRAAATDPATKISFPDTNSAGLTVLGAGCRVKRVAIIDVKIYALAMYVDADAARAQKGKGLLNGDYDKELAIELARDVDGKTFMEAMDESLGPRIREIATNMATAEDEDGNFMASVAEAAEKAEEAAVDSLDAMRDGFSSLKLKQGTKMTITWTSNGCAIAVAGAAKMEFESAEFAKALLDVYVGEGPVAPAAAQTFEKGLAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4S501</accession>
    <name>A4S501_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_88658</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420524.1">
        <property type="nucleotide sequence ID" value="XM_001420487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S501"/>
    <dbReference type="STRING" id="436017.A4S501"/>
    <dbReference type="GeneID" id="5004536"/>
    <dbReference type="Gramene" id="ABO98817">
        <property type="protein sequence ID" value="ABO98817"/>
        <property type="gene ID" value="OSTLU_88658"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88658"/>
    <dbReference type="eggNOG" id="KOG0556">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_1_1"/>
    <dbReference type="OMA" id="WVHEIRD"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000132">
        <property type="entry name" value="Aspartyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="185"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO98817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="491" mass="55252" checksum="FA156C5040CCB189" modified="2007-05-15" version="1">MAALQAAPDALAHRYGDAEMVQSKEITGRAWTRVDALNETLKDREVLLRGRVHNVRGKGKSAFIVLRQQTATVQVTLFVDDVNVSKGMVKWASALARESVVDVKGLVVHPEVPIESCTQKEVEVVCREIHCISRSDPELPFLIEDASRPDSAFEAEDTQFVRVLQDTRLNNRVMDLRTPANNAIFKIQSGVGTLFREALLRRNFTEIHTPKLIAGASEGGAAVFKLDYMQVGPACLAQSPQLYKQMAIMGDLEGVFEIGPVFRAEDSNTHRHLCEFTGLDMEMTIKEHYDEVLDVLDELFVSMFDGLNERFKREIGVVNEQHPFEPLQYCRPSLRLTFEEGVKMLQEAGEEVDPLGDIGTETERVLGRLVKEKYGTDFYMLTRYPLNARPFYTMPAPDDPNYTNSFDIFIRGQEIISGAQRIHDPKLLAERAEACGIELPTIQPYIDSFKYGAMPHGGCGVGLERVAMLFLNLPNIRKTSMFPRDPKRLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S577</accession>
    <name>A4S577_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420724.1">
        <property type="nucleotide sequence ID" value="XM_001420687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S577"/>
    <dbReference type="STRING" id="436017.A4S577"/>
    <dbReference type="GeneID" id="5004742"/>
    <dbReference type="Gramene" id="ABO99017">
        <property type="protein sequence ID" value="ABO99017"/>
        <property type="gene ID" value="OSTLU_26664"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26664"/>
    <dbReference type="eggNOG" id="KOG1555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_597712_0_0_1"/>
    <dbReference type="OMA" id="VEMVYVQ"/>
    <dbReference type="OrthoDB" id="497636at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08067">
        <property type="entry name" value="MPN_2A_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="2">
        <location>
            <begin position="201"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="458" mass="51101" checksum="A4EEE37469DE74EA" modified="2007-05-15" version="1">MRRMLELGLVAAGENVLSTTLRKEETLADLKEDGTIVWRRARKIVDPAPVKDEEGGEETAVDAADVETLVFNTVSEFRLAVVREKNPERKVDNGWDWVKYAGVKLGDIKRRLPPEPKPEPKPRAKREPKPTPTPKKRKKITDDERGYHAAVKRIVVPAREKRESRNASKNINIGESFDGQGDLQMVTCEAYNKRRTQPFKVTVTSGAELVMDFHAHLCSDEIIGFLGGVYDDDAKTLRITRALPARQLVQEHAGVEVELDPESVPAIVETLTAKGEGIVGWYHSHPVFATQPSIRDIQNQFEYQKMFARSDGESQTIAPFVGAIVGPYDVRNDSQKSDVRMFHCVDFGGEPEPYELKVEHAGCEDVSPDVLRELKGLADRFRTTPHAGVGDSEPLAAIDLNATPVSLTEHWRDGTTRLEKFEHSLCARLPKSWQDETKTAYVGGIVKYLKTAWGVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5X7</accession>
    <name>A4S5X7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420848.1">
        <property type="nucleotide sequence ID" value="XM_001420811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5X7"/>
    <dbReference type="GeneID" id="5004706"/>
    <dbReference type="Gramene" id="ABO99141">
        <property type="protein sequence ID" value="ABO99141"/>
        <property type="gene ID" value="OSTLU_26916"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26916"/>
    <dbReference type="eggNOG" id="ENOG502QRND">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1020805_0_0_1"/>
    <dbReference type="OMA" id="YSYGYHD"/>
    <dbReference type="OrthoDB" id="1935339at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47361">
        <property type="entry name" value="RING/U-BOX SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47361:SF4">
        <property type="entry name" value="RING_U-BOX SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="28950" checksum="40038F315B9C71FF" modified="2007-05-15" version="1">MSRVAPDDDDARASPTCAVCLARPDARDVALVVACLHAFCASCVTKWAEFTRAGARTRCPLCQASCERVLVRRALDGRALEDGGMQEESLCLLRRARWATRGREGEGWDDGDEDGRDGSDGSDGSDALEEALMRGRARRLVLGNRKFGRGGFVSNGGSRSYARPTASGRGKEPAATAAAKKKPPKHDGEASASPASAPRAVGDDGRRVSARSTSPGKLGPKSAKRAESKQKKQEKEAAKAAARLRRREEEHAAKEAQKAALAAKALEALELAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S663</accession>
    <name>A4S663_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UGP3-like C-terminal hexapeptide repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_88889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420890.1">
        <property type="nucleotide sequence ID" value="XM_001420853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S663"/>
    <dbReference type="STRING" id="436017.A4S663"/>
    <dbReference type="GeneID" id="5005067"/>
    <dbReference type="KEGG" id="olu:OSTLU_88889"/>
    <dbReference type="eggNOG" id="ENOG502QU00">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016716_0_0_1"/>
    <dbReference type="OMA" id="QYGHRCG"/>
    <dbReference type="OrthoDB" id="2020092at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057388">
        <property type="entry name" value="Hexapep_UGP3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF14">
        <property type="entry name" value="UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25441">
        <property type="entry name" value="Hexapep_UGP3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UGP3-like C-terminal hexapeptide repeats" evidence="1">
        <location>
            <begin position="579"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="739" mass="80781" checksum="2A9B834C17425ADE" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6M7</accession>
    <name>A4S6M7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA primase</fullName>
            <ecNumber evidence="10">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_41816</name>
        <name evidence="12" type="ORF">OSTLU_48208</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="10"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420974.1">
        <property type="nucleotide sequence ID" value="XM_001420937.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422920.1">
        <property type="nucleotide sequence ID" value="XM_001422883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6M7"/>
    <dbReference type="STRING" id="436017.A4S6M7"/>
    <dbReference type="GeneID" id="5004973"/>
    <dbReference type="GeneID" id="5006896"/>
    <dbReference type="Gramene" id="ABO99267">
        <property type="protein sequence ID" value="ABO99267"/>
        <property type="gene ID" value="OSTLU_41816"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01279">
        <property type="protein sequence ID" value="ABP01279"/>
        <property type="gene ID" value="OSTLU_48208"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41816"/>
    <dbReference type="KEGG" id="olu:OSTLU_48208"/>
    <dbReference type="eggNOG" id="KOG2851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028288_3_2_1"/>
    <dbReference type="OMA" id="NVTRGFN"/>
    <dbReference type="OrthoDB" id="19606at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.920.10:FF:000003">
        <property type="entry name" value="DNA primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3 10" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP01279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="398" mass="46042" checksum="408A6ABE43296B0B" modified="2007-05-15" version="1">MYRYYKQFYPADLLFKWLAHGNDERHARAEKTYPSRREFCFVLDKEQEEGGGEIFARYQSFVDAKDFKTNVERKKPARIEFGPICNRRPSDRHTVELKPEERELVFDIDMTDYDDVRTCCKEAGICGKCWPLMTVALKVLDVGLREDFGFKHLLWVYSGRRGIHCWISDERARKLSDEARSAVAEYFAVVKGEGQGRRVLSSTPMHPSVKRAYDGVLKQYWIESYLPTQRILEDKTKLEQLLNLIPDENIREDLASEFATSSLNSVDRWGVIERRVQDSLKKNNYKLTGALEKIILWHIYPRVDIEVSRHMNHLLKGPFCVHPKTGRVCVPMDPATADSFNPELVPTVVDLDSGAQTLDGAIKTFNDTFWNACARENIERLTAKTRQAKAEQQSGMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6T6</accession>
    <name>A4S6T6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_278</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Coated pit</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421149.1">
        <property type="nucleotide sequence ID" value="XM_001421112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6T6"/>
    <dbReference type="STRING" id="436017.A4S6T6"/>
    <dbReference type="GeneID" id="5005208"/>
    <dbReference type="Gramene" id="ABO99442">
        <property type="protein sequence ID" value="ABO99442"/>
        <property type="gene ID" value="OSTLU_278"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_278"/>
    <dbReference type="eggNOG" id="KOG1077">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003824_1_0_1"/>
    <dbReference type="OMA" id="PVLMHRY"/>
    <dbReference type="OrthoDB" id="413467at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017104">
        <property type="entry name" value="AP2_complex_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003164">
        <property type="entry name" value="Clathrin_a-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02296">
        <property type="entry name" value="Alpha_adaptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037091">
        <property type="entry name" value="AP2_complex_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="3" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain" evidence="9">
        <location>
            <begin position="751"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="718"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="3"/>
            <end position="4"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="50"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="971" mass="106990" checksum="6DE618DF20233D51" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Z5</accession>
    <name>A4S6Z5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rubisco LSMT substrate-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SDG3508</name>
        <name evidence="5" type="ORF">OSTLU_27297</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421366.1">
        <property type="nucleotide sequence ID" value="XM_001421329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6Z5"/>
    <dbReference type="GeneID" id="5005551"/>
    <dbReference type="Gramene" id="ABO99659">
        <property type="protein sequence ID" value="ABO99659"/>
        <property type="gene ID" value="OSTLU_27297"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27297"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_738491_0_0_1"/>
    <dbReference type="OMA" id="TFRSWLW"/>
    <dbReference type="OrthoDB" id="497755at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF91">
        <property type="entry name" value="PROTEIN SET DOMAIN GROUP 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rubisco LSMT substrate-binding" evidence="4">
        <location>
            <begin position="263"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="375" mass="41358" checksum="3FDB4C1A4D2A6D53" modified="2007-05-15" version="1">MKPTDELALKLLRHRCAGASDAFAPYVASMPARYNLLQTWSEEERAALQDARAETTAKRASEALRKAFEDVKKEVVDIVGEDEREAFALYEWARATVSSRAVSVPFHEAGALCPMGDMFNYAPHDPPILIDVLGAPAFGVNEGNTTSASSREVATDPIPGDGAWDEESKTFAFRAARQPDGRRSIAADEEIFVCYGEYTNLELLEFYGFTLGPNENPQDYYALDVPVDGAETTTSLKVFVGGFDWDDLADARIAFAKKRSSVRMNEKEMRDVARRGGALGRDAEREAFAAIRDAAAARLLSFPTTAKSDEETLLGWKDGSENLKLAITWRLGIKRILQGAYKLAEARRVEMEDVATSAAFAKISLAHVSTPRERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S875</accession>
    <name>A4S875_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421577.1">
        <property type="nucleotide sequence ID" value="XM_001421540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S875"/>
    <dbReference type="STRING" id="436017.A4S875"/>
    <dbReference type="GeneID" id="5005851"/>
    <dbReference type="Gramene" id="ABO99870">
        <property type="protein sequence ID" value="ABO99870"/>
        <property type="gene ID" value="OSTLU_27750"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27750"/>
    <dbReference type="eggNOG" id="ENOG502SFR3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050931_1_0_1"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016718">
        <property type="entry name" value="rRNA_m1G-MeTrfase_A_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018249">
        <property type="entry name" value="MyrA_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="233" mass="24946" checksum="A3AE62EC74C6917A" modified="2007-05-15" version="1">MARKREARSEARAANPNAANPNAASAKVKAKPLRVVDFGCGEGYYSSVVLERARARDDVELELAALDASKDAADLCAAAIGRFARVAVADATRDLPLDDDSVDVAMSVFAPRSPTELARVLRKGGRAVVASPDDDHMVELRDAFRDDDKITVLGVEPNKSTRVDEAFLAAGFDVVFRRAIRDVVPLPADAVADLVFMGPSGFHNPESAIRDAVGDAPRVVTISFNVVVYALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8C2</accession>
    <name>A4S8C2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">starch synthase</fullName>
            <ecNumber evidence="4">2.4.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_40458</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="4"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421741.1">
        <property type="nucleotide sequence ID" value="XM_001421704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8C2"/>
    <dbReference type="STRING" id="436017.A4S8C2"/>
    <dbReference type="CAZy" id="CBM53">
        <property type="family name" value="Carbohydrate-Binding Module Family 53"/>
    </dbReference>
    <dbReference type="CAZy" id="GT5">
        <property type="family name" value="Glycosyltransferase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="5005635"/>
    <dbReference type="Gramene" id="ABP00035">
        <property type="protein sequence ID" value="ABP00035"/>
        <property type="gene ID" value="OSTLU_40458"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40458"/>
    <dbReference type="eggNOG" id="ENOG502QQTU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_18_3_1"/>
    <dbReference type="OMA" id="ALQANCM"/>
    <dbReference type="OrthoDB" id="2018403at2759"/>
    <dbReference type="UniPathway" id="UPA00152"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005085">
        <property type="entry name" value="CBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46083">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46083:SF5">
        <property type="entry name" value="STARCH SYNTHASE 3, CHLOROPLASTIC_AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16760">
        <property type="entry name" value="CBM53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01066">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="8">
        <location>
            <begin position="120"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="680" mass="76174" checksum="79F135FBB0F2D78F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8D5</accession>
    <name>A4S8D5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L21, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL21</name>
        <name evidence="4" type="ORF">OSTLU_27810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421600.1">
        <property type="nucleotide sequence ID" value="XM_001421563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8D5"/>
    <dbReference type="STRING" id="436017.A4S8D5"/>
    <dbReference type="GeneID" id="5005688"/>
    <dbReference type="Gramene" id="ABO99893">
        <property type="protein sequence ID" value="ABO99893"/>
        <property type="gene ID" value="OSTLU_27810"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27810"/>
    <dbReference type="eggNOG" id="KOG1732">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103610_0_1_1"/>
    <dbReference type="OMA" id="INYGDYV"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000002">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="168" mass="19124" checksum="E6E8014A73CC9E33" modified="2007-05-15" version="1">MGNQRARSRGLRHGTRNLFSRGHREHGTLNTTTYLRTFRVGDYVDIKVNSAQQKGMPYLQYQGKTGIVWNVTPRAVGVEINKTIGGRIARKRIHVRVEHVQHSRCREDFIARRAANDKAHHEAKLAGKKIVTKRPVTGAPRTGFALENVKSELLTPIPYDILREGMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8E4</accession>
    <name>A4S8E4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytolic 80S ribosomal protein P1 Cytosolic 60S large ribosomal subunit protein P1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPP1</name>
        <name evidence="7" type="ORF">OSTLU_40742</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the elongation step of protein synthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">P1 and P2 exist as dimers at the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421606.1">
        <property type="nucleotide sequence ID" value="XM_001421569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8E4"/>
    <dbReference type="STRING" id="436017.A4S8E4"/>
    <dbReference type="GeneID" id="5005644"/>
    <dbReference type="Gramene" id="ABO99899">
        <property type="protein sequence ID" value="ABO99899"/>
        <property type="gene ID" value="OSTLU_40742"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40742"/>
    <dbReference type="eggNOG" id="KOG1762">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114656_1_0_1"/>
    <dbReference type="OMA" id="NVWADVY"/>
    <dbReference type="OrthoDB" id="2194681at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05831">
        <property type="entry name" value="Ribosomal_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="104" mass="10300" checksum="5F14371DCB32BB27" modified="2007-05-15" version="1">MSGDLACTYAALILHDDGQEVTADKISAVVSASGLELEPYWSGLFAKFLEQKSVGDLISNVGAGGGGGGGGGAAAGGDAGGDAAAAAPEEEEEEEAEMDFDLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8J7</accession>
    <name>A4S8J7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_18387</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421635.1">
        <property type="nucleotide sequence ID" value="XM_001421598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8J7"/>
    <dbReference type="STRING" id="436017.A4S8J7"/>
    <dbReference type="GeneID" id="5005744"/>
    <dbReference type="Gramene" id="ABO99928">
        <property type="protein sequence ID" value="ABO99928"/>
        <property type="gene ID" value="OSTLU_18387"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18387"/>
    <dbReference type="eggNOG" id="KOG2755">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026335_0_0_1"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050260">
        <property type="entry name" value="FAD-bd_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429:SF2">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="45"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="327"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="279"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="574" mass="60719" checksum="27E5349769044252" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9L3</accession>
    <name>A4S9L3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_6465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422087.1">
        <property type="nucleotide sequence ID" value="XM_001422050.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9L3"/>
    <dbReference type="GeneID" id="5006248"/>
    <dbReference type="Gramene" id="ABP00404">
        <property type="protein sequence ID" value="ABP00404"/>
        <property type="gene ID" value="OSTLU_6465"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6465"/>
    <dbReference type="eggNOG" id="ENOG502QVJY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066532_1_0_1"/>
    <dbReference type="OMA" id="DADYIPM"/>
    <dbReference type="OrthoDB" id="496180at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04873">
        <property type="entry name" value="ACT_UUR-ACR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040217">
        <property type="entry name" value="ACR1-12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31096:SF60">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN ACR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31096">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN ACR4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="143"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23666" checksum="DF506ABD724243FE" modified="2007-05-15" version="1" fragment="single">GGASVGTEKPVPIVIIDNKSDAFATVVEVSFGNYLGELLDTVAALKNLGLDINKGDVQMSGDSTKTSKFYVIDRENGEKVTKSERLEEIRQTILTNMMAFHPEAAEYIQAKAPTRAGGEGVLGKVKKKVQTGIKCAPERYHSKLEIETTDRPGLLVDVVRTLKDLSLCVVSAEVDTIGDKASDIIYVTHKGGPLSPPMEQLVVNSLSYYLSLTEEESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9X7</accession>
    <name>A4S9X7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Multidrug-efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_28350</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422248.1">
        <property type="nucleotide sequence ID" value="XM_001422211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9X7"/>
    <dbReference type="STRING" id="436017.A4S9X7"/>
    <dbReference type="GeneID" id="5006202"/>
    <dbReference type="Gramene" id="ABP00565">
        <property type="protein sequence ID" value="ABP00565"/>
        <property type="gene ID" value="OSTLU_28350"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28350"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_5_3_1"/>
    <dbReference type="OMA" id="PMGLQFS"/>
    <dbReference type="OrthoDB" id="496128at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13133">
        <property type="entry name" value="MATE_like_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050222">
        <property type="entry name" value="MATE_MdtK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048279">
        <property type="entry name" value="MdtK-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43298:SF2">
        <property type="entry name" value="FMN_FAD EXPORTER YEEO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43298">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN NORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="253"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="428" mass="45273" checksum="4C3AFFC67821AD4C" modified="2007-05-15" version="1">MGGMASQNVLNLADAAMVGRLGTASVAAVGLGSTMNFQCQAALQGVASGVQAMAARRMGEGRYDEVARPLNAALILVCLMGVPLAILAFVYADALVPLYTTDASVVANAVPYLRARVLAVPAVGINFAFRGFWNAIQQPQVYMNTLIVMHTVNFTLSLILTFVGVPQLGVPPLGALGAGLGTSFSIWCGTAMYMYQGMKRATKLGFLQKRPTMADLRVLATQALPTSVTNLLYASGMMTLYSIVGRLGTTEVAAVNVLINLMLFLILPCMGMGLAAGALSGRALGRGDVEDAKQWPWDVAKITALLMSVVGFGLALCPRVVLGVFLTDPHAVDIAVTPLRMTGLTVCGDAVSLTMQNALLGVGDAKRVALVSILSQWALFLPSAYLAVAVFDQNLTVVWTLYVAYRFIQGLVYANIWRGGAWAKIKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAF4</accession>
    <name>A4SAF4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator of RNA polymerase II transcription subunit 31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_9356</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422377.1">
        <property type="nucleotide sequence ID" value="XM_001422340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAF4"/>
    <dbReference type="STRING" id="436017.A4SAF4"/>
    <dbReference type="GeneID" id="5006435"/>
    <dbReference type="Gramene" id="ABP00694">
        <property type="protein sequence ID" value="ABP00694"/>
        <property type="gene ID" value="OSTLU_9356"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9356"/>
    <dbReference type="eggNOG" id="KOG4086">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071681_5_2_1"/>
    <dbReference type="OMA" id="QGILNQP"/>
    <dbReference type="OrthoDB" id="10257739at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1340">
        <property type="entry name" value="Mediator of RNA polymerase II, submodule Med31 (Soh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038089">
        <property type="entry name" value="Med31_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008831">
        <property type="entry name" value="Mediator_Med31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13186">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05669">
        <property type="entry name" value="Med31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="96" mass="11809" checksum="F886D1C8118FE111" modified="2007-05-15" version="1" fragment="single">DAVTNEDRFTVELEFVQSLANPRYVHFLASKGVLRDDRFIAYLRYLRYWERPEYAKFILYPHCLRFRRLLLDDAFRVAMENPRNAERAFKAQFERW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAG2</accession>
    <name>A4SAG2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">superoxide dismutase</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CSD1</name>
        <name evidence="13" type="ORF">OSTLU_28559</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422430.1">
        <property type="nucleotide sequence ID" value="XM_001422393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAG2"/>
    <dbReference type="STRING" id="436017.A4SAG2"/>
    <dbReference type="GeneID" id="5006487"/>
    <dbReference type="Gramene" id="ABP00747">
        <property type="protein sequence ID" value="ABP00747"/>
        <property type="gene ID" value="OSTLU_28559"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28559"/>
    <dbReference type="eggNOG" id="KOG0441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056632_1_0_1"/>
    <dbReference type="OMA" id="IVAHEGC"/>
    <dbReference type="OrthoDB" id="2015551at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071484">
        <property type="term" value="P:cellular response to light intensity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071457">
        <property type="term" value="P:cellular response to ozone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071472">
        <property type="term" value="P:cellular response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071329">
        <property type="term" value="P:cellular response to sucrose stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071493">
        <property type="term" value="P:cellular response to UV-B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035195">
        <property type="term" value="P:miRNA-mediated post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046688">
        <property type="term" value="P:response to copper ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010039">
        <property type="term" value="P:response to iron ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.200:FF:000003">
        <property type="entry name" value="Superoxide dismutase [Cu-Zn], chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="9" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="12">
        <location>
            <begin position="51"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="197" mass="19866" checksum="6A71B64963E8BA46" modified="2007-05-15" version="1">MQTLSRSATLASKTHLCGAKSTKTSAHRPRAVAVTAEQKQAVCVLTGTAGVSGVLKLSQSGDAPTKVVGSITGLAPGKHGLHIHEFGDTTNGCMSTGPHFNPNKMDHGAPTDATRHAGDLGNVEATAGGCDFVIEDSQIPLSGANSIIGRAFVIHELEDDLGKGDSSEIGTQGKTSKTTGNAGARLACGVLALAPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAL7</accession>
    <name>A4SAL7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial</fullName>
            <ecNumber evidence="20">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">OSTLU_29304</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 20">Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 20">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="18">Flavinylated by SdhE, about 5% flavinylation occurs in the absence of SdhE.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 20">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 20">Mitochondrion inner membrane</location>
            <topology evidence="1 20">Peripheral membrane protein</topology>
            <orientation evidence="1 20">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="20"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422453.1">
        <property type="nucleotide sequence ID" value="XM_001422416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAL7"/>
    <dbReference type="STRING" id="436017.A4SAL7"/>
    <dbReference type="GeneID" id="5006691"/>
    <dbReference type="Gramene" id="ABP00770">
        <property type="protein sequence ID" value="ABP00770"/>
        <property type="gene ID" value="OSTLU_29304"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29304"/>
    <dbReference type="eggNOG" id="KOG2403">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_6_1_1"/>
    <dbReference type="OMA" id="PTGIWRM"/>
    <dbReference type="OrthoDB" id="71672at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045273">
        <property type="term" value="C:respiratory chain complex II (succinate dehydrogenase)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000001">
        <property type="entry name" value="Mitochondrial succinate dehydrogenase flavoprotein subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.80.40:FF:000002">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000482">
        <property type="entry name" value="Succinate dehydrogenase complex, subunit A, flavoprotein (Fp)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.100:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase flavoprotein subunit (SdhA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.100">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.40">
        <property type="entry name" value="succinate dehydrogenase protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011281">
        <property type="entry name" value="Succ_DH_flav_su_fwd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01816">
        <property type="entry name" value="sdhA_forward"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF51">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000171">
        <property type="entry name" value="SDHA_APRA_LASPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 20" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 18 20" id="KW-0274">FAD</keyword>
    <keyword evidence="6 18 20" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 20" id="KW-0813">Transport</keyword>
    <keyword evidence="5 20" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="21">
        <location>
            <begin position="51"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal" evidence="22">
        <location>
            <begin position="501"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="56"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="445"/>
            <end position="446"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Tele-8alpha-FAD histidine" evidence="19">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00059077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000171-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ABP00770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="633" mass="68342" checksum="1662B8CC27D3308D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBA5</accession>
    <name>A4SBA5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRPL20</name>
        <name evidence="8" type="ORF">OSTLU_19091</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422740.1">
        <property type="nucleotide sequence ID" value="XM_001422703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBA5"/>
    <dbReference type="STRING" id="436017.A4SBA5"/>
    <dbReference type="GeneID" id="5006643"/>
    <dbReference type="Gramene" id="ABP01057">
        <property type="protein sequence ID" value="ABP01057"/>
        <property type="gene ID" value="OSTLU_19091"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19091"/>
    <dbReference type="eggNOG" id="KOG4707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123265_0_1_1"/>
    <dbReference type="OMA" id="CYRIAIR"/>
    <dbReference type="OrthoDB" id="10251781at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.20:FF:000001">
        <property type="entry name" value="50S ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="entry name" value="Ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_bL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_bL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049946">
        <property type="entry name" value="RIBOSOMAL_L20_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_bL20_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="Ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP01057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="110" mass="13077" checksum="414EE33E1D741311" modified="2007-05-15" version="1">MAIKDKIFKAAKGFRGRAKSCVKIARNRVEKAWQYQYRDRRNKKRDWRALWITRINAATREHGVRYNEFINSLTAENVCVDRKILAELAVNEPKSFKALVDRVRYMRGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBD2</accession>
    <name>A4SBD2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_94111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422596.1">
        <property type="nucleotide sequence ID" value="XM_001422559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBD2"/>
    <dbReference type="GeneID" id="5006813"/>
    <dbReference type="Gramene" id="ABP00913">
        <property type="protein sequence ID" value="ABP00913"/>
        <property type="gene ID" value="OSTLU_94111"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94111"/>
    <dbReference type="HOGENOM" id="CLU_395059_0_0_1"/>
    <dbReference type="OMA" id="LECAFAH"/>
    <dbReference type="OrthoDB" id="10642219at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008709">
        <property type="entry name" value="Neurochondrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109:SF7">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="698" mass="76510" checksum="17987A6EA1817638" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBG0</accession>
    <name>A4SBG0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1499 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_7768</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422770.1">
        <property type="nucleotide sequence ID" value="XM_001422733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBG0"/>
    <dbReference type="GeneID" id="5006668"/>
    <dbReference type="Gramene" id="ABP01087">
        <property type="protein sequence ID" value="ABP01087"/>
        <property type="gene ID" value="OSTLU_7768"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7768"/>
    <dbReference type="eggNOG" id="ENOG502QPJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105603_0_0_1"/>
    <dbReference type="OMA" id="WESEDII"/>
    <dbReference type="OrthoDB" id="41501at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801:SF2">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026426">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP01087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15673" checksum="5F4D3D4FA1A98FDF" modified="2007-05-15" version="1" fragment="single">LALCPSTPNCVGTADEFNDTLHYIPAWTYNDEEKIARGGAAKTTSEAMQELVDVTLTTDCDGFTPTIVERTDDYLRLEYKSKIFGFVDDVEFWFPKDVGNSKSRVDYRSASRLGQSDGDANRKRIKTLRLALSKYGWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBH3</accession>
    <name>A4SBH3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Armadillo-like repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_5359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422775.1">
        <property type="nucleotide sequence ID" value="XM_001422738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBH3"/>
    <dbReference type="STRING" id="436017.A4SBH3"/>
    <dbReference type="GeneID" id="5006832"/>
    <dbReference type="Gramene" id="ABP01092">
        <property type="protein sequence ID" value="ABP01092"/>
        <property type="gene ID" value="OSTLU_5359"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5359"/>
    <dbReference type="eggNOG" id="KOG0154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1357751_0_0_1"/>
    <dbReference type="OMA" id="AYSCYKV"/>
    <dbReference type="OrthoDB" id="1716611at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055241">
        <property type="entry name" value="Armadillo_rpt_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36793">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36793:SF1">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22915">
        <property type="entry name" value="ARMH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Armadillo-like repeats" evidence="1">
        <location>
            <begin position="61"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="202" mass="22739" checksum="3989B85FDD185EF6" modified="2007-05-15" version="1" fragment="single">FLASTFAYSCYKVFRKATSGRMRRKRTVNKNVEVVERLKNFFPNERSSVNKGVVRGLALKTGYSSAEIFRKYLRYKLTEEAFTLDFVADVLALKGACGLDSEEMKEILLETGERMFKKYGTLMTNLAGLTQSGMERKIDGAGKFAKLMYLADLDEFIDKAHGAEVQLKLKETFGATDDDYNKLRITALGSDEVDVSSLNSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQI2</accession>
    <name>A4RQI2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_3538</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415393.1">
        <property type="nucleotide sequence ID" value="XM_001415356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQI2"/>
    <dbReference type="GeneID" id="4999426"/>
    <dbReference type="Gramene" id="ABO93685">
        <property type="protein sequence ID" value="ABO93685"/>
        <property type="gene ID" value="OSTLU_3538"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3538"/>
    <dbReference type="eggNOG" id="KOG2383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008681_0_3_1"/>
    <dbReference type="OMA" id="ECYDRRV"/>
    <dbReference type="OrthoDB" id="497816at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040713">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF26">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="35946" checksum="B30D362B410A10AA" modified="2007-05-15" version="1" fragment="single">GAYVHGGPGSGKTFVMDLFYATLDGEHGVEKRREHFHSFMLETHTQLHKLKDSDKNMDTVGQYASALARKMRVLCLDEFQIVDVADAMIIKRLLENLWAEGVLVVTTSNRHPDELYKNGLNRAQFLPCIAEIKRRCIVHEMASDRDYRLTGRARSEEDQAMWKSGGDEAERERWLVERLQVLAGERSFKPLQIAIGGRLVHVRRAGGGIAHFDFNELCDSALGAADYTALASIFNSIGVGHVPTLSSDRLDLVRRFITFIDVMYEHKVKLLVSADASPEELYRASAGDGSRKNAARDEEFAWDRAASRLAEMQSKEFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQM6</accession>
    <name>A4RQM6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_13626</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415759.1">
        <property type="nucleotide sequence ID" value="XM_001415722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQM6"/>
    <dbReference type="GeneID" id="4999428"/>
    <dbReference type="Gramene" id="ABO94051">
        <property type="protein sequence ID" value="ABO94051"/>
        <property type="gene ID" value="OSTLU_13626"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13626"/>
    <dbReference type="eggNOG" id="KOG4561">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088054_0_0_1"/>
    <dbReference type="OMA" id="PMMYLYF"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672938" description="TLC domain-containing protein" evidence="7">
        <location>
            <begin position="30"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="219" mass="24849" checksum="ED3B816331E88FA3" modified="2007-05-15" version="1">MDFGVRCASSAWGLLCGVWSAALLRKALKTSTDTLSRMYASPPLEGCEELVCLAVGYFMYDAIVSHKHYGMQYFLHAVISVVTFLAPQFMPKGFLHMYAANFLLWEATLPFLAARYIMIKAGMGSTRVFKIVELTGFGLWVFIRFFIGVPMMYLYFSDAYSMFKAGKASPLWLYIWYTFASAALQLMNVIWLTAIIKTLFTKSRTTVTPENFGQNNKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQS1</accession>
    <name>A4RQS1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">R3H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415435.1">
        <property type="nucleotide sequence ID" value="XM_001415398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQS1"/>
    <dbReference type="GeneID" id="4999815"/>
    <dbReference type="Gramene" id="ABO93727">
        <property type="protein sequence ID" value="ABO93727"/>
        <property type="gene ID" value="OSTLU_13657"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13657"/>
    <dbReference type="HOGENOM" id="CLU_1241865_0_0_1"/>
    <dbReference type="OrthoDB" id="5979509at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02325">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="2">
        <location>
            <begin position="65"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="223" mass="24407" checksum="4E98EA5BFD1CAD37" modified="2007-05-15" version="1">MKRPGIARADARDAPSTSSDAIDARAAKKARANAAGGLLASILGDVKRSNAQRAKTVVASGGRAITRDDVVSRETKAMEARRKFEREVRERIEREVAGSESAEAFCEFETMEKQWRNIVHEIAAEMKLFSESVEVGATGEEKFVIVHKKAPEVERDAESLRNEIAARERAGKHGKKGEGLSDKAPTYAADAVELTVVGTVKRDLRSVEETIADMRKAREKTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQZ5</accession>
    <name>A4RQZ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_28837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415815.1">
        <property type="nucleotide sequence ID" value="XM_001415778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQZ5"/>
    <dbReference type="GeneID" id="4999470"/>
    <dbReference type="Gramene" id="ABO94107">
        <property type="protein sequence ID" value="ABO94107"/>
        <property type="gene ID" value="OSTLU_28837"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28837"/>
    <dbReference type="eggNOG" id="ENOG502S5G7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171407_0_0_1"/>
    <dbReference type="OMA" id="MQPMRKL"/>
    <dbReference type="OrthoDB" id="512750at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_bL35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36400">
        <property type="entry name" value="RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36400:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="113" mass="12353" checksum="9C3F07A0EA2735C0" modified="2007-05-15" version="1">MVTATTARAATATATATATATARSSIGGVAARRAYARKVKVGANGKTKVKIKPYSSYKGRFQVTASGKILRKRKGKRHCAFAKTPKQRMRLRSSTLVHETLMQPMRKLGFKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR01</accession>
    <name>A4RR01_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_9781</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ELOF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415818.1">
        <property type="nucleotide sequence ID" value="XM_001415781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR01"/>
    <dbReference type="STRING" id="436017.A4RR01"/>
    <dbReference type="GeneID" id="5000060"/>
    <dbReference type="Gramene" id="ABO94110">
        <property type="protein sequence ID" value="ABO94110"/>
        <property type="gene ID" value="OSTLU_9781"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9781"/>
    <dbReference type="eggNOG" id="KOG3214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105983_2_0_1"/>
    <dbReference type="OMA" id="CLDANKK"/>
    <dbReference type="OrthoDB" id="445983at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.190:FF:000001">
        <property type="entry name" value="Transcription elongation factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="80" mass="8957" checksum="C8ABD5D9137FA110" modified="2007-05-15" version="1" fragment="single">MGKRKSSKPPPKKVAPKVDTTFTCPFCNHDKSVFARLDHVAEKGLVECGTCGQKYTCNITHLSEPIDVYSDWIDACERIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRC9</accession>
    <name>A4RRC9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_92151</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415878.1">
        <property type="nucleotide sequence ID" value="XM_001415841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRC9"/>
    <dbReference type="GeneID" id="4999681"/>
    <dbReference type="Gramene" id="ABO94170">
        <property type="protein sequence ID" value="ABO94170"/>
        <property type="gene ID" value="OSTLU_92151"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92151"/>
    <dbReference type="eggNOG" id="KOG1609">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077321_0_0_1"/>
    <dbReference type="OMA" id="GYQYNLE"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065:SF3">
        <property type="entry name" value="FI20425P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
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    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
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        <location>
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        </location>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="313" mass="36180" checksum="1D23F897721B2DF0" modified="2007-05-15" version="1" fragment="single">VEERRAREREDENVARASRAAREIRATTNDDDDDDDDDERLCRICFSGEDGGRLFSPCRCRGSMALVHVECLNEWRNLSRNPRSFYGCDQCGYQYNLERTRAARYLEREEPALVFAVVGVFLLTLFVAALCRAASHGAFLIMTRVRQFLQARNMLRSRPSIDRILAELTMKRVQTHRGVTLHASTCYVEVFFYRLVRWIPPWRDLRRADSWFHAPRIIAIHEYLDFFTGGYLMVGLLAFIVSMYNKIQVQGIRRVAEFVGPSFAFVFAANGLKGARLPLFAGSLYAYAKLHEYTKLKSRALLMRIGQRVLEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRE7</accession>
    <name>A4RRE7_OSTLU</name>
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        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_8481</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415850.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="olu:OSTLU_8481"/>
    <dbReference type="eggNOG" id="KOG0550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OMA" id="DKISHMN"/>
    <dbReference type="OrthoDB" id="513584at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45181">
        <property type="entry name" value="HEAT SHOCK PROTEIN DNAJ WITH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="93"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="161" mass="18293" checksum="5F49A8BCD2BFEF82" modified="2007-05-15" version="1" fragment="single">LNEFLNALADCGRALALNPWNIKALSRRATLHESIRCWDDAIRDLRSYVEIAGNAQYDLFATAQERKNALAMATDRLRRLETTKTTQANSQVDMYRILGLDELKDKATQTDIKKAYRALALKYHPDKANRNMPSWAPASELHDDADRLFKLIGETNAQLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
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    <name>A4RRG6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WHIM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_29010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRG6"/>
    <dbReference type="STRING" id="436017.A4RRG6"/>
    <dbReference type="GeneID" id="4999469"/>
    <dbReference type="Gramene" id="ABO93859">
        <property type="protein sequence ID" value="ABO93859"/>
        <property type="gene ID" value="OSTLU_29010"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29010"/>
    <dbReference type="HOGENOM" id="CLU_329109_0_0_1"/>
    <dbReference type="OMA" id="WWELIIP"/>
    <dbReference type="OrthoDB" id="332390at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053271">
        <property type="entry name" value="DDT_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15546">
        <property type="entry name" value="BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN, 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15546:SF2">
        <property type="entry name" value="DDT DOMAIN-CONTAINING PROTEIN DDB_G0282237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="669"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="91"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="311"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO93859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="955" mass="107034" checksum="343E0D3ED132C1A4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSE9</accession>
    <name>A4RSE9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416503.1">
        <property type="nucleotide sequence ID" value="XM_001416466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSE9"/>
    <dbReference type="STRING" id="436017.A4RSE9"/>
    <dbReference type="GeneID" id="5000295"/>
    <dbReference type="Gramene" id="ABO94796">
        <property type="protein sequence ID" value="ABO94796"/>
        <property type="gene ID" value="OSTLU_92336"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92336"/>
    <dbReference type="eggNOG" id="KOG4478">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105221_0_0_1"/>
    <dbReference type="OMA" id="PKYMYDE"/>
    <dbReference type="OrthoDB" id="156886at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009724">
        <property type="entry name" value="TMEM70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045325">
        <property type="entry name" value="TMEM70/TMEM186/TMEM223"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13281">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13281:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06979">
        <property type="entry name" value="TMEM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="230" mass="25189" checksum="D7003884056F9CD5" modified="2007-05-15" version="1">MSSSATRARRLASTAARATSSSARASTAVEGANRARDARRRGTNRGGRRDDDDDDEKDARKRATDATTREAYVAALGDTVRKVKVLSLASLAVTVVGCPTFVELSQPELAFEAKAAVNATVIGFGGFTTALLQWFISPYVRSMRLDASKGTVTARKLKWNASEYETTFAASAMKESESSRPLVSWEADGKHYYVEMGMVPKYMYDELDLARFDDQAKAEAAAREMDEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSH7</accession>
    <name>A4RSH7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416247.1">
        <property type="nucleotide sequence ID" value="XM_001416210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSH7"/>
    <dbReference type="GeneID" id="5000175"/>
    <dbReference type="Gramene" id="ABO94540">
        <property type="protein sequence ID" value="ABO94540"/>
        <property type="gene ID" value="OSTLU_14343"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14343"/>
    <dbReference type="HOGENOM" id="CLU_1172339_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="27080" checksum="9F30CA2F9232213A" modified="2007-05-15" version="1">MVRYRRALDAQMAEMARGRAREAAREASERDARRRRDGGETANRETAEELARRRDEYVAALDRQVAERRERERKRREEEERRDREENERIRRHVEEERAILREKRAMMAARAAALGDDEGDDDDKTRRRRANRITHSPPASPRPASTSASPRAPPSFVAPRAASVDADAGYVPIPEFPEFPEFSQPATTTASSNERTPLTDAAVADLTNVIRELVVEQRELKSRLARAEAALRARIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP0</accession>
    <name>A4RSP0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat Shock Protein 70, chloroplast</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HSP70B</name>
        <name evidence="7" type="ORF">OSTLU_48839</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416211.1">
        <property type="nucleotide sequence ID" value="XM_001416174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP0"/>
    <dbReference type="STRING" id="436017.A4RSP0"/>
    <dbReference type="GeneID" id="5000464"/>
    <dbReference type="Gramene" id="ABO94504">
        <property type="protein sequence ID" value="ABO94504"/>
        <property type="gene ID" value="OSTLU_48839"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48839"/>
    <dbReference type="eggNOG" id="KOG0102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_2_1_1"/>
    <dbReference type="OMA" id="REPHKGI"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10234">
        <property type="entry name" value="ASKHA_NBD_HSP70_DnaK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000014">
        <property type="entry name" value="Chaperone protein DnaK HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000005">
        <property type="entry name" value="Heat shock protein ssb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000001">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003520">
        <property type="entry name" value="PRK05183.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="666"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="695" mass="74524" checksum="F00761B107D6E089" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP6</accession>
    <name>A4RSP6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_48622</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416454.1">
        <property type="nucleotide sequence ID" value="XM_001416417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP6"/>
    <dbReference type="STRING" id="436017.A4RSP6"/>
    <dbReference type="GeneID" id="5000064"/>
    <dbReference type="Gramene" id="ABO94747">
        <property type="protein sequence ID" value="ABO94747"/>
        <property type="gene ID" value="OSTLU_48622"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48622"/>
    <dbReference type="eggNOG" id="KOG3071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048483_0_1_1"/>
    <dbReference type="OMA" id="EFMQNAD"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF126">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="287" mass="33715" checksum="6C472E4BBA849F2A" modified="2007-05-15" version="1">MLRHYWKAWDSIISKVVFSCADWLGWELDPLSPTTSHLPAITSPTPLITSLLVYLVTVVVSYRVLSATTNTKIWDPTWLKASVICHNAFLILLSLYMCIGCIVEAYKSGYKLWGNKFNVNEKQLAFYIYLFYVSKIYEFVDTFIMLLKRNLRQVSFLHVYHHSTISFIWWMIARRAPGGDAYFSAALNSWVHVCMYTYYLLSALIGKNNDKRVKYLWWGRHLTQMQMLQFLCNLLQAVYCAYFSEYPKFLSKILLFYMISLLALFGHFYYSKHIATAKLRKKHTKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSQ8</accession>
    <name>A4RSQ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Rpl36</name>
        <name evidence="6" type="ORF">OSTLU_119615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416206.1">
        <property type="nucleotide sequence ID" value="XM_001416169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSQ8"/>
    <dbReference type="STRING" id="436017.A4RSQ8"/>
    <dbReference type="GeneID" id="5000195"/>
    <dbReference type="Gramene" id="ABO94499">
        <property type="protein sequence ID" value="ABO94499"/>
        <property type="gene ID" value="OSTLU_119615"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119615"/>
    <dbReference type="eggNOG" id="KOG3452">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140672_0_0_1"/>
    <dbReference type="OMA" id="NKGHKTE"/>
    <dbReference type="OrthoDB" id="25649at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1760:FF:000001">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1760">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000509">
        <property type="entry name" value="Ribosomal_eL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038097">
        <property type="entry name" value="Ribosomal_eL36_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10114">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01158">
        <property type="entry name" value="Ribosomal_L36e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01190">
        <property type="entry name" value="RIBOSOMAL_L36E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="105" mass="11684" checksum="62243ED7D11A7FF0" modified="2007-05-15" version="1">MKDNISVGLDKGHAVTKRELAAKPGSRKGRCGKRVGMIRGLIREVAGSAPYEKRLVELLKNGRDKRALKLAKRKLGTHLRAKKKREEMGNLMRKASRKAPAPESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSV4</accession>
    <name>A4RSV4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Luminal binding protein, probable</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Bip</name>
        <name evidence="9" type="ORF">OSTLU_119566</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416181.1">
        <property type="nucleotide sequence ID" value="XM_001416144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSV4"/>
    <dbReference type="STRING" id="436017.A4RSV4"/>
    <dbReference type="GeneID" id="5000229"/>
    <dbReference type="Gramene" id="ABO94474">
        <property type="protein sequence ID" value="ABO94474"/>
        <property type="gene ID" value="OSTLU_119566"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119566"/>
    <dbReference type="eggNOG" id="KOG0100">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_3_0_1"/>
    <dbReference type="OMA" id="DSKPCIE"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000016">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672849" evidence="8">
        <location>
            <begin position="27"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="604"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="662" mass="73271" checksum="493808102DB64DB7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSX8</accession>
    <name>A4RSX8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Pho4</name>
        <name evidence="8" type="ORF">OSTLU_119536</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416412.1">
        <property type="nucleotide sequence ID" value="XM_001416375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSX8"/>
    <dbReference type="STRING" id="436017.A4RSX8"/>
    <dbReference type="GeneID" id="5000286"/>
    <dbReference type="Gramene" id="ABO94705">
        <property type="protein sequence ID" value="ABO94705"/>
        <property type="gene ID" value="OSTLU_119536"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119536"/>
    <dbReference type="eggNOG" id="KOG2493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_3_1_1"/>
    <dbReference type="OMA" id="TLKWYHV"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF96">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="563"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="600" mass="64755" checksum="C2D366B7E1887775" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSZ0</accession>
    <name>A4RSZ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Tho2</name>
        <name evidence="8" type="ORF">OSTLU_119527</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416161.1">
        <property type="nucleotide sequence ID" value="XM_001416124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSZ0"/>
    <dbReference type="STRING" id="436017.A4RSZ0"/>
    <dbReference type="GeneID" id="5000400"/>
    <dbReference type="Gramene" id="ABO94454">
        <property type="protein sequence ID" value="ABO94454"/>
        <property type="gene ID" value="OSTLU_119527"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119527"/>
    <dbReference type="eggNOG" id="KOG1874">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_299639_0_0_1"/>
    <dbReference type="OMA" id="HSAIKHC"/>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="7">
        <location>
            <begin position="59"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="7">
        <location>
            <begin position="314"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="6">
        <location>
            <begin position="434"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="5">
        <location>
            <begin position="732"/>
            <end position="1019"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1039" mass="118498" checksum="32ED44E8F29D6378" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT47</accession>
    <name>A4RT47_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Glk</name>
        <name evidence="3" type="ORF">OSTLU_119474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416380.1">
        <property type="nucleotide sequence ID" value="XM_001416343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT47"/>
    <dbReference type="STRING" id="436017.A4RT47"/>
    <dbReference type="GeneID" id="5000254"/>
    <dbReference type="Gramene" id="ABO94673">
        <property type="protein sequence ID" value="ABO94673"/>
        <property type="gene ID" value="OSTLU_119474"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119474"/>
    <dbReference type="eggNOG" id="ENOG502QSB1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042582_0_0_1"/>
    <dbReference type="OMA" id="NNHWRLS"/>
    <dbReference type="OrthoDB" id="10251652at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24008">
        <property type="entry name" value="ASKHA_NBD_GLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00749">
        <property type="entry name" value="glk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47363">
        <property type="entry name" value="GLUCOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47363:SF1">
        <property type="entry name" value="GLUCOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="367" mass="40008" checksum="B588CA1CF59AC07B" modified="2007-05-15" version="1">MWTNVSTHRKFISRLQNCKQVSFAHRTQTNKPGRRLTMSHSYTIIAADIGGTNARFQAWAISMEGVDDELLFEKTYSTNSFDAFDKCLNVFCHDSGLDHFDSSCFAVAGPVENNCCEMTNLKWQVNGAQVQQSFNIPKVSVLNDFAAVGHGITGLDPSQLAKLNDIEPVQHGPIAIVGPGTGLGEAFLIWNDANEAYSIISTEGSHAPFAPKNEVQIELLKYMWAKNYKVCEVEQVCSGPGLRRIYEFLCKSIHTKPDDIEPAEIATRALANSCKTCRTTLKMFLEILGSECSSAALRVLATGGVYIAGGIPPKILPLLMDGSLTTAFENCNPSMRNVVASFPLIAVKTPNVGLLGAKVLAKRQLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTU8</accession>
    <name>A4RTU8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416559.1">
        <property type="nucleotide sequence ID" value="XM_001416522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTU8"/>
    <dbReference type="STRING" id="436017.A4RTU8"/>
    <dbReference type="GeneID" id="5000883"/>
    <dbReference type="Gramene" id="ABO94852">
        <property type="protein sequence ID" value="ABO94852"/>
        <property type="gene ID" value="OSTLU_92370"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92370"/>
    <dbReference type="eggNOG" id="ENOG502SZ7V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_409626_0_0_1"/>
    <dbReference type="OMA" id="NWRARVE"/>
    <dbReference type="OrthoDB" id="5855668at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U-box" evidence="2">
        <location>
            <begin position="24"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="671" mass="74374" checksum="E56042FC2D44A88C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTW7</accession>
    <name>A4RTW7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_30413</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416857.1">
        <property type="nucleotide sequence ID" value="XM_001416820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTW7"/>
    <dbReference type="GeneID" id="5000822"/>
    <dbReference type="Gramene" id="ABO95150">
        <property type="protein sequence ID" value="ABO95150"/>
        <property type="gene ID" value="OSTLU_30413"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30413"/>
    <dbReference type="eggNOG" id="ENOG502QWKN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_557072_0_0_1"/>
    <dbReference type="OMA" id="MDEHESP"/>
    <dbReference type="OrthoDB" id="497289at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47122">
        <property type="entry name" value="MYB-LIKE DNA-BINDING DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47122:SF8">
        <property type="entry name" value="MYB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="404"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="404"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="505" mass="53400" checksum="8D73E04DDB3A0EBF" modified="2007-05-15" version="1">MATMAPSQTPGCHATRAALRRDGAPGAVRGYRFVNRPDVNGDTDAVDQQMAGFVSEAGPFDADPVLKAAEREILSATKAQRRAAAERGALLEHGYGAMLGTGSGSMGNLGMLTASGGSDDDDKASTQSVAYLSGDAASNRSYSPFDVTLDEAAENLLCEFGAPIMDGAIGLIDDEGAEIFVEHNAPPLSSWMSNGNLCGLVAPNDHEPEWASGGGAHGAYAHVPAVIDFGVPGHTEVESIASLRGQYRALFGKDTNSNNRQWILKRLEAFRNGDDFTPPSSRFSSPLSGEDTLMNVGASRFKPQASPKRAAGKRQVKSARSLYDDDAMDEHESPRRGVAAKGRGGKGAKGKRSAEATLPKSAHKKAKSVSDAESNDGDIGKKGSGRAAGKPAGRGKPGENGTGRRSKHHNPWALEEAEALVRGVAQCGGGKWADIKKLGFTAIEHRTAVDLKDKWRNLLRIAMLPQQSVKTVGDKKREIPQELLAKVRELAAKQAKAKAAAESRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU20</accession>
    <name>A4RU20_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative mitochondrial ribosomal protein L13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MRPL13</name>
        <name evidence="4" type="ORF">OSTLU_8159</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416883.1">
        <property type="nucleotide sequence ID" value="XM_001416846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU20"/>
    <dbReference type="STRING" id="436017.A4RU20"/>
    <dbReference type="GeneID" id="5001114"/>
    <dbReference type="Gramene" id="ABO95176">
        <property type="protein sequence ID" value="ABO95176"/>
        <property type="gene ID" value="OSTLU_8159"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8159"/>
    <dbReference type="eggNOG" id="KOG3203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082184_2_2_1"/>
    <dbReference type="OMA" id="HKPIYTP"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="137" mass="15414" checksum="A96B8A55D3500A40" modified="2007-05-15" version="1" fragment="single">NLRGLRYRLVDARGEVLGRLASRIAVALQGKDKPTYAPGAGSGDVVVVVNAGEVHLTGEKLKKKRYHRHTGYVGGLVTRTAREMFDRDPTWVLRKAVERMLPRCVRSKETMRKLRVFPGAEHAFDESKMSRMEAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU76</accession>
    <name>A4RU76_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_30523</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416623.1">
        <property type="nucleotide sequence ID" value="XM_001416586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU76"/>
    <dbReference type="STRING" id="436017.A4RU76"/>
    <dbReference type="GeneID" id="5001036"/>
    <dbReference type="Gramene" id="ABO94916">
        <property type="protein sequence ID" value="ABO94916"/>
        <property type="gene ID" value="OSTLU_30523"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30523"/>
    <dbReference type="eggNOG" id="KOG4200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_944411_0_0_1"/>
    <dbReference type="OMA" id="NVGMFQV"/>
    <dbReference type="OrthoDB" id="3990054at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23995">
        <property type="entry name" value="Seipin_BSCL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212">
        <property type="entry name" value="BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212:SF0">
        <property type="entry name" value="SEIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="297"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="327" mass="36294" checksum="19D0E0C900DA578D" modified="2007-05-15" version="1">MADEKPTLLEHEWVEFSARVRRVCKRSAALTLSAAIISFGLLIASITCVFALRYIVVPRGPASLSQDLVFDYTAAAPVARVSFIPQKFANTGESKPRKGRIVSAKQNFDVDIEFVVPDSEYNVNVGMFQVNAKLLTPSGKTLLERSRPGIVKYTSKEVKWLKTIVWWPFHALGLIEEQQNVRVAMVQNYKEDSESPFTDIEVTMKPHAGSARLPQIYEARAIVHLSMNFVAKLLYFYPIASSFVLVGLFWSGFSFAAFVSTVISLLIMGSKIDEKDAESPMKPDEIGKYARAIADAMDSAESSQAPAHTTNGMMDEGLRRRNVSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUY3</accession>
    <name>A4RUY3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_86812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417041.1">
        <property type="nucleotide sequence ID" value="XM_001417004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUY3"/>
    <dbReference type="ESTHER" id="ostlu-a4ruy3">
        <property type="family name" value="Haloperoxidase"/>
    </dbReference>
    <dbReference type="GeneID" id="5001123"/>
    <dbReference type="Gramene" id="ABO95334">
        <property type="protein sequence ID" value="ABO95334"/>
        <property type="gene ID" value="OSTLU_86812"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86812"/>
    <dbReference type="eggNOG" id="ENOG502RZTA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_12_0_1"/>
    <dbReference type="OMA" id="HWCYWEK"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046464">
        <property type="term" value="P:acylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF5">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE ABHD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="34"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="312" mass="33908" checksum="797EAE4D6528F22B" modified="2007-05-15" version="1">MPWTALDLDPVDGGRVRLRAVVGGATPARDRPVVVLVHGWSGTAAYWSPAMRAARDDFPATIAFDLRGHGGSDRPGRGHTVARLAMDLREVLEQAAARLSPSGFVLVGASMGCAVVWSLLQLCGARWRVGGGSDATEVSVIGAVLVDQAPLQNRRPDWELGSLGCYDAASYEALAAAVRRDMSTFADGNAEACFHDLSVVDPDVLAMVKSETLECCPEALCELMYDHTHQDWRSECRHMTIPALVLAGRETKIFPIDGIKAVAEMIPDSELKIFENCGHWLYLEEPKKFADEVHDFVTRCDDKQRAATSEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV23</accession>
    <name>A4RV23_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rubisco LSMT substrate-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SDG3515</name>
        <name evidence="6" type="ORF">OSTLU_14780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416768.1">
        <property type="nucleotide sequence ID" value="XM_001416731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV23"/>
    <dbReference type="GeneID" id="5000629"/>
    <dbReference type="Gramene" id="ABO95061">
        <property type="protein sequence ID" value="ABO95061"/>
        <property type="gene ID" value="OSTLU_14780"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14780"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_614812_0_0_1"/>
    <dbReference type="OMA" id="RNDRMFK"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF151">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673013" description="Rubisco LSMT substrate-binding domain-containing protein" evidence="4">
        <location>
            <begin position="29"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Rubisco LSMT substrate-binding" evidence="5">
        <location>
            <begin position="326"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="514" mass="57216" checksum="4C04F545B6D83551" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV69</accession>
    <name>A4RV69_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416790.1">
        <property type="nucleotide sequence ID" value="XM_001416753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV69"/>
    <dbReference type="GeneID" id="5001064"/>
    <dbReference type="Gramene" id="ABO95083">
        <property type="protein sequence ID" value="ABO95083"/>
        <property type="gene ID" value="OSTLU_30867"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30867"/>
    <dbReference type="HOGENOM" id="CLU_1629820_0_0_1"/>
    <dbReference type="OMA" id="RANYGFR"/>
    <dbReference type="OrthoDB" id="2538345at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="18266" checksum="BC89E55E0312504C" modified="2007-05-15" version="1">MSAQFTRAGDPNDDRGPSMMVRHAEQRAREAAANADRYLRETFPRANATTLALALKEFNNDVALAKDALKEFFEEEDGGEERRAELAEARKKDEEARQKEIVARLRAHGDVSVMREQEILRQKLQIAHRVGDASEAERIKALLSVDDALAKAAKSNYGFRPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV87</accession>
    <name>A4RV87_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribodipyrimidine photo-lyase</fullName>
            <ecNumber evidence="3">4.1.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DNA photolyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_30886</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutylpyrimidine dimers (CPDs), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. Required for plant survival in the presence of UV-B light. Not involved in the repair of (6-4) photoproducts.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA).</text>
            <dbReference type="EC" id="4.1.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417095.1">
        <property type="nucleotide sequence ID" value="XM_001417058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV87"/>
    <dbReference type="STRING" id="436017.A4RV87"/>
    <dbReference type="GeneID" id="5001100"/>
    <dbReference type="Gramene" id="ABO95388">
        <property type="protein sequence ID" value="ABO95388"/>
        <property type="gene ID" value="OSTLU_30886"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30886"/>
    <dbReference type="eggNOG" id="KOG0133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026342_2_0_1"/>
    <dbReference type="OMA" id="LIYAYEI"/>
    <dbReference type="OrthoDB" id="494480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009650">
        <property type="term" value="P:UV protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000002">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.80:FF:000004">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000110">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008148">
        <property type="entry name" value="DNA_photolyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032673">
        <property type="entry name" value="DNA_photolyase_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052219">
        <property type="entry name" value="Photolyase_Class-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00591">
        <property type="entry name" value="phr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211:SF0">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTO-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01083">
        <property type="entry name" value="DNA_PHOTOLYASES_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="14">
        <location>
            <begin position="27"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00055119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO95388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="506" mass="56935" checksum="A0BC775BB15CC2B2" modified="2007-05-15" version="1">MPSALCASKKRYRALTRGTKPEAGPNAPVVYWLSRDQRVRDNWALLRACDVARANDAPVVIAFNLLTKFLGAGARQFGFMLRGLRELEGAAKAKNVTFAMTYGDEPAIAIDALAKKIGAKTIVCDFSPLRDGLKWRKELAALCEARSAHCEECDAHNVVPCWEASDKLEVGARTLRGRLAKRYPEFLHEFPEVPDDLPKYSGPALDAVKWDDIIAEALSRGQAVPEVTWAIPGETAAHAVLDDFVNSRMKLYEKRNDPSKPQALSGLSPWLHFGQISGQRCALEAKKAVGKASPPAYESFFEELVVRRELSDNFCYYSPKYDQIEGQKYDWAKDTLRLHASDKRPYLYSLEELERAKTHDDLWNAAQRELRYGGKMHGFCRMYWAKKILEWTESPEQALKFAIYLNDTYSLDGRDPSGYVGCMWSIVGVHDQGWKEREVFGKIRYMAYDSTKKKFSIPDYIARVNALVKAAKADFKSGESSHAANPGLFKINVPAANKRKATEEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV97</accession>
    <name>A4RV97_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_8592</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417101.1">
        <property type="nucleotide sequence ID" value="XM_001417064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV97"/>
    <dbReference type="STRING" id="436017.A4RV97"/>
    <dbReference type="GeneID" id="5000941"/>
    <dbReference type="Gramene" id="ABO95394">
        <property type="protein sequence ID" value="ABO95394"/>
        <property type="gene ID" value="OSTLU_8592"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8592"/>
    <dbReference type="eggNOG" id="KOG3355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070631_3_2_1"/>
    <dbReference type="OMA" id="CKAHFQK"/>
    <dbReference type="OrthoDB" id="17199at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF0">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="93" mass="10538" checksum="56380C7A03F6C2F1" modified="2007-05-15" version="1" fragment="single">PLDVDELGRASWALMHTIAAYYPQKPTHAQRVQARRFFDALGDLYPCATCRADLRADVDAHPPRCESREALAKWVCERHNVVNEKLGKAKMSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVA9</accession>
    <name>A4RVA9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL22c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_8608</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417107.1">
        <property type="nucleotide sequence ID" value="XM_001417070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVA9"/>
    <dbReference type="STRING" id="436017.A4RVA9"/>
    <dbReference type="GeneID" id="5001116"/>
    <dbReference type="Gramene" id="ABO95400">
        <property type="protein sequence ID" value="ABO95400"/>
        <property type="gene ID" value="OSTLU_8608"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8608"/>
    <dbReference type="eggNOG" id="KOG1711">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083987_3_0_1"/>
    <dbReference type="OMA" id="PYRACEK"/>
    <dbReference type="OrthoDB" id="416470at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_uL22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047867">
        <property type="entry name" value="Ribosomal_uL22_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="109" mass="11846" checksum="1CC5FA5A00D082C5" modified="2007-05-15" version="1" fragment="single">ESASAILRGAKGSPKKFSAFLRLVRGLRVDDALIQCDMSPKRVAKTVAKVLQSAIGNAVNNQGLDRERLVVSSATVGKGEYLRRVSIHGRGRAGVMHRPRSHVRVTVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVF8</accession>
    <name>A4RVF8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphofructokinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_37009</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417416.1">
        <property type="nucleotide sequence ID" value="XM_001417379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVF8"/>
    <dbReference type="STRING" id="436017.A4RVF8"/>
    <dbReference type="GeneID" id="5001169"/>
    <dbReference type="Gramene" id="ABO95709">
        <property type="protein sequence ID" value="ABO95709"/>
        <property type="gene ID" value="OSTLU_37009"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37009"/>
    <dbReference type="eggNOG" id="KOG2440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020655_7_1_1"/>
    <dbReference type="OMA" id="ADKWNGY"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000002">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050929">
        <property type="entry name" value="PFKA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012004">
        <property type="entry name" value="PyroP-dep_PFK_TP0108"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005301">
        <property type="entry name" value="PRK06830.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45770">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000534">
        <property type="entry name" value="PPi_PFK_TP0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="11">
        <location>
            <begin position="73"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="433" mass="46388" checksum="3EAE671B285F4182" modified="2007-05-15" version="1">MYGLEKRPSPFAEGGSLWEFGLGQRFIDNRDSVSLNPLRTSYVGGEDTAFSDERAVRAGAREEIYYDPKRVKAAIVTCGGLCPGLNDVIRSITTTLEDYGCEEILGIKYGFRGFFGDEAADANPLEAPMKLTSEMVEDIQITGGSMLGSSRGGADMPAIVQKIEDMGIDFLFVIGGNGSHAGALAIDKLCREKGLTTSVIGVPKTIDNDILLLDRTFGFQTAVDEAVKAIRSANIEARSADNGVGLVRLMGRQSGFIAMHAALASGNTDVCLIPEIDCPLEGDGGVLAHIKRVVERQNHAVVVVAEGAGQEQLGMIGETDASGNPILQNFAKYLQQKLKDAKPECDIKYIDPTYMVRACRTNASDAVYCSILGQNAVHAAFAGLSAVTVGMCSGHYVYLPIPPVISAARTVDPEGRMFERLRFAIGQPTFSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW10</accession>
    <name>A4RW10_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PQ-loop-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_5872</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417502.1">
        <property type="nucleotide sequence ID" value="XM_001417465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW10"/>
    <dbReference type="STRING" id="436017.A4RW10"/>
    <dbReference type="GeneID" id="5001362"/>
    <dbReference type="KEGG" id="olu:OSTLU_5872"/>
    <dbReference type="eggNOG" id="KOG2913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019699_3_0_1"/>
    <dbReference type="OMA" id="LIMNASW"/>
    <dbReference type="OrthoDB" id="497757at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF34">
        <property type="entry name" value="LYSOSOMAL AMINO ACID TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="27946" checksum="7B317A1E7FAD5683" modified="2007-05-15" version="1" fragment="single">LDWIRVTFRECVSDDVQLAGFYLALVTIACWMSAQVPQLVLNYRAKSARGLSPYFLLQWLAGDSFNLIGCVLTGDQAPTQTYTAVYFVLSDLALLCQYTYYERDGARARASASDDEGSVSGPMSPVGGFVLAGAAALALTTMTTNSAGEASNGMLREAMNVTDCDYNANPAWMQSFGRGVGYLATCFYLGGRLAQIAKNRRRRSVEGLSLTMFALAITANVAYGTSVLCASHSRADVIRSLPWLLGSFGTVSLDATILAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW22</accession>
    <name>A4RW22_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31186</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 12">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417510.1">
        <property type="nucleotide sequence ID" value="XM_001417473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW22"/>
    <dbReference type="STRING" id="436017.A4RW22"/>
    <dbReference type="GeneID" id="5001276"/>
    <dbReference type="Gramene" id="ABO95803">
        <property type="protein sequence ID" value="ABO95803"/>
        <property type="gene ID" value="OSTLU_31186"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31186"/>
    <dbReference type="eggNOG" id="KOG0323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_426047_0_0_1"/>
    <dbReference type="OMA" id="HWLECSM"/>
    <dbReference type="OrthoDB" id="498731at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="305"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="550"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="110"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="643" mass="70789" checksum="38E79D5397593680" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW72</accession>
    <name>A4RW72_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_49448</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417276.1">
        <property type="nucleotide sequence ID" value="XM_001417239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW72"/>
    <dbReference type="STRING" id="436017.A4RW72"/>
    <dbReference type="GeneID" id="5001220"/>
    <dbReference type="Gramene" id="ABO95569">
        <property type="protein sequence ID" value="ABO95569"/>
        <property type="gene ID" value="OSTLU_49448"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49448"/>
    <dbReference type="eggNOG" id="KOG0828">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065942_0_0_1"/>
    <dbReference type="OMA" id="GPRCFIP"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF162">
        <property type="entry name" value="TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="221"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO95569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="31211" checksum="B82A44F2703D1AE7" modified="2007-05-15" version="1">MRMSLASIGMRSVVDSYLCLAHLTGGILVDDLFMPLALVALCYFVLFSILEMRLLIAAWRARTPDITNWIELRVNLGAVYSRFYAGFISGLFAMYWLSDRFIIFLLLANSYWVPQIVRNAYHNHRQALKPWYVVTTSFMRLSAPLYVLGCPSNFLKIRPNYFHCAVMVAWTTAQTAMLLAQYYINPRYGFPIGIFPEVYDYHRKARERDVEMGDVAAGPDCVICMNPVKFRAVHDRMVTPCNHFFHTKCLMRWMDIKQECPTCRGALPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW98</accession>
    <name>A4RW98_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417289.1">
        <property type="nucleotide sequence ID" value="XM_001417252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW98"/>
    <dbReference type="GeneID" id="5001285"/>
    <dbReference type="Gramene" id="ABO95582">
        <property type="protein sequence ID" value="ABO95582"/>
        <property type="gene ID" value="OSTLU_31262"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31262"/>
    <dbReference type="HOGENOM" id="CLU_3017637_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="56" mass="6133" checksum="E77A18A11088C786" modified="2007-05-15" version="1">MVLSKGKFKVASKVRGKDIDALSAEEVQRVQDAVLGEYAGTLALEEKQRIDAGTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="121" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWJ6</accession>
    <name>A4RWJ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 16">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="11 16">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">OSTLU_87099</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 16">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11 16"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417342.1">
        <property type="nucleotide sequence ID" value="XM_001417305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWJ6"/>
    <dbReference type="STRING" id="436017.A4RWJ6"/>
    <dbReference type="GeneID" id="5001563"/>
    <dbReference type="Gramene" id="ABO95635">
        <property type="protein sequence ID" value="ABO95635"/>
        <property type="gene ID" value="OSTLU_87099"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87099"/>
    <dbReference type="eggNOG" id="KOG0944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009884_1_0_1"/>
    <dbReference type="OMA" id="FVPCEHT"/>
    <dbReference type="OrthoDB" id="361536at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02658">
        <property type="entry name" value="Peptidase_C19B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000086">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000396">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF10">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11 16" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 11 16" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 11 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="19">
        <location>
            <begin position="173"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="18">
        <location>
            <begin position="332"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="17">
        <location>
            <begin position="635"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="17">
        <location>
            <begin position="702"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="792"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="221"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABO95635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="830" mass="91461" checksum="E8FC76F53EB79529" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWT8</accession>
    <name>A4RWT8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_37092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417390.1">
        <property type="nucleotide sequence ID" value="XM_001417353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWT8"/>
    <dbReference type="GeneID" id="5001587"/>
    <dbReference type="Gramene" id="ABO95683">
        <property type="protein sequence ID" value="ABO95683"/>
        <property type="gene ID" value="OSTLU_37092"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37092"/>
    <dbReference type="eggNOG" id="ENOG502QU5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042215_1_0_1"/>
    <dbReference type="OMA" id="FFPEHEE"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF2">
        <property type="entry name" value="LYSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="389" mass="43092" checksum="5A07CAA9421BD0F2" modified="2007-05-15" version="1">MAAASAAALRATGANAADDDARRLFEQRFPVLFKPFIGRGTRATVKRTIVPGQMWAFEQNIELGPLETTIRCVTCKLSDGSLWVHAPLAPTEEFFEFVESCGDGTSACVRYVVVPTYALEHKIFAKDALARWRGAKLYASPGQFTFPIRDVSDEIVFGKKVDFVLQGSDLDVRSPVAVPWKDEIEFETLEAGTFDVGSTKQTIYETAFFHKPSKTLIVTDALAQIPIDPPEANSVEKLLVVSQRSTADPVPEDTPEARRAGWEKTALLVSYFFPEHEELDPAAPGTVIWTDGWHDNFQALAGRLLVPPVVRTLLYAQNPNAVRRWVAAVSSRWDFERVVPAHWEAPLACSPGDFKRAFAFLDDDAIDAFPEGDLKRGLQPVADIVLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWT9</accession>
    <name>A4RWT9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417634.1">
        <property type="nucleotide sequence ID" value="XM_001417597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWT9"/>
    <dbReference type="GeneID" id="5001456"/>
    <dbReference type="Gramene" id="ABO95927">
        <property type="protein sequence ID" value="ABO95927"/>
        <property type="gene ID" value="OSTLU_31454"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31454"/>
    <dbReference type="HOGENOM" id="CLU_2417233_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="92" mass="10331" checksum="4F18B9F6C9B59F46" modified="2007-05-15" version="1">MVDLHRAHTIHEDYARNHKLFKLPRTSLGALCVASGVGVATYYAFRSFVTSTQSNASTGTTGMTKHEEVWRSSWDKGSPRKHVNNLWNDPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWZ3</accession>
    <name>A4RWZ3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Signal peptidase complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_92692</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the SPCS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417907.1">
        <property type="nucleotide sequence ID" value="XM_001417870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWZ3"/>
    <dbReference type="GeneID" id="5001758"/>
    <dbReference type="Gramene" id="ABO96200">
        <property type="protein sequence ID" value="ABO96200"/>
        <property type="gene ID" value="OSTLU_92692"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92692"/>
    <dbReference type="eggNOG" id="ENOG502QVCN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1350858_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009582">
        <property type="entry name" value="Spc2/SPCS2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06703">
        <property type="entry name" value="SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="203" mass="21899" checksum="69D555CA0363F3FE" modified="2007-05-15" version="1">MATPISNVYDHVAVRRAYDDATVCAVLDAGYDEDTRTVDAKIALSIAAIGAACAAHAVTMTNDATRWACAAAYGALACGAPCVAKYAERDALLLTRARGVDCDGREPAAWARNERSKDGLTVHVRCARLAETLEVIVSAKSDGKCEAKDAVRCDVRCEEFVTEDGEFLEDEYEALIWRVLEAFERGKGRGASVDCRAAIEKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXQ6</accession>
    <name>A4RXQ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SDG3509</name>
        <name evidence="3" type="ORF">OSTLU_15488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417799.1">
        <property type="nucleotide sequence ID" value="XM_001417762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXQ6"/>
    <dbReference type="GeneID" id="5001892"/>
    <dbReference type="Gramene" id="ABO96092">
        <property type="protein sequence ID" value="ABO96092"/>
        <property type="gene ID" value="OSTLU_15488"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15488"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038635_0_0_1"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF145">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="43"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="490" mass="54389" checksum="C183DFA443D4C6C7" modified="2007-05-15" version="1">MTSKPASSKSAGKRAAEARGRDAGGGGGGAFAKWLRDNKVELDGVEVARFARTGRGVRATRDLRVGEVVVSVPDDAVLTVDACAVKKELGEFVGDGDDEAPSPRLDKELLVIAVMCEMCAGKSSAWCEYLETVHEAVRVGHSVLAWDDEQVTALFGTDAWRDAYENDDETLDLPMMTEEHFENVVTLFFKLFPKLASGLSVEALRELHFAATAMVAGYSFTLGDDEIQAMVPFWDMLNHAPPCEASVRLHHDQKNGCLQMITVRGVKKGEEVFNTYGPLRNAELLRRYGFVLPRNPHGGTTVGLAEVIQAAMGANPLVVDELPLRLAWLESRGLADEELSTRFFVHRTGRPSDKLLIAMRLLTLKPEEMTALIEADFDDEEQLMLLEGNDEERTEQSYMVGASLQFLGMYAKSRYAESMKASRLTYKMYASVSPHVQKHESIYRAWAAAVVRMDEQRALTKLGRWTYHPGRSEDALLHAWPFPVADEEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXZ3</accession>
    <name>A4RXZ3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_31868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417839.1">
        <property type="nucleotide sequence ID" value="XM_001417802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXZ3"/>
    <dbReference type="STRING" id="436017.A4RXZ3"/>
    <dbReference type="GeneID" id="5001994"/>
    <dbReference type="Gramene" id="ABO96132">
        <property type="protein sequence ID" value="ABO96132"/>
        <property type="gene ID" value="OSTLU_31868"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31868"/>
    <dbReference type="eggNOG" id="ENOG502QT7P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025174_3_1_1"/>
    <dbReference type="OMA" id="YNLQWSF"/>
    <dbReference type="OrthoDB" id="9930022at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="entry name" value="HI0933 insert domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="BaiN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055178">
        <property type="entry name" value="RsdA/BaiN/AoA(So)-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057661">
        <property type="entry name" value="RsdA/BaiN/AoA(So)_Rossmann"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00275">
        <property type="entry name" value="aminoacetone oxidase family FAD-binding enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="OS12G0638800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887:SF2">
        <property type="entry name" value="OS12G0638800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03486">
        <property type="entry name" value="HI0933_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22780">
        <property type="entry name" value="HI0933_like_1st"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160996">
        <property type="entry name" value="HI0933 insert domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RsdA/BaiN/AoA(So)-like Rossmann fold-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="RsdA/BaiN/AoA(So)-like insert" evidence="5">
        <location>
            <begin position="153"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="RsdA/BaiN/AoA(So)-like insert" evidence="5">
        <location>
            <begin position="257"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="401" mass="42839" checksum="4954B11B51C331B6" modified="2007-05-15" version="1">MSGGARCNVLPTSATANDFTTESANRRLKAVLASWSVERCREWLETEIGLGLGIEIASNKYFPLSNSSREVRDRLVAACEKAGVEFKYETSVDGVVRGSDGMGWTLRVRGSGDERARAIVLAMGGLSFPAVGTDGTGYAIARRDLGHALHEPYPALVPLTGPHPGGEPLPGVSVEVELKVAAANADGGGGKKKAQAIRKGFLFTHRGYSGPSVLDLSHHLVRPLVRANESKGGSLRDEDFDAPTSSSPRMVINWSGIKREEWQERLTAPPGRALVVSRLREALPSRLADALVAESGVDSRCKIAELKKDDRAKLLRVLTEYEIAVKGHQGYRKAEVTGGGVALDELDTASMASLKAPGIYMCGEVCDVFGRIGGFNFLWAWCSGRLAGMSAAKAISSADDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY49</accession>
    <name>A4RY49_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_45840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418107.1">
        <property type="nucleotide sequence ID" value="XM_001418070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY49"/>
    <dbReference type="STRING" id="436017.A4RY49"/>
    <dbReference type="GeneID" id="5002027"/>
    <dbReference type="Gramene" id="ABO96400">
        <property type="protein sequence ID" value="ABO96400"/>
        <property type="gene ID" value="OSTLU_45840"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45840"/>
    <dbReference type="eggNOG" id="KOG1197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_1"/>
    <dbReference type="OMA" id="KGMTAHY"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="36"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="364" mass="39232" checksum="CE90C1248C72B326" modified="2007-05-15" version="1">MLARSARSLRKTLTGVRAFASGVPDVMTAAVIRETGPASNMKIEKDYPTPKLTAGGVIVKNKYSGINFIDTYHRSGLYKRELPFIGGQEGGGYIAAASDEAIAQGVKVGDRVSYSSVFQTYAQYTAVPASKVITVPESIPLDVAVSCGVQGMTAHYLTHSAHAGLVKPGEWMLIHGTGSGTCQWAAQMAKLRGYKVIGTCSKSKEDIARATGVDELIVYDEAPGTSYEDYTSVDLVPRVMEITKGEGVKAVIDGIGLATYETSIDVLARRGIFVSFGNASGAVPAFPPLRFINKSGYLTRPKLNDYTVTREELMERANDIFGWISSGELQVAVDRCFPLEQCVEGHNYLEAGKSRGKVLYEISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY80</accession>
    <name>A4RY80_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_38392</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418123.1">
        <property type="nucleotide sequence ID" value="XM_001418086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY80"/>
    <dbReference type="STRING" id="436017.A4RY80"/>
    <dbReference type="GeneID" id="5001949"/>
    <dbReference type="Gramene" id="ABO96416">
        <property type="protein sequence ID" value="ABO96416"/>
        <property type="gene ID" value="OSTLU_38392"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38392"/>
    <dbReference type="eggNOG" id="KOG0417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_3_1"/>
    <dbReference type="OMA" id="IVFRTRI"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23793">
        <property type="entry name" value="UBCc_UBE2E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000003">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 E3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="10"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="159" mass="17667" checksum="78E7E6480819D6BF" modified="2007-05-15" version="1">MSDKKSSLSSSSRRIQKELAEISLEPPTNCSAGPKGDNLYEWVSTIVGPSGSPYNGGVFFLDIQFPTDYPFKPPKVTFRTRIYHCNVNSSGQICLDILKEQWSPALTISKVLLSICSLLTDANPHDPLVGSIAQQFLQDKENHDKTAQEWTKVRSAEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYJ6</accession>
    <name>A4RYJ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">IMP-specific 5'-nucleotidase 1</fullName>
            <ecNumber evidence="4">3.1.3.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_4044</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>IMP + H2O = inosine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27718"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="3.1.3.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISN1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.99" evidence="4"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418174.1">
        <property type="nucleotide sequence ID" value="XM_001418137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYJ6"/>
    <dbReference type="STRING" id="436017.A4RYJ6"/>
    <dbReference type="GeneID" id="5002361"/>
    <dbReference type="Gramene" id="ABO96467">
        <property type="protein sequence ID" value="ABO96467"/>
        <property type="gene ID" value="OSTLU_4044"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4044"/>
    <dbReference type="eggNOG" id="ENOG502QR24">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031816_0_0_1"/>
    <dbReference type="OMA" id="WGVLACQ"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006190">
        <property type="term" value="P:inosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071590">
        <property type="term" value="P:nicotinamide riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071592">
        <property type="term" value="P:nicotinic acid riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009453">
        <property type="entry name" value="ISN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213:SF1">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06437">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO96467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="329" mass="37533" checksum="4ED3E5D86E4335BD" modified="2007-05-15" version="1" fragment="single">EVFTKVETWIDEVLELPKEKRRFSKLSRMVPAVGFFFHRLPLLKALREYDEFSSLSKRRYVLPNFAEVRHILNIAQVHASSKDVRLVTFDADGTLYADGEHFEDDNKMIDKIMQLMELGIHVAIVTAAGYPGEPTKFEGRLKGLVDAFEAQALPKEVYEKFHVMGGECNYLLRVNDEYRLEFVPSEEWHSEHMYDWRDNDDVRMFLDRAEEFLTSYAKHLGVQVDVLRKEYAVGVLPKGDTIYENLEEMALASQAELSDAKIPFCAFNGGNDVFVDVGNKHIGLQALMKYLNVAGSQTLHVGDRFTLTGNDAKVREAASILWVASPDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYM5</accession>
    <name>A4RYM5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418191.1">
        <property type="nucleotide sequence ID" value="XM_001418154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYM5"/>
    <dbReference type="STRING" id="436017.A4RYM5"/>
    <dbReference type="GeneID" id="5002579"/>
    <dbReference type="Gramene" id="ABO96484">
        <property type="protein sequence ID" value="ABO96484"/>
        <property type="gene ID" value="OSTLU_15712"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15712"/>
    <dbReference type="eggNOG" id="KOG3048">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091867_0_1_1"/>
    <dbReference type="OMA" id="QAKFKAC"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071370">
        <property type="term" value="P:cellular response to gibberellin stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009631">
        <property type="term" value="P:cold acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043622">
        <property type="term" value="P:cortical microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901703">
        <property type="term" value="P:protein localization involved in auxin polar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990113">
        <property type="term" value="P:RNA polymerase I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990114">
        <property type="term" value="P:RNA polymerase II core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990115">
        <property type="term" value="P:RNA polymerase III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23157">
        <property type="entry name" value="Prefoldin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674:SF2">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13519" checksum="EC3D7770D1E4428A" modified="2007-05-15" version="1" fragment="single">MTSLDLRTATLEQLKVADEQLREEVTSYSESLQMLSKAVSRYHSSGSAIEELSKETVGKDMLVPLTESLYVPGKIAAVDKVLLDVGTGYFIEHDTEKGIDYCKRKVNFIRDNMEKLMELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYM6</accession>
    <name>A4RYM6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA-binding S4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_12600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TlyA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418417.1">
        <property type="nucleotide sequence ID" value="XM_001418380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYM6"/>
    <dbReference type="STRING" id="436017.A4RYM6"/>
    <dbReference type="GeneID" id="5002580"/>
    <dbReference type="Gramene" id="ABO96710">
        <property type="protein sequence ID" value="ABO96710"/>
        <property type="gene ID" value="OSTLU_12600"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12600"/>
    <dbReference type="eggNOG" id="ENOG502QRA0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058015_0_0_1"/>
    <dbReference type="OMA" id="VLMVKPQ"/>
    <dbReference type="OrthoDB" id="449109at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004538">
        <property type="entry name" value="Hemolysin_A/TlyA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047048">
        <property type="entry name" value="TlyA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00478">
        <property type="entry name" value="tly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319">
        <property type="entry name" value="BACTERIAL HEMOLYSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319:SF0">
        <property type="entry name" value="BACTERIAL HEMOLYSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005578">
        <property type="entry name" value="TlyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="4">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="5">
        <location>
            <begin position="43"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="26636" checksum="D1CAB7937135D155" modified="2007-05-15" version="1">MNSPSRSWIAQGKVLVDGQPVTKAGTKLKPSVKIEVIAEQPKFVCRAGLKLEKALAHFGVDVSGCTALDSGLSTGGFTDCLLQSGAKKVYGVDVGYGQVAEKIRQDERVIIMERTNLRYVTDLPDIVDVVTLDLSFISVLKVLPAICRILKPGGTMLVLIKPQFEAKRSQIGSKGVVRDANVHKEVIENVIQGAKLYGFEYIDHTTSPIKGAKEGNTEFLAHFTMSLDGPPPEILQNTVEVEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYS0</accession>
    <name>A4RYS0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_49732</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418212.1">
        <property type="nucleotide sequence ID" value="XM_001418175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYS0"/>
    <dbReference type="STRING" id="436017.A4RYS0"/>
    <dbReference type="GeneID" id="5002306"/>
    <dbReference type="Gramene" id="ABO96505">
        <property type="protein sequence ID" value="ABO96505"/>
        <property type="gene ID" value="OSTLU_49732"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49732"/>
    <dbReference type="eggNOG" id="KOG0326">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_30_0_1"/>
    <dbReference type="OMA" id="TYEDRHT"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019060">
        <property type="term" value="P:intracellular transport of viral protein in host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016032">
        <property type="term" value="P:viral process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd17940">
        <property type="entry name" value="DEADc_DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000114">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000364">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="16">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="76"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="256"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO96505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="419" mass="47587" checksum="74F11B62725397F7" modified="2007-05-15" version="1">MGWNERTRRAPPPQPQQNGNWKDTLALPPRDERYRTEDVTATKGNEFEDYFLKRELLMGIFEKGFERPSPIQEESIPIALTGRDILARAKNGTGKTAAFTIPILEKVDTSKNIIQAVILVPTRELALQTSQVAKELGKHLGVAVMVTTGGTSLKDDIMRLHQPVHIVVATPGRLVDLASKSVAKLGQATMLAMDEADKLLSPEFQPVIAQVINFMAKNRQILLYSATFPVTVKDFKDKYLRKPYVINLMEELTLKGITQYYAFVEEKQKVHCLNTLFSKLQINQSIIFCNSVTRVELLARKITELGYSCFYIHAKMIQAHRNRVFHDFRNGACRNLVSSDLFTRGIDIQSVNVVINFDFPKNSETYLHRVGRSGRFGHLGIAVNLITYDDRMNLFRIEQELGTEIQQIPSQIDPSKYCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZC1</accession>
    <name>A4RZC1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Threonine synthase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418305.1">
        <property type="nucleotide sequence ID" value="XM_001418268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZC1"/>
    <dbReference type="STRING" id="436017.A4RZC1"/>
    <dbReference type="GeneID" id="5002515"/>
    <dbReference type="Gramene" id="ABO96598">
        <property type="protein sequence ID" value="ABO96598"/>
        <property type="gene ID" value="OSTLU_32331"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32331"/>
    <dbReference type="eggNOG" id="KOG2616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_437078_0_0_1"/>
    <dbReference type="OMA" id="NFERYLY"/>
    <dbReference type="OrthoDB" id="5203861at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046360">
        <property type="term" value="P:2-oxobutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009071">
        <property type="term" value="P:serine family amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="entry name" value="Threonine synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051166">
        <property type="entry name" value="Threonine_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690">
        <property type="entry name" value="THREONINE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690:SF1">
        <property type="entry name" value="THREONINE SYNTHASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24857">
        <property type="entry name" value="THR4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Threonine synthase N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="626" mass="68586" checksum="EFDCB3C098CBCB22" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZK2</accession>
    <name>A4RZK2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_35457</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Voltage-dependent rectifying anion channel that facilitates the translocation between chloroplast and cytoplasm of phosphorylated carbohydrates such as triosephosphate, 3-phosphoglycerate and inorganic phosphate (Pi) depending of ATP to triosephosphate ratio in the plastidial intermembrane space; in high triosephosphate/ATP conditions (e.g. photosynthesis), export of triosphosphate from chloroplast (outward rectifying channels), but in high ATP/triosephosphate conditions (e.g. dark phase), import of phosphosolutes (inward rectifying channels).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Etioplast membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the plastid outer envelope porin OEP21 (TC 1.B.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418587.1">
        <property type="nucleotide sequence ID" value="XM_001418550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZK2"/>
    <dbReference type="STRING" id="436017.A4RZK2"/>
    <dbReference type="GeneID" id="5003069"/>
    <dbReference type="Gramene" id="ABO96880">
        <property type="protein sequence ID" value="ABO96880"/>
        <property type="gene ID" value="OSTLU_35457"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35457"/>
    <dbReference type="eggNOG" id="ENOG502RX9S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104399_0_0_1"/>
    <dbReference type="OMA" id="DWNIWKF"/>
    <dbReference type="OrthoDB" id="503907at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009707">
        <property type="term" value="C:chloroplast outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034426">
        <property type="term" value="C:etioplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044070">
        <property type="term" value="P:regulation of monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034575">
        <property type="entry name" value="OEP21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35993">
        <property type="entry name" value="OUTER ENVELOPE PORE PROTEIN 21B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35993:SF1">
        <property type="entry name" value="OUTER ENVELOPE PORE PROTEIN 21B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="176" mass="20138" checksum="31D0BE0EBE6245BB" modified="2007-05-15" version="1">METSLRYDTTSRSLSLFAKERFTNSEDVVLTVSGSLDTRDGRMDGKAHVRKRLFSPAKSSPLVPDRADIGLTYETKLDDVRYGARARKTVDVSPSKDGMSTVTLRGGVSYGVKRSKPLIEGTIELTHKVFNFQEDQDLRLRVGYDLVKREPYAHIRENNWSFKTDFQKSWSVYYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZN5</accession>
    <name>A4RZN5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_87679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418828.1">
        <property type="nucleotide sequence ID" value="XM_001418791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZN5"/>
    <dbReference type="GeneID" id="5002621"/>
    <dbReference type="Gramene" id="ABO97121">
        <property type="protein sequence ID" value="ABO97121"/>
        <property type="gene ID" value="OSTLU_87679"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87679"/>
    <dbReference type="eggNOG" id="ENOG502S4AI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_626064_0_0_1"/>
    <dbReference type="OMA" id="QSERNYR"/>
    <dbReference type="OrthoDB" id="510159at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF7">
        <property type="entry name" value="TRAB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="436" mass="47088" checksum="B513A3DCA843459B" modified="2007-05-15" version="1">MRASIARASTMRANASSNARRPTRARIARSTASRARPARVARAPRAFFEDQEDDFDLSPSTTATATPDAWTTGTFTPLDERCVAFGVSHLVEGAHDAAEYILRRGPKVVVVETAVTSEHGDATGNAVNYEQGVTAMMVDAATAPEALVFVTRLAGALKGELGPIADSPQWENMKAQLPPEVLVYAAAFAVGATVIYGDRPKAVTYKRLMATPTLEELDGTFAAQSERNYRLLLPEDHPLAAKANERVDDCFERIIIDERDRVMASTIKECAEKTDDGTVVAVIGVDHIAGVSRIYRDNFAAAENDAKIAELNAAPEGAPDSMGVRVALAQRLMGLRCPPALVDDVMRTLSWDVQNLSAADANEFELVSEVYGSPRMLMACVEDKELLDAVIGGFKCDYSEEVLAPVRAVRPINGGKGYSDEIVNALRTSSYVNFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZR2</accession>
    <name>A4RZR2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_92980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418841.1">
        <property type="nucleotide sequence ID" value="XM_001418804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZR2"/>
    <dbReference type="STRING" id="436017.A4RZR2"/>
    <dbReference type="GeneID" id="5003043"/>
    <dbReference type="Gramene" id="ABO97134">
        <property type="protein sequence ID" value="ABO97134"/>
        <property type="gene ID" value="OSTLU_92980"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92980"/>
    <dbReference type="HOGENOM" id="CLU_572870_0_0_1"/>
    <dbReference type="OMA" id="LGWRFDS"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="68"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="326"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="396"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="481" mass="54011" checksum="CDCD176F22B7CD70" modified="2007-05-15" version="1">MSIEERKQKPTKLLEDELGRPLHALQDDSLAAAEETFRRDVFASFESGRKLLGSHRVEDYLDEYYGESDRTPPLMLADTLSMSECIEFMRAFNVSSAPVLTGDAKTFIGWCSVFDILRDVAAAIQRAKPPGREIVRETAALTGQPHVHSAWGVLRHAFRTVTSAERLSGESVERREVELDNHRREWLSSISPEDVKNAIDEVLNMTLKEARRKTHSEEDGRMVSRVAAADADLLELVRSGFLRHIVTAGDFIAPRQAHVCHRVCTYSLKPDDKDEMKEKMVVEALVSQADIVQFLYDNSDSFDDALKRRNLTSLGLGARKSHRVFPDSDVMCVFPETRLLDAFVMMHVTGHSCLGVVDEPRGKLIDVLSVSDIREAVFDVDALCDTVERYLKSRALTRIPLVTLTEDADFIDVLGALAKNSIHHVFVVDLEGSPLRVVTPTDVLTRLALPSARKLGWRFDSYEVHPDTFENNPATMIRPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZS8</accession>
    <name>A4RZS8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418622.1">
        <property type="nucleotide sequence ID" value="XM_001418585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZS8"/>
    <dbReference type="GeneID" id="5003053"/>
    <dbReference type="Gramene" id="ABO96915">
        <property type="protein sequence ID" value="ABO96915"/>
        <property type="gene ID" value="OSTLU_92987"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92987"/>
    <dbReference type="HOGENOM" id="CLU_465717_0_0_1"/>
    <dbReference type="OMA" id="IMHAWGV"/>
    <dbReference type="OrthoDB" id="548986at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="586" mass="62916" checksum="0242365A1615F91E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S040</accession>
    <name>A4S040_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribulose bisphosphate carboxylase large chain</fullName>
            <ecNumber evidence="3">4.1.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">rbcL</name>
        <name evidence="18" type="ORF">OSTLU_32608</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 (2R)-3-phosphoglycerate + 2 H(+) = D-ribulose 1,5-bisphosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="4.1.1.39"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>D-ribulose 1,5-bisphosphate + O2 = 2-phosphoglycolate + (2R)-3-phosphoglycerate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:36631"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58033"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterohexadecamer of 8 large chains and 8 small chains; disulfide-linked. The disulfide link is formed within the large subunit homodimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RuBisCO large chain family. Type I subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.39" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418678.1">
        <property type="nucleotide sequence ID" value="XM_001418641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S040"/>
    <dbReference type="STRING" id="436017.A4S040"/>
    <dbReference type="GeneID" id="5002752"/>
    <dbReference type="Gramene" id="ABO96971">
        <property type="protein sequence ID" value="ABO96971"/>
        <property type="gene ID" value="OSTLU_32608"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32608"/>
    <dbReference type="HOGENOM" id="CLU_386556_0_0_1"/>
    <dbReference type="OMA" id="DMFACSP"/>
    <dbReference type="OrthoDB" id="496601at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016984">
        <property type="term" value="F:ribulose-bisphosphate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009853">
        <property type="term" value="P:photorespiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08210">
        <property type="entry name" value="RLP_RrRLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.110">
        <property type="entry name" value="Ribulose bisphosphate carboxylase, large subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.150">
        <property type="entry name" value="RuBisCO large subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033966">
        <property type="entry name" value="RuBisCO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000685">
        <property type="entry name" value="RuBisCO_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036376">
        <property type="entry name" value="RuBisCO_lsu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036422">
        <property type="entry name" value="RuBisCO_lsu_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42704">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42704:SF17">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00016">
        <property type="entry name" value="RuBisCO_large"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00158">
        <property type="entry name" value="5-methylthio-D-ribulose_1-phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00014">
        <property type="entry name" value="RuBisCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00301">
        <property type="entry name" value="RuBisCO-like_proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51649">
        <property type="entry name" value="RuBisCo, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54966">
        <property type="entry name" value="RuBisCO, large subunit, small (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="11" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0601">Photorespiration</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribulose bisphosphate carboxylase large subunit C-terminal" evidence="17">
        <location>
            <begin position="402"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO96971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="679" mass="72417" checksum="E5BF8B2ECFDCC15D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0C4</accession>
    <name>A4S0C4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32691</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418720.1">
        <property type="nucleotide sequence ID" value="XM_001418683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0C4"/>
    <dbReference type="STRING" id="436017.A4S0C4"/>
    <dbReference type="GeneID" id="5002929"/>
    <dbReference type="Gramene" id="ABO97013">
        <property type="protein sequence ID" value="ABO97013"/>
        <property type="gene ID" value="OSTLU_32691"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32691"/>
    <dbReference type="eggNOG" id="KOG2669">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_772420_0_0_1"/>
    <dbReference type="OMA" id="EECESSA"/>
    <dbReference type="OrthoDB" id="10069473at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16981">
        <property type="entry name" value="CID_RPRD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF0">
        <property type="entry name" value="CID DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="3">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="341" mass="36867" checksum="556ED33B8E043A01" modified="2007-05-15" version="1">MTDAPSAFTTKLASLNGSAQSIETLSHWCIFHRKNARTLAGTWDERLRAAASKQKLPFLYLASDIVQKSRKKGPEWADALVGYMPDACKHAVEHGDGTTTEKVKKLLRVWGERQCFPGASTESWLDGASDGGGGSTAVAAKVAAPAATSAAPVAKKNKNDLAEVPALSGDNAALAKLLVKMENAERDVAAASERFDADVREELLDETNVENAEDPVGMLRAVQCCESAIVFKRNAVDTMTETLDTLEKKLRAALARVEAARESQSGVNMGELTQMMIKALKARKKASKRNADFIVRQIASEAGDAPLPEPVDFDADADNYDPSDAPDEYHPPDESNKRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0N2</accession>
    <name>A4S0N2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_8830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418770.1">
        <property type="nucleotide sequence ID" value="XM_001418733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0N2"/>
    <dbReference type="STRING" id="436017.A4S0N2"/>
    <dbReference type="GeneID" id="5002795"/>
    <dbReference type="Gramene" id="ABO97063">
        <property type="protein sequence ID" value="ABO97063"/>
        <property type="gene ID" value="OSTLU_8830"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8830"/>
    <dbReference type="eggNOG" id="KOG0126">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045495_5_2_1"/>
    <dbReference type="OMA" id="CAPKPQI"/>
    <dbReference type="OrthoDB" id="2573941at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12411">
        <property type="entry name" value="RRM_ist3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045844">
        <property type="entry name" value="RRM_Ist3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="122" mass="13629" checksum="0C22B95030D41F51" modified="2007-05-15" version="1" fragment="single">MNALTQIKNTQKATMREIESGMGEEASWHARYKHSAYVYAGGLAFNMTEGDILAVFSQFGEVVDVNLVRDEEKGRSRGFAFICYADQRSTVLAVDNLNGATVVGRTIKVDHVDDYKMKNEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0P3</accession>
    <name>A4S0P3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ketopantoate reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419014.1">
        <property type="nucleotide sequence ID" value="XM_001418977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0P3"/>
    <dbReference type="STRING" id="436017.A4S0P3"/>
    <dbReference type="GeneID" id="5002802"/>
    <dbReference type="Gramene" id="ABO97307">
        <property type="protein sequence ID" value="ABO97307"/>
        <property type="gene ID" value="OSTLU_32816"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32816"/>
    <dbReference type="eggNOG" id="ENOG502QRWE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069934_0_0_1"/>
    <dbReference type="OMA" id="YSRAVSH"/>
    <dbReference type="OrthoDB" id="38730at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044:SF1">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="28699" checksum="8451A82BE34E1F74" modified="2007-05-15" version="1">MTNATKGEVMPSIIIGGGRVGQALRDMGVEGDVVVRRGEAFPSEPKTGPIYVATRNDVLEDVIKNCPADRREDLVFMQNGMLQQFLDAQGLGANTQALIYFAVAALGDKPTDGVTELNPEGLTAATGKWADAVAARFHNGDLSCHVLDAPTYEGSMYEKLIWICAMMLVGAQHEGAKVGDVATTYKDEVVALIEELLSGTTACTGAKFAPGAVDRLIAYAKTVAHFPCGVKEFPWRNGYFYGLSEKAIADGKSDPFPTHTALLKNIGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0S4</accession>
    <name>A4S0S4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rubredoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_9570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419028.1">
        <property type="nucleotide sequence ID" value="XM_001418991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0S4"/>
    <dbReference type="STRING" id="436017.A4S0S4"/>
    <dbReference type="GeneID" id="5002710"/>
    <dbReference type="Gramene" id="ABO97321">
        <property type="protein sequence ID" value="ABO97321"/>
        <property type="gene ID" value="OSTLU_9570"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9570"/>
    <dbReference type="eggNOG" id="ENOG502S3MR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083159_2_1_1"/>
    <dbReference type="OrthoDB" id="6379857at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043448">
        <property type="term" value="P:alkane catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050526">
        <property type="entry name" value="Rubredoxin_ET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47627">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47627:SF1">
        <property type="entry name" value="RUBREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="93" mass="10421" checksum="304332949032076F" modified="2007-05-15" version="1" fragment="single">WQCQSCMYEYKPKVGDDFYPVSAGTQFKDLPDDWRCPTCGAEKVKFKSLGKQVAGFEQNQGYGLGTNAMTEGEKSQLIYGALAFFFLCFIAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0T8</accession>
    <name>A4S0T8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">E1 ubiquitin-activating enzyme</fullName>
            <ecNumber evidence="4">6.2.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_35452</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.45" evidence="4"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418796.1">
        <property type="nucleotide sequence ID" value="XM_001418759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0T8"/>
    <dbReference type="STRING" id="436017.A4S0T8"/>
    <dbReference type="GeneID" id="5002695"/>
    <dbReference type="Gramene" id="ABO97089">
        <property type="protein sequence ID" value="ABO97089"/>
        <property type="gene ID" value="OSTLU_35452"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35452"/>
    <dbReference type="eggNOG" id="KOG2012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002556_0_0_1"/>
    <dbReference type="OMA" id="CIREKCN"/>
    <dbReference type="OrthoDB" id="10252231at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01490">
        <property type="entry name" value="Ube1_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000015">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2660:FF:000002">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.180:FF:000002">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.60:FF:000001">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.180">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, FCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12550">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032420">
        <property type="entry name" value="E1_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032418">
        <property type="entry name" value="E1_FCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042302">
        <property type="entry name" value="E1_FCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018075">
        <property type="entry name" value="UBQ-activ_enz_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01408">
        <property type="entry name" value="Ube1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF4">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16191">
        <property type="entry name" value="E1_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16190">
        <property type="entry name" value="E1_FCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09358">
        <property type="entry name" value="E1_UFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="11">
        <location>
            <begin position="882"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1009" mass="109982" checksum="1843E997330AD63D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0U2</accession>
    <name>A4S0U2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_10269</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419037.1">
        <property type="nucleotide sequence ID" value="XM_001419000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0U2"/>
    <dbReference type="STRING" id="436017.A4S0U2"/>
    <dbReference type="GeneID" id="5002736"/>
    <dbReference type="Gramene" id="ABO97330">
        <property type="protein sequence ID" value="ABO97330"/>
        <property type="gene ID" value="OSTLU_10269"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10269"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039068_0_1_1"/>
    <dbReference type="OMA" id="WRHSIWA"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="78"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="6">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="6">
        <location>
            <begin position="143"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="6">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="295" mass="33475" checksum="C34D0FC22E861B46" modified="2007-05-15" version="1" fragment="single">NTVGAEYDAWTEEEILEYYWGEHIHLGYYKDEDLKRGAGTLFGHRVKDFIEAKEDFVDEMYAWSKAEANNGGAKPRKILDVGCGIGGATRRLASKCAGATAEVTGITLSTKQAARATALAAAQNIPNAKFEVMDALAMEFDDDTFDMVWACESGEHMPDKKKYVEEMVRVLKPGGTLVIATWCQRHTPPALTKEEKSKLQFLYDEWAHPYFISIQDYCELAEGTGAMKNVDGDDWTKQTIVSWRHSIWAGVYDPLPVFTRPKIWYKTLRDIICLERMRRAFGEELMQYGMIRGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0U3</accession>
    <name>A4S0U3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Rotamase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_32866</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418800.1">
        <property type="nucleotide sequence ID" value="XM_001418763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0U3"/>
    <dbReference type="STRING" id="436017.A4S0U3"/>
    <dbReference type="GeneID" id="5002696"/>
    <dbReference type="Gramene" id="ABO97093">
        <property type="protein sequence ID" value="ABO97093"/>
        <property type="gene ID" value="OSTLU_32866"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32866"/>
    <dbReference type="HOGENOM" id="CLU_098197_2_1_1"/>
    <dbReference type="OMA" id="AKFVMGD"/>
    <dbReference type="OrthoDB" id="497812at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048261">
        <property type="entry name" value="SlpA/SlyD-like_ins_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47861">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47861:SF3">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="2"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="152" mass="16212" checksum="561695A4EA09A83E" modified="2007-05-15" version="1">MTLNDGTVIDDTRSDARQGQPVTITLGDDSLFARIGEELATMTPGDVRENVTLAAKDAFGERDDAKVQRFPLSPEEAQSMASQVQVGQLVQLPDGARALCLGLDGESVTLDLNHPLAGQDLCFELELVSIAEGLNIFGTPMVSFTPPQPASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S111</accession>
    <name>A4S111_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase</fullName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_297</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419281.1">
        <property type="nucleotide sequence ID" value="XM_001419244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S111"/>
    <dbReference type="STRING" id="436017.A4S111"/>
    <dbReference type="GeneID" id="5003311"/>
    <dbReference type="Gramene" id="ABO97574">
        <property type="protein sequence ID" value="ABO97574"/>
        <property type="gene ID" value="OSTLU_297"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_297"/>
    <dbReference type="eggNOG" id="KOG0970">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001718_0_0_1"/>
    <dbReference type="OMA" id="RTAQNHE"/>
    <dbReference type="OrthoDB" id="6755010at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="entry name" value="DNA_polB_alpha_exo"/>
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        <property type="entry name" value="POLBc_alpha"/>
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        <property type="entry name" value="DNA polymerase"/>
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        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
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        <property type="entry name" value="Helix hairpin bin"/>
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        <property type="entry name" value="Palm domain of DNA polymerase"/>
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        <property type="entry name" value="RNaseH-like_sf"/>
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        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
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    </dbReference>
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        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
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        <property type="entry name" value="DNA_pol_B"/>
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        <property type="entry name" value="DNA_pol_B_exo1"/>
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        <property type="entry name" value="DNAPOLB"/>
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        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Ribonuclease H-like"/>
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        <property type="entry name" value="DNA_POLYMERASE_B"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="154"/>
            <end position="413"/>
        </location>
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    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="14">
        <location>
            <begin position="478"/>
            <end position="936"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="516"/>
            <end position="538"/>
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    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="990"/>
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    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO97574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="990" mass="110167" checksum="4FE322F44FB7CE63" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S170</accession>
    <name>A4S170_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_42318</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="8">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO97605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419312.1">
        <property type="nucleotide sequence ID" value="XM_001419275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S170"/>
    <dbReference type="STRING" id="436017.A4S170"/>
    <dbReference type="GeneID" id="5003264"/>
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        <property type="protein sequence ID" value="ABO97605"/>
        <property type="gene ID" value="OSTLU_42318"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42318"/>
    <dbReference type="eggNOG" id="KOG0343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_5_1"/>
    <dbReference type="OMA" id="HCLTMCL"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17941">
        <property type="entry name" value="DEADc_DDX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="33"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="220"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="446"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="481" mass="53848" checksum="6A1E597462AFB5E6" modified="2007-05-15" version="1" fragment="single">MRKFAHLPISQATKAALRECKFKEMTAIQRATLPHALCGRDVLGAAKTGSGKTLAYVVPLIESLWRKKWGRQDGVGALVISPTRELAIQIFQCLTKVGARHTMSAGLLIGGKDVQEEANRVNKMNILVCTPGRLLQHMDETPMFDCVTLQMLVLDEADRMLDLGFTKTLNAIIDNLPKNRQTLLFSATQTKSVKDLARLGLKDPEYLSVHAESVHSTPPKLQQMVTTCALEKKIEVLWSFIKTHLNAKTLVFFSSCKQVKFVYEIFKRMRPGVPLQCIHGRLKQARRQGVFYNFCNAKETVLFATDVASRGLDFPSVDWVVQADCPEDVATYIHRVGRTARYTAAGKGLLMLTPGESHFMKELEVAKVPLKPIKLNPKKQSSRIQSSMQGLLSKDSDLKYLSQRAVICYLRSVYLQKNKKVFDIKSIDMDAYAFSMGLPNAPRLRFLQQGKSAGARDESDSDDDDEAEDDASDREEDEASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1H7</accession>
    <name>A4S1H7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ZIP family transporter: zinc ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_12811</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419149.1">
        <property type="nucleotide sequence ID" value="XM_001419112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1H7"/>
    <dbReference type="STRING" id="436017.A4S1H7"/>
    <dbReference type="GeneID" id="5003475"/>
    <dbReference type="Gramene" id="ABO97442">
        <property type="protein sequence ID" value="ABO97442"/>
        <property type="gene ID" value="OSTLU_12811"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12811"/>
    <dbReference type="eggNOG" id="KOG2474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015114_1_3_1"/>
    <dbReference type="OMA" id="DVIVHKI"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF205">
        <property type="entry name" value="ZINC TRANSPORTER ZUPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="232" mass="24178" checksum="5C99ED328F186197" modified="2007-05-15" version="1">MTLSTLAGLATTLGAVVAVWKKPDARAMAFLLGVAIGVMTSLSFVELYAKNVIEHGFWSVTAATLGGAGTDDEKDAIAAGRVSRARLLRLGILMAFAMTLHNLPEGFAVACASYTTIGPTMAFAIGMHNVPEGIIIAAPVYAATGSRSRAILLATASGLSEPVGALIALKFMKPYLTPTRLEHLLAGTGGIMVAVCALELWPEARKCGNSDNMYRGVIFGAALMMLTLYLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2D5</accession>
    <name>A4S2D5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_16707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419733.1">
        <property type="nucleotide sequence ID" value="XM_001419696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2D5"/>
    <dbReference type="GeneID" id="5003734"/>
    <dbReference type="Gramene" id="ABO98026">
        <property type="protein sequence ID" value="ABO98026"/>
        <property type="gene ID" value="OSTLU_16707"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16707"/>
    <dbReference type="HOGENOM" id="CLU_1680846_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="157" mass="18217" checksum="972530588B13BF6E" modified="2007-05-15" version="1">MVCPNVDRHRVLALVDDLHEKHRFKDKDYKDVVEALSGKSDPLDVSDAKVVKIYFDEHRVTWNRTDYAVRQFQNKILQVVDTLDDPESTCPARVNWACSSIERSTLADIADLVARHGCTHLLTHSCSCCYTEQVFIRKIELIQDGSRPHRQHVRWTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2W2</accession>
    <name>A4S2W2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lecithin:cholesterol acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_1469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419605.1">
        <property type="nucleotide sequence ID" value="XM_001419568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2W2"/>
    <dbReference type="STRING" id="436017.A4S2W2"/>
    <dbReference type="GeneID" id="5003766"/>
    <dbReference type="Gramene" id="ABO97898">
        <property type="protein sequence ID" value="ABO97898"/>
        <property type="gene ID" value="OSTLU_1469"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1469"/>
    <dbReference type="eggNOG" id="KOG2369">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016065_2_0_1"/>
    <dbReference type="OMA" id="FYFLKWV"/>
    <dbReference type="OrthoDB" id="190846at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="56532" checksum="0D5CE5336C06D58D" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S319</accession>
    <name>A4S319_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_35116</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419840.1">
        <property type="nucleotide sequence ID" value="XM_001419803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S319"/>
    <dbReference type="STRING" id="436017.A4S319"/>
    <dbReference type="GeneID" id="5003508"/>
    <dbReference type="Gramene" id="ABO98133">
        <property type="protein sequence ID" value="ABO98133"/>
        <property type="gene ID" value="OSTLU_35116"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35116"/>
    <dbReference type="eggNOG" id="KOG2086">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029402_4_0_1"/>
    <dbReference type="OMA" id="QEWYTGG"/>
    <dbReference type="OrthoDB" id="25887at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01770">
        <property type="entry name" value="UBX_UBXN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.210:FF:000002">
        <property type="entry name" value="UBX domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="3">
        <location>
            <begin position="120"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="224"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32153" checksum="A5C33C51E99EC69A" modified="2007-05-15" version="1" fragment="single">SQSNVRGLRDVNERNDDASDSNGPDPQEWYTGGASSGQAVIDPRERPDARLASMFDSARAHGAMDGTAEDLNPNESRGARGGAATAFRGRGRTLNSSAEEEAADEEEASAATAANADDGIVSRVVTFWQNGFTVDDGPLRTFDDPANVAFMESIGRGEAPAELAPRSRTERVNINLVQRHEPYVPPKEPKYRAFGGSGRTLASDSEPAPASTAPASTVEWNVDESQPTTSIQIRLRDGSRLVAKFNTTHTVAHIHSFIARSRPDESFAYTLQLSGFPPKTLSDDDAVIADAGLAGAVVIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S336</accession>
    <name>A4S336_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419849.1">
        <property type="nucleotide sequence ID" value="XM_001419812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S336"/>
    <dbReference type="STRING" id="436017.A4S336"/>
    <dbReference type="GeneID" id="5003516"/>
    <dbReference type="Gramene" id="ABO98142">
        <property type="protein sequence ID" value="ABO98142"/>
        <property type="gene ID" value="OSTLU_16898"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16898"/>
    <dbReference type="eggNOG" id="KOG2654">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_691503_0_0_1"/>
    <dbReference type="OMA" id="GFRIPQE"/>
    <dbReference type="OrthoDB" id="6022at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070274">
        <property type="term" value="C:RES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018609">
        <property type="entry name" value="Bud13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051112">
        <property type="entry name" value="CWC26_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809:SF0">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09736">
        <property type="entry name" value="Bud13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="198"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="399" mass="43733" checksum="DDC2FA914DF8A04B" modified="2007-05-15" version="1">MATKEIEARAVRYMGIGDDGSGWTAVEEDGSGAGGRRRRHDSDSEEATAAAAAAPSRRARHDSDSEDDAGDASVPPEDAPTTSAGDGLQYDSDGDLIIPQEPAAAAAAAAAAGEPQYDSDGDFILPEEPSGQQELQYDSDGDLILPPDPLPEAPAEDNKKKSKEKKTKEHKMTDGTSTGLVSAAQVIMEAELKRKAEQARVAKMTDEQSGRGAATNYRDKATGKLMDSEEMKRRSENVKPKERERPVWATGVEQARQAKQYEVDLVKAKDTPFAHADIDADYEDKQRSAMRFGDPMAHLSRKKRHAESLNLPSVVDGLGLSMDDLKKSGFRIPQEVPPHSWLRRGVVAPHNRYGIKPGRHWDGVDRGTGFEAKMFRKKSELKERAQLEDADAEEHNEWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S345</accession>
    <name>A4S345_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_34654</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419650.1">
        <property type="nucleotide sequence ID" value="XM_001419613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S345"/>
    <dbReference type="STRING" id="436017.A4S345"/>
    <dbReference type="GeneID" id="5003859"/>
    <dbReference type="Gramene" id="ABO97943">
        <property type="protein sequence ID" value="ABO97943"/>
        <property type="gene ID" value="OSTLU_34654"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34654"/>
    <dbReference type="eggNOG" id="KOG3202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061883_3_0_1"/>
    <dbReference type="OMA" id="KMAMVMK"/>
    <dbReference type="OrthoDB" id="546861at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052324">
        <property type="term" value="P:plant-type cell wall cellulose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
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        </source>
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</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
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                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
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                <person name="Schmutz J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
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    <dbReference type="AlphaFoldDB" id="A4S438"/>
    <dbReference type="GeneID" id="5003927"/>
    <dbReference type="Gramene" id="ABO98320">
        <property type="protein sequence ID" value="ABO98320"/>
        <property type="gene ID" value="OSTLU_26272"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26272"/>
    <dbReference type="HOGENOM" id="CLU_1211511_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="229" mass="25633" checksum="A91E3E955849D111" modified="2007-05-15" version="1">MCWGTLHRACLPSTCAHATCEACFKAREPDASCAVCGEKYLARGAPGAFARDAARDAECERVYGDAREAYDAEEDRRALRTLKECFGYETSTAFAARDGDGDEDEDEDKDAATRTETVDEDDGAYEIEFRDVAAARQTSGEPDETRARLPVEFASAPKTAKVEALRRFVEEQGRGKYALCDEHGRYRWSRAHGSDKDSVLDPTKTLEDFFEPQLRRGEPIVAWFVSFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4A1</accession>
    <name>A4S4A1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pseudouridine synthase RsuA/RluA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_4215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420235.1">
        <property type="nucleotide sequence ID" value="XM_001420198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4A1"/>
    <dbReference type="STRING" id="436017.A4S4A1"/>
    <dbReference type="GeneID" id="5004300"/>
    <dbReference type="Gramene" id="ABO98528">
        <property type="protein sequence ID" value="ABO98528"/>
        <property type="gene ID" value="OSTLU_4215"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4215"/>
    <dbReference type="eggNOG" id="KOG1919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_12_1_1"/>
    <dbReference type="OMA" id="EPPVMAC"/>
    <dbReference type="OrthoDB" id="424794at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02557">
        <property type="entry name" value="PseudoU_synth_ScRIB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF40">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="90"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="357" mass="40092" checksum="87D7FDBBAE9D52C6" modified="2007-05-15" version="1" fragment="single">RYCAPYDFDFVCGVKARWAGRRLCDLFASEFPMRPKEYYVKAHAMGRLCAREHEDGPMLAGGNRVRHFIHRHEPPVMADEVRVLTVNDDVVSVWKPATVPVHPTGQYRRNTVLALLAASRRDLGRLFPIHRLDKNVSGLLLLARSSEAANEMRVKMEAREMRKEYVARVRGAFNDGDATPVSNVESLGFDSKGRVAIWRGKKGVTDLDERTLKSFKDASTKFTCIKTLVDGTSLVRCEPFTGRSHQIRAHLAMLGYPIANDVAYGGALVEVERARAIQHACDVTVLNEAGELVKDESLAIDYSAPRKSREQSSDLCPHCPRIVHAGDQAIDLEAIWLHCVRYSGEGWEFECPMPDWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4S6</accession>
    <name>A4S4S6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS family transporter: multidrug efflux</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_26513</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420488.1">
        <property type="nucleotide sequence ID" value="XM_001420451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4S6"/>
    <dbReference type="STRING" id="436017.A4S4S6"/>
    <dbReference type="GeneID" id="5004375"/>
    <dbReference type="Gramene" id="ABO98781">
        <property type="protein sequence ID" value="ABO98781"/>
        <property type="gene ID" value="OSTLU_26513"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26513"/>
    <dbReference type="eggNOG" id="ENOG502S4IK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_10_14_1"/>
    <dbReference type="OMA" id="GRTMAIY"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17325">
        <property type="entry name" value="MFS_MdtG_SLC18_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050171">
        <property type="entry name" value="MFS_Transporters"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23517:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23517">
        <property type="entry name" value="RESISTANCE PROTEIN MDTM, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="442" mass="44934" checksum="C145F6C9B2C45C94" modified="2007-05-15" version="1">MSGHACASPVLPMLAREFGANATEIGATMSAFAAGRLLFNLPCGWYADAVGRRPLMIAGPAATTAGMAWSYCSTGLGELLCARAVAGIGSSMYMSGATAMLADLSTRHTRARILGANQAAVLAGAAAGPALGGAIAGADGMSIRSPFLAVGALSSFASVYSFARIEETRPESVKPEREFAASKHWYCDGHPIEDTKMCLELDEFGKPVVHRDGQVYELLETKSPDGAATTTAVDPATAQDAAMGRLVKSMDFWAVCGLNAALFFSGAGGRGTLLPILAYQNFGFTPESLGALFSAMAVTSLLGLGPASALTDAVGRKAVIAPCVVASAASVALMGTTTDPTAFTAASILWAASGSLMGTAPAAYAADISPKNIRGSALAIYRTCGDVGLLLGPLALGALADEVGIPIALGVNAALLTISGGVFHFTAREIRRKAQTAAAKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S506</accession>
    <name>A4S506_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420527.1">
        <property type="nucleotide sequence ID" value="XM_001420490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S506"/>
    <dbReference type="GeneID" id="5004414"/>
    <dbReference type="Gramene" id="ABO98820">
        <property type="protein sequence ID" value="ABO98820"/>
        <property type="gene ID" value="OSTLU_26594"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26594"/>
    <dbReference type="HOGENOM" id="CLU_1339461_0_0_1"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="39"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="205" mass="22462" checksum="C08DEF9F5D0371B4" modified="2007-05-15" version="1">MGASARDGDDAGDGVRDDGDDANDANDEEEEEEDFVGACRVCLFDVTREDIRDARAVRLGCACVSGVVHVDAECLEAWVLRAPRKSADCEICLERMTNVPTRAELRKERRLRREKYRARTVSSSSSASARDDDARDDDARARDLEIGAERIGDVSRGERCCLYACAPLACAYAIVHAFCAHRSCVFAFILLAIGVAVLTRVSILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S512</accession>
    <name>A4S512_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_44226</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420363.1">
        <property type="nucleotide sequence ID" value="XM_001420326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S512"/>
    <dbReference type="GeneID" id="5004424"/>
    <dbReference type="Gramene" id="ABO98656">
        <property type="protein sequence ID" value="ABO98656"/>
        <property type="gene ID" value="OSTLU_44226"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44226"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_7_1"/>
    <dbReference type="OMA" id="CEYSPAR"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="6">
        <location>
            <begin position="71"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="328" mass="34792" checksum="F46665A4E359E0E1" modified="2007-05-15" version="1">MRFARLFAVFADDKEVNALRTCVPALDFEEDVEVFSQGVTTWSRDRLNGRDGLDGKLLPRDPPEDGYGSIVHVYLLDTGVRRTHVEFKDQAFGRGVDLVDDDAEPDDCDGHGSHVASTINQIAYSGKTVLHSVRVLDCNGNGELSGLIEGLEWVLGVATPSEPAVVSLALGVRNGIWSRALERVVQTLTGRGVFIVCAAGNQKGDACTISPGNVAETLTVAASDQADAPYAYGNSGRCVDLFAPGVQILGACGGSTACEHPSDTAYAFQSGTSMAVAHAVGAATRLLMFSPRMSPENLKKHLTSTASRDKIRGGSLLPGTPNLLLYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S534</accession>
    <name>A4S534_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_26622</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420540.1">
        <property type="nucleotide sequence ID" value="XM_001420503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S534"/>
    <dbReference type="STRING" id="436017.A4S534"/>
    <dbReference type="GeneID" id="5004435"/>
    <dbReference type="Gramene" id="ABO98833">
        <property type="protein sequence ID" value="ABO98833"/>
        <property type="gene ID" value="OSTLU_26622"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26622"/>
    <dbReference type="eggNOG" id="KOG1612">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038194_4_0_1"/>
    <dbReference type="OMA" id="MRKLACK"/>
    <dbReference type="OrthoDB" id="272245at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="11"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="93"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="191" mass="20148" checksum="DC22049F19C991CD" modified="2007-05-15" version="1">MGKREQFGIDLKSLCVKPGRARWTLTVDCACACDRGSMLDALSVGVRAALADTKIPKVTVAGVGEDGAGGELEIDDDPEACSRVDVSRCGVVVTTTKIGRHGVVDATEEETACSEATMSVGVDREGTICAEFGAGGESLDRGTAQAMRKLACKVGVELIEHMDGYLARAIAVDVDDDDEGDDRVLKVKIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5B1</accession>
    <name>A4S5B1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MIP family transporter: water channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_25291</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420576.1">
        <property type="nucleotide sequence ID" value="XM_001420539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5B1"/>
    <dbReference type="STRING" id="436017.A4S5B1"/>
    <dbReference type="GeneID" id="5004812"/>
    <dbReference type="Gramene" id="ABO98869">
        <property type="protein sequence ID" value="ABO98869"/>
        <property type="gene ID" value="OSTLU_25291"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25291"/>
    <dbReference type="eggNOG" id="KOG0223">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020019_3_0_1"/>
    <dbReference type="OMA" id="PAMVANH"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="28925" checksum="E694C71BEABC8EE0" modified="2007-05-15" version="1">MPAREMAVKRPTYAKDGLKSINARGCIIEFVATMTYVALCVPVQMMYGNGFTTAVTYGVVVTLLTYAFRKETVAQMNPSVSVTFMATGKITVEQMIGNIVSQIAGALIGVCWTCVWVAGGNDPTGYVGATLGYWGQANAGRVFFCETVANWLFLVTIVQATHPSLKQSAFFSSIFIGFAYYVCLLFTGSVSGGMINAARSFASACAGSIRIKGRAAPGAVVSTKILWDRHWIAWVAPMAGGAAAIVVDFFMTGFPEKKNTEAPHWLDATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5B3</accession>
    <name>A4S5B3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pentatrichopeptide repeat (PPR) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PPR6</name>
        <name evidence="5" type="ORF">OSTLU_25292</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420577.1">
        <property type="nucleotide sequence ID" value="XM_001420540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5B3"/>
    <dbReference type="STRING" id="436017.A4S5B3"/>
    <dbReference type="GeneID" id="5004813"/>
    <dbReference type="Gramene" id="ABO98870">
        <property type="protein sequence ID" value="ABO98870"/>
        <property type="gene ID" value="OSTLU_25292"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25292"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_361089_0_0_1"/>
    <dbReference type="OMA" id="FTRMQSS"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="241"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="433"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="437"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="524"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="775" mass="86283" checksum="D27E897C2A574832" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5J8</accession>
    <name>A4S5J8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_17568</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420622.1">
        <property type="nucleotide sequence ID" value="XM_001420585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5J8"/>
    <dbReference type="STRING" id="436017.A4S5J8"/>
    <dbReference type="GeneID" id="5004650"/>
    <dbReference type="Gramene" id="ABO98915">
        <property type="protein sequence ID" value="ABO98915"/>
        <property type="gene ID" value="OSTLU_17568"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17568"/>
    <dbReference type="eggNOG" id="KOG0779">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_346618_0_0_1"/>
    <dbReference type="OMA" id="FFYQKLA"/>
    <dbReference type="OrthoDB" id="568156at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="348"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="84"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="621"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="685"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="691"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="705"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="763"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="792"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="815" mass="92064" checksum="70F5957317950D0E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5W7</accession>
    <name>A4S5W7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_95019</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420843.1">
        <property type="nucleotide sequence ID" value="XM_001420806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5W7"/>
    <dbReference type="STRING" id="436017.A4S5W7"/>
    <dbReference type="GeneID" id="5004701"/>
    <dbReference type="Gramene" id="ABO99136">
        <property type="protein sequence ID" value="ABO99136"/>
        <property type="gene ID" value="OSTLU_95019"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_95019"/>
    <dbReference type="eggNOG" id="KOG2169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_728424_0_0_1"/>
    <dbReference type="OrthoDB" id="28127at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="6">
        <location>
            <begin position="102"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="305"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="380" mass="42013" checksum="06269B973924A07C" modified="2007-05-15" version="1">MQWPLDVYLTANDHTLTVVKRSTVKSVTKSTRDPSVRIPASRLRSGSNHFRMFHRDRRGAFMIALRIVRKRTLEEVAASIPKAASVGVALRNALKHLGFTEKDDEVIMEDVALVSLRCPISGQVCRNPARLSSCVGLHAFDAESFLQLNTVSRKWCCPECGKKGGPSDLRVDSFIKYCVDKVTERALSKVSRIEINKDGHWRPREDAGAPPLDASQLRCVTWKLDGDDGSPTSTATKVNGVTVAETPNVESKETIELVKTDDDGEDSELDEEEEYRRAIREAAEFCGAGGARAPGKRKREPDVIVISDSEDDNPVQRSAATQSTTKRPKCKPSSALTARPPGVPRSVDSLSPRSRAREIHFRMTHRPNPFCPTSTAPRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S677</accession>
    <name>A4S677_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MLO-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MLO</name>
        <name evidence="12" type="ORF">OSTLU_25379</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May be involved in modulation of pathogen defense and leaf cell death.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminus contains a calmodulin-binding domain, which binds calmodulin in a calcium-dependent fashion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MLO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420898.1">
        <property type="nucleotide sequence ID" value="XM_001420861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S677"/>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
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                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
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                <person name="Robbens S."/>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
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                <person name="Rouze P."/>
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                <person name="Putnam N."/>
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                <person name="Tai V."/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="143"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="34806" checksum="8C88D2A7ABF5B574" modified="2007-05-15" version="1">MSRRAATAVTLAVTLASLVRARAPRTARRGGDEGDARAAGAWTVGDAARATLASACVSLASLVGCALMAIGARADALAWLSDAAIGAMLGDALGCQLPSALEAATRARGRDGAGVAACATTCGVLAFHQLEVIVRAVKARNDGKVGTTRRRRTPSESRSRSRSRGASGRARERRAAAREIAASGWLNLFADAAHNFTDGVVIAIAFARRGATRGYAAAWTTLAHELPQELGDYGILRRSGFTDVEALWFNFLSALVAVGATALTFLVLAALDAASASASSFARRLALDVPYLVEAFCAGGFLTVAFTALREDDSGSAFARVRVFVAAVLVARRGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7F1</accession>
    <name>A4S7F1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ZIP family transporter: zinc ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_27457</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421262.1">
        <property type="nucleotide sequence ID" value="XM_001421225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7F1"/>
    <dbReference type="GeneID" id="5005307"/>
    <dbReference type="Gramene" id="ABO99555">
        <property type="protein sequence ID" value="ABO99555"/>
        <property type="gene ID" value="OSTLU_27457"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27457"/>
    <dbReference type="eggNOG" id="KOG2693">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_829996_0_0_1"/>
    <dbReference type="OMA" id="FYIVERV"/>
    <dbReference type="OrthoDB" id="200954at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="335" mass="34603" checksum="CE615639B3B979F5" modified="2007-05-15" version="1">MSRRAATAVTRAVTLASLVARARAHGARGGDEGDARAAGAWTVGDAARATLASACVSLASLVGCALMAIGARADALAWLSDAAIGAMLGDALGCQLPSALEAATRARGRDGAGVAACATTCGVLAFHQLEVIVRAVKARNDGKVGTTRRRRTPSESRSRSRSRGASGRARERRAAAREIAASGWLNLFADAAHNFTDGVVIAIAFARRGATRGYAAAWTTLAHELPQELGDYGILRRSGFTDVEALWFNFLSALVAVGATALTFLVLAALDAASASASSFARRLALDVPYLVEAFCAGGFLTVAFTALREDDSGSAFARVRVFVAAVLVARRGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7M8</accession>
    <name>A4S7M8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MC family transporter: uncoupling protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_5982</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421299.1">
        <property type="nucleotide sequence ID" value="XM_001421262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7M8"/>
    <dbReference type="GeneID" id="5005275"/>
    <dbReference type="Gramene" id="ABO99592">
        <property type="protein sequence ID" value="ABO99592"/>
        <property type="gene ID" value="OSTLU_5982"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5982"/>
    <dbReference type="eggNOG" id="KOG0753">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_14_3_1"/>
    <dbReference type="OMA" id="KHMMRFG"/>
    <dbReference type="OrthoDB" id="756301at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="94"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="189"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="274" mass="29158" checksum="281450DDCB1C81DC" modified="2007-05-15" version="1" fragment="single">PDVAREWAAAGVGCALADTVFNPLEVLKVRAQQRPDAVALRALAREAIARDGFARGLLAPGLAATWMRGLSYTGFRIGLYPTTRDEALRVFGGDGVGARVLAGAVTGGIGAVVFNPIDVVRVRMQSSECGYRSTVGAFAEVAREEGVRRGLWRGAGACVARAMTLSGSQLATYDVSKRWLLKNGTFSEDAPPLHFTCSFASGVVAQTVTQPVDTLKTLVMSNVGDKRGAMTIARDVIANHGVRGLYRGYFAAAARQGPVMTLQMPIVEALRRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7R9</accession>
    <name>A4S7R9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_723</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="entry name" value="EVH1_PP4R3"/>
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        <property type="entry name" value="P4R3-like_central_dom"/>
    </dbReference>
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        <property type="entry name" value="PH-like_dom_sf"/>
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        <property type="entry name" value="PP4R3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318">
        <property type="entry name" value="ATP SYNTHASE GAMMA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PP4R3 EVH1-like" evidence="5">
        <location>
            <begin position="3"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central" evidence="4">
        <location>
            <begin position="142"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="627"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="654" mass="76088" checksum="87847FA90953F47E" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S846</accession>
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        <recommendedName>
            <fullName evidence="6">Ribosomal RNA methyltransferase SPB1-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_89243</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO99992.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="rRNA_MeTfrase_SPB1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024576">
        <property type="entry name" value="rRNA_MeTfrase_Spb1_DUF3381"/>
    </dbReference>
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        <property type="entry name" value="DUF3381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07780">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA methyltransferase SPB1-like C-terminal" evidence="2">
        <location>
            <begin position="420"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="307"/>
        </location>
    </feature>
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        <location>
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            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="645"/>
        </location>
    </feature>
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        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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            <end position="194"/>
        </location>
    </feature>
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        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
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            <end position="259"/>
        </location>
    </feature>
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            <end position="279"/>
        </location>
    </feature>
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        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
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        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="71696" checksum="4EC35FFFA96A3D5A" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8K5</accession>
    <name>A4S8K5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA polymerase II subunit A C-terminal domain phosphatase SSU72</fullName>
            <shortName evidence="9">CTD phosphatase SSU72</shortName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_40630</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SSU72 phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421639.1">
        <property type="nucleotide sequence ID" value="XM_001421602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8K5"/>
    <dbReference type="STRING" id="436017.A4S8K5"/>
    <dbReference type="GeneID" id="5005719"/>
    <dbReference type="Gramene" id="ABO99932">
        <property type="protein sequence ID" value="ABO99932"/>
        <property type="gene ID" value="OSTLU_40630"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40630"/>
    <dbReference type="eggNOG" id="KOG2424">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062463_2_1_1"/>
    <dbReference type="OMA" id="PNCYEFG"/>
    <dbReference type="OrthoDB" id="57957at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006811">
        <property type="entry name" value="RNA_pol_II_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20383">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04722">
        <property type="entry name" value="Ssu72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU369031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="199" mass="22681" checksum="417735C786B3FFD4" modified="2007-05-15" version="1">MSAERKRYAVVCAANFNRSMEAHKVLAERGLDVASFGAASRVKLPGASRDDPNVYDFDSITYEDIASDLERQPRETVENYEARGMFEMLRRNAKIKPAPQRWQTHSDRERFDVVVCFEERVFDLVMEDLRAKGGAREGVLVVNLDVRDSHDSSVDAAPRALRLCEALEASEDWESEVDEIMNAFEEAEGMRPLYGVCYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8R9</accession>
    <name>A4S8R9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">nitric-oxide synthase (NADPH)</fullName>
            <ecNumber evidence="4">1.14.13.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_37787</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOS family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.39" evidence="4"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421937.1">
        <property type="nucleotide sequence ID" value="XM_001421900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8R9"/>
    <dbReference type="SMR" id="A4S8R9"/>
    <dbReference type="STRING" id="436017.A4S8R9"/>
    <dbReference type="GeneID" id="5005965"/>
    <dbReference type="Gramene" id="ABP00231">
        <property type="protein sequence ID" value="ABP00231"/>
        <property type="gene ID" value="OSTLU_37787"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37787"/>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_16_0_1"/>
    <dbReference type="OMA" id="MQLPTHG"/>
    <dbReference type="OrthoDB" id="1688044at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004517">
        <property type="term" value="F:nitric-oxide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006809">
        <property type="term" value="P:nitric oxide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.340.10">
        <property type="entry name" value="Nitric Oxide Synthase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1230.10">
        <property type="entry name" value="Nitric Oxide Synthase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.440.10">
        <property type="entry name" value="Nitric Oxide Synthase,Heme Domain,Chain A domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050607">
        <property type="entry name" value="NOS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044943">
        <property type="entry name" value="NOS_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044940">
        <property type="entry name" value="NOS_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044944">
        <property type="entry name" value="NOS_dom_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012144">
        <property type="entry name" value="NOS_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004030">
        <property type="entry name" value="NOS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036119">
        <property type="entry name" value="NOS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43410:SF1">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43410">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02898">
        <property type="entry name" value="NO_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000333">
        <property type="entry name" value="NOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56512">
        <property type="entry name" value="Nitric oxide (NO) synthase oxygenase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="5 14" id="KW-0349">Heme</keyword>
    <keyword evidence="13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="15">
        <location>
            <begin position="451"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="648"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000333-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABP00231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1059" mass="118273" checksum="5788592B652304D5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8T2</accession>
    <name>A4S8T2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GUN4-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_10367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421945.1">
        <property type="nucleotide sequence ID" value="XM_001421908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8T2"/>
    <dbReference type="STRING" id="436017.A4S8T2"/>
    <dbReference type="GeneID" id="5005989"/>
    <dbReference type="Gramene" id="ABP00239">
        <property type="protein sequence ID" value="ABP00239"/>
        <property type="gene ID" value="OSTLU_10367"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10367"/>
    <dbReference type="eggNOG" id="ENOG502QWGS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067449_4_0_1"/>
    <dbReference type="OMA" id="SVQKEIW"/>
    <dbReference type="OrthoDB" id="4835at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046906">
        <property type="term" value="F:tetrapyrrole binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010019">
        <property type="term" value="P:chloroplast-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1770">
        <property type="entry name" value="Gun4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800">
        <property type="entry name" value="TETRAPYRROLE-BINDING PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800:SF1">
        <property type="entry name" value="TETRAPYRROLE-BINDING PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="GUN4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GUN4-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="146" mass="17262" checksum="9594732D3D5F0EDB" modified="2007-05-15" version="1" fragment="single">LRRQMGVDYAPFKALLEAGEWEKADDEHRRLMCVLAGEDAEDREWVYFTEVDNMPATDLRTIDELWKFYSNNRFGFSVQRKIWISQKKQWAKFFKKIDWTTGENGDYRKFPQEFQWRADAAPGHMPLTNALRGTQLLAALLEHPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8V2</accession>
    <name>A4S8V2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421824.1">
        <property type="nucleotide sequence ID" value="XM_001421787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8V2"/>
    <dbReference type="GeneID" id="5006114"/>
    <dbReference type="Gramene" id="ABP00118">
        <property type="protein sequence ID" value="ABP00118"/>
        <property type="gene ID" value="OSTLU_27979"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27979"/>
    <dbReference type="HOGENOM" id="CLU_988297_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="191"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="282" mass="30269" checksum="D406ECAEAC53BF12" modified="2007-05-15" version="1">MDADALARELREENASLRREIEALRERSATREIEFRQELRALAAQCASLAAAAAVTSASAAATTEATQTEATVSADAHGGEWRVGGGHGVGGRPRRSARAPPTAWEVPNAWPMGAENADRASARSGEVSDRVRDAVEEEARRRGRGRRGVDADAFVGDLSSFFFKTAKHEAPVWESKKSTKSNDIDATSILRSARDGASEDDVDADAFGASSRPARETDPFDRSRGRPASSLDVEDEREADLTDSLRDDDDLVDALLRGGRDGERAAETLASRLRAVGFADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S968</accession>
    <name>A4S968_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_37806</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421883.1">
        <property type="nucleotide sequence ID" value="XM_001421846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S968"/>
    <dbReference type="STRING" id="436017.A4S968"/>
    <dbReference type="GeneID" id="5006051"/>
    <dbReference type="Gramene" id="ABP00177">
        <property type="protein sequence ID" value="ABP00177"/>
        <property type="gene ID" value="OSTLU_37806"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37806"/>
    <dbReference type="eggNOG" id="KOG0070">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040729_9_3_1"/>
    <dbReference type="OMA" id="RRWHVQA"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016004">
        <property type="term" value="F:phospholipase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABP00177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="211" mass="23616" checksum="D42A0C363D86B15A" modified="2007-05-15" version="1">MGAALSQARTLFDKYFGNVDMRVVMLGLDAAGKTTILYKLHIGEVLSTVPTLGFNVEKVQYKNVVFTVWDVGGQEKLRPLWRHYFNNTDGLIFVVDCLDRERARRAKEEFYSIVNDAFMRNSAILIFANKQDLKGAMTTAELVEAFELPSLKGRRWHVQASCATQGLGLYEGLDWLSSTLTKMRRNGVVTSVGSSGERHGAGRQGRSARFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S979</accession>
    <name>A4S979_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_13360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421889.1">
        <property type="nucleotide sequence ID" value="XM_001421852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S979"/>
    <dbReference type="STRING" id="436017.A4S979"/>
    <dbReference type="MEROPS" id="C19.094"/>
    <dbReference type="GeneID" id="5006056"/>
    <dbReference type="Gramene" id="ABP00183">
        <property type="protein sequence ID" value="ABP00183"/>
        <property type="gene ID" value="OSTLU_13360"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13360"/>
    <dbReference type="eggNOG" id="KOG1872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017549_2_1_1"/>
    <dbReference type="OMA" id="FKSDAEY"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="114"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="461" mass="51089" checksum="1DD43217807C4E66" modified="2007-05-15" version="1">MTTRVTIGVKHGKETHDVDVDLDESGATFKARLCSLTKVPIERIKVTGLKGGRPLADDADMRTQGVEALARRGKKLLMLGSAATLAKPAEEVAFLEDLPEGERDAANAGEGYRPGLTNLGNTCYANSVVQCLYAVEGLRDSLGGYAGGRDARGGTAALTTALRDLFGDVKTAKDTVMPVRFLNVLRQLYPQFAQHGPQGVPMQQDAEECWSAVMHTLATEQPEETRRLFGIGMRRELRCAATNETRVEDSVEYTFKCNITIEVNHVTEGFKIALNDTRELRSEVLGADAVFEGQSKISKLPDYLTTQLVRFYYKADIRAKAKILRAVTFPITLDVYEFCTDELKAELEPARKLKLKREDDEALKRVNEKKAALEDPASMEVVDPLEGTRFTGFFDLVSVLTHKGRSADSGHYVSWVKKDDGSWTEFDDETPIPRTEEDVLALKGGGDHHMSYILCYKARKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9J6</accession>
    <name>A4S9J6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_93911</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422182.1">
        <property type="nucleotide sequence ID" value="XM_001422145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9J6"/>
    <dbReference type="STRING" id="436017.A4S9J6"/>
    <dbReference type="GeneID" id="5006137"/>
    <dbReference type="Gramene" id="ABP00499">
        <property type="protein sequence ID" value="ABP00499"/>
        <property type="gene ID" value="OSTLU_93911"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93911"/>
    <dbReference type="eggNOG" id="KOG1677">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045191_0_0_1"/>
    <dbReference type="OMA" id="VRQLIMH"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051252">
        <property type="term" value="P:regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000003">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="27584" checksum="F8D97DBFF94E89FD" modified="2007-05-15" version="1">MGPANANDEKLCAKFFSIHGCAYGADCHFLHTYRPGLPVPPRPAPLPYVYTMSDAMRPQVNEKIKTRLCRNFESPQGCRFGDRCVFAHGEEELRTEEANTASMGSTYMLQTSIEQAVLVPVPQVHVGAIVGKAGSAIAQVSATSGAKVSMLSAEYTNSDGNRLCRVIGSPLDVQRAQEMIYQRLTYAERKKSDAPKDSKKKPFKTKICDSWVRNGQCPFGRRCHYAHGNEELQQRHSTNENSENVVIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9T1</accession>
    <name>A4S9T1_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422120.1">
        <property type="nucleotide sequence ID" value="XM_001422083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9T1"/>
    <dbReference type="STRING" id="436017.A4S9T1"/>
    <dbReference type="GeneID" id="5006283"/>
    <dbReference type="Gramene" id="ABP00437">
        <property type="protein sequence ID" value="ABP00437"/>
        <property type="gene ID" value="OSTLU_18694"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18694"/>
    <dbReference type="HOGENOM" id="CLU_352817_0_0_1"/>
    <dbReference type="OMA" id="SEECHCA"/>
    <dbReference type="OrthoDB" id="549905at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="797" mass="83405" checksum="DCBCE0371DDE4B92" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9V4</accession>
    <name>A4S9V4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">HAM3501</name>
        <name evidence="16" type="ORF">OSTLU_42025</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422236.1">
        <property type="nucleotide sequence ID" value="XM_001422199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9V4"/>
    <dbReference type="STRING" id="436017.A4S9V4"/>
    <dbReference type="GeneID" id="5006191"/>
    <dbReference type="Gramene" id="ABP00553">
        <property type="protein sequence ID" value="ABP00553"/>
        <property type="gene ID" value="OSTLU_42025"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42025"/>
    <dbReference type="eggNOG" id="KOG2747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011815_2_2_1"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF219">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="15">
        <location>
            <begin position="137"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="89"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="13">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABP00553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="458" mass="51630" checksum="3A218B102319D990" modified="2007-05-15" version="1">MRAPKTNAPARPDAFAAIDARAAFAVGARVRVRDGANEADGADAREGVVAARRGDGASATDGEVKYYVRYDATGVADEWVRVERLTSAGGESVGGSETTGGGSRSDAATAARAAAAAAAARKRKTTGEKDGGERGEEGGRKVRWIELGRYICDCWFDSPFPEEYTDERKLFVCDFCLKYHRKRRAYIAHKKTCELRHPPGNEIYRHPERQATEKSPARAQLRMWEVDGSNATTYCQNLCLIAKLFLDHKTLYYDVAAFYFYVLTERDFDESGKPLYRIIGYFSKEKGQVETNLACILTLPPYQRRGYGGFLIEFSYELAKREGRIGTPERPLSDLGFASYRTYWSRVIYESLSSTSAGGVNVAELSKKTNIRVDDIVSTLQPFSSIRFFKDQGFLNITKEGKQDFKAAQVKLREKWSELRVIPERLQFEPKINAVVEVAEKRRRTRLFQRDILENNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA86</accession>
    <name>A4SA86_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">BCCT family transporter: carnitine/choline</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_1494</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422299.1">
        <property type="nucleotide sequence ID" value="XM_001422262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA86"/>
    <dbReference type="GeneID" id="5006397"/>
    <dbReference type="KEGG" id="olu:OSTLU_1494"/>
    <dbReference type="eggNOG" id="ENOG502QRGP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010118_5_0_1"/>
    <dbReference type="OMA" id="WAMYALM"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047:SF7">
        <property type="entry name" value="HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673167" evidence="8">
        <location>
            <begin position="19"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="471" mass="52688" checksum="29482FB2F2ABDE86" modified="2007-05-15" version="1" fragment="single">LLWGFIIWVLVDETGSSSEVTRWTKWITSNFTWLYVVTQDVWFIFILYLLGTKYKDVKLGRDDEEPAFDYYEWFSMMFACGIGVGLYTFSVMEPISYYRGVVSKLPIVNDDQRAQQAITLTLFHWGLHGWIPYVLVAMTLGVVCYRHGRPMTIRSAFYPLFGENINGLFGDAIDALSIATTTFGVCTSLGLGVTTIASTMNRLNSDVDPNDDATKILIIWLITAVACTSVILGLKNGIRRLSKITFSIGLILLFGIIVADNPWFLLNSFVQSMGHYLNTMWGVRTDDGFMNTWTLFYWGWWISWAPFVGMFIARISRGRTVGEVIKGAFIAPILFGFFYLTVLGSLGIKMERIAELALTTAPADVDWRSGDPYGKLSTLFQAMILIAIILYFITSSDSGSYVDDLISAMGYENPPVLQKVYWACTEGALAQALVTSGGLKVVQGVSIVCGLPFTFALNFMVVSLWRALKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAC9</accession>
    <name>A4SAC9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_42201</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422413.1">
        <property type="nucleotide sequence ID" value="XM_001422376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAC9"/>
    <dbReference type="SMR" id="A4SAC9"/>
    <dbReference type="STRING" id="436017.A4SAC9"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="5006423"/>
    <dbReference type="Gramene" id="ABP00730">
        <property type="protein sequence ID" value="ABP00730"/>
        <property type="gene ID" value="OSTLU_42201"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42201"/>
    <dbReference type="eggNOG" id="ENOG502QS4Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031603_0_1_1"/>
    <dbReference type="OMA" id="SDIWLPH"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="10"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="321" mass="37401" checksum="20D9866AB1A4A1C2" modified="2007-05-15" version="1" fragment="single">WLRYAMLGNETERRWVFETLDAMREIGADVARTWAFLDGDESSYDGRSTQPRRGEFNERAFVGLDEVLYECERRRIRVILTLTNYWDDYGGIARYARWAREEGETSAYRREDFFTSPKCRDAFEAFVAKVVTRTNTFTNVAYKDDPTIFAYQLINEPRLPGDDRGDVFHEWATYFGALVKRLDEGNHLVSVGTEGFFMRGEGVEANPFAGAERQGVDVDRLRESDAVDFVAAHVWTDDWMDSDDESKLRFLERWIRAHLAKSANDKPIVFEEFGKKRPLAVRDAYFARTFELLREDDRRRAGALFWLLSPAEIEDYDGFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAL6</accession>
    <name>A4SAL6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422633.1">
        <property type="nucleotide sequence ID" value="XM_001422596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAL6"/>
    <dbReference type="GeneID" id="5006511"/>
    <dbReference type="Gramene" id="ABP00950">
        <property type="protein sequence ID" value="ABP00950"/>
        <property type="gene ID" value="OSTLU_25817"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25817"/>
    <dbReference type="HOGENOM" id="CLU_1328295_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="22955" checksum="58DE3FA725E81E32" modified="2007-05-15" version="1">MSRRDGRRRRPRAREDVVTTLLRRREARARATRAGDDDDAGENDAFVDAAETWATDDGRGRREATTTRTSRSSASASSSSSSASSYASARAREDEDEDAKAWTSTRDARELGWGPRPSNEARERAARAKALAKRLLEGDEDEPTARGEIVGGEVARDVGSERLRSVLTIDSATSGGDSDPERLAKRRARRRAAKRRHERRLREGVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAV2</accession>
    <name>A4SAV2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FBP14-2</name>
        <name evidence="3" type="ORF">OSTLU_29389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422504.1">
        <property type="nucleotide sequence ID" value="XM_001422467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAV2"/>
    <dbReference type="STRING" id="436017.A4SAV2"/>
    <dbReference type="GeneID" id="5006725"/>
    <dbReference type="Gramene" id="ABP00821">
        <property type="protein sequence ID" value="ABP00821"/>
        <property type="gene ID" value="OSTLU_29389"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29389"/>
    <dbReference type="eggNOG" id="KOG0549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1654494_0_0_1"/>
    <dbReference type="OMA" id="MPRMRIG"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="2">
        <location>
            <begin position="55"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="177" mass="18885" checksum="009E4FD563AB6AC0" modified="2007-05-15" version="1">MLARRDALLSAALSAGALARPRRARAAPAPTFAPTRDGVRFRDARVGDGPEVFAHDAVVILFTARVLPSDDGALDRRRAGDTFDPFVVGGAGASASKGFKLEIGSATNDIPEGWARAFEGDGDAMPRMRIGGKRIVRIPPSLAYGERGHHCRDGVRGACEVNPGESVEIDFEILRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB27</accession>
    <name>A4SB27_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RPA43 OB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_25861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422704.1">
        <property type="nucleotide sequence ID" value="XM_001422667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB27"/>
    <dbReference type="STRING" id="436017.A4SB27"/>
    <dbReference type="GeneID" id="5006761"/>
    <dbReference type="Gramene" id="ABP01021">
        <property type="protein sequence ID" value="ABP01021"/>
        <property type="gene ID" value="OSTLU_25861"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25861"/>
    <dbReference type="eggNOG" id="KOG4134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_938092_0_0_1"/>
    <dbReference type="OMA" id="HTGSIHW"/>
    <dbReference type="OrthoDB" id="497899at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041178">
        <property type="entry name" value="RPA43_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17875">
        <property type="entry name" value="RPA43_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RPA43 OB" evidence="6">
        <location>
            <begin position="127"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="232"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP01021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="32517" checksum="52AE5F9B6E6378BA" modified="2007-05-15" version="1">MARPRADDARASSAVATRSCVFTVALHPSALADPLAGARAVLDAMKMRHVDALGGVLMAYDDEALCGARRRERDDDGDDDGDDETSTSESDDAEADDDDGRGGFGRVLHASGHVDVRVRARCEVFTPVKESRLVGTVNKIAHDFIGALVLDRFNVAIAAENIREELVSSSDDGCWRSAWDATHVIKVGSQIVFTVKAVTESDDVVLLRGAMKDPATGEREYVARSSSGITSIERKLVAPADSDSRREKKSKKEKEKKEKKEKKEKKEKKEKKEKRKSENDLEKSDGRSSKRAKDSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBK2</accession>
    <name>A4SBK2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ATP-binding) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_29639</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422787.1">
        <property type="nucleotide sequence ID" value="XM_001422750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBK2"/>
    <dbReference type="STRING" id="436017.A4SBK2"/>
    <dbReference type="GeneID" id="5006845"/>
    <dbReference type="Gramene" id="ABP01146">
        <property type="protein sequence ID" value="ABP01146"/>
        <property type="gene ID" value="OSTLU_29639"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29639"/>
    <dbReference type="eggNOG" id="KOG0060">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_491267_0_0_1"/>
    <dbReference type="OMA" id="DATCAMD"/>
    <dbReference type="OrthoDB" id="422637at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF59">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORTER ABCD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="386"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="661"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP01146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="684" mass="73448" checksum="AA9B137A19C6A7E1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBZ8</accession>
    <name>A4SBZ8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_89893</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422950.1">
        <property type="nucleotide sequence ID" value="XM_001422913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBZ8"/>
    <dbReference type="STRING" id="436017.A4SBZ8"/>
    <dbReference type="GeneID" id="5006919"/>
    <dbReference type="Gramene" id="ABP01309">
        <property type="protein sequence ID" value="ABP01309"/>
        <property type="gene ID" value="OSTLU_89893"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89893"/>
    <dbReference type="eggNOG" id="ENOG502QQ6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002399_0_1_1"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054481">
        <property type="entry name" value="GWD1_pHisD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46999:SF1">
        <property type="entry name" value="ALPHA-GLUCAN WATER DIKINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46999">
        <property type="entry name" value="ALPHA-GLUCAN WATER DIKINASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22973">
        <property type="entry name" value="GWD1_pHisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-glucan water dikinase phosphohistidine-like" evidence="12">
        <location>
            <begin position="163"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="11">
        <location>
            <begin position="431"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP01309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="635" mass="68401" checksum="71C34F495341F9BE" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQD2</accession>
    <name>A4RQD2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_44556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415368.1">
        <property type="nucleotide sequence ID" value="XM_001415331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQD2"/>
    <dbReference type="GeneID" id="4999663"/>
    <dbReference type="Gramene" id="ABO93660">
        <property type="protein sequence ID" value="ABO93660"/>
        <property type="gene ID" value="OSTLU_44556"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44556"/>
    <dbReference type="eggNOG" id="ENOG502QU5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042215_1_0_1"/>
    <dbReference type="OMA" id="CPGQWSF"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF2">
        <property type="entry name" value="LYSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="484" mass="53243" checksum="6984D75F5EC1365B" modified="2007-05-15" version="1" fragment="single">MTLPARASTSTFVRGAATTSDGNAVRQARYIGARRRSSRARAVMPETLEALPTSPTTAGAALGLAGAALGAAAALRGRLGGGARGGNSNAQADRSSRTAMTRGTGESDESKGRRYLIAPPPLFPLVPAFARQTYRYEVDPGRMWFFEQKQGIGLGLNVSVNVRMTVIKLKTGGLWVHAPVAPTAEMVALLDELDAPVEHVVLPTTLFEHKIFVGPFQRKYPKAQCWIVPQQWSWPINLPPQFFGINKTGTLGQDRPPWDDEFEYELLSPPALGVASYVSFIEAAFLHKPSKTLLVTDAVVYVSENIPDCIPDRDLEESGDDDNFTISALKFLNLFDIKTKALSRTTTSKDMSRLELLRLGWQRNALQALYFGPNDLLSPEKSWRDITNRLIVAPVVGTLVYENVPEPVNEWARRVAKWDFNRIVPCHFDAPIRAGPREFSAAFSFLPSSRPEKAKGRGGGKYYPNEDMILLRGVADFLLNTGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQD9</accession>
    <name>A4RQD9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat Shock Protein 90</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HSP90C</name>
        <name evidence="7" type="ORF">OSTLU_23829</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415715.1">
        <property type="nucleotide sequence ID" value="XM_001415678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQD9"/>
    <dbReference type="STRING" id="436017.A4RQD9"/>
    <dbReference type="GeneID" id="4999847"/>
    <dbReference type="Gramene" id="ABO94007">
        <property type="protein sequence ID" value="ABO94007"/>
        <property type="gene ID" value="OSTLU_23829"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_23829"/>
    <dbReference type="eggNOG" id="KOG0019">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006684_1_3_1"/>
    <dbReference type="OMA" id="GIEQHQY"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="6">
        <location>
            <begin position="44"/>
            <end position="202"/>
        </location>
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    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
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            <position position="102"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
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            <end position="118"/>
        </location>
        <ligand>
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        </location>
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            <position position="398"/>
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        <ligand>
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        </ligand>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="711" mass="79794" checksum="8B95AAB643D20AE9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQK3</accession>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">OSTLU_13608</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="297"/>
        </location>
    </feature>
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        <location>
            <begin position="1606"/>
            <end position="1795"/>
        </location>
    </feature>
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        <location>
            <begin position="1534"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2120"/>
            <end position="2142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2130"/>
            <end position="2142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="2142" mass="230763" checksum="19E65B6FC7C8ECFF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQN8</accession>
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        <recommendedName>
            <fullName evidence="5">4Fe-4S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="6" type="ORF">OSTLU_7956</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
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            <dbReference type="PubMed" id="17460045"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415382.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABO93711"/>
        <property type="gene ID" value="OSTLU_7956"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7956"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118293_0_0_1"/>
    <dbReference type="OMA" id="HWVEREQ"/>
    <dbReference type="OrthoDB" id="566614at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45295">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ C76, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45295:SF1">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ C76, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13370">
        <property type="entry name" value="Fer4_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="136"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="167" mass="19351" checksum="66D693510A40AA09" modified="2007-05-15" version="1" fragment="single">FTGNPYSKWTTRKAKPGETRAVFVDEFTCIGCKQCVWQAPATFRMNDDYGRSRVFAQWLNDEDDIQCAIDSCPVDCIHWVEREQLPFLEHVAVNYEKVSVGIMQSQTGVVTDPFEAASSFQKMRQRKIDARAEELAEQRRRMTDEEKRANTSEAQRRAYRKSADAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR18</accession>
    <name>A4RR18_OSTLU</name>
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        <recommendedName>
            <fullName evidence="1">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415789.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABO94118"/>
        <property type="gene ID" value="OSTLU_13731"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13731"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
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        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="75"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO94118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="310" mass="34511" checksum="71E5261071430B86" modified="2007-05-15" version="1">MCPLGNRRATLRRFLVARKYSLDNAEAALREAMEWRKTVKIGDRVGVDAILASEPRWDLLADNRKIMTGTPFLCYTKQGFPVYMLRLGKGDAALATSASDETHVYSTIVRAEHLVQSIIPEATERAKKIKAEGKEQEASSDDYDGLVDKQVVIIDMDGIGMSALRCLYVLKTINSVASHNYPELSKAIYVVNAPSAFDYLWSAVKPLLAVHTQHKIKIFSQAESQYTGLQRLLEDEDIPDFLVPEGHTPGQKDCVTTVDGFLPTTVKKMDDWLKCLCSEQEGETKGDEEVSATIEKMSAIEIKEDYAAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR19</accession>
    <name>A4RR19_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cleavage and polyadenylation specificity factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cleavage and polyadenylation specificity factor 100 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_12108</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415490.1">
        <property type="nucleotide sequence ID" value="XM_001415453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR19"/>
    <dbReference type="STRING" id="436017.A4RR19"/>
    <dbReference type="GeneID" id="4999582"/>
    <dbReference type="Gramene" id="ABO93782">
        <property type="protein sequence ID" value="ABO93782"/>
        <property type="gene ID" value="OSTLU_12108"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12108"/>
    <dbReference type="eggNOG" id="KOG1135">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002227_1_1_1"/>
    <dbReference type="OMA" id="QSRHNME"/>
    <dbReference type="OrthoDB" id="64353at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16293">
        <property type="entry name" value="CPSF2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000008">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027075">
        <property type="entry name" value="CPSF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025069">
        <property type="entry name" value="Cpsf2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035639">
        <property type="entry name" value="CPSF2_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922:SF1">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13299">
        <property type="entry name" value="CPSF100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Beta-Casp" evidence="8">
        <location>
            <begin position="225"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="375"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO93782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="715" mass="78571" checksum="4F5C3C8A6DF3E44F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR47</accession>
    <name>A4RR47_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_5500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_5500"/>
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    <dbReference type="eggNOG" id="KOG1601">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:cytokinin-activated signaling pathway"/>
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        <property type="term" value="P:phosphorelay signal transduction system"/>
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    </dbReference>
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        <property type="entry name" value="SANT/Myb"/>
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        <property type="entry name" value="myb_SHAQKYF"/>
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    </dbReference>
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        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR ARR10"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036392">
        <property type="entry name" value="RR_ARR_type-B"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="2 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
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        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="12">
        <location>
            <begin position="195"/>
            <end position="254"/>
        </location>
    </feature>
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        <location>
            <begin position="128"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
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        <location>
            <position position="57"/>
        </location>
    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO93800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="29628" checksum="69826914C774A878" modified="2007-05-15" version="1" fragment="single">FPAGLGVLVVDDDLLCLKVVEKMLKACKYKVTACSTAKTALEILRTRKEEFDIVLSDVHMPDMDGFKLLEIIQFELALPVLMMSANSDSSVVLRGIIHGAVDYLLKPVRIEELRNIWQHVVRRDYSSAKSSGSEDVEASSPSKRAKTSGSNSKSEEVDRTASEMSSGKARKKPTGKKGGKSVKEAEKKDVVDNSNSKKPRVVWSAELHAQFVTAVNQLGIDKAVPKRILDLMGVQGLTRENVASHLQKYRLYLKRLQGNDARGGGNASST</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR55</accession>
    <name>A4RR55_OSTLU</name>
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        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001415477.1"/>
    </dbReference>
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        <property type="gene ID" value="OSTLU_92132"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="445803at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="71"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="157" mass="17407" checksum="FE318B92ABBD0E92" modified="2007-05-15" version="1">MATARDDGRFNPSPALARDVEASGARYPPVKVRAASLGTVKARALHHQATEEMVRDLLKYDEVPGITNMSHVALPPGTVIDRHVHPSKYEVFFVQSGRGAFKVWRRKASEAEEAREEIDLRPGVSVYVGPEEPHEIIPHGEDEPLMMLYFGVVAPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRF0</accession>
    <name>A4RRF0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415559.1">
        <property type="nucleotide sequence ID" value="XM_001415522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRF0"/>
    <dbReference type="GeneID" id="4999611"/>
    <dbReference type="Gramene" id="ABO93851">
        <property type="protein sequence ID" value="ABO93851"/>
        <property type="gene ID" value="OSTLU_28994"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28994"/>
    <dbReference type="HOGENOM" id="CLU_334454_0_0_1"/>
    <dbReference type="OrthoDB" id="2448405at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1910.20">
        <property type="entry name" value="asparaginyl-tRNA synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IPT/TIG" evidence="1">
        <location>
            <begin position="51"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="854" mass="90657" checksum="FB8CFE2E17C2565D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRF2</accession>
    <name>A4RRF2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_23918</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415560.1">
        <property type="nucleotide sequence ID" value="XM_001415523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRF2"/>
    <dbReference type="STRING" id="436017.A4RRF2"/>
    <dbReference type="GeneID" id="4999523"/>
    <dbReference type="Gramene" id="ABO93852">
        <property type="protein sequence ID" value="ABO93852"/>
        <property type="gene ID" value="OSTLU_23918"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_23918"/>
    <dbReference type="eggNOG" id="KOG0845">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012217_0_0_1"/>
    <dbReference type="OMA" id="GDILWPG"/>
    <dbReference type="OrthoDB" id="498759at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034398">
        <property type="term" value="P:telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.10">
        <property type="entry name" value="Peptidase S59, nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007230">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036903">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04096">
        <property type="entry name" value="Nucleoporin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82215">
        <property type="entry name" value="C-terminal autoproteolytic domain of nucleoporin nup98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51434">
        <property type="entry name" value="NUP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S59" evidence="12">
        <location>
            <begin position="863"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="735"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="755"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO93852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1000" mass="94149" checksum="5CDE2B5075D42432" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRH7</accession>
    <name>A4RRH7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Core Histone H2A/H2B/H3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HTR3504</name>
        <name evidence="4" type="ORF">OSTLU_29021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415904.1">
        <property type="nucleotide sequence ID" value="XM_001415867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRH7"/>
    <dbReference type="STRING" id="436017.A4RRH7"/>
    <dbReference type="GeneID" id="4999902"/>
    <dbReference type="Gramene" id="ABO94196">
        <property type="protein sequence ID" value="ABO94196"/>
        <property type="gene ID" value="OSTLU_29021"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29021"/>
    <dbReference type="eggNOG" id="KOG1745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078295_7_1_1"/>
    <dbReference type="OMA" id="VHLFEDC"/>
    <dbReference type="OrthoDB" id="652632at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000088">
        <property type="entry name" value="Histone H3-like centromeric protein CSE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="3">
        <location>
            <begin position="37"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="135" mass="15715" checksum="E3FD6E39E45FA8AB" modified="2007-05-15" version="1">MARRLHGKRFKAPQRRLSGADGAERQELDKKKRRYRPGTLALKEIRRFQKTTDLLIRKMPFARLVREISNELSPEPLRYTAESLLALQEATEDFLVHLFEDCNLCAIHAKRVTIMPKDLQLARRIRGPIYGVAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS09</accession>
    <name>A4RS09_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polymerase nucleotidyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29204</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
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                <person name="Napoli C."/>
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                <person name="Tai V."/>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
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                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
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                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="olu:OSTLU_92245"/>
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    <dbReference type="OMA" id="ERSVCAM"/>
    <dbReference type="OrthoDB" id="498062at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672841" evidence="2">
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            <end position="198"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="198" mass="21571" checksum="26D2A33992DB78B5" modified="2007-05-15" version="1" fragment="single">LDAAEFACRCISLYIILVLSSDPPCADSSTLRAVQKVSTTRHHDARALAIAMATTSAMTIERSVCAMRARSSSSTSTRTTARSRATVAVKKNVYSRTSVVVARAYGDDDENMRVKGRMPQEGDRVGDREDPDLYIGTYSNFFTDPAQIKGVVVFCAFLLSFFSLGNIGAAILLPILYGTDDTLGDFCIQSLIFGYYCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSI5</accession>
    <name>A4RSI5_OSTLU</name>
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        <recommendedName>
            <fullName evidence="4">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416202.1"/>
    </dbReference>
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        <property type="gene ID" value="OSTLU_30241"/>
    </dbReference>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20675" checksum="F8B161AAD76BF349" modified="2007-05-15" version="1">MSATHGACARAHDAANVPVLTLIALACVAGIAGALDPLVVTKGFLAYIVLDGLWIALWPRCVPSAAAVVVAHHVVTAALLAYPLRHPERAIETCRNGLVEANTLFLILRRRVRRGSAMHAVWNGLYVATLAPVRFAWQPYLLWHFYANVTKDDVWWEKVQVCGAQMFLIGFNVFLVARRRVAPAKKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSQ4</accession>
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        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Rpb9</name>
        <name evidence="11" type="ORF">OSTLU_119611</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 9">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO94742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416412.1"/>
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    <dbReference type="STRING" id="436017.A4RSQ4"/>
    <dbReference type="GeneID" id="5000101"/>
    <dbReference type="Gramene" id="ABO94742">
        <property type="protein sequence ID" value="ABO94742"/>
        <property type="gene ID" value="OSTLU_119611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119611"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:nucleic acid binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
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    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
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        <property type="entry name" value="Zn_ribbon_RPB9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 11" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2 7 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="10">
        <location>
            <begin position="81"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="124" mass="13901" checksum="E9E6492831F52CAC" modified="2007-05-15" version="1">MAGSDTHSGAVPLRFCPNSNDLLYPKEDRVNKKLVYFCRNCDYTIAATENCVHRRTIFHSASEITAVIHDVRTDPTLPRSKDVQCSLCDAREAVFFSQTTTEGMSLFFQCINCGNKWKDTGTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RST6</accession>
    <name>A4RST6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SRP54-type proteins GTP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">srrA</name>
        <name evidence="10" type="ORF">OSTLU_119580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416189.1">
        <property type="nucleotide sequence ID" value="XM_001416152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RST6"/>
    <dbReference type="STRING" id="436017.A4RST6"/>
    <dbReference type="GeneID" id="5000172"/>
    <dbReference type="Gramene" id="ABO94482">
        <property type="protein sequence ID" value="ABO94482"/>
        <property type="gene ID" value="OSTLU_119580"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119580"/>
    <dbReference type="eggNOG" id="KOG0781">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_8_2_1"/>
    <dbReference type="OMA" id="QQNFSVM"/>
    <dbReference type="OrthoDB" id="1727884at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17876">
        <property type="entry name" value="SRalpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000188">
        <property type="entry name" value="signal recognition particle receptor subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF1">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="9">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="131"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="525" mass="58477" checksum="382495A6E66EEE8A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT65</accession>
    <name>A4RT65_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_29976</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416126.1">
        <property type="nucleotide sequence ID" value="XM_001416089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT65"/>
    <dbReference type="STRING" id="436017.A4RT65"/>
    <dbReference type="GeneID" id="5000110"/>
    <dbReference type="Gramene" id="ABO94418">
        <property type="protein sequence ID" value="ABO94418"/>
        <property type="gene ID" value="OSTLU_29976"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29976"/>
    <dbReference type="eggNOG" id="KOG2260">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046495_0_0_1"/>
    <dbReference type="OMA" id="AEQCIII"/>
    <dbReference type="OrthoDB" id="440202at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013855">
        <property type="entry name" value="Cdc37_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03234">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01071">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 N-terminal" evidence="10">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="9">
        <location>
            <begin position="138"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="8">
        <location>
            <begin position="309"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="53"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="378" mass="42520" checksum="E9FE63BBDA49B906" modified="2007-05-15" version="1">MSTKPFDYSKWDAIELSDDEDSHPGAQFIEAQTLRRIKREAHEHKERERIARVDALKTKKKALKREIKSEEETLVRTVETLTPEADGNGDGDAARRAAETARATIEAKRTELADVERQIEALEHQKKFNAEEMCYVASEKTLVGAACKPEEVARAQTMSYEEYVKTYGEDLDEIASGNASMSYGELGEWFANGKLHLFCEHSTGYLLLKSLYLEMEKKTREARTCARVAFACKSIGEFAEAGKKSERDAAEPFFRRLDTNPDVAREYEKSFDEYFEKLRERAEVKLREEAASASAAEPTSLEEVPLEDRLGPGGLDPVAVYDALPREMREAFDSGSVDALKKFVNSLPMDEARAHMRAMVDSGLWVPTPGEDPGEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTQ2</accession>
    <name>A4RTQ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_30343</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416827.1">
        <property type="nucleotide sequence ID" value="XM_001416790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTQ2"/>
    <dbReference type="GeneID" id="5000972"/>
    <dbReference type="Gramene" id="ABO95120">
        <property type="protein sequence ID" value="ABO95120"/>
        <property type="gene ID" value="OSTLU_30343"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30343"/>
    <dbReference type="HOGENOM" id="CLU_750972_0_0_1"/>
    <dbReference type="OMA" id="CLDWLNM"/>
    <dbReference type="OrthoDB" id="10497828at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="165"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="165"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="209"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="369" mass="41336" checksum="9A7A9B51F707F366" modified="2007-05-15" version="1">MVAGVGKGKKNAFVALLGRAVRAEDDFARALVESSRDYASWAKLARARGRREGDAHADALRLLDSKGHLLNVLDRACEVEDGDDGAKDEVERARRVREAWTKTKATQRAKFEKSGGAEGVAEARLRKREAKERINASRKEREAREARDKERKEARLEYATKVHEARSAGACLDWLNMGRCRFGEECQFEHDAMSRGNLKDLAVKVGAETGDVKRERNQTEKAERKARAKAMREAGGGDDEDTLGGRFSSSEDESDDDEGDVPGFLKIERARRAAEALLATNKTSSSKTNKDAGKSATKKAKHFNEKQLERKQKFLKEGKNQPFVKKGMKKRPQPTESAQKNKKKKPRRADSERKQKRKGMARTFFGGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU21</accession>
    <name>A4RU21_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_14510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416595.1">
        <property type="nucleotide sequence ID" value="XM_001416558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU21"/>
    <dbReference type="STRING" id="436017.A4RU21"/>
    <dbReference type="GeneID" id="5001048"/>
    <dbReference type="Gramene" id="ABO94888">
        <property type="protein sequence ID" value="ABO94888"/>
        <property type="gene ID" value="OSTLU_14510"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14510"/>
    <dbReference type="eggNOG" id="ENOG502S0H6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079764_1_0_1"/>
    <dbReference type="OMA" id="VRHPMHV"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF40">
        <property type="entry name" value="FRUCTOSE-6-PHOSPHATE ALDOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="272" mass="29404" checksum="4CF8FA8AC973604B" modified="2007-05-15" version="1">MRASDAVEVAEDDYRGTLRLFLDTADEETFDAWLPTGMFVGVTTNPTILERDGVECSVDALSALARNALEFDAVEEFQVQTWGEDSDEMWKNGIALARLDPERVVVKVPVTLEGIKAANALVVDGVRVTMTAAYAPHQVLVAASIGANYIAPYLGRMNDAGRDGLGTIVSMQETVDELESDMRILVASVRTVAEMAKLAAKGCDTFTISEKVAAEMFTDPLTSQAAIDFQSCAERMAPKPPKKEKEAVVVEEIDVDDSDDTDIVQDSDASDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUB2</accession>
    <name>A4RUB2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_30560</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 22 family. PIGZ subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416929.1">
        <property type="nucleotide sequence ID" value="XM_001416892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUB2"/>
    <dbReference type="STRING" id="436017.A4RUB2"/>
    <dbReference type="CAZy" id="GT22">
        <property type="family name" value="Glycosyltransferase Family 22"/>
    </dbReference>
    <dbReference type="GeneID" id="5000774"/>
    <dbReference type="Gramene" id="ABO95222">
        <property type="protein sequence ID" value="ABO95222"/>
        <property type="gene ID" value="OSTLU_30560"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30560"/>
    <dbReference type="eggNOG" id="KOG4123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022957_2_0_1"/>
    <dbReference type="OMA" id="HGIHPRY"/>
    <dbReference type="OrthoDB" id="10066429at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF3">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671970" description="Mannosyltransferase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="551" mass="59940" checksum="933B9033A138BDF3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUC5</accession>
    <name>A4RUC5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_49228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416937.1">
        <property type="nucleotide sequence ID" value="XM_001416900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUC5"/>
    <dbReference type="STRING" id="436017.A4RUC5"/>
    <dbReference type="GeneID" id="5001056"/>
    <dbReference type="Gramene" id="ABO95230">
        <property type="protein sequence ID" value="ABO95230"/>
        <property type="gene ID" value="OSTLU_49228"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49228"/>
    <dbReference type="eggNOG" id="KOG1566">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035755_0_0_1"/>
    <dbReference type="OMA" id="YDWFFPE"/>
    <dbReference type="OrthoDB" id="609103at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="327" mass="37079" checksum="F0E36EB31F77D7C9" modified="2007-05-15" version="1">MFGKKVRTPEELVTKSHAALERLRVDRTSAKDVESVSKYFGEMRALLLSGDASAQQACETLVVKANACGLVAQIVSHLPHLPFETRKDAATVFNCIVRTSVRGHDVVVEDLSENPEVLEAIARGYENSDVALTFGAMLRDMCRNETLVRKILYGENFWKMFEYMQLETFEIASDAMATFREALTRHKDVAAEFLNANYERFVKAYTDLLEKGNYVTRRQALKLLGELLLDSANVTVMLKYVAEVENLCLMMNLMRDESKSIQFEAFHIFKVFVANPDKPASVAMILSKNKAKLITYLEDFQTTREDESFQSERSMLLSLLAELPDPE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-05" modified="2025-04-09" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUK2</accession>
    <name>RSSA_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Small ribosomal subunit protein uS2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">40S ribosomal protein SA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ORF">OSTLU_12355</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUK2"/>
    <dbReference type="SMR" id="A4RUK2"/>
    <dbReference type="STRING" id="436017.A4RUK2"/>
    <dbReference type="EnsemblPlants" id="ABO94979">
        <property type="protein sequence ID" value="ABO94979"/>
        <property type="gene ID" value="OSTLU_12355"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO94979">
        <property type="protein sequence ID" value="ABO94979"/>
        <property type="gene ID" value="OSTLU_12355"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12355"/>
    <dbReference type="eggNOG" id="KOG0830">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058171_0_1_1"/>
    <dbReference type="OMA" id="QCHLGAK"/>
    <dbReference type="OrthoDB" id="414863at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000017">
        <property type="entry name" value="40S ribosomal protein SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03015">
        <property type="entry name" value="Ribosomal_S2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032281">
        <property type="entry name" value="Ribosomal_uS2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027498">
        <property type="entry name" value="Ribosomal_uS2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_uS2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01012">
        <property type="entry name" value="uS2_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16122">
        <property type="entry name" value="40S_SA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000371601" description="Small ribosomal subunit protein uS2">
        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="290" mass="31323" checksum="4101E77C0B8BC6D2" modified="2007-05-15" version="1">MAPQMSQKEADIAMMLAAGCHLGTKNVDFQMERYVWKRRADGIHIINLGRTWDKLMLAARIIVACENPQDVICQAARPYGQRAVLKFAQYTGAKAIAGRHTPGTYTNQKDAIFAEPRVLIVTDPRTDAQPISETAYVNLPTIAFCDTDSPLKNVDVAIPANNKAKHSIGCLYYLLARMVLQMRGTVSAANPWDVMVDLFFYRDPEELEAKEEEAAAAAAAPAESAGYNAVADAAYGAESWDEQKPAEAFPTGGFAPAAGNWSEAPAPTGWDAQQGGDFGSGFGAMPPQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUP4</accession>
    <name>A4RUP4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-acyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_34299</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416708.1">
        <property type="nucleotide sequence ID" value="XM_001416671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUP4"/>
    <dbReference type="GeneID" id="5000586"/>
    <dbReference type="Gramene" id="ABO95001">
        <property type="protein sequence ID" value="ABO95001"/>
        <property type="gene ID" value="OSTLU_34299"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34299"/>
    <dbReference type="eggNOG" id="KOG1315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027721_7_0_1"/>
    <dbReference type="OMA" id="THRTQTN"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="101"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="300" mass="34172" checksum="2D9EA26E87E6B8EA" modified="2007-05-15" version="1">MNRRVRARTCARRCVGKLNLPVVLVLGMYSYVYETTKTYAFHEGRAGGLAELVFALTAGLGMVMYACTVLRDPGRVPGDYVPKVEEGDALVEAKRKGGGFRFCQKCERHKPPRTHHCRVCKRCVLRMDHHCVWVNNCVGHYNYKSFFLFLFYATISLCQAAYHLGNFAASEIFNPRGSKFDDYKASSLVIGCLVVTCTLTIALAALFVWHVRLVVNNKTTIEHYEGVRSRYNNIPTVVEHPYSLGLLANLREILGRNVLFWFTPGCKISGDGTRYPNVLEMSRERWDRTVRTKERELTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV35</accession>
    <name>A4RV35_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417068.1">
        <property type="nucleotide sequence ID" value="XM_001417031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV35"/>
    <dbReference type="GeneID" id="5000793"/>
    <dbReference type="Gramene" id="ABO95361">
        <property type="protein sequence ID" value="ABO95361"/>
        <property type="gene ID" value="OSTLU_14789"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14789"/>
    <dbReference type="HOGENOM" id="CLU_2007776_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="124" mass="13531" checksum="AF011C24107CEC24" modified="2007-05-15" version="1">MLFVVAAALMAVVAWMLVCLCRVKRAKTRAAAMEARAAAEARRRALEEKERAHEAWRGRCAAFAMPGGEVMIAIETRDDDDDDDDETIENGDDARARDAVTCVVTLREAGDDDDAKTTGDDTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVB5</accession>
    <name>A4RVB5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial</fullName>
            <ecNumber evidence="8">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="8">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_30915</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterooctamer of 4 alpha and 4 beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="8"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416813.1">
        <property type="nucleotide sequence ID" value="XM_001416776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVB5"/>
    <dbReference type="STRING" id="436017.A4RVB5"/>
    <dbReference type="GeneID" id="5000673"/>
    <dbReference type="Gramene" id="ABO95106">
        <property type="protein sequence ID" value="ABO95106"/>
        <property type="gene ID" value="OSTLU_30915"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30915"/>
    <dbReference type="eggNOG" id="KOG1255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052104_1_0_1"/>
    <dbReference type="OMA" id="MPGSIFR"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000005">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004230">
        <property type="entry name" value="PRK05678.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF2">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA-binding" evidence="11">
        <location>
            <begin position="52"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="8 9">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="65"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="144"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00061754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="344" mass="35955" checksum="59C54FD5FF521FB3" modified="2007-05-15" version="1">MRRTSIKSLIERASAASAASAVARAARAAFTSSSTASVRASSSSHADSPAVFVDKNTRVIVQGFTGKNGTFHSEQAIAYGTQVVGGVTPRKGGTTHLNLPVFDTVREAKESTKANASVIYVPPPFAARAVMEAIEAEVELVVCITEGIPQHDMVRVKQALMSQSKTRLIGPNCPGIIKPGECKIGIMPGYIHKPGRVGVVSRSGTLTYEAVYQTTVAGLGQSTCVGIGGDPFNGTNFVDCLEKFVKDPQTEGIIMIGEIGGTAEEEAAEFIRASGTEKPIVSFIAGLTAPPGRRMGHAGAIISGGKGSAGDKIAALERVGVRVVKSPAKMGQAMYEMFGERNML</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVI7</accession>
    <name>A4RVI7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_37043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417426.1">
        <property type="nucleotide sequence ID" value="XM_001417389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVI7"/>
    <dbReference type="STRING" id="436017.A4RVI7"/>
    <dbReference type="GeneID" id="5001149"/>
    <dbReference type="Gramene" id="ABO95719">
        <property type="protein sequence ID" value="ABO95719"/>
        <property type="gene ID" value="OSTLU_37043"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37043"/>
    <dbReference type="eggNOG" id="KOG3063">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031077_2_0_1"/>
    <dbReference type="OMA" id="GQNTFNE"/>
    <dbReference type="OrthoDB" id="3821113at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000015">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="34097" checksum="CE99EA77FD5BD4CA" modified="2007-05-15" version="1">MSFLGFGKVCTVDLTHDAGDAQPMVSVKNEQGTAHEHLPLFSTGQTIVGKVHVAPIPGKKFEHRGVRVELIGQIERYGDRSVVDFLASTRDLEPPGELSAPKSLGFEFKHVEMQHESYHGINVRLRYFLRVVVSRSYASGVAQEFKFWVQNPVPAVPEMNNSIRMEVGIEDCLHIEFEYARAKYSLKDVVVGKIYFLLVKIKIKHMELEIRRRESTEGGASAHNESETIAKYEVMDGAPVRGESIPVRLFLSPYDLTPTYKNVNNRFSVKYYLNLVLVDEWDRRYFKQQEITLYRAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVS4</accession>
    <name>A4RVS4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417198.1">
        <property type="nucleotide sequence ID" value="XM_001417161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVS4"/>
    <dbReference type="GeneID" id="5001625"/>
    <dbReference type="Gramene" id="ABO95491">
        <property type="protein sequence ID" value="ABO95491"/>
        <property type="gene ID" value="OSTLU_14960"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14960"/>
    <dbReference type="HOGENOM" id="CLU_1811203_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="143" mass="13713" checksum="B61878F072BCA2D7" modified="2007-05-15" version="1" fragment="single">MADEGDAAKPRLDASAASFNFNPSASAFEFKPRTVTPVAGDDGRGPTPPPGAPPAKAASLSIGGPAKAVTIGGPAKAVTIGGPAKAVSLSIGGPAKAVTIGGPAKAKASEDDAEGDEAAAAASAAKVEKVAAKVAEVVIEDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWC7</accession>
    <name>A4RWC7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Right handed beta helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417305.1">
        <property type="nucleotide sequence ID" value="XM_001417268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWC7"/>
    <dbReference type="STRING" id="436017.A4RWC7"/>
    <dbReference type="GeneID" id="5001355"/>
    <dbReference type="Gramene" id="ABO95598">
        <property type="protein sequence ID" value="ABO95598"/>
        <property type="gene ID" value="OSTLU_15121"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15121"/>
    <dbReference type="eggNOG" id="ENOG502RRFX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_566717_0_0_1"/>
    <dbReference type="OMA" id="VMSKCVV"/>
    <dbReference type="OrthoDB" id="626167at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051550">
        <property type="entry name" value="SCF-Subunits/Alg-Epimerases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22990">
        <property type="entry name" value="F-BOX ONLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22990:SF15">
        <property type="entry name" value="F-BOX ONLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Right handed beta helix" evidence="2">
        <location>
            <begin position="256"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="482" mass="51593" checksum="E803671618F4F7D4" modified="2007-05-15" version="1">MKCGDFALAQALYGEALDAAREEDAHLRAVVFCNRALAFHKMNEYDAALCDAKCAEELAPTWSKPKHRLAEACLRLGSYTLAVTYARLGEKLQFEEGDFSKSFRDVLDEIAICAAEDGSVAGFDGKLIYVRSAGEDAWLGREAPLNAAFDELEGEVADPMFGGGSAKDANSMKPVHARSLPEAISKANDGDRILLLRGVHNGLGTVVEIDKRVLIRGEGALRDTTCDCRNNAALFRIKRPCVIQNLDIDFTGFSEAIRIKGDSRVNALIENCVIRSSGGDCVAVGGKSAPTFRNCSITGKLSGVRSYAQATPTFIDCNITRSGLQGVLAMKESRVIMHGCAVQNNEEDGVVVMEQSNVVMSKCVVQDNKGPGVDVSNTAKVVVNDCDIDANVGGLWLWDHSCAHVAASSVNGGKSHAVLVDVNARANCRRTKIIGVVHASETGARGVRGEGTVVETLETPTSLPQEAKGAFKHDPCGFSRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWE2</accession>
    <name>A4RWE2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_49504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417563.1">
        <property type="nucleotide sequence ID" value="XM_001417526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWE2"/>
    <dbReference type="STRING" id="436017.A4RWE2"/>
    <dbReference type="GeneID" id="5001621"/>
    <dbReference type="Gramene" id="ABO95856">
        <property type="protein sequence ID" value="ABO95856"/>
        <property type="gene ID" value="OSTLU_49504"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49504"/>
    <dbReference type="eggNOG" id="KOG2620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_5_1_1"/>
    <dbReference type="OMA" id="EMMMMTQ"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd03407">
        <property type="entry name" value="SPFH_like_u4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF31">
        <property type="entry name" value="HYPERSENSITIVE-INDUCED RESPONSE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="1">
        <location>
            <begin position="9"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="32292" checksum="29198B0A2C61FB5F" modified="2007-05-15" version="1">MTAGPTGCCCFTCVPTGTVQVIQQCGKFAFFAREGCHFVNPFIGQAVAGTVSTRVQSLDVSVETKTKDNVFVTIVVSTQYQVLSMDETRLYDAFYKLTDSKAQIRSYVFDVVRSTVPRIKLDDVFESKEEIAQSVKELLSKSMEGFGYQIMNTLVTDIAPDARVKQAMNEINAAQRARVAAQDRAEADKIMVVKAAEADAESKYLAGTGMARQRQAIIAGLRESVVDFQESVDGISSKDVLEMMMMTQYFDTMKEVGTQGGNSTIFVPSGPGAVAEASRDIRMGLMQGQAAQIGRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWQ8</accession>
    <name>A4RWQ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_9237</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417371.1">
        <property type="nucleotide sequence ID" value="XM_001417334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWQ8"/>
    <dbReference type="STRING" id="436017.A4RWQ8"/>
    <dbReference type="GeneID" id="5001575"/>
    <dbReference type="Gramene" id="ABO95664">
        <property type="protein sequence ID" value="ABO95664"/>
        <property type="gene ID" value="OSTLU_9237"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9237"/>
    <dbReference type="HOGENOM" id="CLU_159623_2_2_1"/>
    <dbReference type="OMA" id="QQSAHMW"/>
    <dbReference type="OrthoDB" id="550883at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050913">
        <property type="entry name" value="AP2/ERF_ERF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31194:SF140">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR CRF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31194">
        <property type="entry name" value="SHN SHINE , DNA BINDING / TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038123">
        <property type="entry name" value="PTI6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="20"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="76" mass="8573" checksum="08CC7E1939627529" modified="2007-05-15" version="1" fragment="single">RRRTQGGKGDKQSKKATTSQYRGVRQRPWGSWAAEIRDPNRGARLWLGTFDTAEEAARAYDAAARHIRGPNAKTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWR0</accession>
    <name>A4RWR0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S17, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS17</name>
        <name evidence="5" type="ORF">OSTLU_31424</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417372.1">
        <property type="nucleotide sequence ID" value="XM_001417335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWR0"/>
    <dbReference type="STRING" id="436017.A4RWR0"/>
    <dbReference type="GeneID" id="5001576"/>
    <dbReference type="Gramene" id="ABO95665">
        <property type="protein sequence ID" value="ABO95665"/>
        <property type="gene ID" value="OSTLU_31424"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31424"/>
    <dbReference type="eggNOG" id="KOG0187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112958_2_0_1"/>
    <dbReference type="OMA" id="DSHANKC"/>
    <dbReference type="OrthoDB" id="1727351at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.60.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="entry name" value="Ribosomal protein S17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_eS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_eS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018273">
        <property type="entry name" value="Ribosomal_eS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="Ribosomal_eS17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="Rps17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00712">
        <property type="entry name" value="RIBOSOMAL_S17E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="134" mass="15523" checksum="F276F2D973030352" modified="2007-05-15" version="1">MGRVRTKTVKKASRQIIEKYYSRLTLDFATNKRIADDIAIIPSKRLRNKIAGFTTHLMKRIQRGPVRGISLKLQEEERERRMDFVPEKSALETDSIEVDRDTMDMLKSMNMGNLQGVSVSSRAHYNKGPRRDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWT3</accession>
    <name>A4RWT3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417387.1">
        <property type="nucleotide sequence ID" value="XM_001417350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWT3"/>
    <dbReference type="GeneID" id="5001652"/>
    <dbReference type="Gramene" id="ABO95680">
        <property type="protein sequence ID" value="ABO95680"/>
        <property type="gene ID" value="OSTLU_31448"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31448"/>
    <dbReference type="eggNOG" id="KOG1981">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006472_1_0_1"/>
    <dbReference type="OMA" id="VHCTFRG"/>
    <dbReference type="OrthoDB" id="276323at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="726" mass="80706" checksum="EB187F5CB6EB8E00" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX97</accession>
    <name>A4RX97_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CNNM transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_49610</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417715.1">
        <property type="nucleotide sequence ID" value="XM_001417678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX97"/>
    <dbReference type="STRING" id="436017.A4RX97"/>
    <dbReference type="GeneID" id="5002031"/>
    <dbReference type="Gramene" id="ABO96008">
        <property type="protein sequence ID" value="ABO96008"/>
        <property type="gene ID" value="OSTLU_49610"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49610"/>
    <dbReference type="eggNOG" id="KOG2118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011310_1_3_1"/>
    <dbReference type="OMA" id="KLMFMHA"/>
    <dbReference type="OrthoDB" id="5353557at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010960">
        <property type="term" value="P:magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF94">
        <property type="entry name" value="UNEXTENDED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25562">
        <property type="entry name" value="CNBH_CNNM2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="8">
        <location>
            <begin position="35"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="470"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="62878" checksum="C0537497F4610499" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXA4</accession>
    <name>A4RXA4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417964.1">
        <property type="nucleotide sequence ID" value="XM_001417927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXA4"/>
    <dbReference type="GeneID" id="5001703"/>
    <dbReference type="Gramene" id="ABO96257">
        <property type="protein sequence ID" value="ABO96257"/>
        <property type="gene ID" value="OSTLU_92731"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92731"/>
    <dbReference type="HOGENOM" id="CLU_1557821_0_0_1"/>
    <dbReference type="OMA" id="CERESNG"/>
    <dbReference type="OrthoDB" id="10445072at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="172" mass="18448" checksum="4853B081F79C6637" modified="2007-05-15" version="1">MTDAKSTTRTRAPDALDMRKGVEERDPTYAEATARARALGRTTARDFRGFHRCRGGTGDECGGACRAVCRACPICAYNVSCGDGCTDAIWCWCGVPVPALSCVTAFALDEDDGSGAFVARDKQRQKSCAFVPLDRETGRYAVYVAHCRGCGTEFRDDSEPACVAEVWPLAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXD8</accession>
    <name>A4RXD8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protease Do-like PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_31659</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417982.1">
        <property type="nucleotide sequence ID" value="XM_001417945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXD8"/>
    <dbReference type="STRING" id="436017.A4RXD8"/>
    <dbReference type="MEROPS" id="S01.A05"/>
    <dbReference type="GeneID" id="5001915"/>
    <dbReference type="Gramene" id="ABO96275">
        <property type="protein sequence ID" value="ABO96275"/>
        <property type="gene ID" value="OSTLU_31659"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31659"/>
    <dbReference type="eggNOG" id="KOG1320">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_10_0_1"/>
    <dbReference type="OMA" id="HCEPNYS"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000012">
        <property type="entry name" value="protease Do-like 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041517">
        <property type="entry name" value="DEGP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046449">
        <property type="entry name" value="DEGP_PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45980:SF18">
        <property type="entry name" value="PROTEASE DO-LIKE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17815">
        <property type="entry name" value="PDZ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Protease Do-like PDZ" evidence="6">
        <location>
            <begin position="403"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="550" mass="60196" checksum="9E068F1CDDC80D6E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXS0</accession>
    <name>A4RXS0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyanocobalamin reductase (cyanide-eliminating)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417804.1">
        <property type="nucleotide sequence ID" value="XM_001417767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXS0"/>
    <dbReference type="GeneID" id="5001776"/>
    <dbReference type="Gramene" id="ABO96097">
        <property type="protein sequence ID" value="ABO96097"/>
        <property type="gene ID" value="OSTLU_31792"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31792"/>
    <dbReference type="eggNOG" id="ENOG502S75U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073720_1_0_1"/>
    <dbReference type="OMA" id="PWCAFRA"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="29061" checksum="D323D6CE2267575A" modified="2007-05-15" version="1">MENIDAVEVVETLARACAARGLDVVAACSAADYDAAAPETARIGAREDGRATSPLVALIGNSKALWPAFADALARDGTMTLDEYCERVVRDAAADAIEVARGFKRRSGEDSSSRVRIFWASDVEEGKVIAIQRLAHVANCAWLDENTHQSIHPLHGPWCAFRAAVVFDDVEEPDEEDLQPKIEKCPVSDETLANAKAAFDVAVERFNATDGKDPEQWRLWLAARDAMGGGAFAKERYYEDQILWHYDVDREGVRKRLARGVKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXW7</accession>
    <name>A4RXW7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RimM N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_38467</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418069.1">
        <property type="nucleotide sequence ID" value="XM_001418032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXW7"/>
    <dbReference type="STRING" id="436017.A4RXW7"/>
    <dbReference type="GeneID" id="5001953"/>
    <dbReference type="Gramene" id="ABO96362">
        <property type="protein sequence ID" value="ABO96362"/>
        <property type="gene ID" value="OSTLU_38467"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38467"/>
    <dbReference type="eggNOG" id="KOG2388">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077636_3_0_1"/>
    <dbReference type="OMA" id="TDFSEHR"/>
    <dbReference type="OrthoDB" id="532420at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.240">
        <property type="entry name" value="PRC-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33692">
        <property type="entry name" value="RIBOSOME MATURATION FACTOR RIMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33692:SF1">
        <property type="entry name" value="RIBOSOME MATURATION FACTOR RIMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="PRC-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="RimM N-terminal" evidence="6">
        <location>
            <begin position="12"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="PRC-barrel" evidence="7">
        <location>
            <begin position="117"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="25529" checksum="4598CE751A440945" modified="2007-05-15" version="1">MDDASASESLIQVGAIVGAHSLRGEVRVKPMTDFIEERLMRTGSTLRFDAPPGEVRAVKVRSGRWVTSKGRNDVIVKLAGCDDRNAAEALVGTRLFVLPSDREPLRKDEGAEGSDGDDEFYAQELEGLRVVERDTGEVIGVVEDVVRGAGTQDLLKVAFIALDEETGIDAEYYVYVPFVKEIVPLVDATNGFMEITPPGGLLDLKIPKKTKKQRARVAAKQKEKRDAAAEASADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYP1</accession>
    <name>A4RYP1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_41102</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418427.1">
        <property type="nucleotide sequence ID" value="XM_001418390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYP1"/>
    <dbReference type="STRING" id="436017.A4RYP1"/>
    <dbReference type="GeneID" id="5002559"/>
    <dbReference type="Gramene" id="ABO96720">
        <property type="protein sequence ID" value="ABO96720"/>
        <property type="gene ID" value="OSTLU_41102"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41102"/>
    <dbReference type="eggNOG" id="KOG0595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="MEACEPY"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14009">
        <property type="entry name" value="STKc_ATG1_ULK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="38"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="33648" checksum="5D79DF412A42BBC3" modified="2007-05-15" version="1" fragment="single">MTRTTDGTRGVADASREGWTTRARGASGRRRTVGERWALDDATLGRGSFATVWRATCVKTGAVVAVKEIACERLSKKLRESLKLEVEVMRRMRDENILRFIDMQSSNETVYIVLEYCGGGDLSQFIKRHGRMEEIAARRFMLQLARGLKAMRKAQIVHRDLKPQNLLLTSNDLNAELKIADFGFARYIRDSEGMADTVCGSPLYMAPEVLNYQRYDAKADLWSVGAILFEMLVGTVPFTGQNQVQLLRNIQKTEFKIPIHIAQGLSAECIDLLRGLLHRDAANRISFEEFFNHPFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZA7</accession>
    <name>A4RZA7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_32317</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418298.1">
        <property type="nucleotide sequence ID" value="XM_001418261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZA7"/>
    <dbReference type="GeneID" id="5002178"/>
    <dbReference type="Gramene" id="ABO96591">
        <property type="protein sequence ID" value="ABO96591"/>
        <property type="gene ID" value="OSTLU_32317"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32317"/>
    <dbReference type="HOGENOM" id="CLU_913343_0_0_1"/>
    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="8"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="126"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="206"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="58"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="276"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="33597" checksum="35E93F244161787B" modified="2007-05-15" version="1">MNTRGNNGLVVGPQGSNVKRIEDETGARVKCLKDKTTVEIYGSPEAVRRATDKIIDLLEAKSGGSRDRPGEKRRRDDDRFGDDNKRPRGAQNDSLLDYLRSSAVELGVSKEFPPDFVDESNADEQGNVEETASITNYVGLIIGKQGRMHSEIQRIVDIPMTINKEDETVTFKGPAANVGRGLALIREVIELTNAVRDARNATRERDDVEETISITGNVGAVVGKQGNTVKRIKSQLPRCLFQVDRNSETVLVRGAPEMVELAKRLVSEAIENVQARARERGGDVDADMGGEAPMEQDRDLRERLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZJ9</accession>
    <name>A4RZJ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418809.1">
        <property type="nucleotide sequence ID" value="XM_001418772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZJ9"/>
    <dbReference type="STRING" id="436017.A4RZJ9"/>
    <dbReference type="GeneID" id="5003067"/>
    <dbReference type="Gramene" id="ABO97102">
        <property type="protein sequence ID" value="ABO97102"/>
        <property type="gene ID" value="OSTLU_92960"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92960"/>
    <dbReference type="HOGENOM" id="CLU_995132_0_0_1"/>
    <dbReference type="OMA" id="YDEWRVP"/>
    <dbReference type="OrthoDB" id="496335at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043186">
        <property type="entry name" value="Str14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44920:SF2">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44920">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 14, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="56"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="241" mass="25739" checksum="9126311A102B2266" modified="2007-05-15" version="1">MARATTTRASTSTSASSVIPGKGPGSPKYGEIYETLVKSKKVRAATANEVAEMLSGKRRGVVVDVRQPLEHAEWRLVGTKSAPYLVPMENVLRRASGYFLAIKGGLKERNVAFVDVVAEVTKNRRDAVVLVDLRGGDLDIAPLNGSTAVSDRGDSLSLRAAYELVQAGYTDVRYVPGGFPALIDEGGLEYESEKYAGLLDAVGEGARKTLMYSNLLPDPSLAPGFVVQIVLLAALAFLQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZL2</accession>
    <name>A4RZL2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418814.1">
        <property type="nucleotide sequence ID" value="XM_001418777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZL2"/>
    <dbReference type="GeneID" id="5003075"/>
    <dbReference type="Gramene" id="ABO97107">
        <property type="protein sequence ID" value="ABO97107"/>
        <property type="gene ID" value="OSTLU_24745"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24745"/>
    <dbReference type="HOGENOM" id="CLU_520146_0_0_1"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="63"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="524" mass="58288" checksum="9D009A6F1346BE99" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZV4</accession>
    <name>A4RZV4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418635.1">
        <property type="nucleotide sequence ID" value="XM_001418598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZV4"/>
    <dbReference type="GeneID" id="5002950"/>
    <dbReference type="Gramene" id="ABO96928">
        <property type="protein sequence ID" value="ABO96928"/>
        <property type="gene ID" value="OSTLU_32521"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32521"/>
    <dbReference type="HOGENOM" id="CLU_2562513_0_0_1"/>
    <dbReference type="OMA" id="TKSAMRQ"/>
    <dbReference type="OrthoDB" id="498423at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="82" mass="8613" checksum="73454A221CDE67D0" modified="2007-05-15" version="1">MGARDADAACALRDDEVSNALFELTALAGLDVRREVHDAVLELSRARVVPTATAQVLRSLASKAADARAAGLEDALRAPARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZW2</accession>
    <name>A4RZW2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_4907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418638.1">
        <property type="nucleotide sequence ID" value="XM_001418601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZW2"/>
    <dbReference type="STRING" id="436017.A4RZW2"/>
    <dbReference type="GeneID" id="5002955"/>
    <dbReference type="Gramene" id="ABO96931">
        <property type="protein sequence ID" value="ABO96931"/>
        <property type="gene ID" value="OSTLU_4907"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4907"/>
    <dbReference type="eggNOG" id="ENOG502QPQG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1263165_0_0_1"/>
    <dbReference type="OMA" id="DFECDIR"/>
    <dbReference type="OrthoDB" id="10017101at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF99">
        <property type="entry name" value="OS06G0646000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="50"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="227" mass="25276" checksum="B4E174D7A61BE283" modified="2007-05-15" version="1" fragment="single">TATFETPQVAFAYERGWRDSFKRAGFPGPDEEARLAVDALGEFAKGGIVVDASCGSGLFTRRFLKTYKGRSKAYKGVVALDYSDAMLRQAKQYMEDENLLGDADVCFVRADIARLPFPEGSLDGVHAGAAIHCWPDAKTGVAEIARVLKPGATFCGTTFMNPQVPFFDEDQQAIFDNAVREFSGTVNAERGFRWWSKKELRDLCTECGLVDFKCEIRNQFIFYSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZW5</accession>
    <name>A4RZW5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CLASP N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418870.1">
        <property type="nucleotide sequence ID" value="XM_001418833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZW5"/>
    <dbReference type="GeneID" id="5002661"/>
    <dbReference type="KEGG" id="olu:OSTLU_92998"/>
    <dbReference type="HOGENOM" id="CLU_1492752_0_0_1"/>
    <dbReference type="OMA" id="MXRTSSP"/>
    <dbReference type="OrthoDB" id="10456668at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CLASP N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="19717" checksum="C32EEF6FFEEB9597" modified="2007-05-15" version="1" fragment="single">LRPFIIGVTSCLESLRSSISKAALSLIKTLAVHLKGKINGELGCVFPSVLKRASESSFLSAEADEVLHVLIEAAAPHAVIRTLSQHVSARRLQAKIAFALTYCVERNAECASVFRGRAGRTALDLTLATLDVCIRGGHPDARLYAKRCLSCLIDVLGSDGLEKPMRAYPDLFAFEESGNASVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZZ5</accession>
    <name>A4RZZ5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418884.1">
        <property type="nucleotide sequence ID" value="XM_001418847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZZ5"/>
    <dbReference type="GeneID" id="5002865"/>
    <dbReference type="Gramene" id="ABO97177">
        <property type="protein sequence ID" value="ABO97177"/>
        <property type="gene ID" value="OSTLU_32565"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32565"/>
    <dbReference type="HOGENOM" id="CLU_3035773_0_0_1"/>
    <dbReference type="OrthoDB" id="74240at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="55" mass="5728" checksum="D1D0DA76E18343AB" modified="2007-05-15" version="1">MVNRLLLTGRDAVDQAVSKFLERREAIQREEDGGDGKGSVGGSFGGSLGGSVYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0V9</accession>
    <name>A4S0V9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419256.1">
        <property type="nucleotide sequence ID" value="XM_001419219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0V9"/>
    <dbReference type="GeneID" id="5003423"/>
    <dbReference type="Gramene" id="ABO97549">
        <property type="protein sequence ID" value="ABO97549"/>
        <property type="gene ID" value="OSTLU_93096"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93096"/>
    <dbReference type="HOGENOM" id="CLU_827399_0_0_1"/>
    <dbReference type="OMA" id="KDAVHAN"/>
    <dbReference type="OrthoDB" id="568363at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="36542" checksum="5BEE72DD3CBAA03B" modified="2007-05-15" version="1">MTRATILSATDDDDGGATASATATTRDDDDDDDRVSDADDRASRATEEAREDDDDEDANRLGRAREDDEGASSVVDANDDARARALADALSAERATRQGLEAAMESREVAHATERETLEARARDAEAGRVAAEAEASHLRGEIARGETVIRQEESVIRLRLEAEHEVRVGRLATELDRVRGELEARSSELRDARANDAKTFDALNRVREELLGRLKSETQKLLGTIDCVCDAMDSASKSLHRDGVAATPRISQSVPSRRERTLVVDTKQSRGHGAVGTPEPGTPMSSQSRHRAVASSSVAQQNAQRRLHLSAQSDRLRKPIASQKGLVGYANIYQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0W5</accession>
    <name>A4S0W5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U6 snRNA-associated Sm-like protein LSm8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM8</name>
        <name evidence="11" type="ORF">OSTLU_32889</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419048.1">
        <property type="nucleotide sequence ID" value="XM_001419011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0W5"/>
    <dbReference type="STRING" id="436017.A4S0W5"/>
    <dbReference type="GeneID" id="5003382"/>
    <dbReference type="Gramene" id="ABO97341">
        <property type="protein sequence ID" value="ABO97341"/>
        <property type="gene ID" value="OSTLU_32889"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32889"/>
    <dbReference type="eggNOG" id="KOG1784">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_8_1_1"/>
    <dbReference type="OMA" id="AACDQTT"/>
    <dbReference type="OrthoDB" id="10263346at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000084">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="97" mass="10504" checksum="2DABFFAE141F7D8D" modified="2007-05-15" version="1">MSAPTLTNMLDARVSVITNDGRHIVGTLRGFDQVTNVILEDCAERVYSSESGVEEAPLGVYMIRGDNVALVGPVDEELDAELDLSETRAPPLKAIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Y5</accession>
    <name>A4S0Y5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UPF3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_32910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419270.1">
        <property type="nucleotide sequence ID" value="XM_001419233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Y5"/>
    <dbReference type="STRING" id="436017.A4S0Y5"/>
    <dbReference type="GeneID" id="5003393"/>
    <dbReference type="Gramene" id="ABO97563">
        <property type="protein sequence ID" value="ABO97563"/>
        <property type="gene ID" value="OSTLU_32910"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32910"/>
    <dbReference type="eggNOG" id="ENOG502R8RU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_856319_0_0_1"/>
    <dbReference type="OMA" id="TIPRDDA"/>
    <dbReference type="OrthoDB" id="10645475at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF3" evidence="4">
        <location>
            <begin position="41"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="237"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="35437" checksum="2DD7564C5FDE1983" modified="2007-05-15" version="1">MDAPARARRPGRGRGRGRPGRGRGRRGGTTIPRDDARETRERRKIVIRNLPATLAREALEEALRRDGFGALDETFEWWEYARGKARGGTGGATTTTTRRATTPSRFYATVRRGETVKALRERYDGATFRVRARDEEGRAIEGGGGEETRARVEYAPSQWTPREFGERYATAGETAPAENALEGTIEEDEDYLKFLGALEAKKKANGATTGAATPKNAESAPRKSTALLEFLWRQRAAAEREKGAGKKSSKKSSKKSGKASQSKTGAKTAAPAAPKTESKKKKKTKTPKPKQTAAPNPSARANESKKTPEIKIIKRASMPVPKAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S150</accession>
    <name>A4S150_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_42708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO97592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4S150"/>
    <dbReference type="GeneID" id="5003376"/>
    <dbReference type="Gramene" id="ABO97592">
        <property type="protein sequence ID" value="ABO97592"/>
        <property type="gene ID" value="OSTLU_42708"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42708"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_18_1_1"/>
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    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="42"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="182" mass="18640" checksum="58B53FC49CA7BE92" modified="2007-05-15" version="1">MGINDHDTFTGLAPLHKAAADGDLEKVIALLDDGADGNIRANAGKTAAMFAASGGHVDVLKAMQRGPSLLDLTAEDGGTPAMSAAAHGFGDVLQLIIDKKCNLNAQDEDGWTALMYAVCAGNVENVARLVAAGADVKIKNKDGDDAKKLATGKNKDKLLAALRGKLDSIGEGKGGKKGCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S180</accession>
    <name>A4S180_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="5003409"/>
    <dbReference type="Gramene" id="ABO97395">
        <property type="protein sequence ID" value="ABO97395"/>
        <property type="gene ID" value="OSTLU_24915"/>
    </dbReference>
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    <dbReference type="OMA" id="LGCINVF"/>
    <dbReference type="OrthoDB" id="10576934at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="641" mass="66068" checksum="CDE60322D0428137" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1D6</accession>
    <name>A4S1D6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1D6"/>
    <dbReference type="GeneID" id="5003093"/>
    <dbReference type="Gramene" id="ABO97424">
        <property type="protein sequence ID" value="ABO97424"/>
        <property type="gene ID" value="OSTLU_16447"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16447"/>
    <dbReference type="eggNOG" id="ENOG502QVWK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF3">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
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        <location>
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            <end position="218"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
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        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO97424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="54332" checksum="9C3539CC4C8BFD57" modified="2007-05-15" version="1">MPHAAAARARAPARCGRRGPGAVRRARARASAGAASTSVVEGVVTRVARMGKRLTFVDVRAREQLRTRDGEETSTVFVKCAAQVPPVIRPGAVVEFEYEWETRRAKSGTRSGAYVSTTEMRVVELAPVTSVANATSEMLEKFAGVGLIDTTARRSKGFGICKVLLGGDVCSDPNCDKRHDVNEEELSQARESRKRARERSKMAIERERSDNDPHGDANKEAKCVSDRLFAEWCVETFKLKERREVVVADIAGGAGALSFEFHVNHGVGVVLIEPRCVALTPRQRATAKNLRRRGARNDANPDVADAWLRSEIWVKCADEQNEKRMHEHVQRLVAYTEIASSKDINVSASAPPTDVVTLHEAPFDEFPTELPRTVVKSPFGAEIAPFTHIRSEFWTTDSSVGARLREMRPSLLVGMHSDQATEAIIDAALELDVPFAVVPCCTFPELFPHRRTALGGPVASYADFIEYLRGKHPSIRSTFLPFKGRNQVLYKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1S1</accession>
    <name>A4S1S1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_88075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419196.1">
        <property type="nucleotide sequence ID" value="XM_001419159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1S1"/>
    <dbReference type="GeneID" id="5003195"/>
    <dbReference type="Gramene" id="ABO97489">
        <property type="protein sequence ID" value="ABO97489"/>
        <property type="gene ID" value="OSTLU_88075"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88075"/>
    <dbReference type="eggNOG" id="KOG2383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008681_0_1_1"/>
    <dbReference type="OMA" id="THNENEA"/>
    <dbReference type="OrthoDB" id="548867at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040713">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF6">
        <property type="entry name" value="AFG1-LIKE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="462" mass="50978" checksum="938DFB7C57F69204" modified="2007-05-15" version="1">MSRASSRVAPALARRARAATRDARGATTTTRDDDATRRRRRATTEARDDGQRRALDALERFYDGARLGTRAGRGVYLHGGVGRGKTALADATSEDAREKGGLEVERTHFHAFMARIHRALHESAMKARGEGGGGADDPLWTLGKNMATKTRQHVLCLDEMEISDVADAMVIERLMRSYFAHGGALVTTSNCAPERLYYGGINRAAFAGFADGLRARCEVVDLDARESVDYRRRARDEDVEDGVIFVGDDDATRERLSRAWDRFTRDAEGEREVDADVGRLRAKARVGAHARFTFDDICGRRSRAAPSDYVALAERFKVICVEDVPRLPVDASENEARRFINLIDVLYEHRVVLLANLWTSPDDLFDVVDGAVDDSDAFRELAPRERTRIENAFQSTLSVTRDGGSSGRSTTMLAPELEWSATGRVGASLAHVSGVNFTLAASPRAASRLHHMRSSAYFNTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1U7</accession>
    <name>A4S1U7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUS-like FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_4136</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419429.1">
        <property type="nucleotide sequence ID" value="XM_001419392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1U7"/>
    <dbReference type="GeneID" id="5003125"/>
    <dbReference type="Gramene" id="ABO97722">
        <property type="protein sequence ID" value="ABO97722"/>
        <property type="gene ID" value="OSTLU_4136"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4136"/>
    <dbReference type="eggNOG" id="KOG2335">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_2_1_1"/>
    <dbReference type="OMA" id="NNMIGAC"/>
    <dbReference type="OrthoDB" id="10262250at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004653">
        <property type="entry name" value="DusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008774">
        <property type="entry name" value="PRK11815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907">
        <property type="entry name" value="FMN-LINKED OXIDOREDUCTASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907:SF1">
        <property type="entry name" value="FMN-LINKED OXIDOREDUCTASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 10" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="11">
        <location>
            <begin position="4"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="6"/>
            <end position="8"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="355" mass="38803" checksum="FBA9EA376092B05B" modified="2007-05-15" version="1" fragment="single">ALSVAPMMEYTTPHFRVMARLMSRRVMLWTEMEVDQTVTHSARDGDRVDKFLDYPAATFGTVLQLGGSTPEYLGRATAIAAPYGYDEINLNSGCPSPKVAGKGCFGAALMAEPGLVAECLAAMAENAPEGTPVSVKCRIGVDDVDSYDDLCDYVERIVAGSSTRRFYVHARKALLAGLSPAENRTVPPLKHEWAYALARDFPECEFHLNGGLKTLNDVKNVLKRGPEDGGPIVGAMIGRQAHADPWGLLSAADTTLFGEASNPSASRRDFLNKYAVYADETIGRYGTAKDGYRIPSVRHMMHPIQNLFHGCANNKAWRRLVEEDLQKRSKHPDTTVRSVLDATLIAISDEDLDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1X7</accession>
    <name>A4S1X7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_956</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419443.1">
        <property type="nucleotide sequence ID" value="XM_001419406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1X7"/>
    <dbReference type="STRING" id="436017.A4S1X7"/>
    <dbReference type="CAZy" id="GH31">
        <property type="family name" value="Glycoside Hydrolase Family 31"/>
    </dbReference>
    <dbReference type="GeneID" id="5003488"/>
    <dbReference type="Gramene" id="ABO97736">
        <property type="protein sequence ID" value="ABO97736"/>
        <property type="gene ID" value="OSTLU_956"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_956"/>
    <dbReference type="eggNOG" id="KOG1066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017110_0_0_1"/>
    <dbReference type="OMA" id="HIWTGKQ"/>
    <dbReference type="OrthoDB" id="10070917at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052990">
        <property type="entry name" value="Sulfoquinovosidase_GH31"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007746">
        <property type="entry name" value="PRK10426.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46959">
        <property type="entry name" value="SULFOQUINOVOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46959:SF2">
        <property type="entry name" value="SULFOQUINOVOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="4">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="3">
        <location>
            <begin position="141"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="5">
        <location>
            <begin position="481"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="577" mass="64518" checksum="503991001BB9A96A" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Z4</accession>
    <name>A4S1Z4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cwf15/Cwc15 cell cycle control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_33271</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419234.1">
        <property type="nucleotide sequence ID" value="XM_001419197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Z4"/>
    <dbReference type="STRING" id="436017.A4S1Z4"/>
    <dbReference type="GeneID" id="5003497"/>
    <dbReference type="Gramene" id="ABO97527">
        <property type="protein sequence ID" value="ABO97527"/>
        <property type="gene ID" value="OSTLU_33271"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33271"/>
    <dbReference type="eggNOG" id="KOG3228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068312_0_1_1"/>
    <dbReference type="OMA" id="KYREHGQ"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="88"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25579" checksum="421CFAE6C6E34980" modified="2007-05-15" version="1">MTTAHRPTWAPAKGKEHQGGARLFGPSAKHSKLDANGFMTLKTRHESQSGADALLARDLRAELEEKERRAKGKGAIAGADVKETIAALGSGASDDGGRFRTRAEDADDDASASGSDDESDSGSDDESDDDDTAALLAELERIKSERAEEARLKAEAEASEAFERQKDELATGNPLLDLATGGAGASAGGDFRTKRRWDDDVVFRNQARDEPKVGKRFINDTIRSDFHKRFLNKYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S245</accession>
    <name>A4S245_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="3 12">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_35087</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="3 12"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419682.1">
        <property type="nucleotide sequence ID" value="XM_001419645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S245"/>
    <dbReference type="STRING" id="436017.A4S245"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="GeneID" id="5003718"/>
    <dbReference type="Gramene" id="ABO97975">
        <property type="protein sequence ID" value="ABO97975"/>
        <property type="gene ID" value="OSTLU_35087"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35087"/>
    <dbReference type="eggNOG" id="KOG1387">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017896_1_1_1"/>
    <dbReference type="OMA" id="ARLYGWV"/>
    <dbReference type="OrthoDB" id="2276068at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009832">
        <property type="term" value="P:plant-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006970">
        <property type="term" value="P:response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="23"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="273"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="471" mass="52326" checksum="79BC75D6D46387CE" modified="2007-05-15" version="1">MFKTSAKQRRRVRGVVRGAGRGRVIGFYHPSGGDGGGGERVLFAAIAAAQRATEGRDVTCCVYAGATSARGDEPVEDGDELIARARERFGIELRAPINVIRLTRERWARAETYKRCTILGQFIGGAWLGLEALWTFAPDVFVDTVGHAATYPIARYLFGCQTVAYVHYPTVSRDMIARVESGRLMYNNSRLFASSKFLSGLKVLYYRAFAVVYGWCGRSCKCVMVNSSWTKSHIDALWRVDSRVVYPPCNVEDLSKLPLTRPRLNARGTPVKKDKSSIRVVSVGQFRPEKAHVVQIAAWKALKKFKTLSSKIENAILVFVGGCRDEADRERLADLQQSVKDLELQDSVQFHVDVSYDEVKRELSRASIGLHSMIDEHFGICVVEYMAAGAVPVAHASGGPFLDIIRDQHDGPTGFTADSVATFAETLEHLLLMRRTEREEISARARARSDIFSETEFNSNFIDSLVNSGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S298</accession>
    <name>A4S298_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419712.1">
        <property type="nucleotide sequence ID" value="XM_001419675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S298"/>
    <dbReference type="GeneID" id="5003584"/>
    <dbReference type="Gramene" id="ABO98005">
        <property type="protein sequence ID" value="ABO98005"/>
        <property type="gene ID" value="OSTLU_33374"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33374"/>
    <dbReference type="HOGENOM" id="CLU_1024478_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="30538" checksum="5C1461C8C0224A9B" modified="2007-05-15" version="1">MPTTEYRAHVTGDPETCACILRESWPDAAAWPRGQTLSFGTGAFCDFTTLLATRRGHIRCLKYAVENGCALHPNLLREATDVPTQMQCFKYALELGLEVDYDAVHTACQNTSVTRITLLIEAYQEQTKRRKRKREDDAKNMIVERGSAFIGAVCANAARGQPGEVIQCIDFLRECGCGWSETATWNVARKGVVRVLKHLVENGCPWDDETLASAEKSGDAETIAFAKRHDKKVKQRKSLETMFNVIESRKEQMTEQEYIDACRAAKDLHDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2B8</accession>
    <name>A4S2B8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="3">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_33394</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ROX family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419502.1">
        <property type="nucleotide sequence ID" value="XM_001419465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2B8"/>
    <dbReference type="GeneID" id="5003726"/>
    <dbReference type="Gramene" id="ABO97795">
        <property type="protein sequence ID" value="ABO97795"/>
        <property type="gene ID" value="OSTLU_33394"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33394"/>
    <dbReference type="eggNOG" id="ENOG502S0FU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039125_1_0_1"/>
    <dbReference type="OMA" id="RWSDPWL"/>
    <dbReference type="OrthoDB" id="425950at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.30">
        <property type="entry name" value="50S ribosomal protein L16 arginine hydroxylase, Chain A, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="4">
        <location>
            <begin position="86"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="392" mass="44049" checksum="47FC68759416A7EE" modified="2007-05-15" version="1">MREYWQKKPLLMRQAIPNFRPPLDGNEIAGLACEEDASARIFVREGDDEQSWRKKIGPFEESDLTSLPEDKPWSLIVNDLDVQAQPFGDMLELFNCFPRWRISDIQASVSPDGGGVGPHSDHFDVFLLQAEGEKVWAVADNEEYWPDNDAAFVPECEIRVLKSFVEDDSFTLVPGDMLYLPPKIAHNGVATNSKPGVSVTLSIGFLAPTTDELVLSYTQRASEKLKGSRWSDPWLKPVEDVGAISAESITYASEIIKRTYPKNDAEVARWFGCHTTARTGEDDDADENEVSIEELLAAWEHQGLVAREDLRFAFVEKVADDSLKNALFFANGECWDVVSPAAVKTATVIANRGELYEEDTQTEECDFDDEALKLALTLFERGYLYFPEDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2K8</accession>
    <name>A4S2K8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DHHA2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_33487</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419770.1">
        <property type="nucleotide sequence ID" value="XM_001419733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2K8"/>
    <dbReference type="STRING" id="436017.A4S2K8"/>
    <dbReference type="GeneID" id="5003667"/>
    <dbReference type="Gramene" id="ABO98063">
        <property type="protein sequence ID" value="ABO98063"/>
        <property type="gene ID" value="OSTLU_33487"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33487"/>
    <dbReference type="eggNOG" id="KOG4129">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019358_1_0_1"/>
    <dbReference type="OMA" id="TMTIFFN"/>
    <dbReference type="OrthoDB" id="374045at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="5">
        <location>
            <begin position="240"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="394" mass="42694" checksum="C1FD0E989A6E14F8" modified="2007-05-15" version="1">MATRANVDDGAREANALRTFLRDAKEAFARDPGACDVSVGNEACDLDSVACAVATARAASAKRGRDDGERETRAVPIVSCAREELKLRPDVVLALANAGVKLGDLTCAEDVAAAATKATPRSVTLVDHNALSARLFPDAWQARVVRVIDHHEDSGMYAERADRVIELIGSCSSLVYRDVVAKAADEGVARDVARLLLGAIVLDTRMLDATTTRAAPVDFAAAESLRDILGWDEDATRAEYESLSRARHDQSSFSCAQLLAKDYKQWTMGSLEVGIASFGVRFQDLLARQDASSVNDEIVAFVDARRIDVLFMMSSFEDADADGAFARQIDVTKSSACSIELEAVMRDLGERTPLAPLRLPENDFGVFKSARAQLDVKASRKKVQPILLEILARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="114" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2L3</accession>
    <name>A4S2L3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="3">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">OSTLU_164</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419550.1">
        <property type="nucleotide sequence ID" value="XM_001419513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2L3"/>
    <dbReference type="STRING" id="436017.A4S2L3"/>
    <dbReference type="GeneID" id="5003606"/>
    <dbReference type="Gramene" id="ABO97843">
        <property type="protein sequence ID" value="ABO97843"/>
        <property type="gene ID" value="OSTLU_164"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_164"/>
    <dbReference type="eggNOG" id="KOG0204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_9_2_1"/>
    <dbReference type="OMA" id="GIMWRNI"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000029">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="699"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="723"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="856"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="894"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="18">
        <location>
            <begin position="123"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="19">
        <location>
            <begin position="720"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ABO97843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="920" mass="99276" checksum="6A1777990D7B7394" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2R2</accession>
    <name>A4S2R2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine-S-conjugate beta-lyase</fullName>
            <ecNumber evidence="3">4.4.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cysteine-S-conjugate beta-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CBL1</name>
        <name evidence="13" type="ORF">OSTLU_88245</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L,L-cystathionine + H2O = L-homocysteine + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13965"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:13966"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms homodimers. May form homotetramers from two homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.13" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419577.1">
        <property type="nucleotide sequence ID" value="XM_001419540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2R2"/>
    <dbReference type="STRING" id="436017.A4S2R2"/>
    <dbReference type="GeneID" id="5003575"/>
    <dbReference type="Gramene" id="ABO97870">
        <property type="protein sequence ID" value="ABO97870"/>
        <property type="gene ID" value="OSTLU_88245"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88245"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_0_1"/>
    <dbReference type="OMA" id="YKQDGVG"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000033">
        <property type="entry name" value="Cystathionine gamma-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000009">
        <property type="entry name" value="Cystathionine gamma-synthase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006238">
        <property type="entry name" value="Cys_b_lyase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01329">
        <property type="entry name" value="cysta_beta_ly_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF50">
        <property type="entry name" value="CYSTATHIONINE BETA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 11 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00064715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="404" mass="43357" checksum="1F2FFFEE55B1C9AB" modified="2007-05-15" version="1">MSAGTSGDEPVARDPKDYKIATKLAHAKTSVTDPYGASAPPLYQTATFAQPSATENGPYDYTRSGNPTRTQLEEQMANLECADRAFAFSSGMSALMCVTRLVNAGERIVTGDDIYGGTSRLLAQVVPKVGIEVVNVDMNDHDAVRAAIQGGNTTMVMMESPTNPRLQVIDIKAICDMAHEKGALVCVDNSIMCPTFQAPLALGADISMTSATKFIAGHSDVTGGLLACNGEELGNRIYFHQNAEGLHLGPFDCWLALRGLKTMQLRMERQQENAMKLTAWLESHPRVNKVNYPGLKANVGHELHSKQASGAGSIFSFTTGDVEFSKIVVEETKLHKITVSFGGTTSLISLPCFMSHASIPAEVRAARGLPDDLVRISCGIEDADDLLADLQYAFAVAEKRVGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Z0</accession>
    <name>A4S2Z0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_2719</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419620.1">
        <property type="nucleotide sequence ID" value="XM_001419583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Z0"/>
    <dbReference type="SMR" id="A4S2Z0"/>
    <dbReference type="STRING" id="436017.A4S2Z0"/>
    <dbReference type="GeneID" id="5003831"/>
    <dbReference type="Gramene" id="ABO97913">
        <property type="protein sequence ID" value="ABO97913"/>
        <property type="gene ID" value="OSTLU_2719"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2719"/>
    <dbReference type="eggNOG" id="KOG1137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008727_4_0_1"/>
    <dbReference type="OMA" id="KNTCVFE"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060918">
        <property type="term" value="P:auxin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009416">
        <property type="term" value="P:response to light stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd07714">
        <property type="entry name" value="RNaseJ_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055132">
        <property type="entry name" value="RNase_J_b_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43694">
        <property type="entry name" value="RIBONUCLEASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43694:SF1">
        <property type="entry name" value="RIBONUCLEASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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            <position position="1"/>
        </location>
    </feature>
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        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
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    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO97913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="413" mass="45990" checksum="6776EB5EA8D4656A" modified="2007-05-15" version="1" fragment="single">IDDPPLKILPLGGLGEIGMNCMLVGSGDRYVLLDAGLMFPDHEELGIQKVLPDVSFLARWKDKIEAVLITHGHEDHIGALPWVVPALDPSTPIYAGLFTMQLIKRRMQEYSLWNDQRFKVFDMNERFQAGPFEMEAVRVTHSIPDCCGLIFRSEHGTIVHTGDWKIDENPVDGRIFDRTSWERVGNEGVTLMMSDSTNVLSPGRTISESAVSEGIMRRVLGHRGRIITTQFASNIHRLYGVRAAAEATGRQIAFLGMSLTTYLEAAKRAGIAPIDPEKLIPADEIDNCDPSKLLIVTTGSQGEERAQLALAAHGSSRLLTLQPEDLLLYSAKMIPGNEKRVMRMMNEIAKRGPEIAMGREDCLHSSGHGYKDELDEVIKLLKPEHFLPVHGEYAFLRAHEQLARQSGVRHTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S320</accession>
    <name>A4S320_OSTLU</name>
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        <recommendedName>
            <fullName evidence="2">GYF domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">OSTLU_93284</name>
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    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_93284"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93284"/>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
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        <property type="entry name" value="GRB10 INTERACTING GYF PROTEIN"/>
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        </location>
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        <location>
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    </feature>
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        <location>
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        </location>
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        <location>
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        <location>
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        </location>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
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        <location>
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        </location>
    </feature>
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            <end position="643"/>
        </location>
    </feature>
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        <location>
            <begin position="644"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
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            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="919" mass="96911" checksum="37BE50FCB01E2FDA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S362</accession>
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        <recommendedName>
            <fullName evidence="3">Protein MCM10 homolog</fullName>
        </recommendedName>
    </protein>
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        <name evidence="11" type="ORF">OSTLU_16917</name>
    </gene>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM10 family.</text>
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    <dbReference type="eggNOG" id="KOG3056">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_451593_0_0_1"/>
    <dbReference type="OMA" id="FRLDTIH"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22379">
        <property type="entry name" value="OB_MCM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01280">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="192"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="395"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="340"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="403"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="421"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="605" mass="66154" checksum="C05C6F118A8F831E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3C6</accession>
    <name>A4S3C6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine(9)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_26008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420071.1">
        <property type="nucleotide sequence ID" value="XM_001420034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3C6"/>
    <dbReference type="STRING" id="436017.A4S3C6"/>
    <dbReference type="GeneID" id="5004131"/>
    <dbReference type="Gramene" id="ABO98364">
        <property type="protein sequence ID" value="ABO98364"/>
        <property type="gene ID" value="OSTLU_26008"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26008"/>
    <dbReference type="eggNOG" id="KOG2967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_883937_0_0_1"/>
    <dbReference type="OMA" id="ALQAWFP"/>
    <dbReference type="OrthoDB" id="278300at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052905">
        <property type="term" value="F:tRNA (guanosine(9)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="7">
        <location>
            <begin position="69"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="269"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="315" mass="35659" checksum="C1FAE5AA5CFE29CC" modified="2007-05-15" version="1">MKKRLKRQRRCDAKLAKRAEAKRRKADVAASTKAAFHSKVNAMSSEARDAFFVERGARIEARRRETAERKERRRAQLSSAYGLTIDCDEDLTTTMERERWGSLMKQLRAAYERNCKTTAPFKMSFTRMSEAFEEQMGRMNAGWENWHVVRLGKTLRETAAESETTAKSLVYLTADSERELREIEAGKTYVIGGFIDRNRHKGLTLRKARELGVEHARLPIGEFLETRGAPVLTVNQTADVLTSFLERGDWGEAIEAVVPARKVVKIANRSNEADAKIKDAERARDEDEDEDEDEDASPTADDDDDAPTSTDGAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3V9</accession>
    <name>A4S3V9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_26189</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mis12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420162.1">
        <property type="nucleotide sequence ID" value="XM_001420125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3V9"/>
    <dbReference type="GeneID" id="5004027"/>
    <dbReference type="Gramene" id="ABO98455">
        <property type="protein sequence ID" value="ABO98455"/>
        <property type="gene ID" value="OSTLU_26189"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26189"/>
    <dbReference type="HOGENOM" id="CLU_1108581_0_0_1"/>
    <dbReference type="OMA" id="RSRDIMD"/>
    <dbReference type="OrthoDB" id="496023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008685">
        <property type="entry name" value="Centromere_Mis12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527:SF2">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05859">
        <property type="entry name" value="Mis12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="251" mass="27435" checksum="214A7630F6FD6173" modified="2007-05-15" version="1">MPDPIPCARAREQRERSKDVCDDITNAVEHYAAEGFDALESCLNEETDPDERTKAAFKHGLDALYAKLQLKIGDNFNRFCSHAKAACFAIPSEVIEYESRVEEIDALPSVSEEEESALDGELRSLRARISRARALKTTSEKECKALDKELESHVEVVGRIQAITAAVGKENARVKEGLNAAGAIVHTAKQLQPLLAQAEAMQRTGGFMPERSTSIDPVVMANNAVKQHFIQGSSLSVLRSLNAKLSSQVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Y9</accession>
    <name>A4S3Y9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Uncharacterized protein ycf33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26220</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ycf33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420003.1">
        <property type="nucleotide sequence ID" value="XM_001419966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Y9"/>
    <dbReference type="GeneID" id="5003962"/>
    <dbReference type="Gramene" id="ABO98296">
        <property type="protein sequence ID" value="ABO98296"/>
        <property type="gene ID" value="OSTLU_26220"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26220"/>
    <dbReference type="eggNOG" id="ENOG502SF85">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166368_0_0_1"/>
    <dbReference type="OrthoDB" id="1900844at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008470">
        <property type="entry name" value="Uncharacterised_Ycf33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36049:SF3">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36049">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05421">
        <property type="entry name" value="DUF751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="9951" checksum="7A9CD0F6DEA4A1BD" modified="2007-05-15" version="1">MADGADNSAAATTTPNELFALAGGEVPFWANMVKYARFSISIMVGFAYMFGRPVAALLKKPQTAAAVVAVGAGGYVFFKFTIETMLGMNDPSTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="124" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4I0</accession>
    <name>A4S4I0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication licensing factor MCM2</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_44312</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420441.1">
        <property type="nucleotide sequence ID" value="XM_001420404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4I0"/>
    <dbReference type="STRING" id="436017.A4S4I0"/>
    <dbReference type="GeneID" id="5004337"/>
    <dbReference type="Gramene" id="ABO98734">
        <property type="protein sequence ID" value="ABO98734"/>
        <property type="gene ID" value="OSTLU_44312"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44312"/>
    <dbReference type="eggNOG" id="KOG0477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_0_1_1"/>
    <dbReference type="OMA" id="KFARYTH"/>
    <dbReference type="OrthoDB" id="844at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000347">
        <property type="term" value="C:THO complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042127">
        <property type="term" value="P:regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010082">
        <property type="term" value="P:regulation of root meristem growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000138">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008045">
        <property type="entry name" value="MCM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059098">
        <property type="entry name" value="WHD_MCM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF44">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23669">
        <property type="entry name" value="WHD_MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01658">
        <property type="entry name" value="MCMPROTEIN2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="18">
        <location>
            <begin position="360"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO98734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="796" mass="90236" checksum="A3050AA503AA1BAB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S503</accession>
    <name>A4S503_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420357.1">
        <property type="nucleotide sequence ID" value="XM_001420320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S503"/>
    <dbReference type="GeneID" id="5004413"/>
    <dbReference type="Gramene" id="ABO98650">
        <property type="protein sequence ID" value="ABO98650"/>
        <property type="gene ID" value="OSTLU_26591"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26591"/>
    <dbReference type="eggNOG" id="ENOG502T2JY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142482_0_0_1"/>
    <dbReference type="OMA" id="DEGWAPR"/>
    <dbReference type="OrthoDB" id="513668at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="13709" checksum="D6B26D23F6EBDFA9" modified="2007-05-15" version="1">MPMRAIADAIGDAFGPALDAIAEERRRRGEARRDGGETEDETEAGLYVPDIPAFLCATRLARDSPMVRSVLVVDERAPRTKPRLSWYDVDDEGWAPRGWWEDGVKADFAYYFGERRESSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S526</accession>
    <name>A4S526_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_88673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420536.1">
        <property type="nucleotide sequence ID" value="XM_001420499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S526"/>
    <dbReference type="STRING" id="436017.A4S526"/>
    <dbReference type="GeneID" id="5004431"/>
    <dbReference type="KEGG" id="olu:OSTLU_88673"/>
    <dbReference type="eggNOG" id="KOG1716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023312_1_0_1"/>
    <dbReference type="OMA" id="SFTWING"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016278">
        <property type="entry name" value="DUSP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000941">
        <property type="entry name" value="DUSP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="33"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="5">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000941-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="29532" checksum="1D4DC11A3764E579" modified="2007-05-15" version="1" fragment="single">LRRQGRIDASRTLVVPLPDDDLADLLGVVPEATTFIETALASASSSVVAVHCHAGESRSAAVVAAYLMRFEQLEIEQAMASVEARGGAPNEGFQAQLSLWAQMGCRVSTANEAYKLWSVAKVARERDERGYLESTSVMRDPGAADAVDDPEGGGWLACRKCRRRLARSTHVLCHEHGEGIDAFSWKARRKEGSKGINRDCAGARQCSSMFLTPLSWMKGIEDGDGGETRGKLCCPQCETKIGAFDWAGIQCSCGAWVSPAFQIQRAKTDAFGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S550</accession>
    <name>A4S550_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TPR3a</name>
        <name evidence="6" type="ORF">OSTLU_26637</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420547.1">
        <property type="nucleotide sequence ID" value="XM_001420510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S550"/>
    <dbReference type="STRING" id="436017.A4S550"/>
    <dbReference type="GeneID" id="5004444"/>
    <dbReference type="Gramene" id="ABO98840">
        <property type="protein sequence ID" value="ABO98840"/>
        <property type="gene ID" value="OSTLU_26637"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26637"/>
    <dbReference type="eggNOG" id="KOG0543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1043492_0_0_1"/>
    <dbReference type="OMA" id="RRYDECA"/>
    <dbReference type="OrthoDB" id="1872379at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF9">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="267" mass="29526" checksum="4D15D5E96CC2607D" modified="2007-05-15" version="1">MRVGERVGIVVPSGGAPFASEPFSPAPRNVYVEWEVELLSVTREEKPSVDASVEEVLRYCERKKEEANALFARGEEENGYARALRRYEDAATALRRTIMSTARAGAKDALALAVKCHVNSATCLSKLQRHSEAILHAEAALDLDATAVKAMYRKAMALEQQGRDEEALTSLRDALELSKDRAIREAFVRVRRRMNAVHEGEREVCARMVQTDPTTEPTTRGFGERAAQLYRKRPALAGAITVAAFAAMVMYFRRSEKSASTTTATSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S570</accession>
    <name>A4S570_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_9473</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BBP/SF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420720.1">
        <property type="nucleotide sequence ID" value="XM_001420683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S570"/>
    <dbReference type="STRING" id="436017.A4S570"/>
    <dbReference type="GeneID" id="5004738"/>
    <dbReference type="Gramene" id="ABO99013">
        <property type="protein sequence ID" value="ABO99013"/>
        <property type="gene ID" value="OSTLU_9473"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9473"/>
    <dbReference type="eggNOG" id="KOG0119">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2177483_0_0_1"/>
    <dbReference type="OMA" id="EGRTHQK"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045131">
        <property type="term" value="F:pre-mRNA branch point binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="36"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="115" mass="13297" checksum="C45CC57B018BED19" modified="2007-05-15" version="1" fragment="single">REVVEREKFQRRRMELLEDICRKCPMFRPPPDYRPNKRTAKLLIPVDEYPGYNFFGLIIGPRGSTQKQMQRETNTKIVIRGRGSAKGGTGAAERNNEFDHEPLHVLIEGDVQSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S657</accession>
    <name>A4S657_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_5006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421033.1">
        <property type="nucleotide sequence ID" value="XM_001420996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S657"/>
    <dbReference type="STRING" id="436017.A4S657"/>
    <dbReference type="GeneID" id="5005094"/>
    <dbReference type="Gramene" id="ABO99326">
        <property type="protein sequence ID" value="ABO99326"/>
        <property type="gene ID" value="OSTLU_5006"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5006"/>
    <dbReference type="eggNOG" id="KOG1499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017375_1_2_1"/>
    <dbReference type="OMA" id="HENMVRD"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF89">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="27"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="6">
        <location>
            <begin position="133"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="29511" checksum="4D9FFE8B66061F30" modified="2007-05-15" version="1" fragment="single">MIGDTARTDAYRDALEKNPTLIQGKRVLDIGCGTGILSMFAARGGASAVVGVDGAKHIAEVAKANVKHNGFSDRIQIVYGKLEDIEGDIPGAPFDVLVSEWMGYGLLFESMLDTVLVARNRFLKPGGAVLPDIATIHIAGFDRKATDFPFWEDVYGFEMPEIKKQLFQGAMKTAVVTHVDGARLTTSGSQVCELDLATCSIADTEFTTEFSLSAKDGRIGEETHGIVLWFDTEFSKRFCADLAVMLSTSPEAKKTHWVQTMLHFREPITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S676</accession>
    <name>A4S676_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421042.1">
        <property type="nucleotide sequence ID" value="XM_001421005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S676"/>
    <dbReference type="STRING" id="436017.A4S676"/>
    <dbReference type="GeneID" id="5005104"/>
    <dbReference type="Gramene" id="ABO99335">
        <property type="protein sequence ID" value="ABO99335"/>
        <property type="gene ID" value="OSTLU_25378"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25378"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_615881_0_0_1"/>
    <dbReference type="OMA" id="WSEDAMD"/>
    <dbReference type="OrthoDB" id="494131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="518" mass="58196" checksum="95F0A0BC3D2902AF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S694</accession>
    <name>A4S694_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420905.1">
        <property type="nucleotide sequence ID" value="XM_001420868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S694"/>
    <dbReference type="GeneID" id="5005083"/>
    <dbReference type="Gramene" id="ABO99198">
        <property type="protein sequence ID" value="ABO99198"/>
        <property type="gene ID" value="OSTLU_27037"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27037"/>
    <dbReference type="HOGENOM" id="CLU_1505429_0_0_1"/>
    <dbReference type="OMA" id="WRCFEDY"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18143">
        <property type="entry name" value="HAD_SAK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="18350" checksum="3AA98438A0197A54" modified="2007-05-15" version="1">MAAPRRPVLLLDVDGVLNRTATAKQIALDEDLIALLRDVAERSACEVVLTTYWRYFEEYLAYAFERHGLPKGAVAGRTAGEPHRSDSVAHDSKVPELRVLEIERYMRETHGEDETAWPPFAVVDDKEVVSAEHRWRGRFVRTKHDVGLTKAQADALIDILSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="115" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6N8</accession>
    <name>A4S6N8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">[histone H3]-trimethyl-L-lysine(4) demethylase</fullName>
            <ecNumber evidence="4">1.14.11.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_17878</name>
        <name evidence="20" type="ORF">OSTLU_19230</name>
    </gene>
    <organism evidence="19 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 2-oxoglutarate + 3 O2 = L-lysyl(4)-[histone H3] + 3 formaldehyde + 3 succinate + 3 CO2</text>
            <dbReference type="Rhea" id="RHEA:60208"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.67" evidence="4"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421122.1">
        <property type="nucleotide sequence ID" value="XM_001421085.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422832.1">
        <property type="nucleotide sequence ID" value="XM_001422795.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S6N8"/>
    <dbReference type="GeneID" id="5004978"/>
    <dbReference type="GeneID" id="5006973"/>
    <dbReference type="Gramene" id="ABO99415">
        <property type="protein sequence ID" value="ABO99415"/>
        <property type="gene ID" value="OSTLU_17878"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01191">
        <property type="protein sequence ID" value="ABP01191"/>
        <property type="gene ID" value="OSTLU_19230"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17878"/>
    <dbReference type="KEGG" id="olu:OSTLU_19230"/>
    <dbReference type="eggNOG" id="KOG1246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_246699_0_0_1"/>
    <dbReference type="OrthoDB" id="19286at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034647">
        <property type="term" value="F:histone H3K4me/H3K4me2/H3K4me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15545">
        <property type="entry name" value="PHD_BAZ2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048615">
        <property type="entry name" value="KDM5_C-hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013637">
        <property type="entry name" value="Lys_sp_deMease-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004198">
        <property type="entry name" value="Znf_C5HC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF33">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21323">
        <property type="entry name" value="KDM5_C-hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08429">
        <property type="entry name" value="PLU-1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02928">
        <property type="entry name" value="zf-C5HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ARID" evidence="17">
        <location>
            <begin position="88"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="16">
        <location>
            <begin position="299"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="18">
        <location>
            <begin position="451"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="676"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1255"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="690"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO99415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABP01191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1544" mass="170910" checksum="C90C0ADCC4BDFA5F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7F6</accession>
    <name>A4S7F6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_43365</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterotrimer of RPA1, RPA2 and RPA3 (canonical replication protein A complex).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421265.1">
        <property type="nucleotide sequence ID" value="XM_001421228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7F6"/>
    <dbReference type="STRING" id="436017.A4S7F6"/>
    <dbReference type="GeneID" id="5005310"/>
    <dbReference type="Gramene" id="ABO99558">
        <property type="protein sequence ID" value="ABO99558"/>
        <property type="gene ID" value="OSTLU_43365"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43365"/>
    <dbReference type="eggNOG" id="KOG0851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012393_3_1_1"/>
    <dbReference type="OMA" id="CATISFM"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000064">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000090">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="14">
        <location>
            <begin position="5"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="16">
        <location>
            <begin position="325"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="15">
        <location>
            <begin position="490"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="159"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO99558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="649" mass="70898" checksum="E15EC303E0F02986" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7G3</accession>
    <name>A4S7G3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein bL9c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">CL9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRPL9A</name>
        <name evidence="8" type="ORF">OSTLU_18094</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421450.1">
        <property type="nucleotide sequence ID" value="XM_001421413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7G3"/>
    <dbReference type="STRING" id="436017.A4S7G3"/>
    <dbReference type="GeneID" id="5005315"/>
    <dbReference type="Gramene" id="ABO99743">
        <property type="protein sequence ID" value="ABO99743"/>
        <property type="gene ID" value="OSTLU_18094"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18094"/>
    <dbReference type="eggNOG" id="KOG4607">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1436630_0_0_1"/>
    <dbReference type="OMA" id="MRVERRW"/>
    <dbReference type="OrthoDB" id="5555409at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="entry name" value="Ribosomal protein L9, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_bL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_bL9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_bL9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein L9" evidence="7">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="189" mass="21370" checksum="0C7B862995E6AB1E" modified="2007-05-15" version="1">MPASMRVERRWWKKANRRVEVILRAPVSGLGDVDEVAHVRPGRARNHLVPGKLATYVNAEKLAAARERLAARERARIEAGGEDGDEAAATAQEEEHKRKERATVMKMLTAEPAIAFRRIKDKKTGKPRIAVTRENIVEEIRRQKSLNLTPGALMLERPIVDFGEYDIPLFIRGEPVGERTVPVVVRERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7K0</accession>
    <name>A4S7K0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421288.1">
        <property type="nucleotide sequence ID" value="XM_001421251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7K0"/>
    <dbReference type="GeneID" id="5005335"/>
    <dbReference type="Gramene" id="ABO99581">
        <property type="protein sequence ID" value="ABO99581"/>
        <property type="gene ID" value="OSTLU_18124"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18124"/>
    <dbReference type="eggNOG" id="ENOG502QVZR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1231647_0_0_1"/>
    <dbReference type="OMA" id="VLPCNVF"/>
    <dbReference type="OrthoDB" id="508259at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33344">
        <property type="entry name" value="OS02G0761600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="24355" checksum="E14B18DE5F28D5B3" modified="2007-05-15" version="1">MPRADALAPEVEETRAETAAATALAPEVEETTTPANVRRRERECGSPAVDGYAHVNLTCLAMSATAREFAHASASGREKLRAHIEEHASYDGVAVRWGIHHTTETAEECGERCKEHVVKPDGIGAEVLPCNVFVWCPKDVGEGGCFEPDAHQHFAGDCWLKFSETPENVEVNQRGANDAPGFVNKDGKTFAERHANAPKLVHWSSGVLLPESMTASSTLGPRATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Z6</accession>
    <name>A4S7Z6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_9952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421539.1">
        <property type="nucleotide sequence ID" value="XM_001421502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Z6"/>
    <dbReference type="STRING" id="436017.A4S7Z6"/>
    <dbReference type="GeneID" id="5005445"/>
    <dbReference type="Gramene" id="ABO99832">
        <property type="protein sequence ID" value="ABO99832"/>
        <property type="gene ID" value="OSTLU_9952"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9952"/>
    <dbReference type="eggNOG" id="ENOG502S3ZV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_175131_1_0_1"/>
    <dbReference type="OrthoDB" id="5516192at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36706">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="53" mass="6219" checksum="8C6325B2F958B04C" modified="2007-05-15" version="1" fragment="single">KRARQHRCNDRLEDVVQSLFEGNPLLTTPPAWSLFVKCMRSEVGDEPRDPFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S867</accession>
    <name>A4S867_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421710.1">
        <property type="nucleotide sequence ID" value="XM_001421673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S867"/>
    <dbReference type="GeneID" id="5005611"/>
    <dbReference type="Gramene" id="ABP00004">
        <property type="protein sequence ID" value="ABP00004"/>
        <property type="gene ID" value="OSTLU_93774"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93774"/>
    <dbReference type="HOGENOM" id="CLU_535755_0_0_1"/>
    <dbReference type="OrthoDB" id="10588274at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="509" mass="53806" checksum="0C221D469E9D2BFD" modified="2007-05-15" version="1">MRPRGARSRSAVVLERAADDYVDRPARRVSIGVSNADGDASSDDEGATRFECHALATSRGVVACAGCAPSAPGDGVVYFAPRGRGRGVWRRARGARGCASAAATRDDADEFAVGMTDGSVWVYRCARERGMEASKVATLTPPGWDAGWGRARDASATRCARLVVVGRARRAGTLVARHGSGGASLAVWDVETLSPSTASGEAKGFASMAKSTWLGTTSAYAALGGDGFVATSMDQKSVAAVEVNDLGRARLIWRSRREPGRGVFLAGAAVIDRGGTLSSRAATCSCEEMVHGTTYAAPDSSVKLVILDAEDGAEVNRFSIEGLGASNVFIDCGSLCSVGGSLFLAHRDGAIWVINPGNGALITSLHPAQHFHDTSGHRRTLPSLLAITPARDEMYGATCDGGVAHCWRVGNPTRWSRASHKNFPAAFRESVRTLLLCVHAHVNPTRAMMRVKLAPRNVADDDDVDVDGHERLRHVEGFIDAAAREPALLEMIVGRMARALFGCEVDDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8L7</accession>
    <name>A4S8L7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27893</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421645.1">
        <property type="nucleotide sequence ID" value="XM_001421608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8L7"/>
    <dbReference type="STRING" id="436017.A4S8L7"/>
    <dbReference type="GeneID" id="5005754"/>
    <dbReference type="Gramene" id="ABO99938">
        <property type="protein sequence ID" value="ABO99938"/>
        <property type="gene ID" value="OSTLU_27893"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27893"/>
    <dbReference type="eggNOG" id="KOG4373">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_710570_0_0_1"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="4">
        <location>
            <begin position="298"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="389" mass="42120" checksum="02C035FC5370E054" modified="2007-05-15" version="1">MRVPSAAKNIRNAAARLLSAEPPPSVASSVVDPFALPPVDVAYDVESAERALALRGFAPSAAPGAPRFIGFDVETKPNFTKNVANVNAPALVQLANERGCVLVHLASMRGETPPTLRALCEDAGSIFVGNGVWSDMRDVDWAFGTKSRGYVDVGVIAQTFGHSRHGLKAMSARYGYDAEKPKSVQTSNWEKSPLEAKQIDYGAKDAALGLWVLKQLYAEYAGGEVSLEDWAMAFGNASQPKEAFRSARANAKTTPECVMKAFERFDQKNRELVKEAWLVRQMKKAQRVVKQMAEGALHPVSATHALMDILHAPKSKRKVVEWVGSGSKGGGLFEIELKLGSSVRARGEGRTVKAAKFEAARGAFAALKDGDAADATIWIKRELEHAWSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8P7</accession>
    <name>A4S8P7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:ubiquinone oxidoreductase intermediate-associated protein 30 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_1559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421664.1">
        <property type="nucleotide sequence ID" value="XM_001421627.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8P7"/>
    <dbReference type="STRING" id="436017.A4S8P7"/>
    <dbReference type="GeneID" id="5005774"/>
    <dbReference type="Gramene" id="ABO99957">
        <property type="protein sequence ID" value="ABO99957"/>
        <property type="gene ID" value="OSTLU_1559"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1559"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029746_0_0_1"/>
    <dbReference type="OMA" id="HTMTIRF"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.430">
        <property type="entry name" value="Galactose-binding lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF47">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="70"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="1">
        <location>
            <begin position="211"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="347"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="54046" checksum="4D8CB418C3B284AC" modified="2007-05-15" version="1" fragment="single">VNPVNLGRKSRAAFENVFKQLTSLTSFQKSTAPTNAREFDQVYDADLLSGSSVGEFETPNAKFTTVLVTGATGRIGRVLIRKLLLRGYTVKALVRRQEDVEKLPGLVQVIVGDVGEKEVIKNAMIGVNKVIYCASAKTSVTSDLYNVADQGVKNVVSCMQDYYHMLASRRAGRSAKSKVMLTNFKHPTAYEAWDRVNFDPLYPEDEDKPFEFATFNGFITSRTGKAEVSSNVEGLQADVDFSAKEGLLFRLKGDGKRYSVMLTQDDGSKFRFSFNTTGGWQVIRMPFHKFVSEGKTSWGDDGDAILDLTRIEKIGVRFDARKNQRETTMSDVMSGNNNMFNLTLEYVKAIPKGEEPDVILVSCFGAGLEEGEEKERILKIKRDGERVLRNSGVGYTIVRPGELVEEAGGGKALVFDQTERINTPISCADVSDVCVKAMHDEEARNKSFDVGYEYESEQAEYELITQVKGKSDNYLTPALKVLEKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8R1</accession>
    <name>A4S8R1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421805.1">
        <property type="nucleotide sequence ID" value="XM_001421768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8R1"/>
    <dbReference type="GeneID" id="5005807"/>
    <dbReference type="Gramene" id="ABP00099">
        <property type="protein sequence ID" value="ABP00099"/>
        <property type="gene ID" value="OSTLU_27938"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27938"/>
    <dbReference type="eggNOG" id="ENOG502QVAR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109114_0_0_1"/>
    <dbReference type="OMA" id="GWFESLY"/>
    <dbReference type="OrthoDB" id="423069at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="3">
        <location>
            <begin position="16"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="20644" checksum="E568A366288915BF" modified="2007-05-15" version="1">MRRASSSRASSSSSSSSLFELVDASRRGVGVAPNDDARRDIERAIDALASTTRAKGDDARSNNAKSYARWELAYTTEKETLWLLGLKTRSKTRAFQTLREDAKTLSNEVVFNDGEVVFKVDAVVEESSRATMKFRFTAASLTFRDKFSIPIPPVGSGWFENVYVDDERRVSRDSRGDTLICVKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Y9</accession>
    <name>A4S8Y9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PGE3501</name>
        <name evidence="7" type="ORF">OSTLU_37673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421975.1">
        <property type="nucleotide sequence ID" value="XM_001421938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Y9"/>
    <dbReference type="STRING" id="436017.A4S8Y9"/>
    <dbReference type="GeneID" id="5006015"/>
    <dbReference type="Gramene" id="ABP00269">
        <property type="protein sequence ID" value="ABP00269"/>
        <property type="gene ID" value="OSTLU_37673"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37673"/>
    <dbReference type="eggNOG" id="KOG1034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032683_4_0_1"/>
    <dbReference type="OMA" id="VWEMDPS"/>
    <dbReference type="OrthoDB" id="7318948at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="120"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="166"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="391" mass="42009" checksum="E2A8A3D064989C21" modified="2007-05-15" version="1" fragment="single">MARAREAKRASYAPTCAIRDGQERAHVYCARFCAIEGVDGKFQRTFATCAGTRADVWECEKSGNVVLVASFETRDANEAFYACEWCAIDSGKLRPCLALAGEGAVVRVVDCVTGRLHVNLVGHGGTVNSVVSHPSRPSVVATASKDLSVRLWHVNTGVTMAILAGARGHRNELLSVDFHPAIDAKGQMKLVTGAMDNCVKVWATPPLADSMAKAATWTKPLANFKTIVIDTPMFSSSSVHDDYVDCVGWLGDAVLSKSVDGIVKLWVPDEPVGVVHARGNQFRSVSAFEQKDANLWWIRFAVSGSRNAFALGNIKGLVLVWRLDARGGLTRAPARLAAFPVRRSASNNVAPEIALDGFAVVRQCAINRDGDVVVAACDSGLICRWDLATPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S967</accession>
    <name>A4S967_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphorylated adapter RNA export protein RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422010.1">
        <property type="nucleotide sequence ID" value="XM_001421973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S967"/>
    <dbReference type="STRING" id="436017.A4S967"/>
    <dbReference type="GeneID" id="5006050"/>
    <dbReference type="Gramene" id="ABP00304">
        <property type="protein sequence ID" value="ABP00304"/>
        <property type="gene ID" value="OSTLU_28094"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28094"/>
    <dbReference type="HOGENOM" id="CLU_1910171_0_0_1"/>
    <dbReference type="OrthoDB" id="20573at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1440">
        <property type="entry name" value="PHAX RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019385">
        <property type="entry name" value="PHAX_RNA-binding_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038092">
        <property type="entry name" value="PHAX_RNA-binding_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10258">
        <property type="entry name" value="PHAX_RNA-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphorylated adapter RNA export protein RNA-binding" evidence="1">
        <location>
            <begin position="20"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="14901" checksum="363232CBC77B4B71" modified="2007-05-15" version="1">MLDVDDPTRVEMREEDFKCAERVAATIEEPKRHLMRRLARAFGGDAMDAALRETLRIEREGGSKYEAGATGSGIWRRRTKAGCFLWVFKRAHGGAKLEAALRESKAVDKALRARRRGEFGRRGGARGRGRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Q6</accession>
    <name>A4S9Q6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Pseudouridine synthase I TruA alpha/beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_2261</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a uridine in tRNA = a pseudouridine in tRNA</text>
            <dbReference type="Rhea" id="RHEA:54572"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13934"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422107.1">
        <property type="nucleotide sequence ID" value="XM_001422070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9Q6"/>
    <dbReference type="STRING" id="436017.A4S9Q6"/>
    <dbReference type="GeneID" id="5006271"/>
    <dbReference type="Gramene" id="ABP00424">
        <property type="protein sequence ID" value="ABP00424"/>
        <property type="gene ID" value="OSTLU_2261"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2261"/>
    <dbReference type="eggNOG" id="KOG2553">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021971_3_0_1"/>
    <dbReference type="OMA" id="FLCECIY"/>
    <dbReference type="OrthoDB" id="10256309at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02568">
        <property type="entry name" value="PseudoU_synth_PUS1_PUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.580:FF:000002">
        <property type="entry name" value="tRNA pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.660:FF:000002">
        <property type="entry name" value="tRNA pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041708">
        <property type="entry name" value="PUS1/PUS2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF4">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="11">
        <location>
            <begin position="155"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00036943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR641708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR641708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="34437" checksum="2507E2672713F482" modified="2007-05-15" version="1" fragment="single">KKRKCAVTFAYVGAGYAGMQRNPGVRTIEGELEGAIARAGGISDANAGDFAKVQWTRAARTDKGVSAVGQVVALKMVLEPSGMVERINAALPERFEVFGIDRVTGGFNAKTMCDRRRYEYVIPTRAFDPNLGAEGAAEAFAFTEETRSRVDGVLKNYCGTHNFHNYTVKVKPTDAQAKRYIISFECSAPFEVEGEQFVRCQVVGQSFMLHQIRKLIGTMLAVVRGELTEDDQKFALLTHEFVPTPMAPELGLFLCECIYKAYNDKFGGVHENFELAKYSERSESFKQTHVYPHIAKQEREESTMQNWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9R0</accession>
    <name>A4S9R0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6737 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422215.1">
        <property type="nucleotide sequence ID" value="XM_001422178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9R0"/>
    <dbReference type="GeneID" id="5006168"/>
    <dbReference type="Gramene" id="ABP00532">
        <property type="protein sequence ID" value="ABP00532"/>
        <property type="gene ID" value="OSTLU_28285"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28285"/>
    <dbReference type="eggNOG" id="ENOG502RZ63">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_185096_1_0_1"/>
    <dbReference type="OrthoDB" id="1747990at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046625">
        <property type="entry name" value="DUF6737"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36046:SF1">
        <property type="entry name" value="DUF6737 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36046">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20522">
        <property type="entry name" value="DUF6737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6737" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="86" mass="9712" checksum="A3A4A0F5A5937455" modified="2007-05-15" version="1">MWKTKPAWCQPYSIVATGVLATATPVNVLHLDERVAGWFGTLSTTIVGAAVLAWWFLFLYVVPREYERSVEAFREDRRRRGGGDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9X6</accession>
    <name>A4S9X6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="7">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_42027</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HDDC2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="7"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422143.1">
        <property type="nucleotide sequence ID" value="XM_001422106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9X6"/>
    <dbReference type="STRING" id="436017.A4S9X6"/>
    <dbReference type="GeneID" id="5006305"/>
    <dbReference type="Gramene" id="ABP00460">
        <property type="protein sequence ID" value="ABP00460"/>
        <property type="gene ID" value="OSTLU_42027"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42027"/>
    <dbReference type="eggNOG" id="KOG3197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039453_2_1_1"/>
    <dbReference type="OMA" id="MCLFHDL"/>
    <dbReference type="OrthoDB" id="10254258at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000035">
        <property type="entry name" value="HD family hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="11">
        <location>
            <begin position="39"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="153"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="195" mass="21284" checksum="B50A893B43F6774C" modified="2007-05-15" version="1">MPSPSSAAPSARACVDLIARAGKLKALRRAGWVQRGVRDAESVAEHSWRVALMTMLAADRDDACDSGRAVAMALVHDLAEAVVGDITPNDGVSDEEKAAMEREAMGTMTAALGARGEALMALWEEYEAGESAEARLVKDMDKLEMIAQAMEYETEENTGRGEDLEEFFESTRGRYRTATGEAWSEEIERRRPRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Z1</accession>
    <name>A4S9Z1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_28367</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422151.1">
        <property type="nucleotide sequence ID" value="XM_001422114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9Z1"/>
    <dbReference type="STRING" id="436017.A4S9Z1"/>
    <dbReference type="GeneID" id="5006312"/>
    <dbReference type="Gramene" id="ABP00468">
        <property type="protein sequence ID" value="ABP00468"/>
        <property type="gene ID" value="OSTLU_28367"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28367"/>
    <dbReference type="eggNOG" id="KOG0654">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_732254_0_0_1"/>
    <dbReference type="OMA" id="WILDVCA"/>
    <dbReference type="OrthoDB" id="2013528at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20529">
        <property type="entry name" value="CYCLIN_CCNJ-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000010">
        <property type="entry name" value="G1/S-specific cyclin Cln1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="56"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="6">
        <location>
            <begin position="151"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="155"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="35454" checksum="572055ACDF5737B9" modified="2007-05-15" version="1">MVALARARADAIGPDGADLCADVARELLRRERADHGAFVLDGATAHHAAYRAQLVEWILDVCAGERYGPTTADVAIGYMDRVLSKTVVPKTSLHLVALCCLQIAVKYEEIEERVPTMAKLRAWTSNMYSPDIIQKMELAVLIELKWELGILTPAHFLESFLTMMNGGTTSEDEVDVGVWTPQYQEELRHLVCQMYSLCVQDVSLANELPSRVAAAVIAASRLNLGIKPLCPPTLRVAANVTPQQIYPLVTHMHRMWEEAYEDDETTMMEADVKAHADFNSLAIAIPQQEGVVYADKPGFEQRITENASPTCPLDMQWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA08</accession>
    <name>A4SA08_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_42173</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422264.1">
        <property type="nucleotide sequence ID" value="XM_001422227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA08"/>
    <dbReference type="STRING" id="436017.A4SA08"/>
    <dbReference type="GeneID" id="5006321"/>
    <dbReference type="Gramene" id="ABP00581">
        <property type="protein sequence ID" value="ABP00581"/>
        <property type="gene ID" value="OSTLU_42173"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42173"/>
    <dbReference type="eggNOG" id="KOG0667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1708881_0_0_1"/>
    <dbReference type="OMA" id="GKDERDQ"/>
    <dbReference type="OrthoDB" id="25592at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF28">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MINIBRAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="154" mass="17475" checksum="A8B1970303DD6957" modified="2007-05-15" version="1" fragment="single">MHQTEKLGGGYQCLVFEIMSHSLYDLLRVTNLSGVSIKLVRKFAIQIMRALEYTKSLGIIHCDIKPENVLLCHPERSAVKLIDFGSACKCGKQQFSYVQSRFYRAPEVMLGMQYGPAIDMWSAGCMMYELRTGKPLFTGWSEHDQLCRIEATLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA50</accession>
    <name>A4SA50_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_18789</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422317.1">
        <property type="nucleotide sequence ID" value="XM_001422280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA50"/>
    <dbReference type="GeneID" id="5006362"/>
    <dbReference type="Gramene" id="ABP00634">
        <property type="protein sequence ID" value="ABP00634"/>
        <property type="gene ID" value="OSTLU_18789"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18789"/>
    <dbReference type="HOGENOM" id="CLU_697166_0_0_1"/>
    <dbReference type="OMA" id="HSINANC"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="152"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="394" mass="45210" checksum="207C01F42D91AF85" modified="2007-05-15" version="1">MAKTRARRVGLLLLLCFCFSSSYMIVTRTIADLLGSFSALWIREDAWTHCRNCCGDVRERMLKSSLRGLGKDVACFTFHPEASSPSSYTFVARRRQPLNRSYFKSALRFLRDVASEQRKNRGERSGVAIRLLWVIDDDASLPRKLQRELKSLNVFILAHSINANCFTDESVVLAPNFHFIKRDGFKLFLRNLREREIPFDERKSDVFWRGSTSGMSTKCEVEESTRVDGNERVTACVKLPRVRAVQSSINVPWLDLEITRRVQSCRGQKNVRISPRVSEQHWITHKGILEIDGNVDAWGNRWRMESGSVLFLVKSNFKHYYSDKLVDGIHYIGISGDLHDLVEKTKIITNTDGESLTKLRDITANARALMQEFTYERVVKGVSHRLNELALGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAE6</accession>
    <name>A4SAE6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422372.1">
        <property type="nucleotide sequence ID" value="XM_001422335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAE6"/>
    <dbReference type="STRING" id="436017.A4SAE6"/>
    <dbReference type="GeneID" id="5006480"/>
    <dbReference type="Gramene" id="ABP00689">
        <property type="protein sequence ID" value="ABP00689"/>
        <property type="gene ID" value="OSTLU_28542"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28542"/>
    <dbReference type="eggNOG" id="ENOG502RHWX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2390062_0_0_1"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF113">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="22"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="94" mass="10333" checksum="54F1DFEFD20D64CE" modified="2007-05-15" version="1">MLRESETPYLVDLTCGSQGNVAVGELITAVAEAIDADVIVMATHNRGALARFFVGSVANFCLRNATMPVVLLRPGEYALDRKRSHHRVLIDRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAJ3</accession>
    <name>A4SAJ3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sphingomyelin phosphodiesterase 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Gramene" id="ABP00716">
        <property type="protein sequence ID" value="ABP00716"/>
        <property type="gene ID" value="OSTLU_94029"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94029"/>
    <dbReference type="eggNOG" id="ENOG502QSXW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31801">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31801:SF1">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="948"/>
        </location>
    </feature>
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        <location>
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            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="540"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
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            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="58"/>
        </location>
    </feature>
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            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="954" mass="104867" checksum="F78983D4F44A4E41" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAQ8</accession>
    <name>A4SAQ8_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94053</name>
    </gene>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAQ8"/>
    <dbReference type="GeneID" id="5006535"/>
    <dbReference type="Gramene" id="ABP00794">
        <property type="protein sequence ID" value="ABP00794"/>
        <property type="gene ID" value="OSTLU_94053"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94053"/>
    <dbReference type="HOGENOM" id="CLU_079214_0_0_1"/>
    <dbReference type="OMA" id="RARCEWA"/>
    <dbReference type="OrthoDB" id="10488117at2759"/>
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        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
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    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="306" mass="32890" checksum="33891F89467A117D" modified="2007-05-15" version="1">MSFKTFTTTPSRAHGATARATASSTRIGQKSARPAAARNRGATRAHARDDAPASEGRTVDALNKLSSLYESESERDERIRATQRERDAMEGLGLADAFKTAKRGSKTRRDFARKRTYGVTRTSFGAVVELGCAAEVVYGYWTTPAALAETLPELEKCEAAADGGRARCEWVYAFGDIRKKHGRTAVDAVERHLSVVKATELEAGSSVRYEATAGMPVGADIAVTSTGANSCTLDIDAWVHLPLSLTHTSGTMAVALDVQDKFYQALAAFKTLCDEGDAAARLEEIKSSARDACAVGDRPNFQFRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAR3</accession>
    <name>A4SAR3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AEC family transporter: auxin efflux</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_25832</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAR3"/>
    <dbReference type="STRING" id="436017.A4SAR3"/>
    <dbReference type="GeneID" id="5006539"/>
    <dbReference type="Gramene" id="ABP00969">
        <property type="protein sequence ID" value="ABP00969"/>
        <property type="gene ID" value="OSTLU_25832"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25832"/>
    <dbReference type="eggNOG" id="ENOG502S5VV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_450091_0_0_1"/>
    <dbReference type="OMA" id="RMYVLAI"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080162">
        <property type="term" value="P:endoplasmic reticulum to cytosol auxin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045033">
        <property type="entry name" value="PILS1/3/4/5/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31651">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31651:SF36">
        <property type="entry name" value="AUXIN EFFLUX CARRIER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="508"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="548"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="588"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="607" mass="66310" checksum="CD37C6938A377B46" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB21</accession>
    <name>A4SB21_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422540.1">
        <property type="nucleotide sequence ID" value="XM_001422503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB21"/>
    <dbReference type="GeneID" id="5006598"/>
    <dbReference type="Gramene" id="ABP00857">
        <property type="protein sequence ID" value="ABP00857"/>
        <property type="gene ID" value="OSTLU_29459"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29459"/>
    <dbReference type="HOGENOM" id="CLU_2562510_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673318" evidence="1">
        <location>
            <begin position="21"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="82" mass="9758" checksum="0076FD681010998D" modified="2007-05-15" version="1">MTIRSAISGAFLFLARLALACSYWFSAKKPRTLLESFQRATFEVSTYRGDPEYMTYRHEAEYMRREAERLSYKLACVRRRCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBK5</accession>
    <name>A4SBK5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Isopropylmalate dehydrogenase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_29641</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422788.1">
        <property type="nucleotide sequence ID" value="XM_001422751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBK5"/>
    <dbReference type="STRING" id="436017.A4SBK5"/>
    <dbReference type="GeneID" id="5006938"/>
    <dbReference type="Gramene" id="ABP01147">
        <property type="protein sequence ID" value="ABP01147"/>
        <property type="gene ID" value="OSTLU_29641"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29641"/>
    <dbReference type="eggNOG" id="KOG1526">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023296_1_1_1"/>
    <dbReference type="OMA" id="HGTVQRH"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="BRENDA" id="1.1.1.41">
        <property type="organism ID" value="11579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006739">
        <property type="term" value="P:NADP+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822:SF21">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="NADP-SPECIFIC ISOCITRATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="9">
        <location>
            <begin position="7"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP01147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="409" mass="45449" checksum="E9352D227DE16CFA" modified="2007-05-15" version="1">MSANASKITAAPMVYVRGEEMTAYVMDLIRAKWIEPRVDTTAWREFDLRAKNRDDTEDQVLRDVIEAGKAVKAIFKEPTVTPTADQVKRLGLRKSWGSPNGAMRRGWNGITISRDTIHIDGVELGYKKPVFFERHAVGGEYAAGYKNVGKGTLVTTFTPSEGPDAGKPVEVDSRTITDNEAAVVTYHNPYDNVHELARFFFGRCLEAKITPYVVTKKTVFKWQEPFWQIMKKVFDEEYKSKFVDAGVMKSGDELVHLLSDAATMKLVQWRQGGFGMAAHNYDGDVLTDELAQIHKSPGFITSNLVGVDENGTLIKEFEASHGTVADMDEARLRGEETSLNPLGMVEGLIGAMNHAADVHNVDKERTLAFTAKMRAVIHQLFREGKGTRDLSGPSGLTTEQFVDAVAERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQJ5</accession>
    <name>A4RQJ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_13600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415400.1">
        <property type="nucleotide sequence ID" value="XM_001415363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQJ5"/>
    <dbReference type="STRING" id="436017.A4RQJ5"/>
    <dbReference type="MEROPS" id="S41.002"/>
    <dbReference type="GeneID" id="5000049"/>
    <dbReference type="Gramene" id="ABO93692">
        <property type="protein sequence ID" value="ABO93692"/>
        <property type="gene ID" value="OSTLU_13600"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13600"/>
    <dbReference type="eggNOG" id="ENOG502QSWI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017295_0_0_1"/>
    <dbReference type="OMA" id="EDAFCSC"/>
    <dbReference type="OrthoDB" id="43580at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06782">
        <property type="entry name" value="cpPDZ_CPP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000063">
        <property type="entry name" value="Peptidase, S41 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.44">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060:SF7">
        <property type="entry name" value="CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060">
        <property type="entry name" value="TAIL-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="88"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="389" mass="41208" checksum="BF1CF60BFCE3FA07" modified="2007-05-15" version="1">MHAAAATRASAITENQMLYLEAWRAVDKAYVDKTFNGNNWFKLRERGLKTADLDDTEATYGTIREMLGKLGDPFTQFLEPEKYASVTDRTMKADVSGVGVEMGFGDDAKVVVVAPTPGGPSAEAGVKAKDFIVAVDGAATRGKSLYEVADELQGPQGSKVTLTLERDGKTRDVAVQRKRYTVVPVTSATCEVKGDKKIGYVKLSAFNQVSGAKTKEALAALKADGVDVFVLDLRDNVGGLFPGALEIAKAFMNEGTIVYIADSNGERDVFQADRTALDAATPLKLLVNKGTASASEVLSGALQDNKRAIVLGEQTFGKGLIQTLVPLSDGSAVSVTVAQYRTPNGTDINKIGITPDAPLPLDASGADIVPSNAADFCAYAREAPELFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQS7</accession>
    <name>A4RQS7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415438.1">
        <property type="nucleotide sequence ID" value="XM_001415401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQS7"/>
    <dbReference type="GeneID" id="4999607"/>
    <dbReference type="Gramene" id="ABO93730">
        <property type="protein sequence ID" value="ABO93730"/>
        <property type="gene ID" value="OSTLU_28766"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28766"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1809429_0_0_1"/>
    <dbReference type="OrthoDB" id="515079at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45676">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="97"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="143" mass="16568" checksum="482470EC612C8602" modified="2007-05-15" version="1">MVKNEALLARERECAVRDEIWATRLEDDETTGYDFEATLEELWMDWWWKMSRGERLSAEKASVMDMLTAIVNGTSSRDIETGVRRVSVAEASESSDCPVCLEDDDSRADIVRLTRCEHTFHIDCIAPWLQRHKTCPKCRARVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQT6</accession>
    <name>A4RQT6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS family transporter: acetyl-CoA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_13668</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415443.1">
        <property type="nucleotide sequence ID" value="XM_001415406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQT6"/>
    <dbReference type="GeneID" id="4999790"/>
    <dbReference type="Gramene" id="ABO93735">
        <property type="protein sequence ID" value="ABO93735"/>
        <property type="gene ID" value="OSTLU_13668"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13668"/>
    <dbReference type="eggNOG" id="KOG3574">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020502_1_0_1"/>
    <dbReference type="OMA" id="RRKSWIM"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="438" mass="48175" checksum="1A12AC9E52F0F51A" modified="2007-05-15" version="1">MGLSSSVGFILQERGASYGDQGVFSLASWPFSLKVLWAPVVDAVYVKSFGQRRTWVMPLQAIVGCTLLFLANALGELISADGSDVKTLTWTFFWLYLLLASQDIAVDGWALTMLSEKNVGLASTCNAIGQMVGFFVCFTGFLVLNSYGVDLGAFISFWGYVFIASSVFVYATKEVRCETQMSVKKAYAQAFSILRLPAVLKLSAVLLTRFVAFSASETLTTLKLLEKGVPKTHIATMSALMTPLNLAMPMLTRKWTAGARPLDTITKTWVWRGVACAFAALLVFYAPDVTSSGTIPYGYYAFLFAWLSVYSAFSNAHFISFMAFYNRVSDADMGGTYMTILNTVSNLGAKWMESVTLFTIDRVNTNVCVAKGTREIIGSCATDALKAACKGKCATTDTPYYIVVMLSPVIAYAWLRLTRKTIDWLSQAQKSHWRVKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR13</accession>
    <name>A4RR13_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plant heme peroxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28854</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415486.1">
        <property type="nucleotide sequence ID" value="XM_001415449.1"/>
    </dbReference>
    <dbReference type="GeneID" id="4999946"/>
    <dbReference type="Gramene" id="ABO93778">
        <property type="protein sequence ID" value="ABO93778"/>
        <property type="gene ID" value="OSTLU_28854"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28854"/>
    <dbReference type="HOGENOM" id="CLU_254447_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="5">
        <location>
            <begin position="240"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="697"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="824"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="950"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="708"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="829"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="864"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="953"/>
            <end position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1399" mass="152662" checksum="89B891208266BBDC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRH6</accession>
    <name>A4RRH6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_29020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415903.1">
        <property type="nucleotide sequence ID" value="XM_001415866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRH6"/>
    <dbReference type="STRING" id="436017.A4RRH6"/>
    <dbReference type="GeneID" id="4999852"/>
    <dbReference type="Gramene" id="ABO94195">
        <property type="protein sequence ID" value="ABO94195"/>
        <property type="gene ID" value="OSTLU_29020"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29020"/>
    <dbReference type="eggNOG" id="KOG1414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1742968_0_0_1"/>
    <dbReference type="OrthoDB" id="674948at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14704">
        <property type="entry name" value="bZIP_HY5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.490">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044280">
        <property type="entry name" value="Hac1/HY5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46714">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46714:SF6">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="9">
        <location>
            <begin position="82"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="96"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="162" mass="17531" checksum="C062A4078C1089A4" modified="2007-05-15" version="1">MTAGSGGSGRAKRAGAGARGSGTPPSGAVSKPTARGGRAAANQGGFGMGYVGRNSMHIPHGNTALSVKADEERLNTITDEKERKRLKRLLRNRVSAQQARERKKAYLASLEQTEAQKANRLHELENRVTTLERENQMLRQVIQTVTRRAVPPNASDFQVPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRV0</accession>
    <name>A4RRV0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_86258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415966.1">
        <property type="nucleotide sequence ID" value="XM_001415929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRV0"/>
    <dbReference type="STRING" id="436017.A4RRV0"/>
    <dbReference type="GeneID" id="4999932"/>
    <dbReference type="KEGG" id="olu:OSTLU_86258"/>
    <dbReference type="eggNOG" id="KOG4151">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1063154_0_0_1"/>
    <dbReference type="OMA" id="WEEDTHA"/>
    <dbReference type="OrthoDB" id="2942533at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044517">
        <property type="entry name" value="PHOX1-4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46183">
        <property type="entry name" value="PROTEIN CLMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46183:SF8">
        <property type="entry name" value="PROTEIN CLMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="262" mass="28471" checksum="76DC2EC8B0F7164F" modified="2007-05-15" version="1" fragment="single">LSNDLASGTSLTDEEAKEIRDAAIEKFQACAAATIFNWGNVHMCEARKKMDGGREPAKEQGGPPGSAIAIADEFDEVERLIGLAKERFEEAIVIKPDHHDSHIALAQRRYERSRLLSAAAGMSGDEGKVAKGHDAKKRIAEAEAEFVGAVADYKAVFATLPDEVPREKTEEEKAAFQALVDEAVARGDEPPTDEEPSTKGQVRVMLGNTLFEQSQLAARLGKEWKSMLDEALENFHEAGCAQEDIDNAVSMHYGTRMTAGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS19</accession>
    <name>A4RS19_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_5468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416004.1">
        <property type="nucleotide sequence ID" value="XM_001415967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS19"/>
    <dbReference type="GeneID" id="4999864"/>
    <dbReference type="Gramene" id="ABO94296">
        <property type="protein sequence ID" value="ABO94296"/>
        <property type="gene ID" value="OSTLU_5468"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5468"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_1"/>
    <dbReference type="OMA" id="HYAARDR"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="292" mass="31882" checksum="FF59E839DEDCA678" modified="2007-05-15" version="1" fragment="single">EVVVITGANTGLGYETAKAAAKAGRRVVAAVRDEARGERAKTRVLAAVPEAKVDVMLVDLADFESVRAFARAFEAKYDRLDALVNNSGVMAPPSRSETKDGNELQMQVNHLGHFLLTSLLLDTMVNTPSDDKRIVNLSSIAHNFGTLDFHNVNSEGVFGYPFLGWATYGRTKMANIMFTFELDRRLKAKGVTNVAVNAVHPGVVDTELNRSLSLDFYPQLKAAGKLITPEQGARGQIALAMDEKYRGVSGVYVSELSDDGKPGVHEPKRANERAYDAEAWARLWKDSVKLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS82</accession>
    <name>A4RS82_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DMT family transporter: UDP-galactose/UDP-glucose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_29277</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416031.1">
        <property type="nucleotide sequence ID" value="XM_001415994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS82"/>
    <dbReference type="GeneID" id="4999971"/>
    <dbReference type="Gramene" id="ABO94323">
        <property type="protein sequence ID" value="ABO94323"/>
        <property type="gene ID" value="OSTLU_29277"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29277"/>
    <dbReference type="eggNOG" id="KOG1581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036019_3_0_1"/>
    <dbReference type="OMA" id="KFENTQF"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF13">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="356" mass="38761" checksum="2E4F4842D35B2783" modified="2007-05-15" version="1">MTSRGENGVLGVLCTPKALKIIGCVVGVVGSLVVYGILQERIMTRPYGDDGEEEFFKFSVFLVLNNRLLAVCAAACILVAIKGAVRPVAPIYSYATVSASNVVATTCQYEALKYVSFPVQTLGKCAKMIPVMIWGFAINQRRYDAADMLVAAFITAGCTIFALYGDVTNKHVSSGGDTSWYGGVLMLGYLGFDGFTSTFQDKLFKGYHMETYNQMVWVNLCSAAISLFWLLSDSSLTEAFNFIGRHPGVMGDVIILSTAAMLGQLCILYTIREFGALLFATIMTTRQFISILLSCIIFMHPLTLPQWGGTCMVFGALYYNAFLKAARKGSKKEITIVSDDAKSGEKENLISKDGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSD9</accession>
    <name>A4RSD9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_14362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416504.1">
        <property type="nucleotide sequence ID" value="XM_001416467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSD9"/>
    <dbReference type="GeneID" id="5000427"/>
    <dbReference type="Gramene" id="ABO94797">
        <property type="protein sequence ID" value="ABO94797"/>
        <property type="gene ID" value="OSTLU_14362"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14362"/>
    <dbReference type="HOGENOM" id="CLU_848340_0_0_1"/>
    <dbReference type="OMA" id="DRRVSEC"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="328" mass="36189" checksum="47798879F679E68B" modified="2007-05-15" version="1">MAKGEPTKATVGEALRALDARARRMEAEARRERDARARDRDALARVTESVDALAATFREAMEAISCDHDAWTRERREIKAAVEVAARAATTAATRAEARERDAERARAEALAIDARVSEGLRYVKDVRDEFVAVERVIQEAKERTRELEARDVARARAVEEFERRARAADALLRDEIETVRACSLHAETAASKAEEIGGLASDVRELAKWSKETAAHQNRRLAALERETSHEGGDKENGAARRKGELATSVKATELALKAQQTRLTALEEKSALRARRDAAVKADVDVVKRALGEHHDLLAKIRDTLDTELGPEATLGPASSAFARFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSH6</accession>
    <name>A4RSH6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416246.1">
        <property type="nucleotide sequence ID" value="XM_001416209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSH6"/>
    <dbReference type="GeneID" id="5000551"/>
    <dbReference type="Gramene" id="ABO94539">
        <property type="protein sequence ID" value="ABO94539"/>
        <property type="gene ID" value="OSTLU_30251"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30251"/>
    <dbReference type="HOGENOM" id="CLU_2626419_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="78" mass="9014" checksum="BDFB0421B009AD1E" modified="2007-05-15" version="1">MSSHCLRIRGGLVRVVTLFAHTRWFGTCRHTVCAYEVVWYVSSYCLRIRGGLVHVVTLFAHTRWFGTCHHTVCAYEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSL5</accession>
    <name>A4RSL5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Thymidine kinase</fullName>
            <ecNumber evidence="2 10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_14315</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>thymidine + ATP = dTMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 10"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416221.1">
        <property type="nucleotide sequence ID" value="XM_001416184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSL5"/>
    <dbReference type="STRING" id="436017.A4RSL5"/>
    <dbReference type="GeneID" id="5000414"/>
    <dbReference type="Gramene" id="ABO94514">
        <property type="protein sequence ID" value="ABO94514"/>
        <property type="gene ID" value="OSTLU_14315"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14315"/>
    <dbReference type="eggNOG" id="KOG3125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064400_1_1_1"/>
    <dbReference type="OrthoDB" id="439028at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046104">
        <property type="term" value="P:thymidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="THYMIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441:SF0">
        <property type="entry name" value="THYMIDINE KINASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="166"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="21305" checksum="C50E5202F7B5EA0A" modified="2007-05-15" version="1">MFAGKTTHLMRCVERERARGRTVFVIKSELDVERFGEDARDALIAHDGKRVRFDASDDGGRVRAVRTLDAAGLGADAAACDAADVVAVDEAQFMGDLAPFARRCAEELGQTVYVCGLDGDYRRERFGGVLDLIPLCDTVTRLRGTCAECGDESLFSRRVEASEDVVRVGGRDKYAPVCRACYVAASTRERGSASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSM6</accession>
    <name>A4RSM6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_24119</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416217.1">
        <property type="nucleotide sequence ID" value="XM_001416180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSM6"/>
    <dbReference type="STRING" id="436017.A4RSM6"/>
    <dbReference type="GeneID" id="5000261"/>
    <dbReference type="Gramene" id="ABO94510">
        <property type="protein sequence ID" value="ABO94510"/>
        <property type="gene ID" value="OSTLU_24119"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24119"/>
    <dbReference type="eggNOG" id="KOG0087">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_23_1_1"/>
    <dbReference type="OMA" id="AHANIKQ"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000067">
        <property type="entry name" value="ras-related protein RABA1f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="202" mass="22260" checksum="AE8AB75948FF9E41" modified="2007-05-15" version="1">MSGETDDSYDYLFKIVLVGDSGVGKSNLLSRFTRNEFCLESKSTIGVEFATRTIELQNKIIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDVTSGDTYDNIEKWLSELRDHADASIVIMLVGNKCDLEHLRVTEAATAQQFAEKEGLMFIETSALNATNVEHAFIDSLGRVYDVVSKLKMACTPSQSAAASLVCRTVSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSQ9</accession>
    <name>A4RSQ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ClpR3</name>
        <name evidence="4" type="ORF">OSTLU_30150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416446.1">
        <property type="nucleotide sequence ID" value="XM_001416409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSQ9"/>
    <dbReference type="STRING" id="436017.A4RSQ9"/>
    <dbReference type="GeneID" id="5000326"/>
    <dbReference type="Gramene" id="ABO94739">
        <property type="protein sequence ID" value="ABO94739"/>
        <property type="gene ID" value="OSTLU_30150"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30150"/>
    <dbReference type="eggNOG" id="KOG0840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_5_0_1"/>
    <dbReference type="OMA" id="EFLYLQW"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF6">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT-RELATED PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="28"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="33397" checksum="CF7BADB97BA3C6D9" modified="2007-05-15" version="1">MKSTYVVSSVTCSARAARVAHGDHLRSAANRRVGAKTAPQHLERVTTTSRRRPRTIHAHGRPGAAISNAYASPQASNSPASANPGTSYSEHKPKTPPPDLPSLLLDSRIVYIGMPLVPAVTELIVSELLYLQYTDQKKPCYIYINSTGCTRADGEVVGFETEATAIFDTMKYIGNEIYTVGTGVAIGQACMLLSAGDKGKRYMTPHATAMLHQPRVPSTGERQATELNIKWRETLAQKKSLLDILSQTTGHSVAKLDKDMQRPLYMTAKDAIEYGIVDKVIERESNAIADVMSASAWDSAAGLVQKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RST0</accession>
    <name>A4RST0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sojo-related cytoskeleton protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Soj</name>
        <name evidence="8" type="ORF">OSTLU_119584</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416191.1">
        <property type="nucleotide sequence ID" value="XM_001416154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RST0"/>
    <dbReference type="GeneID" id="5000430"/>
    <dbReference type="Gramene" id="ABO94484">
        <property type="protein sequence ID" value="ABO94484"/>
        <property type="gene ID" value="OSTLU_119584"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119584"/>
    <dbReference type="HOGENOM" id="CLU_781550_0_0_1"/>
    <dbReference type="OMA" id="MRIATIR"/>
    <dbReference type="OrthoDB" id="10603117at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
        <property type="entry name" value="TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID component TAF4 C-terminal" evidence="7">
        <location>
            <begin position="107"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="370" mass="41292" checksum="8B4F600CBD0AF0A9" modified="2007-05-15" version="1">MGVACGPSRGEGDHGPQEQARQVPSYVSLSEVLRLVREGHVNGDDIMRLASLYLSMKSKRASAKEILSALFSHAHGGEILRVISAVVVGAKSLQSEGFVNSQGGNTLLISHAQSKTNHVNQRAKQITQKVVFDQQRLSKRIASKLRSRHPGMHVDPASFELFGEAIRQRIRHISKDLMRIATIRHMSSIIAKNSKAERVTPRGKIRDINLTLMQSTSARREQERQKLLQLGDQSNKRKRQSSDDEFDEELRTRAEKARTEEEERRLADAANEATRSALGDAKYLKWFAHGKNVQKTTELNPRVSSAVTSKQTTRAEATEKASKTGLETHDSKISFVDVICVLKSEKAFNGILPRLFHTKNLLLFNVGNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT70</accession>
    <name>A4RT70_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prostaglandin E synthase 2</fullName>
            <ecNumber evidence="3">5.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Microsomal prostaglandin E synthase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">OSTLU_29981</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>prostaglandin H2 = (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde</text>
            <dbReference type="Rhea" id="RHEA:48644"/>
            <dbReference type="ChEBI" id="CHEBI:57405"/>
            <dbReference type="ChEBI" id="CHEBI:90694"/>
            <dbReference type="ChEBI" id="CHEBI:566274"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:48645"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>prostaglandin H2 = prostaglandin E2</text>
            <dbReference type="Rhea" id="RHEA:12893"/>
            <dbReference type="ChEBI" id="CHEBI:57405"/>
            <dbReference type="ChEBI" id="CHEBI:606564"/>
            <dbReference type="EC" id="5.3.99.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:12894"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; prostaglandin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="18">Endomembrane system</location>
            <topology evidence="18">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.99.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416367.1">
        <property type="nucleotide sequence ID" value="XM_001416330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT70"/>
    <dbReference type="STRING" id="436017.A4RT70"/>
    <dbReference type="GeneID" id="5000308"/>
    <dbReference type="Gramene" id="ABO94660">
        <property type="protein sequence ID" value="ABO94660"/>
        <property type="gene ID" value="OSTLU_29981"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29981"/>
    <dbReference type="eggNOG" id="KOG3029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_0_2_1"/>
    <dbReference type="OMA" id="DYCLTEG"/>
    <dbReference type="OrthoDB" id="423541at2759"/>
    <dbReference type="UniPathway" id="UPA00662"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050220">
        <property type="term" value="F:prostaglandin-E synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001516">
        <property type="term" value="P:prostaglandin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03197">
        <property type="entry name" value="GST_C_mPGES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034334">
        <property type="entry name" value="PGES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034335">
        <property type="entry name" value="PGES2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12782">
        <property type="entry name" value="MICROSOMAL PROSTAGLANDIN E SYNTHASE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12782:SF5">
        <property type="entry name" value="PROSTAGLANDIN E SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01182">
        <property type="entry name" value="Prostaglandin_E_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01203">
        <property type="entry name" value="Prostaglandin_E_synthase_like1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0643">Prostaglandin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0644">Prostaglandin metabolism</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="GST N-terminal" evidence="20">
        <location>
            <begin position="62"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ABO94660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="311" mass="33909" checksum="86AC4F620873F465" modified="2007-05-15" version="1">MTHRASTAATTARASTRTRAGTAATATAAAAAAAALAATTAGREASAEAPRTSPADAALGGARVTLYQYDVCPFCNKVKAFLDYHGTPYDVVEVNPMTKGELGWVEDGWKKVPIVTVGDEKLNDSSAIIAELTKRFDASGSSANAGAWFGAKKTKAYLEREATWTKWVDERFVHVLTPNIYRTWAEAVKSFDYITKRGNFGYFERESARWVGAASMYVIAHRVLKKRHGIEDERADLYAECDKFVDEAVGSRKFCGGDAPNNADLCVFGVLRAVKTFETFADVMANTSIRPWYERMEKAVGPATRTDGLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT96</accession>
    <name>A4RT96_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_36182</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416352.1">
        <property type="nucleotide sequence ID" value="XM_001416315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT96"/>
    <dbReference type="STRING" id="436017.A4RT96"/>
    <dbReference type="GeneID" id="5000152"/>
    <dbReference type="Gramene" id="ABO94645">
        <property type="protein sequence ID" value="ABO94645"/>
        <property type="gene ID" value="OSTLU_36182"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36182"/>
    <dbReference type="eggNOG" id="KOG0733">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_8_3_1"/>
    <dbReference type="OMA" id="YYYFGKK"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000661">
        <property type="entry name" value="calmodulin-interacting protein 111 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001985">
        <property type="entry name" value="Chromosome 9, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="41"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="335"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="567" mass="60997" checksum="9AA86794F3164306" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT97</accession>
    <name>A4RT97_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ferritin</fullName>
            <ecNumber evidence="13">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_7252</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 13">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ferritin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="13"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416353.1">
        <property type="nucleotide sequence ID" value="XM_001416316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT97"/>
    <dbReference type="STRING" id="436017.A4RT97"/>
    <dbReference type="GeneID" id="5000377"/>
    <dbReference type="Gramene" id="ABO94646">
        <property type="protein sequence ID" value="ABO94646"/>
        <property type="gene ID" value="OSTLU_7252"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7252"/>
    <dbReference type="eggNOG" id="KOG2332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065681_4_0_1"/>
    <dbReference type="OMA" id="FFLKASM"/>
    <dbReference type="OrthoDB" id="186462at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01056">
        <property type="entry name" value="Euk_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.10:FF:000024">
        <property type="entry name" value="Ferritin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431:SF75">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="3 13" id="KW-0409">Iron storage</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="14">
        <location>
            <begin position="10"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601519-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO94646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="178" mass="20293" checksum="0A95E8FAD0C7554E" modified="2007-05-15" version="1" fragment="single">QSVEYSFARSGFANECELALNAQINVEYNVSYIYHAMWAYFSRDNVALKGFAEHFKREALEEREHAEQLMEYMNLRGGRVELQQLLPPQSEYDHPEKGCALYALELSLSLEKLNNDKLCELHRVADDAGDAHMCDFLEGEMLAPQVESVREVSEMVATLLRMGPPGDGMAAWHFDQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTR3</accession>
    <name>A4RTR3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_30355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0677 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416539.1">
        <property type="nucleotide sequence ID" value="XM_001416502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTR3"/>
    <dbReference type="STRING" id="436017.A4RTR3"/>
    <dbReference type="GeneID" id="5001006"/>
    <dbReference type="Gramene" id="ABO94832">
        <property type="protein sequence ID" value="ABO94832"/>
        <property type="gene ID" value="OSTLU_30355"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30355"/>
    <dbReference type="eggNOG" id="ENOG502QRNU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056160_3_1_1"/>
    <dbReference type="OrthoDB" id="498921at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011610">
        <property type="entry name" value="SAM_mthyl_Trfase_ML2640-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00027">
        <property type="entry name" value="mthyl_TIGR00027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE YKTD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619:SF2">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="28762" checksum="9ED1279F152F2AF9" modified="2007-05-15" version="1">MARADARRREDGDKGRIAVRTKFFDDFVTAAAGKMASARGETTQVVLLGAGYDTRSWRLRAASEEARERTSVYEVDVEEVLARKREVVSDAPLTLGAERREVASDIAKDDWVAALKAAGMSTELPTVWVLEGLLYYLSPRCAKKTLALCHRSCGPGSVVAVSVVNAPSLRRARREPFKSKFLRVFGRAAPKTARQCWKSSCDVPPEAYFAPWRLDACAQLGDGALHYGRWTGAPPTPFATDRKSYRRDPTPRTFYVAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTR7</accession>
    <name>A4RTR7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Class I SAM-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416542.1">
        <property type="nucleotide sequence ID" value="XM_001416505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTR7"/>
    <dbReference type="GeneID" id="5000651"/>
    <dbReference type="Gramene" id="ABO94835">
        <property type="protein sequence ID" value="ABO94835"/>
        <property type="gene ID" value="OSTLU_30359"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30359"/>
    <dbReference type="eggNOG" id="ENOG502SAKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_928607_0_0_1"/>
    <dbReference type="OMA" id="NDASAHE"/>
    <dbReference type="OrthoDB" id="10058237at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="26691" checksum="6768FAE48D4E2F74" modified="2007-05-15" version="1">MVTAMLSNYQHDDMSLFGAVGELGVHHGRFTSCLFITADASEALVAVDVFEKQNLNVDGSGHGSYHRFMQAMSHLGLRFRDFALLHKGSTTDLATDWLSKHHIDPFRLVSVDAGHTAELTFRDLGAVACNLAPGGVIVVDDFFHPHWTGVTEGLFQYLTRGAVRLYPFLVCAGKVYLTNDASAHEAYARRLQSDAAVGEFFKSDSAEFHGSTYHEMAGVHFLNCPNVDRARVTARWLDEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTV1</accession>
    <name>A4RTV1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="4">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_33820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="4"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416560.1">
        <property type="nucleotide sequence ID" value="XM_001416523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTV1"/>
    <dbReference type="STRING" id="436017.A4RTV1"/>
    <dbReference type="GeneID" id="5000725"/>
    <dbReference type="Gramene" id="ABO94853">
        <property type="protein sequence ID" value="ABO94853"/>
        <property type="gene ID" value="OSTLU_33820"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33820"/>
    <dbReference type="eggNOG" id="KOG1557">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031243_0_1_1"/>
    <dbReference type="OMA" id="NFVANHA"/>
    <dbReference type="OrthoDB" id="36455at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000140">
        <property type="entry name" value="Fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033379">
        <property type="entry name" value="FrucBisAld_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="337" mass="35573" checksum="01F65E106AD250F6" modified="2007-05-15" version="1">MSFADELRATALALSAPGKGILAADESTGTIGKRLASIGVENAIENRVALRELLFSAPGFEKYVSGVILFDETLRSTGKSGTSFAEMLRSRGVTPGIKVDAGTRALDASPNETFTQGLDGLAERCEEYYAMGARFAKWRAVLTIDEAKGLPSALALAENANALARYASACQSRGLVPIVEPEILMDGAHGIEVCGAVTRRVLDAVFSALRLHGVQLDGMILKPNMVTPGASAKTSANVDAEVARATVAALCDTVPPSVPGILFLSGGQSEEEATERLRLMNTTQKADRAPWTLSFSYGRALQASCLKAWGGKSENVSAAQAAFLDRCKSNSEASIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTV8</accession>
    <name>A4RTV8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_34199</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416852.1">
        <property type="nucleotide sequence ID" value="XM_001416815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTV8"/>
    <dbReference type="GeneID" id="5000688"/>
    <dbReference type="Gramene" id="ABO95145">
        <property type="protein sequence ID" value="ABO95145"/>
        <property type="gene ID" value="OSTLU_34199"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34199"/>
    <dbReference type="eggNOG" id="KOG4308">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017147_4_0_1"/>
    <dbReference type="OMA" id="CDAVKTN"/>
    <dbReference type="OrthoDB" id="341587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="471" mass="49899" checksum="26E1B4D5F36B44C6" modified="2007-05-15" version="1">MDGPVSVAPKQQQQQKKIITREAKRMLRDVMDELRRVQTVDASGKNLGDEGTCFIAEAFAYNNVATCVDMSANGIGVEGVTALCEALKCNDTLTMLSLASNSLGDEGAKVLADYLKTDEKITTINLNACSIGDEGARAIAEALKTNTTITSLEMNNNMVDYEGSGALAQAFAQNSTVELLALSGNYVGTLGAAALGAAFKENTGLRSLQLNGNDIGNEGCIKLCEGLAARKDKINNLDLGNNSIGPEAGPALRDYLKDDDALTHLNLYMNELANDGCAAVAESLKDNKKIELLDIGGNNIGAFGAEKLAEALRDNESLVTLELGYNPIGVPGGKALAETVKFHGKLNTMRMGWCKIGKEGGFAFADAIKYSSSLAVLDLRGNDLGDDGVAALAQSLGVVNEVLTNLDLGYNEIKDKGAFALAQAIKNNADGSLQTLSINNNYLTKFGEVALTEAVELVQEMNADRDLYVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUM4</accession>
    <name>A4RUM4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FBP11-1</name>
        <name evidence="8" type="ORF">OSTLU_30671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416984.1">
        <property type="nucleotide sequence ID" value="XM_001416947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUM4"/>
    <dbReference type="STRING" id="436017.A4RUM4"/>
    <dbReference type="GeneID" id="5000602"/>
    <dbReference type="Gramene" id="ABO95277">
        <property type="protein sequence ID" value="ABO95277"/>
        <property type="gene ID" value="OSTLU_30671"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30671"/>
    <dbReference type="eggNOG" id="KOG0543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_7_3_1"/>
    <dbReference type="OMA" id="GDKWELV"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672896" description="peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="73"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="16961" checksum="E6B1EA16FA4E3A60" modified="2007-05-15" version="1">MARGRRSTTLALVLAVIALIGCAFVGGMADAKSDGAAFLAANKLKPGVVELPSGLQYRVLKSGPEGGPSPSKSTPCSCHYSGKNIQGEEFDSSYKRGQPTTFAPNQVISGWTEAMQLMKEGDKWELVIPSELAYGKSSPTPLIKPDSVLIFEMELVKVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUS4</accession>
    <name>A4RUS4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gem-associated protein 5 TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416721.1">
        <property type="nucleotide sequence ID" value="XM_001416684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUS4"/>
    <dbReference type="STRING" id="436017.A4RUS4"/>
    <dbReference type="GeneID" id="5000934"/>
    <dbReference type="Gramene" id="ABO95014">
        <property type="protein sequence ID" value="ABO95014"/>
        <property type="gene ID" value="OSTLU_30722"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30722"/>
    <dbReference type="eggNOG" id="ENOG502QPYZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004491_0_1_1"/>
    <dbReference type="OMA" id="DYAFQMM"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052640">
        <property type="entry name" value="Gemin-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056421">
        <property type="entry name" value="TPR_GEMI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362:SF1">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23774">
        <property type="entry name" value="TPR_GEMI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="653"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Gem-associated protein 5 TPR" evidence="2">
        <location>
            <begin position="791"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1057" mass="112388" checksum="1E3A9151F903B8D9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVD9</accession>
    <name>A4RVD9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">procollagen-proline 4-dioxygenase</fullName>
            <ecNumber evidence="4">1.14.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_37480</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the P4HA family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417405.1">
        <property type="nucleotide sequence ID" value="XM_001417368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVD9"/>
    <dbReference type="STRING" id="436017.A4RVD9"/>
    <dbReference type="GeneID" id="5001195"/>
    <dbReference type="Gramene" id="ABO95698">
        <property type="protein sequence ID" value="ABO95698"/>
        <property type="gene ID" value="OSTLU_37480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37480"/>
    <dbReference type="eggNOG" id="KOG1591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058132_5_0_1"/>
    <dbReference type="OMA" id="ETDQGYC"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000002">
        <property type="entry name" value="Prolyl 4-hydroxylase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF238">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="15">
        <location>
            <begin position="124"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="16">
        <location>
            <begin position="282"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO95698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="36384" checksum="30C1F21CCB7C3639" modified="2007-05-15" version="1">MDDLALANTIRFDAANGTRPLSLYGRAALLNALPGFPETPPLVLSATQPKAYLLRNFLSAEECDHLMKLAKRELAPSTVVGEAGDSVPSDIRTSAGMFLRKGQDKIVKAIEERIARLSGTPVDNGEGMQILRYDVGQKYDPHFDYFHDKVNPAPKRGGQRLATMLIYLVDTDKGGETTFPNAKLPQSFEADEPENPFASHIEHTDCAKKGIPVKSVRGDAILFFSMTQDGVLDRGSLHGACPVIEGQKWTAVKWIRVGKFDGNYQEEIPMPKLSRRTDEEPCVDDWDECAKWASQGWCELNPEFMTTADSARDSQSAACAKSCGLCNRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVE5</accession>
    <name>A4RVE5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-acyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_9699</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417121.1">
        <property type="nucleotide sequence ID" value="XM_001417084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVE5"/>
    <dbReference type="STRING" id="436017.A4RVE5"/>
    <dbReference type="GeneID" id="5001200"/>
    <dbReference type="Gramene" id="ABO95414">
        <property type="protein sequence ID" value="ABO95414"/>
        <property type="gene ID" value="OSTLU_9699"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9699"/>
    <dbReference type="eggNOG" id="KOG1315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_205489_0_0_1"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="50" mass="5982" checksum="0E02D88F3D5963C2" modified="2007-05-15" version="1" fragment="single">CDTVKPDLCHHCSVCKRCVLKMDHHCPWVMNCVGARNYRYFFNFIAYAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWE1</accession>
    <name>A4RWE1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
            <ecNumber evidence="2">7.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_31307</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417314.1">
        <property type="nucleotide sequence ID" value="XM_001417277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWE1"/>
    <dbReference type="SMR" id="A4RWE1"/>
    <dbReference type="GeneID" id="5001492"/>
    <dbReference type="Gramene" id="ABO95607">
        <property type="protein sequence ID" value="ABO95607"/>
        <property type="gene ID" value="OSTLU_31307"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31307"/>
    <dbReference type="eggNOG" id="ENOG502QPJC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008743_3_1_1"/>
    <dbReference type="OMA" id="MATTAMQ"/>
    <dbReference type="OrthoDB" id="5210at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001953">
        <property type="entry name" value="PRK00733.2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001960">
        <property type="entry name" value="PRK00733.3-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="699"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="729"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="800"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="822" mass="85653" checksum="65CD857E3881F5A3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWI1</accession>
    <name>A4RWI1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417335.1">
        <property type="nucleotide sequence ID" value="XM_001417298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWI1"/>
    <dbReference type="GeneID" id="5001533"/>
    <dbReference type="Gramene" id="ABO95628">
        <property type="protein sequence ID" value="ABO95628"/>
        <property type="gene ID" value="OSTLU_31344"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31344"/>
    <dbReference type="HOGENOM" id="CLU_2241126_0_0_1"/>
    <dbReference type="OrthoDB" id="10519850at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11694" checksum="505894B215A23D3A" modified="2007-05-15" version="1">MATDASNADDARGARRPSDDALARAYELLDARGRGYFTARDVRRVADANGFADWSDERVRAMVSAFKPEVERRVTRDGADESLFRMSRVEFERAVARAGARAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWP7</accession>
    <name>A4RWP7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Initiator tRNA phosphoribosyl transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWP7"/>
    <dbReference type="STRING" id="436017.A4RWP7"/>
    <dbReference type="GeneID" id="5001558"/>
    <dbReference type="Gramene" id="ABO95659">
        <property type="protein sequence ID" value="ABO95659"/>
        <property type="gene ID" value="OSTLU_15209"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15209"/>
    <dbReference type="eggNOG" id="KOG2634">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027654_0_0_1"/>
    <dbReference type="OMA" id="SHIEGWI"/>
    <dbReference type="OrthoDB" id="498231at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043399">
        <property type="term" value="F:tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019988">
        <property type="term" value="P:charged-tRNA amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007306">
        <property type="entry name" value="Rit1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033421">
        <property type="entry name" value="Rit1_DUSP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033449">
        <property type="entry name" value="Rit1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811:SF0">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04179">
        <property type="entry name" value="Init_tRNA_PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17184">
        <property type="entry name" value="Rit1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rit1 N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Rit1 DUSP-like" evidence="1">
        <location>
            <begin position="306"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="45085" checksum="2AC83335BA1788B5" modified="2007-05-15" version="1">MSATRLNRRVAMACAAGRGGMIVDATRSAVKRFPDALSKTVPIWCDALNRACARAKRDAGAADADDRAWFEGPHLPEWVAEHERNSIRALVPEFEASLKSTGWDVGELAAILEKPFRCVWVSRGEDGAELSLESLAEADFTPLILVTASAPLHWRGERRVGVNGHSFAYVPGAADDEESWSRGLTADMFHEHRDALLHASERDIDNIIARIVDGRIGKPRELDPRSRLAPRGCAPMDSRAAEEANRSNGAICAGGMRELSPECGIGRCSIASFAVYDRADMEKLADAFLHVGETVVDPSKACSTAFLHVPARKAKVSRTDLMKALPRCIDFARRTFETPGARLCVTCDDGVDHSVAVAVALCIAMGPSPCSNADLDKDDVRKQLAAVSKTHPDARPTRASLKQVYNFFLHSEVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWX8</accession>
    <name>A4RWX8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_31494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417655.1">
        <property type="nucleotide sequence ID" value="XM_001417618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWX8"/>
    <dbReference type="STRING" id="436017.A4RWX8"/>
    <dbReference type="GeneID" id="5002094"/>
    <dbReference type="Gramene" id="ABO95948">
        <property type="protein sequence ID" value="ABO95948"/>
        <property type="gene ID" value="OSTLU_31494"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31494"/>
    <dbReference type="eggNOG" id="KOG1743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124519_1_0_1"/>
    <dbReference type="OMA" id="MWLTDAQ"/>
    <dbReference type="OrthoDB" id="204784at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="137" mass="14934" checksum="A3FD28EB8FBA12BB" modified="2007-05-15" version="1">MDDRKKIGIGLTSFGCGFTALGVVFFFDRGLLAMGNLMFLSGVTLTIGPKQTVKFFVRPRNQRGAFCFLFGLALVLYGWPFIGLLVEGYGFVALFSAFFPTVLIFLKRVPVLGSFLSLPGVKHVTTSIIGKSQTLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXE6</accession>
    <name>A4RXE6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417987.1">
        <property type="nucleotide sequence ID" value="XM_001417950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXE6"/>
    <dbReference type="GeneID" id="5001920"/>
    <dbReference type="Gramene" id="ABO96280">
        <property type="protein sequence ID" value="ABO96280"/>
        <property type="gene ID" value="OSTLU_31667"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31667"/>
    <dbReference type="HOGENOM" id="CLU_2065425_0_0_1"/>
    <dbReference type="OrthoDB" id="10584583at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="119" mass="12756" checksum="15DDDFA0782E2673" modified="2007-05-15" version="1">MTTPASASASTPASTPKPKSAMEVKLSDALSAARAKAKEIEDELADSPLRSPFKQRMKAGVREHPIRRLQGAAVRLYKRTKHNVIKRVERATEKNPTAVGGGVLGFAVLVLASRRGRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXL6</accession>
    <name>A4RXL6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidinotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417775.1">
        <property type="nucleotide sequence ID" value="XM_001417738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXL6"/>
    <dbReference type="GeneID" id="5001727"/>
    <dbReference type="Gramene" id="ABO96068">
        <property type="protein sequence ID" value="ABO96068"/>
        <property type="gene ID" value="OSTLU_31738"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31738"/>
    <dbReference type="eggNOG" id="ENOG502QV2Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077407_0_0_1"/>
    <dbReference type="OMA" id="HCTRLPC"/>
    <dbReference type="OrthoDB" id="505065at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014541">
        <property type="entry name" value="Amdntrnsf_FN0238"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43224">
        <property type="entry name" value="AMIDINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43224:SF1">
        <property type="entry name" value="AMIDINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19420">
        <property type="entry name" value="DDAH_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028188">
        <property type="entry name" value="Amdntrnsf_FN0238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33405" checksum="E4080BDC61A60281" modified="2007-05-15" version="1">MIVPSAFGTNAQAARDNHFMASTSDGLSVLEIRERAVAEHKALYRGLRALGIEINLFTHDEKHATPDACFPNNWHTLRDGKLKLFPMKDENRRLERREDIIEFLKHKHPNLVVDDSLLRYERQDPPKFLEGTGSLVVDHEERVAYVALSERAHEEVVAEHCAAENLTPITFKALDARGRPIYHTNVMMSVCSSVAIVCADSIADPADRRRVLDALAAGGRREIITITHAQVDAFCGNVLELRTASGEPALACSARAFAAFDDAQRARLRAAFDDRVVAVDFSTIERVGGGGVRCAVAEHFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXN4</accession>
    <name>A4RXN4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_87306</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417787.1">
        <property type="nucleotide sequence ID" value="XM_001417750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXN4"/>
    <dbReference type="STRING" id="436017.A4RXN4"/>
    <dbReference type="GeneID" id="5001733"/>
    <dbReference type="Gramene" id="ABO96080">
        <property type="protein sequence ID" value="ABO96080"/>
        <property type="gene ID" value="OSTLU_87306"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87306"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_817211_0_0_1"/>
    <dbReference type="OrthoDB" id="439993at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08030">
        <property type="entry name" value="LA_like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12291">
        <property type="entry name" value="RRM1_La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="5">
        <location>
            <begin position="19"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="148"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="273"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="38650" checksum="17926997658D3D61" modified="2007-05-15" version="1">MVGMRFGSTEFRQKYDFVAQLTPEDGAKICRQVSFYFSDSNIGRDDYLLREVVKSKREGHDGAVELATIARFQKMRELLAPYGGYDNFSAMMPKVAEALSQSDIVEACENGTRVKRKSLTIDGKEPDFSTDEGMLQYRQAMMVELDKRYVFASPFSRHATMDSIRAFFDGVGQVKSIRLRRHTASKDFRGSVFVEFATEEEARHVAARTDLVHEGAKIELAMKSDYLEKKKAESLLQKEKRRQEAIARGQDPENIPPEPEPVYVGKVPEGFVPGRGGGRGGGRGGGRGGGRGGGRGGGRGGGRGGDRGGDFGHDGPGRGPGFGYGGPDRGAPRFGFGAPGPQRPGPPQRFGRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXQ7</accession>
    <name>A4RXQ7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418034.1">
        <property type="nucleotide sequence ID" value="XM_001417997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXQ7"/>
    <dbReference type="GeneID" id="5002113"/>
    <dbReference type="Gramene" id="ABO96327">
        <property type="protein sequence ID" value="ABO96327"/>
        <property type="gene ID" value="OSTLU_31779"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31779"/>
    <dbReference type="HOGENOM" id="CLU_1470528_0_0_1"/>
    <dbReference type="OMA" id="HEGIEAY"/>
    <dbReference type="OrthoDB" id="10491549at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="20850" checksum="98E0056AC0B657C4" modified="2007-05-15" version="1">MQSLTDASVVGLPNDELFRRAKRIKFRGVYKTPSQVTDGECHLYVLCEAQRFNAQLPLTATSDGGGEDAAGQSKSRTRMFASEDFHLLGHIDAFTNLRSLQLHANARLRRKKGMYYVIQIDGAKLTDVSDITVVEDEDEPSAAPDEKNLGRRSRGRIRRRRRLYRLHSARRTQRSARNATGRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXS4</accession>
    <name>A4RXS4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_31796</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417806.1">
        <property type="nucleotide sequence ID" value="XM_001417769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXS4"/>
    <dbReference type="STRING" id="436017.A4RXS4"/>
    <dbReference type="GeneID" id="5002119"/>
    <dbReference type="Gramene" id="ABO96099">
        <property type="protein sequence ID" value="ABO96099"/>
        <property type="gene ID" value="OSTLU_31796"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31796"/>
    <dbReference type="HOGENOM" id="CLU_093286_0_0_1"/>
    <dbReference type="OMA" id="EDIRTHG"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051257">
        <property type="entry name" value="Diverse_CBS-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080:SF29">
        <property type="entry name" value="OS02G0818000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="20"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="81"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="142"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="199" mass="21917" checksum="B40291A4495F1B56" modified="2007-05-15" version="1">MDRVQISDPDPFSAKASDYMSTPAAFVTPELELGDPIVKKLLRSYSGVPVLDKSRHVIGVLSHKDISAVEVLEKSKVKDVMSKPAHVVTSGANLAQVWAEMLQWKVWRLPVVDPVSKQLVGVLCRSDILTPILNTAEDIRTHGEEVEREEHMGMLKDEKDEEDALADDEGSAEFFSADADADVVDDADDDNGEPYSRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXW2</accession>
    <name>A4RXW2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_38634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417822.1">
        <property type="nucleotide sequence ID" value="XM_001417785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXW2"/>
    <dbReference type="GeneID" id="5001716"/>
    <dbReference type="Gramene" id="ABO96115">
        <property type="protein sequence ID" value="ABO96115"/>
        <property type="gene ID" value="OSTLU_38634"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38634"/>
    <dbReference type="eggNOG" id="ENOG502S8XU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120782_1_0_1"/>
    <dbReference type="OrthoDB" id="498381at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="75"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="146" mass="17366" checksum="6B76E1E97D9BE9CA" modified="2007-05-15" version="1" fragment="single">MDWEPLQKRRFARLEELQAFKAKEGHVQVPRTNQYEPGMKTWLYHQQRCFREGKLSKDKIQALRDVGVTLKMTQRVSWDARLMELIEFKRIHGHCNVPATWRHNKELGSWVGTQRKYKRTGKLSDERISALTSVGFEWEPKKALSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXZ2</accession>
    <name>A4RXZ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417838.1">
        <property type="nucleotide sequence ID" value="XM_001417801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXZ2"/>
    <dbReference type="STRING" id="436017.A4RXZ2"/>
    <dbReference type="GeneID" id="5001791"/>
    <dbReference type="Gramene" id="ABO96131">
        <property type="protein sequence ID" value="ABO96131"/>
        <property type="gene ID" value="OSTLU_31867"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31867"/>
    <dbReference type="HOGENOM" id="CLU_608889_0_0_1"/>
    <dbReference type="OrthoDB" id="498968at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="450" mass="49354" checksum="57FF6775A612029A" modified="2007-05-15" version="1">MNKEGTARAKTQPADLALDVASVSAKHAVITCEVKDAKVSPPEFEIKIIDLSRNGVMLNGERINKDEYYELKDGDAVTMPFHLEYRFELNPDGTLPRATRVPVDETPTPLQKKRASPATAAVENGGGAKKPRESCDDNEGQGQAMRELTTENGELRQRVEALEKELEEARRREKEAAAPTEAAEGDNDDVRAEALREAEEKVKQAEARAEKLNAELEEAQAVVEGAASATKEMETKLAELQSALDAAETKRVEAIASVQKECAEEIENLNARVARIQSVRKEELEEAEARVKAFASSARESRDLAKQLLDKLNESVQLVASDADAAHGDDDEMTHETTPQRRDGSDEKAAEDAAEDEPAKDDDDDINDNDDDDDINDKDDDSLEQLDVDNHFSDSILADVEFPPTEKPTQVAAPLHDIGNSPRTDQPSPSKRVGRDIDDRSPLPASVLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYB9</accession>
    <name>A4RYB9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_40924</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the APC3/CDC27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418358.1">
        <property type="nucleotide sequence ID" value="XM_001418321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYB9"/>
    <dbReference type="STRING" id="436017.A4RYB9"/>
    <dbReference type="GeneID" id="5002300"/>
    <dbReference type="Gramene" id="ABO96651">
        <property type="protein sequence ID" value="ABO96651"/>
        <property type="gene ID" value="OSTLU_40924"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40924"/>
    <dbReference type="eggNOG" id="KOG1126">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042054_0_0_1"/>
    <dbReference type="OMA" id="LMGKVCK"/>
    <dbReference type="OrthoDB" id="498366at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000018">
        <property type="entry name" value="Cell division cycle protein 27 homolog B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF13">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="182"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="216"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="318"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="375" mass="42458" checksum="307A2ADAB58CDCC5" modified="2007-05-15" version="1">MANLSQVPEDGEVSYESGHYSDQRDQGTWSWQPARTAEGAVLAFKELRPLAEGLRHLAMYRCEEAIHSFQQLSRSQYDTAYVLCAMAKAHSEMVDYANAAQAFEEARAAAPYRLEGLDVYSTVLWHLKEEVKLAHLAQEVQSLDRLAPETWCVLGNCFSLQKEHETALKFFQRAIQLDPKCTYAHTLSGHEYFANEDFEKSMNCYRAALRLDARHYNAWYGLGTVYYRQEKYVMSEYHFTYALNINPKSSVLYCYAGMAKHALNDNDAALSLLSQAIALDGKNPLARYEMAAVLMSEENYDAALAELNKLQEIAPKEASVFFLMGRIYKKLGLQEKAMINFSIALDLRPSNADVNSIKGAIEKLDADELSDEDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYC3</accession>
    <name>A4RYC3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418144.1">
        <property type="nucleotide sequence ID" value="XM_001418107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYC3"/>
    <dbReference type="GeneID" id="5002239"/>
    <dbReference type="Gramene" id="ABO96437">
        <property type="protein sequence ID" value="ABO96437"/>
        <property type="gene ID" value="OSTLU_31976"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31976"/>
    <dbReference type="HOGENOM" id="CLU_1216488_0_0_1"/>
    <dbReference type="OrthoDB" id="537706at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045287">
        <property type="entry name" value="PAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35115">
        <property type="entry name" value="CYCLIN DELTA-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35115:SF1">
        <property type="entry name" value="PROTEIN IN CHLOROPLAST ATPASE BIOGENESIS, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="228" mass="24166" checksum="5CB9A2FCD74D6FE2" modified="2007-05-15" version="1">MLRRALAEDERAHGVGGGAATAACGSDALDAYAPGELTNSPYATRVEAFLTRRVGRFLDADETLIERHVERGDVTSALVTAEWCADGPYAGWSRPHAVHAATLARFGRAAEARDQARVALSVGPWWTMGEDGAMMTQMQTLSGYAGRSAADVRRTLEGGDVDAGGASGGEPAPTREETALKRAMDAMDAVAWGERGETWASVRERVAESLDEAGLRALSAHVLAPLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYP3</accession>
    <name>A4RYP3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL29c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">50S ribosomal protein L29, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_9845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418428.1">
        <property type="nucleotide sequence ID" value="XM_001418391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYP3"/>
    <dbReference type="STRING" id="436017.A4RYP3"/>
    <dbReference type="GeneID" id="5002220"/>
    <dbReference type="Gramene" id="ABO96721">
        <property type="protein sequence ID" value="ABO96721"/>
        <property type="gene ID" value="OSTLU_9845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9845"/>
    <dbReference type="eggNOG" id="KOG3436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158491_0_0_1"/>
    <dbReference type="OrthoDB" id="528635at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050063">
        <property type="entry name" value="Ribosomal_protein_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10916">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35/50S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10916:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="62" mass="7435" checksum="206C914DC9D308C0" modified="2007-05-15" version="1" fragment="single">KVKDFKDLSNEALLEEVTKSKKMLFQLRMRQSTRKEFKPHHFGILKTKVAQLYTVKREREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYY5</accession>
    <name>A4RYY5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418244.1">
        <property type="nucleotide sequence ID" value="XM_001418207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYY5"/>
    <dbReference type="GeneID" id="5002341"/>
    <dbReference type="Gramene" id="ABO96537">
        <property type="protein sequence ID" value="ABO96537"/>
        <property type="gene ID" value="OSTLU_92900"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92900"/>
    <dbReference type="HOGENOM" id="CLU_1328297_0_0_1"/>
    <dbReference type="OMA" id="SGTHSWW"/>
    <dbReference type="OrthoDB" id="10493385at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="23567" checksum="6FE6ED3DDF19B9A2" modified="2007-05-15" version="1">MATRQTYVIVVNSDIPGSGLQEILGLLCNHNKHLESVGNSVDASPFIDVKTAFISKKLSGTHSWWDVDRKMDWKIHNVDVVVCTQASRREMGAKWLHHAGMRWIAEQDLGKTVDVVSRVFAKIQDIDIDSEAYLDVSGGARDDAFAVREIFRRTEHCRGHWLNADEVQDVSTPDKKKANTTTKRTKSREERESLRPSFRPSFQPSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYZ7</accession>
    <name>A4RYZ7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418482.1">
        <property type="nucleotide sequence ID" value="XM_001418445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYZ7"/>
    <dbReference type="GeneID" id="5002538"/>
    <dbReference type="Gramene" id="ABO96775">
        <property type="protein sequence ID" value="ABO96775"/>
        <property type="gene ID" value="OSTLU_32199"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32199"/>
    <dbReference type="HOGENOM" id="CLU_1491423_0_0_1"/>
    <dbReference type="OrthoDB" id="498660at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="181" mass="19049" checksum="F5B843D201985D5C" modified="2007-05-15" version="1">MTSTASRGDALETRGWGRDDGETTSREATSALVANAVAVVVALTSAHGDAARAATTPGEVIGQVAGSLRAELVREERAVVDEVLKDEQIGLDVIRESKTAGEMLDLFVEKEPPLALFLVAMLLVNGSFGLVYTLFIRETSAGPGGEFGKGVVAVRQSIVKGIFAFFNSALGRYTTKDSQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ04</accession>
    <name>A4RZ04_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418250.1">
        <property type="nucleotide sequence ID" value="XM_001418213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ04"/>
    <dbReference type="STRING" id="436017.A4RZ04"/>
    <dbReference type="GeneID" id="5002500"/>
    <dbReference type="Gramene" id="ABO96543">
        <property type="protein sequence ID" value="ABO96543"/>
        <property type="gene ID" value="OSTLU_32206"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32206"/>
    <dbReference type="eggNOG" id="KOG2134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014938_0_1_1"/>
    <dbReference type="OMA" id="KPEIGMW"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006551">
        <property type="entry name" value="Polynucleotide_phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01664">
        <property type="entry name" value="DNA-3'-Pase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="223" mass="24749" checksum="83CC293EFCD637F3" modified="2007-05-15" version="1">MDAFVTRRVVAKASTTNDDDDARKRRRVAPTNDGWRTFDDSLLARLDAACEPRAKIAAFDLDDTLQKTKSGAKAFAARADDFTTLNEHVPRVLRALHDDGYKICIFSNQGGVKGALDGKRATSVRARLALLATTLETPFQFYGATQMRENDVKKYRKGEIGMWRKMVAEHNGGVAPDLKASFFVGDAAGRAQDHSAVDKEFAENVGVRFFVPEQMFVEGEAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ16</accession>
    <name>A4RZ16_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_9485</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418253.1">
        <property type="nucleotide sequence ID" value="XM_001418216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ16"/>
    <dbReference type="STRING" id="436017.A4RZ16"/>
    <dbReference type="GeneID" id="5002552"/>
    <dbReference type="Gramene" id="ABO96546">
        <property type="protein sequence ID" value="ABO96546"/>
        <property type="gene ID" value="OSTLU_9485"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9485"/>
    <dbReference type="eggNOG" id="KOG0130">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_18_3_1"/>
    <dbReference type="OMA" id="NVKVDWC"/>
    <dbReference type="OrthoDB" id="15688at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12324">
        <property type="entry name" value="RRM_RBM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008111">
        <property type="entry name" value="RNA-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033744">
        <property type="entry name" value="RRM_RBM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45894">
        <property type="entry name" value="RNA-BINDING PROTEIN 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01738">
        <property type="entry name" value="RNABINDINGM8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="27"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11710" checksum="4FF5D18C667EB073" modified="2007-05-15" version="1" fragment="single">RGDYDVMGDDDADAGGPNDPVRSVQGWIVLVTGVHEEAQEDDVHEAFADFGEIKNLHLNLDRRTGYVKGYALVEYDTKAEAQAAIDGMDGETVLDQPVRASWAFVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ63</accession>
    <name>A4RZ63_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine-rich repeat-containing N-terminal plant-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_32267</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418274.1">
        <property type="nucleotide sequence ID" value="XM_001418237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ63"/>
    <dbReference type="STRING" id="436017.A4RZ63"/>
    <dbReference type="GeneID" id="5002211"/>
    <dbReference type="Gramene" id="ABO96567">
        <property type="protein sequence ID" value="ABO96567"/>
        <property type="gene ID" value="OSTLU_32267"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32267"/>
    <dbReference type="eggNOG" id="ENOG502S8MQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_427882_0_0_1"/>
    <dbReference type="OMA" id="QAMHESC"/>
    <dbReference type="OrthoDB" id="1934521at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053038">
        <property type="entry name" value="RLP_Defense"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48064">
        <property type="entry name" value="OS01G0750400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48064:SF6">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="640" mass="69513" checksum="C38A3195B5861C74" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZB2</accession>
    <name>A4RZB2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418544.1">
        <property type="nucleotide sequence ID" value="XM_001418507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZB2"/>
    <dbReference type="STRING" id="436017.A4RZB2"/>
    <dbReference type="GeneID" id="5002181"/>
    <dbReference type="Gramene" id="ABO96837">
        <property type="protein sequence ID" value="ABO96837"/>
        <property type="gene ID" value="OSTLU_32322"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32322"/>
    <dbReference type="eggNOG" id="ENOG502QSV6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_790829_0_0_1"/>
    <dbReference type="OMA" id="RIDHTHS"/>
    <dbReference type="OrthoDB" id="2015023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009704">
        <property type="term" value="P:de-etiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090333">
        <property type="term" value="P:regulation of stomatal closure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044690">
        <property type="entry name" value="CAS_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34209:SF1">
        <property type="entry name" value="CALCIUM SENSING RECEPTOR, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34209">
        <property type="entry name" value="RHODANESE/CELL CYCLE CONTROL PHOSPHATASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="299"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="35721" checksum="95326DB555A9DF5F" modified="2007-05-15" version="1">MYAAPRCALRATNATKSFAKAEKRSGVVARASTSDKRAVTTTTTTLTALTMMTHAGAAHAGQVSDRLAAVLDAADSAADAATAVFSQAADLVAQGVELAQEAAPVVLPVAERAVKAVTPVGEAVGAYAGRAIVPAADEALKQASSASGQALSSADSALKAQGVDIAPAAKVFEEGAQIVFDATVPIAQQVADYLADASGEELATTAGELFLAYLLAPVVFKLVADIARGYRGDLRPIEAYDMLLSENAVIVDTRGSEVTVQLPGGANKRVLVCGIEKSGAFSNAAAGKVAALKIASLRGVSRGKKVILLDQNGGSAKALAKALAKQGFSKVFTVRGGYNSWSRSGLATTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZX2</accession>
    <name>A4RZX2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase kappa</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_3450</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418642.1">
        <property type="nucleotide sequence ID" value="XM_001418605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZX2"/>
    <dbReference type="STRING" id="436017.A4RZX2"/>
    <dbReference type="GeneID" id="5002961"/>
    <dbReference type="Gramene" id="ABO96935">
        <property type="protein sequence ID" value="ABO96935"/>
        <property type="gene ID" value="OSTLU_3450"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3450"/>
    <dbReference type="eggNOG" id="KOG2094">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012348_11_4_1"/>
    <dbReference type="OMA" id="YFYWIAR"/>
    <dbReference type="OrthoDB" id="1747274at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000004">
        <property type="entry name" value="DNA polymerase IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.60:FF:000012">
        <property type="entry name" value="Putative DNA-directed polymerase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.810">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050116">
        <property type="entry name" value="DNA_polymerase-Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076:SF33">
        <property type="entry name" value="DNA POLYMERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076">
        <property type="entry name" value="DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="13">
        <location>
            <begin position="88"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="427" mass="47037" checksum="EBBC9EF7E41C219E" modified="2007-05-15" version="1" fragment="single">SYGSVFTHAKAGMENVDRERVARVVYDATVGTPHHENETRKERATSKRIAAMKAKGQGMTKTEWETFGRRADERARAMERTRSGARKWLVVDMDGFYAACEELYDPALKSVPVGVAAGPSSVLTTANYVARKYGVRAAMPGFIAKKLCPDLVFVKPDFKKYVKASNESRGVFAQYNPDYIAGSLDEAYIEVTEYCEKHDTTMEAIAEEIRSKVKEATGGLTCSVGGGCSRRLAKVCSDFNKPNGQYILGTTRDDILKFLRDLPVRKMYGIGKTLERILNEFDIKTCGDLLAKRATMLALFTPKAFDFLLGIALGIGTECHPRETPEGSGGRKGVSKSETFKATADKAYLDAKMTELATEVALECQRLNLKGRMVAVKLKRSTFDVIQRQTTLAGPTNDVKTIVNSALRLMRNENSIGANMTLRLVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZZ0</accession>
    <name>A4RZZ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Plastid ribosomal protein L27 large ribosomal subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_35728</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418653.1">
        <property type="nucleotide sequence ID" value="XM_001418616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZZ0"/>
    <dbReference type="STRING" id="436017.A4RZZ0"/>
    <dbReference type="GeneID" id="5002816"/>
    <dbReference type="Gramene" id="ABO96946">
        <property type="protein sequence ID" value="ABO96946"/>
        <property type="gene ID" value="OSTLU_35728"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35728"/>
    <dbReference type="eggNOG" id="KOG4600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095424_2_0_1"/>
    <dbReference type="OMA" id="GIVTFEW"/>
    <dbReference type="OrthoDB" id="496407at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000060">
        <property type="entry name" value="Apicoplast ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_bL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_bL27_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="12932" checksum="75A3B411FFAFA7D3" modified="2007-05-15" version="1" fragment="single">MIAAASALASRFAVATALDRIAPARVDARAPRRAVIECAHKKGTGSTKNGRDSNPQYLGVKKYGEEKVQVGSIIVRQRGNKFHAGDGVGTGKDFTLYALRDGEVKFKVGANKKKFVTIVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="106" xmlns="https://uniprot.org/uniprot">
    <accession>A4S065</accession>
    <name>A4S065_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chaperone, Hsp100 family, ClpC-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CLPC2</name>
        <name evidence="8" type="ORF">OSTLU_46264</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418921.1">
        <property type="nucleotide sequence ID" value="XM_001418884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S065"/>
    <dbReference type="STRING" id="436017.A4S065"/>
    <dbReference type="GeneID" id="5002972"/>
    <dbReference type="Gramene" id="ABO97214">
        <property type="protein sequence ID" value="ABO97214"/>
        <property type="gene ID" value="OSTLU_46264"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_46264"/>
    <dbReference type="eggNOG" id="KOG1051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_1_1"/>
    <dbReference type="OMA" id="EFMEPHT"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000011">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="186"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="466"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="7">
        <location>
            <begin position="640"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="781" mass="85256" checksum="67BD5D5F87A3D89A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S099</accession>
    <name>A4S099_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase delta subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418707.1">
        <property type="nucleotide sequence ID" value="XM_001418670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S099"/>
    <dbReference type="STRING" id="436017.A4S099"/>
    <dbReference type="GeneID" id="5002724"/>
    <dbReference type="Gramene" id="ABO97000">
        <property type="protein sequence ID" value="ABO97000"/>
        <property type="gene ID" value="OSTLU_32665"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32665"/>
    <dbReference type="eggNOG" id="ENOG502SC9I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137022_1_0_1"/>
    <dbReference type="OMA" id="TECVWER"/>
    <dbReference type="OrthoDB" id="337486at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007218">
        <property type="entry name" value="DNA_pol_delta_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04081">
        <property type="entry name" value="DNA_pol_delta_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="13222" checksum="6F1AD8C2887632E6" modified="2007-05-15" version="1">MPPRSARRPPSATTIDALFRSTKPGAARPGKTKGANVAIEDDDAETIDDDDAVERDARELKTFDLTSKFGPCCGLTRIERWDRARALGLDPPKRVLEILHRRGEASARWRECVWHGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0K2</accession>
    <name>A4S0K2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine/threonine-protein kinase ATR</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_32774</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418754.1">
        <property type="nucleotide sequence ID" value="XM_001418717.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S0K2"/>
    <dbReference type="GeneID" id="5002833"/>
    <dbReference type="Gramene" id="ABO97047">
        <property type="protein sequence ID" value="ABO97047"/>
        <property type="gene ID" value="OSTLU_32774"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32774"/>
    <dbReference type="eggNOG" id="KOG0890">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000178_2_8_1"/>
    <dbReference type="OMA" id="WFLERWK"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00892">
        <property type="entry name" value="PIKKc_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012993">
        <property type="entry name" value="UME"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08064">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00802">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="15">
        <location>
            <begin position="1722"/>
            <end position="2362"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="14">
        <location>
            <begin position="2478"/>
            <end position="2786"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="16">
        <location>
            <begin position="2791"/>
            <end position="2823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="765"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO97047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="2823" mass="308873" checksum="FCA69621851ED45B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Q0</accession>
    <name>A4S0Q0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418777.1">
        <property type="nucleotide sequence ID" value="XM_001418740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Q0"/>
    <dbReference type="GeneID" id="5003013"/>
    <dbReference type="Gramene" id="ABO97070">
        <property type="protein sequence ID" value="ABO97070"/>
        <property type="gene ID" value="OSTLU_16272"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16272"/>
    <dbReference type="eggNOG" id="KOG2733">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031002_0_2_1"/>
    <dbReference type="OMA" id="PFTYAFY"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="2">
        <location>
            <begin position="78"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="498" mass="55108" checksum="9FF72704A75F2585" modified="2007-05-15" version="1">MESDYGIVDGFDEPPHAFIKSLLSKPIIVRKLADKFFGGDKTRVEDEYEALTEEELDKFFISEFGGGTFRAGREYSFILYGASGYTGSLCLEYILKTVQNLGSRVTFALAGRNEAKLRKRWADVTSRYPTEYEPGFITCDLANPVAIREMVLQARVVVNIAGPFMLTPADMLAEACIEYDTDYVDVNGEVPFTKKLIKYHDWAKANNVLVVPNAAGAGGIPDVGCFYTVRELRKRIGKDVPVSKMHMYLYGSAGGAPSGGTLATRAAMTAAMKDVAGLMANPFALGGSIEGGSRPEDADRNLSQVEYDPDYDAWKAPFTYAFYETRLIRRANWLLRDLGRFPYGRNLNYLEHLILPTEKSARDLQSSNTSSKAEEEKLRKEGRLFKLGEGLDESARDSIWSEYWFDAVTPEGEKIRTRLTGKDGYDETAHMAIELAILCSEYREKLPFRGGVLTPGVAGGDPYIEALHSTGLNFEVLSNDAKVDFSRLANAIVASSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Q4</accession>
    <name>A4S0Q4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_32826</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419019.1">
        <property type="nucleotide sequence ID" value="XM_001418982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Q4"/>
    <dbReference type="STRING" id="436017.A4S0Q4"/>
    <dbReference type="GeneID" id="5003016"/>
    <dbReference type="Gramene" id="ABO97312">
        <property type="protein sequence ID" value="ABO97312"/>
        <property type="gene ID" value="OSTLU_32826"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32826"/>
    <dbReference type="eggNOG" id="KOG0663">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="TEPGHAM"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07845">
        <property type="entry name" value="STKc_CDK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000375">
        <property type="entry name" value="Cell division related protein kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000533">
        <property type="entry name" value="cyclin-dependent kinase 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044093">
        <property type="entry name" value="STKc_CDK10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF508">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="24"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="307"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="355" mass="40061" checksum="C7397BA51ED3736A" modified="2007-05-15" version="1">MGADDDGDARDGDARAALATLTNYEKLGRIGEGTYGVVYKGRCKTTGDVVALKKVRMDRERDGMPLTSLREVRILQRVRHENVVRLLRVIQGDALNNVFLVFEYCEHDLARLIDNVKTTLTTSEVKSLMTQTLRAVEYLHERFIFHRDLKLSNLLLNQRGELKLCDFGLARTFEPIDRGSYTPKVVTLWYRAPELLFGCDTYTSAIDMWAVGCIFAEFLKHEPLFPGSTEIEQLNMICALLGSPNSHIWPGWDALPHARKFKLPEQPYNFLEINFPKLSAAGVNLLDVLLTFDPEKRGTATEALAHPFFQESPPPKPPAEMPTYPSTHSAPERGAERRNAKRSRGALDERIGAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S147</accession>
    <name>A4S147_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419091.1">
        <property type="nucleotide sequence ID" value="XM_001419054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S147"/>
    <dbReference type="GeneID" id="5003374"/>
    <dbReference type="Gramene" id="ABO97384">
        <property type="protein sequence ID" value="ABO97384"/>
        <property type="gene ID" value="OSTLU_93111"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93111"/>
    <dbReference type="HOGENOM" id="CLU_020610_0_0_1"/>
    <dbReference type="OMA" id="MAYLFVQ"/>
    <dbReference type="OrthoDB" id="10467277at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="238"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="613"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="733"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="770" mass="85385" checksum="3418D9FF257F1A23" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Q6</accession>
    <name>A4S1Q6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Squalene monooxygenase</fullName>
            <ecNumber evidence="4 9">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_88065</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>squalene + reduced [NADPH--hemoprotein reductase] + O2 = (S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25282"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:15441"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="4 9"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419189.1">
        <property type="nucleotide sequence ID" value="XM_001419152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Q6"/>
    <dbReference type="STRING" id="436017.A4S1Q6"/>
    <dbReference type="GeneID" id="5003166"/>
    <dbReference type="Gramene" id="ABO97482">
        <property type="protein sequence ID" value="ABO97482"/>
        <property type="gene ID" value="OSTLU_88065"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88065"/>
    <dbReference type="eggNOG" id="KOG1298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026390_1_0_1"/>
    <dbReference type="OMA" id="AKRTFYW"/>
    <dbReference type="OrthoDB" id="1678617at2759"/>
    <dbReference type="UniPathway" id="UPA00767">
        <property type="reaction ID" value="UER00752"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835:SF0">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Squalene epoxidase" evidence="10">
        <location>
            <begin position="162"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="478" mass="51692" checksum="EC485782A224B572" modified="2007-05-15" version="1" fragment="single">VAGASLAHSLGGEGRRVLCVERDLSTPDRIVGELLQPGGYLKLKELGLESCVEGIDAQKVYGYTMFKNGEVATMTYPLEGRSDDVAGRSFHNGRFVQKLRQAAMKVEGVELRQGTVKKLLNREGGDWKEGETVGGVSYTVGDVWDEKKQQVIPGPSVTKTVFAPLTIVCDGHFSSLRSKLSPQASPDHPSHFVGVILKGAPSDLLPNGSHGHVVLGDPSPVLFYPISSTEVRCLVDIPASVKMPSVAKGEMAKYVLEKIVPQVPEQLQPHLIKAVENGQFRSMPNKTMAAKPQRTPGAVMLGDAFNMRHPLTGGGMTVALNDIATFKSMLSPLPDFSDAALTGAKLDEFYRHRTRPALTINTLANALYAVFCSSGDTSMEEMRQACFEYLKLGGSYARGPIALLGGLDPNPLNLVSHFFSVALFGIGRLMVPLPTPERLFKGGNILAGACKIIFPIVKGEGFTRMFFPAWLRTRLGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1S4</accession>
    <name>A4S1S4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phospholipase A2</fullName>
            <ecNumber evidence="2">3.1.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_93161</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the H-rev107 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419198.1">
        <property type="nucleotide sequence ID" value="XM_001419161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1S4"/>
    <dbReference type="STRING" id="436017.A4S1S4"/>
    <dbReference type="GeneID" id="5003196"/>
    <dbReference type="Gramene" id="ABO97491">
        <property type="protein sequence ID" value="ABO97491"/>
        <property type="gene ID" value="OSTLU_93161"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93161"/>
    <dbReference type="HOGENOM" id="CLU_675010_0_0_1"/>
    <dbReference type="OMA" id="CRLAVDQ"/>
    <dbReference type="OrthoDB" id="421951at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070292">
        <property type="term" value="P:N-acylphosphatidylethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051496">
        <property type="entry name" value="H-rev107_PLA/AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007053">
        <property type="entry name" value="LRAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13943">
        <property type="entry name" value="HRAS-LIKE SUPPRESSOR - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13943:SF77">
        <property type="entry name" value="LRAT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04970">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51934">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LRAT" evidence="7">
        <location>
            <begin position="38"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="41974" checksum="D510DDFDB68C4CD6" modified="2007-05-15" version="1" fragment="single">VSRARLHGAPRGRARGRAWPRRGRARRPGDVVFWHRVAREFFDVGFEHWAVYVGRVGVADDALGIWRWMRDGDDVDAAVECVVHLWGAPEGGEDEGGERNRDMDANAACVLSPLADVGEDPRCGNERFDATHAPLRIGEIVDRCRLAVDQGFYEGRYGAYCVRANNCEHFATWARYGVRFSQQIEDTVSLGVNIARVAASLLARRDVGTDPNAMNMAKHLIMGTRVNPNDEEEIAAAVKDMHGGESPKYTAEEDVAYVLDYIIDRVDVEVEDQLERDRERVHVPWSSRPVPASREIATLSFGRARSVRPGVPEEEESLSITAGQVSAFAGQVGRFVGQASTSAFRILGAGLEELARTSQPPPSADPPISPPATTAGERETDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Y7</accession>
    <name>A4S1Y7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_33265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419231.1">
        <property type="nucleotide sequence ID" value="XM_001419194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Y7"/>
    <dbReference type="GeneID" id="5003146"/>
    <dbReference type="Gramene" id="ABO97524">
        <property type="protein sequence ID" value="ABO97524"/>
        <property type="gene ID" value="OSTLU_33265"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33265"/>
    <dbReference type="HOGENOM" id="CLU_1621744_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="164" mass="18671" checksum="F16658339CCE9872" modified="2007-05-15" version="1">MARQKYLLEHSGAFKREIGAMAAKINKRLHELVMARGRVESVRDDSIVYERIRSEATRDVTGAETFAAAAASVARHWRDFPVGGWPWPTAPPPAPLTKGEKAVLFLKKLKCHGAREHDKFVNIMNMHKYNFLSVRDVDREVAALLPRHPLLREFRETFLRPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4S218</accession>
    <name>A4S218_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419249.1">
        <property type="nucleotide sequence ID" value="XM_001419212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S218"/>
    <dbReference type="GeneID" id="5003105"/>
    <dbReference type="Gramene" id="ABO97542">
        <property type="protein sequence ID" value="ABO97542"/>
        <property type="gene ID" value="OSTLU_33293"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33293"/>
    <dbReference type="HOGENOM" id="CLU_2965114_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="59" mass="6807" checksum="4AC3CF1E0CBDB4D7" modified="2007-05-15" version="1">MICQHPSRATVHVFAARVVSREFKPPIARERHAEYARARRREAQHGAIDVRLRSHGYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2F4</accession>
    <name>A4S2F4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">F-ATPase family transporter: protons (Vacuolar)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_7408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419524.1">
        <property type="nucleotide sequence ID" value="XM_001419487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2F4"/>
    <dbReference type="STRING" id="436017.A4S2F4"/>
    <dbReference type="GeneID" id="5003676"/>
    <dbReference type="Gramene" id="ABO97817">
        <property type="protein sequence ID" value="ABO97817"/>
        <property type="gene ID" value="OSTLU_7408"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7408"/>
    <dbReference type="eggNOG" id="KOG1664">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073641_1_0_1"/>
    <dbReference type="OMA" id="CRPQDHL"/>
    <dbReference type="OrthoDB" id="10263003at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="216" mass="23212" checksum="07F335F508D98175" modified="2007-05-15" version="1" fragment="single">MNQADVDKQINQMVQFIKQEANEKAREIAIATEEEFNIEKLSMVDGEKIKIAKEYERKETTVDTAKKIEASTGRNAMRLKVLSARAQAMETVVEEARAKLAETSADAGRYRTLMTALIVQGARKLGDASVRVRCRECDAAVAREAVAAAAAEMPGTTVTLDESSSLPAAPACSGGVEVANSTGKIVCDNTLDARLRIAYENGTPAIRAKIFGESSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2U0</accession>
    <name>A4S2U0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ClpR6</name>
        <name evidence="4" type="ORF">OSTLU_33566</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419805.1">
        <property type="nucleotide sequence ID" value="XM_001419768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2U0"/>
    <dbReference type="STRING" id="436017.A4S2U0"/>
    <dbReference type="MEROPS" id="S14.010"/>
    <dbReference type="GeneID" id="5003807"/>
    <dbReference type="Gramene" id="ABO98098">
        <property type="protein sequence ID" value="ABO98098"/>
        <property type="gene ID" value="OSTLU_33566"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33566"/>
    <dbReference type="eggNOG" id="KOG0840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_2_1"/>
    <dbReference type="OMA" id="MMARDTY"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="210" mass="22343" checksum="728172F39446F8B2" modified="2007-05-15" version="1">MRTTRTTRARRPHAPPGAITSGPETVPVMVPDGRGGGEDVFGALARDRIVFLGTRIDEQVAAETCARLLQLESEDPEGEIRVWVNCVAGTQYCVTAILDTMEYVSCPVSTVALGCVAGPPVMLVAAGDKGKRYGMSSARIVLSQPLGGLAGTSIEVKIQATELNRNAKAQVGFIAKYTGRDADELEAMMARDTYMGVDEAIDFGLIDHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S354</accession>
    <name>A4S354_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_8318</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419655.1">
        <property type="nucleotide sequence ID" value="XM_001419618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S354"/>
    <dbReference type="GeneID" id="5003525"/>
    <dbReference type="Gramene" id="ABO97948">
        <property type="protein sequence ID" value="ABO97948"/>
        <property type="gene ID" value="OSTLU_8318"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8318"/>
    <dbReference type="eggNOG" id="KOG0606">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_26_1"/>
    <dbReference type="OMA" id="LPHYFDY"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="7">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14423" checksum="845DC97794893A0D" modified="2007-05-15" version="1" fragment="single">GTPDYLAPEILLCEPCGEGVDWWALGVMAYEMLVGVPPFNASTPLAIFARIINGKVEWPGSGAALSDESKDFVNALLVHDVEARLGSNDDANDIKAHPWFADVTWEHVYDKSAASVFVPKPESRQDTSYFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S371</accession>
    <name>A4S371_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gem-associated protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_33696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419662.1">
        <property type="nucleotide sequence ID" value="XM_001419625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S371"/>
    <dbReference type="STRING" id="436017.A4S371"/>
    <dbReference type="GeneID" id="5003873"/>
    <dbReference type="Gramene" id="ABO97955">
        <property type="protein sequence ID" value="ABO97955"/>
        <property type="gene ID" value="OSTLU_33696"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33696"/>
    <dbReference type="eggNOG" id="ENOG502QPK4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027828_0_0_1"/>
    <dbReference type="OMA" id="ASKHWED"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017364">
        <property type="entry name" value="GEMIN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035426">
        <property type="entry name" value="Gemin2/Brr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794">
        <property type="entry name" value="GEMIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794:SF2">
        <property type="entry name" value="PROTEIN SINE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04938">
        <property type="entry name" value="SIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038038">
        <property type="entry name" value="SMN_Gemin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="27962" checksum="36F20A7E660451A2" modified="2007-05-15" version="1">MASESSESEDDGLRRRALAVDGEPDYSTGPPMDGFEYLRRVAFEARQTPDIMRAENMDLTALEEETATSGGVTADEETEFAPPAWAKPDRAWVRRTVGDFSDLRVRLSRILARFPTSVRRGSYPSNADKRDWERFCVDVREPPLGALVAMDAVTCAYLLRHISRGLFRYDYDSDGVDVDDVIRRLRWFHALVARVDLPLDADTEASIRSAMKGVARGRLSTSSEDDELLPHLNLAIAIGGGYFKQWRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S393</accession>
    <name>A4S393_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nucleolar protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_16944</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.</text>
    </comment>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
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        <text evidence="2">Belongs to the NOP14 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO98349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420019.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S393"/>
    <dbReference type="GeneID" id="5004244"/>
    <dbReference type="Gramene" id="ABO98349">
        <property type="protein sequence ID" value="ABO98349"/>
        <property type="gene ID" value="OSTLU_16944"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG2147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008874_2_0_1"/>
    <dbReference type="OMA" id="KSCWPSL"/>
    <dbReference type="OrthoDB" id="497561at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007276">
        <property type="entry name" value="Nop14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183">
        <property type="entry name" value="NOP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04147">
        <property type="entry name" value="Nop14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="258"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="951"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="274"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="374"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="450"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="962"/>
            <end position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007466"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024695"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="975" mass="108233" checksum="A712E7ADEA950156" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3D2</accession>
    <name>A4S3D2_OSTLU</name>
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        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_16977</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="436017.A4S3D2"/>
    <dbReference type="GeneID" id="5004214"/>
    <dbReference type="Gramene" id="ABO98366">
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        <property type="gene ID" value="OSTLU_16977"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16977"/>
    <dbReference type="eggNOG" id="KOG2216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546786_0_0_1"/>
    <dbReference type="OMA" id="SKYPNID"/>
    <dbReference type="OrthoDB" id="20582at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019163">
        <property type="entry name" value="THO_Thoc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375">
        <property type="entry name" value="FMS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375:SF3">
        <property type="entry name" value="THO COMPLEX SUBUNIT 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09766">
        <property type="entry name" value="FmiP_Thoc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
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        <location>
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            <end position="319"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="469" mass="51642" checksum="397B49806CC90A8B" modified="2007-05-15" version="1">MPPRKRAASAPSEPTSPVAAHRTTTSLDVPSRVGAPSPAPNAEDATPESTEAQFELIQELTQELRENVAQLVEEGTKTSDARKPTVETCMKTLASVRTAQRRALMGLEYLKAGTRRRDKETDPARVRAATVAYETAWRESALKRHADAEGSGGGVSAGGIELMELKEYEADAKRRGLPTKKPRDEYELMTRRLAHELIVRREMVEEQNALKAELAALQQQVAEKKKLLGGSLEATMTNVRKSAEPLRRMFDLAYASTEDLDARIGLLPVPLHVLYAQLKHLQQNEEEIKVELVGRIDDAQNFKQKKASEEEGELVDEGAENNRRSKKRKARGGRQAASASSSLYEEHPLRVEVGFGATKVFFTYLTKLHVVVVSSKPEDEKFLGELFPDDDGSEMPNHAVAVVAPNFTFDASCAPSNAKPYKWAQNLAGLSFLPPFPAPIPDTIDAGKVSAKANAEEVVRAIREKLDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3R7</accession>
    <name>A4S3R7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_26149</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420141.1">
        <property type="nucleotide sequence ID" value="XM_001420104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3R7"/>
    <dbReference type="TCDB" id="1.A.17.3.10">
        <property type="family name" value="the calcium-dependent chloride channel (ca-clc) family"/>
    </dbReference>
    <dbReference type="GeneID" id="5004150"/>
    <dbReference type="Gramene" id="ABO98434">
        <property type="protein sequence ID" value="ABO98434"/>
        <property type="gene ID" value="OSTLU_26149"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26149"/>
    <dbReference type="eggNOG" id="ENOG502QZ1Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005705_0_0_1"/>
    <dbReference type="OMA" id="WIRISNS"/>
    <dbReference type="OrthoDB" id="497950at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
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</entry>
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</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="11020" checksum="91FC9A2FCCC9A5AF" modified="2007-05-15" version="1" fragment="single">LSQAVPFVGFGLCDNAVMIMAGESIETALGVGLGLSTMAAAGFGNTVSDVVGIGLSSKIETFAERLGFQAPQNLTQAQRMTAAVRWAKVAGATGGVTVGCLLGMFPLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S444</accession>
    <name>A4S444_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26278</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420030.1">
        <property type="nucleotide sequence ID" value="XM_001419993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S444"/>
    <dbReference type="STRING" id="436017.A4S444"/>
    <dbReference type="GeneID" id="5003930"/>
    <dbReference type="Gramene" id="ABO98323">
        <property type="protein sequence ID" value="ABO98323"/>
        <property type="gene ID" value="OSTLU_26278"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26278"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2268304_0_0_1"/>
    <dbReference type="OMA" id="WLARRDC"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="45"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="103" mass="11391" checksum="F1B13AEF592C0138" modified="2007-05-15" version="1">MLELESTYEALEAGAGAETRGASANVLARLPRREYRGTTMTTRVCAVCLETFVDGEVVKRASSTCSHEFHDACIDAWLARRDCCPMCRTRAEAPTGRVEFEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S473</accession>
    <name>A4S473_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleoporin Nup159/Nup146 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_3024</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420221.1">
        <property type="nucleotide sequence ID" value="XM_001420184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S473"/>
    <dbReference type="STRING" id="436017.A4S473"/>
    <dbReference type="GeneID" id="5004192"/>
    <dbReference type="Gramene" id="ABO98514">
        <property type="protein sequence ID" value="ABO98514"/>
        <property type="gene ID" value="OSTLU_3024"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3024"/>
    <dbReference type="eggNOG" id="KOG1033">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006994_0_0_1"/>
    <dbReference type="OMA" id="ASYKFNC"/>
    <dbReference type="OrthoDB" id="498170at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009640">
        <property type="term" value="P:photomorphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039462">
        <property type="entry name" value="Nup159/Nup146_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044630">
        <property type="entry name" value="SPA1/2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44218">
        <property type="entry name" value="PROTEIN SPA1-RELATED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44218:SF6">
        <property type="entry name" value="PROTEIN SUPPRESSOR OF PHYA-105 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16755">
        <property type="entry name" value="Beta-prop_NUP159_NUP214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nucleoporin Nup159/Nup146 N-terminal" evidence="7">
        <location>
            <begin position="81"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="175"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="33980" checksum="F4477BA53ECB3D61" modified="2007-05-15" version="1" fragment="single">NSMVCCASWDRDGELFATAGTSKSICVYETSAVMTLGARVHCPAVEFEAHSKVSALCYNPYVKQSIASGDYQGVVQLWDVQKETSTWENTTHRRRVWSIDFSHIDPTKLASASDDGTVRIFSTTTKEGVCTLQNRANVCSVKFHPTSAHMLAIGSADHRIHVYDLRQPSTPLMTLQGHRKAVSYVHWVGDELVSASTDNTLKLWDIKRNDPRTACVRTYVGHTNEKNFVGLSTNADGYIACGSEDNIVHVYAKHASSPVAHYGFADKPTPMSHNRRDKGGFISSVVWSPNSKHLLAANSRGHLKILSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4F8</accession>
    <name>A4S4F8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420258.1">
        <property type="nucleotide sequence ID" value="XM_001420221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4F8"/>
    <dbReference type="GeneID" id="5004460"/>
    <dbReference type="Gramene" id="ABO98551">
        <property type="protein sequence ID" value="ABO98551"/>
        <property type="gene ID" value="OSTLU_93419"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93419"/>
    <dbReference type="HOGENOM" id="CLU_984806_0_0_1"/>
    <dbReference type="OrthoDB" id="10669403at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="283" mass="30960" checksum="87786BE1030A9C55" modified="2007-05-15" version="1">MLRCARAPTPPTPTPTPTPTRGARARVRRASTRARALDDDDARRDSRFASEDERRRAVERLAPPKRDGDRAKPRLRELGKKRAMGFTSGAASSGEAREAARRARLERRDARATRESREIMSAMRDALDAWESEIDGMTDFARASVLEQASTATEMFERLRDEGFGAVESAFAVMSWMDDAIEDAAARADEDAATSTSTSKERVEDASKASKSKTAPDGVVGALSDALRQWFAIDITELEDGRKSIVVNASAEFLAVFILLLVASAHFGGELVSDFLAPDPLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4H5</accession>
    <name>A4S4H5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26412</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420265.1">
        <property type="nucleotide sequence ID" value="XM_001420228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4H5"/>
    <dbReference type="STRING" id="436017.A4S4H5"/>
    <dbReference type="GeneID" id="5004470"/>
    <dbReference type="Gramene" id="ABO98558">
        <property type="protein sequence ID" value="ABO98558"/>
        <property type="gene ID" value="OSTLU_26412"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26412"/>
    <dbReference type="eggNOG" id="KOG1119">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069054_1_4_1"/>
    <dbReference type="OMA" id="VENMMGG"/>
    <dbReference type="OrthoDB" id="1938621at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120510">
        <property type="term" value="C:mitochondrial [4Fe-4S] assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000006">
        <property type="entry name" value="Iron-sulfur cluster assembly 2 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011:SF1">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="6">
        <location>
            <begin position="12"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="127" mass="13177" checksum="202F65EB85508334" modified="2007-05-15" version="1">MCGARASVDDGLTLTDACATRLRAIADEDGSAPARLRLAVEGGGCSGFKYEFTLERDAATARDKTFRAANGAEVVVDAISYEFVKGATIDYAEEMIKSSFEVVKNPQAETSCGCGASFGAKDGAFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4L1</accession>
    <name>A4S4L1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420455.1">
        <property type="nucleotide sequence ID" value="XM_001420418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4L1"/>
    <dbReference type="GeneID" id="5004354"/>
    <dbReference type="Gramene" id="ABO98748">
        <property type="protein sequence ID" value="ABO98748"/>
        <property type="gene ID" value="OSTLU_26449"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26449"/>
    <dbReference type="HOGENOM" id="CLU_052905_0_0_1"/>
    <dbReference type="OrthoDB" id="498243at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="50408" checksum="AC2373073CABAF85" modified="2007-05-15" version="1">MTLNERERLISAFSPPRALADDAIVVDVDAIGVNTRRDDDVRSRFAPSPSPSRSRVAAGAAAIALLGAASVAIAIAGRSGDASDAAATRARLGYTDAEKARALDVRRSIGDKRSGHGFPIFLHIPKTGGTTIETSLGVSGIAEGYCIKREDRAYELHPRYRGWENWHSIPKDYVRKSWAIVRNPYERAESEFLYWTGTYDRKLFDSLKVGYDEGNCEKFAAHLTLNVHDSKIRACYEAGGWELRAQKKCEDEINGGVASLSHWAPQMLMASRAENLFRIEECFGAEEGECPLTPWSKRHGGASVKEENIISFIHHRYHKKIEMVVTNAWHKDVPKPDLHSCWSRFDPELLNLFNTFYGGDFEHLGYDIMRSAANLGAPSQTVPKELIGLTLGQLAERLPKGERVAVNNAPTCPPKESVLEEFLHGGDKSHAQVGEATTQTTTRRASRRNTKPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4U1</accession>
    <name>A4S4U1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_44108</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Responsible for microtubule translocation. May be important for the organization of phragmoplast-specific arrays of microtubules. Plays an essential role in stabilizing the mitotic spindle. Required during mitotic cytokinesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420495.1">
        <property type="nucleotide sequence ID" value="XM_001420458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4U1"/>
    <dbReference type="STRING" id="436017.A4S4U1"/>
    <dbReference type="GeneID" id="5004570"/>
    <dbReference type="Gramene" id="ABO98788">
        <property type="protein sequence ID" value="ABO98788"/>
        <property type="gene ID" value="OSTLU_44108"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44108"/>
    <dbReference type="eggNOG" id="KOG4280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_2_0_1"/>
    <dbReference type="OMA" id="FYEDAQQ"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000019">
        <property type="entry name" value="Kinesin-like protein KIN-5D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF36">
        <property type="entry name" value="KINESIN HEAVY CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 11 12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="13">
        <location>
            <begin position="1"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="104"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO98788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="416" mass="45634" checksum="EA9E660AC71ECDC6" modified="2007-05-15" version="1" fragment="single">MIRVRPALRRETREGRGAYQRAVAATRGGKACAASAGGERALAGNGEGGTFADDGAHERQRTYEFGFDAVYDERATQEEVYARSAKPATLNALRGYNATVLAYGQTGTGKTYTMEGDRGTMLAYGQQRFGLPGNAPVTDGRERGIIPRAIEDIFDYIAKDSHARSKYLVRVSYLQIYNETVSDLLKPERTNLNIREDKKRGVFVEGQSEWVVRTPSEIYGLLERGAQLRATGSTKMNELSSRSHAVFTIIIEHSTTEDDEPVDGVDVGEGAPAQRQSITVGKLNLVDLAGSERVSLTGATGKRLDESKKINQSLSALGNVISALTDSKGRSHIPYRDSKLTRILEDSLGGNCITTVIAMVSPALEAFAESLSTLKFASRAKEIKNTATLNEDLDQKSLLRKYERELRQLRTELDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4W2</accession>
    <name>A4S4W2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420505.1">
        <property type="nucleotide sequence ID" value="XM_001420468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4W2"/>
    <dbReference type="GeneID" id="5004516"/>
    <dbReference type="Gramene" id="ABO98798">
        <property type="protein sequence ID" value="ABO98798"/>
        <property type="gene ID" value="OSTLU_17383"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17383"/>
    <dbReference type="HOGENOM" id="CLU_1039725_0_0_1"/>
    <dbReference type="OMA" id="TWATETY"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35465">
        <property type="entry name" value="CAVEOLIN-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35465:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673065" evidence="2">
        <location>
            <begin position="40"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="268" mass="28747" checksum="AFB0D8D129233119" modified="2007-05-15" version="1">MSTPPTPTARRRARRRARATRLLALLAAVVARAVTRAEARATARRPTTLTPGTRARDVELAFGRAHAYDVRDLKANTAYEVKVSYRATSAAAIAVELDSGWLGGGGWFGGGGGWVGGTTSDGRTELRRRLLNVEKLVLSRRTLGEGMTRARVVVRAEREGVYWAGATAPEYVTYDVEVQPLFAAGKFGEIPRQSLGMICVCVAFVALAIAGARFVGDDVVWRACDALDARKRQYAAAHASAADGLDDAMNVSLRETVPVPVTTITSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4X9</accession>
    <name>A4S4X9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17396</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420347.1">
        <property type="nucleotide sequence ID" value="XM_001420310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4X9"/>
    <dbReference type="STRING" id="436017.A4S4X9"/>
    <dbReference type="GeneID" id="5004399"/>
    <dbReference type="Gramene" id="ABO98640">
        <property type="protein sequence ID" value="ABO98640"/>
        <property type="gene ID" value="OSTLU_17396"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17396"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4648">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_17_1_1"/>
    <dbReference type="OMA" id="WGLRTTH"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006169">
        <property type="entry name" value="PRK08310.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="449"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="517"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="576" mass="62580" checksum="8B49497882047313" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S518</accession>
    <name>A4S518_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAAX prenyl protease 2/Lysostaphin resistance protein A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26607</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420366.1">
        <property type="nucleotide sequence ID" value="XM_001420329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S518"/>
    <dbReference type="GeneID" id="5004478"/>
    <dbReference type="Gramene" id="ABO98659">
        <property type="protein sequence ID" value="ABO98659"/>
        <property type="gene ID" value="OSTLU_26607"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26607"/>
    <dbReference type="HOGENOM" id="CLU_809835_0_0_1"/>
    <dbReference type="OMA" id="GRDASKW"/>
    <dbReference type="OrthoDB" id="548974at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080120">
        <property type="term" value="P:CAAX-box protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592:SF15">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="3">
        <location>
            <begin position="248"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="343" mass="35641" checksum="E8DD5E69236A33EA" modified="2007-05-15" version="1">MANLDSALGTRARDGDGAATREARSTRDEASDDATRGRADPLAAYDADRDWLGAGPRWDVPHGGARFAATMLAVDASFYAAGCLAPMVEHAARASREGRDAPESAEALAEDLRRAFDDPSAFADILLDAEIIQIALGAGILALSVKKFAPLPLGWFNDAFSSSDAAVNATGRDASKWKRDAAAKAQNERASASASEAGRAILGTFLGVALVTWVLYAAGLRGGDGNGSSSVDVIEKAFAAGPHGIANLVVTTVILAPIFEETVFRGYMLPSLTKFMDTTPAIGVSALIFALIHQHGVGDTVQLVAVGLATGIVYARTRNLAASIAVHAAFNASVIALFALWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5P4</accession>
    <name>A4S5P4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420646.1">
        <property type="nucleotide sequence ID" value="XM_001420609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5P4"/>
    <dbReference type="GeneID" id="5004764"/>
    <dbReference type="KEGG" id="olu:OSTLU_17597"/>
    <dbReference type="eggNOG" id="ENOG502SSRA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_743128_0_0_1"/>
    <dbReference type="OrthoDB" id="513406at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="374" mass="40696" checksum="F12C3484D6BFC351" modified="2007-05-15" version="1" fragment="single">MQTTAIPSRTAARARGWTRAREGARNATIVRANPPGSARREGVARRGDDAATTRAIAVDERKSSSSTDAVRECAVGDALRVRLPGETRASYLEVEATSANRARGAFRGVDAVLEVCEETNRVLLSEIVDGNFGKDGKRKSTRLLRERFTRSYDGLTTTLETLRRSGEYPAPGFSGAIECEEVSRLCSLEELRARVSEDASFWADGSPKDFQGLSADEHATLNAGEILAFQCGCRPMCMVQLWTGWEDDLGRRQSIDMPFVARLLKEITEDDEIGVITVAPPGASEKLGITALLYPRKSPYKERAKLLASFGAQAAIVAGSAYYQTLIGRCLGYKEENINAHVQQYNKGVGVSKQISDLVEEELAGLSAVPASKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5T7</accession>
    <name>A4S5T7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_88811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420667.1">
        <property type="nucleotide sequence ID" value="XM_001420630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5T7"/>
    <dbReference type="STRING" id="436017.A4S5T7"/>
    <dbReference type="GeneID" id="5004785"/>
    <dbReference type="Gramene" id="ABO98960">
        <property type="protein sequence ID" value="ABO98960"/>
        <property type="gene ID" value="OSTLU_88811"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88811"/>
    <dbReference type="eggNOG" id="ENOG502SA2A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1449923_0_0_1"/>
    <dbReference type="OrthoDB" id="2018625at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36809">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36809:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="187" mass="20090" checksum="8A85505F0F83A101" modified="2007-05-15" version="1">MRARSLPSARATRVASRATTSRAPPSLSLSRAPRARSGRFRRHPPSRPPRALPDADVAPVEAWQLWFGFIAGVSPFAIAAYEFGKRVLIQRRCALCAGSGLVEVERSRGARLVKCTACGGFLPWQSWERFLSSEAGNGGVVRAPKGQTSAFYSVEKATAASREMAARRARDGEASSDRDGDDDAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5V4</accession>
    <name>A4S5V4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_51081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420835.1">
        <property type="nucleotide sequence ID" value="XM_001420798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5V4"/>
    <dbReference type="STRING" id="436017.A4S5V4"/>
    <dbReference type="CAZy" id="GT20">
        <property type="family name" value="Glycosyltransferase Family 20"/>
    </dbReference>
    <dbReference type="GeneID" id="5004874"/>
    <dbReference type="Gramene" id="ABO99128">
        <property type="protein sequence ID" value="ABO99128"/>
        <property type="gene ID" value="OSTLU_51081"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51081"/>
    <dbReference type="eggNOG" id="KOG1050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002351_3_1_1"/>
    <dbReference type="OMA" id="VHPMPIE"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000010">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000052">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1020:FF:000002">
        <property type="entry name" value="Trehalose-6-phosphate synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000079">
        <property type="entry name" value="Trehalose-6-phosphate synthase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF94">
        <property type="entry name" value="ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING] 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="839" mass="94050" checksum="12F985FFE03B128D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Z9</accession>
    <name>A4S5Z9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 2 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_88846</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eIF2 complex that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex (43S PIC). Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Eukaryotic translation initiation factor 2 eIF2 is a heterotrimeric complex composed of an alpha, a beta and a gamma subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420699.1">
        <property type="nucleotide sequence ID" value="XM_001420662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Z9"/>
    <dbReference type="STRING" id="436017.A4S5Z9"/>
    <dbReference type="GeneID" id="5004718"/>
    <dbReference type="KEGG" id="olu:OSTLU_88846"/>
    <dbReference type="eggNOG" id="KOG2768">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026663_0_1_1"/>
    <dbReference type="OMA" id="CMREGNK"/>
    <dbReference type="OrthoDB" id="10255414at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor IF2/IF5" evidence="8">
        <location>
            <begin position="76"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00054872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00063900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="213" mass="23653" checksum="18ACC32F2D04434B" modified="2007-05-15" version="1" fragment="single">LDAEFGTKKKKKSSKKKTVELEDGEEADVYAGEGRDGTNTGSGTSWDGTTRDYHYDEMLGRVFGILREKNPQLSEKSKTIIKPPQVLREGTKKTVFANLMEICNAMHRPSEHVTQYLLAELGTSGTLDGQQRLVLKGRFLPKVFEGVLRHYFIDYVICNMCKSSDTQLVKEQSSRLSYCRCQACGASRSVGSIASGFRAVGKGERRKARNATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6A2</accession>
    <name>A4S6A2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420908.1">
        <property type="nucleotide sequence ID" value="XM_001420871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6A2"/>
    <dbReference type="GeneID" id="5005016"/>
    <dbReference type="Gramene" id="ABO99201">
        <property type="protein sequence ID" value="ABO99201"/>
        <property type="gene ID" value="OSTLU_27044"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27044"/>
    <dbReference type="HOGENOM" id="CLU_365379_0_0_1"/>
    <dbReference type="OMA" id="QECCATE"/>
    <dbReference type="OrthoDB" id="10456885at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="358"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="479"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="611"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="743" mass="83994" checksum="FF522A6F73FD4A6C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6M5</accession>
    <name>A4S6M5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_27173</name>
        <name evidence="9" type="ORF">OSTLU_29736</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420973.1">
        <property type="nucleotide sequence ID" value="XM_001420936.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422921.1">
        <property type="nucleotide sequence ID" value="XM_001422884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6M5"/>
    <dbReference type="STRING" id="436017.A4S6M5"/>
    <dbReference type="GeneID" id="5004972"/>
    <dbReference type="GeneID" id="5006897"/>
    <dbReference type="Gramene" id="ABO99266">
        <property type="protein sequence ID" value="ABO99266"/>
        <property type="gene ID" value="OSTLU_27173"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01280">
        <property type="protein sequence ID" value="ABP01280"/>
        <property type="gene ID" value="OSTLU_29736"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27173"/>
    <dbReference type="KEGG" id="olu:OSTLU_29736"/>
    <dbReference type="eggNOG" id="KOG0045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043726_0_0_1"/>
    <dbReference type="OMA" id="RSPWAWH"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="99"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="474" mass="53096" checksum="B7B9172BC7446BB7" modified="2007-05-15" version="1">MAPARSNARDVESQESCAATHCAGNGHPAVAALVAPFVLAWNAIDAYLTPCLGAYARLGARGAMGSLCCCLLECFRYEDKVWAGDAALGVDCEFRGCDWARVDDLSAGSEDKPMVLYQGIIEPRDCVQGQLGDCWLVSALACLAEHPGAIKRLILNGEKSLRGKYRVRFYDGKEKRWVTVTVDDLIPCYKGTKNPIFMQPHNNEFWPLIVEKAMAKFMGSYAALDGGFGTWATHALTGDNVFLLKKRMDVERTWRRHNMKFIGKPGDGGKKDRIYHEEVEENIVRDKLFNILTQYDSIKSLIAVSRMTKNGESKDETTGLVSGHLFSVISVRWAGRSWGVGGKRFIKLRNPWSTFEWKGAWADGSKEWDKHPAIAKELAYVNDHHDGVFWMEFDDFCEYFNQIAVCDRTTKRDFSLRYDHDNKYCGPLMGCVSGCACFWCGCQGPYKLYCGHQSTTETRQATKCCGTMKVANDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6P4</accession>
    <name>A4S6P4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dihydroorotase</fullName>
            <ecNumber evidence="3">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PYR3</name>
        <name evidence="9" type="ORF">OSTLU_27192</name>
        <name evidence="10" type="ORF">OSTLU_29717</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421124.1">
        <property type="nucleotide sequence ID" value="XM_001421087.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422830.1">
        <property type="nucleotide sequence ID" value="XM_001422793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6P4"/>
    <dbReference type="STRING" id="436017.A4S6P4"/>
    <dbReference type="GeneID" id="5005191"/>
    <dbReference type="GeneID" id="5006888"/>
    <dbReference type="Gramene" id="ABO99417">
        <property type="protein sequence ID" value="ABO99417"/>
        <property type="gene ID" value="OSTLU_27192"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01189">
        <property type="protein sequence ID" value="ABP01189"/>
        <property type="gene ID" value="OSTLU_29717"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27192"/>
    <dbReference type="KEGG" id="olu:OSTLU_29717"/>
    <dbReference type="eggNOG" id="KOG2902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041558_1_0_1"/>
    <dbReference type="OMA" id="TLHHISM"/>
    <dbReference type="OrthoDB" id="1670005at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01294">
        <property type="entry name" value="DHOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="8">
        <location>
            <begin position="50"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP01189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="41609" checksum="6AD43A44724183B5" modified="2007-05-15" version="1">MPRLLSPRALASSRLSLEATVLPGRRARASPRARVAVARASSLTIARPDDWHLHVRDASKLADVVPFTSKTFKRALVMPNLTPPVRTASEAEKYRELIAKAAPASDGFEPHMTLYLTDNTTVEQVEEAHACGFVRGYKLYPAGATTNSEFGVTDVANVAKATKRMAELGLTLQVHGEVTHASVDVFDREARFIQDVLMPLLDRSPDLRVVMEHITTRDAAEFVAAAGPNVAASVTPQHVLFNRNALFKGGLRPHFYCLPILKREEHREAVLAAATSGSGKFFLGTDSAPHPKGAKEAACGCAGIFSAHAALPLYAMAFESVDALDKLEAFASHNGADFYRVPRNTETVTLEKKAWKVPDEYKFGDTTVVPFYAGEEIPWSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6X6</accession>
    <name>A4S6X6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421018.1">
        <property type="nucleotide sequence ID" value="XM_001420981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6X6"/>
    <dbReference type="GeneID" id="5004943"/>
    <dbReference type="Gramene" id="ABO99311">
        <property type="protein sequence ID" value="ABO99311"/>
        <property type="gene ID" value="OSTLU_17947"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17947"/>
    <dbReference type="HOGENOM" id="CLU_864332_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="322" mass="35434" checksum="4E0E57D876770070" modified="2007-05-15" version="1">MSPPLVPFVVCGTKKGSVPFARVKTKYGKTHTRIDNCSGDVSLLLSTLTRALGCGGSVCDDKKSVVIAFDESFDRIVKVLKSFDPRCVRGVRGAETSVPVSRASASAPTREPRTKPRHGATGSGKGVSGAAGRAEPIVITKRGAHESAKQSIDGYRLLLSRWPYWDGDVSRMYDMYHRHRRLNDDVVMSFDADSILQSSATDTNAMSDFDRAAQCASTEDALRTLGMLAMPSEFRQSRLERQREAAKRKESVARVSSGPKTSSAVVDIDPFAEYLQHDRGFAPARVSSKPAGAPRLRRWFQAHGERKVYIWRRGSNADARRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S764</accession>
    <name>A4S764_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Abscisic acid G-protein coupled receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_89082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421218.1">
        <property type="nucleotide sequence ID" value="XM_001421181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S764"/>
    <dbReference type="STRING" id="436017.A4S764"/>
    <dbReference type="GeneID" id="5005404"/>
    <dbReference type="Gramene" id="ABO99511">
        <property type="protein sequence ID" value="ABO99511"/>
        <property type="gene ID" value="OSTLU_89082"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89082"/>
    <dbReference type="eggNOG" id="KOG2417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069917_0_0_1"/>
    <dbReference type="OMA" id="IEIGVHW"/>
    <dbReference type="OrthoDB" id="264392at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="7">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="6">
        <location>
            <begin position="146"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36919" checksum="199A5192F5C871DA" modified="2007-05-15" version="1">MVRVVSRTAVLGICLLGVLSGFGMVHFPYTTVRIFHRAIPDAEVSGLERRLVQSVETIVERKKRIEILKYEIAREARMERDRNSKNGGGGSLFNRLAGGFRLPGLGEARGEQILAISAEIEALEMVNNTLFFDLHDVNLQRQRAKMSKTPYGRFLELCGVGMAVVCGYRLVAGFKRLIFKQTPTSDPISFALHIFLANKAIHIDPATLAQYLSLLLIAFLVINSMQNFITQLVKLFFAYGGGVTTDALVLFTTEMVGLYFLSSVLLVREQLPERYRHVVTEALGADLEFRFYAKFYELIFMASAALTAIALYAKHVTATVTADVSKPVRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S772</accession>
    <name>A4S772_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_43121</name>
        <name evidence="3" type="ORF">OSTLU_43341</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421221.1">
        <property type="nucleotide sequence ID" value="XM_001421184.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421256.1">
        <property type="nucleotide sequence ID" value="XM_001421219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S772"/>
    <dbReference type="STRING" id="436017.A4S772"/>
    <dbReference type="GeneID" id="5005369"/>
    <dbReference type="GeneID" id="5005409"/>
    <dbReference type="Gramene" id="ABO99514">
        <property type="protein sequence ID" value="ABO99514"/>
        <property type="gene ID" value="OSTLU_43121"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99549">
        <property type="protein sequence ID" value="ABO99549"/>
        <property type="gene ID" value="OSTLU_43341"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43121"/>
    <dbReference type="KEGG" id="olu:OSTLU_43341"/>
    <dbReference type="eggNOG" id="ENOG502QUUA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050934_0_1_1"/>
    <dbReference type="OMA" id="YKTTDEP"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000321">
        <property type="entry name" value="Chloroplast stem-loop binding protein of 41 kDa a, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF6">
        <property type="entry name" value="CHLOROPLAST STEM-LOOP BINDING PROTEIN OF 41 KDA A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="97"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="333" mass="35445" checksum="C3FA85F4842CDDCA" modified="2007-05-15" version="1" fragment="single">VAARASGEKKSVLIVNTNGGGHANIGFWLAKTLAGAGHDVTMNVVGAEDDKKMAKTPFSLFDEIRGMGVKTVWANPDEVASKHAGAKFDVVVDNNGKDMDTVGPVADFAVAAGASQFLFVSSAGIYKPTPCPPHVEGDAVKETSGHAVVEAHLKTLPLKMSSFRPQYLTGYGSNKDCEEWFFDRAVRGRPILVPGSGDQLSSVTHAEDLATMIAAAVGNDAAAGEIFNCVTTKAVTLNGMAELCAKAAGVEPNVINYDPKDVPDVEVKKAFPFRPIHFYSSSAKAQAVLGWSPKHPDLAAELKERFAYYKSIGRDKKEMSFETDDKILAAIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7B0</accession>
    <name>A4S7B0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27416</name>
        <name evidence="4" type="ORF">OSTLU_27489</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421424.1">
        <property type="nucleotide sequence ID" value="XM_001421387.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421455.1">
        <property type="nucleotide sequence ID" value="XM_001421418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7B0"/>
    <dbReference type="STRING" id="436017.A4S7B0"/>
    <dbReference type="GeneID" id="5005323"/>
    <dbReference type="GeneID" id="5005357"/>
    <dbReference type="Gramene" id="ABO99717">
        <property type="protein sequence ID" value="ABO99717"/>
        <property type="gene ID" value="OSTLU_27416"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99748">
        <property type="protein sequence ID" value="ABO99748"/>
        <property type="gene ID" value="OSTLU_27489"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27416"/>
    <dbReference type="KEGG" id="olu:OSTLU_27489"/>
    <dbReference type="eggNOG" id="KOG1695">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1079240_0_0_1"/>
    <dbReference type="OMA" id="YWHTIRN"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF260">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="95"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="29607" checksum="453912EC905ABC85" modified="2007-05-15" version="1">MYRHCDGDGAKAAKYWLQYMPMRNRAEVIRMMLELARAPHAVEVVGYLAWPKVKPKTPFGKTPSLVDIDGCANDVSHETAIIRYLGRELSLDGANEYERARVDELFMQYWHTIRNGGLTHDGQLYSARALKESIERREDAECARFQETHRVNNLSVPARSRQALRVFEEILERNGNSRLVGESLTYVDLALFETLFELAEEDLVPDFATRLNLPRCGEFLTAVAREPPIDRYLKSATRIPRYERPTYAYIGGRHCAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7I0</accession>
    <name>A4S7I0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_43387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421277.1">
        <property type="nucleotide sequence ID" value="XM_001421240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7I0"/>
    <dbReference type="STRING" id="436017.A4S7I0"/>
    <dbReference type="GeneID" id="5005584"/>
    <dbReference type="Gramene" id="ABO99570">
        <property type="protein sequence ID" value="ABO99570"/>
        <property type="gene ID" value="OSTLU_43387"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43387"/>
    <dbReference type="HOGENOM" id="CLU_028567_26_0_1"/>
    <dbReference type="OrthoDB" id="544267at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="18"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="69"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="74"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="115" mass="13715" checksum="7796308CC54B5890" modified="2007-05-15" version="1" fragment="single">MGTRSGQQCAQRWRHKVNPGIRRERWSEEEDEKLKTLKERYGSRWATIAREMGGRTDQQCMGRWRRHLDPTVTRGAWARDEDELLCGLYDEYGPRWSFICQSVPGRTAQQCRARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7T5</accession>
    <name>A4S7T5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421329.1">
        <property type="nucleotide sequence ID" value="XM_001421292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7T5"/>
    <dbReference type="STRING" id="436017.A4S7T5"/>
    <dbReference type="GeneID" id="5005413"/>
    <dbReference type="Gramene" id="ABO99622">
        <property type="protein sequence ID" value="ABO99622"/>
        <property type="gene ID" value="OSTLU_27610"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27610"/>
    <dbReference type="eggNOG" id="ENOG502RZCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_565497_0_0_1"/>
    <dbReference type="OMA" id="HMECLRY"/>
    <dbReference type="OrthoDB" id="497540at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="55271" checksum="DEF232F6411615B0" modified="2007-05-15" version="1">MSLAEEQARRDDEVYDALIRELERVPDDARDAVASFLQDLRRDGVDWYRVGDGGEFDDKESFFRTVHAGACMRAARIMGSGCLKFAREHGCPWNEWTCLFAAMNGNLDCLKYAHENGCPWDNRTCDNAARYGHLDCLEYAHENGCPWNWATCDNAAYYGHLECLEYAHENGCPWDEMTCLFAAKYGHLECLKYAHEHGCPWDVSTCQAAAEYGHLDCLRYAHENGCPWDKRTCDKAAYYGHLECLKYAHEHGCPWDNRTCDNAARYGHLECLEYAHENGCPWDEMTCLFAASNGHLECLKYAHEHGCPWDYWTCYNAAYYGHLECLKYAHEHGCPWDNRTCDNAARYGHLECLKYAHENGCPWDEVTCDNAAYYGHLECLKYARENGCPWNEKTCMDAAENGHLECLKYACAHGCPGSDRYAEALNEVVIPDVDESFGVEVALAFQQNGGEISMREFLPLWVAHREGYRDAHLEIARNWIAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8A0</accession>
    <name>A4S8A0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421729.1">
        <property type="nucleotide sequence ID" value="XM_001421692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8A0"/>
    <dbReference type="STRING" id="436017.A4S8A0"/>
    <dbReference type="GeneID" id="5005666"/>
    <dbReference type="Gramene" id="ABP00023">
        <property type="protein sequence ID" value="ABP00023"/>
        <property type="gene ID" value="OSTLU_27775"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27775"/>
    <dbReference type="eggNOG" id="ENOG502T21M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062941_0_0_1"/>
    <dbReference type="OrthoDB" id="545589at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="42183" checksum="15C78138AC46E648" modified="2007-05-15" version="1">MSEVQARLRAALVAIAEEDVNALYEEEIEDAIATLDDGIRPEEDAEGTVSGACAAVGRLDLLVEARVLGYPWNAKTCANAASSGYFRILKYAHEHGCPWDEKTCMDAADGGHLDCLKYAHENGCPWNTSTCSFAANNGHLECLKYAHERGCPWDVWTCAHAASNGQLECLKYAHKRGCPWDVWTCRDAASNGQLECLKYAHKRGCPWDEETCWYAAKNGHLECLKYAHEQGCPWDAKTCWYAAKYGHLECLKYAHERGCPWDAKTYFCAMSNGNMEVILFLIEREHPHAQSLRLTWEKVAMPILPDADAVIGLEIALSRHRHRHDADGGHVSLREILPFWREHRRLYDEAHRAARVDASLPEIDEERRRVTDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S969</accession>
    <name>A4S969_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422011.1">
        <property type="nucleotide sequence ID" value="XM_001421974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S969"/>
    <dbReference type="STRING" id="436017.A4S969"/>
    <dbReference type="GeneID" id="5005913"/>
    <dbReference type="Gramene" id="ABP00305">
        <property type="protein sequence ID" value="ABP00305"/>
        <property type="gene ID" value="OSTLU_28096"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28096"/>
    <dbReference type="eggNOG" id="KOG0595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_355801_0_0_1"/>
    <dbReference type="OMA" id="VDANERW"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="789" mass="85202" checksum="9C9660EFAC3B2749" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9D3</accession>
    <name>A4S9D3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SDG3502</name>
        <name evidence="15" type="ORF">OSTLU_18587</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421914.1">
        <property type="nucleotide sequence ID" value="XM_001421877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9D3"/>
    <dbReference type="STRING" id="436017.A4S9D3"/>
    <dbReference type="GeneID" id="5006085"/>
    <dbReference type="Gramene" id="ABP00208">
        <property type="protein sequence ID" value="ABP00208"/>
        <property type="gene ID" value="OSTLU_18587"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18587"/>
    <dbReference type="eggNOG" id="KOG4442">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_332722_0_0_1"/>
    <dbReference type="OrthoDB" id="2422440at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
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    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
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    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="15"/>
            <end position="68"/>
        </location>
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        <location>
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            <end position="176"/>
        </location>
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        <location>
            <begin position="178"/>
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        </location>
    </feature>
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        <location>
            <begin position="376"/>
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        </location>
    </feature>
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        <location>
            <begin position="605"/>
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        </location>
    </feature>
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        <location>
            <begin position="376"/>
            <end position="407"/>
        </location>
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        <location>
            <begin position="408"/>
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        </location>
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        <location>
            <begin position="637"/>
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        <location>
            <begin position="686"/>
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        </location>
    </feature>
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        <location>
            <begin position="738"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
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    </evidence>
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        <source>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        </source>
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        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="860" mass="94098" checksum="AAEF473EFF0C2AFC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9U2</accession>
    <name>A4S9U2_OSTLU</name>
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        <recommendedName>
            <fullName evidence="2">Srp40 C-terminal domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">OSTLU_28315</name>
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    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_28315"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28315"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007718">
        <property type="entry name" value="Srp40_C"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="418"/>
            <end position="489"/>
        </location>
    </feature>
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        <location>
            <begin position="50"/>
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        </location>
    </feature>
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        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
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            <end position="209"/>
        </location>
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            <end position="222"/>
        </location>
    </feature>
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            <end position="242"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="494" mass="49819" checksum="6CE971373DE49969" modified="2007-05-15" version="1">MAPPPASAVDDARLGPLLAPVEEYLRACGLNKTVQAMRSERKLKAHRTLVEASEAAGADASEGGAEALVEAWEESRGAKRKANDSSGGSAAKKAKPADSSSSSESGKKSASGSGSKSSSSSSSSSSSSSSSSEEEAKKEKSSSSSSSSSSSSSSEKKEKSSASSSDSESDKSKSKSKSKSSSSSSSSSSSSSSSSSSSEKQEEAKKDDSSSSSSSSSSSSSSSEKKKESSSSSSSSSSSSSSSEKKEEAKKDSSSSSSSSSSSSSSSSSSSSSSSSSEQKKEETKDDASSSSSSSSSSSSSSSSEEKKEEEKDDSSSSSSSSSSSSKSKSKSKSSSSSSSSSSSSSSEKAEEEAKKDDSSSSSSSSSSSSDAKSESKSSSSSSSSSSSSSSSSSDKVRKDSAKGSKSAPPGEKQPGVPFQRVNSAEWLGKKGSWDMSYEGTFGDAGYGAKAQEVLGQVRGARFQHEKNKRKRSYFGGAIDDSAVNSIKFQSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA22</accession>
    <name>A4SA22_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribulose bisphosphate carboxylase small subunit, chloroplastic</fullName>
            <shortName evidence="4">RuBisCO small subunit</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RBCS</name>
        <name evidence="7" type="ORF">OSTLU_28400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Heterohexadecamer of 8 large and 8 small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the RuBisCO small chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422165.1">
        <property type="nucleotide sequence ID" value="XM_001422128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA22"/>
    <dbReference type="STRING" id="436017.A4SA22"/>
    <dbReference type="GeneID" id="5006329"/>
    <dbReference type="Gramene" id="ABP00482">
        <property type="protein sequence ID" value="ABP00482"/>
        <property type="gene ID" value="OSTLU_28400"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28400"/>
    <dbReference type="eggNOG" id="ENOG502QT0M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098114_2_0_1"/>
    <dbReference type="OMA" id="HGNKMFE"/>
    <dbReference type="OrthoDB" id="494915at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016984">
        <property type="term" value="F:ribulose-bisphosphate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009853">
        <property type="term" value="P:photorespiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03527">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.10">
        <property type="entry name" value="Ribulose bisphosphate carboxylase, small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00859">
        <property type="entry name" value="RuBisCO_S_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024681">
        <property type="entry name" value="RuBisCO_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000894">
        <property type="entry name" value="RuBisCO_ssu_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036385">
        <property type="entry name" value="RuBisCO_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31262">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE SMALL CHAIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00101">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00152">
        <property type="entry name" value="RUBISCOSMALL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00961">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55239">
        <property type="entry name" value="RuBisCO, small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="3 4 5" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 5" id="KW-0601">Photorespiration</keyword>
    <keyword evidence="1 4 5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribulose bisphosphate carboxylase small subunit" evidence="6">
        <location>
            <begin position="38"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="169" mass="18858" checksum="4C67357C670C23B1" modified="2007-05-15" version="1">MSAITQASAQVAKTVAVTTGKVANAKSMMIWRPHGNKMFETFSFLPPLSDAEISKQVQYLLNNGWTPCIEFEDSAHAYTDGHGWANMDTSINAGYYDNRYWVMWKLPMYGCQNPDEVIAEINTCIKCFPDCYVRVAGFDNIKQVQCSAFLAHRPASEAACAVDQRQVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA38</accession>
    <name>A4SA38_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422174.1">
        <property type="nucleotide sequence ID" value="XM_001422137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA38"/>
    <dbReference type="GeneID" id="5006336"/>
    <dbReference type="Gramene" id="ABP00491">
        <property type="protein sequence ID" value="ABP00491"/>
        <property type="gene ID" value="OSTLU_28417"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28417"/>
    <dbReference type="HOGENOM" id="CLU_2430993_0_0_1"/>
    <dbReference type="OrthoDB" id="500062at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="91" mass="10181" checksum="92BE52F0D1D81A6B" modified="2007-05-15" version="1">MVIDNAFDDNVKIVFDLTNQAPLTRHGTNILAVDNHLESAEEKKRNSPAWANFVPLDGLTSEFVPFAIGWYGEIGGEALSFIRRIVGFFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAD0</accession>
    <name>A4SAD0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M24 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_28526</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422365.1">
        <property type="nucleotide sequence ID" value="XM_001422328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAD0"/>
    <dbReference type="STRING" id="436017.A4SAD0"/>
    <dbReference type="GeneID" id="5006471"/>
    <dbReference type="Gramene" id="ABP00682">
        <property type="protein sequence ID" value="ABP00682"/>
        <property type="gene ID" value="OSTLU_28526"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28526"/>
    <dbReference type="eggNOG" id="KOG2776">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041451_2_0_1"/>
    <dbReference type="OMA" id="SRMFYSE"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="CDD" id="cd01089">
        <property type="entry name" value="PA2G4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000029">
        <property type="entry name" value="Proliferation-associated 2G4, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="3">
        <location>
            <begin position="31"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="41162" checksum="6C176D1C5658C3D1" modified="2007-05-15" version="1">MADSDSDYASDDESTIDESEFTCENPDVVTKYKIAADCANAAMKEVRAAIAVGAKVVDLCALGDAAIERETAKYYNKKDKDGNKVEKGIAFPTCVSIDNCVCHNSPDASDAKTIEDGASVKIDLGAHVDGYVATTATTVVVGGKPVTGAQADVMKAAELASEIVIRKLRPGASTGEIGGVIEGVAKDFGVNVVEGVMTHNMKRFIIDGNKVILNKSTPEMKADPEEIELYEVYALDIVMSSGEGKPKQRDERETKVYKRAIEKNYQLKMQGSRAVFSEISKRFPTMPFTARALEEKRVNFGLVECCNHGLLHAYPVLYEKDGAAVAHVKSTFLVLKKGNDRITTFEPQEVQSDKSLSDNALVELIATELKPKPKPKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB92</accession>
    <name>A4SB92_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <ecNumber evidence="3">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_8942</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="3"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422577.1">
        <property type="nucleotide sequence ID" value="XM_001422540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB92"/>
    <dbReference type="STRING" id="436017.A4SB92"/>
    <dbReference type="GeneID" id="5006792"/>
    <dbReference type="Gramene" id="ABP00894">
        <property type="protein sequence ID" value="ABP00894"/>
        <property type="gene ID" value="OSTLU_8942"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8942"/>
    <dbReference type="HOGENOM" id="CLU_089358_3_1_1"/>
    <dbReference type="OrthoDB" id="2965at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="entry name" value="Lumazine/riboflavin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058:SF0">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="Lumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="132" mass="14240" checksum="C802626B0BC31F5F" modified="2007-05-15" version="1" fragment="single">ERVRLGVCIGEFHNKLMDRMLEDARVSAEAMGATIDKVVWVPGTYEAPLVVENMLQDPTLDACVVLGYIEKGSTLHGQEMGATFSIIAKQLELEYGKPVGMGIIGPGATAEQAEMRVAYAGNAVRASVRMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBC8</accession>
    <name>A4SBC8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDB1- and CUL4-associated factor 12 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_19107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422593.1">
        <property type="nucleotide sequence ID" value="XM_001422556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBC8"/>
    <dbReference type="STRING" id="436017.A4SBC8"/>
    <dbReference type="GeneID" id="5006812"/>
    <dbReference type="Gramene" id="ABP00910">
        <property type="protein sequence ID" value="ABP00910"/>
        <property type="gene ID" value="OSTLU_19107"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19107"/>
    <dbReference type="eggNOG" id="ENOG502QR7U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020124_0_0_1"/>
    <dbReference type="OMA" id="GGEQYGW"/>
    <dbReference type="OrthoDB" id="10251741at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056151">
        <property type="entry name" value="Beta-prop_DCAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23760">
        <property type="entry name" value="Beta-prop_DCAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DDB1- and CUL4-associated factor 12 beta-propeller" evidence="2">
        <location>
            <begin position="94"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="402" mass="44567" checksum="61E0F20976A2D695" modified="2007-05-15" version="1">MSFCDKAFSCAWLADDLALIGTKDNRLFELEIDRRGRRDAWREIELGREDAYTRNRAMEIAAQWVSRHTPQALRAINVSPPFLAGPYGHGAVRAAASRRGGAHACSVSSTREHIVCSGGPSHNIVGFRRDEETECLVPRMAFSGHDDVVFDVGFIGRDAMASASRDCTVKVWQLPKSPSYDEIRITPSGSVHPIGECTQNERVRGVKVVDRCPARHLATCTSSGHVLQLDAETLSLVHSGYQCRGYLETCCLATDGQIVAVGSRTHIGFVDFRSKNFYASVALPYGDTNSTRSLSFHEGGNLLTIGGGRGLISFYDVRMRKYLVDNGRGRVRQLFNNQYCVPFADNGIFEDEHDDDFYDIEIRDYCLPAIFAHQWDPSGTRLLCAGGPLQSMLHGFFVGVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBG1</accession>
    <name>A4SBG1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_6189</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422771.1">
        <property type="nucleotide sequence ID" value="XM_001422734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBG1"/>
    <dbReference type="SMR" id="A4SBG1"/>
    <dbReference type="STRING" id="436017.A4SBG1"/>
    <dbReference type="GeneID" id="5006828"/>
    <dbReference type="Gramene" id="ABP01088">
        <property type="protein sequence ID" value="ABP01088"/>
        <property type="gene ID" value="OSTLU_6189"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6189"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_7_35_1"/>
    <dbReference type="OMA" id="HDEWTID"/>
    <dbReference type="OrthoDB" id="547759at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000034">
        <property type="entry name" value="Kinase suppressor of Ras 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="9"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP01088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="272" mass="30465" checksum="F783285BE4293AFD" modified="2007-05-15" version="1" fragment="single">FEEIPLDHLEFGRQIGRGAFGEVFRGKYRGTDVAIKRLCVLSDVSDERGLAEFKRELSFLTRLRHRHIVQFIGASTAPPNLCIIMDYCDKGSLYAYLHNPNKTLSAFKVLKWMSEAAKGLVYLHASDIIHRDVKSGNLFIDDGGSIKLGDFGLSKFHTGASTSGGMMSLVGTYQFMAPELLEGQPRYTTAVDVYSFAVVMWECLTREDPFSGLSPMQIVAALLRGERPSLDDASKFAVRLPEEYIAVIARCWRADALERPTMEDIAPELERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBT3</accession>
    <name>A4SBT3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_25941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422914.1">
        <property type="nucleotide sequence ID" value="XM_001422877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBT3"/>
    <dbReference type="STRING" id="436017.A4SBT3"/>
    <dbReference type="GeneID" id="5006972"/>
    <dbReference type="Gramene" id="ABP01273">
        <property type="protein sequence ID" value="ABP01273"/>
        <property type="gene ID" value="OSTLU_25941"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25941"/>
    <dbReference type="eggNOG" id="KOG1036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038526_0_1_1"/>
    <dbReference type="OMA" id="WDSTLHI"/>
    <dbReference type="OrthoDB" id="10262475at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP01273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="33285" checksum="6B333DF58CF7C90F" modified="2007-05-15" version="1">MARRLTLLVTSWDGTARRYACRAREIGDVKSLNSIDLGAPALCGTFVGTDEDAACVGCLDGSVRLVDFKTGAFRVVGAHDDGAVSAVEYDDATKKLFTFGWDRTIRAWDLTKDERGRAVSTTKTAGKCYAADLRDGKIFVATSDGQVLARSSMRFQTRAIAANIRGDGFVAASVEGRVAVEFIRDEENDKRKYAFKCHRKTDDASVGEIVYPVHAVAFHPVHGTFATGGGDGYVNFWDGDAKKRLFQSPRYPTSISALAFSPCGSLLAIASSYAHEERENNKPEDRVFLRETRAEEVTPKSAKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4SC17</accession>
    <name>A4SC17_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HhH-GPD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_36556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422870.1">
        <property type="nucleotide sequence ID" value="XM_001422833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SC17"/>
    <dbReference type="STRING" id="436017.A4SC17"/>
    <dbReference type="GeneID" id="5006929"/>
    <dbReference type="Gramene" id="ABP01229">
        <property type="protein sequence ID" value="ABP01229"/>
        <property type="gene ID" value="OSTLU_36556"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36556"/>
    <dbReference type="HOGENOM" id="CLU_144368_0_0_1"/>
    <dbReference type="OrthoDB" id="10265068at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17466" checksum="908447815528773A" modified="2007-05-15" version="1">MSRLGTPPPPSPMQLLQEYYAHDAWQLLIACALMSRVASGALKHECISNFFAKFPTPSAALAADSQDVFEIIKRLGLFPGRMRTIVEVSTKFLLETGEFEVGLEPELKIYGIGEFGVDSFEIFARGDVRRKPKDCNLQSFCAWQRRHGNGKVKVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQI0</accession>
    <name>A4RQI0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415392.1">
        <property type="nucleotide sequence ID" value="XM_001415355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQI0"/>
    <dbReference type="STRING" id="436017.A4RQI0"/>
    <dbReference type="GeneID" id="5000005"/>
    <dbReference type="Gramene" id="ABO93684">
        <property type="protein sequence ID" value="ABO93684"/>
        <property type="gene ID" value="OSTLU_92059"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92059"/>
    <dbReference type="eggNOG" id="KOG3035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051989_0_2_1"/>
    <dbReference type="OMA" id="RWCARED"/>
    <dbReference type="OrthoDB" id="671439at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="231" mass="26467" checksum="9F2FAA05EAD19B17" modified="2007-05-15" version="1" fragment="single">VFNRGYGGYNSRWCAREDVLDGAFAADARREGRTFLATVMLGTNDATRMRDATAERTNRVRVELEEYAKNMRTIIARAVETSEIVVAMTPPAVDERRRVEAQRERWGEDWVGGPFEDHRPDVEAYGKALVDVVREFQERRHRVYALDLYAETRAAMERGAVLFEDGVHFGEDGQRFVTEKLFQVLDSLDADPSVPDFPYGHEIRNPERAAMSAEEVFDDHEARRPKEALEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQN2</accession>
    <name>A4RQN2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1365 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_39839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415416.1">
        <property type="nucleotide sequence ID" value="XM_001415379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQN2"/>
    <dbReference type="STRING" id="436017.A4RQN2"/>
    <dbReference type="GeneID" id="4999914"/>
    <dbReference type="Gramene" id="ABO93708">
        <property type="protein sequence ID" value="ABO93708"/>
        <property type="gene ID" value="OSTLU_39839"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39839"/>
    <dbReference type="eggNOG" id="ENOG502QVK6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080847_0_0_1"/>
    <dbReference type="OMA" id="DAPPRWF"/>
    <dbReference type="OrthoDB" id="3340520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010775">
        <property type="entry name" value="DUF1365"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973:SF4">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30329" checksum="FDB1CF4908EB2220" modified="2007-05-15" version="1">MTWLGIDDGDGARFYVGEVAHARLKPVRREFKYPLRCAVVDLDAPPRWFAASGQARDHLTADEARERVGLTGAVELLTSPKSFGYAQNPISVYYCRDDAGELRAALAEVTNTPWNERVVFAFDPTPVSNENEATVPKALHVSPFMDMEGEWYVSSTAPGDDVTLRVNVLNHPRYGDYFYASLKAKLDKGRYVRCRNERAGLVNLLKHGCTPHRVAYWIYAQAVAILLAGVSFYAPPGLSNVETRVRAKGDRGGMCPMRPTFRGAPYWPWRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQQ0</accession>
    <name>A4RQQ0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415773.1">
        <property type="nucleotide sequence ID" value="XM_001415736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQQ0"/>
    <dbReference type="STRING" id="436017.A4RQQ0"/>
    <dbReference type="GeneID" id="5000033"/>
    <dbReference type="Gramene" id="ABO94065">
        <property type="protein sequence ID" value="ABO94065"/>
        <property type="gene ID" value="OSTLU_28740"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28740"/>
    <dbReference type="eggNOG" id="ENOG502S47G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1771175_0_0_1"/>
    <dbReference type="OMA" id="REIEWPP"/>
    <dbReference type="OrthoDB" id="1937988at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055330">
        <property type="entry name" value="SECE1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37240">
        <property type="entry name" value="PREPROTEIN TRANSLOCASE SUBUNIT SECE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37240:SF1">
        <property type="entry name" value="PREPROTEIN TRANSLOCASE SUBUNIT SECE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="147" mass="14717" checksum="007EC6F7F074EC23" modified="2007-05-15" version="1">MLARPSRAATPTTASVTARARTTARARTTRVARRARAGVATATADDDEPTTTTNDDGDDDGRAAAESDGAATSEDIGAAIRAAKEAKADDGANIFAGAAEEVGLIEWPTAGGALSTTALVMAGIFGSAGVLLGVNAVLSELSQKLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQV2</accession>
    <name>A4RQV2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415797.1">
        <property type="nucleotide sequence ID" value="XM_001415760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQV2"/>
    <dbReference type="GeneID" id="4999999"/>
    <dbReference type="Gramene" id="ABO94089">
        <property type="protein sequence ID" value="ABO94089"/>
        <property type="gene ID" value="OSTLU_28791"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28791"/>
    <dbReference type="HOGENOM" id="CLU_3053748_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="54" mass="6046" checksum="BC870587DE109BDA" modified="2007-05-15" version="1">MKRNSSVRCAIRAMNVRELLSDDTHGPPKRASAVSETPELMCATFETPRTQKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR05</accession>
    <name>A4RR05_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_8393</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415820.1">
        <property type="nucleotide sequence ID" value="XM_001415783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR05"/>
    <dbReference type="STRING" id="436017.A4RR05"/>
    <dbReference type="GeneID" id="4999491"/>
    <dbReference type="Gramene" id="ABO94112">
        <property type="protein sequence ID" value="ABO94112"/>
        <property type="gene ID" value="OSTLU_8393"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8393"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_4_3_1"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="161" mass="17309" checksum="739600406C57F799" modified="2007-05-15" version="1" fragment="single">RVYLDVSIDGADAERIEFVLYADTSPLAAENFRRMCVGEPSEEYTWVGSKFYRILDRFIDQTGSHTASGSAVNPGKAFDDDPGGLRLKHDRPGLLSVANAGPNTNTGHFSIVMAPAPHLDGSYVIFGEVVDGMEHAWAINKLASSDGEPTGEAKIVRAGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR57</accession>
    <name>A4RR57_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Exocyst complex component Sec3 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415840.1">
        <property type="nucleotide sequence ID" value="XM_001415803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR57"/>
    <dbReference type="GeneID" id="5000003"/>
    <dbReference type="Gramene" id="ABO94132">
        <property type="protein sequence ID" value="ABO94132"/>
        <property type="gene ID" value="OSTLU_13759"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13759"/>
    <dbReference type="eggNOG" id="ENOG502RV79">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_772507_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019160">
        <property type="entry name" value="Sec3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092:SF14">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092">
        <property type="entry name" value="SEC3/SYNTAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09763">
        <property type="entry name" value="Sec3_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec3 coiled-coil" evidence="2">
        <location>
            <begin position="45"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="359" mass="40216" checksum="64E1DC46112D3488" modified="2007-05-15" version="1">MRLAGTTTEEVSSTSTRVLKEEEERVIGELFESTRHATTEGISSLDRILKLELEDADRALSDALESSGSVMASLSAYVSEVERSMEDVNAWSTVFETKLVNMRRNIEIIKGRDDKRDVSNENKRALAAAVRGLLGELELPVGVERAVREHSLDDERGILTIYDALRRLLDFKRKLRYAVRDVSTLHAETNSVSRRDGLPAGIATMRVTVEAREQVEVIAMHAFERVFERLRAIAEVCIVLLVGINLLIFLAGMGAMVDAKKSDERREHVGSNTKVRCMTEINIVTNLTSIAHKRSDLKKFERLFDALSELSPTTADAFARLYCQSCVEVMRCDIVMIMDAIDKQDTEADAINVSSSRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRN7</accession>
    <name>A4RRN7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415601.1">
        <property type="nucleotide sequence ID" value="XM_001415564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRN7"/>
    <dbReference type="GeneID" id="4999602"/>
    <dbReference type="Gramene" id="ABO93893">
        <property type="protein sequence ID" value="ABO93893"/>
        <property type="gene ID" value="OSTLU_29083"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29083"/>
    <dbReference type="eggNOG" id="ENOG502SV68">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1828567_0_0_1"/>
    <dbReference type="OMA" id="LWKPDDK"/>
    <dbReference type="OrthoDB" id="497018at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="141" mass="14812" checksum="2C723956B6B5625C" modified="2007-05-15" version="1">MSSFTLASSAPSKTIARAHARRGAARGARVVVHAAKKKQDATEEDEAKIDFKGLKQLISMGLGTISGDITEINLDDPTRTVVMELEANNFEDKDGKPLNFINNDGFVGEKGESVSVLNYAVPVLLGAASIAGVVATLKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS89</accession>
    <name>A4RS89_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415701.1">
        <property type="nucleotide sequence ID" value="XM_001415664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS89"/>
    <dbReference type="GeneID" id="4999695"/>
    <dbReference type="Gramene" id="ABO93993">
        <property type="protein sequence ID" value="ABO93993"/>
        <property type="gene ID" value="OSTLU_29282"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29282"/>
    <dbReference type="HOGENOM" id="CLU_1167532_0_0_1"/>
    <dbReference type="OrthoDB" id="10527245at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="26183" checksum="22F52969DB351F59" modified="2007-05-15" version="1">MEFHAHDEDSTTNAARALEWFDNAFETRTSGQSYVGAGVRVIENGKILQIEAPIAYEATKKTKRATTIREVTPRDAWLDEGEVRVFLGASAASSAALKIPERATYLGKASESSFINLVDAISRSMDIFIRDGAARVGVCGALLDERGGTRENTLVDLNRKRVELETAKLHERNETVDATKKRLAQESEALSDRVRDAVLYASRAKKAKERVGGGKPTWDILADESDSDSDNDRDVEHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSE4</accession>
    <name>A4RSE4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MFS family transporter: multidrug efflux</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416507.1">
        <property type="nucleotide sequence ID" value="XM_001416470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSE4"/>
    <dbReference type="GeneID" id="5000459"/>
    <dbReference type="Gramene" id="ABO94800">
        <property type="protein sequence ID" value="ABO94800"/>
        <property type="gene ID" value="OSTLU_30287"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30287"/>
    <dbReference type="eggNOG" id="ENOG502QSJF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030532_1_0_1"/>
    <dbReference type="OMA" id="FKWVAIL"/>
    <dbReference type="OrthoDB" id="196955at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047769">
        <property type="entry name" value="MFS_ArsJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23547">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN, GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23547:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="454" mass="48788" checksum="74FE9A0C88761D05" modified="2007-05-15" version="1">MDDGRAAREAKKTFLGPFAVISISYVLFTMTDGAVRMLVLMHAYARGFEAMEVATMFTLYELCGAATNLCAGVAGARFGVRQTLCAGLGLQVVGLGMLFAWDDGWSKREAIAFVTVAQAICGVAKDLTKLGGKTVTKLVTPEDKQKSLFKLVSAITGLKNSFKGVGYFIGAAMLGVSYEAALWMQIALVAAALPFAVFGLDNSLGRVAKANITMSTVFKQSYNMNILSLSRMFLFGSRDLWFEVPLPFFLRSAEGMGWPRSAVGALLAGYIIVYGQLQAWTPQLFLKPLNQNPPNKHVAVIWNVALVSVPLFLGGFIQSSAFQNHSGATTTKTVVIFVGVFVFAYLFAVNSAIHSYLVVKYADGNKVAINVGFYYMANAFGRLIGTIISGALYSYVGSTVEGFAACFWASSAFVLISAALELYIDDDAGGLWCGSIKCIGDDDLAENDVESTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSF6</accession>
    <name>A4RSF6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarylacetoacetase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_6389</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416258.1">
        <property type="nucleotide sequence ID" value="XM_001416221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSF6"/>
    <dbReference type="STRING" id="436017.A4RSF6"/>
    <dbReference type="GeneID" id="5000329"/>
    <dbReference type="Gramene" id="ABO94551">
        <property type="protein sequence ID" value="ABO94551"/>
        <property type="gene ID" value="OSTLU_6389"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6389"/>
    <dbReference type="eggNOG" id="KOG1535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_2_0_1"/>
    <dbReference type="OMA" id="CNKIVAP"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="213" mass="22860" checksum="BF8028DFDC481399" modified="2007-05-15" version="1" fragment="single">VCCVGKNYVEHVGEVDTQMPGISKTAIPELPIIFPKASTSLCGSGTSVELREREDVDYEGELTAIIKRECKDISDDASDVDVISTYVAGWTIANDVTARVLQKSHQQWYLGKSCDGFCPLGPWIVAGHDALPSAASLVTKVNGEIRQNSTVDKMIFSTAELIRCVSKYQTLRAGDAILTGTPSGVGAGFNPKRFLRPGDVVEIEIEGIGALVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSJ1</accession>
    <name>A4RSJ1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416484.1">
        <property type="nucleotide sequence ID" value="XM_001416447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSJ1"/>
    <dbReference type="GeneID" id="5000173"/>
    <dbReference type="Gramene" id="ABO94777">
        <property type="protein sequence ID" value="ABO94777"/>
        <property type="gene ID" value="OSTLU_30238"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30238"/>
    <dbReference type="HOGENOM" id="CLU_2798518_0_0_1"/>
    <dbReference type="OMA" id="MMTITRA"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="68" mass="7642" checksum="E67DCD1AE0F9A5BC" modified="2007-05-15" version="1">MRRSGGSRARIGRASGGGGDDDECDEEDEESECGKKKEKEEEKKEEEEEKEEEEEEEEDADADADAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSM2</accession>
    <name>A4RSM2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_35878</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15 17">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416469.1">
        <property type="nucleotide sequence ID" value="XM_001416432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSM2"/>
    <dbReference type="STRING" id="436017.A4RSM2"/>
    <dbReference type="GeneID" id="5000509"/>
    <dbReference type="Gramene" id="ABO94762">
        <property type="protein sequence ID" value="ABO94762"/>
        <property type="gene ID" value="OSTLU_35878"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35878"/>
    <dbReference type="eggNOG" id="KOG1394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_1"/>
    <dbReference type="OMA" id="TACSIGN"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000027">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004970">
        <property type="entry name" value="PRK06333.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11 15" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="18">
        <location>
            <begin position="8"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="16">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO94762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="422" mass="44687" checksum="5326B02563B41421" modified="2007-05-15" version="1">MARETDPKKRVVITGMGLCSVFGNDYTAYYDKLLSGQSGVAPIDRFDTSDFPTKFAAQIRNFDSEGYIDKKNDRRLDDCLRYALVSGNKALEDAGLDAAALENLDKQRVGVLVGSGMGGLTVFQDGVKALVEKGPKKITPFFIPYAITNMGGAMLAIEKGFMGPNYSISTACATANYAFHAAANHIRNGDAEIMIAGGSEAPIIPVGLGGFVACRALSQNNDDPEGASRPWDKSRDGFVMGEGAGVLIMETLESAKKRGARIHAEYLGGAITCDAHHMTDPRADGLGVSTCIELSIKDAGISVSDINYINAHATSTLVGDVAEVNAVRKVFKDVQNVKMNATKSMIGHCLGAAGGMEAIACIMAIKTGMLHPTLNQNELEPIVEGIDTCANEKKAHTVTAAISNSFGFGGHNSCVIFAPFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT27</accession>
    <name>A4RT27_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">VaoD</name>
        <name evidence="6" type="ORF">OSTLU_119494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416146.1">
        <property type="nucleotide sequence ID" value="XM_001416109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT27"/>
    <dbReference type="STRING" id="436017.A4RT27"/>
    <dbReference type="GeneID" id="5000239"/>
    <dbReference type="Gramene" id="ABO94439">
        <property type="protein sequence ID" value="ABO94439"/>
        <property type="gene ID" value="OSTLU_119494"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119494"/>
    <dbReference type="eggNOG" id="KOG2957">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051277_0_0_1"/>
    <dbReference type="OMA" id="MTYGYMI"/>
    <dbReference type="OrthoDB" id="10250083at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="39429" checksum="D6D5ADD1E60EF2AD" modified="2007-05-15" version="1">MFNAKNGFSEAHVRGCQTKRLTKQNYAELSRCDTLEDIKTYLQTMSDYSEYVRDLQAPVRPVDIIECCRKRQIAEFNICCQQASSPLSNFLEYLTYGYMIDNLVLALNGMLRGRTTEAILEKCSPIGFFDSLSAVVVSSSVQELYRLALVDTPLASYFSSSIKAEDLDELNIELIRNVLYKEYLQDFMVFCNKMDQNTRQLMEKLLSMEADRHAIRITLNSFGTELSKADRRNLYTNFGTMYPDGFARLANCETVDEVKRILVAYPEFRELTKSDDPHYIDRGLRVLELEACGQALDEQFNFAIFYAFVKFQENEINNLMWLTECVAQRQKSSLGEGIVYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT30</accession>
    <name>A4RT30_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein Lysyl hydroxylase fusion protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SmkH</name>
        <name evidence="9" type="ORF">OSTLU_119486</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the terpene cyclase/mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416570.1">
        <property type="nucleotide sequence ID" value="XM_001416533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTX1"/>
    <dbReference type="STRING" id="436017.A4RTX1"/>
    <dbReference type="GeneID" id="5000621"/>
    <dbReference type="Gramene" id="ABO94863">
        <property type="protein sequence ID" value="ABO94863"/>
        <property type="gene ID" value="OSTLU_12302"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12302"/>
    <dbReference type="eggNOG" id="KOG0497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009074_2_0_1"/>
    <dbReference type="OMA" id="YRYRHIS"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016866">
        <property type="term" value="F:intramolecular transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016104">
        <property type="term" value="P:triterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02892">
        <property type="entry name" value="SQCY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000011">
        <property type="entry name" value="Terpene cyclase/mutase family member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032697">
        <property type="entry name" value="SQ_cyclase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002365">
        <property type="entry name" value="Terpene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01787">
        <property type="entry name" value="squalene_cyclas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764:SF20">
        <property type="entry name" value="LANOSTEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="TERPENE CYCLASE/MUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13249">
        <property type="entry name" value="SQHop_cyclase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01016">
        <property type="entry name" value="Prenyltransferase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01074">
        <property type="entry name" value="TERPENE_SYNTHASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Squalene cyclase N-terminal" evidence="7">
        <location>
            <begin position="69"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene cyclase C-terminal" evidence="6">
        <location>
            <begin position="375"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="720" mass="81678" checksum="2A15CC617E1BBD76" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTY1</accession>
    <name>A4RTY1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS family transporter: sugar (Sialic acid)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_49086</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416575.1">
        <property type="nucleotide sequence ID" value="XM_001416538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTY1"/>
    <dbReference type="GeneID" id="5000958"/>
    <dbReference type="Gramene" id="ABO94868">
        <property type="protein sequence ID" value="ABO94868"/>
        <property type="gene ID" value="OSTLU_49086"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49086"/>
    <dbReference type="eggNOG" id="KOG2532">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_5_11_1"/>
    <dbReference type="OMA" id="YNEQSQM"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17380">
        <property type="entry name" value="MFS_SLC17A9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000058">
        <property type="entry name" value="ascorbate transporter, chloroplastic isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000272">
        <property type="entry name" value="Probable anion transporter 6, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044777">
        <property type="entry name" value="SLC17A9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF243">
        <property type="entry name" value="ANION TRANSPORTER 6, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="81"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="506" mass="53984" checksum="5811285DE8270753" modified="2007-05-15" version="1">MGRARGGRGEEARERGDVAARARAERRDRRDAVAASGSSKTTREDRDEGEEDPDEAWAFEFPKSASDVTTLWRGAPSRYRVLFVTVFAFIVCNMDKVNISVAIIPMAREFGWTSTQAGFVQSAFFYGFAASQLPGGYLSTKFGGAKVLPIGMLILSLATIAIPIVGVNEQSIFLSRVLVGLGEGVAPSAATDIIARSVSVGERSRAVGFVFSGFNIGSVLGLGVAPLLIEATNWRTVFAFFGSCGLVWSFWAWKLYGDGGMVDESYKDDGAIASGKSPAEDPPVPWGEFISNPSVRALMYVHFCNNWGFYVLLAWLPTYFTDELGVTLTNASLLTLLPPLANVAMASVAGPTADRLIGSGMEITKVRKTMQAVAFMGPALAMGSAALVDQPVATVGLLTLGLSLGAFSYAGLYSNHQDLSPKYASILLGMTNTCGALPGVIGVPLTGYLIKETENWELSMFVPAMFFYFTGTLVFSKYGSGDRQAFTGQPMPEPGEIPPSCDGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTY9</accession>
    <name>A4RTY9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_30435</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416869.1">
        <property type="nucleotide sequence ID" value="XM_001416832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTY9"/>
    <dbReference type="STRING" id="436017.A4RTY9"/>
    <dbReference type="GeneID" id="5000875"/>
    <dbReference type="Gramene" id="ABO95162">
        <property type="protein sequence ID" value="ABO95162"/>
        <property type="gene ID" value="OSTLU_30435"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30435"/>
    <dbReference type="eggNOG" id="KOG3438">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090381_4_2_1"/>
    <dbReference type="OMA" id="MRIQMYD"/>
    <dbReference type="OrthoDB" id="510325at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07029">
        <property type="entry name" value="RNAP_I_III_AC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033898">
        <property type="entry name" value="RNAP_AC19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF28">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="6">
        <location>
            <begin position="12"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="100" mass="10886" checksum="14EC0C81A2E3C656" modified="2007-05-15" version="1">MTAPRRAATSNEATFTLAGEDHTLANALRHALNGNADVALCGYSVPHPMKREARVRVQTTGANGTTAQGAMRDALLDVISVCDRVREAYEDAERAFERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU78</accession>
    <name>A4RU78_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_30525</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416912.1">
        <property type="nucleotide sequence ID" value="XM_001416875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU78"/>
    <dbReference type="GeneID" id="5000695"/>
    <dbReference type="Gramene" id="ABO95205">
        <property type="protein sequence ID" value="ABO95205"/>
        <property type="gene ID" value="OSTLU_30525"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30525"/>
    <dbReference type="eggNOG" id="KOG4332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034007_2_0_1"/>
    <dbReference type="OMA" id="MNTWPEN"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17487">
        <property type="entry name" value="MFS_MFSD5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672894" description="Molybdate-anion transporter" evidence="13">
        <location>
            <begin position="19"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="452" mass="49487" checksum="87CF0AE9E6E94418" modified="2007-05-15" version="1">MESFYVLTFGALASVCAALEVRKRPTSGKGASLPANFLAFRTNYLVVYALMMAGDWLQGPYVYALYKHYGYGTGDIGKLFIAGFGSSMIFGTIVGSLADRYGRKLAGLTYVATYIASCITKHWSDYGVLMLGRFFGGIATSLLFTAFESWLVSEHFSRNYDPEWLNGTFSKAIFIGNGVVSIVAGLLANYLVTDMNFGPVAPFDAAATFLAIGGVIIALTWTENRGAVNANVSLEASFSAAKHAIFNDKKVLYLGAMQSLFEAAMYSFVFLWTPALSPNDEIIPHGMIFATMMVACMIGSSFAGQLLGDKDLRPEKYMQYVFLASAASLALPIVLKIFPFQANYTPGQSITLEGQITMLGFLVFECLVGIFWPSMMKMRATYVPEEIRSTVMNCFRIPLNLFVCIILYNVALFPLTAMFAMCSLFLVSAAYLQRKLEIITSPPLRGAAPTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUL9</accession>
    <name>A4RUL9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DoxX family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416695.1">
        <property type="nucleotide sequence ID" value="XM_001416658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUL9"/>
    <dbReference type="GeneID" id="5000726"/>
    <dbReference type="Gramene" id="ABO94988">
        <property type="protein sequence ID" value="ABO94988"/>
        <property type="gene ID" value="OSTLU_92457"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92457"/>
    <dbReference type="HOGENOM" id="CLU_1048026_0_0_1"/>
    <dbReference type="OrthoDB" id="497144at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29157" checksum="C2142FA1DBB3519C" modified="2007-05-15" version="1" fragment="single">VRARRRRRRRRRERGKKDARDARDGEDATTRRETRATGETRTREGNDPNGRGSTRDATRRDARSVTDGARSRQKSRAMGKNLIVSILRVVPLALYLRSAACKFAIPIAGCDGALCPVALGKPGDCAPTANTAEQYAWCEHAWTPWANGLIARVPGVSSVAPKIRCSKADGYEFAKIIGALEVLGYLALWTTPARGAFLLTAIMAGAIHFHMTFLKDPIGKLTIQFALLFASATIAMLTTEKKAKKKATTKSKSTRRTTSSRKTKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUP2</accession>
    <name>A4RUP2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_30690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416993.1">
        <property type="nucleotide sequence ID" value="XM_001416956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUP2"/>
    <dbReference type="STRING" id="436017.A4RUP2"/>
    <dbReference type="GeneID" id="5000687"/>
    <dbReference type="Gramene" id="ABO95286">
        <property type="protein sequence ID" value="ABO95286"/>
        <property type="gene ID" value="OSTLU_30690"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30690"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_1"/>
    <dbReference type="OMA" id="AYMVGRC"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20620">
        <property type="entry name" value="CYP132-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="546" mass="59405" checksum="26ACC7036C263556" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUQ3</accession>
    <name>A4RUQ3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nuclear nucleic acid-binding protein C1D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_14690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer and homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416999.1">
        <property type="nucleotide sequence ID" value="XM_001416962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUQ3"/>
    <dbReference type="STRING" id="436017.A4RUQ3"/>
    <dbReference type="GeneID" id="5000708"/>
    <dbReference type="Gramene" id="ABO95292">
        <property type="protein sequence ID" value="ABO95292"/>
        <property type="gene ID" value="OSTLU_14690"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14690"/>
    <dbReference type="eggNOG" id="KOG4835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1456331_0_0_1"/>
    <dbReference type="OMA" id="SADRKEM"/>
    <dbReference type="OrthoDB" id="1421013at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="130"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="181" mass="18999" checksum="CEAE832E963DF044" modified="2007-05-15" version="1">MPAVADDALPEDAREALDEFEAATEAIERALEPFLDADRKALTKELRPLERAEVHCEAARAIVALFGMYLKTLGVDPEKHATAKEMKRVEAYRKKIEETRARLGDGARGASAGGRKASVDVETAAKAIKDGVGSPGDLLKASLAAAGGDKGDGGEDGKEDGGKKRAASANKGKGSKKAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUR9</accession>
    <name>A4RUR9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carotenoid oxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_30717</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416719.1">
        <property type="nucleotide sequence ID" value="XM_001416682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUR9"/>
    <dbReference type="GeneID" id="5000764"/>
    <dbReference type="Gramene" id="ABO95012">
        <property type="protein sequence ID" value="ABO95012"/>
        <property type="gene ID" value="OSTLU_30717"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30717"/>
    <dbReference type="eggNOG" id="KOG1285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016472_6_3_1"/>
    <dbReference type="OMA" id="RVEYTRF"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF138">
        <property type="entry name" value="CAROTENOID OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="524"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="59757" checksum="6844E02FEA850922" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUV4</accession>
    <name>A4RUV4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L10, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL10</name>
        <name evidence="4" type="ORF">OSTLU_30754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416736.1">
        <property type="nucleotide sequence ID" value="XM_001416699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUV4"/>
    <dbReference type="STRING" id="436017.A4RUV4"/>
    <dbReference type="GeneID" id="5000568"/>
    <dbReference type="Gramene" id="ABO95029">
        <property type="protein sequence ID" value="ABO95029"/>
        <property type="gene ID" value="OSTLU_30754"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30754"/>
    <dbReference type="eggNOG" id="KOG0857">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084051_0_0_1"/>
    <dbReference type="OMA" id="HHVIREN"/>
    <dbReference type="OrthoDB" id="10258869at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010224">
        <property type="term" value="P:response to UV-B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018255">
        <property type="entry name" value="Ribosomal_uL16_CS_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_uL16_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003239">
        <property type="entry name" value="PRK04199.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00279">
        <property type="entry name" value="uL16_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005590">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01257">
        <property type="entry name" value="RIBOSOMAL_L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="226" mass="25601" checksum="DFDC1A562C2EF161" modified="2007-05-15" version="1">MARRPAKCYRVIKNKPYPKSRYCRGVPDPKIRIYDAGMKKYSCDAFPACVHLVSFEKEQIGSEAMEAGRIAANKYMVTKAGKEGFHLRVRLHPFHVLRINKMLSCAGADRLQTGMRGAYGKPQGVAARVSIGQIMLSIRTKDVHADKAVEAFRRAKHKFPGRQKIVKSKQWGFTKYSRDDYMKWKDQGRIEPDGVNAKIVQHHGPLAAKPASQLFLNAARRYKVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUY9</accession>
    <name>A4RUY9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C85 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416751.1">
        <property type="nucleotide sequence ID" value="XM_001416714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUY9"/>
    <dbReference type="STRING" id="436017.A4RUY9"/>
    <dbReference type="GeneID" id="5001061"/>
    <dbReference type="Gramene" id="ABO95044">
        <property type="protein sequence ID" value="ABO95044"/>
        <property type="gene ID" value="OSTLU_33951"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33951"/>
    <dbReference type="eggNOG" id="KOG2605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044001_2_2_1"/>
    <dbReference type="OMA" id="FYSYEWC"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22751">
        <property type="entry name" value="OTU_plant_OTU9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF111">
        <property type="entry name" value="OVARIAN TUMOR DOMAIN-CONTAINING DEUBIQUITINATING ENZYME 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="39"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="163" mass="18639" checksum="DEAC1621E8089BCC" modified="2007-05-15" version="1">MRNAASVDFQPKVIVQIPTTDEAATDHTRLDTRLKLYNLREKVVRGDGNCQFRAVADQLFRDQERHAECRAVVVDQLRRASEDYAPYVPEDFDAYVESMAKDTAWGDHITLQAAADAYGVRMCVISSYRDNFLVEITPKTARSARVCWISFWAEVHYNSVYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV83</accession>
    <name>A4RV83_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_24318</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416797.1">
        <property type="nucleotide sequence ID" value="XM_001416760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV83"/>
    <dbReference type="STRING" id="436017.A4RV83"/>
    <dbReference type="GeneID" id="5001068"/>
    <dbReference type="Gramene" id="ABO95090">
        <property type="protein sequence ID" value="ABO95090"/>
        <property type="gene ID" value="OSTLU_24318"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24318"/>
    <dbReference type="eggNOG" id="ENOG502QTKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014689_6_0_1"/>
    <dbReference type="OMA" id="SGCSHEW"/>
    <dbReference type="OrthoDB" id="10250660at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053304">
        <property type="entry name" value="RNA_M5U_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47548">
        <property type="entry name" value="BNAA06G32370D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47548:SF1">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="395"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="441" mass="48427" checksum="8C517D3233276B4F" modified="2007-05-15" version="1">MATRVAGAPRPRVVARASRRATVARSSDGAFDCAHWPRCAGCVDVDAPLRPEAEARARAYFASLDARAGETGETRETHETYRGRATRWRVKAKLAARAHEGETRLGLFARGSHALEPIDDASGCAVSAIAVERAMALVREVCASMDVKGYDETTGNGELRYAQIVAQTRTAGQWDAAKDEDARAAISLVWNARKMTPRAMAVCEEIARRGGDFVHGTWVNAQDARNNVIFNNDGWHHATGERETHSYTPNGAKVFYLPGSFMQANAEAYGELLKRMPRHVPKNARVVEMYAGVGAIGFSLLTNDALGVKSLRCVESSSAVAEAWERTRGELPEDLRGRASLQVEKAERIAVESTKDCDVLIVDPPRKGLDAKLRAVLTDVDGLSDDLQTLLYVSCGFESFMRDSDELLASGVWQIRHHESFVFFPGTNHIEIFAVFSRTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVA1</accession>
    <name>A4RVA1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Peptide deformylase</fullName>
            <ecNumber evidence="3 11">3.5.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PDF1B</name>
        <name evidence="12" type="ORF">OSTLU_33985</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Removes the formyl group from the N-terminal Met of newly synthesized proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 11">
            <text>N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Plastid</location>
            <location evidence="1 11">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="3 11"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417104.1">
        <property type="nucleotide sequence ID" value="XM_001417067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVA1"/>
    <dbReference type="STRING" id="436017.A4RVA1"/>
    <dbReference type="GeneID" id="5001130"/>
    <dbReference type="Gramene" id="ABO95397">
        <property type="protein sequence ID" value="ABO95397"/>
        <property type="gene ID" value="OSTLU_33985"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33985"/>
    <dbReference type="eggNOG" id="KOG3137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_0_1_1"/>
    <dbReference type="OMA" id="VHRNFTI"/>
    <dbReference type="OrthoDB" id="276063at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.45.10:FF:000006">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001159">
        <property type="entry name" value="PRK00150.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458:SF22">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0934">Plastid</keyword>
    <keyword evidence="8 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="26715" checksum="95BC8197A0A43F76" modified="2007-05-15" version="1">MTRCACKVASCSSRVTTTTTRRGAAVVARGKKKGFLFGEVENLSREGEGTKGDDEDAKSVRWSEPLAIAKYPAKCLRAKNAPVETFDKNLERLSKAMFKIMYETVGCGLAAPQVGVNYRMMVYNEAGEPGQGREVVLCNPEIVKFSKEKDLFEEGCLSFPKMYADVERPIGVQIEAQNLKGKKFKMTLEGFEARVFQHEYDHLDGVLYHDRMSPEVRASVQSTLDGFVEAYPGEDSEKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVD4</accession>
    <name>A4RVD4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_30935</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417401.1">
        <property type="nucleotide sequence ID" value="XM_001417364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVD4"/>
    <dbReference type="STRING" id="436017.A4RVD4"/>
    <dbReference type="GeneID" id="5001191"/>
    <dbReference type="Gramene" id="ABO95694">
        <property type="protein sequence ID" value="ABO95694"/>
        <property type="gene ID" value="OSTLU_30935"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30935"/>
    <dbReference type="eggNOG" id="KOG0686">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022348_1_0_1"/>
    <dbReference type="OMA" id="HKILYAR"/>
    <dbReference type="OrthoDB" id="422427at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="224"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="445" mass="49689" checksum="9D4E4054F0E6AD4B" modified="2007-05-15" version="1">MAATSSTAPAIDFDGIFSQYTGNAIVDRLLYVADHARDVGVVTEALRHAKRALEGRVDAFSLKPTTSNGCAYERAMAIAKKREVDASVVGFTKAWLEENARRADGELDKLETGLTDLLTERVKENLRMQYVELGDHYYDRGELKKALECYMRTRDYCSTPKHVVFMCLSVVSVSLEMGNFAHVNVHANKATAALQNMDEDASVRTDQAKLACACGIAALRMGRFREAAIKFTEINVEIGTHYANVCAARDVATYGTLCALASFNREELRDLVLNNQKGAFRAHLETASDIREVVNDFYNSKYTSCFATLDGMREALTLDIHLGAHIDALYKRIRDRALIQYVEPYVTVDLCVMAQAFNTTAEKVQDELARLIEEDKIRAKIDASECTLHALKENPRVKVVEQVIADGERFETETRAALLKMSLLKNDVVSRPEHDGARSHRSLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVG7</accession>
    <name>A4RVG7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cullin family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_45419</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the cullin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417131.1">
        <property type="nucleotide sequence ID" value="XM_001417094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVG7"/>
    <dbReference type="STRING" id="436017.A4RVG7"/>
    <dbReference type="GeneID" id="5001367"/>
    <dbReference type="Gramene" id="ABO95424">
        <property type="protein sequence ID" value="ABO95424"/>
        <property type="gene ID" value="OSTLU_45419"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45419"/>
    <dbReference type="eggNOG" id="KOG2167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004747_7_2_1"/>
    <dbReference type="OMA" id="NYQEQTW"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000001">
        <property type="entry name" value="Cullin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.130:FF:000001">
        <property type="entry name" value="Cullin 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000050">
        <property type="entry name" value="Cullin 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000024">
        <property type="entry name" value="Cullin-4 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="5">
        <location>
            <begin position="347"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="702" mass="79979" checksum="30293BB2C872DC7A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVP1</accession>
    <name>A4RVP1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417179.1">
        <property type="nucleotide sequence ID" value="XM_001417142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVP1"/>
    <dbReference type="STRING" id="436017.A4RVP1"/>
    <dbReference type="GeneID" id="5001211"/>
    <dbReference type="Gramene" id="ABO95472">
        <property type="protein sequence ID" value="ABO95472"/>
        <property type="gene ID" value="OSTLU_24369"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24369"/>
    <dbReference type="HOGENOM" id="CLU_807496_0_0_1"/>
    <dbReference type="OMA" id="CEKERWA"/>
    <dbReference type="OrthoDB" id="10573077at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="344" mass="37159" checksum="C6B71D259B5B4437" modified="2007-05-15" version="1">MAEDARGDDAFDDADAALRTRAMYVKVKFADARGDGDGGEGRRRGDGDGGAVIARFRDAGSRHGKTGDGKSARSASSIRVNGAAVASGEAEITFRREREGAWMSMDEVRFVGDFDFELALDREMWAMGTGRKNEDGTWSMVMTPGASLTRTVSREAERVFYAAAGALPKSPKTAECRVEFGIVGMSQDERVCLVNQIDLPLEKVLGRAQKRIAPVMVGETSAMLPAIDEHTGISTASVSVDAVNAAARQHHKTHWSSFLDRGDMDNLAILSKMRQRYESMMDYQDDYPADPVKLSWFDASLRLGIGVGLGVILGAGLGVGVVVNGFRTISTKRLRSNPKADAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVU1</accession>
    <name>A4RVU1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_37367</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417209.1">
        <property type="nucleotide sequence ID" value="XM_001417172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVU1"/>
    <dbReference type="STRING" id="436017.A4RVU1"/>
    <dbReference type="GeneID" id="5001406"/>
    <dbReference type="Gramene" id="ABO95502">
        <property type="protein sequence ID" value="ABO95502"/>
        <property type="gene ID" value="OSTLU_37367"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37367"/>
    <dbReference type="eggNOG" id="KOG3234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_7_1_1"/>
    <dbReference type="OMA" id="EQHPSMR"/>
    <dbReference type="OrthoDB" id="10264728at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000034">
        <property type="entry name" value="N-alpha-acetyltransferase 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="174" mass="19890" checksum="83F7A70A9B7C4546" modified="2007-05-15" version="1">MTTVRPFACADLFAYNDVNVDALTETYGLAFYLQYLATWPEYFSAATSTFGDVCGYVMGKCEGEGELFHGHVSAVTVAPGYRRQGLAKTLMRELELVTETAHDAYFVDLFVRVSNALAIGMYEKFGYTVYRRVLDYYSGDEDAYDMRKAMRRDVAKKSVVPSKKDWHPWELEWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW01</accession>
    <name>A4RW01_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_36971</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417497.1">
        <property type="nucleotide sequence ID" value="XM_001417460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW01"/>
    <dbReference type="STRING" id="436017.A4RW01"/>
    <dbReference type="GeneID" id="5001358"/>
    <dbReference type="Gramene" id="ABO95790">
        <property type="protein sequence ID" value="ABO95790"/>
        <property type="gene ID" value="OSTLU_36971"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36971"/>
    <dbReference type="eggNOG" id="KOG0616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_5_1"/>
    <dbReference type="OMA" id="RHEEIFA"/>
    <dbReference type="OrthoDB" id="497971at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="41"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="8">
        <location>
            <begin position="301"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="40035" checksum="B361EA926752C922" modified="2007-05-15" version="1">MLHEPPATSLKEKRSSALSGSLRSHSPTIVELQGTKSLNEFEVVDILGQGMVGLVLRAKHKGSGKVCAIKTMPKSQVIENGEEEHCMAERRALEELRHAPFVCNYYASFQDPWALYLVVEDCVGDMFDLFNRSGLPGIGQIKVYTAQVLLGLEYIHSAGYVYRDMKPENLLLRSDGSITIGDFGFAKKLEKGQRAYTICGTPDYLAPELILHQGCTRAADIWAFGILVFEMIAGFPPFRDRQRRDLYKRIVRADFAAVPVPRRMDNDVHEMLSQIFVRDESLRLGIRAPGLGAIKGHAWYETIDWEAVMSGKLRPLHFLPEQLSRADLSSIKDAKTGKFTWMNGPPPNSSEEKFVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWJ3</accession>
    <name>A4RWJ3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417341.1">
        <property type="nucleotide sequence ID" value="XM_001417304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWJ3"/>
    <dbReference type="GeneID" id="5001561"/>
    <dbReference type="Gramene" id="ABO95634">
        <property type="protein sequence ID" value="ABO95634"/>
        <property type="gene ID" value="OSTLU_31356"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31356"/>
    <dbReference type="HOGENOM" id="CLU_2487451_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="87" mass="9801" checksum="839C71A917D0326F" modified="2007-05-15" version="1">MYIDKNYVPVYVNEMEARERAREAKIMETTAPADARRDEEATRLRARLAELEASVREVGARMASLEQPKPSEDAQTASEGEKSRTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWQ0</accession>
    <name>A4RWQ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_92667</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417367.1">
        <property type="nucleotide sequence ID" value="XM_001417330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWQ0"/>
    <dbReference type="STRING" id="436017.A4RWQ0"/>
    <dbReference type="GeneID" id="5001560"/>
    <dbReference type="Gramene" id="ABO95660">
        <property type="protein sequence ID" value="ABO95660"/>
        <property type="gene ID" value="OSTLU_92667"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92667"/>
    <dbReference type="eggNOG" id="KOG4210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_15_1_1"/>
    <dbReference type="OMA" id="MSESIFF"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF11">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="92"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="202"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="30639" checksum="A1CE9934BA03E318" modified="2007-05-15" version="1">MASDDAKAAKKAKKAKKEKKEKKSKRAREDEEARATERGEEKKRSKRDAGGGGANEEKPTTTDDEATEQRDGKSDAAKKDAPAPGTFPTSSTHVYMGNLAWTIDEAALGEAFADCGEIVSVNWFEEKATGKFLGAGVVEFKTAEAAAAAVAATGRLVHKRETPVRFWEKRGNTAEERAAAKAAGGGGRAEIKPMGEKPEGCYTLFMGNLNFQIDDDTIYKFFMDGAGVGPHTIRWLTNKETGEFRGVGFADFSGAEIDAAAKLHGEKCMGRPIRLDWQAPSNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWU9</accession>
    <name>A4RWU9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_31465</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417638.1">
        <property type="nucleotide sequence ID" value="XM_001417601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWU9"/>
    <dbReference type="STRING" id="436017.A4RWU9"/>
    <dbReference type="GeneID" id="5002150"/>
    <dbReference type="Gramene" id="ABO95931">
        <property type="protein sequence ID" value="ABO95931"/>
        <property type="gene ID" value="OSTLU_31465"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31465"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022690_0_0_1"/>
    <dbReference type="OMA" id="DRFWENG"/>
    <dbReference type="OrthoDB" id="42736at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010019">
        <property type="term" value="P:chloroplast-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1350">
        <property type="entry name" value="Pneumovirus matrix protein 2 (M2), zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="PPR" evidence="11">
        <location>
            <begin position="14"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="11">
        <location>
            <begin position="84"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="13">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="12">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="580" mass="65301" checksum="F54362C670D09394" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX02</accession>
    <name>A4RX02_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Meiotic recombination protein SPO11-3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_12516</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the TOP6A family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417667.1">
        <property type="nucleotide sequence ID" value="XM_001417630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX02"/>
    <dbReference type="STRING" id="436017.A4RX02"/>
    <dbReference type="GeneID" id="5002077"/>
    <dbReference type="Gramene" id="ABO95960">
        <property type="protein sequence ID" value="ABO95960"/>
        <property type="gene ID" value="OSTLU_12516"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12516"/>
    <dbReference type="eggNOG" id="KOG2795">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037229_1_0_1"/>
    <dbReference type="OMA" id="IETAGMF"/>
    <dbReference type="OrthoDB" id="5377392at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090628">
        <property type="term" value="P:plant epidermal cell fate specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000387">
        <property type="entry name" value="DNA topoisomerase 6 subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1360.10:FF:000003">
        <property type="entry name" value="DNA topoisomerase 6 subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049333">
        <property type="entry name" value="Topo_VI_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004085">
        <property type="entry name" value="TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF4">
        <property type="entry name" value="DNA TOPOISOMERASE 6 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20768">
        <property type="entry name" value="Topo_VI_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01552">
        <property type="entry name" value="TPISMRASE6A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="15">
        <location>
            <begin position="53"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Type II DNA topoisomerase VI subunit A all-beta" evidence="16">
        <location>
            <begin position="118"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="17">
        <location>
            <begin position="163"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="14">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00082656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO95960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="339" mass="38025" checksum="D73A1A65F77E5391" modified="2007-05-15" version="1">MIAAAKSIVAGDGFEYVLPSRGATDQVYVEALDRIVLKNKTTKANFAAVSSVRKVTILTRVMQLVHGVLSRGIHVTKRDLFYTDVKLFKDQKDSDAVLDDISCMLGCTRNSLHVVASEKGVVVGRLQYKEDGDEIDCTKMGVGGKAIPSNIDKVRDMRTDAKFVLLVEKDAAFMRLAEDRFYNKYPCIIITAKGQPDVATRLFLSKVKRDLKIPVLALVDADPYGLKIISVYMQGSKNMAFDSGNLTTPDIKWLGVRPSDLDKFKIPEQCRLEMTAKDIETGHHMLNEDFIKSNPEWVKEINIMLETKTKAEIQSLSSYGFQYLSEVYLPLKLLEGDWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX63</accession>
    <name>A4RX63_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417699.1">
        <property type="nucleotide sequence ID" value="XM_001417662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX63"/>
    <dbReference type="GeneID" id="5001900"/>
    <dbReference type="Gramene" id="ABO95992">
        <property type="protein sequence ID" value="ABO95992"/>
        <property type="gene ID" value="OSTLU_15331"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15331"/>
    <dbReference type="HOGENOM" id="CLU_1689651_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="156" mass="17670" checksum="35C3A8ED260EB720" modified="2007-05-15" version="1">MKKTIALARAQFTRDEALVEKIRGRGRERARDAAADDDDDDDEGETVTWTKAEVVRLNAYSKYFLAWYLGTIAGIMGFFGFGWTVWGAFFINVGTYFFETMYLRIDLDEIGEGMEFFLDSLASSYGVFVLTWVVVAETLGRSRAQMPTHTIPRFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXC8</accession>
    <name>A4RXC8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-dehydroquinate synthase</fullName>
            <ecNumber evidence="8">4.2.3.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">3-dehydroquinate synthase, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">OSTLU_38791</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the second step in the shikimate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="8"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417727.1">
        <property type="nucleotide sequence ID" value="XM_001417690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXC8"/>
    <dbReference type="STRING" id="436017.A4RXC8"/>
    <dbReference type="GeneID" id="5002134"/>
    <dbReference type="Gramene" id="ABO96020">
        <property type="protein sequence ID" value="ABO96020"/>
        <property type="gene ID" value="OSTLU_38791"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38791"/>
    <dbReference type="eggNOG" id="KOG0692">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001201_0_2_1"/>
    <dbReference type="OMA" id="IAIGMRM"/>
    <dbReference type="OrthoDB" id="197068at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08195">
        <property type="entry name" value="DHQS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1090.10:FF:000002">
        <property type="entry name" value="3-dehydroquinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000001">
        <property type="entry name" value="3-dehydroquinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050071">
        <property type="entry name" value="Dehydroquinate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056179">
        <property type="entry name" value="DHQS_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43622">
        <property type="entry name" value="3-DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43622:SF7">
        <property type="entry name" value="3-DEHYDROQUINATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24621">
        <property type="entry name" value="DHQS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="18" id="KW-0170">Cobalt</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="17" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="3-dehydroquinate synthase N-terminal" evidence="21">
        <location>
            <begin position="73"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="3-dehydroquinate synthase C-terminal" evidence="22">
        <location>
            <begin position="187"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00017684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00056090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00068623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF24621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ABO96020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="368" mass="39644" checksum="432BF7C1010094E1" modified="2007-05-15" version="1">MDGVDVVNVDLGDRSYPIYVGTGLLDDGDALRAHVAGSTALVVTNETIAGLGYLDRTVKALTAKDSKLRVETVVLPDGEEHKNLEVLNAVYTRALETRLDRGTTFVALGGGVIGDMTGYAAASYQRGVKFVQIPTTVMAMVDSSVGGKTGVNHALGKNMIGAFYQPECVLIDIDSLKTLPDREFASGIAEVVKYGLIRDGPFFEWLEANVDKLLARDTQAIAYAVERSCVNKAEVVAADEREGGVRATLNLGHTFGHAIETGLGYGEWLHGEAVSAGMCMAADMSLRLGWIDASLKERTIALLNKCKTPIDVPEKMTVQMFMDLMAVDKKAANGKLRLILLKGELGECVFTGDFDQSKLQETLDAYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXE7</accession>
    <name>A4RXE7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417736.1">
        <property type="nucleotide sequence ID" value="XM_001417699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXE7"/>
    <dbReference type="GeneID" id="5001921"/>
    <dbReference type="Gramene" id="ABO96029">
        <property type="protein sequence ID" value="ABO96029"/>
        <property type="gene ID" value="OSTLU_31668"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31668"/>
    <dbReference type="HOGENOM" id="CLU_947945_0_0_1"/>
    <dbReference type="OMA" id="CTEDVEY"/>
    <dbReference type="OrthoDB" id="10621811at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="294" mass="32301" checksum="DD97393535FCC188" modified="2007-05-15" version="1">MFPSEGDDGAGGFVEEDPVGDYLSVIAAASDCTEDVEYRMACLRWFARAWFDEASTKSSSRPTRRDALNAVAVLDGATRALEKHLASDGDRNAMDGLEKHVVVIAEMLRFIALDDAIDDYFDKDVLGERSLLGAIESICRITRSVLSLYTKSASGDVNESLAIMLVYLLEIVELFTADTNAYEDIGTLLRADIVAIFSMPRAKFIQLWSPHGDIGSRVTRHLLVESHANTPAHTLSLFRIVGNFHDVDLGLVETSVALENLLTLRTTLEGEVGAKAPTQEEMDNFALAIQAWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXG9</accession>
    <name>A4RXG9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417748.1">
        <property type="nucleotide sequence ID" value="XM_001417711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXG9"/>
    <dbReference type="STRING" id="436017.A4RXG9"/>
    <dbReference type="GeneID" id="5001749"/>
    <dbReference type="Gramene" id="ABO96041">
        <property type="protein sequence ID" value="ABO96041"/>
        <property type="gene ID" value="OSTLU_31691"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31691"/>
    <dbReference type="eggNOG" id="ENOG502QTIU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_848341_0_0_1"/>
    <dbReference type="OrthoDB" id="512800at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="328" mass="35214" checksum="A7B43709A7979697" modified="2007-05-15" version="1">MHKYKVQTRTNNASLGLRDLKLDPKDPRCIIASASNGQAYLWDTRLAGDKQTAQLSSLLKTTAIASLVVSDDGHTVIGGDGDKGDLLIWDMRKATSNTSIGGLGDNTQYYSIVAQLSITKLLAKTALATDVKISDSGVHWIGCDPNDCRRLGYHLTNGWSGVLDLMKPCVTHAHCPPAPWLEARQSEVRAENSLEPDALSVPLSDLRRRTPCWLPDGGSFAVGLGVKPGVRVLDFAPTPKSRHWIHGLTIADLEREPAGRYATGNEPVFIETSSKIFSVAAHPYHHGELIAGGESALCLLGYGHVASGRDEDEQGASSEVEIGDAVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXH6</accession>
    <name>A4RXH6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418000.1">
        <property type="nucleotide sequence ID" value="XM_001417963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXH6"/>
    <dbReference type="GeneID" id="5001826"/>
    <dbReference type="Gramene" id="ABO96293">
        <property type="protein sequence ID" value="ABO96293"/>
        <property type="gene ID" value="OSTLU_31699"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31699"/>
    <dbReference type="eggNOG" id="ENOG502QRC4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_644645_0_0_1"/>
    <dbReference type="OMA" id="WPPVQRV"/>
    <dbReference type="OrthoDB" id="1076at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36796">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36796:SF1">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="47353" checksum="4FF5DC22539EB201" modified="2007-05-15" version="1">MRANARVVRARAALERAPRAGARTRARSRRAIHDGRARGRRTNPTTTTRSALERAEADDFEITTRLGSVTLRTERPSASAFAWRASADGGAPESVAASSVEEEVDDGAARVNVYAGRYVHTPSVPPISRNADRGAVMLKEYAGERAAAFAETEVRAYERLLADDDVEIEVDEYGRGPGMLPQKALPIARLVGYFASASIDGDGTRSLWTAQEWHGVRRLSEYARAKQEGKSETKFWPPVQRVQDQPKKARARYVRRAFEQCLKGVWYAHQRGVAHGALDGSTFLCSTFLDTKADDLEVRLINFGCSTLCTPTSVVVDLKAMALVLTELVFASLAAYGPSDATSAEALRRVFVDIHELDFKRIRAYCEEEPDWTDACEFLSDNGGEYWELLRELWQAEELMDGYGVTTNAGALADRAEYLRELLERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXI6</accession>
    <name>A4RXI6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 13">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="9 13">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_12545</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 12 13">Belongs to the peptidase C12 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="9 13"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418005.1">
        <property type="nucleotide sequence ID" value="XM_001417968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXI6"/>
    <dbReference type="STRING" id="436017.A4RXI6"/>
    <dbReference type="MEROPS" id="C12.005"/>
    <dbReference type="GeneID" id="5001800"/>
    <dbReference type="Gramene" id="ABO96298">
        <property type="protein sequence ID" value="ABO96298"/>
        <property type="gene ID" value="OSTLU_12545"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12545"/>
    <dbReference type="eggNOG" id="KOG2778">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018316_0_1_1"/>
    <dbReference type="OMA" id="YIQYEIQ"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09617">
        <property type="entry name" value="Peptidase_C12_UCH37_BAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000003">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017390">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038120">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52049">
        <property type="entry name" value="ULD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 9 12" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 12" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5 9 12" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="15">
        <location>
            <begin position="2"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="229"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10 12">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="12">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="11 12">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038120-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038120-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO96298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="303" mass="33949" checksum="E3AAED6B5C33F399" modified="2007-05-15" version="1">MDWCLIESDPGVFGELVHRIGARGVAFTELYSLDVDELRRNEPIYGLIFLFKWRGGHSSSAVEVDENPPQDLFFASQVIHNACATQAVLSVLLNAEQEVELGETLQTLREFTLDFDAETKGMSISNSDIIRDAHNSFARPEPIVLQSRPAQEDDDVFHFVAYVPRGGSVFELDGLQRGPINHGSFGDGHWLDVAVPAIQRKIASFASNEIKFNLMAVTKDPRIAISQRLEELRSSSTGAADEIAHLQRELEVEEAKVAEWRNDNIRRRHNYIPLVFALLKEVAAAKKLTEALEQAKKRAEAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXS1</accession>
    <name>A4RXS1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_87326</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418043.1">
        <property type="nucleotide sequence ID" value="XM_001418006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXS1"/>
    <dbReference type="GeneID" id="5002118"/>
    <dbReference type="Gramene" id="ABO96336">
        <property type="protein sequence ID" value="ABO96336"/>
        <property type="gene ID" value="OSTLU_87326"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87326"/>
    <dbReference type="eggNOG" id="KOG2508">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017405_1_0_1"/>
    <dbReference type="OMA" id="ANVNVWM"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF100">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="148"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="416" mass="46316" checksum="5859B21CFA791E21" modified="2007-05-15" version="1">MSHQSRSGAKRRKIAVGDDPLLRAFLNQYAGCAVPDHGNPPQIDRVRYASLDADAFETKYVLGRRPVILTDALSDESDLAGANMWTNAFLRDACGGDASTSRVESRDEGANERFGRGKYKSMTFDAFMDKYEARDGGWYLSAGGKAEPFAAPGRLLASETAKSSKGKLPLRPKGVPRSLVPADVNLWMGRNSTSTSSGLHHDYHDNLYVLVRGEKTFKVFSPRDAGRMYTTGKICWVHENGLINYKGASTLQDGDVALATGESALEFRLRKARGDEDEDEPAIGSSDDDFADFDGVDDYDELNQTPEPSDDDSAEEEKRKDDDDEEDPPSFSRIDYDRLDEFPLFKTASAMEFTVKAGEALYLPTGWFHDVSSRDAGEGHVAFNYWFHPPPLGEAWEGRRALWEEDFQRSVLPKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY16</accession>
    <name>A4RY16_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine(9)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_92802</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418092.1">
        <property type="nucleotide sequence ID" value="XM_001418055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY16"/>
    <dbReference type="STRING" id="436017.A4RY16"/>
    <dbReference type="GeneID" id="5002006"/>
    <dbReference type="Gramene" id="ABO96385">
        <property type="protein sequence ID" value="ABO96385"/>
        <property type="gene ID" value="OSTLU_92802"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92802"/>
    <dbReference type="eggNOG" id="KOG2967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068552_0_0_1"/>
    <dbReference type="OMA" id="THTVLNI"/>
    <dbReference type="OrthoDB" id="498646at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052905">
        <property type="term" value="F:tRNA (guanosine(9)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="7">
        <location>
            <begin position="65"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="266" mass="29892" checksum="A745E660BF1576B9" modified="2007-05-15" version="1">MRALGYENVTEVSLCRFGKSFMTTALGSTATAPLEPSVAFTVEDALANAAGKSEKQWEKKSKKKSNVELSERFSNPDALRVAVDVSYEQDSTRARRSVAKQLCECVGIAHREDALAMTYCDFSGPIAEESREFFFSDRWSSVKMDPRSVEEAFDARDVVYMSPDASEVLDEVDASKVYVVGGIVDLATRGMRTSLTRANASSFRCARLPIREHRPEQTHTVLNIDAVVKILCGRHRGESWDDVFDRELPKRQAAERPKRERRERLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY62</accession>
    <name>A4RY62_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418114.1">
        <property type="nucleotide sequence ID" value="XM_001418077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY62"/>
    <dbReference type="STRING" id="436017.A4RY62"/>
    <dbReference type="GeneID" id="5001940"/>
    <dbReference type="Gramene" id="ABO96407">
        <property type="protein sequence ID" value="ABO96407"/>
        <property type="gene ID" value="OSTLU_15593"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15593"/>
    <dbReference type="eggNOG" id="ENOG502QW3A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_585815_0_0_1"/>
    <dbReference type="OMA" id="PFRATHA"/>
    <dbReference type="OrthoDB" id="498998at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36787">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="49819" checksum="8980BCF500EE2A69" modified="2007-05-15" version="1">MATRSGDASPGRREREIKITLKRATPDARGENADVTVRVRSLDVDVGTLKRRFVVNAVWDAPNAESVVLIYGGKVLRDDETLRDAFARGRESVAAYGETAGEGDGRTEMATVDESGTEGEARAAEEYVVHIVVRSARETSAEDSRATTTTTAEGAVNARGGEGDAREEGGHETAVPASEARETTATRGDARDAGASDPGTPAMFRGDVSANAFASPVSMFREDAPRASPSALEHATSPLMNATYQAAYYAAFAALSPSSTPPGPPPLVGVGNFLRVDAASSGEHAANERTGVDDAQQRQRMENGLPPELNIPPGARVRVIHIRIDLKLILKLAMMVFFMSQDASAAKTAMYVGVAILVYLQQTGALAPVARWITGNDNIGRNGLERQNARRNGGEGRNADGAANEDQPIVAPFRATHAAGHTTMPTSYIGEIKIFVYSLFASIFPSWLPPRLHEARDARAAVREHQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY95</accession>
    <name>A4RY95_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_15619</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418348.1">
        <property type="nucleotide sequence ID" value="XM_001418311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY95"/>
    <dbReference type="STRING" id="436017.A4RY95"/>
    <dbReference type="GeneID" id="5002291"/>
    <dbReference type="Gramene" id="ABO96641">
        <property type="protein sequence ID" value="ABO96641"/>
        <property type="gene ID" value="OSTLU_15619"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15619"/>
    <dbReference type="eggNOG" id="KOG3297">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073901_1_1_1"/>
    <dbReference type="OMA" id="LGPTLWW"/>
    <dbReference type="OrthoDB" id="10256606at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013238">
        <property type="entry name" value="RNA_pol_III_Rbc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08292">
        <property type="entry name" value="RNA_pol_Rbc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="84"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="208" mass="22515" checksum="4689BF65A6D95E5D" modified="2007-05-15" version="1">MFQIVALSDGAVKIAPVNLGKSTLEAVTQELESLYVDKVLAECGGLCVTLYSITNISGGTVLAGEGCVCFEVTFKVVLFKPFAGEVIEGTLLSADAHGAHVSIGFFKDIFVPPTNMQAPSEYDDDSKVWMWDYDGELMEMKVGERFRFKVVAVRFPESPKTAEELASLTRESGAAPRDGGDAAFAPMLVIADINEDGLGLCSWWEEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYK6</accession>
    <name>A4RYK6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_24651</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418181.1">
        <property type="nucleotide sequence ID" value="XM_001418144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYK6"/>
    <dbReference type="STRING" id="436017.A4RYK6"/>
    <dbReference type="GeneID" id="5002569"/>
    <dbReference type="Gramene" id="ABO96474">
        <property type="protein sequence ID" value="ABO96474"/>
        <property type="gene ID" value="OSTLU_24651"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24651"/>
    <dbReference type="eggNOG" id="KOG0424">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_12_0_1"/>
    <dbReference type="OMA" id="DHPHGFI"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019787">
        <property type="term" value="F:ubiquitin-like protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="13">
        <location>
            <begin position="4"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="173" mass="19099" checksum="F9A0645719AC7E83" modified="2007-05-15" version="1">MSSLITARLAQERKDWRKDHPHGFIAKPSTKKDKNGDTTTDLTVWNCAIPGKADTPWAGGSYPLRLEFGNDYPAKPPRVAFPAGFFHPNVYPTGKVCLSILNEDKGWKPSVSIKQILIGVQDLLDSPNMSDPAQQEAYDQLRRSKATYLKRIKEQAKKFGSASGGAGDEIIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYM7</accession>
    <name>A4RYM7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418192.1">
        <property type="nucleotide sequence ID" value="XM_001418155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYM7"/>
    <dbReference type="GeneID" id="5002172"/>
    <dbReference type="Gramene" id="ABO96485">
        <property type="protein sequence ID" value="ABO96485"/>
        <property type="gene ID" value="OSTLU_15714"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15714"/>
    <dbReference type="HOGENOM" id="CLU_881070_0_0_1"/>
    <dbReference type="OMA" id="ESAWTHE"/>
    <dbReference type="OrthoDB" id="498669at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="316" mass="35756" checksum="A46988CC56353282" modified="2007-05-15" version="1">MTMPMTTLASASRSRPGTTTTTTTTTARGGRMRASSRHSSRRGDRVVGRVAEGGKSERGRMKDEEEYAKFVEEARTWTAYDPEAVGGENATPPWEKELQDAMREGPWPCWDADIPESDFVDEPRFMSFTKPPEKYDPFKEKIVNYKAKVKEEQKRAVAKTREEVKSQRFMSMAGDIRLKNKYEDDESAWDHEKIVELINFPDDIRHKMMSVSVEVYDPRFPYDFTGMGAPPLTTEEFLESIGRLQPDGESDLDRVAKLAEKYGSKVPELAEEDPAAILQTRSTFELQNAMDIGDEGGVEISKTEISDLVDSDDELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYS6</accession>
    <name>A4RYS6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418444.1">
        <property type="nucleotide sequence ID" value="XM_001418407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYS6"/>
    <dbReference type="GeneID" id="5002309"/>
    <dbReference type="Gramene" id="ABO96737">
        <property type="protein sequence ID" value="ABO96737"/>
        <property type="gene ID" value="OSTLU_32131"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32131"/>
    <dbReference type="HOGENOM" id="CLU_2709247_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="7707" checksum="4EDF3905D5642261" modified="2007-05-15" version="1">MRGALSSTLYTLGATAVCVSIGAKHGVIEVRTERIRDETARTLCAGTLRASDAAVDLAFELGTRIARELGSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYU6</accession>
    <name>A4RYU6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_41450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418455.1">
        <property type="nucleotide sequence ID" value="XM_001418418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYU6"/>
    <dbReference type="STRING" id="436017.A4RYU6"/>
    <dbReference type="GeneID" id="5002378"/>
    <dbReference type="Gramene" id="ABO96748">
        <property type="protein sequence ID" value="ABO96748"/>
        <property type="gene ID" value="OSTLU_41450"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41450"/>
    <dbReference type="eggNOG" id="KOG0322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1535048_0_0_1"/>
    <dbReference type="OMA" id="FERHEEG"/>
    <dbReference type="OrthoDB" id="7668193at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="141"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="175" mass="19007" checksum="B25A3593065C5AC0" modified="2007-05-15" version="1">MCVRFVRSTHLLAGYEDGTVILWALNFESGVGEIVFRRRAHGETALCVDVDAGGEGAVTGGADGVLVRYAIEFVTKSEVNVRVLRTHGPYTDVVSASSKQPGVSACSIRRDGKIVACGCWDGKIRVFEYKARSKGRLLAVLKYHDATVTDVLFAPDDSFLVSTSRDGTVAMWNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYZ4</accession>
    <name>A4RYZ4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome maturation factor UMP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the POMP/UMP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418479.1">
        <property type="nucleotide sequence ID" value="XM_001418442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYZ4"/>
    <dbReference type="STRING" id="436017.A4RYZ4"/>
    <dbReference type="GeneID" id="5002346"/>
    <dbReference type="Gramene" id="ABO96772">
        <property type="protein sequence ID" value="ABO96772"/>
        <property type="gene ID" value="OSTLU_32196"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32196"/>
    <dbReference type="eggNOG" id="KOG3061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134690_1_0_1"/>
    <dbReference type="OMA" id="DFHCIND"/>
    <dbReference type="OrthoDB" id="15001at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008012">
        <property type="entry name" value="Ump1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828:SF3">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="14965" checksum="DD8EA80C67EF017A" modified="2007-05-15" version="1">MDDEIKFLRRPVDTLRLGLAAARDVGASSAKHPVQVMQEERASGAEYAKKLETMARAHGGAIPAKLDAERQILTDVERLPGPVPSKRLGLQILTGDIDRFGFEDYLNPEDMRTEGPRSDAHAVMEAKLGLGPSVGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZA5</accession>
    <name>A4RZA5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_41212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418296.1">
        <property type="nucleotide sequence ID" value="XM_001418259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZA5"/>
    <dbReference type="STRING" id="436017.A4RZA5"/>
    <dbReference type="GeneID" id="5002508"/>
    <dbReference type="Gramene" id="ABO96589">
        <property type="protein sequence ID" value="ABO96589"/>
        <property type="gene ID" value="OSTLU_41212"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41212"/>
    <dbReference type="eggNOG" id="KOG1257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011405_5_1_1"/>
    <dbReference type="OMA" id="EVPVTPW"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004473">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF90">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="5">
        <location>
            <begin position="75"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="4">
        <location>
            <begin position="266"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="61688" checksum="510F5F5A294ED730" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZD9</accession>
    <name>A4RZD9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="9">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_15917</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="9"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418558.1">
        <property type="nucleotide sequence ID" value="XM_001418521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZD9"/>
    <dbReference type="STRING" id="436017.A4RZD9"/>
    <dbReference type="GeneID" id="5002366"/>
    <dbReference type="Gramene" id="ABO96851">
        <property type="protein sequence ID" value="ABO96851"/>
        <property type="gene ID" value="OSTLU_15917"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15917"/>
    <dbReference type="eggNOG" id="KOG0987">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001613_7_1_1"/>
    <dbReference type="OMA" id="SSAWESC"/>
    <dbReference type="OrthoDB" id="508102at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="10">
        <location>
            <begin position="55"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="11">
        <location>
            <begin position="337"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="628" mass="70069" checksum="3BBC71A9F6D9D75E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZT6</accession>
    <name>A4RZT6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hydroxyproline O-arabinosyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_32501</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418856.1">
        <property type="nucleotide sequence ID" value="XM_001418819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZT6"/>
    <dbReference type="STRING" id="436017.A4RZT6"/>
    <dbReference type="GeneID" id="5002679"/>
    <dbReference type="Gramene" id="ABO97149">
        <property type="protein sequence ID" value="ABO97149"/>
        <property type="gene ID" value="OSTLU_32501"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32501"/>
    <dbReference type="eggNOG" id="ENOG502SHVJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_614507_0_0_1"/>
    <dbReference type="OMA" id="PMYGEEH"/>
    <dbReference type="OrthoDB" id="495562at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF17">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="8">
        <location>
            <begin position="126"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="446" mass="51301" checksum="BB5A97F7C4291397" modified="2007-05-15" version="1">MDDISSRDGYDAEEWRRIRDAETPEDECHELPQSDYWGPQPLTQSVEGVSITVARDCCELCKKTAKCQFWRHDPAKPNECFTGTLINDYLPPMYGEEHNRKTTSGVLYPKKSRYDAESTELKTCVHTMITSNGSPYMNWQTRVFYQTWKKAASEKDSVLRHFTRILHRSTDDSLMDLVPTWRADPTHVECDNSCDYAVKDRARAIAEWMKSDDSRRCSHILMAETDYLFIRSPPPSVLLAKGISYGFLFGYIVPSYPDAKEASVLLHDVSKDGPLKDVYQTGNAPQCIHRDDLERVAPVWADKVEFGESNEVVKRVFGWVRDMYAWSFAAAAVRPKLEFELPPVPFQKLMIQPPADIAIGQSSVMHYTWGAIISNKEDHEVWRFDKREYLGSWDSLKKIEPLPPWDAEQEFKLQDKKRIQKSQYEVLDKMVEIFNEAVDAVVAGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4S024</accession>
    <name>A4S024_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418669.1">
        <property type="nucleotide sequence ID" value="XM_001418632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S024"/>
    <dbReference type="GeneID" id="5002639"/>
    <dbReference type="Gramene" id="ABO96962">
        <property type="protein sequence ID" value="ABO96962"/>
        <property type="gene ID" value="OSTLU_32592"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32592"/>
    <dbReference type="HOGENOM" id="CLU_462644_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="538"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="590" mass="66320" checksum="735D7EBF34021664" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S181</accession>
    <name>A4S181_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_16406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419320.1">
        <property type="nucleotide sequence ID" value="XM_001419283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S181"/>
    <dbReference type="STRING" id="436017.A4S181"/>
    <dbReference type="GeneID" id="5003267"/>
    <dbReference type="Gramene" id="ABO97613">
        <property type="protein sequence ID" value="ABO97613"/>
        <property type="gene ID" value="OSTLU_16406"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16406"/>
    <dbReference type="eggNOG" id="KOG2198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1051263_0_0_1"/>
    <dbReference type="OrthoDB" id="1938384at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="265" mass="28969" checksum="183AE69C14FA44C0" modified="2007-05-15" version="1">MQLLECARYGASGGEGVVHANDAHPGRVGTLLDAIDRHARAGCERAGLFVTRSFGQDLHFPLFVSGGDLKRALKNICGMDDDAKRRAALLAIGGYTHVLADVPCSGDGTIRKDADALVRWHPGIGNALHSTQLAVARRCAQLLKPGGSMVYSTCTFNPIEDEAVVQTLLMDQDLSLELEELDLPLKGRPGMYSWKVGEHINASSEDEDVSIQWFASFDDAVRKSSSEFVKTMWPLDAPAHAEALRLELCARFLPHDDNTVEKEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1C2</accession>
    <name>A4S1C2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MutL C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_9885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419340.1">
        <property type="nucleotide sequence ID" value="XM_001419303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1C2"/>
    <dbReference type="STRING" id="436017.A4S1C2"/>
    <dbReference type="GeneID" id="5003086"/>
    <dbReference type="Gramene" id="ABO97633">
        <property type="protein sequence ID" value="ABO97633"/>
        <property type="gene ID" value="OSTLU_9885"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9885"/>
    <dbReference type="eggNOG" id="KOG1977">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3056857_0_0_1"/>
    <dbReference type="OrthoDB" id="498237at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF47">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="7055" checksum="022146FB1E7542FE" modified="2007-05-15" version="1" fragment="single">PRPLHRLLASKACRGAIMFGDTLNRDECEAIVRALRLTQMPFACAHGRPTCAPLARVPNRATLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1C8</accession>
    <name>A4S1C8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HTA3502</name>
        <name evidence="13" type="ORF">OSTLU_12803</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419342.1">
        <property type="nucleotide sequence ID" value="XM_001419305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1C8"/>
    <dbReference type="STRING" id="436017.A4S1C8"/>
    <dbReference type="GeneID" id="5003293"/>
    <dbReference type="Gramene" id="ABO97635">
        <property type="protein sequence ID" value="ABO97635"/>
        <property type="gene ID" value="OSTLU_12803"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12803"/>
    <dbReference type="eggNOG" id="KOG1756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062828_3_3_1"/>
    <dbReference type="OMA" id="KFQMAGR"/>
    <dbReference type="OrthoDB" id="496320at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000009">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="11">
        <location>
            <begin position="8"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="12">
        <location>
            <begin position="90"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="12791" checksum="037A3335D3E1C0A3" modified="2007-05-15" version="1">MSGRGKGKTGKKATSRSAKAGLQFPVGRVARYLKAGKYATRVGAGAPVYLAAVLEYLAAEVLELAGNASRDNKKSRIVPRHIQLAIRNDEELSKLLGTVTIAAGGVLPNIHSVLLPKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1F6</accession>
    <name>A4S1F6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein TIC 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_16462</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in protein precursor import into chloroplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Tic20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419357.1">
        <property type="nucleotide sequence ID" value="XM_001419320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1F6"/>
    <dbReference type="STRING" id="436017.A4S1F6"/>
    <dbReference type="GeneID" id="5003244"/>
    <dbReference type="Gramene" id="ABO97650">
        <property type="protein sequence ID" value="ABO97650"/>
        <property type="gene ID" value="OSTLU_16462"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16462"/>
    <dbReference type="eggNOG" id="ENOG502QUSD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094758_0_0_1"/>
    <dbReference type="OMA" id="HAFPFAP"/>
    <dbReference type="OrthoDB" id="414558at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005691">
        <property type="entry name" value="Tic20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510:SF5">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16166">
        <property type="entry name" value="TIC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="176" mass="19393" checksum="69C65E1F88EF0F58" modified="2007-05-15" version="1">MMGQGRGQNKNAPEEEYDYSERAIAALVYMLPLLDSLKYSKFLLLQFPAFSLALLPLSPLISLWFNLGFLQIAVFFATYLGVVQNQNMKRFVRFNAQQAVLLDILLIVPDLLTRTFQGIDGSGPTGGAGLQAEIIFFNSVFLFTYICCTVGAVGSTAGKEIKLPLIGDAAEMQQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1S6</accession>
    <name>A4S1S6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Reticulon-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_33205</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Endoplasmic reticulum membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419199.1">
        <property type="nucleotide sequence ID" value="XM_001419162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1S6"/>
    <dbReference type="STRING" id="436017.A4S1S6"/>
    <dbReference type="GeneID" id="5003197"/>
    <dbReference type="Gramene" id="ABO97492">
        <property type="protein sequence ID" value="ABO97492"/>
        <property type="gene ID" value="OSTLU_33205"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33205"/>
    <dbReference type="HOGENOM" id="CLU_678615_0_0_1"/>
    <dbReference type="OrthoDB" id="783438at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003388">
        <property type="entry name" value="Reticulon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02453">
        <property type="entry name" value="Reticulon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50845">
        <property type="entry name" value="RETICULON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Reticulon" evidence="8">
        <location>
            <begin position="162"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="406" mass="45192" checksum="4E6C459B9DE0CC3F" modified="2007-05-15" version="1">MFENFASTSRSTLERGASSERERRPFADLRNDASAGRGDSGASRASTVELRRGARWARDDFVETPAALRKRVESLDAFGTVRRTEDATPASFAAETTTDGGRMTEEFDRKRALTPYYGEMRGERVACGVVQTPETESVGEAMRRETRRRAEASEGYGARGAVLEVLLWRDAARSAIHFTIGMTMLLFVRLAPRSTVSGVSLTAYASMAYLAYKYVWAVMFPRLSYGLELNDRAVGDMAQRWAISFNAWASRHRGVLAGRDNSAVFRTFLALYAVSALGHVMSAWAVATTLWVGAFTVPPFFDAYRYSITNAYVTAHIFTSSRFNALSAPKRWIGGLLLGAFAFASVNVKARFCLSFLALVAFRMFRETHVKELAAFENIVRSASRRVSRSMNEFAMILSPAARHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1S9</accession>
    <name>A4S1S9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_33208</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419201.1">
        <property type="nucleotide sequence ID" value="XM_001419164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1S9"/>
    <dbReference type="STRING" id="436017.A4S1S9"/>
    <dbReference type="GeneID" id="5003115"/>
    <dbReference type="Gramene" id="ABO97494">
        <property type="protein sequence ID" value="ABO97494"/>
        <property type="gene ID" value="OSTLU_33208"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33208"/>
    <dbReference type="eggNOG" id="ENOG502QR14">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041456_1_1_1"/>
    <dbReference type="OMA" id="MPEHEGE"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF236">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="111"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="210" mass="23594" checksum="55B892A3A9FE2FC9" modified="2007-05-15" version="1">MGAPTRGAARAPRATLPELDARADARPIRPRHLVANEIIVVDDALTARDCARIVDAIGDDFAASSSRGPRHGEARRRNGRFAETSEAFARRLYERANVAATFGFEIDDAVGLNPNIRVYRYRAREHFGAHVDERVTALGRRSKYTALFYLSEDVEGGSTIFYDEVGEERCRVRPKIGRALYFRHGADMPEHEGEEVREGTKYVLRSDVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1W5</accession>
    <name>A4S1W5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419221.1">
        <property type="nucleotide sequence ID" value="XM_001419184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1W5"/>
    <dbReference type="GeneID" id="5003136"/>
    <dbReference type="Gramene" id="ABO97514">
        <property type="protein sequence ID" value="ABO97514"/>
        <property type="gene ID" value="OSTLU_33244"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33244"/>
    <dbReference type="HOGENOM" id="CLU_2007779_0_0_1"/>
    <dbReference type="OrthoDB" id="10560065at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="124" mass="13186" checksum="1638E47EF7DE3717" modified="2007-05-15" version="1">MYDADEARTFGRQHGSTEVLSALTTEEARTIPARAIAVHAGEKSESYVRGEDGELYEMMACGRTRTRAHAPSSPRAVVTVHSSEVNEDAGAIGAAGRRYRGSFNSLLLLEAQELSTGRASSASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S252</accession>
    <name>A4S252_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_34894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419687.1">
        <property type="nucleotide sequence ID" value="XM_001419650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S252"/>
    <dbReference type="STRING" id="436017.A4S252"/>
    <dbReference type="GeneID" id="5003624"/>
    <dbReference type="Gramene" id="ABO97980">
        <property type="protein sequence ID" value="ABO97980"/>
        <property type="gene ID" value="OSTLU_34894"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34894"/>
    <dbReference type="eggNOG" id="KOG0509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_18_9_1"/>
    <dbReference type="OrthoDB" id="590877at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039323">
        <property type="entry name" value="ANKRD_45/46/60"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677:SF4">
        <property type="entry name" value="USHER SYNDROME TYPE-1G PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="166" mass="18105" checksum="7FEC945B6ABD1C61" modified="2007-05-15" version="1" fragment="single">MSGFEKHEAFAIEAVKALLPHVENECTQDDYGRTALSVAAQHGVLPIVQHLVSEFTPPNEEDTVEVYVNLRDKTRNRPVHWACAYGRGDVVDFLLKNGADPTLKNDNKDNALHCAVRGGDVKCVELLLKSHGALTKDKNAQQQTPGELAAARGQPTIAKLLKATVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Z3</accession>
    <name>A4S2Z3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="14">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_34625</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the BRE1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="14"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419830.1">
        <property type="nucleotide sequence ID" value="XM_001419793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Z3"/>
    <dbReference type="STRING" id="436017.A4S2Z3"/>
    <dbReference type="GeneID" id="5003889"/>
    <dbReference type="Gramene" id="ABO98123">
        <property type="protein sequence ID" value="ABO98123"/>
        <property type="gene ID" value="OSTLU_34625"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34625"/>
    <dbReference type="eggNOG" id="KOG0978">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1920617_0_0_1"/>
    <dbReference type="OMA" id="CFECLAT"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 14 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="79"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO98123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="132" mass="14981" checksum="1E98CCF5FE983CBE" modified="2007-05-15" version="1">MEKQVVEVRDKLAASEKNVATLTKRSESEIAKLEAEKAARVKAETTAASLKKKCDRLLKEGGTKDLHAEVDAYKTLMNCNVCQGERQKAVIITRCWHMFCEECINKRVVSRQRKCPGCSLPFAESEVQRIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3B1</accession>
    <name>A4S3B1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YchJ-like middle NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419888.1">
        <property type="nucleotide sequence ID" value="XM_001419851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3B1"/>
    <dbReference type="GeneID" id="5004124"/>
    <dbReference type="Gramene" id="ABO98181">
        <property type="protein sequence ID" value="ABO98181"/>
        <property type="gene ID" value="OSTLU_25994"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25994"/>
    <dbReference type="HOGENOM" id="CLU_1491419_0_0_1"/>
    <dbReference type="OrthoDB" id="525903at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048469">
        <property type="entry name" value="YchJ-like_M"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17775">
        <property type="entry name" value="YchJ_M-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YchJ-like middle NTF2-like" evidence="2">
        <location>
            <begin position="50"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="181" mass="19555" checksum="AF1BBAD8873505D2" modified="2007-05-15" version="1">MRERDDASEERTGKQRGASGCACGKDASVAYEACCGRAHGDANAAAALAAEDVMRARFTAYVVGDAQYIVSSTHEESKDRARESLLRDAENTIKRIRFHSFRAKRSSEKDGEAYVTYEADYTQGKGRGKMKTLAERARLRRDAETGGWKFVDAVALGANASLDDAGDAAAPGAPDPSRRPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3B7</accession>
    <name>A4S3B7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420066.1">
        <property type="nucleotide sequence ID" value="XM_001420029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3B7"/>
    <dbReference type="GeneID" id="5004206"/>
    <dbReference type="Gramene" id="ABO98359">
        <property type="protein sequence ID" value="ABO98359"/>
        <property type="gene ID" value="OSTLU_26000"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26000"/>
    <dbReference type="HOGENOM" id="CLU_2709242_0_0_1"/>
    <dbReference type="OrthoDB" id="505899at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.442.10">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036639">
        <property type="entry name" value="Cyt_c_oxidase_su4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009515">
        <property type="entry name" value="DUF1138"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34267:SF17">
        <property type="entry name" value="OS06G0114500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34267">
        <property type="entry name" value="OS11G0161033 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06592">
        <property type="entry name" value="DUF1138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81406">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="7605" checksum="99950247F0332112" modified="2007-05-15" version="1">MTSASIAQVASATAALCGAAGVTYYAVNVAKVFGGDPLPSTMTKEWEDATKARMKAWPREGSATPVVLEPMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3J5</accession>
    <name>A4S3J5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420106.1">
        <property type="nucleotide sequence ID" value="XM_001420069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3J5"/>
    <dbReference type="GeneID" id="5004060"/>
    <dbReference type="Gramene" id="ABO98399">
        <property type="protein sequence ID" value="ABO98399"/>
        <property type="gene ID" value="OSTLU_26076"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26076"/>
    <dbReference type="HOGENOM" id="CLU_1819096_0_0_1"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="14370" checksum="1DE3AEABE3FD2C9C" modified="2007-05-15" version="1">MTFADAATRAVRALEIRETDSVCVPVPLGHAMGFGFGALAAFAAGARLVLPPTIGSAADGAAAREAMCAATLDAIRSEKCTLAVVDSHVTRAAAERDLGADAGYDHFRGGLIKVGSGDAIGVAESVKFLGAELLTVGKPKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3K3</accession>
    <name>A4S3K3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_38146</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419934.1">
        <property type="nucleotide sequence ID" value="XM_001419897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3K3"/>
    <dbReference type="STRING" id="436017.A4S3K3"/>
    <dbReference type="GeneID" id="5004064"/>
    <dbReference type="Gramene" id="ABO98227">
        <property type="protein sequence ID" value="ABO98227"/>
        <property type="gene ID" value="OSTLU_38146"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38146"/>
    <dbReference type="eggNOG" id="KOG0176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_4_2_1"/>
    <dbReference type="OMA" id="NHYFTYN"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000054">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="25823" checksum="C9DA38C847663BEF" modified="2007-05-15" version="1">MFQTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIAIKTREGVVLAVEKRATSPLMDASSLEKIAEIDAHVGCAVSGLTADAWTMVEHGRAECQNHYFTYNEPMPVLSCTTSLCELAMSFAGEGEKRMSRPFGVALLVAGKDEDGYHLVHTDPSGTAVQYKAKAIGSGSEGAQTALQEEYRDDLTLKEAETLALKTLKAVMEEKVNTTNVDMARVAPAYVKYSDAAIQEIIDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S492</accession>
    <name>A4S492_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_5433</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420231.1">
        <property type="nucleotide sequence ID" value="XM_001420194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S492"/>
    <dbReference type="STRING" id="436017.A4S492"/>
    <dbReference type="GeneID" id="5004295"/>
    <dbReference type="Gramene" id="ABO98524">
        <property type="protein sequence ID" value="ABO98524"/>
        <property type="gene ID" value="OSTLU_5433"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5433"/>
    <dbReference type="eggNOG" id="KOG1865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008279_10_0_1"/>
    <dbReference type="OMA" id="QQANKAW"/>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000119">
        <property type="entry name" value="Ubiquitin specific peptidase 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF758">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="2"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="316" mass="34988" checksum="F8A65C75B8FCBF59" modified="2007-05-15" version="1" fragment="single">GAGLANLGNTCFLNSVLQCLTHTPALANFALRGEHKKYKTGGSFNALYEIGEHVARALNSSGRTIAPTALVKNLRALSKTFRKGRQEDAHELARCLLDAMHKKCVEVVKPKISPNSARAETSFVWKVFGGRLRSQVNCKTCGRNSETFDPFLDLSLEVGRAKSVLGAFKMFTHTEVLDGDNKYRCEGKSANSKSHLTKASKQFTVNQAPNVLALQLKRFAYVPFGRGKLNHFVEYPLELDITPYTSDEGLTSRGKAVYDLYGVLVHAGNSSNSGHYYCFVKVATGTWCLMDDDEITSVSEKVVLKQQAYLLFYARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4G7</accession>
    <name>A4S4G7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_17265</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420433.1">
        <property type="nucleotide sequence ID" value="XM_001420396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4G7"/>
    <dbReference type="STRING" id="436017.A4S4G7"/>
    <dbReference type="GeneID" id="5004463"/>
    <dbReference type="Gramene" id="ABO98726">
        <property type="protein sequence ID" value="ABO98726"/>
        <property type="gene ID" value="OSTLU_17265"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17265"/>
    <dbReference type="eggNOG" id="KOG3111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054856_0_1_1"/>
    <dbReference type="OMA" id="SDTVHKC"/>
    <dbReference type="OrthoDB" id="1927044at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006163">
        <property type="term" value="P:purine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000191">
        <property type="entry name" value="ribulose-phosphate 3-epimerase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00057323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="204" mass="21076" checksum="B6C3ECB8D3362F7C" modified="2007-05-15" version="1">MLDEGADWLHVDIMDGHFVPNLTIGPPVVADLAKRVGPRDAFFDCHLSVSNPATLVPALAAAGASSVTFHIEVVSGTAAEELCKTIRSLGMRAAVACKPSTPCDEDGGVYELVDAGLVDMVLCLSVEPGFGGQKFNPAVCDKVSALRARYPDLDIQMDGGVNPSTAELCARAGANVLVAGSAVFGAANPAQVISQLRQSILNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4M7</accession>
    <name>A4S4M7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'-5' exonuclease</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Werner Syndrome-like exonuclease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_93442</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420464.1">
        <property type="nucleotide sequence ID" value="XM_001420427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4M7"/>
    <dbReference type="STRING" id="436017.A4S4M7"/>
    <dbReference type="GeneID" id="5004361"/>
    <dbReference type="Gramene" id="ABO98757">
        <property type="protein sequence ID" value="ABO98757"/>
        <property type="gene ID" value="OSTLU_93442"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93442"/>
    <dbReference type="eggNOG" id="KOG4373">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_601812_0_0_1"/>
    <dbReference type="OMA" id="CGFDMEW"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF109">
        <property type="entry name" value="3'-5' EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="11">
        <location>
            <begin position="10"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="209"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="222"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="389" mass="43667" checksum="84FE4EA1E2557581" modified="2007-05-15" version="1">MDDLTYDGEIVVASTARELEEAMARIEAFDARAGTTATTKHCGFDMEWKVSFKRGAGESKTSLVQIAVANEDLSEKLVVLARIHTAGLTRRFKRWTRDGARGKTGFNVRGDARKLVRDYGLEPSRVIELSVLAKERFEGGCPSAPSWSLARLCEHVLGKTLPKDKTRMSNWEREELNESQIKYAAMDAWASLLVYRALMKRDVVESFGGEPYECDPLPEPVESSDEEVEDEDEDEDEDEDEANAFVDDEEDDEEPTDVVFDDAVDKGELSAQSARAGEIELTDTEREVYAKHIAGASLDDIATTTDTDRIVVFSTLLSAMRKGCAFYFKLLCIPEHLTLFFDDHVMLNGALPKANDFVEYAKIDDERSCKLMLIALTVKLAREREQQQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5B0</accession>
    <name>A4S5B0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_47095</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420742.1">
        <property type="nucleotide sequence ID" value="XM_001420705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5B0"/>
    <dbReference type="STRING" id="436017.A4S5B0"/>
    <dbReference type="GeneID" id="5004841"/>
    <dbReference type="Gramene" id="ABO99035">
        <property type="protein sequence ID" value="ABO99035"/>
        <property type="gene ID" value="OSTLU_47095"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_47095"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="IMHIRAR"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="33"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="234"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="383"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="399"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO99035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="413" mass="44992" checksum="448AC58D15E4CE96" modified="2007-05-15" version="1" fragment="single">MMNFDAGPWPKPLLDAVKRAGYTEPTAIQSQSWPIALQGYDMISVAKTGSGKTVAFLFPGLMHIAERGNGRNARGPMMLALAPTRELATQIQEECMKFGSSCGVGSVCLYGGAPKGRQLQQLRNRPQICIATPGRLNDLLESRMVDMSSATYVVLDEADRMLDMGFEPQIRKILQHVPVDRQTLFFTATWPKAVIRVATAILTNPIQVNIGDTDQLVANKDITQTIEVCSGFEKEKRLMEILNNPPEGCDPLKALVFCSTKRMCDQLGRSVGNLAGIIHGDKEQRERDWILNQFRQGRTPVLVATDVAARGLDVKDCNLVINYDFPNQIEDYVHRIGRTGRAGKKGWAFSFIDGGEGNMARKLIPILRDANQIVSPEIEEMARSAGFGRPKGGRRGGGGRRGGGGGGGYGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S616</accession>
    <name>A4S616_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420864.1">
        <property type="nucleotide sequence ID" value="XM_001420827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S616"/>
    <dbReference type="GeneID" id="5004729"/>
    <dbReference type="Gramene" id="ABO99157">
        <property type="protein sequence ID" value="ABO99157"/>
        <property type="gene ID" value="OSTLU_26956"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26956"/>
    <dbReference type="HOGENOM" id="CLU_1952445_0_0_1"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="129" mass="14535" checksum="36961F29EF27979F" modified="2007-05-15" version="1">MKKLKTLSANQPLASTHKKSQSLVCPHCGFIGKRAAGFANHLRACRRRHEDEPTPTPSPDEAASEQHERREEQQEQEEARARHANTIDILEDTIDILEDTRRLAGDQITLSLPIIVLSPECRMTESPEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S622</accession>
    <name>A4S622_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab3 GTPase-activating protein catalytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_17704</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rab3-GAP catalytic subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420868.1">
        <property type="nucleotide sequence ID" value="XM_001420831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S622"/>
    <dbReference type="STRING" id="436017.A4S622"/>
    <dbReference type="GeneID" id="5004857"/>
    <dbReference type="Gramene" id="ABO99161">
        <property type="protein sequence ID" value="ABO99161"/>
        <property type="gene ID" value="OSTLU_17704"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17704"/>
    <dbReference type="eggNOG" id="KOG2390">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005626_0_0_1"/>
    <dbReference type="OMA" id="RNANDAC"/>
    <dbReference type="OrthoDB" id="568485at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Zhou K."/>
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                <person name="Manuell A."/>
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</entry>
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            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
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            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421163.1">
        <property type="nucleotide sequence ID" value="XM_001421126.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422792.1">
        <property type="nucleotide sequence ID" value="XM_001422755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6W3"/>
    <dbReference type="STRING" id="436017.A4S6W3"/>
    <dbReference type="GeneID" id="5005221"/>
    <dbReference type="GeneID" id="5006850"/>
    <dbReference type="Gramene" id="ABO99456">
        <property type="protein sequence ID" value="ABO99456"/>
        <property type="gene ID" value="OSTLU_27264"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01151">
        <property type="protein sequence ID" value="ABP01151"/>
        <property type="gene ID" value="OSTLU_29647"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27264"/>
    <dbReference type="KEGG" id="olu:OSTLU_29647"/>
    <dbReference type="eggNOG" id="KOG3881">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033769_3_0_1"/>
    <dbReference type="OMA" id="HRKFAAG"/>
    <dbReference type="OrthoDB" id="18388at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037379">
        <property type="entry name" value="WDR74/Nsa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038">
        <property type="entry name" value="NOP SEVEN ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038:SF4">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="292"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="357"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="410" mass="44307" checksum="027513843ACB6F52" modified="2007-05-15" version="1">MAPPHTDLPIRVLACDELGYVRAFATDPAAGGDAAEDLTLIGKFGALDRARRAVRARAVCELRGASDASGPRVVCARKGGAVEVMEARSGTRSTATLTLSKEIVDAHAWCEGDERGTSWERMHVVAVHDDGEVGVHGIVNEYGDETWRETGTFRACGDATSSDLDARLGRLVLGGKGQGNDVVVYDVHEQKRTYKAKPPPPNWLGYRAPPWVSATCFASTSECARFFVGTGEHRFRHYDTRADKRAVLDLDVGKGVITSVASSADGYEAYVANARGMFEIVDLRAGKTRGKFKGNSGSIRQVAVHPDGAHVACAGLDQYVRVYDTATRKCVASAYAKQPLTAIVFDAHTPAFEAASVKKSSKKKKRAPDVDDDDARAEKKAKKKKKKIRECAVAVDDAAPKKKKKKKSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Y7</accession>
    <name>A4S6Y7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_17956</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421176.1">
        <property type="nucleotide sequence ID" value="XM_001421139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6Y7"/>
    <dbReference type="STRING" id="436017.A4S6Y7"/>
    <dbReference type="GeneID" id="5005448"/>
    <dbReference type="Gramene" id="ABO99469">
        <property type="protein sequence ID" value="ABO99469"/>
        <property type="gene ID" value="OSTLU_17956"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17956"/>
    <dbReference type="eggNOG" id="KOG1012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_498200_0_0_1"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45911">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45911:SF4">
        <property type="entry name" value="MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="214"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="391"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="520"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="537"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="547" mass="60422" checksum="5B2233BB688B9D14" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7S8</accession>
    <name>A4S7S8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog</fullName>
            <ecNumber evidence="12">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_27604</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the RPAP2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="12"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421325.1">
        <property type="nucleotide sequence ID" value="XM_001421288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7S8"/>
    <dbReference type="STRING" id="436017.A4S7S8"/>
    <dbReference type="GeneID" id="5005482"/>
    <dbReference type="Gramene" id="ABO99618">
        <property type="protein sequence ID" value="ABO99618"/>
        <property type="gene ID" value="OSTLU_27604"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27604"/>
    <dbReference type="eggNOG" id="KOG4780">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_574144_0_0_1"/>
    <dbReference type="OMA" id="EPPFNEM"/>
    <dbReference type="OrthoDB" id="10492448at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043175">
        <property type="term" value="F:RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039693">
        <property type="entry name" value="Rtr1/RPAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007308">
        <property type="entry name" value="Rtr1/RPAP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038534">
        <property type="entry name" value="Rtr1/RPAP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14732">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14732:SF0">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04181">
        <property type="entry name" value="RPAP2_Rtr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51479">
        <property type="entry name" value="ZF_RTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 12" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RTR1-type" evidence="14">
        <location>
            <begin position="9"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="285"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO99618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="476" mass="52473" checksum="CDEC58AA0D4EE58D" modified="2007-05-15" version="1">MAHEVLERCKQHGMTNKEYQSACAERAACGACGWTPCPNAPTRDDGTTQRYEIDGKARKVREMAFVRAFCSRKCMMMAEALGERLGERADAVSAREGAARGRAAMDGEASVVKQDVRERATTAKKAFDAKMPVRKSDAMAKAATVDGYVPKAARKRIEEEREKEKTHRAASITWNEPEIEKIEEELWREKREASGVDPAGGVFYFDTFGEGKKPEGDFVPSIGGRFSEGQLRTEPRTVVDETSRAMENLLLERNDGEDTESHVALEEDVAETTRRMLASKLTATPIPGFVDDGDDDDDDAMTAGSEEEGEESFTTGAPKISQFGLTWMAVDNLVTDATFALVAGDGAFVDKLPPRDRYTVSVSEAWNENLARTIPNLCVTLNISAETRRVEQNLTTLLRTFAFDRPVPAFTSERWAMMALLFIELLLHADLVSKESIGKEVFDNANAIAVFANAGATSEEVNILRERLRGDGVNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7U1</accession>
    <name>A4S7U1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_89194</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421332.1">
        <property type="nucleotide sequence ID" value="XM_001421295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7U1"/>
    <dbReference type="GeneID" id="5005231"/>
    <dbReference type="Gramene" id="ABO99625">
        <property type="protein sequence ID" value="ABO99625"/>
        <property type="gene ID" value="OSTLU_89194"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89194"/>
    <dbReference type="eggNOG" id="KOG1676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_898313_0_0_1"/>
    <dbReference type="OMA" id="ETIMCPP"/>
    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="272"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="310" mass="32767" checksum="DD59E660ED9CC867" modified="2007-05-15" version="1">MDPSSVTEYVMCPNESAGKVIGHGGEKINSIQTESGAIVKIQNQNEVGPGQPRRITISGAPERVAHASQLVYAIIGQSSASRAAQAPRGAGGGRDAAGAEIFVPVEPDQFGKIIGRGGETIRRLQEESGVRMQVDRPNSRVQITGDASGCEVARTLLQEVLDATNEPVGMGTSGAQSTEISAQGQEGRIIGKGGENIRSLAAQTGAKLSIIKETGMVRIQGDPRQIEDAVRAVNEFIDAQVNPVKYPNAVGGGAGIPSNGAYHPPEDSGGLTPYKPLWETHQSPEGYTYYYNTTTGETTWEEPEDYDGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7V5</accession>
    <name>A4S7V5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_89200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421341.1">
        <property type="nucleotide sequence ID" value="XM_001421304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7V5"/>
    <dbReference type="STRING" id="436017.A4S7V5"/>
    <dbReference type="GeneID" id="5005425"/>
    <dbReference type="Gramene" id="ABO99634">
        <property type="protein sequence ID" value="ABO99634"/>
        <property type="gene ID" value="OSTLU_89200"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89200"/>
    <dbReference type="eggNOG" id="KOG0066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_6_1"/>
    <dbReference type="OMA" id="ARLVLCM"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000549">
        <property type="entry name" value="ABC transporter ATP-binding protein arb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF14">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="101"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="456"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="388"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="396"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="685" mass="76749" checksum="CAB6AC37A862C691" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Z4</accession>
    <name>A4S7Z4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L24, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL24</name>
        <name evidence="5" type="ORF">OSTLU_43138</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421538.1">
        <property type="nucleotide sequence ID" value="XM_001421501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Z4"/>
    <dbReference type="STRING" id="436017.A4S7Z4"/>
    <dbReference type="GeneID" id="5005256"/>
    <dbReference type="Gramene" id="ABO99831">
        <property type="protein sequence ID" value="ABO99831"/>
        <property type="gene ID" value="OSTLU_43138"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43138"/>
    <dbReference type="eggNOG" id="KOG1722">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106411_2_1_1"/>
    <dbReference type="OMA" id="PGHGKKM"/>
    <dbReference type="OrthoDB" id="497981at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL24-related N-terminal" evidence="4">
        <location>
            <begin position="3"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="127" mass="14266" checksum="E275F3085DC7C3F6" modified="2007-05-15" version="1">MVLKTEKCAFSGLRVYPGHGTRLTKIDSTTFLFLNGKSKKMHAQKKKPAKLAWTTTYRKAHKKDIEASTRTKKRRVNKSAFTRSLVGASLEVLAKKRNEKPEVRAAARDAALREIKARAAKKKGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S851</accession>
    <name>A4S851_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Photosystem II reaction center Psb28 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">psbW</name>
        <name evidence="6" type="ORF">OSTLU_40772</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Psb28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421703.1">
        <property type="nucleotide sequence ID" value="XM_001421666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S851"/>
    <dbReference type="STRING" id="436017.A4S851"/>
    <dbReference type="GeneID" id="5005840"/>
    <dbReference type="Gramene" id="ABO99996">
        <property type="protein sequence ID" value="ABO99996"/>
        <property type="gene ID" value="OSTLU_40772"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40772"/>
    <dbReference type="eggNOG" id="ENOG502RMFI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137323_1_0_1"/>
    <dbReference type="OMA" id="LEATYTW"/>
    <dbReference type="OrthoDB" id="1938621at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.220">
        <property type="entry name" value="Photosystem II Psb28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01370">
        <property type="entry name" value="PSII_Psb28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038676">
        <property type="entry name" value="Psb28_c1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005610">
        <property type="entry name" value="PSII_Psb28_class-1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03047">
        <property type="entry name" value="PS_II_psb28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34963">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34963:SF2">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER PSB28 PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03912">
        <property type="entry name" value="Psb28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="129" mass="14346" checksum="517A84545BBA1CF6" modified="2007-05-15" version="1">MNRGVARATRASRAVTRAGTTSIQFVKGQNETSVPEVKLTRSKDGSNGTAFFIFAEPDVFENGQGDITGMFLNDEEGEMSTVDVNAKFINGKPSGIEARYVMKTERDWDRFMRFMARYAEDNGLGFAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8A5</accession>
    <name>A4S8A5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoacetylglucosamine mutase</fullName>
            <ecNumber evidence="5">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_40572</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421732.1">
        <property type="nucleotide sequence ID" value="XM_001421695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8A5"/>
    <dbReference type="STRING" id="436017.A4S8A5"/>
    <dbReference type="GeneID" id="5005627"/>
    <dbReference type="Gramene" id="ABP00026">
        <property type="protein sequence ID" value="ABP00026"/>
        <property type="gene ID" value="OSTLU_40572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40572"/>
    <dbReference type="eggNOG" id="KOG2537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022890_1_0_1"/>
    <dbReference type="OMA" id="WEAYATK"/>
    <dbReference type="OrthoDB" id="1928at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03086">
        <property type="entry name" value="PGM3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016657">
        <property type="entry name" value="PAGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="14">
        <location>
            <begin position="67"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="14">
        <location>
            <begin position="124"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="15">
        <location>
            <begin position="328"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="13">
        <location>
            <begin position="491"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABP00026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="571" mass="60309" checksum="8E2CE4CB72D020B1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8H3</accession>
    <name>A4S8H3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_40532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8H3"/>
    <dbReference type="GeneID" id="5005705"/>
    <dbReference type="Gramene" id="ABP00062">
        <property type="protein sequence ID" value="ABP00062"/>
        <property type="gene ID" value="OSTLU_40532"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40532"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_4_4_1"/>
    <dbReference type="OMA" id="PARAMAC"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF123">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="88"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="459" mass="51549" checksum="77238ABA984A5338" modified="2007-05-15" version="1" fragment="single">MLDIGAYFSKSPTELAGRMAEVLSVIGRVYATWQYEERMGIPLERRTRGKKLRDGIARLGPVFIKMAQTLSTRPDIIGEEAADNLMVLQDQVGPFSTEEAHAIIKRELSWDGAVCERDASKPGPAYSLYKELSPEPIAAASIGQVYAGRLHDGSKVAVKVQRPGMARRIALDLHIIRLGFGWVEESGLNGSEDLDKIVDQVGAGIFQELDYTIEARNADEFRKSLRFLDYLFVPRHHANMTTKKVLTQQWIQGRPMKSLSLEEQKLMVQMGVECSSAQLFRTGLVHADPHEGNMLFTDDGKLALLDFGLICRVDDDQQEAMANCILNILNSQWGELIDNLRIMDMLPQEPQMWIDENGNQADYTQGEGNPKVRANFTELVLDLTKISTAYRFNLPPYMVFVIRSLTTLDFAAARTNCNMYEVAAPTAIFRALSPRTDRGKKALEQMLLDKDGDVNWSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8M3</accession>
    <name>A4S8M3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_93816</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421648.1">
        <property type="nucleotide sequence ID" value="XM_001421611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8M3"/>
    <dbReference type="STRING" id="436017.A4S8M3"/>
    <dbReference type="GeneID" id="5005793"/>
    <dbReference type="Gramene" id="ABO99941">
        <property type="protein sequence ID" value="ABO99941"/>
        <property type="gene ID" value="OSTLU_93816"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93816"/>
    <dbReference type="HOGENOM" id="CLU_461821_0_0_1"/>
    <dbReference type="OMA" id="YEPGCFR"/>
    <dbReference type="OrthoDB" id="1304856at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035825">
        <property type="term" value="P:homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="6">
        <location>
            <begin position="321"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="6">
        <location>
            <begin position="434"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="680" mass="75432" checksum="79D0B6FF91D3BC97" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8N6</accession>
    <name>A4S8N6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421795.1">
        <property type="nucleotide sequence ID" value="XM_001421758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8N6"/>
    <dbReference type="STRING" id="436017.A4S8N6"/>
    <dbReference type="GeneID" id="5005766"/>
    <dbReference type="Gramene" id="ABP00089">
        <property type="protein sequence ID" value="ABP00089"/>
        <property type="gene ID" value="OSTLU_27912"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27912"/>
    <dbReference type="eggNOG" id="ENOG502QRW2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042585_0_1_1"/>
    <dbReference type="OMA" id="WQLVPVY"/>
    <dbReference type="OrthoDB" id="5130at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021883">
        <property type="entry name" value="LPA1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35498:SF1">
        <property type="entry name" value="LOW PSII ACCUMULATION-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35498">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11998">
        <property type="entry name" value="DUF3493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="290" mass="31482" checksum="2A8DA17B5C1FCA83" modified="2007-05-15" version="1">MATAPARSSARPAARPTARRAARRPARRATTTPRRALEDDDARYSNETKLRSEAQAPFRVARQFLYGACAASATIGFGIATIQAATKAAGAPNAPPLEGSLENLAIDGAALATFAWLYAREEAARERQMARIGREERLGRLRVELAGGKTVRLEDLRSFSRVVVVSGDEAYARTALEDAEDVREALIERGVLVVPVIRGDGAIEAPSAEDRKFRCTPLRANDWLEWVAEQKKMSKVSDDKGVYVGLRMDGRVRSSGTGRVPFNRFAVELPPVDSWGGALDGFDGRVGVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Q0</accession>
    <name>A4S8Q0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_40656</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Magnesium transporter that may mediate the influx of magnesium.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421666.1">
        <property type="nucleotide sequence ID" value="XM_001421629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Q0"/>
    <dbReference type="GeneID" id="5005776"/>
    <dbReference type="Gramene" id="ABO99959">
        <property type="protein sequence ID" value="ABO99959"/>
        <property type="gene ID" value="OSTLU_40656"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40656"/>
    <dbReference type="eggNOG" id="KOG2662">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034694_1_0_1"/>
    <dbReference type="OMA" id="GPGRFIW"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF31">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="232"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="405" mass="45504" checksum="CD6CFBF6218D671A" modified="2007-05-15" version="1">MVGKPPRGVGNYDKPNGDDIEPVKAVPVSTSGRAKVGWVRINTLGVVNRLSMEKTKIATLLRVPLRDLRVLEPTTADSYSAAVLCRERAIVVNLEQIKVLITAEEVIMTDSQTSTVTHFLPELQTRFETSPEKELRQAQPTTDEFPFEFVALEVALEMVCNTLEVEANKVELDAKPALEALRKRVDNVNLERVRRMKTRLVRVAGRVSKVREEIQRYLDDDSDMRDMYLTRKSKQQSESLRREGSVTSPPPNGADGGQRGATAHYQLEHALSASSGRSPLGVHGVHTQNKDLQELEDLLETYFTHVDSTHRSLNGLNEYIDDLEDLIEIELDSQRNQLIKLELILTTATLCLTCFSVVVGIFGMNIKNNVENEHGMFLLVVLLGSAATIGMFIILLRVCRYYRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S914</accession>
    <name>A4S914_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_18495</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFB1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421986.1">
        <property type="nucleotide sequence ID" value="XM_001421949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S914"/>
    <dbReference type="STRING" id="436017.A4S914"/>
    <dbReference type="GeneID" id="5006026"/>
    <dbReference type="Gramene" id="ABP00280">
        <property type="protein sequence ID" value="ABP00280"/>
        <property type="gene ID" value="OSTLU_18495"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18495"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Tfb1/GTF2H1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013876">
        <property type="entry name" value="TFIIH_BTF_p62_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12856">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
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        <location>
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            <end position="242"/>
        </location>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="585" mass="64543" checksum="1F9515111D961B54" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9N3</accession>
    <name>A4S9N3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Gramene" id="ABP00414">
        <property type="protein sequence ID" value="ABP00414"/>
        <property type="gene ID" value="OSTLU_28260"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="647" mass="72804" checksum="D5810726AE49AE08" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA47</accession>
    <name>A4SA47_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-glucose/GDP-mannose dehydrogenase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422284.1">
        <property type="nucleotide sequence ID" value="XM_001422247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA47"/>
    <dbReference type="STRING" id="436017.A4SA47"/>
    <dbReference type="GeneID" id="5006364"/>
    <dbReference type="Gramene" id="ABP00601">
        <property type="protein sequence ID" value="ABP00601"/>
        <property type="gene ID" value="OSTLU_93979"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93979"/>
    <dbReference type="HOGENOM" id="CLU_1954374_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43750:SF2">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43750">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE TUAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase N-terminal" evidence="1">
        <location>
            <begin position="32"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="129" mass="14431" checksum="068128FC579821CD" modified="2007-05-15" version="1" fragment="single">VILGQSPSLTLQRRRAKMATTRSILQTTRARFVGLGRLGLCTALKCEQADWDIVGSDVFPAHVDSINEITLRLTEPRVEEALRSSKHLRATLKLREVIDRVDMVFILVATPTDSGDQAYDTSALSRFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA54</accession>
    <name>A4SA54_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DMT family transporter: GDP-mannose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_18795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422319.1">
        <property type="nucleotide sequence ID" value="XM_001422282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA54"/>
    <dbReference type="STRING" id="436017.A4SA54"/>
    <dbReference type="GeneID" id="5006342"/>
    <dbReference type="Gramene" id="ABP00636">
        <property type="protein sequence ID" value="ABP00636"/>
        <property type="gene ID" value="OSTLU_18795"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18795"/>
    <dbReference type="eggNOG" id="KOG1444">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_925558_0_0_1"/>
    <dbReference type="OMA" id="WMGINIV"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="301" mass="32469" checksum="E807A197A8BD5AED" modified="2007-05-15" version="1">MAVVTITLVAAAFCLSGSALTVLNKQIMGFFPAPNAVLFAQNAVTLVLLAFGKSVLSLQIEPVRRHKAKRWFALVLLFYAMLASSMLALKFVTATTLIVQRNLGTVTIAIADYFCLGTVQTKPRILAILGMCAGSLVYASGDLDAASNFDFTGYAWLAVNVAATTAYQIKVKSLVNELDMNSWTMAYYNNLLSLPVCAIVGFAQRENETLQKFMASGATKSQCVALFVSCTLGFCLSVSAFQLNRLITPTSITILNNTNKFALIFFTAYFMDYSTLSESTVAGAAIVMICAAHYSFAGTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAG4</accession>
    <name>A4SAG4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422431.1">
        <property type="nucleotide sequence ID" value="XM_001422394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAG4"/>
    <dbReference type="GeneID" id="5006440"/>
    <dbReference type="Gramene" id="ABP00748">
        <property type="protein sequence ID" value="ABP00748"/>
        <property type="gene ID" value="OSTLU_18874"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18874"/>
    <dbReference type="HOGENOM" id="CLU_369447_0_0_1"/>
    <dbReference type="OrthoDB" id="10648648at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="650"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="688"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="740"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="754" mass="80927" checksum="2C39428B147065AA" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAI7</accession>
    <name>A4SAI7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AP-3 complex subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_42302</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422394.1">
        <property type="nucleotide sequence ID" value="XM_001422357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAI7"/>
    <dbReference type="STRING" id="436017.A4SAI7"/>
    <dbReference type="GeneID" id="5006499"/>
    <dbReference type="Gramene" id="ABP00711">
        <property type="protein sequence ID" value="ABP00711"/>
        <property type="gene ID" value="OSTLU_42302"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42302"/>
    <dbReference type="eggNOG" id="KOG1059">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001908_1_0_1"/>
    <dbReference type="OMA" id="HVECSAT"/>
    <dbReference type="OrthoDB" id="10264595at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000251">
        <property type="entry name" value="AP-3 complex subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017105">
        <property type="entry name" value="AP3_complex_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781:SF12">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781">
        <property type="entry name" value="DELTA ADAPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037092">
        <property type="entry name" value="AP3_complex_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="40"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="622" mass="68938" checksum="0AEB2A04AFBD8CEE" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAK9</accession>
    <name>A4SAK9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Suppressor of forked domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_42299</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422408.1">
        <property type="nucleotide sequence ID" value="XM_001422371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAK9"/>
    <dbReference type="STRING" id="436017.A4SAK9"/>
    <dbReference type="GeneID" id="5006466"/>
    <dbReference type="Gramene" id="ABP00725">
        <property type="protein sequence ID" value="ABP00725"/>
        <property type="gene ID" value="OSTLU_42299"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42299"/>
    <dbReference type="eggNOG" id="KOG2047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007736_0_0_1"/>
    <dbReference type="OMA" id="PDKIKFY"/>
    <dbReference type="OrthoDB" id="10067343at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000023">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000137">
        <property type="entry name" value="Pre-mRNA-splicing factor syf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056350">
        <property type="entry name" value="HAT_Syf1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23220">
        <property type="entry name" value="HAT_Syf1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="11">
        <location>
            <begin position="20"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor SYF1 central HAT repeats" evidence="9">
        <location>
            <begin position="191"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="10">
        <location>
            <begin position="404"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="873" mass="99266" checksum="4A9324C4E7EFAF4F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAM6</accession>
    <name>A4SAM6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_43627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422459.1">
        <property type="nucleotide sequence ID" value="XM_001422422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAM6"/>
    <dbReference type="STRING" id="436017.A4SAM6"/>
    <dbReference type="GeneID" id="5006694"/>
    <dbReference type="Gramene" id="ABP00776">
        <property type="protein sequence ID" value="ABP00776"/>
        <property type="gene ID" value="OSTLU_43627"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43627"/>
    <dbReference type="eggNOG" id="ENOG502QSCQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_3_1_1"/>
    <dbReference type="OrthoDB" id="10039976at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004059">
        <property type="term" value="F:aralkylamine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004468">
        <property type="term" value="F:L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030187">
        <property type="term" value="P:melatonin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010187">
        <property type="term" value="P:negative regulation of seed germination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062055">
        <property type="term" value="P:photosynthetic state transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031537">
        <property type="term" value="P:regulation of anthocyanin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000904">
        <property type="term" value="P:regulation of starch metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090333">
        <property type="term" value="P:regulation of stomatal closure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009644">
        <property type="term" value="P:response to high light intensity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904880">
        <property type="term" value="P:response to hydrogen sulfide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010555">
        <property type="term" value="P:response to mannitol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006970">
        <property type="term" value="P:response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042428">
        <property type="term" value="P:serotonin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046739">
        <property type="term" value="P:transport of virus in multicellular host"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045039">
        <property type="entry name" value="NSI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626:SF4">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="163" mass="17848" checksum="748C460AE3176119" modified="2007-05-15" version="1" fragment="single">VDITLQTTTTENGAVKAMVFSTTAPVDVLEVERLCACAGWPDRPRAKLKRALENSFMVATLYECDVDASTGNVGETSRGRLVGCARATSDHVFNSTLWDIIVDPEYQGKGLGKALVQQMIRSLLARDVANVTLFADQDVIPFYRALGFVQDPEGIKGMFLYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAS4</accession>
    <name>A4SAS4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_43750</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Protein modification.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422486.1">
        <property type="nucleotide sequence ID" value="XM_001422449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAS4"/>
    <dbReference type="STRING" id="436017.A4SAS4"/>
    <dbReference type="GeneID" id="5006544"/>
    <dbReference type="Gramene" id="ABP00803">
        <property type="protein sequence ID" value="ABP00803"/>
        <property type="gene ID" value="OSTLU_43750"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43750"/>
    <dbReference type="eggNOG" id="KOG0417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_3_1"/>
    <dbReference type="OMA" id="NQMAREW"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000001">
        <property type="entry name" value="Ubiquitin-conjugating enzyme 28, E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="149" mass="16870" checksum="FA2002FCE64B6429" modified="2007-05-15" version="1">MASKRIIKELLDLQKDPPTSCSAGPRSDDDIFHWDATIIGPSDSPYQGGLFFVAIHFPPDYPFKPPKVNFKTKVYHPNVNSQGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLVPEIAHIYKTDRNRYNDLAKEWTRKYATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAU1</accession>
    <name>A4SAU1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422498.1">
        <property type="nucleotide sequence ID" value="XM_001422461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAU1"/>
    <dbReference type="STRING" id="436017.A4SAU1"/>
    <dbReference type="GeneID" id="5006556"/>
    <dbReference type="Gramene" id="ABP00815">
        <property type="protein sequence ID" value="ABP00815"/>
        <property type="gene ID" value="OSTLU_29379"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29379"/>
    <dbReference type="eggNOG" id="ENOG502QR94">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081102_0_0_1"/>
    <dbReference type="OMA" id="NEIGQMI"/>
    <dbReference type="OrthoDB" id="2019800at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47869">
        <property type="entry name" value="OS03G0410700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47869:SF2">
        <property type="entry name" value="OS03G0410700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="130"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="262" mass="27439" checksum="00807A7AB06D3073" modified="2007-05-15" version="1">MLDVMEGGPKLRRWYGSDSSVGDGTGASGDENGDETAAYGDADEADEDDDDVELNLPKTSILVTNADGALGESIVVQLILAKASVVAACEAEQIVGAETRFGPYVNVVSNSMSAGARLNGVRAMVVTDALEEDLLAACVRRGVKHVVLVSSAKSAGGGLFPSANEKARRDKTREELAKRSGVALTIIRPCSVKSSPSQGREIRFGQGDTLTGEVSMEDLAEVCARALTRPPKPGESLEFEVSNGAAAAERDWKALFAPLVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB39</accession>
    <name>A4SB39_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422548.1">
        <property type="nucleotide sequence ID" value="XM_001422511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB39"/>
    <dbReference type="GeneID" id="5006768"/>
    <dbReference type="Gramene" id="ABP00865">
        <property type="protein sequence ID" value="ABP00865"/>
        <property type="gene ID" value="OSTLU_29476"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29476"/>
    <dbReference type="HOGENOM" id="CLU_533621_0_0_1"/>
    <dbReference type="OMA" id="NCERALG"/>
    <dbReference type="OrthoDB" id="496441at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="511" mass="56062" checksum="0FD5F3BCEA576C0A" modified="2007-05-15" version="1">MESLARAVMTSIPPNAIDRQRVCEVIGRAEGARASGRHRDAAKMLIDVGGALTRLQHETAVAVAEQAFQCAVQQARLNDEDVPEYMKNATEGSNAELGEAYASLGNCERALGKLADAEGHYKAAVKAVEDDGLEPFSNKFVLRVMVTRVRKDFQKHEQLCDAWEETIRKAAREGTESQTALLAATGICLQERAGGMAEQKKFNEAAELRGGKFLETVLRLQAHGLRTKPDVLLPNVYDSIAALYLQAKDIKKALGFLHRAVASTACTECYGDKFIPEGETRGIKAEGKWDDVCWHPSLLASKKGVEQDEVDVVPRAPWEVSPEEKKIIDQILGVGDKWTMKKGKEGPEPARGANALGHILYTLGNHLMQAAKWEEAGRPLKTAAAMLQNDLDMQGNCFHLLGVVHFQIAKLPMNRARVKEILPRAASSFALAADCRIVDGKCTKKGAAESINSLLFLGRCMFELGEFEQTEQVTAQAISLGRQVLGDNAKETNEAIKAMMEFKRQMSMMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB76</accession>
    <name>A4SB76_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transglutaminase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_5312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglutaminase-like superfamily. PNGase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422727.1">
        <property type="nucleotide sequence ID" value="XM_001422690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB76"/>
    <dbReference type="STRING" id="436017.A4SB76"/>
    <dbReference type="GeneID" id="5006627"/>
    <dbReference type="Gramene" id="ABP01044">
        <property type="protein sequence ID" value="ABP01044"/>
        <property type="gene ID" value="OSTLU_5312"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5312"/>
    <dbReference type="eggNOG" id="KOG0909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031058_0_0_1"/>
    <dbReference type="OMA" id="PRYNSAI"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
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                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
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                <person name="Napoli C."/>
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                <person name="Tai V."/>
                <person name="Vallon O."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
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        <source>
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        <source>
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</entry>
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            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Zhou K."/>
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                <person name="Podell S."/>
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                <person name="Napoli C."/>
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                <person name="Manuell A."/>
                <person name="Tai V."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
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                <person name="Schmutz J."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </feature>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="127" mass="13138" checksum="30637F8189EF024B" modified="2007-05-15" version="1">MPERNPGLAYMMHVPGGCMEDTGDCCYASCCPACHMGSIADRTNTGSFCMTAAIASCLGPFSPLYLKCVASKALESVGVKPVGYVESCSMPSCVACQVSREINERKQMGGKTGGAPTAAPTAQTVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR45</accession>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <end position="392"/>
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</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="gene ID" value="OSTLU_28900"/>
    </dbReference>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
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    </dbReference>
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        <location>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRB6</accession>
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        <recommendedName>
            <fullName evidence="2">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
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                <person name="Schmutz J."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="436017.A4RRB6"/>
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        <property type="gene ID" value="OSTLU_13808"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13808"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_238540_0_0_1"/>
    <dbReference type="OMA" id="KINAVSC"/>
    <dbReference type="OrthoDB" id="533095at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="1032"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
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            <end position="1141"/>
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    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
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            <end position="1664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1675" mass="175001" checksum="4396E40E0AAF015C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRK9</accession>
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        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">OSTLU_29054</name>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
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                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
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        <property type="gene ID" value="OSTLU_29054"/>
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    <dbReference type="KEGG" id="olu:OSTLU_29054"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
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    <dbReference type="SUPFAM" id="SSF52821">
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    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="13"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="100" mass="10747" checksum="C0BC80792E098DE5" modified="2007-05-15" version="1">MDGADADDADGSKDAKSMVMDDVGGCRAVRAKEILEASGFKRVVIVRGGANAWKSAWDSNTRRRQLPGSFSRGFDNPMFADSNVVAEEFGASSDDTVWIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRP1</accession>
    <name>A4RRP1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_29087</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415935.1">
        <property type="nucleotide sequence ID" value="XM_001415898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRP1"/>
    <dbReference type="STRING" id="436017.A4RRP1"/>
    <dbReference type="GeneID" id="4999560"/>
    <dbReference type="Gramene" id="ABO94227">
        <property type="protein sequence ID" value="ABO94227"/>
        <property type="gene ID" value="OSTLU_29087"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29087"/>
    <dbReference type="eggNOG" id="KOG2750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_569113_0_0_1"/>
    <dbReference type="OMA" id="CGPKNAG"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051731">
        <property type="term" value="F:polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000448">
        <property type="term" value="P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057570">
        <property type="entry name" value="NOL9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25467">
        <property type="entry name" value="NOL9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 P-loop" evidence="10">
        <location>
            <begin position="74"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="NOL9 C-terminal" evidence="11">
        <location>
            <begin position="346"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="261"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="480" mass="50740" checksum="A987E3DEFAC8048F" modified="2007-05-15" version="1">MASATTCAASGGGGATLEFRAVRGGGAYAVCGAREARALGWTPTMVSRDWERALTRVREAATRTREAFAAAFVGPKGVGKSTLARHAANVILRERGVCGWLDLDCGQPELTAPGMVSLTILRAPLLGPPQTHQASGAEFEGAPSAPLYASFVGDVSPQGDPDAYVEGALACVDAWAALGEDKPALVVNASGWVKGLGLELAEEILRAVGRSTESCYVININSHVASRNVPDDVYWFHDANVPETSNPRVTTYEVAAGFGTAPKGADAETEETSVETYENIANDASPGGTKSKDTKRSPSDSRALSWLAWSRQTVAMCNERPHEGALELDDLGENEAFAATAFDLTTATPWRVSFDDITLHVLQSDLDAREALMALNGAVVGLLKSAAPGRYCAECVGVGVVRGIDVDNRYVYILTPVSSEKLKSVTTLALGTLEFPPRLLGHAGEYPYMQVGAIANEGSGSKAIKSRNNILRQNTAPTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRP8</accession>
    <name>A4RRP8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_86229</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415938.1">
        <property type="nucleotide sequence ID" value="XM_001415901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRP8"/>
    <dbReference type="STRING" id="436017.A4RRP8"/>
    <dbReference type="CAZy" id="CBM1">
        <property type="family name" value="Carbohydrate-Binding Module Family 1"/>
    </dbReference>
    <dbReference type="GeneID" id="4999586"/>
    <dbReference type="Gramene" id="ABO94230">
        <property type="protein sequence ID" value="ABO94230"/>
        <property type="gene ID" value="OSTLU_86229"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86229"/>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_549076_0_0_1"/>
    <dbReference type="OMA" id="IFQKAHR"/>
    <dbReference type="OrthoDB" id="496647at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47988">
        <property type="entry name" value="SOMATIC EMBRYOGENESIS RECEPTOR KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="418"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="455"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="497" mass="53642" checksum="91C1D55B66B7666A" modified="2007-05-15" version="1">MATRATDAGDAEAVRTLLASARDDEALGRALAIGDVCAIGDGTVACDENGRVVKIRLRGRGLRGRLPARVPRMERLTTLDASDNALEGTISEEFLLAMPNLVELHLNLNTLEGPIPKSIGTLTSLEVLNLDGGFTERQRRFDASVPVDKREVYGFPGVHFGNQLSGSVPAEIGNLVKLRELNLHRNMLGLKTDRLALPASVGNLVELESMDVSGNQLHGAIPQELATLPRLRTLNLDDNFISGFIPSDWSSALALESLIVEGNFLSGTLPRFLPRNLTFLDVHENLLTGSINELSRLKRLEGVLLDRCRFTGPVTLSKASLPNLKMISLANNAGLCGALPDLPFATKEQKEAECDKPWELCQLWPETAGTLLGLGSCQCAAPGEGCSIWELSGRKETCCEEGTCLSVPFEFGGKQCVPCSDAYQKCGGKSFDGPTCCKRGLTCTRIDDDRSECLPCNAQWEQCAGALYDGPKCCAPGNSCVYFDAYYSQCQPSSVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRW1</accession>
    <name>A4RRW1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial ClpX chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ClpX1</name>
        <name evidence="6" type="ORF">OSTLU_23955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">CCE9901</strain>
        </source>
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    <dbReference type="Gramene" id="ABO93929">
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        <property type="gene ID" value="OSTLU_23955"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_23955"/>
    <dbReference type="eggNOG" id="KOG0745">
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    </dbReference>
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    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit ClpX"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01086"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="74" mass="7554" checksum="A5956FE9C696CABA" modified="2007-05-15" version="1">MFSMFTGGTAAPSGVSQPSTAANANASRGAAAETFVEALRSQPDPATVTAKTKPKLSFAALMANDEPESFEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSB0</accession>
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            <taxon>Mamiellophyceae</taxon>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ABO94573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A4RSB0"/>
    <dbReference type="STRING" id="436017.A4RSB0"/>
    <dbReference type="GeneID" id="5000369"/>
    <dbReference type="Gramene" id="ABO94573">
        <property type="protein sequence ID" value="ABO94573"/>
        <property type="gene ID" value="OSTLU_30316"/>
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    <dbReference type="KEGG" id="olu:OSTLU_30316"/>
    <dbReference type="eggNOG" id="KOG1963">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005417_3_0_1"/>
    <dbReference type="OMA" id="MPIASGD"/>
    <dbReference type="OrthoDB" id="498846at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057644">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="WD repeat-containing protein 75 second beta-propeller" evidence="8">
        <location>
            <begin position="339"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="816" mass="86999" checksum="871ABBF8E75CFF15" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSC0</accession>
    <name>A4RSC0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII28-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_30305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416275.1">
        <property type="nucleotide sequence ID" value="XM_001416238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSC0"/>
    <dbReference type="STRING" id="436017.A4RSC0"/>
    <dbReference type="GeneID" id="5000222"/>
    <dbReference type="Gramene" id="ABO94568">
        <property type="protein sequence ID" value="ABO94568"/>
        <property type="gene ID" value="OSTLU_30305"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30305"/>
    <dbReference type="eggNOG" id="KOG3219">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088696_2_2_1"/>
    <dbReference type="OMA" id="LNQACNP"/>
    <dbReference type="OrthoDB" id="28335at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08048">
        <property type="entry name" value="HFD_TAF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="7">
        <location>
            <begin position="32"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="140" mass="16141" checksum="6BDA11C6B4BBD9C6" modified="2007-05-15" version="1">MVDGEDLDHRRRDDDASIEAQRDADRARMLELLKTFTPSQMERYECFRRSNLSKTMLRRLFKAASGVTLNANGLIILAGVSKMFVGEMVETAREIMKSRGMNEYEEIRPEHLREAAAVIDAKDGLLRRKRQKSLFTRGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSJ6</accession>
    <name>A4RSJ6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Probable complex I intermediate-associated protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Cia30</name>
        <name evidence="7" type="ORF">OSTLU_119688</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CIA30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416235.1">
        <property type="nucleotide sequence ID" value="XM_001416198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSJ6"/>
    <dbReference type="STRING" id="436017.A4RSJ6"/>
    <dbReference type="GeneID" id="5000279"/>
    <dbReference type="Gramene" id="ABO94528">
        <property type="protein sequence ID" value="ABO94528"/>
        <property type="gene ID" value="OSTLU_119688"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119688"/>
    <dbReference type="eggNOG" id="KOG2435">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_685854_0_0_1"/>
    <dbReference type="OrthoDB" id="42561at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF18">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="6">
        <location>
            <begin position="136"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="69"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="402" mass="43663" checksum="32EC55E962488CBA" modified="2007-05-15" version="1">MARARSSALRRVRSRVERRSRARARRGVRRRARAGRAALSAARRFIGAARAARRRMALRRASKVATAVSRARAASAAHRGARATREGTSRASRAGGVDAASSSTRRAGAPTRALASASAPWYAASPSGRAVTLLCAFASATDRGRWDVFGDFEHGGASACELVAGRDDDEDSDDAGEDNGGATMERMDDARREALRRRYSTLRGRVDCAPPPSGTKSRLKRSGFAGARTKPLTRTLVNPDPTLDFDAYDALSYRVRGDGRMYVASVRTENWMTGDSAEDVWQAAFRPPKDEWVDVVVPIEAFVQTHRGRAVRDHSRMSANRVVFLGLAVAGSAEKSLEARRAEADGPFRLDVHSISGLRMTEEELEAHAAAREGTRENYPCGGFAARAVEALDARDDFVNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP3</accession>
    <name>A4RSP3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CycK-related cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CycK</name>
        <name evidence="3" type="ORF">OSTLU_119632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416457.1">
        <property type="nucleotide sequence ID" value="XM_001416420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP3"/>
    <dbReference type="STRING" id="436017.A4RSP3"/>
    <dbReference type="GeneID" id="5000249"/>
    <dbReference type="Gramene" id="ABO94750">
        <property type="protein sequence ID" value="ABO94750"/>
        <property type="gene ID" value="OSTLU_119632"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119632"/>
    <dbReference type="eggNOG" id="KOG0834">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022000_4_1_1"/>
    <dbReference type="OMA" id="MYDMMKY"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21797">
        <property type="entry name" value="CycT2-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036580">
        <property type="entry name" value="Cyclin_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="21"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="142"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="245" mass="27896" checksum="E760126D6196A863" modified="2007-05-15" version="1">MSSSIRTAKDASTERRWRYCDFLKEAGMKLKVPQLTIATAAVFCHRFFELDSQNAQQFETAVMATACLFLAGKVEETPKPLNDLARTSHLLQRKASDPTRLESSQQELHVELKETILRAERVLLHRLGFDFNVEHPYKHLLSVIKRMSQAGLIEEESTKTLAQVSWNFANDSLRTSLCLEYSANHIAEAVVYLATKFLSSKFELPKKWWEAVNVDPEISELIGNRILDLYEQTGPVELGYSDIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT20</accession>
    <name>A4RT20_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PSII 6.1 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PsbW</name>
        <name evidence="11" type="ORF">OSTLU_119497</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the psbW family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416389.1">
        <property type="nucleotide sequence ID" value="XM_001416352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT20"/>
    <dbReference type="STRING" id="436017.A4RT20"/>
    <dbReference type="GeneID" id="5000483"/>
    <dbReference type="Gramene" id="ABO94682">
        <property type="protein sequence ID" value="ABO94682"/>
        <property type="gene ID" value="OSTLU_119497"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119497"/>
    <dbReference type="eggNOG" id="ENOG502SDRE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1638194_0_0_1"/>
    <dbReference type="OrthoDB" id="2017665at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009806">
        <property type="entry name" value="PSII_PsbW_class2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34552">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER W PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34552:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER W PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07123">
        <property type="entry name" value="PsbW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="162" mass="17210" checksum="A5621FDD77ABC508" modified="2007-05-15" version="1">MFTISSVISTPCNVVQRRSGTCALSAKRYDRVVKRAITRTDKSFSHRQSRSKMPLPSDQVRRKISICIRLVTMSATAPQEMGKRVAGSFALSSMVNVLPALAIVDDRLNGDGTGLPLGINDGALGIILATVPLAIFGLYFIAGKQDASIVAGGKDDDSGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="107" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT29</accession>
    <name>A4RT29_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="7">3.4.21.92</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ClpP5</name>
        <name evidence="10" type="ORF">OSTLU_30030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="7"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416147.1">
        <property type="nucleotide sequence ID" value="XM_001416110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT29"/>
    <dbReference type="STRING" id="436017.A4RT29"/>
    <dbReference type="MEROPS" id="S14.A01"/>
    <dbReference type="GeneID" id="5000423"/>
    <dbReference type="Gramene" id="ABO94440">
        <property type="protein sequence ID" value="ABO94440"/>
        <property type="gene ID" value="OSTLU_30030"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30030"/>
    <dbReference type="eggNOG" id="KOG0840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_0_1"/>
    <dbReference type="OMA" id="EIMHHKS"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009534">
        <property type="term" value="C:chloroplast thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009840">
        <property type="term" value="C:chloroplastic endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000014">
        <property type="entry name" value="ATP-dependent Clp protease proteolytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001368">
        <property type="entry name" value="PRK00277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009205">
        <property type="entry name" value="PRK12553.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF12">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="251" mass="27074" checksum="A7288E46780D060A" modified="2007-05-15" version="1">MQARSLYRFKTQHSSGVGSSSARIDRSKHQGLQTRVKAGLYVSNQQGKGPSPIVLERFQSVASQLMSQRIIRLGGAVDDDSCNLIVAQLLWLDAADPTKDITLYVNSPGGSVTAGMAVFDTMRHIRPNVSTVCVGLAASMGAFLLASGHPGKRYSLPNSRIMIHQPLGGAQGQAADIEIQANEIMHHKSTLNGYLAEFTKKPLETVMEDTDRDFFMSAKEAVEYGLIDAIIEHPTDVAVKASGIPMYASGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU04</accession>
    <name>A4RU04_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416876.1">
        <property type="nucleotide sequence ID" value="XM_001416839.1"/>
    </dbReference>
    <dbReference type="GeneID" id="5000844"/>
    <dbReference type="Gramene" id="ABO95169">
        <property type="protein sequence ID" value="ABO95169"/>
        <property type="gene ID" value="OSTLU_24186"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24186"/>
    <dbReference type="HOGENOM" id="CLU_247026_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd22758">
        <property type="entry name" value="OTU_232R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="33"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1536" mass="170798" checksum="B787C5996DB4B52D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUK4</accession>
    <name>A4RUK4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine transaminase</fullName>
            <ecNumber evidence="4">2.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_12357</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-(phosphooxy)-L-threonine + 2-oxoglutarate = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-serine + 2-oxoglutarate = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="4"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416687.1">
        <property type="nucleotide sequence ID" value="XM_001416650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUK4"/>
    <dbReference type="STRING" id="436017.A4RUK4"/>
    <dbReference type="GeneID" id="5000836"/>
    <dbReference type="Gramene" id="ABO94980">
        <property type="protein sequence ID" value="ABO94980"/>
        <property type="gene ID" value="OSTLU_12357"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12357"/>
    <dbReference type="eggNOG" id="KOG2790">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034866_0_2_1"/>
    <dbReference type="OMA" id="AFVYFCD"/>
    <dbReference type="OrthoDB" id="1703350at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00611">
        <property type="entry name" value="PSAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000010">
        <property type="entry name" value="Phosphoserine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000006">
        <property type="entry name" value="Phosphoserine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003764">
        <property type="entry name" value="PRK05355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01364">
        <property type="entry name" value="serC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247:SF1">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="13">
        <location>
            <begin position="36"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="394" mass="42735" checksum="C63B1E84EB1E2914" modified="2007-05-15" version="1">MRFLNRPRDDAGANETRGGRAVARAGARPGAGNRLYNFSAGPATLPLDVLEEIQRDLVDYKGSGMSVLEMSHRGKDYMAIAEKAEKDLRELVGIPDNYKVLFLQGGASTMMASNCHNLAAATDSADFVVTGAWSVKAQKEGAKMLAKANVIASSKDQSFTTIPDVKDWKFTEGSKFVHICSNETIGGVEFKEVPDVGNRVLVADMSSNYLSKPIEVEKYGIIYGGVQKNIGPAGMGIAIVREDLMGNTRADTPSMFDYKLMADNDSMYNTPPCFTWYVSGLVFAKLLKDGGLKAMEQRNIEKANVLYGAIDGSGGYYVSPVDTKYRSLMNVPFTLAGGEELEKKFLAEAKAEGFEALKGHRSVGGARASIYNAMPKEGVEALVSFMKDFQARNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUR8</accession>
    <name>A4RUR8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_12370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416718.1">
        <property type="nucleotide sequence ID" value="XM_001416681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUR8"/>
    <dbReference type="STRING" id="436017.A4RUR8"/>
    <dbReference type="GeneID" id="5001073"/>
    <dbReference type="Gramene" id="ABO95011">
        <property type="protein sequence ID" value="ABO95011"/>
        <property type="gene ID" value="OSTLU_12370"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12370"/>
    <dbReference type="eggNOG" id="KOG2130">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016785_1_0_1"/>
    <dbReference type="OMA" id="NGWWHAV"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032452">
        <property type="term" value="F:histone demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010476">
        <property type="term" value="P:gibberellin mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010030">
        <property type="term" value="P:positive regulation of seed germination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010099">
        <property type="term" value="P:regulation of photomorphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010114">
        <property type="term" value="P:response to red light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.650:FF:000045">
        <property type="entry name" value="F-box protein At1g78280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF21">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="7">
        <location>
            <begin position="80"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="34215" checksum="BCEE10268A01D881" modified="2007-05-15" version="1">MSVDEFREKYESLNIPVVIRGAAKNWPAMKKWTRQALVRKFGAIDFTVGGYEMALKDFFACSDGCSDDTPLYLFDPLFGEKAPELANDYTVPEYFARDDLFKLLSDDRPHYRWLIVGPSKSGSIFHKDPNATSAWNACITGRKRWIMFKPNQNPPGVYPSADGAEVAQPHSLVEWFTSFYEFANKEGALECVCEPGDVLFVPSGWWHMALNLTECIAITQNYVSVANLPKVLDFLDTKCENLVSGLDKNRRGGLSDRFVAALRASGDDALLAIVDAHARKKTSATQKAKSIIGDAFATASASSFSFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV16</accession>
    <name>A4RV16_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_33886</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417059.1">
        <property type="nucleotide sequence ID" value="XM_001417022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV16"/>
    <dbReference type="STRING" id="436017.A4RV16"/>
    <dbReference type="GeneID" id="5001096"/>
    <dbReference type="Gramene" id="ABO95352">
        <property type="protein sequence ID" value="ABO95352"/>
        <property type="gene ID" value="OSTLU_33886"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33886"/>
    <dbReference type="eggNOG" id="KOG1691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066963_3_1_1"/>
    <dbReference type="OMA" id="MAIRGIF"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="20480" checksum="E31BA92C39B50815" modified="2007-05-15" version="1">MKCVSEDIHANAVVLFAFETVMEGDEVSVKVFDAKGKVAWEKNDATSGRHGFTSETEGEHRACFYKPELTSLGDEKAKAAALAKHRVRVDWKHGVAATEWKSLAKATDLDAFTRTLRALEADLREVHDGMLNLRALEAEMRDMNESTNAKVAWLSVLSLSVCVGMCVWQIVYLKGFFERKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV18</accession>
    <name>A4RV18_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphatidylinositol N-acetylglucosaminyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_49124</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417060.1">
        <property type="nucleotide sequence ID" value="XM_001417023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV18"/>
    <dbReference type="STRING" id="436017.A4RV18"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="GeneID" id="5000736"/>
    <dbReference type="Gramene" id="ABO95353">
        <property type="protein sequence ID" value="ABO95353"/>
        <property type="gene ID" value="OSTLU_49124"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49124"/>
    <dbReference type="eggNOG" id="KOG1111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_19_0_1"/>
    <dbReference type="OMA" id="SHFWMSG"/>
    <dbReference type="OrthoDB" id="734129at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="3">
        <location>
            <begin position="36"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="2">
        <location>
            <begin position="190"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="49698" checksum="70CAA9F2F7DCD98A" modified="2007-05-15" version="1">MLSDFFLPSIGGVELHIYALAARLRARGHKVVVYTHAHPGRVGVRWITRGIKVYHVPRVVMYDNCTFPNFLGGFKLFRKTCVREGVTLVHAHQGCTMSHEGILYARTMGMKCVFTDHSLFGFADVGAIHTNKLLDMTLADTQHAICVSHTAKENTVLRSGYLLGGEPGLAPERVSVIPNAVDSVRFTPDVTKRKKGRRTVVVTSRLMYRKGVHLLAGVIPLACAEHDDLDFLIAGDGSMRKHLEKAIEDAGLTERVTILGSVSHDKVPEVLRRGDVFLNASLTESFCIAVLEAASCGCLVVATAVGGVPEVLPEDIMFLAKPDVQSILDALDECLEALPRADPWRIHERVEALYNWDDVAHRVELAYDRAYDTWDTFMGRLYRLYRRGVVFGKMLWCVAAVTYLWWRALEFFEPAASIEPALALDDERFDVERFDDERALAREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV26</accession>
    <name>A4RV26_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_33818</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417064.1">
        <property type="nucleotide sequence ID" value="XM_001417027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV26"/>
    <dbReference type="STRING" id="436017.A4RV26"/>
    <dbReference type="GeneID" id="5001014"/>
    <dbReference type="Gramene" id="ABO95357">
        <property type="protein sequence ID" value="ABO95357"/>
        <property type="gene ID" value="OSTLU_33818"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33818"/>
    <dbReference type="eggNOG" id="KOG0297">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006994_2_0_1"/>
    <dbReference type="OMA" id="CCARDRY"/>
    <dbReference type="OrthoDB" id="273771at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042755">
        <property type="entry name" value="COP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44080">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44080:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="24"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="402" mass="43387" checksum="2D0BDBC271C78154" modified="2007-05-15" version="1" fragment="single">MSALTLPRGAHARATSAMLAHVTCPICLEPFTDAHCVATCGHTFCHGCASAALDAAAAAPRDGGADAGVSARCPTCSSMFTSAQLVPNAAVNAMVAAMKSGASEAAAASTSAEDGEDDLERLTPLVKTLSEKHRSLVLESRAVSREVLKEFLVESRARKQASAVALERELRCLDADIDAVRREIEALGGGARVSHERSDLHDKEVIAHAMEALGLTRPGESQIVIDESKRRRVLRQFSELQSWYSKRRSAERDDVTSDGGKSSGSALNGGRGYAPDSTTMEEFSTIIDTFKRYSNISIAAEIRGEEDASNPGAPVSSIEFDSTQEYFATAGVSKRIQFYNLEHVLEGSQQPADEINTRSKLTCLSYNKFVKHHIAASDYEGVVSVWDVEKKCSIIDFEEHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVC2</accession>
    <name>A4RVC2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Crossover junction endonuclease MUS81</fullName>
            <ecNumber evidence="13">3.1.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_92534</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with EME1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the XPF family.</text>
    </comment>
    <dbReference type="EC" id="3.1.22.-" evidence="13"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417114.1">
        <property type="nucleotide sequence ID" value="XM_001417077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVC2"/>
    <dbReference type="STRING" id="436017.A4RVC2"/>
    <dbReference type="GeneID" id="5000947"/>
    <dbReference type="Gramene" id="ABO95407">
        <property type="protein sequence ID" value="ABO95407"/>
        <property type="gene ID" value="OSTLU_92534"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92534"/>
    <dbReference type="eggNOG" id="KOG2379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_405133_0_0_1"/>
    <dbReference type="OMA" id="QNGYVEP"/>
    <dbReference type="OrthoDB" id="5963188at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048257">
        <property type="term" value="F:3'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20074">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033309">
        <property type="entry name" value="Mus81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047416">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451">
        <property type="entry name" value="CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451:SF0">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 13" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="15">
        <location>
            <begin position="391"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU369042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO95407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="679" mass="74882" checksum="DA627389921E5215" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVK5</accession>
    <name>A4RVK5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_31007</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417434.1">
        <property type="nucleotide sequence ID" value="XM_001417397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVK5"/>
    <dbReference type="SMR" id="A4RVK5"/>
    <dbReference type="STRING" id="436017.A4RVK5"/>
    <dbReference type="GeneID" id="5001377"/>
    <dbReference type="Gramene" id="ABO95727">
        <property type="protein sequence ID" value="ABO95727"/>
        <property type="gene ID" value="OSTLU_31007"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31007"/>
    <dbReference type="eggNOG" id="KOG2198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_4_3_1"/>
    <dbReference type="OMA" id="YRTVNFA"/>
    <dbReference type="OrthoDB" id="495429at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016428">
        <property type="term" value="F:tRNA (cytidine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000271">
        <property type="entry name" value="NOL1/NOP2/Sun family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057285">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023270">
        <property type="entry name" value="RCMT_NCL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25376">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02011">
        <property type="entry name" value="RCMTNCL1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="11">
        <location>
            <begin position="41"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="158"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="655" mass="72651" checksum="E6C8F113B1C944A1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVL3</accession>
    <name>A4RVL3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417160.1">
        <property type="nucleotide sequence ID" value="XM_001417123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVL3"/>
    <dbReference type="STRING" id="436017.A4RVL3"/>
    <dbReference type="GeneID" id="5001418"/>
    <dbReference type="Gramene" id="ABO95453">
        <property type="protein sequence ID" value="ABO95453"/>
        <property type="gene ID" value="OSTLU_31015"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31015"/>
    <dbReference type="eggNOG" id="KOG2020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_254252_0_0_1"/>
    <dbReference type="OMA" id="IAKRSWG"/>
    <dbReference type="OrthoDB" id="507337at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042565">
        <property type="term" value="C:RNA nuclear export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045478">
        <property type="entry name" value="Exportin-5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF3">
        <property type="entry name" value="EXPORTIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19273">
        <property type="entry name" value="Exportin-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="2">
        <location>
            <begin position="64"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-5 C-terminal" evidence="3">
        <location>
            <begin position="275"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1167"/>
            <end position="1196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1196" mass="127473" checksum="2786AAE7D840B3C3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVR6</accession>
    <name>A4RVR6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Complex I-ESSS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase ESSS subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_9512</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Complex I is composed of 45 different subunits. Interacts with BCAP31.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB11 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417193.1">
        <property type="nucleotide sequence ID" value="XM_001417156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVR6"/>
    <dbReference type="STRING" id="436017.A4RVR6"/>
    <dbReference type="GeneID" id="5001207"/>
    <dbReference type="Gramene" id="ABO95486">
        <property type="protein sequence ID" value="ABO95486"/>
        <property type="gene ID" value="OSTLU_9512"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9512"/>
    <dbReference type="eggNOG" id="ENOG502S12I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138649_3_0_1"/>
    <dbReference type="OMA" id="QERTNRY"/>
    <dbReference type="OrthoDB" id="2147978at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019329">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ESSS_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637:SF1">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10183">
        <property type="entry name" value="ESSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO95486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="96" mass="10473" checksum="815909417090C363" modified="2007-05-15" version="1" fragment="single">RAVCTAVRGAQRTSVRSYGAGPPGGYFAEGTQTGRNGYLFGETPPAPGKRRVWEDWEAPWYGALTLATAILCVGLQAKPDTRMTSWAREEAARRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVX7</accession>
    <name>A4RVX7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA mismatch repair protein MSH3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 9">DNA mismatch repair protein MSH3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_49314</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417225.1">
        <property type="nucleotide sequence ID" value="XM_001417188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVX7"/>
    <dbReference type="STRING" id="436017.A4RVX7"/>
    <dbReference type="GeneID" id="5001502"/>
    <dbReference type="Gramene" id="ABO95518">
        <property type="protein sequence ID" value="ABO95518"/>
        <property type="gene ID" value="OSTLU_49314"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49314"/>
    <dbReference type="eggNOG" id="KOG0218">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_0_2_1"/>
    <dbReference type="OMA" id="INMHAAR"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000004">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF122">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="10">
        <location>
            <begin position="744"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="916" mass="98512" checksum="6A8892B6E2049839" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVZ3</accession>
    <name>A4RVZ3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small nuclear ribonucleoprotein Sm D1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">snRNP core protein D1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_12445</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in splicing regulation. Facilitates post-transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the snRNP core protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417233.1">
        <property type="nucleotide sequence ID" value="XM_001417196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVZ3"/>
    <dbReference type="STRING" id="436017.A4RVZ3"/>
    <dbReference type="GeneID" id="5001395"/>
    <dbReference type="Gramene" id="ABO95526">
        <property type="protein sequence ID" value="ABO95526"/>
        <property type="gene ID" value="OSTLU_12445"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12445"/>
    <dbReference type="eggNOG" id="KOG3428">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123956_3_0_1"/>
    <dbReference type="OMA" id="CVNVSMN"/>
    <dbReference type="OrthoDB" id="9626941at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035194">
        <property type="term" value="P:regulatory ncRNA-mediated post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01724">
        <property type="entry name" value="Sm_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000008">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034102">
        <property type="entry name" value="Sm_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="9">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="114" mass="12418" checksum="F584A1E9F9766157" modified="2007-05-15" version="1">MKLVRFLQKLSNESVTIELKNGTTAHGTIMGVDVSMNTHLKQVKLTLKGKNPTAVEHLSVRGNTIRYYILPDSLNLDTLLVDDTPKQGKPRAKAAASAGRGRGRGRGRGRARPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW05</accession>
    <name>A4RW05_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24412</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417241.1">
        <property type="nucleotide sequence ID" value="XM_001417204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW05"/>
    <dbReference type="STRING" id="436017.A4RW05"/>
    <dbReference type="GeneID" id="5001330"/>
    <dbReference type="Gramene" id="ABO95534">
        <property type="protein sequence ID" value="ABO95534"/>
        <property type="gene ID" value="OSTLU_24412"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24412"/>
    <dbReference type="eggNOG" id="KOG2508">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_484320_0_0_1"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF102">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE JMJ31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="152"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="563" mass="62889" checksum="43E45DB97A395D44" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWG7</accession>
    <name>A4RWG7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417328.1">
        <property type="nucleotide sequence ID" value="XM_001417291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWG7"/>
    <dbReference type="GeneID" id="5001526"/>
    <dbReference type="Gramene" id="ABO95621">
        <property type="protein sequence ID" value="ABO95621"/>
        <property type="gene ID" value="OSTLU_92650"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92650"/>
    <dbReference type="HOGENOM" id="CLU_1241582_0_0_1"/>
    <dbReference type="OMA" id="FDACEVD"/>
    <dbReference type="OrthoDB" id="497843at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="206" mass="21956" checksum="9B082A4CA9CE8766" modified="2007-05-15" version="1">MATPRTPARARATARARVDARRATRARARGESARAATSENAGARVALVAGALAVSLARDVDVARAFVGDIALDDVRYEAMERCPENQYVPNKQKTTCLRFTARATNAVKGRTIESANVFGFVEDAQGNSAATVNADGNSRTVLASIDAPIPKGESDVHFVVTVFKDSLENNGPLRLKAFKAVGSVADIDKRFTPFDACEVDPDSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWI0</accession>
    <name>A4RWI0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417581.1">
        <property type="nucleotide sequence ID" value="XM_001417544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWI0"/>
    <dbReference type="STRING" id="436017.A4RWI0"/>
    <dbReference type="GeneID" id="5001532"/>
    <dbReference type="Gramene" id="ABO95874">
        <property type="protein sequence ID" value="ABO95874"/>
        <property type="gene ID" value="OSTLU_15158"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15158"/>
    <dbReference type="eggNOG" id="KOG2394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_697167_0_0_1"/>
    <dbReference type="OMA" id="FILPEPQ"/>
    <dbReference type="OrthoDB" id="3367at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051362">
        <property type="entry name" value="WD_repeat_creC_regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107:SF16">
        <property type="entry name" value="AT02583P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="396" mass="43062" checksum="A35110D9902CE338" modified="2007-05-15" version="1">MALDEANDAKTAASVTFGGACVTSLAWRAKEEGERCDLLVGLANGEVCGVDLGRWLGEKAKRATATTTRWNADGDGVNASRTTCVRWRTRGDDKENLATGFDFVSLHADGSMYTYDSSKDVVAAKFEALADASALSVAASQVPGSNPSARWHFGRHTLNAAAFSPDCRYLVVVNGAGMCRVLDVELDRPNIVAGFKSYYAGFNAVTWSPCGRYVIAGGESDMLEIWGLYEREVVAWGCGGHRSWITDVAVDERAAGEGHRFLRIASVGEDCRVAFWDWHFPEDDDFGETAARDSNTATLADQASRLSVGAARASRRAPSFVGPDANIVQSAHRDEVERLVPIMTHKLHTSPVTAVRFTAEAALTATLNEIKLWRRPSHPSRYVHDDDHEESDLGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWS5</accession>
    <name>A4RWS5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA-(apurinic or apyrimidinic site) endonuclease</fullName>
            <ecNumber evidence="12">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_31440</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9 12">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9 12">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="12"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417629.1">
        <property type="nucleotide sequence ID" value="XM_001417592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWS5"/>
    <dbReference type="STRING" id="436017.A4RWS5"/>
    <dbReference type="GeneID" id="5001581"/>
    <dbReference type="Gramene" id="ABO95922">
        <property type="protein sequence ID" value="ABO95922"/>
        <property type="gene ID" value="OSTLU_31440"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31440"/>
    <dbReference type="eggNOG" id="KOG1294">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010374_3_0_1"/>
    <dbReference type="OMA" id="SFWICPR"/>
    <dbReference type="OrthoDB" id="391817at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF4">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GRF-type" evidence="14">
        <location>
            <begin position="422"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="10">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="10">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO95922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="474" mass="52618" checksum="B52780EDB382B5DE" modified="2007-05-15" version="1">MKALFDALGSDLKVICLQETKLSSSGDVERLERVEGWDGAHAVCESSNHRVGYSGVAVYWRSNEICPTSIERGVCAKGDAGESTMWAGEIAPFADDATRAKEIDGEGRALWVDFGEFVLCTVYVPAVFGDPAVDEKTAERAAFKRDFLSALEARYKSLRERGRNVILCGDWNIAPSWKLDRADEDPNAVEPRNPSRDWLAAQLAGDAMVDVFREFFPTLGDAFTCWNVASGAQLSNYGSRIDYFLCDRAVTLKRVRGVGVAQKFEGSDHAPVYLELEESMWRRRDSQQTPPSLAISMLYPGRQTTVDSIFARASSTSNATPEFLNAASQSRAKPTRPSARAQSRAGVSDAPKRKPEATLKDFFVVKSKKKEPDDRNERQLDTVEQPIAPTANAFESRETKVSSEEARGAWMNTFAKMAPPKCKHGETCKVRTVKKKESPHCGRVFFCCPRPAGARTNPDCDCGFFLWREHRAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWY3</accession>
    <name>A4RWY3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417658.1">
        <property type="nucleotide sequence ID" value="XM_001417621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWY3"/>
    <dbReference type="GeneID" id="5001753"/>
    <dbReference type="Gramene" id="ABO95951">
        <property type="protein sequence ID" value="ABO95951"/>
        <property type="gene ID" value="OSTLU_24501"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24501"/>
    <dbReference type="HOGENOM" id="CLU_1527658_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="176" mass="18749" checksum="8A79BC8560C03697" modified="2007-05-15" version="1">MMEDDARTYETDDSDGSDTVTALIERTTETEKITRDYCATEDSARERTGDANASDAMIEALEGKIKACEGASASGKGAQALYAKKAAAETALGKLSDALTSSKRVIEIAPLWFRGYVLLSEVTLRQCCDSSSVNDVDAAKEIAKAALERALFLEPNVSKDSKFLSLCAKIGAMSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWZ2</accession>
    <name>A4RWZ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_8794</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417662.1">
        <property type="nucleotide sequence ID" value="XM_001417625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWZ2"/>
    <dbReference type="STRING" id="436017.A4RWZ2"/>
    <dbReference type="GeneID" id="5002072"/>
    <dbReference type="Gramene" id="ABO95955">
        <property type="protein sequence ID" value="ABO95955"/>
        <property type="gene ID" value="OSTLU_8794"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8794"/>
    <dbReference type="eggNOG" id="KOG0105">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_34_5_1"/>
    <dbReference type="OMA" id="VEVHYLY"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="55"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="129" mass="14658" checksum="1FF2DF487472B2DE" modified="2007-05-15" version="1" fragment="single">RAVYVGNLPLDASSRDVDRRFAAHGVVARVEVKRPRHPPAFAFVTFDDARDAERAARAEDGTTFDGRRGPYDRPRWRDGADARSMVRERAATRKTEHSVKVEDLPRGADWRDVKDAFRRAGRVTYASTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX31</accession>
    <name>A4RX31_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417924.1">
        <property type="nucleotide sequence ID" value="XM_001417887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX31"/>
    <dbReference type="GeneID" id="5001685"/>
    <dbReference type="Gramene" id="ABO96217">
        <property type="protein sequence ID" value="ABO96217"/>
        <property type="gene ID" value="OSTLU_15310"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15310"/>
    <dbReference type="eggNOG" id="ENOG502R374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_812317_0_0_1"/>
    <dbReference type="OrthoDB" id="10448719at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672005" evidence="2">
        <location>
            <begin position="24"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37154" checksum="ABBB076FE2EF685A" modified="2007-05-15" version="1">MGRWRGRVGAAAAAACVGALALARRGWDGGFGIGAESPPAPPMPPPMPPPTPPMPPPTPPPPHPHHPPRPPPPPKVDCDASHGDRAIGLYQQYNKHCTDDEGVPSNCVGSHGCQFCHLAGSEASKEGSGTAKCSSWVCDKYEVSGCEGVETRSKEKKYDLGDCSTDVGNRNAGRHAFRDWECANHEGVPSACQKPGETPCRMCMLKSVDDPMDGWPYCPPAVCDDLNIHATECPGVDYVAKIGHSHHHSKHSKHSKHSHRDEEEEEEEEEEEEEEEEKSTKLSSKHSSSKKHHSSSHSSKDDDVEDDADVSEHLSKKKHGSSTRSATDELDEEFQKLKTSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX43</accession>
    <name>A4RX43_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417693.1">
        <property type="nucleotide sequence ID" value="XM_001417656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX43"/>
    <dbReference type="STRING" id="436017.A4RX43"/>
    <dbReference type="GeneID" id="5001978"/>
    <dbReference type="Gramene" id="ABO95986">
        <property type="protein sequence ID" value="ABO95986"/>
        <property type="gene ID" value="OSTLU_24511"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24511"/>
    <dbReference type="eggNOG" id="KOG0548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_957762_0_0_1"/>
    <dbReference type="OMA" id="TRIMMIT"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF533">
        <property type="entry name" value="HSP70-HSP90 ORGANIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="291" mass="31220" checksum="976EF912300D32B6" modified="2007-05-15" version="1">MSDSAARVTAARRAKERGSDLYKSGKWRDAADAFGEAIKIAPRDDEDVAVYHSNRAAALLQLGDAKAARSDAEKCVRLRPHWARGWSRVAAACEMLQDDAGAERALEKLISLDADNADARRNLNAVRARMRERGGASRGWRMPSMPSMPSMPSMPDVSATAAAGAAFCRMRYARATPNEQLAVKCALGVLAYFVFKRVASVFGFGGYGYGSYGGGYDPYDGGGFSLYTLLGVVALYYAHKSGASWWNLLSIANMFGLTGGGRRRGYGGYGGYGGYGGYGRPGFGGPGMFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX59</accession>
    <name>A4RX59_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_92718</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SFH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417938.1">
        <property type="nucleotide sequence ID" value="XM_001417901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX59"/>
    <dbReference type="GeneID" id="5002052"/>
    <dbReference type="Gramene" id="ABO96231">
        <property type="protein sequence ID" value="ABO96231"/>
        <property type="gene ID" value="OSTLU_92718"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92718"/>
    <dbReference type="eggNOG" id="KOG1471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084964_0_0_1"/>
    <dbReference type="OMA" id="HVIDMKG"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="5">
        <location>
            <begin position="12"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="280" mass="30948" checksum="E97591982A281705" modified="2007-05-15" version="1">MKSWEAVSAESREHMYEGYQGGWYTANTPLGVPVYVERLGTLDVEKMLKTASVEDIVGQRMRMQGYMIKTLLPEMARRPGSIARDKIVHVIDMKGAGLSLLSSRNIAVFKRLQEVDANFPEFLYRTYVVNVPIGARVVWSTFSAILPSRVRAKVRILGSVKRGNLTKLAAIMGGVDRVPEFLGGNCKRKLNECPPWSLQHMNDTTFVPWEKNVSLTKLAVSTPLSPNSFSRAHASPRGADDDAISYKTPRSASMATPTSVKKSNSAVKRLFSLKSPGKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY13</accession>
    <name>A4RY13_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kringle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_9500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417848.1">
        <property type="nucleotide sequence ID" value="XM_001417811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY13"/>
    <dbReference type="STRING" id="436017.A4RY13"/>
    <dbReference type="GeneID" id="5002083"/>
    <dbReference type="Gramene" id="ABO96141">
        <property type="protein sequence ID" value="ABO96141"/>
        <property type="gene ID" value="OSTLU_9500"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9500"/>
    <dbReference type="HOGENOM" id="CLU_158332_0_0_1"/>
    <dbReference type="OrthoDB" id="272018at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00108">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.20.10">
        <property type="entry name" value="Plasminogen Kringle 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000001">
        <property type="entry name" value="Kringle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013806">
        <property type="entry name" value="Kringle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018056">
        <property type="entry name" value="Kringle_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038178">
        <property type="entry name" value="Kringle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050759">
        <property type="entry name" value="Serine_protease_kringle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261:SF7">
        <property type="entry name" value="KRINGLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261">
        <property type="entry name" value="PLASMINOGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00051">
        <property type="entry name" value="Kringle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00018">
        <property type="entry name" value="KRINGLE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00130">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kringle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0420">Kringle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kringle" evidence="3">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="74" mass="8577" checksum="3398EF4D6C43D13B" modified="2007-05-15" version="1" fragment="single">EGYRGCQTRTRNGRTCQQWDSQSPHGHSRRNCAKGSCGRGNNYCRNPDGEPTIWCYTTNRNVRWEYCDPLPQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYE6</accession>
    <name>A4RYE6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418370.1">
        <property type="nucleotide sequence ID" value="XM_001418333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYE6"/>
    <dbReference type="GeneID" id="5002256"/>
    <dbReference type="Gramene" id="ABO96663">
        <property type="protein sequence ID" value="ABO96663"/>
        <property type="gene ID" value="OSTLU_32001"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32001"/>
    <dbReference type="HOGENOM" id="CLU_2473076_0_0_1"/>
    <dbReference type="OMA" id="RRYRPNC"/>
    <dbReference type="OrthoDB" id="10555154at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="88" mass="9428" checksum="EAE6629273D7C4FF" modified="2007-05-15" version="1">MGVWAHIDARVGIDESRSSATETVVETEVRVKIAAEVPRLLRAIPGFSKAATMTIGRSIDIVGGGIDDAAQRTYDRWAAQRGTASVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYX8</accession>
    <name>A4RYX8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_8006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418471.1">
        <property type="nucleotide sequence ID" value="XM_001418434.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYX8"/>
    <dbReference type="GeneID" id="5002490"/>
    <dbReference type="Gramene" id="ABO96764">
        <property type="protein sequence ID" value="ABO96764"/>
        <property type="gene ID" value="OSTLU_8006"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8006"/>
    <dbReference type="eggNOG" id="ENOG502RZVV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148546_1_0_1"/>
    <dbReference type="OMA" id="MIVQGRA"/>
    <dbReference type="OrthoDB" id="193238at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011719">
        <property type="entry name" value="CHP02058"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02058">
        <property type="entry name" value="lin0512_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34784">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34784:SF1">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09585">
        <property type="entry name" value="Lin0512_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="12937" checksum="AE7FFEBCDAD70E6A" modified="2007-05-15" version="1" fragment="single">PRGFERALFAECGFGADQHGQDATKAAVRACRNAIEFNSVPSVRAVVPGGYAKMKIHVQLGVPENAKVDAGRVREVFPYGEVVDVQIDTGGLRARSWISIPAQGDANDDFLICVACVTVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYY4</accession>
    <name>A4RYY4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEATR5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418473.1">
        <property type="nucleotide sequence ID" value="XM_001418436.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RYY4"/>
    <dbReference type="GeneID" id="5002494"/>
    <dbReference type="Gramene" id="ABO96766">
        <property type="protein sequence ID" value="ABO96766"/>
        <property type="gene ID" value="OSTLU_92899"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92899"/>
    <dbReference type="eggNOG" id="KOG1822">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_238850_0_0_1"/>
    <dbReference type="OMA" id="ETNSICI"/>
    <dbReference type="OrthoDB" id="512736at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046837">
        <property type="entry name" value="Laa1/Sip1/HEATR5-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044218">
        <property type="entry name" value="SWEETIE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46975">
        <property type="entry name" value="PROTEIN SWEETIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46975:SF2">
        <property type="entry name" value="PROTEIN SWEETIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20210">
        <property type="entry name" value="Laa1_Sip1_HTR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1770" mass="189695" checksum="F8813E7C972BB58A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYY9</accession>
    <name>A4RYY9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418475.1">
        <property type="nucleotide sequence ID" value="XM_001418438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYY9"/>
    <dbReference type="STRING" id="436017.A4RYY9"/>
    <dbReference type="GeneID" id="5002497"/>
    <dbReference type="Gramene" id="ABO96768">
        <property type="protein sequence ID" value="ABO96768"/>
        <property type="gene ID" value="OSTLU_24679"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24679"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1345172_0_0_1"/>
    <dbReference type="OMA" id="NDCLERW"/>
    <dbReference type="OrthoDB" id="2018540at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029159">
        <property type="entry name" value="CA109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038985">
        <property type="entry name" value="OPRN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37904">
        <property type="entry name" value="OS10G0566900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37904:SF2">
        <property type="entry name" value="OS10G0566900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15011">
        <property type="entry name" value="CA109-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="204" mass="22807" checksum="4461885884B26741" modified="2007-05-15" version="1">METFLNAFRDAYGALARCRARWDDAQGASVALLGTAVNAFERLPAIHDAARARAVDGSEILIDDAFASRVVEAQYAALDRVFARLREECARFDALTRELERAKTDAWTRTRNLKPPPKRAGGERSGPQPSIADCVLGLEEAWRMHKDECALKREIVKRASTCEDAEELKMLLRLFSAQPNLDPEELRLIADRVPVKNVEADTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZB0</accession>
    <name>A4RZB0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_12653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418543.1">
        <property type="nucleotide sequence ID" value="XM_001418506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZB0"/>
    <dbReference type="STRING" id="436017.A4RZB0"/>
    <dbReference type="GeneID" id="5002180"/>
    <dbReference type="Gramene" id="ABO96836">
        <property type="protein sequence ID" value="ABO96836"/>
        <property type="gene ID" value="OSTLU_12653"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12653"/>
    <dbReference type="eggNOG" id="KOG2981">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027518_0_0_1"/>
    <dbReference type="OMA" id="HCPTWSW"/>
    <dbReference type="OrthoDB" id="1584384at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044804">
        <property type="term" value="P:nucleophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="290" mass="31624" checksum="2D2D93F716736CD4" modified="2007-05-15" version="1">MHALRHAVHGAYKTTMEAVTPIRSSSAFASEGVLTPEEFVAAGDALTRACPTWTWTTGQGARARTYLPREKQYLTTRRVPCARRARDVEAYAGAEEALTGEDEGWIATGAGGRSDGATMEAIPDLGAMTLEADAEDDAEDEYEDEDDDAVVLPTATAIAKEAAGANGERDDENIVKTRTYDVSITYDKYYQTPRVWLNGYDENRLVLKPSKTLEDISADHAQKTVTIDPHPHTGVPSASIHPCKHASVMKKLVNSARAQSGEAPSVDSYMFVFLKFIASVVPTIEYDYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZE5</accession>
    <name>A4RZE5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SM/Sec1-family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_40796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418316.1">
        <property type="nucleotide sequence ID" value="XM_001418279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZE5"/>
    <dbReference type="STRING" id="436017.A4RZE5"/>
    <dbReference type="GeneID" id="5002368"/>
    <dbReference type="Gramene" id="ABO96609">
        <property type="protein sequence ID" value="ABO96609"/>
        <property type="gene ID" value="OSTLU_40796"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40796"/>
    <dbReference type="eggNOG" id="KOG1301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016216_3_1_1"/>
    <dbReference type="OMA" id="VNDLRAW"/>
    <dbReference type="OrthoDB" id="10251230at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="641" mass="69401" checksum="163E1E75EA9BBC3D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S058</accession>
    <name>A4S058_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidoglycan binding-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_16127</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418685.1">
        <property type="nucleotide sequence ID" value="XM_001418648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S058"/>
    <dbReference type="STRING" id="436017.A4S058"/>
    <dbReference type="GeneID" id="5002969"/>
    <dbReference type="Gramene" id="ABO96978">
        <property type="protein sequence ID" value="ABO96978"/>
        <property type="gene ID" value="OSTLU_16127"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16127"/>
    <dbReference type="HOGENOM" id="CLU_433205_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="PGBD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidoglycan binding-like" evidence="3">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="409"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="632" mass="69199" checksum="8CD6B98B84C189F1" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S098</accession>
    <name>A4S098_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Magnesium-protoporphyrin IX methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_35500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418936.1">
        <property type="nucleotide sequence ID" value="XM_001418899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S098"/>
    <dbReference type="STRING" id="436017.A4S098"/>
    <dbReference type="GeneID" id="5002693"/>
    <dbReference type="Gramene" id="ABO97229">
        <property type="protein sequence ID" value="ABO97229"/>
        <property type="gene ID" value="OSTLU_35500"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35500"/>
    <dbReference type="eggNOG" id="KOG1270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066342_1_0_1"/>
    <dbReference type="OMA" id="LAWVKND"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046406">
        <property type="term" value="F:magnesium protoporphyrin IX methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010251">
        <property type="entry name" value="Mg_prot_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010940">
        <property type="entry name" value="Mg_prot_MeTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02021">
        <property type="entry name" value="BchM-ChlM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07109">
        <property type="entry name" value="Mg-por_mtran_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51556">
        <property type="entry name" value="SAM_MT_MG_PIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Magnesium-protoporphyrin IX methyltransferase C-terminal" evidence="1">
        <location>
            <begin position="138"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="25752" checksum="36F23EB28414083C" modified="2007-05-15" version="1">MAETGGDEAASVKNYFDTTGFERWNKIYGETEDVNKVQLDIREGHQQTVDKVLAWVKNDDLEGVTVCDAGCGTGSLAIPLALQGANVSASDISSSMVGEAERRYKELVANGAKAPATEPKFDAMGLEEATGKYDMVTCIDVMIHYPKDRVDGMINHLASLSSKKLIISFAPKTLAYLILKRVGELFPGPSKATRAYLHDEADVEIALKAAGFKVKRREMTATSFYFSRLLECERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0H4</accession>
    <name>A4S0H4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_32748</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418972.1">
        <property type="nucleotide sequence ID" value="XM_001418935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0H4"/>
    <dbReference type="STRING" id="436017.A4S0H4"/>
    <dbReference type="GeneID" id="5002772"/>
    <dbReference type="Gramene" id="ABO97265">
        <property type="protein sequence ID" value="ABO97265"/>
        <property type="gene ID" value="OSTLU_32748"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32748"/>
    <dbReference type="eggNOG" id="KOG0327">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
    <dbReference type="OMA" id="FTHRNGR"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17939">
        <property type="entry name" value="DEADc_EIF4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="71"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="252"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="413" mass="46710" checksum="28503F351C9F08A2" modified="2007-05-15" version="1">MSGEGGFDDANYDRGMEELLKDDQDENGEGGITEWTEVHETFDTMNLQENLLRGIYAYGFEKPSAIQQRGIVPFSKGFDVIQQAQSGTGKTATFCAGILQSLDYSVHECQALVLAPTRELAQQIEKVMRALGDYLQVKCHACVGGTSVREDTRILQAGVHVIVGTPGRVYDMLRRRALKSDSIKIFALDEADEMLSRGFKDQIYDIFTLLPPKVQVGVFSATLPPEALEITRKFMTKPVRILVKRDELTLEGIKQFYVNVDKEQWKLDTLCDLYETLAITQSVIFANTRRKVDWLTDNMRARDFTVSATHGDMDQNTRDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRSGRFGRKGVSINFVTAEDERLLQDIQRFYQTVIEELPSNVADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0H6</accession>
    <name>A4S0H6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_32750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type IV zinc-finger family. Class A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418973.1">
        <property type="nucleotide sequence ID" value="XM_001418936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0H6"/>
    <dbReference type="STRING" id="436017.A4S0H6"/>
    <dbReference type="GeneID" id="5002773"/>
    <dbReference type="Gramene" id="ABO97266">
        <property type="protein sequence ID" value="ABO97266"/>
        <property type="gene ID" value="OSTLU_32750"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32750"/>
    <dbReference type="eggNOG" id="KOG1601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_699055_0_0_1"/>
    <dbReference type="OMA" id="HCGTVKT"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="355"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="276"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="395" mass="43144" checksum="5BB80C74FA5E68EF" modified="2007-05-15" version="1">MGGHARARAAPGDFLGAKPSTRDFALEDLFRVDFASGDEGEGEGEKRATIDGGREGDAVRAAATREAREGRAAADDWDALARAWDEVEARAPARDYAWEVLNSLPSVGGDIMTCKEDEMDCFAYGGAHSVPYIAPEWLERPNGDVEDGVSDNEDEDEDEGDAHRFTKAMRESSSFLLDDEDEFMRTVDAPVDFITEPEAFAARREARALARDAREPAIDFAVKSALLCGDEEEDDFSGQDCSAMADESAYEFQEHFATAADGRVFRVSSALVTPSSSERANVEDSANHRGLTDSEDSDADLVAHSAKKSPKLIAGSTTKRKRRPDGRGRRAKAYKKIKKDKGVCATDVYVMANGKKMRRGCLHCGTVKTPQWRMGPEGKKTLCNACGVRYMKGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0H7</accession>
    <name>A4S0H7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CCR4-NOT transcription complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_32751</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418748.1">
        <property type="nucleotide sequence ID" value="XM_001418711.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S0H7"/>
    <dbReference type="GeneID" id="5002884"/>
    <dbReference type="Gramene" id="ABO97041">
        <property type="protein sequence ID" value="ABO97041"/>
        <property type="gene ID" value="OSTLU_32751"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32751"/>
    <dbReference type="eggNOG" id="KOG1831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000286_3_1_1"/>
    <dbReference type="OMA" id="IDEYHCY"/>
    <dbReference type="OrthoDB" id="1933107at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000012">
        <property type="entry name" value="Ccr4-Not transcription complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.800:FF:000001">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.840:FF:000003">
        <property type="entry name" value="Transcription regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="11">
        <location>
            <begin position="256"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="10">
        <location>
            <begin position="417"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="9">
        <location>
            <begin position="722"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="8">
        <location>
            <begin position="1019"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="7">
        <location>
            <begin position="1438"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="624"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1209"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="626"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1214"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1233"/>
            <end position="1264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1818" mass="197611" checksum="7CCB7DCADF244952" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0J1</accession>
    <name>A4S0J1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_35710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418984.1">
        <property type="nucleotide sequence ID" value="XM_001418947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0J1"/>
    <dbReference type="STRING" id="436017.A4S0J1"/>
    <dbReference type="GeneID" id="5002824"/>
    <dbReference type="Gramene" id="ABO97277">
        <property type="protein sequence ID" value="ABO97277"/>
        <property type="gene ID" value="OSTLU_35710"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35710"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_22_5_1"/>
    <dbReference type="OMA" id="MIYEADP"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="10"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="75" mass="8370" checksum="B3B3992B97597B64" modified="2007-05-15" version="1" fragment="single">MYAQPDAGGLSKDDIRQAFREFDLDRNGYVGAAEIAHVLASMGEKVTDDEIDEMILMADTDGDGQISFEEFHRLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0X1</accession>
    <name>A4S0X1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SDR family NAD(P)-dependent oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_10348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419052.1">
        <property type="nucleotide sequence ID" value="XM_001419015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0X1"/>
    <dbReference type="GeneID" id="5003384"/>
    <dbReference type="KEGG" id="olu:OSTLU_10348"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OMA" id="RMYTTSS"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="20482" checksum="405665D6639389EF" modified="2007-05-15" version="1" fragment="single">LAGKRVLVTGANRGVGLALCEELTRRGAEVVATCRRTSEALMALKPKEVIEDVDVTDAASCERMAKAVGGTLDIVVNNAGYFYEPVEKVTDGSMAFDEELKMIDICAVGPLRVSNALYNAGKITKGGKIAMVTSQGGSVTWREVQNPSGGDYGHHMSKAAANMGAKLLAQELKHEGIMVQVLHPGFNKTDMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Z1</accession>
    <name>A4S0Z1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_1909</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419059.1">
        <property type="nucleotide sequence ID" value="XM_001419022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Z1"/>
    <dbReference type="SMR" id="A4S0Z1"/>
    <dbReference type="STRING" id="436017.A4S0Z1"/>
    <dbReference type="GeneID" id="5003397"/>
    <dbReference type="Gramene" id="ABO97352">
        <property type="protein sequence ID" value="ABO97352"/>
        <property type="gene ID" value="OSTLU_1909"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1909"/>
    <dbReference type="eggNOG" id="KOG0660">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="HHKKGAP"/>
    <dbReference type="OrthoDB" id="2396at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07859">
        <property type="entry name" value="STKc_TDY_MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000017">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000046">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="17"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="356"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="387" mass="44347" checksum="9F4FCCFA9B92F304" modified="2007-05-15" version="1" fragment="single">TEFFANLRESSNESARYELEEVIGKGSYGVVCAAIDRQTGNRVAIKKVKNAFDHASDATRILREVTLLRHLKHPDIVEVLNIMLPPNPRDFNDVFIVFELMETDLHQVIKANDDLTDEHYQFFLYQLLRGLKYMHSANVFHRDLKPKNILANSDCKLKICDFGLARAMTAKAGPQMIFWTDYVATRWYRAPELCGSFFTKYTPAIDIWGVGCIFAELLRGKPLFPGKNVVKQLEIITDLLGTPTPLQIAKVRNEKARRFLQNMRIKPAVPLSEKFPGVDPKALNLLSKLLAFDPDDRPTAAQALADPYFDGLADVSREPARRPLPKDEFDWDSRKLSREEVRELLYKEILHYHPQAKREYEGNEKKSGFDYPSGVSDMAHKFNSLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1K7</accession>
    <name>A4S1K7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_42757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419166.1">
        <property type="nucleotide sequence ID" value="XM_001419129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1K7"/>
    <dbReference type="STRING" id="436017.A4S1K7"/>
    <dbReference type="GeneID" id="5003221"/>
    <dbReference type="Gramene" id="ABO97459">
        <property type="protein sequence ID" value="ABO97459"/>
        <property type="gene ID" value="OSTLU_42757"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42757"/>
    <dbReference type="eggNOG" id="KOG2422">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008321_4_0_1"/>
    <dbReference type="OMA" id="KERIWTD"/>
    <dbReference type="OrthoDB" id="205993at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006994">
        <property type="entry name" value="TCF25/Rqc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684">
        <property type="entry name" value="NULP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684:SF0">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04910">
        <property type="entry name" value="Tcf25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="378" mass="42881" checksum="BC18BFA5CC16325E" modified="2007-05-15" version="1">MVTSGVVDAESGMSDFSFAWKDDYAQANFDFEIAVGSHDPNRLFSLLNHYPWHLETLLRISELYHYSGQAQESSEILERCLYACERAWHPNFTAAASSGLAHLDASQPENKPMFEALFRHVIALTRRGCHKTALECAKLCLGLDHTDPKGMLHMISYFALRSGEEEWLLRFVEDFGHKRWVGGKWELHGSLLNFPDFAYSKAMALYTIADDIKVADAELLKAMLTYPYALTATLMRLEAAVSSDKDWKEILAHEHFDFSNCALDSRSLEHVSDIFATRHHLLWRPDPILHWAKRVARSAIQLVDSMKPSDMIDGLTAAEFVTISLQNWPASEENDFTHLVDDDFTDVVKRALPEDDPLAARGPNDPDHFSDDDDGDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1L1</accession>
    <name>A4S1L1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MC family transporter: Grave's disease carrier protein (GDC)-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_5965</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419169.1">
        <property type="nucleotide sequence ID" value="XM_001419132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1L1"/>
    <dbReference type="STRING" id="436017.A4S1L1"/>
    <dbReference type="GeneID" id="5003222"/>
    <dbReference type="KEGG" id="olu:OSTLU_5965"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_10_1_1"/>
    <dbReference type="OMA" id="VKQVPMH"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="109"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="219"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="294" mass="31493" checksum="9F945E6E68CD9B6F" modified="2007-05-15" version="1" fragment="single">LETLFSGAIAGAVAKSVVAPADRVKIIYQVDAQKQFTLNAALRTARQIIQTEGVPALWRGNGVQMIRVMPYAGVSFLAFPKYDAYMNKFTNLQLPSLLGIDPVENEDQLRIFSRFCAGAAAGATATTMTYPLDMLRARFAATGPAAKGPLADLASLVRSRGVLSLYSGLSPTLIGIIPYGGISFATFETLKAMHIKQAIKRAESIGEEISSTATLPVSVRLFYGGTAGLLAQSITYPLDVVRRRVQVLGKTGMSTREAIINIARTEGVRGLYKGLTMNWVKGPLSVAVSFAVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1P0</accession>
    <name>A4S1P0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419400.1">
        <property type="nucleotide sequence ID" value="XM_001419363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1P0"/>
    <dbReference type="GeneID" id="5003154"/>
    <dbReference type="Gramene" id="ABO97693">
        <property type="protein sequence ID" value="ABO97693"/>
        <property type="gene ID" value="OSTLU_33166"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33166"/>
    <dbReference type="HOGENOM" id="CLU_2101011_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="116" mass="13039" checksum="AD35A2289F820C18" modified="2007-05-15" version="1">MTTNALETFPNEYESSGVSRRLHRRASHSPPSSSRPKSTSAQGFEGSCKEYVIRLAIGYRYKLLFRASIAKRRTPQAHVRSRILHFDQTGLCEPAADAFVSCQPRRAGSSCRSSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Y3</accession>
    <name>A4S1Y3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_9445</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I NDUFA5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419446.1">
        <property type="nucleotide sequence ID" value="XM_001419409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Y3"/>
    <dbReference type="STRING" id="436017.A4S1Y3"/>
    <dbReference type="GeneID" id="5003144"/>
    <dbReference type="Gramene" id="ABO97739">
        <property type="protein sequence ID" value="ABO97739"/>
        <property type="gene ID" value="OSTLU_9445"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9445"/>
    <dbReference type="eggNOG" id="KOG3365">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099943_1_1_1"/>
    <dbReference type="OMA" id="ENQWKWP"/>
    <dbReference type="OrthoDB" id="286811at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006806">
        <property type="entry name" value="NDUFA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04716">
        <property type="entry name" value="ETC_C1_NDUFA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="97" mass="10740" checksum="6C600741D13911F5" modified="2007-05-15" version="1" fragment="single">KQTTGIVGLDVLDDAKATYEAICEEVLREVEVGIPSDAGYREAVTKLYAERLAKVRAGGSVREIEDAIGEGQIEEMYEAAKDELALIPKMRAWKPWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S253</accession>
    <name>A4S253_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_33328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419688.1">
        <property type="nucleotide sequence ID" value="XM_001419651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S253"/>
    <dbReference type="STRING" id="436017.A4S253"/>
    <dbReference type="GeneID" id="5003625"/>
    <dbReference type="Gramene" id="ABO97981">
        <property type="protein sequence ID" value="ABO97981"/>
        <property type="gene ID" value="OSTLU_33328"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33328"/>
    <dbReference type="eggNOG" id="KOG1491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018395_1_0_1"/>
    <dbReference type="OMA" id="PKMVVQG"/>
    <dbReference type="OrthoDB" id="424823at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF7">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="27"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="311"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="405" mass="45124" checksum="7448D671F6311F36" modified="2007-05-15" version="1">MPPKKKTADDGADDVGAAKFGRVRNNLRMGIVGLPNVGKSSLFNILTEQSIAAENYPFCTIDPNEARCPVPDARYDRLVSMWKPASEYPAFLSVTDIAGLVRGASSGAGLGNAFLSNIMATDGIFHVVRAFDDPEVVHVDDEIDPVRDLETITAELCLKDLETVKRAIADEERDVKKNPTMKLSALFKDTMARCTEMLENNLAIRTGEWNTPEVEMIKDKLPALLTTKPMIYLVNLSKRDYVRKKNKWLPKIHAWVQQHGGGIMIPFSVEFEQELFDLGDDESLRSAFYEENEGAKSALPKMVTQGYKELNLMYFFTAGEKEVRCWTVYNGALAPQAAGVIHTDFEKGFIKAEVCSYDDFAAIATKPSMAEVKEAGKYRQEGKAYVVKDGDIIHFQIGQLTKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S266</accession>
    <name>A4S266_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_5471</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S266"/>
    <dbReference type="STRING" id="436017.A4S266"/>
    <dbReference type="GeneID" id="5003903"/>
    <dbReference type="KEGG" id="olu:OSTLU_5471"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_14_1"/>
    <dbReference type="OMA" id="DYSCLAM"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WD40_repeat_CS"/>
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        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
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    </dbReference>
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        <property type="match status" value="6"/>
    </dbReference>
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        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
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        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="24"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="66"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="107"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="147"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="230"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="264" mass="29772" checksum="6EB409419F5B9C9F" modified="2007-05-15" version="1" fragment="single">LFSASADKTIRAWDISSRRCVQVLEEHTRPVLCLAVCVKHDKLFSGSYDCTVRVWNLSTYRRITYLPGHTDAVRALQVYNDTTLYTASYDHTIRAYDIESLELLKVLRGHNGPVRTLVTVNDYVFSGSYDRTVRVWPAYTADCVQELKGHGDNVRVLTVDDRHLYSGSWDKTIRVWDLETFSCKHIINGHTEAVLALCVMGGHLVSGSYDTTVRLWGVQPETEFECVGVFQGHHDAVRVLTSAGRNATTVFSGSYDGSIGFWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S295</accession>
    <name>A4S295_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_34773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419494.1">
        <property type="nucleotide sequence ID" value="XM_001419457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S295"/>
    <dbReference type="STRING" id="436017.A4S295"/>
    <dbReference type="GeneID" id="5003582"/>
    <dbReference type="Gramene" id="ABO97787">
        <property type="protein sequence ID" value="ABO97787"/>
        <property type="gene ID" value="OSTLU_34773"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34773"/>
    <dbReference type="eggNOG" id="KOG1816">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037790_0_1_1"/>
    <dbReference type="OMA" id="YVEPAFE"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="5">
        <location>
            <begin position="109"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="323"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="355" mass="38578" checksum="25D990892D832BC1" modified="2007-05-15" version="1">MFSRFGVGQARFNASYRAYPVSFIDRPQLELGDKVILPPSALERLTRMQIDDYPMLFEVTNAKEGKSTHCGVLEFVADEGVVYLPYWMMQNLLLGEGDIVKFSYSTLPKGTYVKLQPQTQDFLDISNPKAVLETTLRQYTCLTVGDTFVIHYNNKQYHIDVIEAKPGDAIGVVDTDCEVDFAPPLDYVDPYGPDTTKFEDTNSGAINAPKTADKADAGASGDAATNGETLAAPQPVVNTFLAFAGGGHRLDGKAISEIAPKEVEIPTSSLNVTKEWQQLRQGGVLGGETSKEPEKPAPDADIDRKRSGKVVFGGARAAAIARKKEKAAVAKKDDSSKDKPTSTFQAFQGSGNKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2D3</accession>
    <name>A4S2D3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419510.1">
        <property type="nucleotide sequence ID" value="XM_001419473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2D3"/>
    <dbReference type="GeneID" id="5003545"/>
    <dbReference type="Gramene" id="ABO97803">
        <property type="protein sequence ID" value="ABO97803"/>
        <property type="gene ID" value="OSTLU_33412"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33412"/>
    <dbReference type="eggNOG" id="ENOG502QRQG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1084070_0_0_1"/>
    <dbReference type="OMA" id="HVCEAIT"/>
    <dbReference type="OrthoDB" id="496771at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21385:SF0">
        <property type="entry name" value="RE51073P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21385">
        <property type="entry name" value="ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="31308" checksum="EC41852D15E06B34" modified="2007-05-15" version="1">MSEATDATRSSSGLAATCSRERSRAARTVLNEFFYPVADGARYALDLGCPFSHARDLFYEHETHKEPVRHSKLYWRSLYSGKVFKSEYYVDKHMERRHGDKIPSTADVCLADYCDVLQCDKHAEYVKNGRGSKPTRCDEEQMSLVRDKCHEMLTQCFPNENGSTRDNAGKLNVYFTKYYCDQMTCADVDGVFELMSAHHDSPGVGYYIALAFLFFIVAMYYLTVYSWTNGRRVSSDIKRARVRARASWSDYLPRPVARRFNLERRKRKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2J4</accession>
    <name>A4S2J4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_10093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419761.1">
        <property type="nucleotide sequence ID" value="XM_001419724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2J4"/>
    <dbReference type="STRING" id="436017.A4S2J4"/>
    <dbReference type="GeneID" id="5003598"/>
    <dbReference type="Gramene" id="ABO98054">
        <property type="protein sequence ID" value="ABO98054"/>
        <property type="gene ID" value="OSTLU_10093"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10093"/>
    <dbReference type="eggNOG" id="KOG0231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032017_4_0_1"/>
    <dbReference type="OMA" id="EMYEGYW"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="315" mass="35864" checksum="55B8E32B4F8AC540" modified="2007-05-15" version="1" fragment="single">LEYTNGDEYVGECVDETRHGRGRHVCSTGDVYDGYWRDDKRHGRGTMTFKSGLKYEGEWEDDKTCGRGRCEYVNGDVYEGEWKNDHRWGWGTQRFASGDVYEGEWVDDIVEGNGMYTYADGSTFNGATLSGSRVRGRYAAKDGSVEYDGEWRGDYRHGRGKFAAVGSYKYIGQWRDDLRHGRGKCELATGSTYDGEWRDDQYHGKGVLKTATFEYVGDFEGGRRKGQGVCKFTDLGEEYRGAFDEDAENGKGKRLYADGTIYQGEWCDGKRHGKGACTYANGDEYQGEWVRDERHGYGVCVFADGTKYRGEWERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2M1</accession>
    <name>A4S2M1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_1394</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419557.1">
        <property type="nucleotide sequence ID" value="XM_001419520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2M1"/>
    <dbReference type="STRING" id="436017.A4S2M1"/>
    <dbReference type="GeneID" id="5003613"/>
    <dbReference type="KEGG" id="olu:OSTLU_1394"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_104_15_1"/>
    <dbReference type="OMA" id="PQHAIGD"/>
    <dbReference type="OrthoDB" id="21225at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF5">
        <property type="entry name" value="HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="31"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="432"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="9">
        <location>
            <position position="487"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="550" mass="61028" checksum="85AA4C18FEDDBC97" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2V0</accession>
    <name>A4S2V0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NIF system FeS cluster assembly NifU C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_9865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419810.1">
        <property type="nucleotide sequence ID" value="XM_001419773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2V0"/>
    <dbReference type="STRING" id="436017.A4S2V0"/>
    <dbReference type="GeneID" id="5003760"/>
    <dbReference type="Gramene" id="ABO98103">
        <property type="protein sequence ID" value="ABO98103"/>
        <property type="gene ID" value="OSTLU_9865"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9865"/>
    <dbReference type="eggNOG" id="KOG2358">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060555_4_3_1"/>
    <dbReference type="OMA" id="GCPSTTI"/>
    <dbReference type="OrthoDB" id="565552at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000003">
        <property type="entry name" value="NifU-like protein 3, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF1">
        <property type="entry name" value="NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU C-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="7724" checksum="F5AA5C97C22A2DD3" modified="2007-05-15" version="1" fragment="single">TMENVDEALDEVRPYLVADGGNVELVKIEGKIIVVRLNGACGTCASSSATMKGGIEKLLKQKFGDAVEEVVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Y4</accession>
    <name>A4S2Y4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419617.1">
        <property type="nucleotide sequence ID" value="XM_001419580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Y4"/>
    <dbReference type="STRING" id="436017.A4S2Y4"/>
    <dbReference type="ESTHER" id="ostlu-a4s2y4">
        <property type="family name" value="Duf_1350"/>
    </dbReference>
    <dbReference type="GeneID" id="5003828"/>
    <dbReference type="Gramene" id="ABO97910">
        <property type="protein sequence ID" value="ABO97910"/>
        <property type="gene ID" value="OSTLU_33610"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33610"/>
    <dbReference type="eggNOG" id="ENOG502SRV8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047079_1_0_1"/>
    <dbReference type="OMA" id="VYDQEAM"/>
    <dbReference type="OrthoDB" id="3980at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010765">
        <property type="entry name" value="DUF1350"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34127">
        <property type="entry name" value="OS04G0405600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34127:SF1">
        <property type="entry name" value="OS04G0405600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07082">
        <property type="entry name" value="DUF1350"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="37697" checksum="008F9CB36CDDC141" modified="2007-05-15" version="1">MVRLTTALRRIDDAKSRDGGGAWRVCEATGARVRAPRAKTPWGCVHFVGGAVLGSFPDVAYDAWLSACADDVGLVVVATPYELDLDHEKCAMAVKKTYDEARRLACAKEGMDASRAPTFRVGHSLGCKLLCLVASAEDANEREGNGEAGDGTIDMDVDATSGTAVAVSGTTRGGVGNVAGHFLVAFNNADATDSVKLVEKFARELLKKRAGAASGASEEFFKTLPNLAAFAERAAKAAGLEFKPTPAQTLERCRTRFASKRVRLIKFKDDDLDQNDELLEVLRERMKVYPGRVDARELDFGNHLTPVYFSTDGLKLTPALEKLVGQFALGDAEGVRKLSAEFAAFIRDASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S318</accession>
    <name>A4S318_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419637.1">
        <property type="nucleotide sequence ID" value="XM_001419600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S318"/>
    <dbReference type="STRING" id="436017.A4S318"/>
    <dbReference type="GeneID" id="5003842"/>
    <dbReference type="Gramene" id="ABO97930">
        <property type="protein sequence ID" value="ABO97930"/>
        <property type="gene ID" value="OSTLU_16888"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16888"/>
    <dbReference type="eggNOG" id="KOG2956">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_300243_0_0_1"/>
    <dbReference type="OMA" id="SGNACIR"/>
    <dbReference type="OrthoDB" id="46159at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CLIP-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <location>
            <begin position="225"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="754"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="461"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="998" mass="107525" checksum="56140DA65E3579B1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3H4</accession>
    <name>A4S3H4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyltransferase family 32 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3H4"/>
    <dbReference type="STRING" id="436017.A4S3H4"/>
    <dbReference type="CAZy" id="GT32">
        <property type="family name" value="Glycosyltransferase Family 32"/>
    </dbReference>
    <dbReference type="GeneID" id="5004250"/>
    <dbReference type="Gramene" id="ABO98211">
        <property type="protein sequence ID" value="ABO98211"/>
        <property type="gene ID" value="OSTLU_26056"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26056"/>
    <dbReference type="eggNOG" id="ENOG502QW2I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023604_0_0_1"/>
    <dbReference type="OMA" id="GHVGPAC"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
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        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="717" mass="80592" checksum="BA00BCD67CD2B5CA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3T9</accession>
    <name>A4S3T9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419941.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S3T9"/>
    <dbReference type="GeneID" id="5004017"/>
    <dbReference type="Gramene" id="ABO98271">
        <property type="protein sequence ID" value="ABO98271"/>
        <property type="gene ID" value="OSTLU_94871"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94871"/>
    <dbReference type="HOGENOM" id="CLU_1149719_0_0_1"/>
    <dbReference type="OrthoDB" id="498535at2759"/>
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        <property type="component" value="Chromosome 10"/>
    </dbReference>
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        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="242" mass="26234" checksum="3767D70461FD1364" modified="2007-05-15" version="1" fragment="single">AQLQGAEFKAQGVYSAQAGTTVTVRMQPRDRFGNTTAWKSWQTLSVTASGTEDITFTEIDDQEAVSSRGVFSATFSKAGAYVVWVTVGGQTIVGWPRVVQIIPGTTNANVSQLRPEADSMALAAELVRHGGNDASLIDALGRQSTDVDKLRGEMIALKQKLASYERAEHDARQRGTIDPTATALTTEQVDKKNMKTMQLMVAETESDRGTLDSANDDDEFGDASPFYDDNVDDAEFEDARSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S446</accession>
    <name>A4S446_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS family transporter: multidrug efflux</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_93385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420205.1">
        <property type="nucleotide sequence ID" value="XM_001420168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S446"/>
    <dbReference type="GeneID" id="5004181"/>
    <dbReference type="Gramene" id="ABO98498">
        <property type="protein sequence ID" value="ABO98498"/>
        <property type="gene ID" value="OSTLU_93385"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93385"/>
    <dbReference type="eggNOG" id="KOG2615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_461816_0_0_1"/>
    <dbReference type="OMA" id="MVWITIC"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF117">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="506" mass="53321" checksum="EEE8841FA171EDD8" modified="2007-05-15" version="1">MTRRRAFEFARAPADETPLDWRTIAVVQMFSMLSIAGTTALFSTAYFAARALRPEASEASRALVAGALTATKPLASGASSLAWGRLGDARGFERAICASGVAHAIATAAFAMARTTSGAFAARACQGLADGMVVMQKPALALVSDETNVARAFATTGVAYGVASALAPALAAALSEPCENWKAFEGERGARCPTFLRRRPFFLSNIWIAALAAPTLMAYARGWMQIDKHRNRDDVEVVVELELLPDASEDDAAAETTAVDADAAAATKKAVESIEDEVVWWRDVNVRAAIASQVGCTAVVLCGAEMTPLWMATSVANGGLGWTSLEIGAFGTVMGCVILLFQVFLFTRLCRAYGIVTLLTYALLVNAVAFPLHPIAHVAAKKSKAWTWVAVVCLGLARGMSGPIIMGGSSLILNNASPRDTLGAVNGFSGTFGNAARGVAPLIGGSLVAMMVAMKPGTPGRDVWPFVVIGLGFVSLTVLSRRLSLDLNKPRRPRRTSSRSDFSAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4D9</accession>
    <name>A4S4D9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_44053</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420250.1">
        <property type="nucleotide sequence ID" value="XM_001420213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4D9"/>
    <dbReference type="STRING" id="436017.A4S4D9"/>
    <dbReference type="GeneID" id="5004449"/>
    <dbReference type="Gramene" id="ABO98543">
        <property type="protein sequence ID" value="ABO98543"/>
        <property type="gene ID" value="OSTLU_44053"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44053"/>
    <dbReference type="eggNOG" id="KOG2663">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032954_1_0_1"/>
    <dbReference type="OMA" id="VYPIEPS"/>
    <dbReference type="OrthoDB" id="2013116at2759"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1150:FF:000001">
        <property type="entry name" value="Acetolactate synthase small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="entry name" value="ACT-like. Chain A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054480">
        <property type="entry name" value="AHAS_small-like_ACT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008864">
        <property type="entry name" value="PRK11895.1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239:SF0">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22629">
        <property type="entry name" value="ACT_AHAS_ss"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="58"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="290"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="463" mass="50808" checksum="A8B81B49B797CC50" modified="2007-05-15" version="1">MTRSSATRGSGDDYDLDAGIAGATPGDGWTPTSYDGRGSTGDVYQGPARLAEGLRRHTVLVYVADETGMINRVAGVFARRGYNIESLAVGLNIDKAIFTISVICSDGDVGKLIKQVNKLAKVRKVENVTDKECVERGLMLLKVKCEPEQRSQVLEINRIFRASVVDVAERSLTMSVVGDPGKNRAFQSALMKFGVIQVARTGKLALKREPVYSEARSRRVKLMEAMRKAKDASAKYESILASRIVRAVAGMEHDDDGDLHVGDVYTSLENDEIGVWDVPMDENAKYTPHTISILVDNRPGVLDSITGVFARRGYNIQSLGVGPERTFDISRISTVVPGSTEDIAMLLKQILKVPYVISAEDITMTPFTERELMLIKVVSSRAQRAEIIDLCGMFRAKVCDISEDTVTIEVSGRQRKINAIQALLEPYGILEVARSGRVALPRDSGVDSKLMMAIESESDLDKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4G3</accession>
    <name>A4S4G3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cell division control protein 73 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PAFE3501</name>
        <name evidence="9" type="ORF">OSTLU_17261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC73 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420262.1">
        <property type="nucleotide sequence ID" value="XM_001420225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4G3"/>
    <dbReference type="STRING" id="436017.A4S4G3"/>
    <dbReference type="GeneID" id="5004330"/>
    <dbReference type="Gramene" id="ABO98555">
        <property type="protein sequence ID" value="ABO98555"/>
        <property type="gene ID" value="OSTLU_17261"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17261"/>
    <dbReference type="eggNOG" id="KOG3786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025849_0_1_1"/>
    <dbReference type="OMA" id="TECIDAN"/>
    <dbReference type="OrthoDB" id="2186602at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010228">
        <property type="term" value="P:vegetative to reproductive phase transition of meristem"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11990:FF:000002">
        <property type="entry name" value="protein CDC73 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11990">
        <property type="entry name" value="RNA polymerase II accessory factor, Cdc73 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007852">
        <property type="entry name" value="Cdc73/Parafibromin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031336">
        <property type="entry name" value="CDC73_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038103">
        <property type="entry name" value="CDC73_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032041">
        <property type="entry name" value="Cdc73_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466">
        <property type="entry name" value="CDC73 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466:SF8">
        <property type="entry name" value="PARAFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05179">
        <property type="entry name" value="CDC73_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16050">
        <property type="entry name" value="CDC73_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Paf1 complex subunit Cdc73 N-terminal" evidence="8">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Cell division control protein 73 C-terminal" evidence="7">
        <location>
            <begin position="279"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="50359" checksum="B84BEF80007B938F" modified="2007-05-15" version="1">MDPLRLIRDHTIAGIIAESTHDDERIHLKDVDVELRRTTETNYRSKAGNKLLKVEAIWYFIKYHVANPDAAHTAYMKAAIAAGFSTLSMLDRKDLIAYLTGERATSDRIDITVPVIVDEEGVSTVDAKRAREEDEAEGVPRERVLRDRNSVLRAPKDMTSVLDFFAAPEEEKERLEEEKQQAADLAKGIKNQRYRDVKEQVFWREHVGSDFDMMNLDTNASFLSGPKPPVDDGTDMLMTDARAMEKQPTAPSGPSTASRGGPAAAAKAPRKTSGKPGGVPIIIVPAGFNQKVVLNMFNAKEFLQDGKFTQWDVVQKGGAKKSSSVYISRTYKRDGAKVKYEVTEKAPHKRSEDWARVAAVFVLGAKWQFKDWPFRGVEDGDLVETFTKIRGFHARFDGDPEVDVVKTWNVKPITISRTKRHGDRAAFEFFWDELDRHLALRSSALKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4N1</accession>
    <name>A4S4N1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">THUMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420296.1">
        <property type="nucleotide sequence ID" value="XM_001420259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4N1"/>
    <dbReference type="GeneID" id="5004364"/>
    <dbReference type="Gramene" id="ABO98589">
        <property type="protein sequence ID" value="ABO98589"/>
        <property type="gene ID" value="OSTLU_26469"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26469"/>
    <dbReference type="HOGENOM" id="CLU_1013156_0_0_1"/>
    <dbReference type="OMA" id="WTKTAHT"/>
    <dbReference type="OrthoDB" id="495938at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11717">
        <property type="entry name" value="THUMP_THUMPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2300.10">
        <property type="entry name" value="THUMP superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040183">
        <property type="entry name" value="THUMPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452">
        <property type="entry name" value="THUMP DOMAIN CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452:SF10">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THUMP" evidence="1">
        <location>
            <begin position="136"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="28323" checksum="A887763DA4CCB2C2" modified="2007-05-15" version="1">MSVEHSRTVRLSEDLSYVQPTAPLPSWLKGFFVTAVSKGQDSVVQAAIEASNILNDYWFKVAYDAHRIDGEKPYERAEAMWIPGCDACAFVALRPDDNDANVYMCAKAIVEECRKGADWKQPTHVARIVAVEKSSSELELDALARDVLSKHFPERGGDSEPVTFGIHYEEHSPMRHFSSTDVNRFVGSHVPDEGYKVDLKNPRFTICVVNAGGSMMMSVVEAYDALGHFNVHRAAFEDKLSDTVPARGDDSAQPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Y0</accession>
    <name>A4S4Y0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_43956</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420512.1">
        <property type="nucleotide sequence ID" value="XM_001420475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Y0"/>
    <dbReference type="STRING" id="436017.A4S4Y0"/>
    <dbReference type="GeneID" id="5004527"/>
    <dbReference type="Gramene" id="ABO98805">
        <property type="protein sequence ID" value="ABO98805"/>
        <property type="gene ID" value="OSTLU_43956"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43956"/>
    <dbReference type="eggNOG" id="KOG0922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_5_11_1"/>
    <dbReference type="OMA" id="AVDICHT"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17978">
        <property type="entry name" value="DEXHc_DHX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000750">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF118">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="52"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="234"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO98805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="679" mass="75840" checksum="B6CADF6B866CC94D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Z3</accession>
    <name>A4S4Z3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420353.1">
        <property type="nucleotide sequence ID" value="XM_001420316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Z3"/>
    <dbReference type="GeneID" id="5004407"/>
    <dbReference type="Gramene" id="ABO98646">
        <property type="protein sequence ID" value="ABO98646"/>
        <property type="gene ID" value="OSTLU_17407"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17407"/>
    <dbReference type="HOGENOM" id="CLU_1247153_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="222" mass="25354" checksum="EC41FEA9B7CD9649" modified="2007-05-15" version="1">MSDGAMRPWFLRDEDRRRSLVYGVGAVAFALLGLVVTTGSRTEYKVVAYKPSLYEHVGSHQVKAHYDIYPDTHDIHQADHPSEDPADPEEELVYKYNGKHVSSANENRIRALYSPSGSSFIDVVKREGVDDATIFETCLYPTVTAEFRTYYGHDLTIEPDTTSKDLGKPVNQVEAHQFGCVWEKLLNKLAESNWKFVTSETIMTEKTFYEMHMITFSRKKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S556</accession>
    <name>A4S556_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine diphosphorylase</fullName>
            <ecNumber evidence="3">2.7.7.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26644</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="3"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420384.1">
        <property type="nucleotide sequence ID" value="XM_001420347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S556"/>
    <dbReference type="STRING" id="436017.A4S556"/>
    <dbReference type="GeneID" id="5004289"/>
    <dbReference type="Gramene" id="ABO98677">
        <property type="protein sequence ID" value="ABO98677"/>
        <property type="gene ID" value="OSTLU_26644"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26644"/>
    <dbReference type="eggNOG" id="KOG2388">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025603_1_1_1"/>
    <dbReference type="OMA" id="YFQVDNP"/>
    <dbReference type="OrthoDB" id="532420at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04193">
        <property type="entry name" value="UDPGlcNAc_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF2">
        <property type="entry name" value="LD24639P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="487" mass="52548" checksum="50DBAD407F1186F3" modified="2007-05-15" version="1">MGCASSKSSSLTLARARYASLPGPEQKTIVGALERAATSDADAARLCAALANVECERAVDVFQRSALAHETSTSGTLEPVRCDCEIVPGSDDAERWRRRGLECVKRGKLAVVLLAGGQGTRLGSANPKGMYDIGLPSKKTLFELQGERLAKLGALAGARAPTWYVMTSPFTHDATVAFFKSRDYFGLNARDVVFFKQGTLPCFTEDGEIILKSFGEVSEAPDGNGGIYAAMAREGVIADMRKRKIEHVYAYCVDNALVQVGDPTFVGCCVERECEAGAKVIAKAYPTEPVGVFACRKNEATGAKEYHVVEYSEIPESLATAKDKKTGELKFNAANIALHYFSFDFLSRCCLDIALPHHVARKKIPYLDVNTGKTIEPSSPNGIKLEAFIFDTYKYAKSVCVVRGDRALDFAPVKNAEGAGKDSPDTAREAILSLHARWILQAGGVIVDENDVPVPTDRARCEVSPAVSYAGESLASRLRVRVGGVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="107" xmlns="https://uniprot.org/uniprot">
    <accession>A4S584</accession>
    <name>A4S584_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone-binding protein RBBP4-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_26671</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420563.1">
        <property type="nucleotide sequence ID" value="XM_001420526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S584"/>
    <dbReference type="STRING" id="436017.A4S584"/>
    <dbReference type="GeneID" id="5004747"/>
    <dbReference type="Gramene" id="ABO98856">
        <property type="protein sequence ID" value="ABO98856"/>
        <property type="gene ID" value="OSTLU_26671"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26671"/>
    <dbReference type="eggNOG" id="KOG0264">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020445_3_1_1"/>
    <dbReference type="OMA" id="KIRAMPA"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005677">
        <property type="term" value="C:chromatin silencing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070176">
        <property type="term" value="C:DRM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001222">
        <property type="term" value="F:transcription corepressor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070828">
        <property type="term" value="P:heterochromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048366">
        <property type="term" value="P:leaf development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045787">
        <property type="term" value="P:positive regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010026">
        <property type="term" value="P:trichome differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000512">
        <property type="entry name" value="WD-40 repeat-containing protein MSI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="9">
        <location>
            <begin position="33"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="237"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="283"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="327"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="432" mass="47767" checksum="C41A28902900569D" modified="2007-05-15" version="1">MGADDDATHAHAAGGNRDHDDAPDEAAERLVSEEYKIWKKNTPFLYDLVVTHALEWPSLTVQWLPDRVEHPDKDYASQKLILGTHTSEHEQNYLMIAEAQLPLESAEVDGREYDDESGEAGGFGSGGAKVKVVQHINHDGEVNRARYMPQNSFVLATKTVSADVYVFDYTKHPSKADADSGCQPNIRLKGHLTEGYGLSWSPFKSGHLLSGSDDAQICLWDVTGGDGARELDAQTIYKGHLSVVEDVAWHAKHEHMFGSVGDDKHLILWDTRAVPASAAVLDIEAHDAEVNCLSFNPYNETLLATGSADKTVNLFDIRNTKKPLHTFEHHTEEVFQIGWSPKSETVLASCGADRRMMIWDLSKIGDEQSPEDAEDGPPELLFIHGGHTSKISDFSWNQNDDWVIASVAEDNILQIWQPNANCVNAGGDDDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5A4</accession>
    <name>A4S5A4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">6-phosphogluconate dehydrogenase NADP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_50994</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420571.1">
        <property type="nucleotide sequence ID" value="XM_001420534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5A4"/>
    <dbReference type="STRING" id="436017.A4S5A4"/>
    <dbReference type="GeneID" id="5004810"/>
    <dbReference type="Gramene" id="ABO98864">
        <property type="protein sequence ID" value="ABO98864"/>
        <property type="gene ID" value="OSTLU_50994"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50994"/>
    <dbReference type="eggNOG" id="KOG0409">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_0_0_1"/>
    <dbReference type="OMA" id="ENHGQRM"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF2">
        <property type="entry name" value="CYTOKINE-LIKE NUCLEAR FACTOR N-PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="5">
        <location>
            <begin position="15"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="6">
        <location>
            <begin position="195"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="33396" checksum="C088FA8811F0AE8B" modified="2007-05-15" version="1">MRRRGASTAARGAAVGFIGMGIMGAAMSRALARAGARVVAWNRSRDKAEATRAAFERDDAEAMRANGGAIDVVDAVADVAARCEVTFAMLADPRAALEVARAYAAASGTRDGDARTYVDCSTVDGACGEATREILGENVRFLAAPVSGGWRDAAKGELLFLGGGDARAYEDGARFMDVMGAKRWLVGDSPTHAARAKLMLQIMMGNVVGALGEMHALSERAGLDSNAILEMLSHSAMGSPLTTAKGKLMADRNFAPNFQVYLQQKDLRLALNLADELDFAAPITAATNAQYLKAKSLGHANSDFAAVAAAYTGEKPDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Y0</accession>
    <name>A4S5Y0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_39438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate acid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420689.1">
        <property type="nucleotide sequence ID" value="XM_001420652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Y0"/>
    <dbReference type="STRING" id="436017.A4S5Y0"/>
    <dbReference type="GeneID" id="5004708"/>
    <dbReference type="Gramene" id="ABO98982">
        <property type="protein sequence ID" value="ABO98982"/>
        <property type="gene ID" value="OSTLU_39438"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39438"/>
    <dbReference type="eggNOG" id="ENOG502QVAJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077795_2_2_1"/>
    <dbReference type="OMA" id="PEVDLMP"/>
    <dbReference type="OrthoDB" id="1476984at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246:SF1">
        <property type="entry name" value="2-DEHYDRO-3-DEOXY-6-PHOSPHOGALACTONATE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="214" mass="22447" checksum="91CF7FF00A56D1FC" modified="2007-05-15" version="1">MRTDAEFNEVLDQFAKHKACAVLRTGVEGAAYNAMDAAVQGGFKLVEFTLTTPGCLDAVSRFASRTDVLTGCGTILNIDDAKRALDAGSKFIVAPILIPEVVEWCAANKIVCIPGCQTPSELYRAYSLGAPVQKLFPGVAGGPNWVRAVASALPMLRINPTSGVEIDTAADYLRAGAASLGFVAPAFDQNAIKAGDWDAISKRATEIIAAVKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6B6</accession>
    <name>A4S6B6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Eukaryotic elongation factor 1 alpha</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Eukaryotic translation elongation factor 1 alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">EF1A1</name>
        <name evidence="9" type="synonym">EF1A2</name>
        <name evidence="7" type="synonym">EF1A3</name>
        <name evidence="8" type="ORF">OSTLU_27060</name>
        <name evidence="7" type="ORF">OSTLU_27198</name>
        <name evidence="9" type="ORF">OSTLU_29711</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420985.1">
        <property type="nucleotide sequence ID" value="XM_001420948.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421065.1">
        <property type="nucleotide sequence ID" value="XM_001421028.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422909.1">
        <property type="nucleotide sequence ID" value="XM_001422872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6B6"/>
    <dbReference type="STRING" id="436017.A4S6B6"/>
    <dbReference type="GeneID" id="5004985"/>
    <dbReference type="GeneID" id="5005121"/>
    <dbReference type="GeneID" id="5006884"/>
    <dbReference type="Gramene" id="ABO99278">
        <property type="protein sequence ID" value="ABO99278"/>
        <property type="gene ID" value="OSTLU_27198"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99358">
        <property type="protein sequence ID" value="ABO99358"/>
        <property type="gene ID" value="OSTLU_27060"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01268">
        <property type="protein sequence ID" value="ABP01268"/>
        <property type="gene ID" value="OSTLU_29711"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27060"/>
    <dbReference type="KEGG" id="olu:OSTLU_27198"/>
    <dbReference type="KEGG" id="olu:OSTLU_29711"/>
    <dbReference type="eggNOG" id="KOG0052">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_3_5_1"/>
    <dbReference type="OMA" id="AIRDMGM"/>
    <dbReference type="OrthoDB" id="494139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000115">
        <property type="entry name" value="Eukaryotic translation elongation factor 1 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002868">
        <property type="entry name" value="Eukaryotic translation elongation factor 1 alpha 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000159">
        <property type="entry name" value="Translation elongation factor alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="5"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="467" mass="51450" checksum="5DCE7ADA990C7661" modified="2007-05-15" version="1">MSEGKEHLSIVICGHVDSGKSTTTGRLLFELGGIPERELEKLRAEADALGKSSFAFAFYMDRQKEERERGVTISCTTKEFFTDKWHYTIIDAPGHRDFIKNMISGAAQADVALLMVPADGNFTVAIQKGNHKAGEVQGQTRQHARLLNLLGVKQLICGINKMDCDMAGYKQERYEEIRNEMKNMLIKVGWKKDYVEKSVPVLPISGWNGDNLLSKSAKMPWWNGVDVEDYMGGGKKFHIDCLLNVLNDMVDKPDRNTEAAMRLPISGVYKIKGVGDVLAGRVEQGLVKPGEDVVFLPTHTSSNPCGGKVFTVEMHHKRVEAAAPGDNVGMNIKGLDKLNMPRTGDVMIYKKDTSLAPCKEFTAQIQTLDIPGELKAGYSPIGFVRCGRSACKLTALNFKVGKETGGKKLESPMSLKSNEVAECVFEPVHPLVVDSFKKCEGLSRIAFLDGNTAVMLGKITKVEYKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6H7</accession>
    <name>A4S6H7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420945.1">
        <property type="nucleotide sequence ID" value="XM_001420908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6H7"/>
    <dbReference type="STRING" id="436017.A4S6H7"/>
    <dbReference type="GeneID" id="5004952"/>
    <dbReference type="Gramene" id="ABO99238">
        <property type="protein sequence ID" value="ABO99238"/>
        <property type="gene ID" value="OSTLU_27124"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27124"/>
    <dbReference type="eggNOG" id="KOG3250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1449925_0_0_1"/>
    <dbReference type="OMA" id="ANTEHEP"/>
    <dbReference type="OrthoDB" id="10265275at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0736">Signalosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="23812" checksum="31E5AA703352A697" modified="2007-05-15" version="1">MRVTKILHAMERTEGFECAAEVRAMVEIFAHGTLREYRARAANEKLPTLTTREEAKLKRLSTCALCAEGGTIAYVRLMRELEFTSERAMEKFIVDECLGEIVWGRLDPKNKVLRVRRAKARDARASALDGVIADVSRWHAITETMLASLNEQIAYVSSEKAESLAREDELNAAIEETKKQLKAAEPDVAERVDEDEDMDEDGPSTGVKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7P9</accession>
    <name>A4S7P9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small VCP/p97-interacting protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421493.1">
        <property type="nucleotide sequence ID" value="XM_001421456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7P9"/>
    <dbReference type="GeneID" id="5005467"/>
    <dbReference type="Gramene" id="ABO99786">
        <property type="protein sequence ID" value="ABO99786"/>
        <property type="gene ID" value="OSTLU_27575"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27575"/>
    <dbReference type="HOGENOM" id="CLU_2658959_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031632">
        <property type="entry name" value="SVIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15811">
        <property type="entry name" value="SVIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0519">Myristate</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8133" checksum="D11ABDDAC2A4BADD" modified="2007-05-15" version="1">MGCCASAPYDDLATVDERRAMALKAAEARNKQSEMRGIKSEAMASKVRASKAAAARTSGDAHGDRKSEQMARDWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7X9</accession>
    <name>A4S7X9_OSTLU</name>
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        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HMGB3503</name>
        <name evidence="5" type="ORF">OSTLU_25566</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421528.1">
        <property type="nucleotide sequence ID" value="XM_001421491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7X9"/>
    <dbReference type="STRING" id="436017.A4S7X9"/>
    <dbReference type="GeneID" id="5005246"/>
    <dbReference type="Gramene" id="ABO99821">
        <property type="protein sequence ID" value="ABO99821"/>
        <property type="gene ID" value="OSTLU_25566"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25566"/>
    <dbReference type="eggNOG" id="KOG0381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_822298_0_0_1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="120"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="120"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="338" mass="38925" checksum="5DFA5CB71FD5F3E2" modified="2007-05-15" version="1">MVTVGMQTLEKKPRKKRRDKDKPKRAMSAYLVFLNKHRDATQKKNPSWSVTDVTKELAGKWKTVTQSERDECQRVSDEDKARYYREMQNYVPLPDEKEEPPLRFDKDGNRKRRKKDKNAPRKNRSSYIIWAQEYRDKTFRPKANTPDAVSFRDQAAQLGAAWKACTPQQRKKYDDMAEKEAQAYAIKRDAYKAEQKAIALAAREAKRQRLLDEKRAWEATKIAAAQLKEDKKKEKSAQLSPGKARPFGGPSSKAVPKKVVHKEADNVTMAKMRSAVLAVAPSDNAWRAVQDVYGSAPDKVMEAFRNFVDNRKMTNFVPDHRAFMNAVLGYDMAATFMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8C1</accession>
    <name>A4S8C1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_7707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421596.1">
        <property type="nucleotide sequence ID" value="XM_001421559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8C1"/>
    <dbReference type="STRING" id="436017.A4S8C1"/>
    <dbReference type="GeneID" id="5005634"/>
    <dbReference type="Gramene" id="ABO99889">
        <property type="protein sequence ID" value="ABO99889"/>
        <property type="gene ID" value="OSTLU_7707"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7707"/>
    <dbReference type="eggNOG" id="ENOG502RXIW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065901_1_2_1"/>
    <dbReference type="OMA" id="NWRRAQI"/>
    <dbReference type="OrthoDB" id="3543at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051266">
        <property type="term" value="F:sirohydrochlorin ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03416">
        <property type="entry name" value="CbiX_SirB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050963">
        <property type="entry name" value="Sirohydro_Cobaltochel/CbiX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33542">
        <property type="entry name" value="SIROHYDROCHLORIN FERROCHELATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33542:SF3">
        <property type="entry name" value="SIROHYDROCHLORIN FERROCHELATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="134" mass="14297" checksum="B6C78CCA0F42110C" modified="2007-05-15" version="1" fragment="single">GVVVVDHGSRRAASNEQLERFAALYATATGRAVVEPAHMELAPPTIADAFERCVERGANVVVVAPFFLSPGRHWQEDIPRLVDEAAAAHPGVKYLISAPIGLHPLMAEVIDSRLRHCLAHVNEGGPECDVCAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8G6</accession>
    <name>A4S8G6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421617.1">
        <property type="nucleotide sequence ID" value="XM_001421580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8G6"/>
    <dbReference type="STRING" id="436017.A4S8G6"/>
    <dbReference type="GeneID" id="5005702"/>
    <dbReference type="Gramene" id="ABO99910">
        <property type="protein sequence ID" value="ABO99910"/>
        <property type="gene ID" value="OSTLU_27845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27845"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007931_2_1_1"/>
    <dbReference type="OMA" id="IAANKYH"/>
    <dbReference type="OrthoDB" id="509488at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="510"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="536" mass="58905" checksum="C666BD99FE24F851" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8I3</accession>
    <name>A4S8I3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">R-spondin Fu-CRD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_27861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421772.1">
        <property type="nucleotide sequence ID" value="XM_001421735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8I3"/>
    <dbReference type="GeneID" id="5005709"/>
    <dbReference type="Gramene" id="ABP00066">
        <property type="protein sequence ID" value="ABP00066"/>
        <property type="gene ID" value="OSTLU_27861"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27861"/>
    <dbReference type="HOGENOM" id="CLU_412999_0_0_1"/>
    <dbReference type="OrthoDB" id="300641at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00064">
        <property type="entry name" value="FU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.220.10">
        <property type="entry name" value="Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006212">
        <property type="entry name" value="Furin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043601">
        <property type="entry name" value="Rspo_Fu-CRD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15913">
        <property type="entry name" value="Furin-like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00261">
        <property type="entry name" value="FU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673244" description="R-spondin Fu-CRD domain-containing protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="R-spondin Fu-CRD" evidence="6">
        <location>
            <begin position="344"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="665" mass="71636" checksum="45B48AE9D10F0756" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Q1</accession>
    <name>A4S8Q1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-ketoglutarate-dependent dioxygenase AlkB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_7494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421667.1">
        <property type="nucleotide sequence ID" value="XM_001421630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Q1"/>
    <dbReference type="STRING" id="436017.A4S8Q1"/>
    <dbReference type="GeneID" id="5005777"/>
    <dbReference type="Gramene" id="ABO99960">
        <property type="protein sequence ID" value="ABO99960"/>
        <property type="gene ID" value="OSTLU_7494"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7494"/>
    <dbReference type="eggNOG" id="KOG3200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1329320_0_0_1"/>
    <dbReference type="OMA" id="IFKLWPR"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032862">
        <property type="entry name" value="ALKBH6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="6">
        <location>
            <begin position="56"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="22981" checksum="E5BBD04CDA4D3362" modified="2007-05-15" version="1" fragment="single">PGLAYCREFIGARDAEFVESALLREPAAWWTKGRGRRVMNAGGTSPSRLYREGDDEAIPTYLRELVEVLVRRKASERAANHVLVNEYDADGFISPHSDGDVYAPDVQILTLRSSALIEFWPAEGATAGDFDECDNIDAPRPVVSVLLEPRSLLMYRGEAYRLRHGIRARVKDVVAAETANARELGLEIGDVVERNPAGRLSVVFVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8T5</accession>
    <name>A4S8T5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_18446</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="6"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421947.1">
        <property type="nucleotide sequence ID" value="XM_001421910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8T5"/>
    <dbReference type="STRING" id="436017.A4S8T5"/>
    <dbReference type="GeneID" id="5005990"/>
    <dbReference type="Gramene" id="ABP00241">
        <property type="protein sequence ID" value="ABP00241"/>
        <property type="gene ID" value="OSTLU_18446"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18446"/>
    <dbReference type="eggNOG" id="KOG2872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040933_0_2_1"/>
    <dbReference type="OMA" id="CAGQRGH"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046686">
        <property type="term" value="P:response to cadmium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000006">
        <property type="entry name" value="Uroporphyrinogen decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF167">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="11">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="321" mass="35783" checksum="7096C8C3353B2AF4" modified="2007-05-15" version="1">MMRQAGRYMKEYRDVAVKHPSFRERSETTDLICEITLQPFRAFQPDGVILFSDILTPFPAFGIDFEIDDYKGPMLEKTIRSAEDLKMLHEVDLSKVEFVADSLKILRQEVGDEAAVLGFVGAPWTLCTYIVEGQSTSTYKTIKSMCFNNPEVLHKLLSAVADALAVYVGFQIDAGAQVIQVFDSWGGQLPPHMWEEWSKPYIERVVRKVNQTHPGVPITMYANGSGGLLERMATLPVDTIGLDWTIDMEDGRRRVGDKAVQGNVDPVVLFAGEDAIEKAVRDVCRKAGPTGHILNLGHGVLVGTPEESVKHFFDVSKTITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S920</accession>
    <name>A4S920_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Complex I assembly factor TIMMDC1, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translocase of inner mitochondrial membrane domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_93853</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421857.1">
        <property type="nucleotide sequence ID" value="XM_001421820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S920"/>
    <dbReference type="STRING" id="436017.A4S920"/>
    <dbReference type="GeneID" id="5005886"/>
    <dbReference type="Gramene" id="ABP00151">
        <property type="protein sequence ID" value="ABP00151"/>
        <property type="gene ID" value="OSTLU_93853"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93853"/>
    <dbReference type="eggNOG" id="KOG4608">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1295922_0_0_1"/>
    <dbReference type="OMA" id="WIQLKLI"/>
    <dbReference type="OrthoDB" id="497911at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055299">
        <property type="entry name" value="TIMMDC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13002">
        <property type="entry name" value="C3ORF1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13002:SF1">
        <property type="entry name" value="COMPLEX I ASSEMBLY FACTOR TIMMDC1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="209" mass="23118" checksum="21CD085029AF80CB" modified="2007-05-15" version="1">MERAFERIKPGEDPPPPPPELLQWARETTYGLCGGIVYGAASAHYAERRRVVDAMESATKRKHRIWTRTISDVTLHGMRLGSFVSVFSAARLGLEKRRDARDMWNVVGAGMLTSALTGMAIPGGVAVRARGAALGVVVGGAATLPFGYAMQELEKLVPELVAPAAAAAMSEGESRKLDVTEMFIEQVEAELEEYRREERKRRRGWFWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S964</accession>
    <name>A4S964_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPS2</name>
        <name evidence="10" type="ORF">OSTLU_18532</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 11">CCE9901</strain>
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        <text evidence="1 7">Belongs to the universal ribosomal protein uS5 family.</text>
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        <property type="protein sequence ID" value="ABP00176"/>
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    </dbReference>
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    <dbReference type="eggNOG" id="KOG0877">
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    <dbReference type="HOGENOM" id="CLU_065898_0_2_1"/>
    <dbReference type="OMA" id="PYEEWSD"/>
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    <dbReference type="Proteomes" id="UP000001568">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
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    </dbReference>
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        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="92"/>
            <end position="155"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
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            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="29851" checksum="E9EDC25EB7350BA0" modified="2007-05-15" version="1">MSDRGGFSRGFGRGGERGRGDRGRGDRGRGDRGRGRGRGRGRGGDDKDVWVPCTKLGRLVQQGKIKSLEHIFLFSLPIKEHQIVEHFIGGELKDEVMKICPVQKQTTAGQRMRFKAFVVVGDCNGHIGLGVKACKEVAHSIQGSMILAKLNIVPVRRGYWGSKLGEPHTIPTKVHGKCGSVHVRLIPAPRGAGIVASGTVKKVLAMAGLHDVYTCSRGHTRTLGNSVKATYEALKNSYGFLTPDLWAETRFAKPPAQEFTDLLSKPDRKARDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
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    <name>A4S9J2_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422040.1"/>
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        <property type="protein sequence ID" value="ABP00394"/>
        <property type="gene ID" value="OSTLU_28220"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28220"/>
    <dbReference type="HOGENOM" id="CLU_1470525_0_0_1"/>
    <dbReference type="OMA" id="NTSATWE"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="20410" checksum="673B5D0019B1BD53" modified="2007-05-15" version="1">MTTNDPNVVNGDNGVYDEDMTLNARCQSWLLTGTPSASSSNASYHSINTSATWEQTMSWCPCSKWPCTCDGCGCYVEGCDEAWRRTQAGAGARYEPAIGMLWGVFALLITCFGLVVIWLKSQQRTEARREAYLRSIVDMTPKDEKFKELYRDMAPPEGTYVVHSPGRGAAHIAIAVREKHSAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9L4</accession>
    <name>A4S9L4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9L4"/>
    <dbReference type="STRING" id="436017.A4S9L4"/>
    <dbReference type="GeneID" id="5006146"/>
    <dbReference type="Gramene" id="ABP00508">
        <property type="protein sequence ID" value="ABP00508"/>
        <property type="gene ID" value="OSTLU_25714"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25714"/>
    <dbReference type="HOGENOM" id="CLU_424175_0_0_1"/>
    <dbReference type="OMA" id="GCRFCRV"/>
    <dbReference type="OrthoDB" id="10615382at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672263" evidence="2">
        <location>
            <begin position="21"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="646" mass="67452" checksum="B0FD58B11EE56CC6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA25</accession>
    <name>A4SA25_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_42057</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422167.1">
        <property type="nucleotide sequence ID" value="XM_001422130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA25"/>
    <dbReference type="STRING" id="436017.A4SA25"/>
    <dbReference type="GeneID" id="5006330"/>
    <dbReference type="Gramene" id="ABP00484">
        <property type="protein sequence ID" value="ABP00484"/>
        <property type="gene ID" value="OSTLU_42057"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42057"/>
    <dbReference type="eggNOG" id="KOG2493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_3_1_1"/>
    <dbReference type="OMA" id="ITWVGYK"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF96">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="538" mass="57501" checksum="03C67FDFD3B3EBED" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAD5</accession>
    <name>A4SAD5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_18855</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxin-11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422416.1">
        <property type="nucleotide sequence ID" value="XM_001422379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAD5"/>
    <dbReference type="STRING" id="436017.A4SAD5"/>
    <dbReference type="GeneID" id="5006426"/>
    <dbReference type="Gramene" id="ABP00733">
        <property type="protein sequence ID" value="ABP00733"/>
        <property type="gene ID" value="OSTLU_18855"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18855"/>
    <dbReference type="eggNOG" id="KOG4186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_981374_0_0_1"/>
    <dbReference type="OrthoDB" id="411017at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044375">
        <property type="term" value="P:regulation of peroxisome size"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="30324" checksum="0459B1CA8F9FC3EB" modified="2007-05-15" version="1">MTTGRKAPAPGATRATTRATTREDALDRALRALALAKSFLSSYDARDKTLAFAQYATLCASNGAPGKLTSASASIGMSRKPFRIVKPLESAATAARKRASDAPTSAAETIRALGMTCYFAFDHLVWACASGACGTGKEDARGRFQRLSYWGWFFGSASGLFLDTNELNALLDVMREKGFGEDGNAPKTRDGENTSPFVDADEDLDADEREAREREVEALRKRARKVFVGLITNSAQAILALALLEKVKMSKRKIGALGMFLSAVNIASMLPAPAAEAPGKTKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAL8</accession>
    <name>A4SAL8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCAAT-binding factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_25819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422454.1">
        <property type="nucleotide sequence ID" value="XM_001422417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAL8"/>
    <dbReference type="STRING" id="436017.A4SAL8"/>
    <dbReference type="GeneID" id="5006512"/>
    <dbReference type="Gramene" id="ABP00771">
        <property type="protein sequence ID" value="ABP00771"/>
        <property type="gene ID" value="OSTLU_25819"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25819"/>
    <dbReference type="eggNOG" id="KOG2038">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003417_1_0_1"/>
    <dbReference type="OMA" id="EIWCNDE"/>
    <dbReference type="OrthoDB" id="28947at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040155">
        <property type="entry name" value="CEBPZ/Mak21-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048">
        <property type="entry name" value="CCAAT-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048:SF0">
        <property type="entry name" value="CCAAT_ENHANCER-BINDING PROTEIN ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="577"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="474"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="678"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="883"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1058"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="709"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="893"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="916"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1071"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1130" mass="124070" checksum="D4602368F0FB0E9D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAM5</accession>
    <name>A4SAM5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Geranylgeranyl transferase type-2 subunit alpha</fullName>
            <ecNumber evidence="2 9">2.5.1.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Geranylgeranyl transferase type II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_43543</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="2 9"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422636.1">
        <property type="nucleotide sequence ID" value="XM_001422599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAM5"/>
    <dbReference type="STRING" id="436017.A4SAM5"/>
    <dbReference type="GeneID" id="5006517"/>
    <dbReference type="Gramene" id="ABP00953">
        <property type="protein sequence ID" value="ABP00953"/>
        <property type="gene ID" value="OSTLU_43543"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43543"/>
    <dbReference type="eggNOG" id="KOG0529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026582_1_0_1"/>
    <dbReference type="OrthoDB" id="1658at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097354">
        <property type="term" value="P:prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.120:FF:000035">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF2">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP00953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="271" mass="31541" checksum="EDFC89070B16B4E7" modified="2007-05-15" version="1">MKACEKLLGLCPEILTAWNYRRETIEARTGDAATTSEGGDEGEGEGEGDWWSDELRVSETALRNNPKSYPSWYHRKWVLRRMIEAFGTEEGKARETLEREAKLCADMLNADDRNFHCWAYRRFVAEKLGRGVDEELQYTLTKIENNFSNYSAWHYRSAILESRGAADAETLEREFELASNAFYTEPEDQSAWMYHRWLTSRARAIEDAKDRESLLERERQTCREVSDLEPTCKWPLLALASLGDEHPREMFQNLAALDPARGGYYRERRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAW4</accession>
    <name>A4SAW4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CHR3518</name>
        <name evidence="8" type="ORF">OSTLU_18985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422675.1">
        <property type="nucleotide sequence ID" value="XM_001422638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAW4"/>
    <dbReference type="STRING" id="436017.A4SAW4"/>
    <dbReference type="GeneID" id="5006567"/>
    <dbReference type="Gramene" id="ABP00992">
        <property type="protein sequence ID" value="ABP00992"/>
        <property type="gene ID" value="OSTLU_18985"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18985"/>
    <dbReference type="eggNOG" id="KOG1000">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_33_4_1"/>
    <dbReference type="OMA" id="FTLHRAR"/>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18010">
        <property type="entry name" value="DEXHc_HARP_SMARCAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF3">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="166"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="434"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="580"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="580"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="638" mass="69560" checksum="91BFBB6D9CDCB01F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB66</accession>
    <name>A4SB66_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422723.1">
        <property type="nucleotide sequence ID" value="XM_001422686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB66"/>
    <dbReference type="GeneID" id="5006780"/>
    <dbReference type="Gramene" id="ABP01040">
        <property type="protein sequence ID" value="ABP01040"/>
        <property type="gene ID" value="OSTLU_94090"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94090"/>
    <dbReference type="HOGENOM" id="CLU_2216724_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11746" checksum="69AC866FA07A4D2C" modified="2007-05-15" version="1" fragment="single">VTDDARAMPRWRTQDEELPANSEELQQAIKDWLTKKRTAAGKVKQVLGLLNHERLGYVCAQCAVATRGGREVEGDDGEVLSRSRRANGPTDRATRAFHPSQGGCGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB94</accession>
    <name>A4SB94_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_94099</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422735.1">
        <property type="nucleotide sequence ID" value="XM_001422698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB94"/>
    <dbReference type="STRING" id="436017.A4SB94"/>
    <dbReference type="GeneID" id="5006637"/>
    <dbReference type="Gramene" id="ABP01052">
        <property type="protein sequence ID" value="ABP01052"/>
        <property type="gene ID" value="OSTLU_94099"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94099"/>
    <dbReference type="eggNOG" id="ENOG502QSRR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_322985_0_0_1"/>
    <dbReference type="OMA" id="RMDASNH"/>
    <dbReference type="OrthoDB" id="103454at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037624">
        <property type="entry name" value="Nup133-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405:SF11">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="442"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP01052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="975" mass="105318" checksum="990716923E4EB92F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBD9</accession>
    <name>A4SBD9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <shortName evidence="4">HIB-CoA hydrolase</shortName>
            <shortName evidence="4">HIBYL-CoA-H</shortName>
            <ecNumber evidence="2 4">3.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">3-hydroxyisobutyryl-coenzyme A hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_4293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="2 4"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422759.1">
        <property type="nucleotide sequence ID" value="XM_001422722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBD9"/>
    <dbReference type="STRING" id="436017.A4SBD9"/>
    <dbReference type="GeneID" id="5006658"/>
    <dbReference type="Gramene" id="ABP01076">
        <property type="protein sequence ID" value="ABP01076"/>
        <property type="gene ID" value="OSTLU_4293"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4293"/>
    <dbReference type="eggNOG" id="KOG1684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_22_1_1"/>
    <dbReference type="OMA" id="YRIACHV"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU369070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP01076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="35752" checksum="13156093C5B18A32" modified="2007-05-15" version="1" fragment="single">VTIDRPRALNALNRDAVERLHELFQRAERDDAAACYLLRGHGSRAFCAGGDVRAVREMVVRGDVDGAIAFFDREFALNAALHALRKPSACVWNGVVMGGGAGLSCYCPVRVATDATVFAMPECAIGLYPDVGAGWFLNALCGHAYATCLSLTGARVRGIDCKRIGLATHYVTMEVWDRETEKRVNALERGASVEDLARAAASGERDEPAATSYLTSERGRAMIDEVFGNDAMSLDDITREIARKEDAAESEAERAFFAECRESVAKASPTSLGVSLELMRRSRGKSLEWVLAMDNALIVKFIHAPDFRRGVEAVLIDKVGAPPPGGWMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBF2</accession>
    <name>A4SBF2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HMGB3506</name>
        <name evidence="7" type="ORF">OSTLU_19125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422765.1">
        <property type="nucleotide sequence ID" value="XM_001422728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBF2"/>
    <dbReference type="STRING" id="436017.A4SBF2"/>
    <dbReference type="GeneID" id="5006822"/>
    <dbReference type="Gramene" id="ABP01082">
        <property type="protein sequence ID" value="ABP01082"/>
        <property type="gene ID" value="OSTLU_19125"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19125"/>
    <dbReference type="HOGENOM" id="CLU_501955_0_0_1"/>
    <dbReference type="OrthoDB" id="550908at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="465"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="465"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="437"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="58"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="146"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP01082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="543" mass="61608" checksum="682C7CE201B6A056" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBG2</accession>
    <name>A4SBG2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422610.1">
        <property type="nucleotide sequence ID" value="XM_001422573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBG2"/>
    <dbReference type="STRING" id="436017.A4SBG2"/>
    <dbReference type="GeneID" id="5006829"/>
    <dbReference type="Gramene" id="ABP00927">
        <property type="protein sequence ID" value="ABP00927"/>
        <property type="gene ID" value="OSTLU_94122"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94122"/>
    <dbReference type="eggNOG" id="KOG1967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005943_0_0_1"/>
    <dbReference type="OMA" id="DCCERNA"/>
    <dbReference type="OrthoDB" id="553056at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="2">
        <location>
            <begin position="62"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1083" mass="113852" checksum="30CB76FBFA762C0A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQQ7</accession>
    <name>A4RQQ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U2A'/phosphoprotein 32 family A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_28748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415777.1">
        <property type="nucleotide sequence ID" value="XM_001415740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQQ7"/>
    <dbReference type="STRING" id="436017.A4RQQ7"/>
    <dbReference type="GeneID" id="4999405"/>
    <dbReference type="Gramene" id="ABO94069">
        <property type="protein sequence ID" value="ABO94069"/>
        <property type="gene ID" value="OSTLU_28748"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28748"/>
    <dbReference type="eggNOG" id="KOG0531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_317705_0_0_1"/>
    <dbReference type="OMA" id="MRCARIR"/>
    <dbReference type="OrthoDB" id="1517790at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003603">
        <property type="entry name" value="U2A'_phosphoprotein32A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00446">
        <property type="entry name" value="LRRcap"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="U2A'/phosphoprotein 32 family A C-terminal" evidence="4">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="U2A'/phosphoprotein 32 family A C-terminal" evidence="4">
        <location>
            <begin position="657"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="U2A'/phosphoprotein 32 family A C-terminal" evidence="4">
        <location>
            <begin position="910"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="935" mass="106004" checksum="BEE4BDD0BD8218D2" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQY1</accession>
    <name>A4RQY1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein axonemal intermediate chain 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">WD repeat-containing protein 78</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_28823</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Dynein axonemal particle</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415469.1">
        <property type="nucleotide sequence ID" value="XM_001415432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQY1"/>
    <dbReference type="STRING" id="436017.A4RQY1"/>
    <dbReference type="GeneID" id="4999937"/>
    <dbReference type="Gramene" id="ABO93761">
        <property type="protein sequence ID" value="ABO93761"/>
        <property type="gene ID" value="OSTLU_28823"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28823"/>
    <dbReference type="eggNOG" id="KOG1587">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047897_0_0_1"/>
    <dbReference type="OMA" id="WCATEFA"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120293">
        <property type="term" value="C:dynein axonemal particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF12">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO93761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="459" mass="50468" checksum="C2689A38B2CEDFF9" modified="2007-05-15" version="1">MESALRERERLEYCLKYRGLRPSDDDASALSALTILTCEQTRGMNVSSVKLNPVWGDLVCVAYGEFSFAGANRETREKGALAFWSIRSEAPLCVLRLESGVMSIDWSRRDPNLLAVGCYDGEVFVYDVGEFVSRDGSATTSDSTTMTTTTRRGQITSSEQRHSDPVWAVTWVAVKATDGFEDEENVDTVTALVSASTDGKVMRWDLRDGLYGTEVLAVRWSPPGVENDGAVSSKASETRGGDLVQHSGVMCLDFSSDAKYYVVGTEEGKIHKCSLSYSDQYLASYASHVGPVYAIKFNPFHERVFVTCSADWTVRVFLDDTQRDDDAFASIDEASSRLKASSLIQPRVVIEYSQQPINAVDWSPWCATEFALVTDAGTIEIWDLASSSVVPKHELSITDDKTAAVSVTYAHDAPVILVGCASGSTHVLRMKWRDPTEGIAAKETQRERLEEVLGTSIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR03</accession>
    <name>A4RR03_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="3 13">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_28845</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="3 13"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415482.1">
        <property type="nucleotide sequence ID" value="XM_001415445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR03"/>
    <dbReference type="STRING" id="436017.A4RR03"/>
    <dbReference type="GeneID" id="4999430"/>
    <dbReference type="Gramene" id="ABO93774">
        <property type="protein sequence ID" value="ABO93774"/>
        <property type="gene ID" value="OSTLU_28845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28845"/>
    <dbReference type="eggNOG" id="KOG2794">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035731_0_0_1"/>
    <dbReference type="OMA" id="YMDIIWR"/>
    <dbReference type="OrthoDB" id="1530at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04823">
        <property type="entry name" value="ALAD_PBGS_aspartate_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000019">
        <property type="entry name" value="Delta-aminolevulinic acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006762">
        <property type="entry name" value="PRK09283.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458:SF0">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="11">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="11">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047651"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO93774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="386" mass="42385" checksum="4E2EDCAFC59C3FB2" modified="2007-05-15" version="1">MLSTTITTPSAFVKPQAPRTRVKARADSTMAPPTTRVPPRNPEGAPTVVPQDLPSRPRRNRRSPTVRKAFRETILTPDNFIYPIFVHEGDENIPIGSMPGQDRLSFKNGMIKQVREARAAGVNQVVVFPKTPDNLKTACGKEAFNPNGLAQRSISLLKDTFPDLEVYTDVALDPYNTMGHDGMVRSDGVVMNDETVYYLCQQAVSQARAGADVISPSDMMDGRVGAIRQALDDEGFTNVAIMSYTAKYNSAYYGPFRDALASAPRPGSEDWKIPKDKAEYQMDPANYRECLREAALDEQEGADIMMVKPAGAYLDIIRALRDSTTLPISAYQVSGEYSMLKAAAAAGYLNERDAVLESLIAIKRAGADLTLTYYAIDAAKWIQEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRC1</accession>
    <name>A4RRC1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_86166</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
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    <dbReference type="STRING" id="436017.A4RRC1"/>
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    <dbReference type="Gramene" id="ABO94165">
        <property type="protein sequence ID" value="ABO94165"/>
        <property type="gene ID" value="OSTLU_86166"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86166"/>
    <dbReference type="eggNOG" id="ENOG502QQIS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_450835_0_0_1"/>
    <dbReference type="OMA" id="RNTTIYW"/>
    <dbReference type="OrthoDB" id="497162at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013946">
        <property type="entry name" value="NCA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08637">
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    </dbReference>
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    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="301"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="744" mass="83044" checksum="8FF0AB31DD8C2FF7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRC2</accession>
    <name>A4RRC2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_92148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415509.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="4999410"/>
    <dbReference type="Gramene" id="ABO93838">
        <property type="protein sequence ID" value="ABO93838"/>
        <property type="gene ID" value="OSTLU_92148"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92148"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_443059_0_0_1"/>
    <dbReference type="OMA" id="YCEESHE"/>
    <dbReference type="OrthoDB" id="497860at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="183"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="617" mass="67518" checksum="F5B7393829F2A65B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRG5</accession>
    <name>A4RRG5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_29009</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415896.1">
        <property type="nucleotide sequence ID" value="XM_001415859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRG5"/>
    <dbReference type="STRING" id="436017.A4RRG5"/>
    <dbReference type="GeneID" id="4999432"/>
    <dbReference type="Gramene" id="ABO94188">
        <property type="protein sequence ID" value="ABO94188"/>
        <property type="gene ID" value="OSTLU_29009"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29009"/>
    <dbReference type="eggNOG" id="KOG1531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050669_4_0_1"/>
    <dbReference type="OMA" id="EVYIIYT"/>
    <dbReference type="OrthoDB" id="239812at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.80:FF:000001">
        <property type="entry name" value="ATP synthase gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.80">
        <property type="entry name" value="ATP synthase, gamma subunit, helix hairpin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF22">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039089">
        <property type="entry name" value="ATP_synthase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="328" mass="35328" checksum="278D5475E1696AF8" modified="2007-05-15" version="1">MSTNAMRRNAALAVRCAMREGARGTMMTPKSTTAPRAGTMVNASEGVPANVRTVSLQAVAIRMRSVGNIQKITKAMKMVAASRLKGAQTKCEKSRALVNPFVRLLGDTPGTETDSTLVVPISSDKGLCGGINTAVVKYSTVLNAMSPGARINVVGDKARAQLNRLYPDRINNVVVDTTKQPLTFGTASAIADEIMAQNAPKTQLVFNRFASAISFKPTVATVLSSEELEKAAEEGVNEFDSYEIEGPDRSEFLLDLSEFKMGALLYNAMLENNTSELGSRMQSMENSSKNASDMLQKLTLLYNRTRQAAITTELIEIISGASSLESKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRK6</accession>
    <name>A4RRK6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_3057</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415918.1">
        <property type="nucleotide sequence ID" value="XM_001415881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRK6"/>
    <dbReference type="STRING" id="436017.A4RRK6"/>
    <dbReference type="GeneID" id="4999832"/>
    <dbReference type="Gramene" id="ABO94210">
        <property type="protein sequence ID" value="ABO94210"/>
        <property type="gene ID" value="OSTLU_3057"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3057"/>
    <dbReference type="eggNOG" id="KOG0600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="EPSHEFQ"/>
    <dbReference type="OrthoDB" id="28397at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000273">
        <property type="entry name" value="Cyclin-dependent kinase C-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000272">
        <property type="entry name" value="Cyclin-dependent kinase C-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="9"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="311"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="332" mass="38166" checksum="D9F6B48C7765991A" modified="2007-05-15" version="1" fragment="single">WGARSVECYEKLEQVGEGTYGQVYMARCKETQDIVALKKIRMDNEKEGFPITAIREIKILKKLRHKNVVDLKEIVTSKANASNGHKGSIYLVFEYMDHDLTGLAERPGMKFSLPQIKCYMKQLLTGLHYCHINNILHRDIKGSNLLINNNGVLKLADFGLAKSITNENANPLTNRVITLWYRPPELLLGATQYGPSVDMWSAGCIFAELVHGKPILPGKGEMEQLDLIFRLCGTPTPENWPDADKLPYAKHFKQKKHYPRRLREVFARFSPSAKDLVERFLTLDPAKRITAIQALDSDWFWEDPIACEPEDLPRYEPSHEFQTKKRRQEAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRN1</accession>
    <name>A4RRN1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_40339</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415597.1">
        <property type="nucleotide sequence ID" value="XM_001415560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRN1"/>
    <dbReference type="STRING" id="436017.A4RRN1"/>
    <dbReference type="GeneID" id="4999997"/>
    <dbReference type="Gramene" id="ABO93889">
        <property type="protein sequence ID" value="ABO93889"/>
        <property type="gene ID" value="OSTLU_40339"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40339"/>
    <dbReference type="eggNOG" id="KOG3157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059988_2_1_1"/>
    <dbReference type="OMA" id="PLEWHMI"/>
    <dbReference type="OrthoDB" id="10264196at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06822">
        <property type="entry name" value="PLPDE_III_YBL036c_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000014">
        <property type="entry name" value="Pyridoxal phosphate homeostasis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="5">
        <location>
            <begin position="24"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="25738" checksum="E0038F67FE58773A" modified="2007-05-15" version="1">MASQTARQLSDVVARVASAAAKANRAQGAVRLVAVSKTKPVEQLKECYDAGHRDFGENYVQEMIEKVPRMPEDTRWHFIGHLQSNKCKALLEACPRLAMLETVDSAKLANKLNAAVPEGRVDALRVLVQVNTSGEASKHGVEPGDCVTLAKHIVSECPRLKFAGLMTIGMPDYTSKPENFETLRKCREEVCAALGMSESECELSMGMSGDFEAAIAMGSTNVRVGSTIFGARDYSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRQ0</accession>
    <name>A4RRQ0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415939.1">
        <property type="nucleotide sequence ID" value="XM_001415902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRQ0"/>
    <dbReference type="GeneID" id="4999532"/>
    <dbReference type="Gramene" id="ABO94231">
        <property type="protein sequence ID" value="ABO94231"/>
        <property type="gene ID" value="OSTLU_29096"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29096"/>
    <dbReference type="HOGENOM" id="CLU_2641398_0_0_1"/>
    <dbReference type="OMA" id="MVDKFPG"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="85" mass="9225" checksum="7973C9FBE6BD11C2" modified="2007-05-15" version="1">MATATVTLERRRRVATRAVEDDEGASRDYVKPVQEENALLESETFSTVLKAGFAAFCLVCVLLVFKLAGPVVNEMVSTFPGASSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRQ1</accession>
    <name>A4RRQ1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA-polymerase II-associated protein 3-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29097</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415609.1">
        <property type="nucleotide sequence ID" value="XM_001415572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRQ1"/>
    <dbReference type="STRING" id="436017.A4RRQ1"/>
    <dbReference type="GeneID" id="4999666"/>
    <dbReference type="Gramene" id="ABO93901">
        <property type="protein sequence ID" value="ABO93901"/>
        <property type="gene ID" value="OSTLU_29097"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29097"/>
    <dbReference type="eggNOG" id="KOG4648">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_788428_0_0_1"/>
    <dbReference type="OMA" id="YYECAGR"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025986">
        <property type="entry name" value="RPAP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47329">
        <property type="entry name" value="OS05G0129900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47329:SF1">
        <property type="entry name" value="OS05G0129900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13877">
        <property type="entry name" value="RPAP3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-polymerase II-associated protein 3-like C-terminal" evidence="3">
        <location>
            <begin position="219"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="352" mass="38412" checksum="0352DAD0BFE735D7" modified="2007-05-15" version="1">MRRARVSAEGAPAVNERAREATAQRERGNAAYREGKYAAAIEHYDASCAVERNAAALANRAMCWLKLEKWDAAEADCSSALALDAVAFGVKAYQRRGMARREMGKYLESAMDFEEALRLEPTSKILKEERAKSQRAFELEAKIRPTQARVKIPVEHDRAVERGDDSLVDVDMGAVENAASCARDSVETSRRPAPAPETGRDDDLVSKAAAIAASKPVVAPRNGAEFERAYRREMKAAASTTSASRRAEILILVPPDKLETMFAGGLDPDILADVATIALEHWYAKDENASAALEWLERLRAVPRFAVSAALRPSASSRALERAFAAARATAARDARATARLEALREAFRVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRR6</accession>
    <name>A4RRR6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_40414</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. CGFS subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415947.1">
        <property type="nucleotide sequence ID" value="XM_001415910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRR6"/>
    <dbReference type="STRING" id="436017.A4RRR6"/>
    <dbReference type="GeneID" id="4999644"/>
    <dbReference type="Gramene" id="ABO94239">
        <property type="protein sequence ID" value="ABO94239"/>
        <property type="gene ID" value="OSTLU_40414"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40414"/>
    <dbReference type="eggNOG" id="KOG0911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026126_2_1_1"/>
    <dbReference type="OMA" id="TKLMPQC"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:monoatomic cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014434">
        <property type="entry name" value="Monothiol_GRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF72">
        <property type="entry name" value="MONOTHIOL GLUTAREDOXIN-S14, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005894">
        <property type="entry name" value="Monothiol_GRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 10" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="11">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11959" checksum="CA555F7157E6F54D" modified="2007-05-15" version="1">MGPELRESIDAFVAEHRVVLFMKGTKDAPRCGFSNTCVQILNSMNVPFADVDILANEDLRQGMKDYSSWPTFPQLYVGGEFFGGCDITVDAFKDGSLKEELERAMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRR9</accession>
    <name>A4RRR9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_39523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415618.1">
        <property type="nucleotide sequence ID" value="XM_001415581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRR9"/>
    <dbReference type="STRING" id="436017.A4RRR9"/>
    <dbReference type="GeneID" id="4999888"/>
    <dbReference type="Gramene" id="ABO93910">
        <property type="protein sequence ID" value="ABO93910"/>
        <property type="gene ID" value="OSTLU_39523"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39523"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016785_3_2_1"/>
    <dbReference type="OMA" id="PKLYWHY"/>
    <dbReference type="OrthoDB" id="496616at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="81"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="26396" checksum="F4665BF12055DF4E" modified="2007-05-15" version="1">MAKRGEDGESSDCGTPIVLDALVKHWPAVTKWRDGAYLDEIVGDRTVPVELGKTYVDDAWSQKLMTMREFMDAYVDGDDDESTRRASGGADVGYLAQHELFEQCPELKRDIEEPLYCALGTGTVCAVNAWFGPAHTESPAHTDPHHNLLCQVIGVKRVRLFAPSETPKMYPRDAPMSNTSRVDVMHPNLDEFPLFVDVEFIDATLYPGDALYIPPGWWHRVKAATVSFSVSYWWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRU2</accession>
    <name>A4RRU2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415629.1">
        <property type="nucleotide sequence ID" value="XM_001415592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRU2"/>
    <dbReference type="GeneID" id="5000045"/>
    <dbReference type="Gramene" id="ABO93921">
        <property type="protein sequence ID" value="ABO93921"/>
        <property type="gene ID" value="OSTLU_29137"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29137"/>
    <dbReference type="HOGENOM" id="CLU_2889877_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="63" mass="6353" checksum="AF14F99A666C47AA" modified="2007-05-15" version="1">MYFTTSSASFARAHSSCASPAVHAPAPPAHMCSSTLHECGASAYASLLRASSNASHAAANSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS27</accession>
    <name>A4RS27_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_29222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carotenoid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416007.1">
        <property type="nucleotide sequence ID" value="XM_001415970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS27"/>
    <dbReference type="STRING" id="436017.A4RS27"/>
    <dbReference type="GeneID" id="4999995"/>
    <dbReference type="Gramene" id="ABO94299">
        <property type="protein sequence ID" value="ABO94299"/>
        <property type="gene ID" value="OSTLU_29222"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29222"/>
    <dbReference type="eggNOG" id="KOG4254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019722_2_1_1"/>
    <dbReference type="OMA" id="FTMRWVF"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734:SF1">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="521" mass="57370" checksum="0EB42D1AE1458113" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT08</accession>
    <name>A4RT08_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">monogalactosyldiacylglycerol synthase</fullName>
            <ecNumber evidence="2">2.4.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MgdA</name>
        <name evidence="8" type="ORF">OSTLU_119506</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.46" evidence="2"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416396.1">
        <property type="nucleotide sequence ID" value="XM_001416359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT08"/>
    <dbReference type="STRING" id="436017.A4RT08"/>
    <dbReference type="CAZy" id="GT28">
        <property type="family name" value="Glycosyltransferase Family 28"/>
    </dbReference>
    <dbReference type="GeneID" id="5000095"/>
    <dbReference type="Gramene" id="ABO94689">
        <property type="protein sequence ID" value="ABO94689"/>
        <property type="gene ID" value="OSTLU_119506"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119506"/>
    <dbReference type="eggNOG" id="ENOG502QPXV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028367_3_2_1"/>
    <dbReference type="OMA" id="IHPYWIN"/>
    <dbReference type="OrthoDB" id="200404at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046509">
        <property type="term" value="F:1,2-diacylglycerol 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009695">
        <property type="entry name" value="Diacylglyc_glucosyltr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050519">
        <property type="entry name" value="Glycosyltransf_28_UgtP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43025">
        <property type="entry name" value="MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43025:SF3">
        <property type="entry name" value="MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06925">
        <property type="entry name" value="MGDG_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Diacylglycerol glucosyltransferase N-terminal" evidence="7">
        <location>
            <begin position="130"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="6">
        <location>
            <begin position="328"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="501" mass="55370" checksum="3606D01E06DE04D1" modified="2007-05-15" version="1">MLGADTTQSASLLAATERVNLGSKSMTMLRDASYGFECRRTVRSPKRSTGVKCSVQDLSIDVEINDMNISAVLKAQSGRPLNSGECVISNAQQMKTCSNVDVGGRSPSDFIGHRSGRRVMCLMSDTGGGHRASAQALKDCFELIYGDEFSVHIVDLWSSNSPWPFSKMPNSYFFLVKNPWLWRLNFRCSEPRLLHEIMFKGYTVIVSKHFARAFKEIDPHLIVSVHPLMQHVPMRVLQQMHKQSLISRVPFATVVTDLTRCHATWFHRSVDRCFVATNLVAAQAMRLGLKSEQIACHGLPIRPSFSARRQLSKHELRTKLALDTDAPTVMLVGGGEGMGKLQETAEALAQTLRSTHQVIVVCGRNLRLSDFLQSKVWPLKMVVKGFVHNMAEYMSACDCVISKAGPGTIAEAMICGVPIVLNGCIPCQEEGNIPFVTDNKVGAYSENPRTIAQIVAEWLAPENNAELLAMSSRARALGRPEATFDIIRDLAALVTETQECD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT78</accession>
    <name>A4RT78_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aspartyl/asparaginy/proline hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartyl/asparaginyl beta-hydroxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416121.1">
        <property type="nucleotide sequence ID" value="XM_001416084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT78"/>
    <dbReference type="GeneID" id="5000205"/>
    <dbReference type="Gramene" id="ABO94413">
        <property type="protein sequence ID" value="ABO94413"/>
        <property type="gene ID" value="OSTLU_29968"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29968"/>
    <dbReference type="eggNOG" id="ENOG502R38E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_461098_0_0_1"/>
    <dbReference type="OrthoDB" id="411451at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007803">
        <property type="entry name" value="Asp/Arg/Pro-Hydrxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05118">
        <property type="entry name" value="Asp_Arg_Hydrox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aspartyl/asparaginy/proline hydroxylase" evidence="2">
        <location>
            <begin position="468"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="592" mass="66172" checksum="BDCA6D2410218368" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTW6</accession>
    <name>A4RTW6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_30412</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416567.1">
        <property type="nucleotide sequence ID" value="XM_001416530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTW6"/>
    <dbReference type="STRING" id="436017.A4RTW6"/>
    <dbReference type="GeneID" id="5001005"/>
    <dbReference type="Gramene" id="ABO94860">
        <property type="protein sequence ID" value="ABO94860"/>
        <property type="gene ID" value="OSTLU_30412"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30412"/>
    <dbReference type="eggNOG" id="KOG0257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051433_0_0_1"/>
    <dbReference type="OMA" id="SKTFNMT"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009862">
        <property type="term" value="P:systemic acquired resistance, salicylic acid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000099">
        <property type="entry name" value="LL-diaminopimelate aminotransferase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019942">
        <property type="entry name" value="DapL/ALD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03542">
        <property type="entry name" value="DAPAT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43144">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="28"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="402" mass="43227" checksum="A8ABA9DED6150E90" modified="2007-05-15" version="1">MAQLKAGYLFPEIARIRNAHLEKNPDAKIISLGIGDTTEPIPKPITDGMVAAAAALGTKEGYSAKGGYGPEAGQMELRKTIAEKLYKGTPITYEDVFASDGSKCDISRMLQMFGSGRKIAVQDPSYPAYVDSSVIMGHSTGFNDAVKQYENITYMPCGAENDFFPDLSAAKSAELIFFCSPNNPTGAAATRAQLTELVNQALESGSIIIYDAAYSAFVGNPDCPKTIYEIPGAEKCAIETCSFSKYAGFTGLRLGWTVFPEALKFSDGSSVRQDWTRMMGTSFNGASTVAQGAGLACLTDAGLAAMGDMVAFYKENAAILKRTWEEMGYKVYGGTDAPYVWVSFEGRDSWEVFTEILDKTDIVTTPGAGFGPAGNGYVRCSAFGSRENINEAARRLKESFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU48</accession>
    <name>A4RU48_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416894.1">
        <property type="nucleotide sequence ID" value="XM_001416857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU48"/>
    <dbReference type="GeneID" id="5000763"/>
    <dbReference type="Gramene" id="ABO95187">
        <property type="protein sequence ID" value="ABO95187"/>
        <property type="gene ID" value="OSTLU_14533"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14533"/>
    <dbReference type="HOGENOM" id="CLU_1505854_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="179" mass="19670" checksum="C9DB09CEF684EA13" modified="2007-05-15" version="1">MAATTTAATGRGGRRARARDAALPRLRFIDGEEEDARAARDGADADDRDAREEKKNEVGRGEEEGEETGASGEREATGGGAGETKVAIVIVPEYEADAADATESDRKRMRSIRRRLVQTPEHREKERLRSQRRRDALTPAQKRAAADAKIARRKHQRLAKEAVEAARLLAGQRKGHATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUC6</accession>
    <name>A4RUC6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416646.1">
        <property type="nucleotide sequence ID" value="XM_001416609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUC6"/>
    <dbReference type="STRING" id="436017.A4RUC6"/>
    <dbReference type="GeneID" id="5000967"/>
    <dbReference type="Gramene" id="ABO94939">
        <property type="protein sequence ID" value="ABO94939"/>
        <property type="gene ID" value="OSTLU_30574"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30574"/>
    <dbReference type="eggNOG" id="ENOG502S7PR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1436634_0_0_1"/>
    <dbReference type="OMA" id="QVNAWRL"/>
    <dbReference type="OrthoDB" id="498085at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021518">
        <property type="entry name" value="DUF3181"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11378">
        <property type="entry name" value="DUF3181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="189" mass="20704" checksum="9540D31FD336F35C" modified="2007-05-15" version="1">MRPSLLTSDRAQHSAARLSRARDAVARQRAAFQRFQTTRGSDGFASTSSRESPACSAVRESTRTRATPKDTNVFIESFFDLADTVAGGREGPGFSKLAERIGDDVYVQVNAWRLYTRDMKFHDGLAKVFAVKIAQNSNKIDDAVIDEVLGVVRVPLGGGKSDVPLGDLCPSPSVNNLKNILRDYVDDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUS2</accession>
    <name>A4RUS2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AIG1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_30720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417009.1">
        <property type="nucleotide sequence ID" value="XM_001416972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUS2"/>
    <dbReference type="STRING" id="436017.A4RUS2"/>
    <dbReference type="GeneID" id="5000894"/>
    <dbReference type="Gramene" id="ABO95302">
        <property type="protein sequence ID" value="ABO95302"/>
        <property type="gene ID" value="OSTLU_30720"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30720"/>
    <dbReference type="eggNOG" id="ENOG502QSV2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051932_0_0_1"/>
    <dbReference type="OMA" id="ENGSRCK"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006703">
        <property type="entry name" value="G_AIG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045058">
        <property type="entry name" value="GIMA/IAN/Toc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903">
        <property type="entry name" value="GTPASE, IMAP FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903:SF149">
        <property type="entry name" value="TRANSLOCASE OF CHLOROPLAST 33, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04548">
        <property type="entry name" value="AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51720">
        <property type="entry name" value="G_AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="AIG1-type G" evidence="5">
        <location>
            <begin position="70"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="36912" checksum="9A89A109252CA555" modified="2007-05-15" version="1">MSEEEYSEDEDYVSSEGEGVEGTEEGGEGQPAQAAAPVLGPKEWVGLSSMPAATQSALLETLGKLRERNVNEMTVIFIGKQGVGKSSTVNTLLNERVAPSSPFQPENVRPLLAGRVAAGFTLNVLDTPGLLEGDSVSARGLMALRAALNGRKVDAFVFTDRLDTWRVDNADKAIFTSLAENFGAELWERTVLGFSHAQTTPTDGRPYEEFVNARVEQYRKAIRSTLNMPNLALPFALIENGSRCKTNGNGEKVVNDRPWLSDMVSTMVEMACSKDGYEYDHGKAGKKLDPNNKHKIWILPLFLFQAFVLRPLVIGQIRRDIKKADEKKQRAAAAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUT8</accession>
    <name>A4RUT8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416730.1">
        <property type="nucleotide sequence ID" value="XM_001416693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUT8"/>
    <dbReference type="GeneID" id="5001077"/>
    <dbReference type="Gramene" id="ABO95023">
        <property type="protein sequence ID" value="ABO95023"/>
        <property type="gene ID" value="OSTLU_30737"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30737"/>
    <dbReference type="HOGENOM" id="CLU_3109784_0_0_1"/>
    <dbReference type="OrthoDB" id="10549062at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="51" mass="5682" checksum="A6252CB7D68C17A4" modified="2007-05-15" version="1">MRALPKGSRYAKQQCELIEKALDILARGKRRGARSAEEEDELAGLLKAVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV01</accession>
    <name>A4RV01_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC(ATP-binding) family transporter (Fe-S assembly/SufBCD system)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_14765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416756.1">
        <property type="nucleotide sequence ID" value="XM_001416719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV01"/>
    <dbReference type="STRING" id="436017.A4RV01"/>
    <dbReference type="GeneID" id="5000573"/>
    <dbReference type="Gramene" id="ABO95049">
        <property type="protein sequence ID" value="ABO95049"/>
        <property type="gene ID" value="OSTLU_14765"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14765"/>
    <dbReference type="eggNOG" id="ENOG502QS88">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_48_1_1"/>
    <dbReference type="OMA" id="DFIMFDE"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204:SF1">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="214" mass="23593" checksum="79F33ECFFC5B468D" modified="2007-05-15" version="1">MGKNGSGKSTLTKVLVGHPAYEVTSGSATFKGEALFEMEPEERARSGLFLSFQSPIEVPGVSNTDFLRMMCNERRKARGEEELDPLEFYGYLTPKLEALNMDPSFLTRNVNEGFSGGEKKRNEILQLAVMESEMSILDEIDSGLDVDALRDVAKAVNLLRQGDKGLLLITHYQRLLDAIHPNFVHIMQKGQIVQTGGVEIATQLEEGGFASLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV21</accession>
    <name>A4RV21_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenoprotein T</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416767.1">
        <property type="nucleotide sequence ID" value="XM_001416730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV21"/>
    <dbReference type="STRING" id="436017.A4RV21"/>
    <dbReference type="GeneID" id="5000745"/>
    <dbReference type="Gramene" id="ABO95060">
        <property type="protein sequence ID" value="ABO95060"/>
        <property type="gene ID" value="OSTLU_30820"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30820"/>
    <dbReference type="eggNOG" id="ENOG502SDDD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2077042_0_0_1"/>
    <dbReference type="OrthoDB" id="60822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019389">
        <property type="entry name" value="Selenoprotein_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13544">
        <property type="entry name" value="SELENOPROTEIN T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13544:SF0">
        <property type="entry name" value="THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="12892" checksum="AF53272968A04196" modified="2007-05-15" version="1">MATTGGHWPPSATAVALGRAFSWVQIALWTATFFGERAATRVFGESAVVPAWLKSMSENKFQTAIMTFWVFNIVSANVLNTGAFEVFYDGELVSSKLQSGKLPRVDTIFEGIRAIQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV54</accession>
    <name>A4RV54_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_14802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417079.1">
        <property type="nucleotide sequence ID" value="XM_001417042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV54"/>
    <dbReference type="GeneID" id="5001122"/>
    <dbReference type="Gramene" id="ABO95372">
        <property type="protein sequence ID" value="ABO95372"/>
        <property type="gene ID" value="OSTLU_14802"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14802"/>
    <dbReference type="eggNOG" id="KOG1836">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_531454_0_0_1"/>
    <dbReference type="OMA" id="SEMANEM"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="513" mass="56406" checksum="CB9321F165B28BD7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV55</accession>
    <name>A4RV55_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1995 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_5800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416783.1">
        <property type="nucleotide sequence ID" value="XM_001416746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV55"/>
    <dbReference type="STRING" id="436017.A4RV55"/>
    <dbReference type="GeneID" id="5000737"/>
    <dbReference type="Gramene" id="ABO95076">
        <property type="protein sequence ID" value="ABO95076"/>
        <property type="gene ID" value="OSTLU_5800"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5800"/>
    <dbReference type="eggNOG" id="ENOG502R5HU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052261_0_0_1"/>
    <dbReference type="OMA" id="FWNAGEM"/>
    <dbReference type="OrthoDB" id="199922at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044687">
        <property type="entry name" value="LPA3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34051">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34051:SF1">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1995" evidence="1">
        <location>
            <begin position="3"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="277" mass="30880" checksum="B230DD7C4A8F54B5" modified="2007-05-15" version="1" fragment="single">PFPRDYAELERQARESVKRCAKDGVELVELQFPPGGLELASGDLEGNVECNLTTERLRGICDAFVANGTASTTRVLFPDPTEMRLATTGANAAPDGIRAPEQSDTRGWFADWKGTLDYVDDPSFMSVSGFDKIFGGKKNISERMRGDETAYVVAYPSANISELANTRDLYEGCVRGTGKSLVVCNGELERTRSNYYPPFWNAGEMGPLRSFCRKFEGAYVIYNFKGSNPAVLFRVYPEPWQVFRRRKGGRDGLETLERVCTFEKFESVKSVALDVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV88</accession>
    <name>A4RV88_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">carotenoid 9,10-dioxygenase</fullName>
            <ecNumber evidence="5">1.14.99.n4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_86865</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>all-trans-zeaxanthin + 2 O2 = 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial + 2 (3R)-hydroxy-beta-ionone</text>
            <dbReference type="Rhea" id="RHEA:26393"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:27547"/>
            <dbReference type="ChEBI" id="CHEBI:53171"/>
            <dbReference type="ChEBI" id="CHEBI:53173"/>
            <dbReference type="EC" id="1.14.99.n4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.n4" evidence="5"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416800.1">
        <property type="nucleotide sequence ID" value="XM_001416763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV88"/>
    <dbReference type="GeneID" id="5001109"/>
    <dbReference type="Gramene" id="ABO95093">
        <property type="protein sequence ID" value="ABO95093"/>
        <property type="gene ID" value="OSTLU_86865"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86865"/>
    <dbReference type="eggNOG" id="KOG1285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016472_6_3_1"/>
    <dbReference type="OMA" id="CIDHPHV"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF89">
        <property type="entry name" value="CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="547"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="554" mass="60971" checksum="6CEADF4981038DDA" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVI1</accession>
    <name>A4RVI1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417424.1">
        <property type="nucleotide sequence ID" value="XM_001417387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVI1"/>
    <dbReference type="STRING" id="436017.A4RVI1"/>
    <dbReference type="GeneID" id="5001145"/>
    <dbReference type="Gramene" id="ABO95717">
        <property type="protein sequence ID" value="ABO95717"/>
        <property type="gene ID" value="OSTLU_30983"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30983"/>
    <dbReference type="HOGENOM" id="CLU_308676_0_0_1"/>
    <dbReference type="OMA" id="LGAFWDD"/>
    <dbReference type="OrthoDB" id="10623056at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="956" mass="102490" checksum="5783F04A253E3842" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVU2</accession>
    <name>A4RVU2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Impact N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_37283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417468.1">
        <property type="nucleotide sequence ID" value="XM_001417431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVU2"/>
    <dbReference type="GeneID" id="5001595"/>
    <dbReference type="Gramene" id="ABO95761">
        <property type="protein sequence ID" value="ABO95761"/>
        <property type="gene ID" value="OSTLU_37283"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37283"/>
    <dbReference type="eggNOG" id="KOG3299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083552_3_1_1"/>
    <dbReference type="OMA" id="YWIENER"/>
    <dbReference type="OrthoDB" id="498744at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF20">
        <property type="entry name" value="IMPACT FAMILY MEMBER YIGZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="2">
        <location>
            <begin position="55"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="UPF0029" evidence="3">
        <location>
            <begin position="179"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="25710" checksum="C629183D67E1CA0D" modified="2007-05-15" version="1">MLSSTLRAIGENLNLVPSRSSIFRRSLASRRAPAPPRASSYRTPSDVCRVETEVKKSRFVALAAPCASADDALRFVKERSDLSASHNCWAFRYGEAQYRFSDDGEPGGTAGQPILNAVTASGLDHCVVLVTRYYGGTQLGTGGLIRAYGGAAQSALELAAKEATEVRAKVDAVVNAAPGDLGKIFLALDEFAAEKIDEEYSDDGSVHIQIECEEEVAETLKERLANATSGRASFKFWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW53</accession>
    <name>A4RW53_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dof-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_9704</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417524.1">
        <property type="nucleotide sequence ID" value="XM_001417487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW53"/>
    <dbReference type="STRING" id="436017.A4RW53"/>
    <dbReference type="GeneID" id="5001254"/>
    <dbReference type="Gramene" id="ABO95817">
        <property type="protein sequence ID" value="ABO95817"/>
        <property type="gene ID" value="OSTLU_9704"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9704"/>
    <dbReference type="eggNOG" id="ENOG502QSI8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_206246_0_0_1"/>
    <dbReference type="OMA" id="PRFYCKK"/>
    <dbReference type="OrthoDB" id="1927254at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045174">
        <property type="entry name" value="Dof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003851">
        <property type="entry name" value="Znf_Dof"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31089">
        <property type="entry name" value="CYCLIC DOF FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31089:SF1">
        <property type="entry name" value="CYCLIC DOF FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02701">
        <property type="entry name" value="Zn_ribbon_Dof"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01361">
        <property type="entry name" value="ZF_DOF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50884">
        <property type="entry name" value="ZF_DOF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Dof-type" evidence="7">
        <location>
            <begin position="15"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="66" mass="7872" checksum="CAB56242BF93110A" modified="2007-05-15" version="1" fragment="single">DEKKREPLPKPDYAVACPRCKSDDTKFCYYNNYNIKQPRFYCKKCCRYWTEGGSLRNVRVGAGRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWD6</accession>
    <name>A4RWD6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_31302</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Membrane</location>
            <topology evidence="2 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PRA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417310.1">
        <property type="nucleotide sequence ID" value="XM_001417273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWD6"/>
    <dbReference type="STRING" id="436017.A4RWD6"/>
    <dbReference type="GeneID" id="5001491"/>
    <dbReference type="Gramene" id="ABO95603">
        <property type="protein sequence ID" value="ABO95603"/>
        <property type="gene ID" value="OSTLU_31302"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31302"/>
    <dbReference type="HOGENOM" id="CLU_1268735_0_0_1"/>
    <dbReference type="OMA" id="AHAYHES"/>
    <dbReference type="OrthoDB" id="10474928at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23020" checksum="38375DF0F799EA90" modified="2007-05-15" version="1">MSSAGAGAGAGAGADDVLDARETLADGGKRLARALRGPFARAQPHWKSFAQLTFACPTASEVPGRMKKNLQQFGYCYVSLAAALAAYNALSRALLAVMLAGAFIGHHYVTRVRRAPIEIGGRVFGAKTQGVACAAATAIFFWKFITDVFFSAASVALAFAAAHAVMRVPEPKTDEDEGEIPLLRDFAAAYRESGADDYVPPQVSSTVRGLFASVFARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWD8</accession>
    <name>A4RWD8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_87073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417312.1">
        <property type="nucleotide sequence ID" value="XM_001417275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWD8"/>
    <dbReference type="STRING" id="436017.A4RWD8"/>
    <dbReference type="GeneID" id="5001618"/>
    <dbReference type="Gramene" id="ABO95605">
        <property type="protein sequence ID" value="ABO95605"/>
        <property type="gene ID" value="OSTLU_87073"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87073"/>
    <dbReference type="eggNOG" id="KOG2265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113495_0_0_1"/>
    <dbReference type="OMA" id="RDVECSL"/>
    <dbReference type="OrthoDB" id="515366at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF18">
        <property type="entry name" value="NUDC DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="1">
        <location>
            <begin position="16"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="17436" checksum="41DAD25D78B94884" modified="2007-05-15" version="1">MDRLAPPARRAHVLACGRVAYEWEQTLDAVSVYVRAPPGARGRDLDVALEPTRARVGVKGNAPYMEHELWARVKASESTWTLADGELALTLVKATRGEAWRSPFAAHGDASDAKEDERDKQRLMLERFQAENPGFDFSDASFNGQTVPDASTFMGGCGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWU5</accession>
    <name>A4RWU5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417636.1">
        <property type="nucleotide sequence ID" value="XM_001417599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWU5"/>
    <dbReference type="GeneID" id="5001460"/>
    <dbReference type="Gramene" id="ABO95929">
        <property type="protein sequence ID" value="ABO95929"/>
        <property type="gene ID" value="OSTLU_92679"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92679"/>
    <dbReference type="eggNOG" id="ENOG502QUSY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1280629_0_0_1"/>
    <dbReference type="OMA" id="ADPYWAT"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="23932" checksum="C3A8055362AFE557" modified="2007-05-15" version="1" fragment="single">VFELVTDQIIISDTLSVRLVRPVSEDEVVEHYVANEAFDADPYWATLWPSAFAVSRYIANAPALVRDKTVCDLGAGLGLAGLVACAAGAKRVELFDREPLALACAILSIEANGFQDRVLVKDFDWNDVREDQAKFDTLLACDVLYESHAVLPVAELVPKLVKRGGGRFLLGDPPSRAPQNRKRFKETLTEQYGAFVMRELLVQEGGDELVFIDFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWV4</accession>
    <name>A4RWV4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF4203 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417889.1">
        <property type="nucleotide sequence ID" value="XM_001417852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWV4"/>
    <dbReference type="GeneID" id="5002055"/>
    <dbReference type="Gramene" id="ABO96182">
        <property type="protein sequence ID" value="ABO96182"/>
        <property type="gene ID" value="OSTLU_24487"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24487"/>
    <dbReference type="HOGENOM" id="CLU_998680_0_0_1"/>
    <dbReference type="OMA" id="WEDHAFT"/>
    <dbReference type="OrthoDB" id="10559017at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="34892" checksum="06E8CA536F1BC122" modified="2007-05-15" version="1">MPSRSLPRHRAERAAAIGQDAPGGGDAANANADAAPDAFANADAGVNTQAHASDAAASWATNVTRAALVKEYFESRAIETTIGVAALPVGIALALAGRKHDQKLTLALVAGFGVWLGLMAIDLLRDLVPNVLGDSVTIPDNDYVNYGSAAVVALILVSVAANVYKLFGVVVGLMCAVGISSVTNHIVDDVPISATIVINVVGAIGGLYLVTPFTTDKLGILFSFVGGALVAVGASFAIFVAGGVTECADTASAACNWAVPLAAGGSAKVVAKYVPDIWVLAVGTKVNAAASAGAHSFDFSNYSNYIAIGVALLFVYMGICTQGRARKGETSETSPLLGDAEKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWV9</accession>
    <name>A4RWV9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417644.1">
        <property type="nucleotide sequence ID" value="XM_001417607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWV9"/>
    <dbReference type="STRING" id="436017.A4RWV9"/>
    <dbReference type="GeneID" id="5002154"/>
    <dbReference type="Gramene" id="ABO95937">
        <property type="protein sequence ID" value="ABO95937"/>
        <property type="gene ID" value="OSTLU_31475"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31475"/>
    <dbReference type="eggNOG" id="KOG0167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1091506_0_0_1"/>
    <dbReference type="OrthoDB" id="2016400at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16655">
        <property type="entry name" value="RING-Ubox_WDSUB1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="2">
        <location>
            <begin position="31"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="255" mass="28052" checksum="EB623D78B3FCA99D" modified="2007-05-15" version="1">MANAGIGLSQFAFVGTFIAAVKKTIAGPREEPPEHLKCVITQELFRDPVVLVQTGYTYDRIAIQRWLAAKFPPTDPTSNVELWCTDLVPNWSLRQSVDEWGVANGYGAMDPPEEAVRVTKDGRPMGRRSANATSATALTHQYLQALHRTHPRHAAVLVFLMTFTLGTITVTTLTVVHSAYAAVGAALRHEAVARMLDGPAQSFVWWFCVGGFLFLAHCGAQDVPPVARGRERVDRRGRAQDVVGRGFFRRLGVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX03</accession>
    <name>A4RX03_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MsrB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417912.1">
        <property type="nucleotide sequence ID" value="XM_001417875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX03"/>
    <dbReference type="GeneID" id="5001669"/>
    <dbReference type="Gramene" id="ABO96205">
        <property type="protein sequence ID" value="ABO96205"/>
        <property type="gene ID" value="OSTLU_31519"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31519"/>
    <dbReference type="eggNOG" id="ENOG502RYJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091173_1_0_1"/>
    <dbReference type="OMA" id="AGYWEST"/>
    <dbReference type="OrthoDB" id="44061at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23315" checksum="64528D69BA627BAD" modified="2007-05-15" version="1">MRTARASLIARPLRAKASIMGASASRSSPATRAFLDGAKIPGVSDGCKGAPIPEGLKGLPIVADESVMSQKAHGTSEHAVMKNLRYGSDRELADRICNFNRHYAEHAGYAWSTNWISEVKDKGEVTYYDSVTGAPLFIAPRGRTWAEFEKESRAHGWPSFRDAEMVQENVRCLRDGECVSTTGTHLGHNLPDRNGNRYCINLVSVAGNPEPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX45</accession>
    <name>A4RX45_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_6297</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sterol desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417694.1">
        <property type="nucleotide sequence ID" value="XM_001417657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX45"/>
    <dbReference type="STRING" id="436017.A4RX45"/>
    <dbReference type="GeneID" id="5002042"/>
    <dbReference type="Gramene" id="ABO95987">
        <property type="protein sequence ID" value="ABO95987"/>
        <property type="gene ID" value="OSTLU_6297"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6297"/>
    <dbReference type="eggNOG" id="KOG0872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047036_2_1_1"/>
    <dbReference type="OMA" id="PTHFATH"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="7">
        <location>
            <begin position="53"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="22011" checksum="5868004D5964BA25" modified="2007-05-15" version="1" fragment="single">KDQVKNEIVLSVWSIAVMTFMIAPFELMVEAGWTKLYWDVDKYGMTYFCLTPLLFLVFSDTCIYWIHRGLHHRAVYAPIHKLHHKYKDTTPFSAYAFHPLDGWLQGCPYHLFIFLFPMHHMTYFISLAIVGLWTINIHDRVSMRFPYVNCAAHHTIHHTGFNYNYGQYFTFWDKIGGSYRDPHSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX52</accession>
    <name>A4RX52_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417696.1">
        <property type="nucleotide sequence ID" value="XM_001417659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX52"/>
    <dbReference type="GeneID" id="5002047"/>
    <dbReference type="Gramene" id="ABO95989">
        <property type="protein sequence ID" value="ABO95989"/>
        <property type="gene ID" value="OSTLU_31571"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31571"/>
    <dbReference type="HOGENOM" id="CLU_2363512_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="96" mass="10522" checksum="22E4645AC83092F8" modified="2007-05-15" version="1">MCVVSLDYFAAVLAGPLAGLKLRLSASLFPPRNRMREKSSSRTSHVRTAPRSATRQPMLCDGTSKGESRRLSVAMVRSLTGEWPYTVLCLPQPVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX80</accession>
    <name>A4RX80_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_31598</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417706.1">
        <property type="nucleotide sequence ID" value="XM_001417669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX80"/>
    <dbReference type="STRING" id="436017.A4RX80"/>
    <dbReference type="GeneID" id="5001910"/>
    <dbReference type="Gramene" id="ABO95999">
        <property type="protein sequence ID" value="ABO95999"/>
        <property type="gene ID" value="OSTLU_31598"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31598"/>
    <dbReference type="eggNOG" id="KOG4652">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_680412_0_0_1"/>
    <dbReference type="OMA" id="INWMEKG"/>
    <dbReference type="OrthoDB" id="1928087at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051294">
        <property type="entry name" value="HORMA_MeioticProgression"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225">
        <property type="entry name" value="HORMA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225:SF7">
        <property type="entry name" value="MEIOSIS-SPECIFIC PROTEIN HOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="7">
        <location>
            <begin position="14"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="405" mass="44288" checksum="98B5757EA51B76AD" modified="2007-05-15" version="1">MTTTIDASKQLTREKSAAMVTNMLRVALHTVTFCRGIFDAETHFKECKNMNVSMHKLVPASKGAKRILDMLERGVADALERGYLRSVSFALTRAVVKDGVKDATMRETVEEYKFNVRYGSRGEVTLDDARYIGGGDRGDVSVGLSDRTGKTTRMERLSDVDYIKKAAIAMTRCLLSLVKTLENVPDGCAFNIHVSYVNGTPADYEPPFFEAADATRETTWSKNPFSMSVGKVETEYHGLSLRVRSVLDPAQDTDSGQKSNPGSSQTSSLLDESPSTPVGDKTAADDAIVPMSQDVVVNLSQPKAEAAPTFDDGEVEAQVLDWVKTRRSSGIVDAVACSNTFRAYPFKVIDRAFERLLAKGLVEKNGDRGFVLSSAPKTNGKKRSASTKAIAPQATRRCLRSNTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX96</accession>
    <name>A4RX96_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417714.1">
        <property type="nucleotide sequence ID" value="XM_001417677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX96"/>
    <dbReference type="STRING" id="436017.A4RX96"/>
    <dbReference type="GeneID" id="5001698"/>
    <dbReference type="Gramene" id="ABO96007">
        <property type="protein sequence ID" value="ABO96007"/>
        <property type="gene ID" value="OSTLU_31615"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31615"/>
    <dbReference type="eggNOG" id="KOG2972">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062974_0_0_1"/>
    <dbReference type="OMA" id="HTWIASP"/>
    <dbReference type="OrthoDB" id="2017544at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048300">
        <property type="entry name" value="TACO1_YebC-like_2nd/3rd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049083">
        <property type="entry name" value="TACO1_YebC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009044">
        <property type="entry name" value="PRK12378.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01033">
        <property type="entry name" value="YebC/PmpR family DNA-binding transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532:SF0">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20772">
        <property type="entry name" value="TACO1_YebC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="YebC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TACO1/YebC-like N-terminal" evidence="3">
        <location>
            <begin position="21"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="TACO1/YebC-like second and third" evidence="2">
        <location>
            <begin position="98"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="254" mass="26966" checksum="B864A25E6570AD1A" modified="2007-05-15" version="1">MPSNAPARARTYRASDVTCGRKAAKIAQKKGKTDAARTKLYGRYGKLIAQTVKQGGSADPVANAALGKLLKQAQAANVPRDLIERNIKKAAEGKSGDYFELTYEVYGAGGVGIVCEVLTDNVNRAASETRTAATKAGGKMAESGSVMFNFNRRGVCVLDGGDEEAVFEAAMEAGAEDIVPRRDGAEGWDVVCELDDFSAVQDALSEAGFTINEDTGLKCIPINEIETSDEDADVNDKIIDALLDLDDVDAVYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXU3</accession>
    <name>A4RXU3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.205</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2'-O-ribose RNA methyltransferase TRM7 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_12560</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42396"/>
            <dbReference type="Rhea" id="RHEA-COMP:10246"/>
            <dbReference type="Rhea" id="RHEA-COMP:10247"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.205"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.205" evidence="9"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418056.1">
        <property type="nucleotide sequence ID" value="XM_001418019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXU3"/>
    <dbReference type="STRING" id="436017.A4RXU3"/>
    <dbReference type="GeneID" id="5001765"/>
    <dbReference type="Gramene" id="ABO96349">
        <property type="protein sequence ID" value="ABO96349"/>
        <property type="gene ID" value="OSTLU_12560"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12560"/>
    <dbReference type="eggNOG" id="KOG1099">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009422_1_2_1"/>
    <dbReference type="OMA" id="FIVCLNF"/>
    <dbReference type="OrthoDB" id="289250at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106340">
        <property type="term" value="F:tRNA (guanosine(34)-2'-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000040">
        <property type="entry name" value="Putative ribosomal RNA methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03162">
        <property type="entry name" value="RNA_methyltr_E_TRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028590">
        <property type="entry name" value="RNA_methyltr_E_TRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF12">
        <property type="entry name" value="TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="10">
        <location>
            <begin position="21"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="32712" checksum="B1A60ADDF88FE448" modified="2007-05-15" version="1">MGKSSKDKRDIYYRKAKEEGWRARSAFKLLQIDESFDIFRDVRHVVDLCAAPGSWSQVLSRKLYLPALARGVEEEELPKIVAIDLQPMAPIEGVTTIQGDITSMDKVREVLSHFDGKHADLIVGDGAPDVTGLHDLDEFMQAQLILAGLTVATHILKPGGTFIAKIFRGKDISLLYSQLKIFFPEVTCAKPKSSRNSSIEAFIVCQGYSPPEGFEPHQLTRILEARATSHAAGDEGAAVGTKSWPNNVLVPFLACGDLSGYDADQSYALDDTKVRLKPVQPPTTPAYMNAIKLLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXW4</accession>
    <name>A4RXW4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_94380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417823.1">
        <property type="nucleotide sequence ID" value="XM_001417786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXW4"/>
    <dbReference type="STRING" id="436017.A4RXW4"/>
    <dbReference type="GeneID" id="5001717"/>
    <dbReference type="Gramene" id="ABO96116">
        <property type="protein sequence ID" value="ABO96116"/>
        <property type="gene ID" value="OSTLU_94380"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94380"/>
    <dbReference type="eggNOG" id="KOG2374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1247156_0_0_1"/>
    <dbReference type="OrthoDB" id="514381at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018610">
        <property type="entry name" value="UVSSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049408">
        <property type="entry name" value="UVSSA_N_a-solenoid_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28670">
        <property type="entry name" value="UV-STIMULATED SCAFFOLD PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28670:SF1">
        <property type="entry name" value="UV-STIMULATED SCAFFOLD PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20867">
        <property type="entry name" value="UVSSA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="222" mass="25419" checksum="24E79B5D2101A184" modified="2007-05-15" version="1">MQSSRASAATRARAVTTTSELFERSRLFRELTLDRLEVLMKYTIGTDDDIPLPDVPKGEGDRLRQHAIDVLEAWEAKFKTQYKQLTLARKFVTERLGDDAPEARAERAQRLTAEKEREVQSKLQNRWLAIKTELPALLDEIDDARNAACECFRLLFGDRFVTEFNDESSFASKDRSASTSTTVNDTIQSMREDECEDDWEDVVDGAVKDWRFAQAMRGAEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY12</accession>
    <name>A4RY12_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31888</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418091.1">
        <property type="nucleotide sequence ID" value="XM_001418054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY12"/>
    <dbReference type="GeneID" id="5002003"/>
    <dbReference type="Gramene" id="ABO96384">
        <property type="protein sequence ID" value="ABO96384"/>
        <property type="gene ID" value="OSTLU_31888"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31888"/>
    <dbReference type="HOGENOM" id="CLU_1931055_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="14120" checksum="6BC8ADB08F83BCEB" modified="2007-05-15" version="1">MDAATEEEATVVFVVETAEGDEPAAEARDAVKMILREAKARNGDGAGDARGRRYATAMVGDCDIIGDRAAYRSNQSVVEDCNAVGLAVDAALRRFGWTRAAESLRVDKSKEDDDAWRRGRSAAVDAWVAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY91</accession>
    <name>A4RY91_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Malate dehydrogenase</fullName>
            <ecNumber evidence="2 10">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_87414</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 10">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="2 10"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418129.1">
        <property type="nucleotide sequence ID" value="XM_001418092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY91"/>
    <dbReference type="STRING" id="436017.A4RY91"/>
    <dbReference type="GeneID" id="5002288"/>
    <dbReference type="Gramene" id="ABO96422">
        <property type="protein sequence ID" value="ABO96422"/>
        <property type="gene ID" value="OSTLU_87414"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87414"/>
    <dbReference type="eggNOG" id="KOG1496">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040727_2_0_1"/>
    <dbReference type="OMA" id="HTWVNGT"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000010">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000002">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003916">
        <property type="entry name" value="PRK05442.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="3 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="11">
        <location>
            <begin position="11"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="12">
        <location>
            <begin position="161"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="16"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="134"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO96422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="335" mass="35631" checksum="B9CA2CD1F8FC45C3" modified="2007-05-15" version="1">MPASTVDDVVTVLITGAAGQIGYALAPMVCAGAATGPGKKIALKLLDVEFASEALRGVKMEIMDCAFDACVSVDVFTDCEKACEGVDVAIMVGGFPRKQGMERKDVLGKNVAIYKQQASALASKAKKDVKIVVVANPANTNAKILAKFAPSIPRGNVTCMTRLDHNRALAQLGERSGKATIEVKNAIIWGNHSSTQYPDVNHATIEGKPAREVIGNDAYLDGDFVDVVRARGAAIIEARKLSSALSAASSVCDHVYDWIHGTKEGEWTSMGVISDGSYGVPEGLVYSFPVTCTGGKWQIVQGLSIDERSRKLMDESAKELTEEFELAEQCLAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYE8</accession>
    <name>A4RYE8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_32003</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATG12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418371.1">
        <property type="nucleotide sequence ID" value="XM_001418334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYE8"/>
    <dbReference type="STRING" id="436017.A4RYE8"/>
    <dbReference type="GeneID" id="5002257"/>
    <dbReference type="Gramene" id="ABO96664">
        <property type="protein sequence ID" value="ABO96664"/>
        <property type="gene ID" value="OSTLU_32003"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32003"/>
    <dbReference type="eggNOG" id="KOG3439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106795_3_1_1"/>
    <dbReference type="OMA" id="CMIDILL"/>
    <dbReference type="OrthoDB" id="10003551at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="1 4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="97" mass="10756" checksum="39DDD29C20F83B7F" modified="2007-05-15" version="1">MPPDLDPSRRVVVLFKATGDAPILRQNKVRVRADARFEDVVAHLSKLIKRERAFAYLGAAFTPSYDARVGALCDGYGERNDEGGRLVVFYSTTPAWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYM8</accession>
    <name>A4RYM8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ribosome maturation protein SBDS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_5118</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDO1/SBDS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418418.1">
        <property type="nucleotide sequence ID" value="XM_001418381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYM8"/>
    <dbReference type="STRING" id="436017.A4RYM8"/>
    <dbReference type="GeneID" id="5002581"/>
    <dbReference type="Gramene" id="ABO96711">
        <property type="protein sequence ID" value="ABO96711"/>
        <property type="gene ID" value="OSTLU_5118"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5118"/>
    <dbReference type="eggNOG" id="KOG2917">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043216_1_1_1"/>
    <dbReference type="OMA" id="TIISAKC"/>
    <dbReference type="OrthoDB" id="10253092at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1250.10">
        <property type="entry name" value="Ribosome maturation protein SBDS, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.900">
        <property type="entry name" value="SBDS protein C-terminal domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036786">
        <property type="entry name" value="Ribosome_mat_SBDS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002140">
        <property type="entry name" value="Sdo1/SBDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039100">
        <property type="entry name" value="Sdo1/SBDS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018978">
        <property type="entry name" value="SDO1/SBDS_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037188">
        <property type="entry name" value="Sdo1/SBDS_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019783">
        <property type="entry name" value="SDO1/SBDS_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00291">
        <property type="entry name" value="RNA_SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927:SF1">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09377">
        <property type="entry name" value="SBDS_domain_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01172">
        <property type="entry name" value="SBDS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89895">
        <property type="entry name" value="FYSH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109728">
        <property type="entry name" value="Hypothetical protein AF0491, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS N-terminal" evidence="8">
        <location>
            <begin position="12"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS central" evidence="9">
        <location>
            <begin position="107"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="26347" checksum="1A3A4B32F12155F3" modified="2007-05-15" version="1" fragment="single">MFQPVGIKKLTNVAVVRHKTHGSRFEIACYKNTVLSYRRGHEKDLDNVLQSSEVYVNVSKGVVARDEELVRAYGTTDRGKICEIILAKGELQVSERERKAESESAFRDAVTTLVEKCVNPGTNRPYPPGMIESALRDIHFSVDPKRSAKQQALEALPKLQEIFPIKRAEMRFAAVVPSAKEESLMAFVRENSGKVETNDLSASEASVTFTMDPSTYRALDKLVKECKGRLEVVTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYT4</accession>
    <name>A4RYT4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3456 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_8305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418449.1">
        <property type="nucleotide sequence ID" value="XM_001418412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYT4"/>
    <dbReference type="STRING" id="436017.A4RYT4"/>
    <dbReference type="GeneID" id="5002326"/>
    <dbReference type="Gramene" id="ABO96742">
        <property type="protein sequence ID" value="ABO96742"/>
        <property type="gene ID" value="OSTLU_8305"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8305"/>
    <dbReference type="eggNOG" id="ENOG502RXZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102372_0_0_1"/>
    <dbReference type="OMA" id="HLKCLVC"/>
    <dbReference type="OrthoDB" id="192915at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021852">
        <property type="entry name" value="DUF3456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11938">
        <property type="entry name" value="DUF3456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672983" description="DUF3456 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3456" evidence="2">
        <location>
            <begin position="22"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="180" mass="20202" checksum="6FC100F4E585EF8F" modified="2007-05-15" version="1" fragment="single">LALALALVVARASSTAEAIEAKCSACRAVGKSLAKALREDAESADGKVVDMRGRLDSRGRRYGKRISYKVSELRFVELLDGVCDEPSRVGKYQLHEETNRWRIPPNPVKKIRHARGKQMKTEILGYCHRVIEESEEALQAAVLEERLDAESNVEEFLCRNVSKACDESVDFSEEEPKDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYU8</accession>
    <name>A4RYU8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_94506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418456.1">
        <property type="nucleotide sequence ID" value="XM_001418419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYU8"/>
    <dbReference type="STRING" id="436017.A4RYU8"/>
    <dbReference type="GeneID" id="5002379"/>
    <dbReference type="Gramene" id="ABO96749">
        <property type="protein sequence ID" value="ABO96749"/>
        <property type="gene ID" value="OSTLU_94506"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94506"/>
    <dbReference type="eggNOG" id="ENOG502QRQ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1197517_0_0_1"/>
    <dbReference type="OrthoDB" id="691424at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006502">
        <property type="entry name" value="PDDEXK-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579">
        <property type="entry name" value="OS03G0796600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579:SF1">
        <property type="entry name" value="OS03G0796600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04720">
        <property type="entry name" value="PDDEXK_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="232" mass="26170" checksum="7DAD04252F781DF0" modified="2007-05-15" version="1" fragment="single">MNQPAPSMGDMEFDMLFEEDAMDFERDRTPRRDDGATTVGFDVSAVVVRTARLLCTPRGEEAYRTLKALKWAVREIGLDAFKDDSRVSHVRESGLEELMMKLRENDPVKFGRLERATSETPREGDVSDALKKLNHSFLWLPPSVLIGDSDAHALAYASADERIIIEPNLRSHFVVGRATAQYARLVESMPTAFVGTYAQLSEIVFFMSTHMINSFRESGLDIPPWRRPSALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ24</accession>
    <name>A4RZ24_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphoribosylglycinamide formyltransferase 1</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_6266</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418500.1">
        <property type="nucleotide sequence ID" value="XM_001418463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ24"/>
    <dbReference type="STRING" id="436017.A4RZ24"/>
    <dbReference type="GeneID" id="5002585"/>
    <dbReference type="Gramene" id="ABO96793">
        <property type="protein sequence ID" value="ABO96793"/>
        <property type="gene ID" value="OSTLU_6266"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6266"/>
    <dbReference type="eggNOG" id="KOG3076">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038395_1_3_1"/>
    <dbReference type="OMA" id="CGGADYA"/>
    <dbReference type="OrthoDB" id="2018833at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369:SF2">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="5">
        <location>
            <begin position="3"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="206" mass="22088" checksum="50A3C9C0C7890908" modified="2007-05-15" version="1" fragment="single">RANLAVFVSGGGSNMRAIHDACERGEVRGRVACVVTNAATCGGAEWARERGIPVLIYPAKKNETGGLTADALVDALTREHGAEFVLLAGYLRLIPPELCRAYENRMVNIHPALLPAFGGKGMHGENVHKAVVASGARFTGPTIHFVNEAFDEGKILAQTVVPVFDDDDASAVAARVLAQEHILFPRVVAAMCEDRIRFRSDGVPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ70</accession>
    <name>A4RZ70_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein translocase subunit SecA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_49779</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + chloroplast-proteinSide 1 = ADP + phosphate + chloroplast-proteinSide 2.</text>
            <dbReference type="EC" id="7.4.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418525.1">
        <property type="nucleotide sequence ID" value="XM_001418488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ70"/>
    <dbReference type="STRING" id="436017.A4RZ70"/>
    <dbReference type="GeneID" id="5002487"/>
    <dbReference type="Gramene" id="ABO96818">
        <property type="protein sequence ID" value="ABO96818"/>
        <property type="gene ID" value="OSTLU_49779"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49779"/>
    <dbReference type="eggNOG" id="ENOG502QS62">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005314_3_0_1"/>
    <dbReference type="OMA" id="IGQIHEF"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016464">
        <property type="term" value="F:chloroplast protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17928">
        <property type="entry name" value="DEXDc_SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1440.10:FF:000003">
        <property type="entry name" value="Preprotein translocase SecA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3060.10">
        <property type="entry name" value="Helical scaffold and wing domains of SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1440.10">
        <property type="entry name" value="SecA, preprotein cross-linking domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009538">
        <property type="entry name" value="PRK12904.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612:SF11">
        <property type="entry name" value="PROTEIN TRANSLOCASE SUBUNIT SECA2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21090">
        <property type="entry name" value="P-loop_SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="Helical scaffold and wing domains of SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="Pre-protein crosslinking domain of SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SecA family profile" evidence="13">
        <location>
            <begin position="3"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="89"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="918" mass="103175" checksum="5A4D1BD11CAB728E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ73</accession>
    <name>A4RZ73_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="5 15">1.3.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_32279</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="15">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Plastid</location>
            <location evidence="2 15">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="5 15"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418278.1">
        <property type="nucleotide sequence ID" value="XM_001418241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ73"/>
    <dbReference type="STRING" id="436017.A4RZ73"/>
    <dbReference type="GeneID" id="5002525"/>
    <dbReference type="Gramene" id="ABO96571">
        <property type="protein sequence ID" value="ABO96571"/>
        <property type="gene ID" value="OSTLU_32279"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32279"/>
    <dbReference type="eggNOG" id="KOG1276">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009629_3_0_1"/>
    <dbReference type="OMA" id="WFDQWFG"/>
    <dbReference type="OrthoDB" id="419752at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009534">
        <property type="term" value="C:chloroplast thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3110.10:FF:000002">
        <property type="entry name" value="Protoporphyrinogen oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3110.10">
        <property type="entry name" value="protoporphyrinogen ix oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.20">
        <property type="entry name" value="Protoporphyrinogen oxidase, mitochondrial, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9 15" id="KW-0274">FAD</keyword>
    <keyword evidence="7 15" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12 15" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="13 15" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Amine oxidase" evidence="16">
        <location>
            <begin position="8"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO96571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="472" mass="50477" checksum="F7DA6CAB12B48B41" modified="2007-05-15" version="1">MKKMREATVLVTEARERVGGNVTSRSDGTYTWEEGPNSYQPGDAILTLACDAGMRDDILLADPASNRYVLWDGKLRILPHSIESAVLGDFLTWPGKIRAGLGAIGIRPPAPGKEESVKEFVSRNLGTEAFERLIEPFCSGVYAGDPAALSSVAATGRVQRLEPLGGSLVAGAIMAQKEAAQNKKPRDPRLPEVKGQTVGSFRGGLKTFPEGLAKQLGDDVVKCNWKLVGVSKSAEGGYECAYDTPEGPQTVRTKCLLLTAPAYVAAEMVKDMAPAAATALNKFYYPPVASVTISYKKDSFRLDGTSALPEGGLTGFGQLHPRSQGIRTLGTIYSSSLFKDDKRQPDDEFMILNYIGGARDVAIKDLSEEELVKQVHEDALKTILKPGTPLPKVVGVKVWEKAIPQFNLGHLDVLAEAENALTAADCGEKDGLFLGGNYTAGVALGRCVEFGIEQADEVVAYLNAASKKAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZB1</accession>
    <name>A4RZB1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="3">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Formylglycinamide ribonucleotide amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Formylglycinamide ribotide amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_41441</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418300.1">
        <property type="nucleotide sequence ID" value="XM_001418263.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RZB1"/>
    <dbReference type="GeneID" id="5002510"/>
    <dbReference type="Gramene" id="ABO96593">
        <property type="protein sequence ID" value="ABO96593"/>
        <property type="gene ID" value="OSTLU_41441"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41441"/>
    <dbReference type="eggNOG" id="KOG1907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001031_0_0_1"/>
    <dbReference type="OMA" id="LSANWMW"/>
    <dbReference type="OrthoDB" id="6666987at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01740">
        <property type="entry name" value="GATase1_FGAR_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02203">
        <property type="entry name" value="PurL_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02204">
        <property type="entry name" value="PurL_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000024">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000007">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.750:FF:000001">
        <property type="entry name" value="Putative phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.750">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055181">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003672">
        <property type="entry name" value="PRK05297.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22689">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13507">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01211">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109736">
        <property type="entry name" value="FGAM synthase PurL, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="PurS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase N-terminal" evidence="16">
        <location>
            <begin position="67"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase linker" evidence="15">
        <location>
            <begin position="210"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="14">
        <location>
            <begin position="474"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT PurM N-terminal-like" evidence="17">
        <location>
            <begin position="693"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="14">
        <location>
            <begin position="879"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO96593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1348" mass="144515" checksum="2C1D27D3DB867C1C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZI3</accession>
    <name>A4RZI3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_12673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418576.1">
        <property type="nucleotide sequence ID" value="XM_001418539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZI3"/>
    <dbReference type="STRING" id="436017.A4RZI3"/>
    <dbReference type="GeneID" id="5002197"/>
    <dbReference type="Gramene" id="ABO96869">
        <property type="protein sequence ID" value="ABO96869"/>
        <property type="gene ID" value="OSTLU_12673"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12673"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OMA" id="NSNFPAW"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19094">
        <property type="entry name" value="AKR_Tas-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF17">
        <property type="entry name" value="ALDO KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="355" mass="38935" checksum="4446195D35D7368A" modified="2007-05-15" version="1">MTWGVQNTEAEAHEQLDYAIKQRGVNFIDTAEMYPVPMSDPSWMPGTTEKFIGSWLAKNSSAVREDVVLATKIAGFGASAKIVGNRRREETTATGRLDRASIKSACDASLARLQTDYIDLYQIHWPDRYVPIGAFFGSPAYNPALERADAVPIRESVEALGELIKAGKIKHYGLSNESTFGVCEFVRAADELGVPRPVSIQNSFCLLHRGFETELAEACAPSNFDIGLLPWTPLGGGALTGKYLDGASNAAEGRLVKYAKYGFHQRYLNDPSRVATAEYKKIADEAGVTLATLALAWCKSRFYVSSTIIGATSMTQLKENIDAFGPDIVLSEETLVEIDRVHERCRDPSIMSDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZI7</accession>
    <name>A4RZI7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418578.1">
        <property type="nucleotide sequence ID" value="XM_001418541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZI7"/>
    <dbReference type="GeneID" id="5002286"/>
    <dbReference type="Gramene" id="ABO96871">
        <property type="protein sequence ID" value="ABO96871"/>
        <property type="gene ID" value="OSTLU_32402"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32402"/>
    <dbReference type="HOGENOM" id="CLU_1247157_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="222" mass="24437" checksum="8E8375B265A9FE33" modified="2007-05-15" version="1">MSSARDDGDDVFMTSLSTLDAPTRPAATSDERASEEPNGQATSADDESASTANCSHAICIENLERAMTSYARASESCSRAEDELRQRTMTRRREDVKGLLRDEAERVERLCDANTRFFLPSSKTSMGVDAHVVFRGVTSPRVEDLSFGAAVDGAVERARVAYRRKRSLLKATAISLEDVDASLEETNRVLDVLGEVDTDGDEDENAASLRHVDRALRECRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZM3</accession>
    <name>A4RZM3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_87673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418822.1">
        <property type="nucleotide sequence ID" value="XM_001418785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZM3"/>
    <dbReference type="STRING" id="436017.A4RZM3"/>
    <dbReference type="GeneID" id="5002918"/>
    <dbReference type="Gramene" id="ABO97115">
        <property type="protein sequence ID" value="ABO97115"/>
        <property type="gene ID" value="OSTLU_87673"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87673"/>
    <dbReference type="eggNOG" id="ENOG502SRQM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_690002_0_0_1"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009664">
        <property type="term" value="P:plant-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22271">
        <property type="entry name" value="DPBB_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002963">
        <property type="entry name" value="Expansin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31867">
        <property type="entry name" value="EXPANSIN-A15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Expansin-like EG45" evidence="1">
        <location>
            <begin position="38"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="400" mass="44451" checksum="CA6D36DC7DD673B5" modified="2007-05-15" version="1" fragment="single">VRVDAAVGSWSRARATYFDAPDAWKKTFAKQIFGDLYGNACGFVNKGEGLESNENLPYARDAVAAVADYDLKLHEGACGSCFEVRCVSGFVLKDFSGGRIEYSRERGFWEVDPDALDSYGRKVPARPAKRDDATSTEYEFVRCWDESLVIKVKIIDTCPCDYEYGTQEICCGPVPHFDLSFYAFEKLAHPIQGKMNIEFRPVSCGEDSRRLDVDLGARARVEAKIYDGGLGAGWALLPYRDRWLVINREGYGRMESSSALCGEFSPRGRVAFHCWLCEISAKPFANVSSVSVWIRISCTDNFDVSLIIGLSHRTRKQWRNGTVLTPAVETQVGRKFRLDPGSSSSDYEIDAQCGRSFVVPIDAFRASSSDLARVNTLAIEVPSDVSDPVSFCVDALRARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0E4</accession>
    <name>A4S0E4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_5177</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418958.1">
        <property type="nucleotide sequence ID" value="XM_001418921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0E4"/>
    <dbReference type="STRING" id="436017.A4S0E4"/>
    <dbReference type="GeneID" id="5002938"/>
    <dbReference type="Gramene" id="ABO97251">
        <property type="protein sequence ID" value="ABO97251"/>
        <property type="gene ID" value="OSTLU_5177"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5177"/>
    <dbReference type="eggNOG" id="KOG2249">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049519_0_0_1"/>
    <dbReference type="OMA" id="DNGFSYH"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06144">
        <property type="entry name" value="REX4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037431">
        <property type="entry name" value="REX4_DEDDh_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF123">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="4"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="31263" checksum="C254217A87028443" modified="2007-05-15" version="1" fragment="single">TQKKPCACCHKFFADSTALEAHWKLVQHSAHDAVCNACGRHFPSYDTLRQHLVGNLPKASCAEAYKRAGCERCYEIFQDDEATASHACIFRETEDADDDVDDWPCVALDCEFVGVGEAGEKHACARVCVVGSSGEILLHTWVNPGEEVTDYREELTGATPEKLADAPSLERVRAIVVQILLGKAVQTRREHVGVKHLLIGHSVEHDLEVLDIKWKKGMRRDTAQFPLYLRHTHLPFKLRALAEQFLGEKIQEEGEAHDPCVDARISMRLYQAAKRRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0M8</accession>
    <name>A4S0M8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_46171</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419004.1">
        <property type="nucleotide sequence ID" value="XM_001418967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0M8"/>
    <dbReference type="STRING" id="436017.A4S0M8"/>
    <dbReference type="GeneID" id="5002792"/>
    <dbReference type="Gramene" id="ABO97297">
        <property type="protein sequence ID" value="ABO97297"/>
        <property type="gene ID" value="OSTLU_46171"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_46171"/>
    <dbReference type="eggNOG" id="KOG2767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026663_1_1_1"/>
    <dbReference type="OMA" id="MINIGAS"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.350:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="8">
        <location>
            <begin position="271"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="152"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="436" mass="48466" checksum="963464D50D7315AB" modified="2007-05-15" version="1">MAMINIGASNAGDQFYRYKMPAIQSKIEGRGNGIKTNVTNLVEVSKALARPPMYTLKFLGNDLGAQTTFNEKEGRAIVNGAHDAGKLAQSLESFIKRFVQCFSCGNPETMIEITKRETIHLKCKACGALSDVDMRHKLCGYICKNPPEIKKDKKEKQLRRAEREREEAGAAIDDEERRRRKSEKKEKKEKKEKKEKKEKKEKKEKKEKTDDAPAEAGDASSASEADDDDDDEVQWATDTSAAAAKARAIEQLTDGAANMVTVVADKMADAAIEDESSEEEEDPRVSKLRAYAAKNDAVKTAEYLVSDALGVESKEMGVLFLLEAVFDEDEAIPPQIKAKKDYLSAACPDAALQRALLCAFERYVTETATSGFKAFSLILNQLYEFDLIEEDVIKAWNEDVDAASCIDVEPKVAQAVRKQAAKFIDWLDESEDEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0W7</accession>
    <name>A4S0W7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HTR3503</name>
        <name evidence="11" type="ORF">OSTLU_32891</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419259.1">
        <property type="nucleotide sequence ID" value="XM_001419222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0W7"/>
    <dbReference type="STRING" id="436017.A4S0W7"/>
    <dbReference type="GeneID" id="5003459"/>
    <dbReference type="Gramene" id="ABO97552">
        <property type="protein sequence ID" value="ABO97552"/>
        <property type="gene ID" value="OSTLU_32891"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32891"/>
    <dbReference type="eggNOG" id="KOG1745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078295_4_0_1"/>
    <dbReference type="OMA" id="HIFAEMA"/>
    <dbReference type="OrthoDB" id="494251at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000078">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000044">
        <property type="entry name" value="Histone H3.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="136" mass="15386" checksum="FEE9422EB2E9EBFF" modified="2007-05-15" version="1">MARTKQTARKSTGGKAPRKQLATKAARKSAPTTGGVKKPHRYRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSTAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S124</accession>
    <name>A4S124_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419288.1">
        <property type="nucleotide sequence ID" value="XM_001419251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S124"/>
    <dbReference type="STRING" id="436017.A4S124"/>
    <dbReference type="GeneID" id="5003361"/>
    <dbReference type="Gramene" id="ABO97581">
        <property type="protein sequence ID" value="ABO97581"/>
        <property type="gene ID" value="OSTLU_24899"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24899"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059661_0_0_1"/>
    <dbReference type="OMA" id="IERGDCH"/>
    <dbReference type="OrthoDB" id="2013833at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="26"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="390" mass="43400" checksum="C05FC6435C67C5F1" modified="2007-05-15" version="1">MPHPDATLIPCANAPLGFDPDDLTHRDAWRQVGDGSFGKVYRGELLGEPVAIKVTANARPDRIAGLKRDLWYLNAFAHPNITRVYGAFIERGDCHMVMEFVPHSLRSKRVVNETNRVKALADVARALTRVHAAGHVHRDVKARNVLISEDYQTAKLTDFGLARVLPGGTTSAREDVNPRLTPKIGPPKYRAPEVESGAPYDCSSDIYGYGVMCFQLVEQLRRRTRKTNADEVEFIRELGRLATQTNPAKRPTARQCLVMCMSWLRGGDDVITPDIYPGRDTFREKYWVHDPMDGGTWKHDAEPSKSPSDSDSEDEPLSPSERIVVDGDEFAHNNRSVDAQRGTKRDEREGSDTPVSAPPINSAKRVNSTSTDLHVRGELEAVRLNANGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1F1</accession>
    <name>A4S1F1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_46449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419138.1">
        <property type="nucleotide sequence ID" value="XM_001419101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1F1"/>
    <dbReference type="GeneID" id="5003460"/>
    <dbReference type="Gramene" id="ABO97431">
        <property type="protein sequence ID" value="ABO97431"/>
        <property type="gene ID" value="OSTLU_46449"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_46449"/>
    <dbReference type="HOGENOM" id="CLU_1700061_0_0_1"/>
    <dbReference type="OrthoDB" id="513765at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="9"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="155" mass="18146" checksum="61D740B09335560F" modified="2007-05-15" version="1" fragment="single">MLLKRKGRKVWEKWFEELITFQQRTGLTNPPYEEGVTTGLGAWLEEQRELYRIGELVDKREERLRAQGIAFDSLEALEELALELRAFLNENGEYAEPNVNSPLGVWVIKTRAKVRDGTIRDEDMQALEQLNLDMVYIPESWVAMLNVYADMRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1I2</accession>
    <name>A4S1I2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419152.1">
        <property type="nucleotide sequence ID" value="XM_001419115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1I2"/>
    <dbReference type="GeneID" id="5003477"/>
    <dbReference type="Gramene" id="ABO97445">
        <property type="protein sequence ID" value="ABO97445"/>
        <property type="gene ID" value="OSTLU_93143"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93143"/>
    <dbReference type="HOGENOM" id="CLU_856171_0_0_1"/>
    <dbReference type="OMA" id="NRQAQIF"/>
    <dbReference type="OrthoDB" id="10501774at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="36438" checksum="7F6B7B274E7C7333" modified="2007-05-15" version="1">MGGIRGKSARKRAKMAQNSKTFDRISGRFYDEKVAMPSGKVSEDVMLSAPKSFKRFLAAKAAAESRSKRRDRVEDDDSEEEEPAAAKERGEEKVDDVGEESSEDDRGEATNRNISGEGALTSVAPLVRAQPDKGNATLRAMDEKAATAAREAEAEAKKKKKKHLSLRERKKRDRVALRAQKEEEAEFLRGGGNTVRFGEVAEAPPTITLKRKSGGKGEKEVPIAQSGHKIVEIAENQTGGKSNRQSKIFADLLSAAKGSSAKSKKKSETQGLKRTADLAALRAQVISDYRSMKGRPMNNGRNVKLASNPTKLFQSGAGSLQGVGGISAAQLRKDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1N7</accession>
    <name>A4S1N7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amino-acid N-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_1828</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. ArgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419181.1">
        <property type="nucleotide sequence ID" value="XM_001419144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1N7"/>
    <dbReference type="STRING" id="436017.A4S1N7"/>
    <dbReference type="GeneID" id="5003152"/>
    <dbReference type="Gramene" id="ABO97474">
        <property type="protein sequence ID" value="ABO97474"/>
        <property type="gene ID" value="OSTLU_1828"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1828"/>
    <dbReference type="eggNOG" id="KOG2436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024773_1_0_1"/>
    <dbReference type="OMA" id="KRKYNWD"/>
    <dbReference type="OrthoDB" id="438291at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01105">
        <property type="entry name" value="N_acetyl_glu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010167">
        <property type="entry name" value="NH2A_AcTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30602">
        <property type="entry name" value="AMINO-ACID ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30602:SF12">
        <property type="entry name" value="AMINO-ACID ACETYLTRANSFERASE NAGS1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000423">
        <property type="entry name" value="ArgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="7">
        <location>
            <begin position="384"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="506" mass="55315" checksum="3B56AF13228943C6" modified="2007-05-15" version="1" fragment="single">FVEFFRQASPYIALHRGSTFVVLIPGDVSASTAKMNSVVRDVSLLHDLGVRIVLVVGASDQVSELTKMRGGEVNFVDDYRVTDEAAMEAAMEANGKNQVLVQALLSRAPTISITRRHRDGDEDGAGERGMASNGANVVATSGNYIFAKRMGTVNGTDFQRTGEVTRVDAKGIKKKLSQGDIVLLSSLGFNAAGEVLNCQSFDVALATAIDLKADKLIVMTDPSHMPYEGNDSAERVPRYLPLRSAEAYLAKIYGTKDLNGGGGVNGANGVANWRWLQMEYSIDGSGTNKGDEQIVSAYSNDEREHLFDSIRGVNERISRFEELMERGLSWRVPHCPQELCLAAFACKAGVRRTHLVDPTVSGSLLVELYTRDGIGCMVARDRYEGTRIATMADWESIKRILEPLVANGAVIARSDEQLIDEVCKNYFHVTERDGKVIACCALKPCGNAPDAHEVAAFAVSPEYRRGGRGDALLEYAENYACETLATSRLFLLTTRTADWFVQRGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Y5</accession>
    <name>A4S1Y5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein TIC 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_42552</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in protein precursor import into chloroplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Tic20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419447.1">
        <property type="nucleotide sequence ID" value="XM_001419410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Y5"/>
    <dbReference type="STRING" id="436017.A4S1Y5"/>
    <dbReference type="GeneID" id="5003145"/>
    <dbReference type="Gramene" id="ABO97740">
        <property type="protein sequence ID" value="ABO97740"/>
        <property type="gene ID" value="OSTLU_42552"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42552"/>
    <dbReference type="eggNOG" id="ENOG502QUSD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094758_0_0_1"/>
    <dbReference type="OMA" id="KLMVWGH"/>
    <dbReference type="OrthoDB" id="414558at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005691">
        <property type="entry name" value="Tic20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510:SF5">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16166">
        <property type="entry name" value="TIC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="212" mass="22711" checksum="902860F38FB69793" modified="2007-05-15" version="1">MGETRTTGRRTARAGTTTTTTTTTRAVAARERSATRARGTTTVVARGYAGGGFNIVPVPDRVVALVPYLLPLLSALRYGRFFFGQFPAAVVLLKPLMPILRGVAMLPMGNLIMFFAIYLGIAKNQNLSRFCRFNGMQAILLDIALIFPSLLEALFGPGILGIGLPGIVTMIMHNAIFVVTLAAFAFAAVGCMSGQYIRFPILAEAAEAQMGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2E4</accession>
    <name>A4S2E4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PsaB translation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TAB2</name>
        <name evidence="4" type="ORF">OSTLU_88180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419517.1">
        <property type="nucleotide sequence ID" value="XM_001419480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2E4"/>
    <dbReference type="STRING" id="436017.A4S2E4"/>
    <dbReference type="GeneID" id="5003669"/>
    <dbReference type="KEGG" id="olu:OSTLU_88180"/>
    <dbReference type="eggNOG" id="ENOG502QVJR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058545_1_0_1"/>
    <dbReference type="OMA" id="FFRRQMN"/>
    <dbReference type="OrthoDB" id="3833at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009472">
        <property type="entry name" value="Tab2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046761">
        <property type="entry name" value="Tab2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046760">
        <property type="entry name" value="Tab2-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34556">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34556:SF2">
        <property type="entry name" value="PROTEIN TAB2 HOMOLOG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20429">
        <property type="entry name" value="Tab2-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06485">
        <property type="entry name" value="Tab2-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-binding protein Tab2-like N-terminal" evidence="2">
        <location>
            <begin position="101"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding protein Tab2/Atab2 C-terminal" evidence="3">
        <location>
            <begin position="220"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="42634" checksum="16EA444922987ADE" modified="2007-05-15" version="1" fragment="single">LAIHTSYPTARHRATSIRVFAFPRPSARAHRTMEAMSCVTRARIACVAPTASKPRASCAAARRSMTTPIAQPRSSTKRTAVTSNATNEATESEIKKLTTDWQIDFCSRPLRDDRGKKVWELLVTDDARTFEHAEYFPNNRINSVELARALERVMAEKKEKPRRFKFFRAQMQTIISRACNEVDVQPLASRRCQTMTKWLNERVENVYKKHPGYDASAPPLMAFEATAPKRLPDALRGESWAFVALPLVGVREEMEQVKRGRVFGATLEIDENLPDDTLIPGIAVYTSRAAALAGWTKGLELACISSDTQTSSIVLETGVNDSWSYAFFRKSPELTKEAKEWEEVKRACNGLHFLAIQTDEEAEATDGFWILQDSDPAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S331</accession>
    <name>A4S331_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA/rRNA methyltransferase SpoU type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_93288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419642.1">
        <property type="nucleotide sequence ID" value="XM_001419605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S331"/>
    <dbReference type="GeneID" id="5003512"/>
    <dbReference type="Gramene" id="ABO97935">
        <property type="protein sequence ID" value="ABO97935"/>
        <property type="gene ID" value="OSTLU_93288"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93288"/>
    <dbReference type="eggNOG" id="ENOG502S962">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049969_0_0_1"/>
    <dbReference type="OrthoDB" id="241340at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18093">
        <property type="entry name" value="SpoU-like_TrmJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786:SF2">
        <property type="entry name" value="TRNA (CYTIDINE_URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="TRNA/RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="344" mass="36455" checksum="C8431AFECC3B14D4" modified="2007-05-15" version="1" fragment="single">VSFVLCAPEGPLNVGAAARVIQNFSLPSSLRVVRPSASVLRDDDDGASAPRLHEDAYKFAVHAKWMLDDCCARGESVLEAVAEASLVVATTARPRENLPLLTLGAACEKMRDEIARGGKCAILFGNERTGLTNEELELAEFGVSIPTSATVGTSAMARRNKYSGGAGVDGSQTATSLNLGMAVGVVAYELFSQVHAVREDDETKSIGGFNQPHRLTVGERAALIDDVVAARRAVDVFADVDAEEDVIFAEKERRAITAVLSSGPIATRDATPIFMLARRARALARLADPNALVADAARAYARANGGAVPSTKSLNAYIRETLGISLTKRELERAAALVRDDLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S364</accession>
    <name>A4S364_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA polymerase</fullName>
            <ecNumber evidence="9">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_34689</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="9"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419864.1">
        <property type="nucleotide sequence ID" value="XM_001419827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S364"/>
    <dbReference type="STRING" id="436017.A4S364"/>
    <dbReference type="GeneID" id="5003869"/>
    <dbReference type="Gramene" id="ABO98157">
        <property type="protein sequence ID" value="ABO98157"/>
        <property type="gene ID" value="OSTLU_34689"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34689"/>
    <dbReference type="eggNOG" id="KOG2534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008698_1_1_1"/>
    <dbReference type="OMA" id="NYPYKKP"/>
    <dbReference type="OrthoDB" id="205514at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.210.10:FF:000002">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Heijde M."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
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                <person name="Paulsen I."/>
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                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
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            <strain evidence="3 4">CCE9901</strain>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3K7</accession>
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    </protein>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Salamov A."/>
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                <person name="Jorgensen R."/>
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                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
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                <person name="Schmutz J."/>
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            <dbReference type="PubMed" id="17460045"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="90"/>
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            <end position="276"/>
        </location>
    </feature>
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        </location>
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        <location>
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            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="616" mass="67790" checksum="7B9545BD9CB96FFE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3P4</accession>
    <name>A4S3P4_OSTLU</name>
    <protein>
        <submittedName>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420130.1">
        <property type="nucleotide sequence ID" value="XM_001420093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3P4"/>
    <dbReference type="GeneID" id="5003994"/>
    <dbReference type="Gramene" id="ABO98423">
        <property type="protein sequence ID" value="ABO98423"/>
        <property type="gene ID" value="OSTLU_38298"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38298"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_10_2_1"/>
    <dbReference type="OMA" id="PQNSIRF"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="51"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="151"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="243"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="335" mass="35576" checksum="25E538043101633F" modified="2007-05-15" version="1">MDGDAAARARRWAATKSAATGATRREDARRATAREAPFAASAIAERALAVLDGSRSVAAGGGAGIIARTASAPLDRIKLLFQVQAMASSGTSATAYTSVGQAFRKIYAEEGILSFWKGNGVNVIRVAPYAAAQLASNDYYKSLLADEQGKLGVPQRLLAGALAGMTGTAITHPLDTVRLRLALPNHGYNGMMHCFGTVYRTEGVGALYKGLGPTLAGIAPYAAINFASYDMAKKMYYGENGKEDRVSNLVVGGASGTFSATVCYPLDTIRRRMQMKGKTYNGMYDAITTIARTEGVKGFFRGWAANTLKVVPQNSIRFVSFEILKDLFGAPAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3R8</accession>
    <name>A4S3R8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420142.1">
        <property type="nucleotide sequence ID" value="XM_001420105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3R8"/>
    <dbReference type="STRING" id="436017.A4S3R8"/>
    <dbReference type="GeneID" id="5004151"/>
    <dbReference type="Gramene" id="ABO98435">
        <property type="protein sequence ID" value="ABO98435"/>
        <property type="gene ID" value="OSTLU_26150"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26150"/>
    <dbReference type="eggNOG" id="KOG2865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_4_1"/>
    <dbReference type="OMA" id="PEDQFTN"/>
    <dbReference type="OrthoDB" id="275457at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="366" mass="40717" checksum="AACEFA5206D3485C" modified="2007-05-15" version="1">MSIKPGKDFKVPPPSVTSDAVGTGGRSSFSGITCTVFGSTGFLGRYVVHHVAKSGSRMILPTRCSENDRQHLKVMGDLGQIVQLDYGIRDEETIRYAVERSNVVINMVGREWETRNFSFEDVNVTFPKKLAEICADVGVRRLVHVSALGAEEDHPSAYYRSKAAGEAAVREAFPSATIVRPAKIVGVEDRFLNIFGEHSRKYPAVPIIDGGDTKHQPVFVDDVAVAIRQIVHDELTSGRTYELAGNKVYTFDELAKMVLKTIRTRKSTAYIPSFIMKALSCPHEWLLRRVPFPMPTPLGLTRSYIDAQSRDYVKRADSLGFSDLGIEPNNIENGYVLDYLRSFRAGGYQVGDAPWEHEERDAKLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3V2</accession>
    <name>A4S3V2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419985.1">
        <property type="nucleotide sequence ID" value="XM_001419948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3V2"/>
    <dbReference type="GeneID" id="5004167"/>
    <dbReference type="Gramene" id="ABO98278">
        <property type="protein sequence ID" value="ABO98278"/>
        <property type="gene ID" value="OSTLU_26182"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26182"/>
    <dbReference type="HOGENOM" id="CLU_2007772_0_0_1"/>
    <dbReference type="OMA" id="YANTFNA"/>
    <dbReference type="OrthoDB" id="496559at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="124" mass="14298" checksum="31FCB372C882A9D9" modified="2007-05-15" version="1">MPVAVNTPRARAVVAPEFVEETMEVIDMTRALLRGEKTDEAFIDEFQTKRRAWFAKYQYHHGKSFYGYANAWNAQAKVGVQIAVNRENGVPYDSEHTAYNKDYLLSILDKAEAELFDMQKRNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4S0</accession>
    <name>A4S4S0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SUI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_44011</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DENR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420483.1">
        <property type="nucleotide sequence ID" value="XM_001420446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4S0"/>
    <dbReference type="STRING" id="436017.A4S4S0"/>
    <dbReference type="GeneID" id="5004561"/>
    <dbReference type="Gramene" id="ABO98776">
        <property type="protein sequence ID" value="ABO98776"/>
        <property type="gene ID" value="OSTLU_44011"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44011"/>
    <dbReference type="eggNOG" id="KOG3239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073511_0_1_1"/>
    <dbReference type="OMA" id="EVFEIDM"/>
    <dbReference type="OrthoDB" id="277199at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11607">
        <property type="entry name" value="DENR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050318">
        <property type="entry name" value="DENR/SUI1_TIF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046447">
        <property type="entry name" value="DENR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789:SF0">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="3">
        <location>
            <begin position="87"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="173" mass="18834" checksum="635108FAE58D92A3" modified="2007-05-15" version="1" fragment="single">PKPRRDAMEVEYCASCACPLEYCDVVGCARVAARALERVALDDDATATTTTTAAAAATRDDDDGENDDDATRKTTSKKKSKSKAREVVVTRLSRNRKKMITNVVGLERFDVDLKEASKAFGKKFACGCSVTKGATGRDELDLQGDYSEQLAALICEKYEVGAEDVRCVDKSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Z4</accession>
    <name>A4S4Z4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L38, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL38</name>
        <name evidence="5" type="ORF">OSTLU_17408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420354.1">
        <property type="nucleotide sequence ID" value="XM_001420317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Z4"/>
    <dbReference type="STRING" id="436017.A4S4Z4"/>
    <dbReference type="GeneID" id="5004533"/>
    <dbReference type="Gramene" id="ABO98647">
        <property type="protein sequence ID" value="ABO98647"/>
        <property type="gene ID" value="OSTLU_17408"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17408"/>
    <dbReference type="eggNOG" id="KOG3499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152057_2_0_1"/>
    <dbReference type="OMA" id="RCHRFIY"/>
    <dbReference type="OrthoDB" id="10258478at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022618">
        <property type="term" value="P:protein-RNA complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.90:FF:000001">
        <property type="entry name" value="60S ribosomal protein L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="8353" checksum="6E1CFA102C085A10" modified="2007-05-15" version="1">MRKQPKEISEIKDFLHTARRKDARSVKIKKTAGVTKFKVRCSKYLYTLCVKDSDKASKLKQSLPPGLQVMEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S547</accession>
    <name>A4S547_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoribosylanthranilate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_6627</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TrpF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.24" evidence="3"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420546.1">
        <property type="nucleotide sequence ID" value="XM_001420509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S547"/>
    <dbReference type="STRING" id="436017.A4S547"/>
    <dbReference type="GeneID" id="5004442"/>
    <dbReference type="Gramene" id="ABO98839">
        <property type="protein sequence ID" value="ABO98839"/>
        <property type="gene ID" value="OSTLU_6627"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6627"/>
    <dbReference type="eggNOG" id="KOG4202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076364_0_1_1"/>
    <dbReference type="OMA" id="FHGDESP"/>
    <dbReference type="OrthoDB" id="524799at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000075">
        <property type="entry name" value="Tryptophan biosynthesis protein TRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044643">
        <property type="entry name" value="TrpF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894">
        <property type="entry name" value="N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894:SF1">
        <property type="entry name" value="N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)" evidence="8">
        <location>
            <begin position="4"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="213" mass="22171" checksum="BEE60EA88895FD26" modified="2007-05-15" version="1" fragment="single">KPIVKVCGITTVRDCESACEHGANFVGMILWPKSKRSVDEATAKEIVACAKAKGAVPVAVFVDEDASEITRVCDAIGCDHAQLHGDGARDALETLPMRLKAIWVLNADANGQIVSKFPGDEENGPRRVVDWLLIDGVNAGSGTAFDWSKLKAPRGASRKGWLLAGGLNPENVAQAIETANPTGVDVASGVADEGGVVKDAAKIAAFIGNARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S554</accession>
    <name>A4S554_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L28, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL28</name>
        <name evidence="5" type="ORF">OSTLU_26642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420551.1">
        <property type="nucleotide sequence ID" value="XM_001420514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S554"/>
    <dbReference type="STRING" id="436017.A4S554"/>
    <dbReference type="GeneID" id="5004498"/>
    <dbReference type="Gramene" id="ABO98844">
        <property type="protein sequence ID" value="ABO98844"/>
        <property type="gene ID" value="OSTLU_26642"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26642"/>
    <dbReference type="eggNOG" id="KOG3412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2041963_0_0_1"/>
    <dbReference type="OMA" id="HNAFTRA"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="4">
        <location>
            <begin position="12"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="12634" checksum="1B1C4B0107587F59" modified="2007-05-15" version="1">MISHVPASDDFLWQVTKKHNAFTRASTSGHGARFSAEPGNVTAEVSFRASGLANAKTIDIREHDGGKGKPAATCDGKKLCGSFKSQAGEVKIAAKARPDLEKAALARISAINKAGRVKCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="107" xmlns="https://uniprot.org/uniprot">
    <accession>A4S591</accession>
    <name>A4S591_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="9">ATase</shortName>
            <ecNumber evidence="3 9">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_19754</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 9"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420733.1">
        <property type="nucleotide sequence ID" value="XM_001420696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S591"/>
    <dbReference type="STRING" id="436017.A4S591"/>
    <dbReference type="MEROPS" id="C44.001"/>
    <dbReference type="GeneID" id="5004796"/>
    <dbReference type="Gramene" id="ABO99026">
        <property type="protein sequence ID" value="ABO99026"/>
        <property type="gene ID" value="OSTLU_19754"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19754"/>
    <dbReference type="eggNOG" id="KOG0572">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022389_2_1_1"/>
    <dbReference type="OMA" id="IRHFGVK"/>
    <dbReference type="OrthoDB" id="191723at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="12">
        <location>
            <begin position="67"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="563" mass="61062" checksum="55B6A902636005E9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5C3</accession>
    <name>A4S5C3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26712</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420748.1">
        <property type="nucleotide sequence ID" value="XM_001420711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5C3"/>
    <dbReference type="STRING" id="436017.A4S5C3"/>
    <dbReference type="GeneID" id="5004848"/>
    <dbReference type="Gramene" id="ABO99041">
        <property type="protein sequence ID" value="ABO99041"/>
        <property type="gene ID" value="OSTLU_26712"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26712"/>
    <dbReference type="eggNOG" id="KOG4419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_7_2_1"/>
    <dbReference type="OMA" id="CTLNGDF"/>
    <dbReference type="OrthoDB" id="10252235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="633"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="669" mass="72934" checksum="C18D278F935A4D93" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-02-05" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5P6</accession>
    <name>A4S5P6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_17599</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420807.1">
        <property type="nucleotide sequence ID" value="XM_001420770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5P6"/>
    <dbReference type="STRING" id="436017.A4S5P6"/>
    <dbReference type="GeneID" id="5004906"/>
    <dbReference type="KEGG" id="olu:OSTLU_17599"/>
    <dbReference type="eggNOG" id="KOG2608">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_732793_0_0_1"/>
    <dbReference type="OMA" id="SHICEFY"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO99100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="42176" checksum="8DDA6E70E5BF10E8" modified="2007-05-15" version="1" fragment="single">MCSLDLEHKDGSEPTLRSPVTDSVDRTISTPEAEALTSIDVPETECSDEDLPTFWTDMCHKFAPEEQTEYVNLQLNPERWTGYNGSHVWRAIYEENCLKSASSVDEMCYEERVLYRLLSGMHSSINIHIALHSKPPKRALGETEWGSDPKKFVEIFAKHPERLKNLHFSFVVLLRALRKAAPALSKMDVRIGQDAEEDERTHALMSRLLESHILSSCRDVFGAFDEKSLFRDVQSTLSANSGMISGVGEELLAPVSLKSQFKDIFLNISEVMDCISCQKCKLHGKLQLLGLGSALKVLLLPEDLLESSLNKQEVVALVNTIAKFSHAIRKVPELMNAARQDALKSSVDLESVGLHLRETEGGQKVEQSPLEAAIAATAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5X2</accession>
    <name>A4S5X2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_88830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420684.1">
        <property type="nucleotide sequence ID" value="XM_001420647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5X2"/>
    <dbReference type="STRING" id="436017.A4S5X2"/>
    <dbReference type="GeneID" id="5004885"/>
    <dbReference type="Gramene" id="ABO98977">
        <property type="protein sequence ID" value="ABO98977"/>
        <property type="gene ID" value="OSTLU_88830"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88830"/>
    <dbReference type="eggNOG" id="KOG2625">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027041_0_0_1"/>
    <dbReference type="OMA" id="CIENTTR"/>
    <dbReference type="OrthoDB" id="566048at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010378">
        <property type="entry name" value="TRAPPC13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055429">
        <property type="entry name" value="TRAPPC13_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055427">
        <property type="entry name" value="TRAPPC13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23647">
        <property type="entry name" value="TRAPPC13_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06159">
        <property type="entry name" value="TRAPPC13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 13 N-terminal" evidence="2">
        <location>
            <begin position="50"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Trafficking protein particle complex subunit 13 middle" evidence="3">
        <location>
            <begin position="180"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="478" mass="50668" checksum="9F377E69B278A544" modified="2007-05-15" version="1">MRLRAPAYEHAGAREGRAIDDGDDGDDARATRGARASGADADADAGRNDDDDARRRRERETTSGELTLPQSFGAVALGERFSSFVTFGNFSEPTSGASGTAREIGIKVELQTETRRTTLRDGTKTPIETLRPGEKVDLIVTKDLKELGAHTLVCSATYYDAAGERKYSPQYFKFNVANPLSVRTKVRAAPRGRAFLEVCIENTTRYALLLDSARFDTVDGILAKDMTPEFGGAAATLHGVDDSPDAGLPSLGKRAVYRLDPSTGAAHYLFEITRANASEEPLTPQTQLGKLELRWRGAMGDPGRLQTQVITAGSAGSTAPSPVAAKMRQSIIVHPRPPDAEDVSTVYAETPFILRAAVEALAPIKADACVVRVKDVVSGVYIDGPRAVRVGALSPGQTVNVDIPCVALGLGVQTCPSLVLCDAVDDAARAAPAPLEVFSVIPPPSVVLDALKRVETIDVASPPVDVAPSLDAPIDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S620</accession>
    <name>A4S620_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_95034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420711.1">
        <property type="nucleotide sequence ID" value="XM_001420674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S620"/>
    <dbReference type="STRING" id="436017.A4S620"/>
    <dbReference type="GeneID" id="5004730"/>
    <dbReference type="Gramene" id="ABO99004">
        <property type="protein sequence ID" value="ABO99004"/>
        <property type="gene ID" value="OSTLU_95034"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_95034"/>
    <dbReference type="eggNOG" id="KOG0229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_540138_0_0_1"/>
    <dbReference type="OMA" id="WDAPNAV"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36838">
        <property type="entry name" value="AUXIN EFFLUX CARRIER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36838:SF3">
        <property type="entry name" value="TRANSPORTER AUXIN EFFLUX CARRIER EC FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="414"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="505" mass="52486" checksum="B72C18B70322E62B" modified="2007-05-15" version="1">MTDSAVILHRVALNAAFIAVGYALRALKILTLEDGKTVFRFATNVTLPALLLYVMTRASAVGASSGLSATVSTVSAIIPACSLLVGVGCSFGAYLAYRKSPARARGLAVGSATGVNLGMFAYPFVEAIWGVPGLALCAMWDAPNAVVVFGAAKAIFAAEQKHGDASRAVHDDGGIYDGEWLDKKKHGYGCYKYPSGATYEGQWKNNVKDGLGVYTYGKGGSYAGEFKRGRFDGTGIRVLRTGAVKAGLWEDNEFVEATTVKDCEGTIAATNAAVSTARKAAEASNLTMKDLFWKVAKFPPVIAVTLASMMNFTGIALPQTASQLVVPLANANNPIVLLTLGVLFKPAMDRMQVQAVAKFIGVKYGLGLLSAAVCTLFIPQSFALARGVIAALCVMPVPSIVMQYSAEHENDGQLAAAIVLSSQAMTLVLICCFAVVAPYIVSIDKFVFSGALLAGAVAVGVASAVGVLALKPSRVDKAKSPGVARSAPQAPLRAALSGGVKLVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S687</accession>
    <name>A4S687_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_17761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420902.1">
        <property type="nucleotide sequence ID" value="XM_001420865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S687"/>
    <dbReference type="STRING" id="436017.A4S687"/>
    <dbReference type="GeneID" id="5005079"/>
    <dbReference type="Gramene" id="ABO99195">
        <property type="protein sequence ID" value="ABO99195"/>
        <property type="gene ID" value="OSTLU_17761"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17761"/>
    <dbReference type="eggNOG" id="ENOG502S1U9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_697165_0_0_1"/>
    <dbReference type="OMA" id="LICYHER"/>
    <dbReference type="OrthoDB" id="45168at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="43411" checksum="696D513EAC6200A5" modified="2007-05-15" version="1">MGARDAASPVRSLDVARARATWTALDEAIRGDAGAWTFDDDDDDARATTSGREERDAGDAIRALGYAIVPRCANRALARRVATLARGLAARGLDPTYVFVYEDAWTLLRTIETACKSRGCFGGLIMNYDVLAWCVDPVSDGEATTAFCPHRDRQPDDSPGSFSENGDAKYATAWVALANDATPENSCLYCVPRPHDPGYYDGDDDDANAKDPLSVALDSKKAFQYVRALPCKAGDGVVFTHRLIHWGSIGEGREDRPRINISFGFACESFEPAYLTSRSRVPSFDERLALVAGQLICYHERFPPNAKELGVLKKLFDGMKSSFDDAYVRKVNKEFANAALRGENDDEVEEDALDAMLDAADDFDDDFDDFEDGVEGDAYGRVADGDDALAKRSKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6K6</accession>
    <name>A4S6K6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_29755</name>
        <name evidence="11" type="ORF">OSTLU_41670</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARR-like family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420962.1">
        <property type="nucleotide sequence ID" value="XM_001420925.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422932.1">
        <property type="nucleotide sequence ID" value="XM_001422895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6K6"/>
    <dbReference type="STRING" id="436017.A4S6K6"/>
    <dbReference type="GeneID" id="5005168"/>
    <dbReference type="GeneID" id="5006905"/>
    <dbReference type="Gramene" id="ABO99255">
        <property type="protein sequence ID" value="ABO99255"/>
        <property type="gene ID" value="OSTLU_41670"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABP01291"/>
        <property type="gene ID" value="OSTLU_29755"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048511">
        <property type="term" value="P:rhythmic process"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Bact_response_regulator"/>
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    <dbReference type="InterPro" id="IPR010402">
        <property type="entry name" value="CCT_domain"/>
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    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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        <property type="entry name" value="RESPONSE REGULATORY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44591">
        <property type="entry name" value="STRESS RESPONSE REGULATOR PROTEIN 1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="53"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="CCT" evidence="10">
        <location>
            <begin position="462"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="179"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="256"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="480"/>
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    </feature>
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        <location>
            <begin position="262"/>
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    </feature>
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        <location>
            <begin position="516"/>
            <end position="535"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="538"/>
            <end position="551"/>
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        <location>
            <position position="110"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010330"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023108"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50110"/>
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        <source>
            <dbReference type="PROSITE" id="PS51017"/>
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        <source>
            <dbReference type="EMBL" id="ABO99255.1"/>
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        <source>
            <dbReference type="EMBL" id="ABP01291.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
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    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="578" mass="61179" checksum="62871A788C9B25C5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6U2</accession>
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        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 2</fullName>
        </recommendedName>
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        <name evidence="11" type="ORF">OSTLU_25439</name>
        <name evidence="12" type="ORF">OSTLU_25920</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11 13">CCE9901</strain>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
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        <text evidence="2">Belongs to the TAF2 family.</text>
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    </dbReference>
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    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
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        <location>
            <begin position="226"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 2 Ig-like" evidence="9">
        <location>
            <begin position="482"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 2 TPR repeats" evidence="10">
        <location>
            <begin position="619"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="970"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1043"/>
            <end position="1112"/>
        </location>
    </feature>
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        <location>
            <begin position="977"/>
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        </location>
    </feature>
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        <location>
            <begin position="1075"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1099"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010937"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00017363"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01433"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF25316"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF25577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99296.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABP01251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1112" mass="121388" checksum="53D5D0F99765AF57" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S741</accession>
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    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27343</name>
    </gene>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421207.1">
        <property type="nucleotide sequence ID" value="XM_001421170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S741"/>
    <dbReference type="GeneID" id="5005536"/>
    <dbReference type="Gramene" id="ABO99500">
        <property type="protein sequence ID" value="ABO99500"/>
        <property type="gene ID" value="OSTLU_27343"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27343"/>
    <dbReference type="HOGENOM" id="CLU_1996451_0_0_1"/>
    <dbReference type="OMA" id="AMEANDQ"/>
    <dbReference type="OrthoDB" id="498430at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="125" mass="13418" checksum="7E6EED8B8F16E465" modified="2007-05-15" version="1">MSWTWDSFAKGAADAAETTRLVAIKGAKQAEIMYKERNITSTTQQFGVDCFAAMEANDQARAASLFAAAKREVDAYRADIAQLNREIDGVNVEIENVGREDAASAAPPVVRATPPNARGASLQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="112" xmlns="https://uniprot.org/uniprot">
    <accession>A4S749</accession>
    <name>A4S749_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_89073</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421393.1">
        <property type="nucleotide sequence ID" value="XM_001421356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S749"/>
    <dbReference type="STRING" id="436017.A4S749"/>
    <dbReference type="GeneID" id="5005397"/>
    <dbReference type="Gramene" id="ABO99686">
        <property type="protein sequence ID" value="ABO99686"/>
        <property type="gene ID" value="OSTLU_89073"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89073"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002848_0_0_1"/>
    <dbReference type="OMA" id="ELHCAML"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.990:FF:000002">
        <property type="entry name" value="mRNA export factor elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="408"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="655"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="13">
        <location>
            <begin position="788"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO99686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1031" mass="114210" checksum="9271BA759BDABE7F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Q2</accession>
    <name>A4S7Q2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421495.1">
        <property type="nucleotide sequence ID" value="XM_001421458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Q2"/>
    <dbReference type="STRING" id="436017.A4S7Q2"/>
    <dbReference type="GeneID" id="5005468"/>
    <dbReference type="Gramene" id="ABO99788">
        <property type="protein sequence ID" value="ABO99788"/>
        <property type="gene ID" value="OSTLU_27578"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27578"/>
    <dbReference type="eggNOG" id="KOG2273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029979_0_0_1"/>
    <dbReference type="OMA" id="MLVNHRK"/>
    <dbReference type="OrthoDB" id="271164at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07596">
        <property type="entry name" value="BAR_SNX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06865">
        <property type="entry name" value="PX_SNX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044279">
        <property type="entry name" value="SNX2A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46757:SF2">
        <property type="entry name" value="OS05G0346100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46757">
        <property type="entry name" value="SORTING NEXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="58"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="505" mass="56229" checksum="FD21852003D2803B" modified="2007-05-15" version="1">MSYGDLLAPPPSYADSVMYAQPEIQPARDVGANAVGGTTTVYLDGDDGAGDEETLQIWVSDPKIEADTSAALVGKRVTHYKITTRTTIPSYIHKEVVVWRRFRDFVALDARLSALHRGYFIPPRPEKTVVSSTGDNFIAERAIQLQHYLNRIASHSKLRLGDPLRIFLTHQDLASSLDWFNMTAGRVITTIPSDLPSSPETPQRPPIAVASPGQPRDFGRFFKELRQTVVQSTAVSAVGGVLGLDTPKPKVMEEDAAFLVEKDRVVRMENELSGMSSKATKLLTLQQKFGEAVGEFGLECLKFAKIQEEEGTRLGKYSENGLECMTAANEMRKAGNTSIKVSRVSRAATAQTAQSLEPLHDYLKIMPSVRRSISDRNESLLTLQTMLAEADRLEARIAKLTPDFTKMKKVEDLKLELDATRATGEQAKVDYKIIQDRHREEFARLEKERVAQFHAMLLNYSRVQVANAERSLSLWRGLAEEFGASADEWRTPEPEKSGEADETTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S821</accession>
    <name>A4S821_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_40586</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421685.1">
        <property type="nucleotide sequence ID" value="XM_001421648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S821"/>
    <dbReference type="STRING" id="436017.A4S821"/>
    <dbReference type="GeneID" id="5005655"/>
    <dbReference type="Gramene" id="ABO99978">
        <property type="protein sequence ID" value="ABO99978"/>
        <property type="gene ID" value="OSTLU_40586"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40586"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039068_0_0_1"/>
    <dbReference type="OMA" id="YCLPYVI"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050342">
        <property type="term" value="F:tocopherol C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010189">
        <property type="term" value="P:vitamin E biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="8">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="6">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="6">
        <location>
            <begin position="186"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="6">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37614" checksum="72936322ADE2D7D3" modified="2007-05-15" version="1">MASIARAPTTASPSARATRRRARRAATTPSASANEERTTSTFELERVVEPLIAETKTLNEGIAKFYDESSRVWEDVWGSEGGDGTHMHHGYYRRGEPVNHAKAQVDMIEESLRWAGVREVKRVLDVGCGIGGSSRHMVRKYGCEAEGVTLSPVQAARANALAKEEGVENMAKYRVADALNMPFEDGSFDFVWSMESGEHMPDKKKFVDELARVCAPGGRILIVTWCHRTLEPGQSALEPAERVLLDRICDAYYLPAWCSIADYKALAEDAGLVDIETEDWSEEVKPFWKGVIKTALTLKGVIGLLKSGAATLRGALVMPLMQTGLATGTIKFNLITMRKPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S823</accession>
    <name>A4S823_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PRPL12 Chloroplast ribosomal protein L12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PRPL12</name>
        <name evidence="5" type="ORF">OSTLU_8310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421553.1">
        <property type="nucleotide sequence ID" value="XM_001421516.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S823"/>
    <dbReference type="STRING" id="436017.A4S823"/>
    <dbReference type="GeneID" id="5005657"/>
    <dbReference type="Gramene" id="ABO99846">
        <property type="protein sequence ID" value="ABO99846"/>
        <property type="gene ID" value="OSTLU_8310"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8310"/>
    <dbReference type="eggNOG" id="KOG1715">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_0_0_1"/>
    <dbReference type="OMA" id="HARECSS"/>
    <dbReference type="OrthoDB" id="250175at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_bL12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="71"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="138" mass="13879" checksum="99F2C749E22A9AA0" modified="2007-05-15" version="1" fragment="single">KVAEIADRVCELTLIEVNELCDVLAERLGLGDMSGMMFGGGVMPAGGGGGGGGGGGGGNAAAAPAEEKTSFALKLESFDAAQKIKVIKEVRAITDLGLKEAKELVEGAPAVLKKELKKEEAEALIAKLTAVGAVAALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4S840</accession>
    <name>A4S840_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_40662</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421695.1">
        <property type="nucleotide sequence ID" value="XM_001421658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S840"/>
    <dbReference type="STRING" id="436017.A4S840"/>
    <dbReference type="GeneID" id="5005832"/>
    <dbReference type="Gramene" id="ABO99988">
        <property type="protein sequence ID" value="ABO99988"/>
        <property type="gene ID" value="OSTLU_40662"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40662"/>
    <dbReference type="eggNOG" id="KOG2323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015439_0_1_1"/>
    <dbReference type="OMA" id="TAMENTC"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="17">
        <location>
            <begin position="87"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="18">
        <location>
            <begin position="446"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO99988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="572" mass="61927" checksum="EC1F92FFEDA6CA76" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8C3</accession>
    <name>A4S8C3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rubisco LSMT substrate-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27798</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421597.1">
        <property type="nucleotide sequence ID" value="XM_001421560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8C3"/>
    <dbReference type="GeneID" id="5005679"/>
    <dbReference type="Gramene" id="ABO99890">
        <property type="protein sequence ID" value="ABO99890"/>
        <property type="gene ID" value="OSTLU_27798"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27798"/>
    <dbReference type="HOGENOM" id="CLU_052893_0_0_1"/>
    <dbReference type="OMA" id="SANETEW"/>
    <dbReference type="OrthoDB" id="10413974at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rubisco LSMT substrate-binding" evidence="4">
        <location>
            <begin position="204"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="341" mass="37862" checksum="5411FCB31E35532F" modified="2007-05-15" version="1">MRERAKGGVSAYAPFVESLYEHTPARAVETSRAARARLEGHAAAETMREYERDAEDGWRAARRTFETFPSIFSVHEFTRAAFEEALAIVRANSFEARSEDGTRARALVPMAHLLLHDTGSEVPCVKIVDGVFVINVDEHEEGDELSCSHGDYSDAETFARFGVSAFYSAEKNARNKIKFAFPSEIYSMKSLDRCGSVENIAFTDAGATEEFMCALRLASANETEWAAISKSKASVRALRKKPLSEESEIAVYEALFATLTELLNSYPSSDNEDERLLQSRTLQSAPDEERAVTIRLREKRLALSSLNAVQYAGRQQLGGLLFDKHFADVLPSPVNVRQTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8C7</accession>
    <name>A4S8C7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNL-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_40563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421744.1">
        <property type="nucleotide sequence ID" value="XM_001421707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8C7"/>
    <dbReference type="STRING" id="436017.A4S8C7"/>
    <dbReference type="GeneID" id="5005637"/>
    <dbReference type="Gramene" id="ABP00038">
        <property type="protein sequence ID" value="ABP00038"/>
        <property type="gene ID" value="OSTLU_40563"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40563"/>
    <dbReference type="eggNOG" id="KOG3277">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125166_1_0_1"/>
    <dbReference type="OMA" id="NDERHAA"/>
    <dbReference type="OrthoDB" id="512667at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF15">
        <property type="entry name" value="A_TM021B04.14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="3">
        <location>
            <begin position="102"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="181" mass="20236" checksum="D98AE09923082170" modified="2007-05-15" version="1">MSFALTLARPGRVSPFARARERSTTSACTPSSSRVARRSRAASVVLARAPSLSTRLFARRRDDVPLARARSVARVNVLGDGGTSSSDDEGEEEGRASVQLPRTRRRVQMTFTCNKCEGRTMRMINPEVLERGTMWVQCGECEVWHQIVDNLGLIFDFTGDYTELKDKIINAKRMQPPESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8F4</accession>
    <name>A4S8F4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421760.1">
        <property type="nucleotide sequence ID" value="XM_001421723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8F4"/>
    <dbReference type="GeneID" id="5005648"/>
    <dbReference type="Gramene" id="ABP00054">
        <property type="protein sequence ID" value="ABP00054"/>
        <property type="gene ID" value="OSTLU_27832"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27832"/>
    <dbReference type="HOGENOM" id="CLU_2088855_0_0_1"/>
    <dbReference type="OrthoDB" id="513226at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.210">
        <property type="entry name" value="Chaperonin-like RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038052">
        <property type="entry name" value="Chaperonin_RbcX_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158615">
        <property type="entry name" value="RbcX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673133" evidence="1">
        <location>
            <begin position="17"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="117" mass="13069" checksum="9F95503A654AD9AE" modified="2007-05-15" version="1">MISRLHTLVGVRIVMAQLDGQGNECSEDVNQSSVTAAMLKQMETTPLVGTGSEFIESLMRSEDADVRLAATRVIEVRREFGDEFDWDEMKKSLLVDLSQYRLEMLRTHAAKSFDGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8R0</accession>
    <name>A4S8R0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Centromere protein S</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27937</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TAF9 family. CENP-S/MHF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421804.1">
        <property type="nucleotide sequence ID" value="XM_001421767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8R0"/>
    <dbReference type="GeneID" id="5005806"/>
    <dbReference type="Gramene" id="ABP00098">
        <property type="protein sequence ID" value="ABP00098"/>
        <property type="gene ID" value="OSTLU_27937"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27937"/>
    <dbReference type="HOGENOM" id="CLU_2310845_0_0_1"/>
    <dbReference type="OrthoDB" id="1872155at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071821">
        <property type="term" value="C:FANCM-MHF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22919">
        <property type="entry name" value="HFD_CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029003">
        <property type="entry name" value="CENP-S/Mhf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF0">
        <property type="entry name" value="CENTROMERE PROTEIN S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15630">
        <property type="entry name" value="CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11297" checksum="FDEE0AF955F17305" modified="2007-05-15" version="1">MGDVGDGDGDANLFEHLKSHVVRVAERVARSHDKSLTPKTAHALSELSYELTKSIARDVRAYANHADRDVVGVKDCDLRARRLRQLVERRRRAMDEDGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S904</accession>
    <name>A4S904_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_4415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421848.1">
        <property type="nucleotide sequence ID" value="XM_001421811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S904"/>
    <dbReference type="STRING" id="436017.A4S904"/>
    <dbReference type="GeneID" id="5006022"/>
    <dbReference type="Gramene" id="ABP00142">
        <property type="protein sequence ID" value="ABP00142"/>
        <property type="gene ID" value="OSTLU_4415"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4415"/>
    <dbReference type="eggNOG" id="KOG0616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_5_1"/>
    <dbReference type="OMA" id="EEWVQFY"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="5"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="266" mass="30687" checksum="71B129C6CB8C5B17" modified="2007-05-15" version="1" fragment="single">TFRDFIILRELGRGLCGTVYLAKYRFTDQLVAFKVMRKQKLIDVGEIRHAVREREVHATINQGPFIDKLLHAYQDKWALYLVLEYAPCGDLFQAMNYHGLPTLQDAKMYTTQCALALDYIHRCGYVYRDLKPENILLDVNGSVRLADFGMAKKLDDGERAFTICGTAQYMSPEVLTHRGCRFEADIWALGVLIYELCSGGTPFGADKDSRQELYRRLMHHRNESMTFPPWFDADTCSIVKSFLHEDETQRLGYGGAFSLIFDHPWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S936</accession>
    <name>A4S936_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421997.1">
        <property type="nucleotide sequence ID" value="XM_001421960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S936"/>
    <dbReference type="GeneID" id="5006037"/>
    <dbReference type="Gramene" id="ABP00291">
        <property type="protein sequence ID" value="ABP00291"/>
        <property type="gene ID" value="OSTLU_28063"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28063"/>
    <dbReference type="HOGENOM" id="CLU_858911_0_0_1"/>
    <dbReference type="OMA" id="VFANECI"/>
    <dbReference type="OrthoDB" id="10452322at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="33837" checksum="F3E809DEFD0BD8BE" modified="2007-05-15" version="1">MAGARRAPSKRSSSKKSARSTRSSPKSKLPSLPKIGNPLTTLVNLNVLGNAKATATMLTSVSGLKTFLERLGAYGAATSIAYAGVPELGGRGTAAMFKSLGLKGASGPLAPVGAAWFGAHWSFVQFLIGFGAILGIGSNSDIPALFTAMSLFLCGNTMIAGSSHGVRDVFIRNAMAFKYSNAILLLLTTRKARGYFSSKQAAALRKLAIAVPGLMMSFLMMQGSSMAKFTAAGMTGPGVLGPVAGLIFHPLHHVVSTCVALGYISGYSTRRAALFLCLELLIVATSLAPQMVQPWGRALSAMHLGAAMVFMRECTPTNSFIPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9W6</accession>
    <name>A4S9W6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC(ATP-binding) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_42103</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family. CPR flippase (TC 3.A.1.211) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422137.1">
        <property type="nucleotide sequence ID" value="XM_001422100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9W6"/>
    <dbReference type="STRING" id="436017.A4S9W6"/>
    <dbReference type="GeneID" id="5006301"/>
    <dbReference type="Gramene" id="ABP00454">
        <property type="protein sequence ID" value="ABP00454"/>
        <property type="gene ID" value="OSTLU_42103"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42103"/>
    <dbReference type="eggNOG" id="KOG0059">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_19_1_1"/>
    <dbReference type="OMA" id="WKNWIVL"/>
    <dbReference type="OrthoDB" id="496966at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC transporter A family member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP binding cassette subfamily A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
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        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="624"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="668"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="697"/>
            <end position="717"/>
        </location>
    </feature>
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        <location>
            <begin position="296"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="891"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008526"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1226" mass="135946" checksum="7F78FEBF72E84C38" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAE0</accession>
    <name>A4SAE0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_47987</name>
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    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
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    </dbReference>
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        <location>
            <begin position="57"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="94" mass="10779" checksum="81E1C6123F57C06E" modified="2007-05-15" version="1" fragment="single">LRRLAAGPVWSTARRFDAVRRRRRVRRRARRDGEADIHRVELLARSRGHDRAVGVDGVLGDGVSRRDDERRSRAAVRDARRGRLENGKDDGDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAE7</accession>
    <name>A4SAE7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_18863</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SNAP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422423.1">
        <property type="nucleotide sequence ID" value="XM_001422386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAE7"/>
    <dbReference type="STRING" id="436017.A4SAE7"/>
    <dbReference type="GeneID" id="5006431"/>
    <dbReference type="Gramene" id="ABP00740">
        <property type="protein sequence ID" value="ABP00740"/>
        <property type="gene ID" value="OSTLU_18863"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18863"/>
    <dbReference type="eggNOG" id="KOG1586">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046329_0_2_1"/>
    <dbReference type="OMA" id="WSVKEYL"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
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        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF8">
        <property type="entry name" value="ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="303" mass="32833" checksum="8431D6FF145B359B" modified="2007-05-15" version="1">MGDDDLARGDALCAAAAKKLRSVGFFSAITGANRHEEAAELYERAATSFKLAKSWRRAADAYEALATCRATTKETHDAASAHVDCAQMLKKCGANEEAIGHYREASNAYARLGRLAQAAKHLKEIGETYESLGTAEGDERAVEAFSSAADLYDGEGDSGRTTGNNCKLKAATLLASKLDRFEEATEIFEDVGRASLNNNLLRFSVKGYFLQAGICRLCWNDAVGVLNACERYEESDPAFASSRERDLLVNCAKAFEAGDQDAFSSAVAEFDSMSRLDGWKTTMLLKAKKRIVAAVEAEEDDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAJ6</accession>
    <name>A4SAJ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_4341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422444.1">
        <property type="nucleotide sequence ID" value="XM_001422407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAJ6"/>
    <dbReference type="STRING" id="436017.A4SAJ6"/>
    <dbReference type="GeneID" id="5006459"/>
    <dbReference type="Gramene" id="ABP00761">
        <property type="protein sequence ID" value="ABP00761"/>
        <property type="gene ID" value="OSTLU_4341"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4341"/>
    <dbReference type="eggNOG" id="KOG0585">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="LSASQCC"/>
    <dbReference type="OrthoDB" id="497410at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="243" mass="27440" checksum="032D2AE87D96A6C6" modified="2007-05-15" version="1" fragment="single">YAVKELNKRKLANVRVGSSRTLLDAAEEEIRMQSECRCANVVQAYEWVNDARESTAKIVMEYCERGSVVDDERDTFERFDLSDVKAIARDILRALRTCHARNIAHYDVKPQNIFASASGAYKLGDFGCATRLERTHEFVGKTPGTPAFTAPECCEGEPCDGFKADVWALGMTLHALATGRYFYQADGAWDTYQKVLRESVDLGEIARLGDDGFTDFMTRVLERDPNERLTARQALKHPWITPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAR9</accession>
    <name>A4SAR9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422483.1">
        <property type="nucleotide sequence ID" value="XM_001422446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAR9"/>
    <dbReference type="GeneID" id="5006713"/>
    <dbReference type="Gramene" id="ABP00800">
        <property type="protein sequence ID" value="ABP00800"/>
        <property type="gene ID" value="OSTLU_18953"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18953"/>
    <dbReference type="eggNOG" id="ENOG502S6G1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_856167_0_0_1"/>
    <dbReference type="OMA" id="YHLAWIP"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF8">
        <property type="entry name" value="HAD FAMILY HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="35704" checksum="2E9B21EF2B95D90C" modified="2007-05-15" version="1">MATARIARVAPARADARARRARGARASSTAPSTPARATRRRAEAPRRDERLEVITFDLDDTLWPTTPVVNAANEALIEWCSARLGGRFPRTARVHATMKRIREQRECEAAARGTTAEPMSYAAIRIAGATRAAIECGIPESDAVATVARGYHLAWIPMRNAMARELVYPGAAEALRAIRERHPGVAVGSITNGFGSAAGAGLGEFFDFEISAEALIDEHMVHGEMARKPNAYPFQLAMGIAIADHGYSGDADSWTHVGDDVLNDCYCAKQFDFKTVHVCDPTTKPYESGGGAPYAEKSLRGGVEANSDAVVDGVISHVRELPELLDRWYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBB8</accession>
    <name>A4SBB8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_43732</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the small GTPase superfamily. SAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422590.1">
        <property type="nucleotide sequence ID" value="XM_001422553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBB8"/>
    <dbReference type="STRING" id="436017.A4SBB8"/>
    <dbReference type="GeneID" id="5006805"/>
    <dbReference type="Gramene" id="ABP00907">
        <property type="protein sequence ID" value="ABP00907"/>
        <property type="gene ID" value="OSTLU_43732"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43732"/>
    <dbReference type="eggNOG" id="KOG0077">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040729_6_0_1"/>
    <dbReference type="OMA" id="GLWNKHG"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00879">
        <property type="entry name" value="Sar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000261">
        <property type="entry name" value="GTP-binding protein SAR1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006687">
        <property type="entry name" value="Small_GTPase_SAR1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45684">
        <property type="entry name" value="RE74312P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51422">
        <property type="entry name" value="SAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 15" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 15" id="KW-0333">Golgi apparatus</keyword>
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        <location>
            <begin position="28"/>
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        </location>
        <ligand>
            <name>GTP</name>
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        <location>
            <position position="30"/>
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        <ligand>
            <name>Mg(2+)</name>
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            <name>GTP</name>
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        </source>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606687-1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606687-2"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABP00907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="193" mass="22192" checksum="8384D5161C1C341C" modified="2007-05-15" version="1">MVFFFDWFYDVLASLGLWQKNAKILFLGLDNAGKTTLMHMLKDERLAQHQPTQYPTSEELSIGQIRFKAFDLGGHEVARRVWKDYYAKVDAIVFLVDAVDKERFMESKKELDSLLGDDSLGNVPFLILGNKIDIPHAASEEELRHCLGLTNYTTGKGKVNLENTNMRPIEVFMCSVVRRMGYAEGFRWVSQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQC3</accession>
    <name>A4RQC3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyltransferase family 92 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_85990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQC3"/>
    <dbReference type="STRING" id="436017.A4RQC3"/>
    <dbReference type="GeneID" id="4999743"/>
    <dbReference type="Gramene" id="ABO93653">
        <property type="protein sequence ID" value="ABO93653"/>
        <property type="gene ID" value="OSTLU_85990"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_85990"/>
    <dbReference type="eggNOG" id="ENOG502SCIT">
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    </dbReference>
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    <dbReference type="OMA" id="TRIYEPM"/>
    <dbReference type="OrthoDB" id="433309at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030244">
        <property type="term" value="P:cellulose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="KOBITO1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46701">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE KOBITO 1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE KOBITO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="40273" checksum="D62C886C4899989D" modified="2007-05-15" version="1">MYQVRRKGVSHNRLIALTFVIVVVATVVLSSAPRRPSRGGVAVASTCASSSRQLTDWLEYHRAIGVTRFYIFEEGMGTTAGRWSPDVYVFSRKTADENQKNSPSRFAKWLAPYASGNSTCGANALFVRQTLNLELAIARAKKDGIEWLLHVDVDELVYPAGSSTLDLRDVLARQSPHIDRVVFPNYEAVPERPSYELNEPNTFKSVTLFKRNHLHIDTATYARFAQSARRDNPNFFLAYANGKSACRVSSPGLRPNGAHRFKTKGGGKEVTTSESAILHYPFVSAARARERAHRCDCTDVKECSMLAFDLVLANKVRGEAADFESWFDERVVENNSTRREALLKAGVYARIHAPTLLIGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQP8</accession>
    <name>A4RQP8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_92084</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415772.1">
        <property type="nucleotide sequence ID" value="XM_001415735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQP8"/>
    <dbReference type="GeneID" id="4999838"/>
    <dbReference type="Gramene" id="ABO94064">
        <property type="protein sequence ID" value="ABO94064"/>
        <property type="gene ID" value="OSTLU_92084"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92084"/>
    <dbReference type="eggNOG" id="KOG0768">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_621729_0_0_1"/>
    <dbReference type="OMA" id="YTETDAY"/>
    <dbReference type="OrthoDB" id="10253709at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="131"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="244"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="337"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="441" mass="48038" checksum="A6D6110E50126532" modified="2007-05-15" version="1">MEARAEGFGSASSGVLYNPKRGVELENLLKLDEKARNRKASVLTRGNIDLLLQELNALQAVNEEALEQVDAELALLAAKNLEGQLSEYTETDAYANLSDQKKRLVNKRSNEASLQRRLKERKVIFGRLAAQGPVVVYGAALVASIVSNATMHPLDTIKVRKISLRQKKSKEVGASVDLSVDESADEIRGYDPTWDEIVGEGGVVSLYDGLSSNLFKEGIPLALYLGLYEYAKDILLQVDVMRPHPIVIYLIAGGFGEFFASILRLPAEAVKNGTQIGMSIPEALETNVLTPAARKNLFKCWKVALLRDIPFGGIQLAVFEYLKLLLVVASIQALDPDAPLTEALFGAFGGVCGAIFTTPVDVVITRMINERKSNADAGLPEDAPGTSPIDTALGVYSDSGLPGFFVGAKERVLYWGPAISIFLTVYCRIRQYYLPDIDISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="114" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQY5</accession>
    <name>A4RQY5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_28827</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415471.1">
        <property type="nucleotide sequence ID" value="XM_001415434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQY5"/>
    <dbReference type="STRING" id="436017.A4RQY5"/>
    <dbReference type="GeneID" id="4999624"/>
    <dbReference type="Gramene" id="ABO93763">
        <property type="protein sequence ID" value="ABO93763"/>
        <property type="gene ID" value="OSTLU_28827"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28827"/>
    <dbReference type="eggNOG" id="KOG1375">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015718_1_1_1"/>
    <dbReference type="OrthoDB" id="563915at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000005">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="14">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="15">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="429"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO93763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="444" mass="49456" checksum="DDAE734FE106319C" modified="2007-05-15" version="1">MREIVHIQGGQCGNQIGAKFWEVICDEHGIGADGTYIGDSDLQLERVNVYYNEANGGRYVPRAVLMDLEPGTMDSVRSGPYGQIFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVMDVVRKEAESCDCLQGFQVAHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVVPSPKVSDTVVEPYNATLSVHQLVENADECVVLDNEALYDICFRTLKLTNPTFGDLNHLISAVMSGITCCLRFPGQLNADLRKLAVNLVPFPRLHFFMVGFAPLTSRGAQQYRALSVPEITAQMWDAKNMMCAADPRHGRYLTASALYRGRMSTKEVDEQLLNVQNKNSAYFVEWIPNNVKSSVCDIPPKGLKMSATFVGNTTAIQEMFKRVSEAFTSMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATVDDDGDYDEDEDGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR25</accession>
    <name>A4RR25_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MHD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415493.1">
        <property type="nucleotide sequence ID" value="XM_001415456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR25"/>
    <dbReference type="STRING" id="436017.A4RR25"/>
    <dbReference type="GeneID" id="4999429"/>
    <dbReference type="Gramene" id="ABO93785">
        <property type="protein sequence ID" value="ABO93785"/>
        <property type="gene ID" value="OSTLU_28866"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28866"/>
    <dbReference type="eggNOG" id="ENOG502QT32">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_294119_0_0_1"/>
    <dbReference type="OMA" id="ENQHNHY"/>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057984">
        <property type="entry name" value="PATROL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008528">
        <property type="entry name" value="unc-13_homologue"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31280">
        <property type="entry name" value="PROTEIN UNC-13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31280:SF2">
        <property type="entry name" value="PROTEIN UNC-13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25761">
        <property type="entry name" value="TPR_PATROL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD2" evidence="1">
        <location>
            <begin position="744"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="917" mass="100593" checksum="D7CF0CB2F94EC80B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRQ3</accession>
    <name>A4RRQ3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415941.1">
        <property type="nucleotide sequence ID" value="XM_001415904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRQ3"/>
    <dbReference type="GeneID" id="4999467"/>
    <dbReference type="Gramene" id="ABO94233">
        <property type="protein sequence ID" value="ABO94233"/>
        <property type="gene ID" value="OSTLU_13914"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13914"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_536817_0_0_1"/>
    <dbReference type="OMA" id="IHRDPYL"/>
    <dbReference type="OrthoDB" id="47172at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="357"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="508" mass="55263" checksum="114C903167F7B653" modified="2007-05-15" version="1">MATADAWDAFGRDDGARATTARARDDARDARAAATHAFFENARELWSGARARDGATRDARAVAEEIARAHDAGWASTAAELEEFAPSGRRARDALARCAANARAETWDACARWAKRTIEACGEQLGRGNWPVSGFLEAHTLAHGWLVVAGVAATASDAGEDVDEGALEDDPTASAACRGAEWSARERLGRIGLDLLTATTLFERGCVPTWCASAILLVERAFQPDDAEGRRAFPLNSAIPTTLPMSGVPTIEPSRQIHFEDARSLTAPRFYADFVASETPVVIRGHLDEDGENWAALDVFKNLDAFEKYADTIVPVEYGTAFDSHGVGITTLGSFARDFLAPSNAAHDGAPTSDKVAYVSQHPIFHQIPELQSTFTVIPYTLGRLRVETSAVNLWLGTAGTRTAIHRDPYLNLLCQVSGYKYVRIYAVSETPHLYVADTDTLRGSNVNNFTRSPVDPESPTVSREHPRALAAKFLETILAPGDVLFMPKGHWHYVRSLTSSVSVNFWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS15</accession>
    <name>A4RS15_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">riboflavin kinase</fullName>
            <ecNumber evidence="2">2.7.1.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="2"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415661.1">
        <property type="nucleotide sequence ID" value="XM_001415624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS15"/>
    <dbReference type="SMR" id="A4RS15"/>
    <dbReference type="STRING" id="436017.A4RS15"/>
    <dbReference type="GeneID" id="4999795"/>
    <dbReference type="Gramene" id="ABO93953">
        <property type="protein sequence ID" value="ABO93953"/>
        <property type="gene ID" value="OSTLU_29210"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29210"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048437_3_1_1"/>
    <dbReference type="OMA" id="NACIAVP"/>
    <dbReference type="OrthoDB" id="498027at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07505">
        <property type="entry name" value="HAD_BPGM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.30:FF:000005">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase domain-containing protein 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="8">
        <location>
            <begin position="147"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO93953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="289" mass="31894" checksum="C427EE9F499B5F91" modified="2007-05-15" version="1">MPGARRLLEHLRARGVPFGLATSTPATYLKEKMRGHEDVLAMMDCVVTGCMVNRGKPDPEIFVAASAKLGAEASACVVLEDTPVGCEAARRAGCKTIAIPSIRDRKCFEAWSDVVLHSLYDLELEKFGLPAFDDWLPVGDGSADRVLPVPTIEMRGPVVKGFGRGSTQLGIPTANLDIVPLKHQVDSLAPGIYLGFASIRGETHKMVMSIGWNPYFDNSKKTIEPWLLHEFESDFYGEELSLVVVGYIRPEADFTTLEALVERIHRDAEVARVVLEREPFVGKRQMLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS29</accession>
    <name>A4RS29_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_1868</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416008.1">
        <property type="nucleotide sequence ID" value="XM_001415971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS29"/>
    <dbReference type="STRING" id="436017.A4RS29"/>
    <dbReference type="GeneID" id="5000025"/>
    <dbReference type="Gramene" id="ABO94300">
        <property type="protein sequence ID" value="ABO94300"/>
        <property type="gene ID" value="OSTLU_1868"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1868"/>
    <dbReference type="eggNOG" id="KOG2481">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019619_1_0_1"/>
    <dbReference type="OMA" id="QKVTWIV"/>
    <dbReference type="OrthoDB" id="10264910at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000232">
        <property type="term" value="P:regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
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        <property type="entry name" value="BRCT_pescadillo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03028">
        <property type="entry name" value="Pescadillo"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010613">
        <property type="entry name" value="PES"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221">
        <property type="entry name" value="PESCADILLO - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221:SF6">
        <property type="entry name" value="PESCADILLO HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06732">
        <property type="entry name" value="Pescadillo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="310"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="437"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="542"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="477"/>
        </location>
    </feature>
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        <location>
            <begin position="478"/>
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        </location>
    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="565" mass="64825" checksum="FA1B6BC7D8241783" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS37</accession>
    <name>A4RS37_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415674.1">
        <property type="nucleotide sequence ID" value="XM_001415637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS37"/>
    <dbReference type="STRING" id="436017.A4RS37"/>
    <dbReference type="GeneID" id="4999998"/>
    <dbReference type="Gramene" id="ABO93966">
        <property type="protein sequence ID" value="ABO93966"/>
        <property type="gene ID" value="OSTLU_92228"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92228"/>
    <dbReference type="HOGENOM" id="CLU_112219_0_0_1"/>
    <dbReference type="OMA" id="FHEEHAN"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF123">
        <property type="entry name" value="OS04G0645500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23822" checksum="2554C80A9EC76B71" modified="2007-05-15" version="1">MVWHSCLVLGRWFSRAEVARWFADTFAGATRRFLEIGGGNCIAGMAFAAQIGDGKWDVVLTDADAEAVRNTMYNASKQDSLRNRSVRCETLDWNADEDFCARHGARTFDVIIGTDVVHEESMAPGVLRALDRYLAPDGLAIVVNPAPHSRGGAASFQKLLDERAWRVETHHGISNSILCVGIEEECEDVPLDFYVIRRRETIDLDLPPMQNLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS93</accession>
    <name>A4RS93_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_92247</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415704.1">
        <property type="nucleotide sequence ID" value="XM_001415667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS93"/>
    <dbReference type="GeneID" id="4999706"/>
    <dbReference type="Gramene" id="ABO93996">
        <property type="protein sequence ID" value="ABO93996"/>
        <property type="gene ID" value="OSTLU_92247"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92247"/>
    <dbReference type="HOGENOM" id="CLU_761515_0_0_1"/>
    <dbReference type="OMA" id="PCCCDSE"/>
    <dbReference type="OrthoDB" id="10686156at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001212">
        <property type="entry name" value="Somatomedin_B_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00524">
        <property type="entry name" value="SMB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50958">
        <property type="entry name" value="SMB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMB" evidence="3">
        <location>
            <begin position="341"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="387" mass="41599" checksum="93D55D7CF806D900" modified="2007-05-15" version="1" fragment="single">VDNRCVETLLSTLANAIEVRTFTSLVLHDELYSRRFQTISGHAMTTVFAPKDIAWYHRNLTTPARATAAERSDIIAAHVVMSSSNHALRHGQRLITDLGVKEVMVSASSDTVAHSLVAIETGRRRIVLGGFPVKETRCRVYGTATFFWKECLPSMYTEIIVKSSDARLGVESKFSRAEQSIGPIFASLESRADGDDAFSEEDLDFEEEYVRALLFDEIIAPSSSSSSSSSAFASNSNVHGAIVDSARRSSNGIVLIVDGTLFPRRLDRVPAPQANGSSSPIPSRPPPTPTPQFLSPPSPPAQRPPPPILGSFNPIYWQTRPPPPSATAGSAREPPPSPPPSKGSCLAVLPNICGLCDFTDDAAPCCCDSECAQTGDCCSDYAVVCLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSL0</accession>
    <name>A4RSL0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vesicle transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_92319</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416475.1">
        <property type="nucleotide sequence ID" value="XM_001416438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSL0"/>
    <dbReference type="STRING" id="436017.A4RSL0"/>
    <dbReference type="GeneID" id="5000088"/>
    <dbReference type="Gramene" id="ABO94768">
        <property type="protein sequence ID" value="ABO94768"/>
        <property type="gene ID" value="OSTLU_92319"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92319"/>
    <dbReference type="eggNOG" id="KOG2887">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086833_0_0_1"/>
    <dbReference type="OrthoDB" id="498287at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF36">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SFT2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="220" mass="22801" checksum="AA77B65BA36D2F4F" modified="2007-05-15" version="1">MRASVAPVGDRPPSPSFADDWRAFADGASAQFENLSDRARALARRTSQGARATTAALQSLTPERVAWFLALSATSALMYALAFVVGAPTLAIAPAKFGLCVSAASASGVCATGALRGAQAQVTHMLSEERAVTSVVMVTTVVMTVRAAAYRHAYAQTVFWSACQTCAVGYYQVSYFPYGAQGFRTVCATAWQIAQPVMGACARAIGFAASSRGGGGALPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSS9</accession>
    <name>A4RSS9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription factor IIa large subunit 3, TFIIA3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Tf2al</name>
        <name evidence="6" type="ORF">OSTLU_119594</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIA subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416196.1">
        <property type="nucleotide sequence ID" value="XM_001416159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSS9"/>
    <dbReference type="STRING" id="436017.A4RSS9"/>
    <dbReference type="GeneID" id="5000119"/>
    <dbReference type="Gramene" id="ABO94489">
        <property type="protein sequence ID" value="ABO94489"/>
        <property type="gene ID" value="OSTLU_119594"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119594"/>
    <dbReference type="eggNOG" id="KOG2652">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030027_2_1_1"/>
    <dbReference type="OMA" id="NNVRQDF"/>
    <dbReference type="OrthoDB" id="6275927at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07976">
        <property type="entry name" value="TFIIA_alpha_beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004855">
        <property type="entry name" value="TFIIA_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03153">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01371">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="182" mass="20188" checksum="86FF641138442339" modified="2007-05-15" version="1">MEIASKYQEIIREVIKNVSAEFTAEHVNGEVLKQLEKSWEHKLLQSGALSVNSGLKTAPIIPHRGDACSKSIDEDDNKLTTGTSELQEVGHAAPNPKDETGTKRKRETDKPAVPDLGQDEVISTDSEDDNLETEPVTSNLVLSQFEKVGRTKNKWKCAFRDGVMLLNGTEYVFGKATAEFLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSZ4</accession>
    <name>A4RSZ4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thylakoid lumenal 30 kDa protein, probable</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Tl30</name>
        <name evidence="2" type="ORF">OSTLU_119521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416158.1">
        <property type="nucleotide sequence ID" value="XM_001416121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSZ4"/>
    <dbReference type="STRING" id="436017.A4RSZ4"/>
    <dbReference type="GeneID" id="5000449"/>
    <dbReference type="Gramene" id="ABO94451">
        <property type="protein sequence ID" value="ABO94451"/>
        <property type="gene ID" value="OSTLU_119521"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119521"/>
    <dbReference type="eggNOG" id="ENOG502QVAW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078654_0_0_1"/>
    <dbReference type="OMA" id="WSEITPY"/>
    <dbReference type="OrthoDB" id="496416at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF38">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="1">
        <location>
            <begin position="173"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="267" mass="29560" checksum="4BA9EACCCA107628" modified="2007-05-15" version="1">MNVRITQRTAFLTLAPSRSTAFNGRKACSNRFTRIARKIQASLDLTEDMERIVSRRYVVTSTLVIGQLTRALPAKAVMGMTAGRVPGFAKADTNGFRVYTRPEAKSGGHGVGWSEITPYSFQANESWRETPVSIADPAGTEIDAKFVSDSDGELKIILAPILRFSDKGDLDTIDIKELVSLNAFIKGFGPELLGNPIQDENILSAEEIQVKDRTYYIYELANHSLVSATTWNKRVYICAITCNSLQWRKSKSNNISVLKSFQVLVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTJ4</accession>
    <name>A4RTJ4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416064.1">
        <property type="nucleotide sequence ID" value="XM_001416027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTJ4"/>
    <dbReference type="GeneID" id="5000514"/>
    <dbReference type="Gramene" id="ABO94356">
        <property type="protein sequence ID" value="ABO94356"/>
        <property type="gene ID" value="OSTLU_29858"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29858"/>
    <dbReference type="HOGENOM" id="CLU_726445_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="381" mass="40128" checksum="C107AE8D838BFFAA" modified="2007-05-15" version="1">MTIERAQELMRSVRALVNATVGGIASARAEEGFAAALAALETEAANANATAAEAAMRASARGEYGQALDILDDILEDFVNATASARGVGELGEALRALGEAAEAASEAKDDESEGASVGDGEDASESDGRESSSSNDASTPKAKSETKEEDDAAKQAALIKKLEEENAALRAEQLKAENAALRKKNAELAAAEENETAKTRVDADDDENQAKEDGDDDDHGDKEDEAPEAAPFQGLSEDANDESAPAPKKSVAGATFNAAVSVHSQSPWLWYSISFILLAVVVTSYAHSHLEAAANERPASSLELGASIVRAEKNVSAKEIGREMSVNDEFWKSSRPSSPTRDVGRGTGRDSGSAGRRVGRRVVQQRGPMTAEERAFYDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTM2</accession>
    <name>A4RTM2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_29825</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416291.1">
        <property type="nucleotide sequence ID" value="XM_001416254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTM2"/>
    <dbReference type="STRING" id="436017.A4RTM2"/>
    <dbReference type="GeneID" id="5000359"/>
    <dbReference type="Gramene" id="ABO94584">
        <property type="protein sequence ID" value="ABO94584"/>
        <property type="gene ID" value="OSTLU_29825"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29825"/>
    <dbReference type="eggNOG" id="ENOG502QSMF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069245_3_0_1"/>
    <dbReference type="OMA" id="NWRLLYT"/>
    <dbReference type="OrthoDB" id="189024at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="4">
        <location>
            <begin position="58"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="242" mass="25975" checksum="43DFC500289CD87C" modified="2007-05-15" version="1">MNVAPRSIGARTRGGTASSSSANTPKLTQKLTTSTTSTARKTLTRATASAPDAQAREDAKRALLSAIEPLERGVKASDEEKAHVDALATALEALNPNPKSLAAPCINGEWELVYTTSASILGTKKPAFLRPSGKIYQTIDAESLRARNRETWPFYNAVAAELTPTSDSAVKVQFKKFFVFGGLIKVTAPERARGALDITYVDDEVRVSRGDKGNLFVLIMHDNEKRLPGEENASGSLKVLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTR1</accession>
    <name>A4RTR1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">fructose-bisphosphatase</fullName>
            <ecNumber evidence="6">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_30353</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the FBPase class 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="6"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416538.1">
        <property type="nucleotide sequence ID" value="XM_001416501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTR1"/>
    <dbReference type="STRING" id="436017.A4RTR1"/>
    <dbReference type="GeneID" id="5000652"/>
    <dbReference type="Gramene" id="ABO94831">
        <property type="protein sequence ID" value="ABO94831"/>
        <property type="gene ID" value="OSTLU_30353"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30353"/>
    <dbReference type="eggNOG" id="KOG1458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039977_1_0_1"/>
    <dbReference type="OMA" id="RCMAVGT"/>
    <dbReference type="OrthoDB" id="10256725at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000002">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000001">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006778">
        <property type="entry name" value="PRK09293.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF1">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="14">
        <location>
            <begin position="48"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="15">
        <location>
            <begin position="249"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO94831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="380" mass="40731" checksum="FFF6899D02558200" modified="2007-05-15" version="1">MSAATSACARAIVATKKTTAARRAGKSATRATPRSVAARAGGAGTPFTTWILQQEMEEKIDGELAVVLSSIGLACKQIASLVQRAGLQGMTGLAGETNVQGEDQKKLDVISNDVFCDVLRQTGRTGVIASEEEDVPVAVEETFGGNYVVVFDPLDGSSNIDAAVSTGSIWGIYESDSTCIPDFGTEDAAKIEEKCVMNVCQPGNNLLCAGYCMYSSSTILVLTLGEGVYGFTLDPTVGEFIMSHDNIKVPESGKIYSFNEGNYDMWTPGLKKYMDSLKTGGAEQGTKPYSARYIGSLVGDFHRTILYGGIYGYPGDSKNPNGKLRLLYECAPMSFIAEQAGGMGSTGKERVLDVVPEKFHQRVPFFTGSKKEVQYLESFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTU7</accession>
    <name>A4RTU7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_3562</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416558.1">
        <property type="nucleotide sequence ID" value="XM_001416521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTU7"/>
    <dbReference type="STRING" id="436017.A4RTU7"/>
    <dbReference type="GeneID" id="5000677"/>
    <dbReference type="Gramene" id="ABO94851">
        <property type="protein sequence ID" value="ABO94851"/>
        <property type="gene ID" value="OSTLU_3562"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3562"/>
    <dbReference type="eggNOG" id="KOG1320">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_2_0_1"/>
    <dbReference type="OMA" id="IMSPEGY"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010206">
        <property type="term" value="P:photosystem II repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000001">
        <property type="entry name" value="Periplasmic serine protease DegS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051201">
        <property type="entry name" value="Chloro_Bact_Ser_Proteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343:SF2">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343">
        <property type="entry name" value="PEPTIDASE S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="218"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="329" mass="34608" checksum="08A2EF5B0D596169" modified="2007-05-15" version="1" fragment="single">ERETVRLFNNAKASVVYITNVAVRRDAFTLNLTEQPQGAGSGIVWDDKGHIVTNYHVIDKANQLKVSFLPNKGGVQNQKTYDAAIVGFDDDKDIAVLQVNDPEALREMKPLVIGTSGDSMVGQRVFAIGNPFGLDHTLTTGIISGLGREIQSGNTGRPIDGIIQTDAAINPGNSGGPLLNSSGQLIGINTAIYSASGTSSGVGFALPSDMVSGIVDQIIRYGRVTRPILGVSFAPDGALDQLGLGGVLVLDARAGGPAARAGVRSTTRDESGRLILGDIIIELAGEQIQDSSDLYRTLDKLSVGETVDVTLLRGVDKVSARVTLDDVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV24</accession>
    <name>A4RV24_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_14781</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417063.1">
        <property type="nucleotide sequence ID" value="XM_001417026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV24"/>
    <dbReference type="STRING" id="436017.A4RV24"/>
    <dbReference type="GeneID" id="5000830"/>
    <dbReference type="Gramene" id="ABO95356">
        <property type="protein sequence ID" value="ABO95356"/>
        <property type="gene ID" value="OSTLU_14781"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14781"/>
    <dbReference type="eggNOG" id="KOG0117">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_922542_0_0_1"/>
    <dbReference type="OMA" id="CAERAMK"/>
    <dbReference type="OrthoDB" id="3800936at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21245">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="34"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="229"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="302" mass="33145" checksum="8089EE92ADFE4468" modified="2007-05-15" version="1">MDEDDAYDFDERRSVLLESDATDALIAGKPGRETEVFVKGIAAEASEKDVHAALRECGAESGATGFELVTDRTTGTHRGYAFARYDSRESAANAVAAIAKAECEVKKMKITASVKPSKYRVMVTGLRKDATREEIVEALRSRGAGLEFFALSRPRSAKKNAENAVVESGDHNGGRGWASFYNEACAERFMKNMAANREEKLPVADDKDKRGLVCEFVGPRPQKKEIEIKTLHVTEMNEANATDQGLREAFERYGTILGTQIMEKDRTRGWVFYDSAESVEKALAECEPVEGAAEASTAPPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV65</accession>
    <name>A4RV65_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417085.1">
        <property type="nucleotide sequence ID" value="XM_001417048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV65"/>
    <dbReference type="GeneID" id="5001125"/>
    <dbReference type="Gramene" id="ABO95378">
        <property type="protein sequence ID" value="ABO95378"/>
        <property type="gene ID" value="OSTLU_30863"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30863"/>
    <dbReference type="HOGENOM" id="CLU_1680844_0_0_1"/>
    <dbReference type="OrthoDB" id="10632078at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="157" mass="17524" checksum="3B61500F66C6619C" modified="2007-05-15" version="1">MVDESGVNAEMATERASAIEEATFWADAAREARAALPTGWDVREEQIEAIVRGRDRVVLIVTSDNDFKLAMDYAAAKGVVVVVLGNLVDFSSAQRSRASDPKKYWDALRVECERRPLSRLKLVQSCDCALIWDPYVENIAGVWFPARGSGMGRWYHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV85</accession>
    <name>A4RV85_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416798.1">
        <property type="nucleotide sequence ID" value="XM_001416761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV85"/>
    <dbReference type="GeneID" id="5001117"/>
    <dbReference type="Gramene" id="ABO95091">
        <property type="protein sequence ID" value="ABO95091"/>
        <property type="gene ID" value="OSTLU_30883"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30883"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_429870_0_0_1"/>
    <dbReference type="OMA" id="VFWGAKE"/>
    <dbReference type="OrthoDB" id="497540at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="637" mass="69713" checksum="ACF1C40FDED2D521" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVD1</accession>
    <name>A4RVD1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor Ts, mitochondrial</fullName>
            <shortName evidence="5">EF-Ts</shortName>
            <shortName evidence="5">EF-TsMt</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFTS</name>
        <name evidence="9" type="ORF">OSTLU_49408</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the EF-Ts family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417399.1">
        <property type="nucleotide sequence ID" value="XM_001417362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVD1"/>
    <dbReference type="STRING" id="436017.A4RVD1"/>
    <dbReference type="GeneID" id="5001420"/>
    <dbReference type="Gramene" id="ABO95692">
        <property type="protein sequence ID" value="ABO95692"/>
        <property type="gene ID" value="OSTLU_49408"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49408"/>
    <dbReference type="eggNOG" id="KOG1071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_623168_0_0_1"/>
    <dbReference type="OMA" id="IHAGSRI"/>
    <dbReference type="OrthoDB" id="277235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14275">
        <property type="entry name" value="UBA_EF-Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.20:FF:000001">
        <property type="entry name" value="Elongation factor Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000001">
        <property type="entry name" value="Elongation factor Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="entry name" value="Elongation factor Ts, dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="ELONGATION FACTOR TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741:SF10">
        <property type="entry name" value="POLYPROTEIN OF EF-TS, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="Elongation factor Ts (EF-Ts), dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EFTs/EF1B dimerisation" evidence="8">
        <location>
            <begin position="34"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Translation elongation factor EFTs/EF1B dimerisation" evidence="8">
        <location>
            <begin position="273"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="440" mass="48773" checksum="B49FAE9E6436BC0B" modified="2007-05-15" version="1">MMDCKKALQENNGDIAEATAWLRKKGMASADKKASRIAAEGAVVSYIHAGSRIGVLLELNCETDFVARGDRFKELAQDLAMQVAACPEVEYISPSDADQEMVARERDIEMQKEDLLSKPENIREKIVNGRIEKLVNEKALITKDFIKNTDVTVEDLVKTATAEIGEKISIRRFARFNLGEGIEKRVDDFAAEVAAQTQVKAAAPAAEPKEEKKEEKKEEDAPSVKVDAKLVKQLRDSTGCGMMDCKKALAQNNNSVEEATAWLRKKGMASADKKASRIAAEGAVVSYIHAGSRIGVLLELNCETDFVARGDRFKELAQDLAMQVAACPEVEYISPSDADQEMVARERDIEMQKEDLLSKPENIREKIVNGRIEKLVNEKALITKDFIKNTDVTVEDLVKTATAEIGEKISIRRFERFNLGEGIEKRNEDFAAEVAAQMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVF5</accession>
    <name>A4RVF5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417415.1">
        <property type="nucleotide sequence ID" value="XM_001417378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVF5"/>
    <dbReference type="GeneID" id="5001454"/>
    <dbReference type="Gramene" id="ABO95708">
        <property type="protein sequence ID" value="ABO95708"/>
        <property type="gene ID" value="OSTLU_30956"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30956"/>
    <dbReference type="HOGENOM" id="CLU_2965111_0_0_1"/>
    <dbReference type="OMA" id="KMASYDW"/>
    <dbReference type="OrthoDB" id="511048at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="59" mass="6387" checksum="C4D4ECCC3CD8A1F0" modified="2007-05-15" version="1">MRKMASYDWLSSGTGAVLCAGFFHWRGQSVGTALGVACVATIASVVIEELLEDRDQPWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVI9</accession>
    <name>A4RVI9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF819 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_37056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417428.1">
        <property type="nucleotide sequence ID" value="XM_001417391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVI9"/>
    <dbReference type="STRING" id="436017.A4RVI9"/>
    <dbReference type="GeneID" id="5001373"/>
    <dbReference type="Gramene" id="ABO95721">
        <property type="protein sequence ID" value="ABO95721"/>
        <property type="gene ID" value="OSTLU_37056"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37056"/>
    <dbReference type="eggNOG" id="ENOG502QQM4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034724_0_1_1"/>
    <dbReference type="OMA" id="MFWLVPF"/>
    <dbReference type="OrthoDB" id="498517at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008537">
        <property type="entry name" value="DUF819"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34289">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF819)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34289:SF3">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF819)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05684">
        <property type="entry name" value="DUF819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="42353" checksum="E2FD73976CEBF493" modified="2007-05-15" version="1">MSRDALASVARARAPAPARERRAKSRVRDGGASRTRRTRDAATRALIAPTDALGVWTAVLACGAFGLWAEKRPWGANAGGAPLVSTLAALALANAGIMPTDAPTYGMINGFLLPLAVPMLLFTADVRRVLRGSARLLPCFVVGALGTTLGTLGAFAAVPMTALGAEGWKMASALMARHIGGAVNFVAVANALEMTPNIMAAGLAADNLMNALYFMGLFALAKGVMPKTRDGGDGEGAGEPFSALRASYALAVAASVGYAAKLISAALNLRGMDIPIITLITVVLATAIPRRLGALAGSGEALATLVMQAFFVAVGASGSITHMLTTAPSLFVFSCLQVAIHLAFLLAVGKALRFDKANALLASNACVGGPTTAAAMASAKNWKSLVVPAMLVGVLGYTVATFLGIAFGKTVLARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVK2</accession>
    <name>A4RVK2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_36889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417432.1">
        <property type="nucleotide sequence ID" value="XM_001417395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVK2"/>
    <dbReference type="STRING" id="436017.A4RVK2"/>
    <dbReference type="GeneID" id="5001158"/>
    <dbReference type="Gramene" id="ABO95725">
        <property type="protein sequence ID" value="ABO95725"/>
        <property type="gene ID" value="OSTLU_36889"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36889"/>
    <dbReference type="eggNOG" id="KOG4626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1318387_0_0_1"/>
    <dbReference type="OrthoDB" id="546201at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052943">
        <property type="entry name" value="TMTC_O-mannosyl-trnsfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44809">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44809:SF1">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13431">
        <property type="entry name" value="TPR_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="209" mass="22850" checksum="7A6588D70A730B91" modified="2007-05-15" version="1" fragment="single">MHGLAICRAFAGDTEYAHAFAQRSASLTLTAQRQITLGNIFLAQGKLAKASTVYAMAIRRDPVSAVAHFNIGNAHFLAGDAASARVSYLAALDREPNYFKALYNLAIVIDSIGSVGEAKEWMKRAVDCRPNDSRATYALALLYVKLGQWKKAEYHFEQTLNLDAKHAPSQVKLGNLAFRRGDFQRSGANYLNALEVDPGNVEALTNLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVM4</accession>
    <name>A4RVM4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417443.1">
        <property type="nucleotide sequence ID" value="XM_001417406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVM4"/>
    <dbReference type="GeneID" id="5001387"/>
    <dbReference type="Gramene" id="ABO95736">
        <property type="protein sequence ID" value="ABO95736"/>
        <property type="gene ID" value="OSTLU_31028"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31028"/>
    <dbReference type="HOGENOM" id="CLU_1996458_0_0_1"/>
    <dbReference type="OrthoDB" id="10662441at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="125" mass="14174" checksum="D3DB3D9EAD14B2D9" modified="2007-05-15" version="1">MEPPRRAGKPQWNDSVDVDATPRKKTDKEYFDELHKLVEAKEAEEAKERLRQLQKKRRRRRAREAAAVKIRFEKSTIDSNLDPQSTISSKSITARAPRSSMDSTSSFQSAIEGACADVRDLALDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVM9</accession>
    <name>A4RVM9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_37212</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417444.1">
        <property type="nucleotide sequence ID" value="XM_001417407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVM9"/>
    <dbReference type="STRING" id="436017.A4RVM9"/>
    <dbReference type="GeneID" id="5001605"/>
    <dbReference type="Gramene" id="ABO95737">
        <property type="protein sequence ID" value="ABO95737"/>
        <property type="gene ID" value="OSTLU_37212"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37212"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1782286_0_0_1"/>
    <dbReference type="OMA" id="HIRVCEI"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="146" mass="16193" checksum="D1617EA5B2F29907" modified="2007-05-15" version="1" fragment="single">GYYDWVKEHIHEGAPINECDHCGDPPLVLAAGNGHTKVVELLLNEGADIQQSGLMKDTGLQRAAHNGHYHTVKFMLEQGADVDALDMGDNTALHWAAMRGHVEIVNLLLQNGADKNIKNKQECLPIDLCKAVWSNSYKYVREILAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW03</accession>
    <name>A4RW03_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_3993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417498.1">
        <property type="nucleotide sequence ID" value="XM_001417461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW03"/>
    <dbReference type="STRING" id="436017.A4RW03"/>
    <dbReference type="CAZy" id="GT77">
        <property type="family name" value="Glycosyltransferase Family 77"/>
    </dbReference>
    <dbReference type="GeneID" id="5001359"/>
    <dbReference type="KEGG" id="olu:OSTLU_3993"/>
    <dbReference type="eggNOG" id="ENOG502QRD4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064181_0_0_1"/>
    <dbReference type="OMA" id="PDKFARM"/>
    <dbReference type="OrthoDB" id="498615at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080147">
        <property type="term" value="P:root hair cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044290">
        <property type="entry name" value="RRA1/2/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46581">
        <property type="entry name" value="ARABINOSYLTRANSFERASE RRA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46581:SF3">
        <property type="entry name" value="ARABINOSYLTRANSFERASE RRA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="31608" checksum="1DCFDC3502BEA483" modified="2007-05-15" version="1" fragment="single">LCEVVRKVARNREVLAAVSNKNIFHMLELYIDGLKRTGITNYVIVALDSETADWCKQREVPYYHRELTSITGSTDNHATSGLKFRVLNEFVSTGTSVLLSDVDVVWMQDPFAAGESARNKRLIYRDADVEGMTDGWDDPTSYGFSWNGQRRLIARNSGLFFVAATHETKAMMSRLAERMASEKNTWDQTAYNEEQVYLWGQSKHKKYSGTSQRVMNYMCFQNSKYMFRFMRYDEDLYPDHRPASVHINYHPEKPDRMVSVIAQYWKGEANAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW06</accession>
    <name>A4RW06_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417242.1">
        <property type="nucleotide sequence ID" value="XM_001417205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW06"/>
    <dbReference type="STRING" id="436017.A4RW06"/>
    <dbReference type="GeneID" id="5001360"/>
    <dbReference type="Gramene" id="ABO95535">
        <property type="protein sequence ID" value="ABO95535"/>
        <property type="gene ID" value="OSTLU_31170"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31170"/>
    <dbReference type="eggNOG" id="ENOG502QRUJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1629821_0_0_1"/>
    <dbReference type="OMA" id="LYVKREM"/>
    <dbReference type="OrthoDB" id="2018626at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="163" mass="18432" checksum="4BEE54DF60098A28" modified="2007-05-15" version="1">MVTEIKDWLKLLYVKREMSFNEIKLTVGIEDPRLAENRERYGIEDESGVSADEKVETLEMIERGETPTDARAVSTLLEEFRNWPGLDAVVDQSVDAGPSRYEEIAMRSAGIKTSNPRRVRAKEAEEEKKEGTIFGFLPLYLVSAVPIFITVFAVGIMFVNSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW55</accession>
    <name>A4RW55_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">M23ase beta-sheet core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417265.1">
        <property type="nucleotide sequence ID" value="XM_001417228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW55"/>
    <dbReference type="STRING" id="436017.A4RW55"/>
    <dbReference type="MEROPS" id="M23.012"/>
    <dbReference type="GeneID" id="5001335"/>
    <dbReference type="Gramene" id="ABO95558">
        <property type="protein sequence ID" value="ABO95558"/>
        <property type="gene ID" value="OSTLU_31218"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31218"/>
    <dbReference type="eggNOG" id="ENOG502S3BI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1328296_0_0_1"/>
    <dbReference type="OrthoDB" id="204026at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12797">
        <property type="entry name" value="M23_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="entry name" value="Glucose Permease (Domain IIA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050570">
        <property type="entry name" value="Cell_wall_metabolism_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="M23ase_b-sheet_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21666:SF270">
        <property type="entry name" value="MUREIN HYDROLASE ACTIVATOR ENVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21666">
        <property type="entry name" value="PEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="Duplicated hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M23ase beta-sheet core" evidence="1">
        <location>
            <begin position="122"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="22405" checksum="37B52C0B2365D4C7" modified="2007-05-15" version="1">MHPKPNDTHSQSVGFPLRGERFLCTQNEGGELTHFFSGNLHAVDFRCPEGTPVLAVGDGEVIEVCDENTLTGIAVSNLFKWNSIVLKLDARSTPETPLRNASAECATTTEADVSTYDVRGGDLFVEYVHIRAKSAKVKVGDRVQRGQVICESGSVGFSPEPHLHFTAFRSGDDTADTVRVLFEACDTGATYLPRAGSYYTDSVGKCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWW4</accession>
    <name>A4RWW4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_15262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417647.1">
        <property type="nucleotide sequence ID" value="XM_001417610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWW4"/>
    <dbReference type="STRING" id="436017.A4RWW4"/>
    <dbReference type="GeneID" id="5002060"/>
    <dbReference type="Gramene" id="ABO95940">
        <property type="protein sequence ID" value="ABO95940"/>
        <property type="gene ID" value="OSTLU_15262"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15262"/>
    <dbReference type="eggNOG" id="KOG4441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_827398_0_0_1"/>
    <dbReference type="OMA" id="WVEKAMI"/>
    <dbReference type="OrthoDB" id="498042at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052392">
        <property type="entry name" value="Kelch-BTB_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46375:SF3">
        <property type="entry name" value="KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46375">
        <property type="entry name" value="KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="336" mass="36516" checksum="262482C7176A851B" modified="2007-05-15" version="1">MPNISGISGVSDLQAVTGNHGNVYLFGGIDTAGTVLDRVLEYDVIRQTYATKLPLDDARARFGAGALTSASTGLVDRIVVAGGVDSTQNAIKTAEYYDLSTGRSAAPGLSYDHMDGCMASTGDAVYMMGGWRAVGYDWFSVSKVEKLTRTGTAWETMADMPSPRGDCAAAGLKGKVYVAGGYDDATFNHTVGFKKNLYMYDPATNTWTEKAPMKHERGDLQLVALDDTLLAIGGEIKQARPDGSHANIVASHYVEEYFPEKDQWEERAYIGNARFRFGAAKSDWGTHVFGGSPVCLDPVNANVYTYCDGLQMSSHEVYFELSHPDVWVNYDAAHEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWX2</accession>
    <name>A4RWX2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417650.1">
        <property type="nucleotide sequence ID" value="XM_001417613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWX2"/>
    <dbReference type="GeneID" id="5002063"/>
    <dbReference type="Gramene" id="ABO95943">
        <property type="protein sequence ID" value="ABO95943"/>
        <property type="gene ID" value="OSTLU_31488"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31488"/>
    <dbReference type="HOGENOM" id="CLU_720392_0_0_1"/>
    <dbReference type="OrthoDB" id="10536689at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="384" mass="40571" checksum="2103A0B3A33DB904" modified="2007-05-15" version="1">MPLATSRAKKHDAIDDALTAEDAREHADKLAKSLSIFATIPRAIAEAHIRLRGRACPDERASDADVRGALLKALSDEVLAERECKLKGTKFEPYVNARPKPAAAAAAARTGRTTTRAVVDGDRRSASRETKIIGGDRGDGSDSDSSVGVASKFVPREIEDEDEDEDEDEDEDEDATTSDDEEEEYSSDGDYSGEDDYADDGGNFFGRAAEEPPAPEGANPFASMGDVDFGEEARAQIEEAKRIVAERKAQASNLADALASLQTSDPVSPTPSGRVAFSDKGDDVASIAGSIAGSDFTDRFDAISIASIAATLGSDATDRVADVDGSEFDVASLASHGTHRATTDLGSDDEREAAIFESEDERDSVSSDERHGAKENAPPSPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX54</accession>
    <name>A4RX54_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417697.1">
        <property type="nucleotide sequence ID" value="XM_001417660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX54"/>
    <dbReference type="STRING" id="436017.A4RX54"/>
    <dbReference type="GeneID" id="5002048"/>
    <dbReference type="Gramene" id="ABO95990">
        <property type="protein sequence ID" value="ABO95990"/>
        <property type="gene ID" value="OSTLU_31573"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31573"/>
    <dbReference type="eggNOG" id="KOG2177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1456762_0_0_1"/>
    <dbReference type="OrthoDB" id="533095at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="186" mass="19902" checksum="89DFD1B72D6D3A3B" modified="2007-05-15" version="1">MRATPRARARVATPRRRRRPRAVTPIASASSDARRATRRVALTTTAIALAAFGDARDARARPLAVVEARDAVARDGGRFTFEIELPRGYHFTEGANSRYETTAAASGTRGALEGDGGAKRTVVVRAAEGVNEARVDCVVYFCRTDDVCLMQRVRFEVPVATGGASETTAEYVVAAEANDAAVPSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX58</accession>
    <name>A4RX58_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417937.1">
        <property type="nucleotide sequence ID" value="XM_001417900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX58"/>
    <dbReference type="GeneID" id="5002051"/>
    <dbReference type="KEGG" id="olu:OSTLU_92717"/>
    <dbReference type="eggNOG" id="ENOG502S0ZX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_718429_0_0_1"/>
    <dbReference type="OMA" id="WAKVYST"/>
    <dbReference type="OrthoDB" id="496570at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="385" mass="42552" checksum="773FAF2B5AB4579F" modified="2007-05-15" version="1" fragment="single">LLYAPRCTCALRIAFIGDTGIGNDKPGSVWTDYLGNVRRPSYKVDGVECQTFDGKYCGAYSRAKNVFRLAADAGADLIVHAGDLDYASSPTSFFRFLTEHVWRRGISYIASKGNHDVDGWDGVSDLWSGPRGYQSLLRRQLPTLRGSTYSGSYGEDFIMETPDVLIVLSSVGAERPGESANRDHYDFLERALSSSKRKWKICVWHMTQERLQVSYKGDAVGFGAYEICRKYGAFIVTGHAHVYSRSFTMNRFGSKVYDFTREDLQVYDRETRRVLLRPSRASSNDGLTAVAVVGIGGYKNEAQLTDSGIWAKVYSTSCLASSPTCVRAPDASKFGALICDFDDASDRASCALRVVPYQGADDAAFRYRARAPDAVVDAFDLARVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX92</accession>
    <name>A4RX92_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">VIC family transporter: potassium ion channel subfamily H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_31611</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417956.1">
        <property type="nucleotide sequence ID" value="XM_001417919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX92"/>
    <dbReference type="GeneID" id="5001695"/>
    <dbReference type="Gramene" id="ABO96249">
        <property type="protein sequence ID" value="ABO96249"/>
        <property type="gene ID" value="OSTLU_31611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31611"/>
    <dbReference type="eggNOG" id="KOG0498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005746_2_1_1"/>
    <dbReference type="OMA" id="WLVTLGM"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050818">
        <property type="entry name" value="KCNH_animal-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217:SF435">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217">
        <property type="entry name" value="VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="13">
        <location>
            <begin position="12"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="472" mass="52881" checksum="EDE829F40F1518D1" modified="2007-05-15" version="1">MSVIEPFVIAFDYPMKLKGRGLSAAPIIDFVAGALFFIDTFVVNFLEAKVLTCRSTGRRKLITTPRLIRKIYILEGSFVTDVIVSVPFVVQIIASIKGESTPVERLTRILRLLRVLRVTGSSLTTPEILFMKLFRMTPMVIFIAQTLLVFALLVHSVACVYIFVAIQEGRNQSWLTQADLADGSNSEIYIVALYFATATITTVGFGDISAGSNDLERCISTVAMIVGAIFFAYLVGSMGASIQALSTTMSRQRKFRERVTRVHAFLDRQHAPTHIRRHIMSFISEVEPRRTFLRENEEIMKSLPTDLMASMAHHMLAPNVGRIFGNVSNGLCQHIVSVFELVVIEPGMVIDSGYFYVVTEGVVAISSPNERKMIAVLTGQADAYLCYFGLDELIPPERRKSVRASALTVCELWRARASAIEEIFKSHPFLAQIMLEKIRSLEDDEFSELLAYRVFILESFLARFVAMRESGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXD3</accession>
    <name>A4RXD3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytosol aminopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_2836</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer (dimer of homotrimers).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417730.1">
        <property type="nucleotide sequence ID" value="XM_001417693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXD3"/>
    <dbReference type="STRING" id="436017.A4RXD3"/>
    <dbReference type="MEROPS" id="M17.A01"/>
    <dbReference type="GeneID" id="5001913"/>
    <dbReference type="KEGG" id="olu:OSTLU_2836"/>
    <dbReference type="eggNOG" id="KOG2597">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013734_5_1_1"/>
    <dbReference type="OMA" id="VDAMDYP"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002076">
        <property type="entry name" value="PRK00913.2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="6">
        <location>
            <begin position="301"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="445" mass="45550" checksum="AF21F5A7139DB65E" modified="2007-05-15" version="1" fragment="single">LRAFDAASGGAVRAMIEEGEFKGKVGTSAFSRAIAGTAKHVGVVGVGKRGEATTSAMLTLGSAAAAQAQKSKCKTLGIKGADGFENAVAAGAYLGATEDQRFKSKPQAKTLESVSLLDVSADVSEGKARAVGVQLTKDLVAAPPNVVTPTAMAEVAKSIAAAHPDCMSVKILEKADCEKLGMGSFLGVSEASDEPPKFIHLTYKGAGSDLKKVAVVGKGLTFDSGGYNLKAGAGSMIEMMKFDMGGSGATLGAAKIIAQTKPAGVECHFIIASCENMIGSRGLRPGDILTASNGKTIEVNNTDAEGRLTLADALVYADKTCGATAIVDCATLTGAIIVALGNDIAGLFSPKDAAAKRVEDAAKAAGEDLWRMPMPDSMWSIMKSEIADMKNTGSRGGGSITAALFLKQFVDESVEWSHVDLAGPVWDDKKGGATGYGAALFAAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXN7</accession>
    <name>A4RXN7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417789.1">
        <property type="nucleotide sequence ID" value="XM_001417752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXN7"/>
    <dbReference type="GeneID" id="5002102"/>
    <dbReference type="Gramene" id="ABO96082">
        <property type="protein sequence ID" value="ABO96082"/>
        <property type="gene ID" value="OSTLU_31759"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31759"/>
    <dbReference type="eggNOG" id="KOG2942">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_795340_0_0_1"/>
    <dbReference type="OMA" id="EYSHAWV"/>
    <dbReference type="OrthoDB" id="4882at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818:SF0">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="286" mass="31527" checksum="D89B2F84021BAABD" modified="2007-05-15" version="1">MFAPIARARSAFSRRNGTPRQGGALVPRARCEVKMEARLPRHLLEGLDEYTHCWVIYVFHANTNLAGTKTGGAAKGKVAVPRLDGKRVGALATRTPHRPIPVGLSVGTVESVDAERGVVVIGGIDLVDGTPILDIKPYVPFCDSIASAKAPDWVGKEAVGKDEPLKIIRVDVAERAEAPLASSYARSAAAKTLYPDVSAFVEFCKEVLTYDIRSIRERNADVDKRKFDTYRVILCDVEIEYTISEERKVEITGAKAVPREIFDDWERAKVEQQAREALGEHPKPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXV3</accession>
    <name>A4RXV3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Membrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_38773</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GOSR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418061.1">
        <property type="nucleotide sequence ID" value="XM_001418024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXV3"/>
    <dbReference type="STRING" id="436017.A4RXV3"/>
    <dbReference type="GeneID" id="5002145"/>
    <dbReference type="Gramene" id="ABO96354">
        <property type="protein sequence ID" value="ABO96354"/>
        <property type="gene ID" value="OSTLU_38773"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38773"/>
    <dbReference type="eggNOG" id="KOG3251">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083740_1_1_1"/>
    <dbReference type="OMA" id="LKYDSRH"/>
    <dbReference type="OrthoDB" id="158360at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027027">
        <property type="entry name" value="GOSR2/Membrin/Bos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF1">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028865">
        <property type="entry name" value="Membrin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="224" mass="25804" checksum="7F14DCDAF192DEC3" modified="2007-05-15" version="1">MASLEDLYAVSRRLCFDVTEGLSKLERDEGRGHGVNDGLAREMRTRMGELKKITSEMERQWRAMAMTASIAKSDTWKRKVEHVIEETDHLEMSLHRFGSREERRLNEQKEREDLMRRVTDDEGFRSLVGEYDAESGSMKSVRRSGSMVDELLEQGASVLGNLSEQSATLRNVKRKVFSLLDKMGVSSSLLRVIDRRQRLDAILVYGGMFATVLILFIVWMFFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXY9</accession>
    <name>A4RXY9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-ATPase family transporter: protons (Vacuolar)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_9572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418079.1">
        <property type="nucleotide sequence ID" value="XM_001418042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXY9"/>
    <dbReference type="STRING" id="436017.A4RXY9"/>
    <dbReference type="GeneID" id="5001992"/>
    <dbReference type="Gramene" id="ABO96372">
        <property type="protein sequence ID" value="ABO96372"/>
        <property type="gene ID" value="OSTLU_9572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9572"/>
    <dbReference type="eggNOG" id="KOG2759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2257018_0_0_1"/>
    <dbReference type="OMA" id="MALIDHE"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="104" mass="11622" checksum="5ED15E9421A0D3D9" modified="2007-05-15" version="1" fragment="single">RDEVMSGSLEWSAAHKDEGFWRECATKLTDNNCQILRVLIKLIDGSEAMDPKTLAVACNDIGEFAVHYPAGRFLANDLGGKEHSMRLMSHEDDEVRKSALQCVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYQ7</accession>
    <name>A4RYQ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_32113</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418435.1">
        <property type="nucleotide sequence ID" value="XM_001418398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYQ7"/>
    <dbReference type="STRING" id="436017.A4RYQ7"/>
    <dbReference type="GeneID" id="5002227"/>
    <dbReference type="Gramene" id="ABO96728">
        <property type="protein sequence ID" value="ABO96728"/>
        <property type="gene ID" value="OSTLU_32113"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32113"/>
    <dbReference type="eggNOG" id="KOG2145">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032621_0_1_1"/>
    <dbReference type="OMA" id="SIYHRFM"/>
    <dbReference type="OrthoDB" id="10261385at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000007">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000033">
        <property type="entry name" value="tryptophan--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055">
        <property type="entry name" value="TRYPTOPHANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="425"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="461"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO96728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="484" mass="53884" checksum="D0A4766A040EA25A" modified="2007-05-15" version="1">MTDVEDDARETTATEQVVTPWDVEGKDGGGIDYDKLVRDFGCSTIDREMIERVERVTGRKAHPFLRRGMFFAHRELDLILDAYERGEKFYLYTGRGPSSESLHLGHLIPFQFTKWLQDAFKVPLVIQLTDDEKFLWKDLSLEECGRLARENAKDIIACGFDPKRTFIFSDVQYMSTPFYKNMMKIAKCVTLNQVKGIFGFTGESNIGQVGFPPTQAAPSFPDCFPHMFGESKTSLRCLIPCAIDQDPYFRMTRDVAPRIGGYKPALIESRFFPALKGESGKMSASDATSAIYVTDTPKEIKTKVNKYAFSGGQLTVEDHRRLGGNLDTDISWKWLNFFLDDDQALAEIGEEYSSGRMLSGEIKAKLIETLVPICQGHQDARAKVTDAMIDEFMSTKPRVFASLFGDMGDVAGALDEATIANTKPGIAIGAPEDTGSVKKEQDKAQTGEDGGQMSKSQQKKLLKEQQIAEKKRAKEAAKAAGQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZF4</accession>
    <name>A4RZF4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418320.1">
        <property type="nucleotide sequence ID" value="XM_001418283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZF4"/>
    <dbReference type="GeneID" id="5002457"/>
    <dbReference type="Gramene" id="ABO96613">
        <property type="protein sequence ID" value="ABO96613"/>
        <property type="gene ID" value="OSTLU_32366"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32366"/>
    <dbReference type="HOGENOM" id="CLU_407930_0_0_1"/>
    <dbReference type="OMA" id="FIGWSEY"/>
    <dbReference type="OrthoDB" id="10465864at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="674" mass="70801" checksum="96BEEC7A4AA9BA5E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZJ2</accession>
    <name>A4RZJ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GPI-anchored wall transfer protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_15960</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418580.1">
        <property type="nucleotide sequence ID" value="XM_001418543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZJ2"/>
    <dbReference type="STRING" id="436017.A4RZJ2"/>
    <dbReference type="GeneID" id="5002742"/>
    <dbReference type="Gramene" id="ABO96873">
        <property type="protein sequence ID" value="ABO96873"/>
        <property type="gene ID" value="OSTLU_15960"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15960"/>
    <dbReference type="eggNOG" id="KOG0411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020802_0_0_1"/>
    <dbReference type="OMA" id="DLCFAME"/>
    <dbReference type="OrthoDB" id="15270at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032216">
        <property type="term" value="F:glucosaminyl-phosphatidylinositol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009447">
        <property type="entry name" value="PIGW/GWT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06423">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="35775" checksum="7BE32E9BCD310835" modified="2007-05-15" version="1">MTVVAILAVDFTLFPRRLGKTETYGVSLMDVGAGSFVFSSSVVSRFARGKEKRNLRASRRKVMQVMLLGLARLAITTMIGYHSVETEYGRHWNFFFTLAVIQVCADTLPIAAHRALPFGLLISFAYQYVLSCHGLSAWILQAPDVRSHESETNVLTRFVSMNREGVSSACGGYFAIHLIAAHLGNALSKPVLNFSRWLQTMAIVTCAFWFAAIASHAYVEPTSRRAGNAAYVLWIVAFNLQVIIVYVCMTWFARSANGRGKCDIPVLASAINRRQLFVFVVGNALTGLTNLAVDTINADANTAWGVMSLYLSAISIVALAMDRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1B5</accession>
    <name>A4S1B5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-guanine(15) transglycosylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_42734</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419335.1">
        <property type="nucleotide sequence ID" value="XM_001419298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1B5"/>
    <dbReference type="STRING" id="436017.A4S1B5"/>
    <dbReference type="GeneID" id="5003081"/>
    <dbReference type="Gramene" id="ABO97628">
        <property type="protein sequence ID" value="ABO97628"/>
        <property type="gene ID" value="OSTLU_42734"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42734"/>
    <dbReference type="eggNOG" id="KOG3908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022060_0_2_1"/>
    <dbReference type="OMA" id="RRDFYPI"/>
    <dbReference type="OrthoDB" id="10249838at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43468">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43468:SF1">
        <property type="entry name" value="TRNA-GUANOSINE(34) QUEUINE TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="6">
        <location>
            <begin position="67"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="437" mass="48177" checksum="81E15D9E21CCEF29" modified="2007-05-15" version="1">MRVARVARARGVLDRVARASRCARARDASASARSSASTDARLERAPAASPASPRFRFEVLRASTRSNARAGMIHTPRGTIATPGYVAVGTNAAMKAVRGDALRRAGIDLMFANTYHLMLQPGAATVEAMGGIHAFMGRRGPVITDSGGFQVFSLGTPDRSANAKGKTKELKSRKATKHRRENLLIDVSEEGATFRSYRDGTKMTLTPESSVLSQKQIGADIIIPLDELPPYDIDRETLEESVHRSHRWMTRSLETHLKDVRQQAMYGVVHGGVDRELRRMSVEYLSALPFDGLAIGGSLGRDAAELGALLEFLMPLLPKHLPNHLLGIADMENIEHAVANGVDTFDSCYPTQVARHGTLFTRSRGRINFRRAEFRTSTEPACEECECTLCTKHTLGYLHHLDRANEPLAWSLASEHNLYHMGDKMRRVREGILNGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1C6</accession>
    <name>A4S1C6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD synthase</fullName>
            <ecNumber evidence="2">2.7.7.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_5377</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419126.1">
        <property type="nucleotide sequence ID" value="XM_001419089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1C6"/>
    <dbReference type="STRING" id="436017.A4S1C6"/>
    <dbReference type="GeneID" id="5003088"/>
    <dbReference type="Gramene" id="ABO97419">
        <property type="protein sequence ID" value="ABO97419"/>
        <property type="gene ID" value="OSTLU_5377"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5377"/>
    <dbReference type="eggNOG" id="ENOG502QVVU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057424_1_0_1"/>
    <dbReference type="OMA" id="WETRLPI"/>
    <dbReference type="OrthoDB" id="414641at2759"/>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAD synthetase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="175" mass="18572" checksum="B7AC6D9766504A02" modified="2007-05-15" version="1" fragment="single">VCLGKFDAMHRGHLALAERAATRGDVVVVSFSGMAETLGWETRLPITAPSDRSRVLAMWSGTTGAAVSEHALAFGDVRELSPEAFVEMLARMGVGAVVTGKNYRFGYKAAGDVEALKRFGEANGLTVDVVDLVPARRPSSAGLGDQVSSSRIRSALSAGDIDEVNEMLGREHRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1E6</accession>
    <name>A4S1E6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419352.1">
        <property type="nucleotide sequence ID" value="XM_001419315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1E6"/>
    <dbReference type="STRING" id="436017.A4S1E6"/>
    <dbReference type="GeneID" id="5003098"/>
    <dbReference type="Gramene" id="ABO97645">
        <property type="protein sequence ID" value="ABO97645"/>
        <property type="gene ID" value="OSTLU_33072"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33072"/>
    <dbReference type="eggNOG" id="ENOG502QS91">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_491228_0_0_1"/>
    <dbReference type="OMA" id="GGRKCFT"/>
    <dbReference type="OrthoDB" id="551300at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009704">
        <property type="term" value="P:de-etiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090333">
        <property type="term" value="P:regulation of stomatal closure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044690">
        <property type="entry name" value="CAS_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34209:SF1">
        <property type="entry name" value="CALCIUM SENSING RECEPTOR, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34209">
        <property type="entry name" value="RHODANESE/CELL CYCLE CONTROL PHOSPHATASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="56854" checksum="8064987D2CEE4A6E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1N2</accession>
    <name>A4S1N2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ZIP family transporter: zinc ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_42358</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419395.1">
        <property type="nucleotide sequence ID" value="XM_001419358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1N2"/>
    <dbReference type="STRING" id="436017.A4S1N2"/>
    <dbReference type="GeneID" id="5003233"/>
    <dbReference type="Gramene" id="ABO97688">
        <property type="protein sequence ID" value="ABO97688"/>
        <property type="gene ID" value="OSTLU_42358"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42358"/>
    <dbReference type="eggNOG" id="KOG2474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015114_1_3_1"/>
    <dbReference type="OMA" id="FRMAFIT"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003243">
        <property type="entry name" value="PRK04201.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF205">
        <property type="entry name" value="ZINC TRANSPORTER ZUPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="269" mass="28383" checksum="7CF269EFE3916902" modified="2007-05-15" version="1" fragment="single">DVGLAFGLVIMAGLSTAIGSAFVFCSARADTGVLARALGASAGVMIYVSFAEIYCVKSVEAFTEVCGSDGNCGWRYASLCFFGGLIFMYGLDFVVHKANDGGNVDLTDVHHKAIEAKTLKNMGVMTAIAIGLHNFPEGLATFVAALADPKLGAALAIAIAIHNVPEGICVAMPIYYATGSKWKGFWWSFLSGLSEPVGAIFGYAILNGNDMSPAAFGSLFGLVAGMMVFISVKELIPTALKYDPHDEYVTTYVFVGMAIMAASLILFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1R3</accession>
    <name>A4S1R3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">15-cis-phytoene synthase</fullName>
            <ecNumber evidence="2">2.5.1.32</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_5923</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34475"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.32"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="2"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419412.1">
        <property type="nucleotide sequence ID" value="XM_001419375.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1R3"/>
    <dbReference type="STRING" id="436017.A4S1R3"/>
    <dbReference type="GeneID" id="5003107"/>
    <dbReference type="Gramene" id="ABO97705">
        <property type="protein sequence ID" value="ABO97705"/>
        <property type="gene ID" value="OSTLU_5923"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5923"/>
    <dbReference type="eggNOG" id="KOG4411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037269_6_0_1"/>
    <dbReference type="OMA" id="MINAREQ"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046905">
        <property type="term" value="F:15-cis-phytoene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480">
        <property type="entry name" value="BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="293" mass="31170" checksum="F4369D8D75BDE870" modified="2007-05-15" version="1" fragment="single">STSASTDDLRAAFRHCVEIVRARDYETYLCTLALPRASAPAAFAVRALNAETGSVVGNAESVDAAVARLMWWRETMTAGSAGTRAGHPVALATLAALGNEPNARARTWMRRMIEARIADARSDGPPRTIADLERYASDAHGSALTLALDACGVRNADADHAVSHLGQAIGLSALLRGTVAHAKQRRCYLPSDACARHGVSTESVYRMEPSEGVRNVAHEVASAAKGHLDSARAMASRVPDDAKPFLLQAVPVGRYLDALEARDFDVFDEAVAKGGAPLLTQGAIAWHAFKRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Y0</accession>
    <name>A4S1Y0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419227.1">
        <property type="nucleotide sequence ID" value="XM_001419190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Y0"/>
    <dbReference type="STRING" id="436017.A4S1Y0"/>
    <dbReference type="GeneID" id="5003142"/>
    <dbReference type="Gramene" id="ABO97520">
        <property type="protein sequence ID" value="ABO97520"/>
        <property type="gene ID" value="OSTLU_33258"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33258"/>
    <dbReference type="HOGENOM" id="CLU_2337413_0_0_1"/>
    <dbReference type="OrthoDB" id="88410at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34724">
        <property type="entry name" value="OS12G0596101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34724:SF2">
        <property type="entry name" value="OS12G0596101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="98" mass="10878" checksum="72EB8C5505EFA602" modified="2007-05-15" version="1">MCRRVQCSKCDKPTWAGCGMHIESALAGVAVEDRCACERGSVFGSLFGGKKTSNKEEVDARLSSPASERRKKGERIMITITVYATSRARIRIRRRARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S209</accession>
    <name>A4S209_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EngB-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_33284</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419457.1">
        <property type="nucleotide sequence ID" value="XM_001419420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S209"/>
    <dbReference type="STRING" id="436017.A4S209"/>
    <dbReference type="GeneID" id="5003320"/>
    <dbReference type="Gramene" id="ABO97750">
        <property type="protein sequence ID" value="ABO97750"/>
        <property type="gene ID" value="OSTLU_33284"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33284"/>
    <dbReference type="eggNOG" id="KOG2486">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_661209_0_0_1"/>
    <dbReference type="OMA" id="FYGGEWK"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
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        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47560:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
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        <property type="entry name" value="G_ENGB"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EngB-type G" evidence="8">
        <location>
            <begin position="105"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="280"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="282"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="379"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="416" mass="44860" checksum="4FA588E80D942602" modified="2007-05-15" version="1">MSNRAKFRALPIDHGIMGRIKKYSLSTNASTAGRTTRVLRNRNEISEVTQRYAMYDVGMLEVKTQRLLGFGRSKRTAKFIAAAAREGEEPPKHAVGKGASKIKDDVPEIAFAGRSNVGKSSLINALTLSSVARSSDVPGKTQSLNFYSMDERIRLVDLPGYGFAFAKQHRVESWNELMDKYLTSRPNLKRVYLVIDARHGMKASDREMLAFLSKYGETQCGVILNKCDYVNPNELARRAYLIQEELRYTKRARTMVLMASTSTGAGVTEIAREIYGMALDDPSGEEYDDDDDVESESDGEYGEGDVGDDDSFAGSSSKKTEFYGGEWKPGQKASKKYTPASKAVPAAGRGGRGGRGGRGAQGGRGGPSGRGGRGRGGRGRGDDARGDEARGGGRSGGRSGGRGRGKGFTQGTPGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S269</accession>
    <name>A4S269_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_34891</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ABO97990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4S269"/>
    <dbReference type="GeneID" id="5003904"/>
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        <property type="gene ID" value="OSTLU_34891"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028567_26_0_1"/>
    <dbReference type="OMA" id="RWHASIK"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
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    </dbReference>
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        <property type="entry name" value="Homeodomain-like"/>
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    </dbReference>
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        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
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        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF25">
        <property type="entry name" value="MYB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="14"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="19"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="67"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="67"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="119"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="123"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="180" mass="20771" checksum="E0A0802FD0EE83DF" modified="2007-05-15" version="1" fragment="single">RRARVASRKIGGPTRRSAKGGWTPEEDELLRGAVAVYGGRNWKKIAVYFSDSRTDVQCLHRWQKVLNPELVKGPWTAEEDARIIELVTELGAKRWSKIAGELPGRIGKQCRERWYNHLDPEIKREEWSADEDRQLIIAHAQYGNRWAEIAKSFKGRTDNAIKNHWNSTLKRKVDQALNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Q6</accession>
    <name>A4S2Q6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_33532</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419791.1">
        <property type="nucleotide sequence ID" value="XM_001419754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Q6"/>
    <dbReference type="STRING" id="436017.A4S2Q6"/>
    <dbReference type="GeneID" id="5003572"/>
    <dbReference type="Gramene" id="ABO98084">
        <property type="protein sequence ID" value="ABO98084"/>
        <property type="gene ID" value="OSTLU_33532"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33532"/>
    <dbReference type="eggNOG" id="KOG3071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048483_0_1_1"/>
    <dbReference type="OMA" id="WTYFTST"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="298" mass="34120" checksum="B90154077BB3C1F1" modified="2007-05-15" version="1">MAQFPLVSLCAFAVYGYATYAYAFEWSHARTPGGLANVDAQRWIGDLSFALPACATTAYLMFCLVGPRVMAKREAFDPKGLMLAYNAYQTAFNVCVLGMFIREIVTLKQPTWGSKMPWSDKRSFNILLGVWFHYNNKYLELLDTAFMIARKKTNQLSFLHVYHHALLIWAWWFVCHLMATNDCVDAYFGAACNSFIHIVMYSYYLMAALGVRCPWKRYITQAQMLQFVIVFVHAVFVLREKHCPVSLPWAQMFVMANMLVLFGNFYLKAYAAKPSGKSSTRVSAAKPATRRTRSRKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2W3</accession>
    <name>A4S2W3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419606.1">
        <property type="nucleotide sequence ID" value="XM_001419569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2W3"/>
    <dbReference type="GeneID" id="5003767"/>
    <dbReference type="Gramene" id="ABO97899">
        <property type="protein sequence ID" value="ABO97899"/>
        <property type="gene ID" value="OSTLU_25066"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25066"/>
    <dbReference type="HOGENOM" id="CLU_770284_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="360" mass="40642" checksum="74F70ED193774ACA" modified="2007-05-15" version="1">MTSRGLPMDVSLRFLSDEDDGQRGGGGKPYARRGGKKASGSANGKGSGGSRGTTSEANVKRSEKYGAPKPRKPRTLRLDVDEDRVEEYCVALREHQELTRVYDYHAKIVDKCDESQLLAFMARVLKSVIDNIVEENTAHGQYLAKATLRCDVGALHILDAFCVTLYKKAEEYNKYSPDLLLLESVMSDSRQDPDAAVDMNLLAIEFGFNARLCDCLNKVIEETAEKKGLTEADKKRLQRRWRLWLKNKSFDDCRPNPFNHAQLSTYVEPPYTINYQLHTNESAVFAVLTSDQINPFAMQCKTLGEAPKNAPEEIEIYDSKTKKGKTFQEIVDILQKIVKSPRATQGAQKAKDENIFRYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4S352</accession>
    <name>A4S352_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419653.1">
        <property type="nucleotide sequence ID" value="XM_001419616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S352"/>
    <dbReference type="GeneID" id="5003523"/>
    <dbReference type="Gramene" id="ABO97946">
        <property type="protein sequence ID" value="ABO97946"/>
        <property type="gene ID" value="OSTLU_16909"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16909"/>
    <dbReference type="HOGENOM" id="CLU_1269774_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23748" checksum="89C142CEF77DE4EE" modified="2007-05-15" version="1" fragment="single">MEDLHAIGDVVRELCAVDDGVLMRSTLGCMDGFKVALRAEREDDDEARREICVAALFGLSKLATTAREQVIGGDVEEDVVLEMLRVQCKAPNMRFSERARAMSTYVKAVGVRENLTNVNVRTPPASPKDKSGRTIGGLARAFASQQEMADFNTPDVSDDEGTEERRQSMSSLCASPSRIFYSPKILSGDGTVVDEAITPPGTVICRICEQPVAKRTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S394</accession>
    <name>A4S394_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_37953</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420057.1">
        <property type="nucleotide sequence ID" value="XM_001420020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S394"/>
    <dbReference type="STRING" id="436017.A4S394"/>
    <dbReference type="GeneID" id="5004117"/>
    <dbReference type="Gramene" id="ABO98350">
        <property type="protein sequence ID" value="ABO98350"/>
        <property type="gene ID" value="OSTLU_37953"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37953"/>
    <dbReference type="eggNOG" id="KOG2007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013528_0_1_1"/>
    <dbReference type="OMA" id="IMRWPSP"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000009">
        <property type="entry name" value="Cysteine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF25">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="12">
        <location>
            <begin position="15"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO98350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="497" mass="55265" checksum="C3FC1B75DD184719" modified="2007-05-15" version="1">MTRKKEIFTPRDPAGKKVQMYVCGVTVYDYSHIGHARVYVAFDVLYRQLMRLGYDVTYCRNFTDIDDKIIKRSNESGETCEALTDKFIEAFHEDMAALGCLRPTLEPRATECVDDIIAFIERLIAKGNAYETEGDVYFSVDTLPAYGALSGRNQEDNRAGERVAVDGRKKNPADFALWKTAKPGEPTWTSPWGEGRPGWHIECSAMIEKMLGPTIDIHGGGQDLVFPHHENELAQSSAACGCGAHADENPFVRYWVHNGFVKVDSEKMSKSLGNFFTIREVLDKYHPFVLRFMLLGAHYRAPINYTQRALEEASDRVYYLYQTVHDVRAILRDAAAEEPAKKPVPLVADALKLASEAEKQVSEALNDDMNTPGVIATLSAPLKSMNDFMTTKAGKKAVGRVGALQSLLSTVEGLMEAVGMPKDEENVILAELRARALHRAGLTEDDLLAKIEERNKARDAKDFAESDRLRDELSARGVGLMDGSAVPWRPVPVIDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3C4</accession>
    <name>A4S3C4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419895.1">
        <property type="nucleotide sequence ID" value="XM_001419858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3C4"/>
    <dbReference type="STRING" id="436017.A4S3C4"/>
    <dbReference type="GeneID" id="5004130"/>
    <dbReference type="Gramene" id="ABO98188">
        <property type="protein sequence ID" value="ABO98188"/>
        <property type="gene ID" value="OSTLU_26006"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26006"/>
    <dbReference type="eggNOG" id="KOG2724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_904283_0_0_1"/>
    <dbReference type="OMA" id="SWVQMQL"/>
    <dbReference type="OrthoDB" id="551031at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="160"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="32911" checksum="B01AF406DC11B5AB" modified="2007-05-15" version="1">MGKRAAPDATTGDAESRRVEREAKCRGTVEALNAQFAAWIARRAIESPIVSWRRGCEDYLKHLDRVKVDFGDVLERVEDENDGETTKATTTASDGRVDAKGSVNPFGGGAVAAVPAAGSIFGSLPTAPGSTFGAPFGGGGGLFGGGTAPGAGTAADDEDEDEPARPSSPSYQANEAVEDEKEVVLLRVGKVKFHTKKDAGDKNWADRGVNSFEFRREKAPSEGDVKRCRLLMRNTIGKAVLNAGLYPKMSSQLTEKKMKDGSAVQNGLIATVFNAEEENQKVMVYLRFGKESDAKELHKLISENVATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3C5</accession>
    <name>A4S3C5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CP12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420070.1">
        <property type="nucleotide sequence ID" value="XM_001420033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3C5"/>
    <dbReference type="GeneID" id="5004210"/>
    <dbReference type="Gramene" id="ABO98363">
        <property type="protein sequence ID" value="ABO98363"/>
        <property type="gene ID" value="OSTLU_16972"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16972"/>
    <dbReference type="HOGENOM" id="CLU_1535042_0_0_1"/>
    <dbReference type="OrthoDB" id="498518at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02672">
        <property type="entry name" value="CP12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="18499" checksum="DE5A529DBCC2DCCF" modified="2007-05-15" version="1">MILREAVERAKASCEEEGTASASCVTAWEEVAEVRDAASRAGVRTRGEGEDLDLNARGKTTKAEEAAKRAKAKEMRERLAKDPLMGSLPCRGLGECTVAEGTLEARGRLMAREEDGDAATSGEADPSAARRSAVEAAVARAIELCASGATREACAIAWEEVEELTSWGGGRREGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S436</accession>
    <name>A4S436_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420200.1">
        <property type="nucleotide sequence ID" value="XM_001420163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S436"/>
    <dbReference type="STRING" id="436017.A4S436"/>
    <dbReference type="GeneID" id="5003925"/>
    <dbReference type="Gramene" id="ABO98493">
        <property type="protein sequence ID" value="ABO98493"/>
        <property type="gene ID" value="OSTLU_26270"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26270"/>
    <dbReference type="HOGENOM" id="CLU_1306646_0_0_1"/>
    <dbReference type="OMA" id="WITNSER"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd17716">
        <property type="entry name" value="BRCT_microcephalin_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="211" mass="22976" checksum="4D4F54AE740B4BBC" modified="2007-05-15" version="1">MRPIFDGVSAYVDVTLTGNVDASAPFRAKLVAKGAKVTVNICPTTTHVIFRAADAARGVALHRKLAEMKLASKVKVVSPLWITNSERRGEMVDAKDFATTPRGVPSKYSTTPKRNVTPKNASRSGTKKRDRECLESVDLMKYDSDVRRMAEIAAELDAERARAAALDDGDATTKKTFAEAVRATSAKKKRRKVEFSECDENVAPTEDSNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4N3</accession>
    <name>A4S4N3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">30S ribosomal protein S9, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MRPS9</name>
        <name evidence="6" type="ORF">OSTLU_44376</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420298.1">
        <property type="nucleotide sequence ID" value="XM_001420261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4N3"/>
    <dbReference type="STRING" id="436017.A4S4N3"/>
    <dbReference type="GeneID" id="5004542"/>
    <dbReference type="Gramene" id="ABO98591">
        <property type="protein sequence ID" value="ABO98591"/>
        <property type="gene ID" value="OSTLU_44376"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44376"/>
    <dbReference type="eggNOG" id="KOG1697">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046483_2_0_1"/>
    <dbReference type="OMA" id="KFQFSKR"/>
    <dbReference type="OrthoDB" id="10254627at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_uS9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="137" mass="14899" checksum="72CAE3CC71936EDF" modified="2007-05-15" version="1">MVRVPIRDVAGRSYGTGKRKTAVARVWLAPGSGEHKVNGKPYDEYFSSPAARADMIAPFFVSDTLGLFTAVVDVRGGGISGQAQAVRHGVSVALQNYDPAFRPALKAAGYLKRDPRIVERKKPGKAKARKSFAWVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4V1</accession>
    <name>A4S4V1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420501.1">
        <property type="nucleotide sequence ID" value="XM_001420464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4V1"/>
    <dbReference type="GeneID" id="5004509"/>
    <dbReference type="Gramene" id="ABO98794">
        <property type="protein sequence ID" value="ABO98794"/>
        <property type="gene ID" value="OSTLU_26538"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26538"/>
    <dbReference type="HOGENOM" id="CLU_3090646_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="52" mass="5568" checksum="693D3AAFD2E81AEB" modified="2007-05-15" version="1">MSLAVAATLCTRDLRREHQRKQVSPSRAPSECSSADETASHALRSLNVSGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S572</accession>
    <name>A4S572_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420721.1">
        <property type="nucleotide sequence ID" value="XM_001420684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S572"/>
    <dbReference type="GeneID" id="5004788"/>
    <dbReference type="Gramene" id="ABO99014">
        <property type="protein sequence ID" value="ABO99014"/>
        <property type="gene ID" value="OSTLU_17471"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17471"/>
    <dbReference type="eggNOG" id="ENOG502SUF1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1051261_0_0_1"/>
    <dbReference type="OMA" id="GRDHAMH"/>
    <dbReference type="OrthoDB" id="416542at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29628" checksum="9EA722EB9E42C6E0" modified="2007-05-15" version="1">MCDRVRRARAKERASTTDADAQDDTRRGGASWTPTATTREGVPTRLRGAQAKGVSWCWATRANGSICGARADCENSCLPYCAEHLERGDEALRVVKHPVFGDKILIATRDLPKGYKTVYFGERKTWRECGRAGRDHAMHFRSGGGVIDPCPLGDAAQLQFMSNPGPNEVSNNRSTNVFFGDTRCPKRTLVGREFILSRDVKKGAQLLQWYGADWFNSRDIKRLDVGCDVYPAERKKRKQERADHPNREPSRAKVLGDATNASSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S573</accession>
    <name>A4S573_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iojap-like ribosome-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_17472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420559.1">
        <property type="nucleotide sequence ID" value="XM_001420522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S573"/>
    <dbReference type="STRING" id="436017.A4S573"/>
    <dbReference type="GeneID" id="5004740"/>
    <dbReference type="Gramene" id="ABO98852">
        <property type="protein sequence ID" value="ABO98852"/>
        <property type="gene ID" value="OSTLU_17472"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17472"/>
    <dbReference type="eggNOG" id="KOG3212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_827394_0_0_1"/>
    <dbReference type="OMA" id="INVRDQC"/>
    <dbReference type="OrthoDB" id="536794at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="IOJAP SUPERFAMILY ORTHOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043:SF0">
        <property type="entry name" value="MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02410">
        <property type="entry name" value="RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36744" checksum="64DE3BDE56D97A79" modified="2007-05-15" version="1">MAERMSVLRASGELGRRETLSVVSTSSSGFGNMGGTNVRTMTPGLIEFEQFLVESGWRVDSERKAISRDVRDTLVSEAKKKTALKMKVNDAPMSKTMLSKVKVGDLRDAAKVLGLDQVMQGVTKKADVVAYLLAYYEYMHGTIDAKTMGVRMSDVSSISAEIMREAEKDSNATSASARSAKVSKPELKRETDPGRMDYVKAFEPDELVQLLVRARGIDVMSINVRDQCTWTDHLIIATARSAHHLKALAGAVLHAVKARTEYVAGGRLQPVIEGAQNGGDKDWMAVDCGSCMVHIFSPEGRAQYNLEELWATGEEIVHNGPERLSIDTIGADHHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4S596</accession>
    <name>A4S596_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420568.1">
        <property type="nucleotide sequence ID" value="XM_001420531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S596"/>
    <dbReference type="GeneID" id="5004805"/>
    <dbReference type="Gramene" id="ABO98861">
        <property type="protein sequence ID" value="ABO98861"/>
        <property type="gene ID" value="OSTLU_26684"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26684"/>
    <dbReference type="HOGENOM" id="CLU_3127595_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="50" mass="5409" checksum="BA71805FEB535DE0" modified="2007-05-15" version="1">MRTEIETRYERLKALVVVNTRHLDAGRGGEAREGAEPNDVTQLSAGGGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5P7</accession>
    <name>A4S5P7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26838</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420647.1">
        <property type="nucleotide sequence ID" value="XM_001420610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5P7"/>
    <dbReference type="STRING" id="436017.A4S5P7"/>
    <dbReference type="GeneID" id="5004907"/>
    <dbReference type="Gramene" id="ABO98940">
        <property type="protein sequence ID" value="ABO98940"/>
        <property type="gene ID" value="OSTLU_26838"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26838"/>
    <dbReference type="eggNOG" id="ENOG502RIEW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1091503_0_0_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044841">
        <property type="entry name" value="LUX/BOA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442:SF29">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="106"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="255" mass="27603" checksum="E471C58B0B4933BD" modified="2007-05-15" version="1">MTVYPAVYGAYDAMRAMSPMTYDAYAGAARAVAVPGDSFSRQIQERAYASAFTFTRQWNYLQHAAAAQHAAFASGSRGGGTMMDLLAATGSAAAERDIGVEREVELSKRQRLVWTPQLHAQFIAAVQKLGVKTAVPKAIMKIMNVKGLTRENVASHLQKYRLTLKRAQDSSESTRASGDATDAKRSDVRAGRKRKDREEKGKTNSGSGQGSGQGSDGGSAEHSASENLENRAKRISSSEEEETRQITLAVDHNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5T6</accession>
    <name>A4S5T6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420666.1">
        <property type="nucleotide sequence ID" value="XM_001420629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5T6"/>
    <dbReference type="GeneID" id="5004927"/>
    <dbReference type="Gramene" id="ABO98959">
        <property type="protein sequence ID" value="ABO98959"/>
        <property type="gene ID" value="OSTLU_26877"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26877"/>
    <dbReference type="HOGENOM" id="CLU_2310844_0_0_1"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="100" mass="10742" checksum="E2FB833A24F1E4B7" modified="2007-05-15" version="1">MHPDQATDAAVDFALERNLPFAVVPCCVYAKEFGKRRLADGSRVTTHAHLVDHLVQKAGLTDVRVAELPFPGKNVVVYGTGRRASTCVAVQTPQRGGVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5W2</accession>
    <name>A4S5W2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420840.1">
        <property type="nucleotide sequence ID" value="XM_001420803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5W2"/>
    <dbReference type="STRING" id="436017.A4S5W2"/>
    <dbReference type="GeneID" id="5004879"/>
    <dbReference type="Gramene" id="ABO99133">
        <property type="protein sequence ID" value="ABO99133"/>
        <property type="gene ID" value="OSTLU_26902"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26902"/>
    <dbReference type="HOGENOM" id="CLU_383291_0_0_1"/>
    <dbReference type="OMA" id="DYKRDHK"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="680"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="722" mass="66094" checksum="233346D589A78116" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5W5</accession>
    <name>A4S5W5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420842.1">
        <property type="nucleotide sequence ID" value="XM_001420805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5W5"/>
    <dbReference type="STRING" id="436017.A4S5W5"/>
    <dbReference type="GeneID" id="5004881"/>
    <dbReference type="Gramene" id="ABO99135">
        <property type="protein sequence ID" value="ABO99135"/>
        <property type="gene ID" value="OSTLU_26905"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26905"/>
    <dbReference type="eggNOG" id="ENOG502QT89">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060552_1_0_1"/>
    <dbReference type="OMA" id="QSSSEMF"/>
    <dbReference type="OrthoDB" id="510307at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04692">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF20">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="216" mass="23749" checksum="A09831F175593B47" modified="2007-05-15" version="1">MFEVMAPPGDDFDAFVDAPTPTGAVKRRADVHADGDWHRSAHVWLVDARTRSVVVQKRSAMKDTFPGAWDVGAAGHVGAEDGGSSRRTARHELAEELGVELEREDALVFQFTVPAAQASFGGCNCFEDVYFARWTRRDEGEDDEDEFAIGLAEVTATKWIEFDALERALADAAARVDAVGAKGPYEYVPRSPLYRELFFERLRAFVADADCDATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S615</accession>
    <name>A4S615_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_7755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420709.1">
        <property type="nucleotide sequence ID" value="XM_001420672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S615"/>
    <dbReference type="STRING" id="436017.A4S615"/>
    <dbReference type="GeneID" id="5004853"/>
    <dbReference type="Gramene" id="ABO99002">
        <property type="protein sequence ID" value="ABO99002"/>
        <property type="gene ID" value="OSTLU_7755"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7755"/>
    <dbReference type="eggNOG" id="KOG3154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035060_4_2_1"/>
    <dbReference type="OMA" id="DCSWESA"/>
    <dbReference type="OrthoDB" id="10262062at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106388">
        <property type="term" value="F:rRNA small subunit aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002621">
        <property type="entry name" value="PRK02287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426:SF0">
        <property type="entry name" value="18S RRNA AMINOCARBOXYPROPYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase L inhibitor RLI-like possible metal-binding" evidence="7">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal" evidence="6">
        <location>
            <begin position="44"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20471" checksum="16F7474B0AF5EC74" modified="2007-05-15" version="1" fragment="single">PTRFPVPLAMWDLAQCDPKRCSGRKLARLGCLRELRVQQRWAGVALTPNATETISPKDYEVLNANGLAVVDCSWNRLDDVPFQRLHSAAPRLLPWLVAANPVNYGKPCKLTCAEALAGGLYIAGYRDAAEALMNKFKWGHGFISLNRELLESYMQCRTSEEVIETQNKWLTLGGPEAAPRRDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S690</accession>
    <name>A4S690_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">OSTLU_17763</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421050.1">
        <property type="nucleotide sequence ID" value="XM_001421013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S690"/>
    <dbReference type="STRING" id="436017.A4S690"/>
    <dbReference type="GeneID" id="5005110"/>
    <dbReference type="Gramene" id="ABO99343">
        <property type="protein sequence ID" value="ABO99343"/>
        <property type="gene ID" value="OSTLU_17763"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17763"/>
    <dbReference type="eggNOG" id="KOG2788">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029942_0_1_1"/>
    <dbReference type="OMA" id="LPHFNAR"/>
    <dbReference type="OrthoDB" id="10262326at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABO99343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="39168" checksum="21B05AD8D76818DC" modified="2007-05-15" version="1">MRLLPTVGAKTLARNMSGYDLNKKGTALGERRVPESGGLAAGCAYAVALTMQQLCQRGIRWWFGQSASGTNAWALEQNSALACVGFMIFLGFVDDVLDLPWRVKIVMPGFAALPLLLSYSGGTTVLIPSPVRALLELPAGVRSIDVGPLYLCYMWLLVVFCSNSINIHAGLNGLEAGQSLIIAGAILLLNVLSLANDPSTEPVTAGAHLFSIFLTLPFFATTLALLRHNWYPSKIFVGDTYTYFAGMTLGVVGTLGHFSETLLLFFLPQVLNFVYSTPQLFKIVHCPRHRLPIFDPKTGLLHPSMATETRYNMNLVTLFLRLFGPCTERVLCARLLAFQFLSCAFAFVARHALTGVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="107" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6B4</accession>
    <name>A4S6B4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC(ABCB) family transporter: mitochondrial ATM1-like protein (ABCB)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_13171</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421064.1">
        <property type="nucleotide sequence ID" value="XM_001421027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6B4"/>
    <dbReference type="SMR" id="A4S6B4"/>
    <dbReference type="STRING" id="436017.A4S6B4"/>
    <dbReference type="GeneID" id="5005022"/>
    <dbReference type="Gramene" id="ABO99357">
        <property type="protein sequence ID" value="ABO99357"/>
        <property type="gene ID" value="OSTLU_13171"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13171"/>
    <dbReference type="eggNOG" id="KOG0057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_1_1"/>
    <dbReference type="OMA" id="VFHIIPI"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18582">
        <property type="entry name" value="ABC_6TM_ATM1_ABCB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000221">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF402">
        <property type="entry name" value="IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="18"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="354"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="622"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="645" mass="69653" checksum="07481CF64D131395" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6C2</accession>
    <name>A4S6C2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_377</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS35L family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420916.1">
        <property type="nucleotide sequence ID" value="XM_001420879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6C2"/>
    <dbReference type="STRING" id="436017.A4S6C2"/>
    <dbReference type="GeneID" id="5005028"/>
    <dbReference type="Gramene" id="ABO99209">
        <property type="protein sequence ID" value="ABO99209"/>
        <property type="gene ID" value="OSTLU_377"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_377"/>
    <dbReference type="eggNOG" id="KOG3682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012270_0_0_1"/>
    <dbReference type="OMA" id="RVEVCKN"/>
    <dbReference type="OrthoDB" id="1734063at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029705">
        <property type="entry name" value="VPS35L"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13673">
        <property type="entry name" value="ESOPHAGEAL CANCER ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13673:SF0">
        <property type="entry name" value="VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="737" mass="82339" checksum="AA8DD9FAB9A6B1DB" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6I1</accession>
    <name>A4S6I1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27128</name>
        <name evidence="3" type="ORF">OSTLU_29781</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420947.1">
        <property type="nucleotide sequence ID" value="XM_001420910.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422947.1">
        <property type="nucleotide sequence ID" value="XM_001422910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6I1"/>
    <dbReference type="STRING" id="436017.A4S6I1"/>
    <dbReference type="GeneID" id="5004954"/>
    <dbReference type="GeneID" id="5006915"/>
    <dbReference type="Gramene" id="ABO99240">
        <property type="protein sequence ID" value="ABO99240"/>
        <property type="gene ID" value="OSTLU_27128"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01306">
        <property type="protein sequence ID" value="ABP01306"/>
        <property type="gene ID" value="OSTLU_29781"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27128"/>
    <dbReference type="KEGG" id="olu:OSTLU_29781"/>
    <dbReference type="eggNOG" id="ENOG502S36G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_772409_0_0_1"/>
    <dbReference type="OMA" id="IFVSTHG"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086:SF10">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="135"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="206"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="344" mass="37768" checksum="A768A9C6559CBDAD" modified="2007-05-15" version="1">MHVTNVGGSLTTAVCLSLIAWSVRVLRSAKHRDRARQRTTSSSQPTVKLNKQTYGVLSAKAFWMLVQTKPVKYLLLDVRPKSEDGGATAVTKLSDRLAVTHILPEELANLLRNRNTLWKKRFPNIPVPSLRTTMIFVSTHGHSSSHAAALATSLGFTRCSIVDGGLAAAVPLAHFDEPAVFSSGKDRALSFDAVLLLLETVRDDGNALGLVILDIRRFDERALYGTLEGSTHVPVDHLPKAVHMNDEEWVRMFRFHKPTSDNLILLHSRSSSSAAWAKQLLSDAGLHNCHSYVDGAYAGPDGTLRSYEAYEEGGAPPEPVSIGQSVTFNRTSAERELLNLRIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="112" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6I5</accession>
    <name>A4S6I5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_51201</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421099.1">
        <property type="nucleotide sequence ID" value="XM_001421062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6I5"/>
    <dbReference type="STRING" id="436017.A4S6I5"/>
    <dbReference type="GeneID" id="5005156"/>
    <dbReference type="Gramene" id="ABO99392">
        <property type="protein sequence ID" value="ABO99392"/>
        <property type="gene ID" value="OSTLU_51201"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51201"/>
    <dbReference type="eggNOG" id="KOG0554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_0_1"/>
    <dbReference type="OMA" id="PEMAFYD"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000016">
        <property type="entry name" value="Asparagine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003037">
        <property type="entry name" value="PRK03932.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="166"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="503" mass="56368" checksum="6AC098A53CC743FB" modified="2007-05-15" version="1">MRARATPGAIKHARSARAVATRATYGRPERIARVKGNDGGASRVGEALELRGWARSVRTQKGMAFIDLNDGSAISGMQAVVNEGSAAWDALDAGGVSTGAALRVKGKLVASPGGKQAAELAVEEIDVIGTADPETYPLQKKRHTLEYLRSIAHLRPRTNTIGAVARVRNQLAYATHTFFQEHGFLYANTPIITASDCEGAGEQFQVTTLVEALKNNRPSSDLPKNKDGSIDYSQDFFGKPSYLTVSGQLNGEIMACAVNDIYTFGPTFRAENSNTSRHLAEFWMVEPELAFADLNDDMDCAEAYLKYCLNHVLEHCDEDLEFFEKNISKDNLRERLRNVASQEFARITYTEAVEHVLNAKKKFEFPIEWGSDLQSEHERYISEEVFKDRPVIVRDYPKDIKAFYMRLNDDNKTVAAMDVLVPRVGELMGGSQREERLDVLERRIEEVGLEKESYWWYLDLRRYGSQPHAGFGLGFERLVQYVTGVENIRDAIPFPRYPGSAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6K7</accession>
    <name>A4S6K7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93613</name>
        <name evidence="2" type="ORF">OSTLU_94166</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421108.1">
        <property type="nucleotide sequence ID" value="XM_001421071.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422846.1">
        <property type="nucleotide sequence ID" value="XM_001422809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6K7"/>
    <dbReference type="STRING" id="436017.A4S6K7"/>
    <dbReference type="GeneID" id="5005169"/>
    <dbReference type="GeneID" id="5006990"/>
    <dbReference type="Gramene" id="ABO99401">
        <property type="protein sequence ID" value="ABO99401"/>
        <property type="gene ID" value="OSTLU_93613"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01205">
        <property type="protein sequence ID" value="ABP01205"/>
        <property type="gene ID" value="OSTLU_94166"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93613"/>
    <dbReference type="KEGG" id="olu:OSTLU_94166"/>
    <dbReference type="HOGENOM" id="CLU_774752_0_0_1"/>
    <dbReference type="OMA" id="IERDSCA"/>
    <dbReference type="OrthoDB" id="500100at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030681">
        <property type="term" value="C:multimeric ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000171">
        <property type="term" value="F:ribonuclease MRP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013893">
        <property type="entry name" value="RNase_P_Rpp40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15396">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15396:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08584">
        <property type="entry name" value="Ribonuc_P_40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="39660" checksum="BA5905ABE3459657" modified="2007-05-15" version="1">MARRAQWRSFAHAKCDVDDALATTFALAKSVEVAVPRGRRDDEDAIARALDDDANAIVGTHFEAEMSIADALDPHFVHEHVRRWTAAKTKTRDAGATFGLTTIDAEVDSDDCFCVTPKGRFVASLMADAKESLGMQTTEDARGKALASVNLTREEFKVGNWFHDRIGACARAFEQRTGKSKVLCAYMVSGAHEEVKFPRTVTAARRAESVKTSSQVRVNLVSQSAVLLASASPPMRGEEKDIDVDDLDRILEFCGRISLGDAYMEGAEDDRGDIVETRRWRGLMLYPDTRRVIDIARRIVNDGLAPWAVVTVWAFAHMPSELTGEPRKKIERDSCAPKMGAVFTIVLYPDDKYLKFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6R4</accession>
    <name>A4S6R4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_19207</name>
        <name evidence="3" type="ORF">OSTLU_27212</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421138.1">
        <property type="nucleotide sequence ID" value="XM_001421101.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422817.1">
        <property type="nucleotide sequence ID" value="XM_001422780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6R4"/>
    <dbReference type="GeneID" id="5004994"/>
    <dbReference type="GeneID" id="5006964"/>
    <dbReference type="Gramene" id="ABO99431">
        <property type="protein sequence ID" value="ABO99431"/>
        <property type="gene ID" value="OSTLU_27212"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01176">
        <property type="protein sequence ID" value="ABP01176"/>
        <property type="gene ID" value="OSTLU_19207"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19207"/>
    <dbReference type="KEGG" id="olu:OSTLU_27212"/>
    <dbReference type="HOGENOM" id="CLU_1613560_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="2">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18697" checksum="79202479C419581B" modified="2007-05-15" version="1">MPSGCVYEMFSDNAKCNKTYIGSTTGSLRARLASHKYARHPIFTFGDADVRVLEKDIPAGELHQRKGAYMREKRDGLFNSRAAGRSQKHACRENVDESPAYSRAQYTPKRDGGDGNYRQLNYYKQHAKGILRKTCLKNARARGTLPSKRSLDKYQFTVDELRGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S752</accession>
    <name>A4S752_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_27354</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421211.1">
        <property type="nucleotide sequence ID" value="XM_001421174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S752"/>
    <dbReference type="STRING" id="436017.A4S752"/>
    <dbReference type="GeneID" id="5005399"/>
    <dbReference type="Gramene" id="ABO99504">
        <property type="protein sequence ID" value="ABO99504"/>
        <property type="gene ID" value="OSTLU_27354"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27354"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_6_1"/>
    <dbReference type="OMA" id="PGTCLRE"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07837">
        <property type="entry name" value="STKc_CdkB_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000375">
        <property type="entry name" value="Cell division related protein kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000281">
        <property type="entry name" value="Cyclin-dependent kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="10"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO99504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="329" mass="37797" checksum="69C3397C1D4FDE30" modified="2007-05-15" version="1">MGGHSINDAYEKLEKIGQGTYGKVYKARERANGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSESPYIVRLLRVEHVEEDGKAMLYLVFEFLDQDLKQYMDMTGRGPTNPLPTSVVQNYMYQLCLGCAHLHKHGVMHRDLKPQNMLVDKAKNLLKIADLGLGRAFSVPVKSYTHEIVTLWYRAPEVLLGGSHYSTPVDMWSVGCMFAEMARKQPLFPGDSELQQLLHIFKLLGTPSEQTWPGVSNLRDWHEFPQWKPQDLSKVIPQLDEHGIDLLSKLLVYDPAKRIHATDALEHPYFDSLDKSQFEQIEREFEIEFAQEKENRMAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S765</accession>
    <name>A4S765_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">O-acetylserine sulfhydrylase/homocysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CYSD</name>
        <name evidence="7" type="ORF">OSTLU_27367</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421219.1">
        <property type="nucleotide sequence ID" value="XM_001421182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S765"/>
    <dbReference type="STRING" id="436017.A4S765"/>
    <dbReference type="GeneID" id="5005486"/>
    <dbReference type="Gramene" id="ABO99512">
        <property type="protein sequence ID" value="ABO99512"/>
        <property type="gene ID" value="OSTLU_27367"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27367"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_4_0_1"/>
    <dbReference type="OMA" id="MTENWSF"/>
    <dbReference type="OrthoDB" id="494483at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="434" mass="46486" checksum="F6119787A53AE5D8" modified="2007-05-15" version="1">MPAPELKFETLQVHAGQASDPATNARAVPIYATSSYTFDSSKHGADLFGLRAFGNIYSRIMNPTCDVFEKRVAALEGGVGALAVSSGQSAQFLAISTICGTGDNIVATPSLYGGTYNQFKVTFPRLGINVKFAKDDDPASFEAQIDSNTKALYVETIGNPRFSVPDFAKLKAIAQKAGIPLICDNTFGACGYVCQPLKHGADIVVESATKWIGGHGTTVGGVIVDGGTMNWNNGKHPVMTDPSPGYHGLKFWDTFGPDGILGANATFIMRCRVEGLRDLGMCQNPFGAFNFILGLETLSLRMERHCSNTMALAQYLEKHPQVSWVSYPGLKAHPFHKLAIEYFRDGNFGAVLTFGIKGGLDAGMKFIDNVKLASHLANVGDAKTLVIHPASTTHEQLTPEEQTASGVTPDMIRVSVGIEHIDDICADFAQALTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7B9</accession>
    <name>A4S7B9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_13257</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421246.1">
        <property type="nucleotide sequence ID" value="XM_001421209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7B9"/>
    <dbReference type="STRING" id="436017.A4S7B9"/>
    <dbReference type="GeneID" id="5005513"/>
    <dbReference type="Gramene" id="ABO99539">
        <property type="protein sequence ID" value="ABO99539"/>
        <property type="gene ID" value="OSTLU_13257"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13257"/>
    <dbReference type="eggNOG" id="KOG1394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_1"/>
    <dbReference type="OMA" id="YKECHET"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000018">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF332">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="9">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="412" mass="43326" checksum="407A8B1432B08229" modified="2007-05-15" version="1">MGAVTAHGDDVDEMYEKLCRGESAIATIDKWDTGEIGTKFAGEIKAFDCGDYMNKKMARRVDPYIAYMIVAAKRALESAKVNWNDESGEHYVDKALSGCLIGSAMGGMQTFATATENLVTQGHRKMNPFCIPFAITNMGSALTAMDIGFMGPNYSIASACATGNFCILNSIMHIQNGEANLMLAGASDAAVIPIGMAGFSAAKALSTRNDDPAAASRPWDANRDGFVMGEGAGVLVLESLESALARGAPIVAEVLGGFATCDAHHMTEPRPDGVGVNFAIDKALEMTGVKAEDVNYINAHATSTPAGDMAELRVLQKKFKASGAKINSTKSLIGHLLGAASAVEAVVCIKAITSGEVHPNKNLETPDEGVDTSMLVGTTREKLDVKVALSNSFGFGGHNSAVLFAPYKPKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7P0</accession>
    <name>A4S7P0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic</fullName>
            <ecNumber evidence="9">1.3.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_27566</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>protochlorophyllide a + NADP(+) = 3,8-divinyl protochlorophyllide a + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48884"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58632"/>
            <dbReference type="ChEBI" id="CHEBI:83350"/>
            <dbReference type="EC" id="1.3.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.3.1.75" evidence="9"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421306.1">
        <property type="nucleotide sequence ID" value="XM_001421269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7P0"/>
    <dbReference type="STRING" id="436017.A4S7P0"/>
    <dbReference type="GeneID" id="5005280"/>
    <dbReference type="Gramene" id="ABO99599">
        <property type="protein sequence ID" value="ABO99599"/>
        <property type="gene ID" value="OSTLU_27566"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27566"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043999_0_0_1"/>
    <dbReference type="OMA" id="ASFIVDC"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="UniPathway" id="UPA00668"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033728">
        <property type="term" value="F:3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05243">
        <property type="entry name" value="SDR_a5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044201">
        <property type="entry name" value="DVR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47378">
        <property type="entry name" value="DIVINYL CHLOROPHYLLIDE A 8-VINYL-REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47378:SF1">
        <property type="entry name" value="DIVINYL CHLOROPHYLLIDE A 8-VINYL-REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="12">
        <location>
            <begin position="59"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="381" mass="40964" checksum="FEB3FF7AE9A9AEE1" modified="2007-05-15" version="1">MRATAGALGGARARCERAIGARSVTKTRSARRGGRATRAASAAELASEENKDVKVLVVGATGYIGKYVTRELCARGYDVTAFTREKSGIGGKTNATDAKALFPDAKVKFGDVGSKESIETKAFDEGAYDVVVSCLASRTGGVKDSWDIDYRATKNVLDVARERGSKHFVLLSAICVQKPTLTFQKAKLKFEAELQAAGDISYTIVRPTAFFKSLAGQVEVVQKGGPYVMFGDGQLASCKPISESDLAKFMADSIREPEMLNKVLPIGGPGEAMSALQQGTMLFELLEMEPKFIKVPIEVMDVAIKVLDVFAGFFSNMKDAAEFGKIGRYYAAESMLVMNDDGKYDAAATPSYGSDTLKEFFDKVSKEGLAGQELGDQAVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Q6</accession>
    <name>A4S7Q6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS24</name>
        <name evidence="6" type="ORF">OSTLU_42986</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421313.1">
        <property type="nucleotide sequence ID" value="XM_001421276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Q6"/>
    <dbReference type="STRING" id="436017.A4S7Q6"/>
    <dbReference type="GeneID" id="5005289"/>
    <dbReference type="Gramene" id="ABO99606">
        <property type="protein sequence ID" value="ABO99606"/>
        <property type="gene ID" value="OSTLU_42986"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42986"/>
    <dbReference type="eggNOG" id="KOG3424">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107248_1_0_1"/>
    <dbReference type="OMA" id="IRVKKYM"/>
    <dbReference type="OrthoDB" id="10251131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="130" mass="14834" checksum="2BA5532D882526AA" modified="2007-05-15" version="1" fragment="single">DAMTNTSCTIRTRKFMTNRLLQRRQFILDVLHPGRANVAKAELQEKLAKMYNVSDEKCVSIFGFRTAFGGGKSTGFGLIYDNLDAFKKFEPKHRLIRAGLKDAVQKSRKNIKEKKNRVKKLRGGAKNKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7S0</accession>
    <name>A4S7S0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DDRGK domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_27596</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421503.1">
        <property type="nucleotide sequence ID" value="XM_001421466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7S0"/>
    <dbReference type="STRING" id="436017.A4S7S0"/>
    <dbReference type="GeneID" id="5005295"/>
    <dbReference type="Gramene" id="ABO99796">
        <property type="protein sequence ID" value="ABO99796"/>
        <property type="gene ID" value="OSTLU_27596"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27596"/>
    <dbReference type="eggNOG" id="KOG3054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059562_3_1_1"/>
    <dbReference type="OMA" id="DHIMASK"/>
    <dbReference type="OrthoDB" id="2285710at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044389">
        <property type="term" value="F:ubiquitin-like protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019153">
        <property type="entry name" value="DDRGK_dom-contain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050899">
        <property type="entry name" value="DDRGK_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48176">
        <property type="entry name" value="DDRGK DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48176:SF1">
        <property type="entry name" value="DDRGK DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09756">
        <property type="entry name" value="DDRGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01128">
        <property type="entry name" value="DDRGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20705" checksum="A816B530A4BE52B4" modified="2007-05-15" version="1">MRARAEAEAEAEAAAQREQRGLTWKEQKEEKYRRKWAEREAKDRAEMEAAAAARAERRRLEDKQRGTRRGLFGGKEASSADETSANESEEALVAFADEIKTKKVVVLEELAAKFGLRTADAVRRVRMLEAEGRITGIMDDRGTFIYVSREEMERVAAFITEKGRVRIAELTRESAEILGLGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S801</accession>
    <name>A4S801_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_25572</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the P2X receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421542.1">
        <property type="nucleotide sequence ID" value="XM_001421505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S801"/>
    <dbReference type="GeneID" id="5005447"/>
    <dbReference type="Gramene" id="ABO99835">
        <property type="protein sequence ID" value="ABO99835"/>
        <property type="gene ID" value="OSTLU_25572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25572"/>
    <dbReference type="eggNOG" id="ENOG502T10T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_461062_0_0_1"/>
    <dbReference type="OMA" id="ITHEFET"/>
    <dbReference type="OrthoDB" id="498185at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031164">
        <property type="term" value="C:contractile vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035381">
        <property type="term" value="F:ATP-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070588">
        <property type="term" value="P:calcium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.940">
        <property type="entry name" value="atp-gated p2x4 ion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059116">
        <property type="entry name" value="P2X_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10125">
        <property type="entry name" value="P2X PURINOCEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10125:SF31">
        <property type="entry name" value="P2X RECEPTOR E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="599" mass="65939" checksum="8A09703D70B8FBEE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S894</accession>
    <name>A4S894_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_27769</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421724.1">
        <property type="nucleotide sequence ID" value="XM_001421687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S894"/>
    <dbReference type="STRING" id="436017.A4S894"/>
    <dbReference type="GeneID" id="5005624"/>
    <dbReference type="Gramene" id="ABP00018">
        <property type="protein sequence ID" value="ABP00018"/>
        <property type="gene ID" value="OSTLU_27769"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27769"/>
    <dbReference type="eggNOG" id="KOG2261">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036027_0_0_1"/>
    <dbReference type="OMA" id="REVTHAH"/>
    <dbReference type="OrthoDB" id="435275at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="9">
        <location>
            <begin position="34"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="221"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="484" mass="55170" checksum="897DD83A65A23707" modified="2007-05-15" version="1">MATRQTSFRARPIDITSQLALLRDPDAIKDEQVVQREVTHAHKALDKENEEVLTKETTTGVSEIPIPEILNVSSYESDYPTNYKQPDYYLRSKLTCGLPPTETTSYVEYDLDNEDEDWLENYNDGSEVLSAEKFEEMLWKLELACAEANEKIMKANTAMAAARGQVISYQEKVDALGVVTNLPKDKALELLQEISGKQAILTAVYEYWTDRRQRLKKPLLRRLQPPPAPNDSNPFNVFRPREKISRPQTRRRRENDVTSYDKLRQLRKSLDISIGVLELVVKREKRKSELLTVEQELQKLQIKLRHEPKASLEAIEQKVMEADKKRFKTETPEIPPNKNIVLAGGAVELIKKPDGQYVVLGDDMGDLAGRKRRRELGLAALGGYAPRPRVQIPVLPYQPPPEIPDIEMLFTKSPSMAAVRTFLLPLGVNLKQCRPRYGRSGRIIFDRKDPITREAFSVDSDDEMDSDDDGNNPFLIRSAFAVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8A1</accession>
    <name>A4S8A1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421730.1">
        <property type="nucleotide sequence ID" value="XM_001421693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8A1"/>
    <dbReference type="GeneID" id="5005667"/>
    <dbReference type="Gramene" id="ABP00024">
        <property type="protein sequence ID" value="ABP00024"/>
        <property type="gene ID" value="OSTLU_27776"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27776"/>
    <dbReference type="HOGENOM" id="CLU_1241867_0_0_1"/>
    <dbReference type="OMA" id="RARQFCP"/>
    <dbReference type="OrthoDB" id="10578932at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="223" mass="24766" checksum="12BBB288FA438145" modified="2007-05-15" version="1">MDACSVIYGAAKPGEDEWGRRAREVDEDGDASAAAASGDSDVDDEDDERDDDEDAVIADEEFKAGVRALKRGDLNEALRRFVYAESCCPRSMTEAKEKLLKTIAQTRALLEQEDEDEGDDDEFVSRDDDEFDDSRDFDDAGDEFHDAEGADSETGWSDTDASLADDAYRTAVWLLKSAADERKPADTEKIRDLLERARQFCPPAASEALHRIDDLLARLDVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8K7</accession>
    <name>A4S8K7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GOST seven transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_89323</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421640.1">
        <property type="nucleotide sequence ID" value="XM_001421603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8K7"/>
    <dbReference type="GeneID" id="5005720"/>
    <dbReference type="Gramene" id="ABO99933">
        <property type="protein sequence ID" value="ABO99933"/>
        <property type="gene ID" value="OSTLU_89323"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89323"/>
    <dbReference type="eggNOG" id="KOG2568">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029077_1_0_1"/>
    <dbReference type="OMA" id="WIAYEVY"/>
    <dbReference type="OrthoDB" id="19932at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053937">
        <property type="entry name" value="GOST_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF1">
        <property type="entry name" value="GH17801P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06814">
        <property type="entry name" value="GOST_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673135" description="GOST seven transmembrane domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="GOST seven transmembrane" evidence="8">
        <location>
            <begin position="229"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="548" mass="60829" checksum="5DE9E5AC9F10B832" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8P3</accession>
    <name>A4S8P3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_40439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421661.1">
        <property type="nucleotide sequence ID" value="XM_001421624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8P3"/>
    <dbReference type="STRING" id="436017.A4S8P3"/>
    <dbReference type="GeneID" id="5005800"/>
    <dbReference type="Gramene" id="ABO99954">
        <property type="protein sequence ID" value="ABO99954"/>
        <property type="gene ID" value="OSTLU_40439"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40439"/>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1880870_0_0_1"/>
    <dbReference type="OrthoDB" id="1893551at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF408">
        <property type="entry name" value="OS09G0560450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="22"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="78"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="16979" checksum="A936BDEAD249CEAC" modified="2007-05-15" version="1" fragment="single">MKANVSRVSTSKFHALAVDESGSVYAWGCARDGVLGFGRERGDEAVVFPTLVRSFGCDVRVVRVSAGLAHSAVTTDAFETFTWGNGALGRLGYSVAVDDSASDDERERERRCTQFTPRKVPNMAGARAVDVSCGDTFTAVLDADGAVWTMGSNARGALGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Y0</accession>
    <name>A4S8Y0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pentatrichopeptide repeat (PPR) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPR4</name>
        <name evidence="3" type="ORF">OSTLU_2458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421968.1">
        <property type="nucleotide sequence ID" value="XM_001421931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Y0"/>
    <dbReference type="STRING" id="436017.A4S8Y0"/>
    <dbReference type="GeneID" id="5005867"/>
    <dbReference type="Gramene" id="ABP00262">
        <property type="protein sequence ID" value="ABP00262"/>
        <property type="gene ID" value="OSTLU_2458"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2458"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_734867_0_0_1"/>
    <dbReference type="OMA" id="DACINAR"/>
    <dbReference type="OrthoDB" id="822380at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47931">
        <property type="entry name" value="OS01G0228400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47931:SF2">
        <property type="entry name" value="OS01G0228400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="137"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="286"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="321"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="377" mass="41341" checksum="544D5147698083E6" modified="2007-05-15" version="1" fragment="single">VGAYVSEGRVEEAERVLREMTAEGVRAGPRLFNTLITGYGREKNLRGVEASSMAMRTLGVTPNQATWGAKVNAYVSCDRLDLAMDTLEQGVRFSPRVERRPGVQAYTALVQGLAHSGRVVEADELLRRMARDGVKPNVYTYSTLIDGLAKSAQIGLAETALAEMRRAKIKPSVVTYNSLLKGVVRGIGKADRTDEVLRRAREMFDRMRDDGVPPDLVTYNTLIDACINARAPAEAWNILREISESGLKPDVVTYTTLLKYFVQVGDDSATQWVIAELETDPQVVEDVGVYNCLINAYARQGDMCRAVETLEGMKAKNITPNVSTYGSILEGYIRLGNVGEAFKVYNLCVKSAGLAPDARMRKSLIYGCGLHGMSDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S925</accession>
    <name>A4S925_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DFDF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_28052</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421860.1">
        <property type="nucleotide sequence ID" value="XM_001421823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S925"/>
    <dbReference type="STRING" id="436017.A4S925"/>
    <dbReference type="GeneID" id="5005889"/>
    <dbReference type="Gramene" id="ABP00154">
        <property type="protein sequence ID" value="ABP00154"/>
        <property type="gene ID" value="OSTLU_28052"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28052"/>
    <dbReference type="eggNOG" id="KOG1073">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019221_4_1_1"/>
    <dbReference type="OMA" id="WYPPPGH"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="4">
        <location>
            <begin position="284"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="5">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="127"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="256"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="372"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="83"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="394"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="42969" checksum="86369233FF181062" modified="2007-05-15" version="1">MDGSFIGSTIYLVSHSDIRYEGVLVNIDPVESTLTLQNVRSFGTEGRRTNGVQIPPSVEVYEYITFKGDDIQDLEIVENGASAAAQQQQHAQQPQYMQQPQYGQQPQYGQQPQYGYMGAPQQAYMGYPPQQQYGMPQQYGAPPPAWGQPPPQQQQPPPQPPMQQQPPVQQQQQQQPPAPAPKKSAWGNPNPAAAASEGVILPAARNAPPAAAGVAKTAATVAAPKAIAKAAAPKPKPTSFAAAALNAMAPEEVARLRAAPRPAPTQGGRGVPAPRTGGRGAGGGRGAAPAVPKEAFNFEKMLQKFNKEKLAQSAEAKKLTTEVQSNPVYVKDDFFDTMSSEATEKAAGGNRGRFHEQRRMDAMTFGFDAVSASHAAQRAAAAGRGGRGGRSDGGRGGGRGGGRGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9A5</accession>
    <name>A4S9A5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422028.1">
        <property type="nucleotide sequence ID" value="XM_001421991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9A5"/>
    <dbReference type="GeneID" id="5005932"/>
    <dbReference type="Gramene" id="ABP00322">
        <property type="protein sequence ID" value="ABP00322"/>
        <property type="gene ID" value="OSTLU_28136"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28136"/>
    <dbReference type="HOGENOM" id="CLU_1613561_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="105"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18257" checksum="3FF916B04ED8E0E5" modified="2007-05-15" version="1">MQHGASARPGRARDSREANWVGDEINRHVKLNADAGGPETPEVEVGSSLAEFGGMDNNQDAATEDYILRRRRRKRRAQRNKEAENERQIIKTTPAADDNDDAMQSARETLGVTEGATKREITKAFYKQAKLHHTDKVGPAGKEKMQEINAAKDLLLTASDNSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9B3</accession>
    <name>A4S9B3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FBP16-4</name>
        <name evidence="3" type="ORF">OSTLU_28144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422033.1">
        <property type="nucleotide sequence ID" value="XM_001421996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9B3"/>
    <dbReference type="STRING" id="436017.A4S9B3"/>
    <dbReference type="GeneID" id="5005935"/>
    <dbReference type="Gramene" id="ABP00327">
        <property type="protein sequence ID" value="ABP00327"/>
        <property type="gene ID" value="OSTLU_28144"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28144"/>
    <dbReference type="eggNOG" id="KOG0552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089785_1_0_1"/>
    <dbReference type="OMA" id="YGPNEVM"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044180">
        <property type="entry name" value="FKBP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47862">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP18, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47862:SF2">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="2">
        <location>
            <begin position="81"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="191" mass="19409" checksum="A34D634E9DE15DA6" modified="2007-05-15" version="1">MKTRPRASASASSDVARRRDALVGAALALVATPGAARAKLSGGVTGGVPIENFQPIPGTNPPILYYDLQGASGATGGVPKGARVAVHYDLKFRSVTVGTSRQGAGVTGGTPIGFTVGQPAGEPGGPFIQAFNEGIKGMGVGTVRRMIVPPEYAYGPNEVMEIPANGTVTLDLELLSVAKDPITRGVKGAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9D2</accession>
    <name>A4S9D2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Secretory carrier-associated membrane protein</fullName>
            <shortName evidence="6">Secretory carrier membrane protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_89451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Probably involved in membrane trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle</location>
            <location evidence="6">Secretory vesicle membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SCAMP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422044.1">
        <property type="nucleotide sequence ID" value="XM_001422007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9D2"/>
    <dbReference type="GeneID" id="5005943"/>
    <dbReference type="KEGG" id="olu:OSTLU_89451"/>
    <dbReference type="eggNOG" id="KOG3088">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066546_3_2_1"/>
    <dbReference type="OMA" id="CLAWFTG"/>
    <dbReference type="OrthoDB" id="242866at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055038">
        <property type="term" value="C:recycling endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030658">
        <property type="term" value="C:transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007273">
        <property type="entry name" value="SCAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10687:SF2">
        <property type="entry name" value="SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10687">
        <property type="entry name" value="SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04144">
        <property type="entry name" value="SCAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="220" mass="24724" checksum="49FBA0DE89E73CF8" modified="2007-05-15" version="1" fragment="single">LEVRERSARSGGGGKTPNWPFSFWAFTYHNISDEIHPQHRSCVKFCYTVYCVFALALVSNFFVAMARMFLHMDFAAFLMAFIYMVCGIPGAYMLWYRRVYNSCKTDRAFGFLWFFLMFMVHIGFVFFATLAPPNMFGAQKWSLCGILNLNEALQGNKTIGVMHTIVMLLFAADSVLSVLAIRWVYSSFRSGGHTLEQARAEAYREGIAAATTGGIGSAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9F1</accession>
    <name>A4S9F1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_28180</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422053.1">
        <property type="nucleotide sequence ID" value="XM_001422016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9F1"/>
    <dbReference type="STRING" id="436017.A4S9F1"/>
    <dbReference type="GeneID" id="5006093"/>
    <dbReference type="Gramene" id="ABP00347">
        <property type="protein sequence ID" value="ABP00347"/>
        <property type="gene ID" value="OSTLU_28180"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28180"/>
    <dbReference type="eggNOG" id="KOG0751">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061075_0_0_1"/>
    <dbReference type="OMA" id="RYGRMVC"/>
    <dbReference type="OrthoDB" id="44467at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="89"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="175"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="271" mass="28078" checksum="587C77FCB7E739A3" modified="2007-05-15" version="1">MARVPLSDAENLAVGAFGGIVETCVQMPLITFKICVQDSRALPRSIAGWYRGVFANAASLAPITAAQVAVNGAIERVITNGERGMSDAEQIGCAMAAGAVSSALYSPVDLTVIQQQKMGLGPGGTVAAVVKQGGLAKMWRGTVSCAARESIYTAGYLGLGPVLTNKIKEAQPNLGDFASSVLGASLAGTFAAGLTHPIDTSKTLMQSDLSGSKFTSATHALSETYKTGGIRALYKGGFARTVRICGAFFIVGNIREYAVNYKNANLTADET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9J0</accession>
    <name>A4S9J0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">(S)-ureidoglycine aminohydrolase cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422075.1">
        <property type="nucleotide sequence ID" value="XM_001422038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9J0"/>
    <dbReference type="GeneID" id="5006133"/>
    <dbReference type="Gramene" id="ABP00392">
        <property type="protein sequence ID" value="ABP00392"/>
        <property type="gene ID" value="OSTLU_18632"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18632"/>
    <dbReference type="HOGENOM" id="CLU_1043495_0_0_1"/>
    <dbReference type="OrthoDB" id="564081at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="28848" checksum="4B748F2EBB246297" modified="2007-05-15" version="1">MGGNASKQLVDENPLVTRCKFDDPTEVVVLPKAKIEKFDLKTALGMRVTVEPGWEWARDVGEAQGKKYCPVRHVGIVEQGQINVTTKDGAKMRYAAGDVYLIEPGHNAKNKQGVNFVGYEFVSKINTDAAGGGSTYAAEVASSEVEVKQLDKASFAAPSVSKTMPNGEACVCMLGNNQAKSMRATLQPGWTWKTGARTLLPPEKQTLEACPARHVGYITKGKFAMIDAKTGKTTIVAPGMCYVCEPGHDAEVLGDETVEFIEFETIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9P5</accession>
    <name>A4S9P5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC53 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422206.1">
        <property type="nucleotide sequence ID" value="XM_001422169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9P5"/>
    <dbReference type="STRING" id="436017.A4S9P5"/>
    <dbReference type="GeneID" id="5006162"/>
    <dbReference type="Gramene" id="ABP00523">
        <property type="protein sequence ID" value="ABP00523"/>
        <property type="gene ID" value="OSTLU_28270"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28270"/>
    <dbReference type="HOGENOM" id="CLU_1519852_0_0_1"/>
    <dbReference type="OrthoDB" id="268027at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019309">
        <property type="entry name" value="WASHC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015">
        <property type="entry name" value="PROTEIN AD-016-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015:SF0">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10152">
        <property type="entry name" value="CCDC53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="157" mass="15577" checksum="97A76906D08AD734" modified="2007-05-15" version="1">MASALNARAARTATTLDALCASAEAKLGAAARALREAEARTALLERALEAGTATTTTTTAEAATREDDGRGADAADAADAATAEAATATAAAATAATATAEAATAEAATAATPETNARASDPKYSIYFKMLKMGVPAQAVRNKMNLDGVDASVLDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9R5</accession>
    <name>A4S9R5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422218.1">
        <property type="nucleotide sequence ID" value="XM_001422181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9R5"/>
    <dbReference type="GeneID" id="5006170"/>
    <dbReference type="Gramene" id="ABP00535">
        <property type="protein sequence ID" value="ABP00535"/>
        <property type="gene ID" value="OSTLU_28289"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28289"/>
    <dbReference type="HOGENOM" id="CLU_2889878_0_0_1"/>
    <dbReference type="OrthoDB" id="2016729at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021262">
        <property type="entry name" value="DUF2839"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36347">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36347:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10999">
        <property type="entry name" value="DUF2839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="63" mass="7206" checksum="9D15947E4297297D" modified="2007-05-15" version="1">MWEADPAAWEETPAGERAWTVWTGEKGWMYWMNQASLYGAGGLAFFWVVFRFIGPAIGLYTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA64</accession>
    <name>A4SA64_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422324.1">
        <property type="nucleotide sequence ID" value="XM_001422287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA64"/>
    <dbReference type="GeneID" id="5006349"/>
    <dbReference type="Gramene" id="ABP00641">
        <property type="protein sequence ID" value="ABP00641"/>
        <property type="gene ID" value="OSTLU_28445"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28445"/>
    <dbReference type="HOGENOM" id="CLU_795442_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671954" description="Sulfotransferase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="39539" checksum="C860EA0C9D31B57B" modified="2007-05-15" version="1">MQARIFVIGCLIATWGSSIYLRNSGDDLVKRVAKHVIPTEYERSDIDAVRRFRTRQGQSVVYFVHLKKAGGTTLCSSMDASGAGVRGNRSCNCELVTSPTCGPDARAYGDFEQQQDLFSELTTGGRRVEFFGMEHPMSPHFNTSTERPWVYATAIRHPYDMYNSHIAHNVNYFRKSGYTAQQISELSATSYAARLASHSFRENLLMDTHRESVPGHIIFSLTGITRTDDIQSIATATSLKNTTQLATMTRDEIMALLLETAKERLRHFSAILVRETYDQDLRVFFQNLGVTNFTIDSSRSSNNTLRSVKDEDFYQGDVQVQAALYQKFKYDVELYEYAVELAKHINVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAH6</accession>
    <name>A4SAH6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF501 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422434.1">
        <property type="nucleotide sequence ID" value="XM_001422397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAH6"/>
    <dbReference type="GeneID" id="5006449"/>
    <dbReference type="Gramene" id="ABP00751">
        <property type="protein sequence ID" value="ABP00751"/>
        <property type="gene ID" value="OSTLU_28573"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28573"/>
    <dbReference type="HOGENOM" id="CLU_1191580_0_0_1"/>
    <dbReference type="OMA" id="GKEREMC"/>
    <dbReference type="OrthoDB" id="46395at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007511">
        <property type="entry name" value="DUF501"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37163">
        <property type="entry name" value="CONSERVED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37163:SF1">
        <property type="entry name" value="DUF501 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04417">
        <property type="entry name" value="DUF501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="25981" checksum="79BFDB6C6B28B50A" modified="2007-05-15" version="1">MPDGYLAHASPLRRADASTIDDARAVKRLDGSVDVLGVARRDARGNPTVLLCRPLRTQRARGDDERARRRARAKKWRGSTTVESPWPNALWLCDRELCRRVGRLEHGGGAAAARRKIDDDEATARIFDAQQRRYAAMRWGLLTGKEREMCERLGGEHVEALRDRGVGGYARDDVGGTGLLIQVKCLHAHYAHYLATDGDNVVGAMVQEMLDAGEDEDVARAQREEGERRKRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAN9</accession>
    <name>A4SAN9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-mRNA processing factor 4 (PRP4)-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_43856</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422467.1">
        <property type="nucleotide sequence ID" value="XM_001422430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAN9"/>
    <dbReference type="STRING" id="436017.A4SAN9"/>
    <dbReference type="GeneID" id="5006699"/>
    <dbReference type="Gramene" id="ABP00784">
        <property type="protein sequence ID" value="ABP00784"/>
        <property type="gene ID" value="OSTLU_43856"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43856"/>
    <dbReference type="eggNOG" id="KOG0272">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_20_1"/>
    <dbReference type="OMA" id="LNEPICY"/>
    <dbReference type="OrthoDB" id="540662at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="4">
        <location>
            <begin position="40"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="271"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="314"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="356"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="476" mass="51786" checksum="FDE79B4F447DC846" modified="2007-05-15" version="1">MTDAEDVELRGAAEIARKQREELVREFESRRRLRATHAPTHDADVRAMLRKYREPITLFGERESERRDRLRALLASLDARDGGELDDGAGTRTATDKYGATIVDEGEYNAHATQKETFYTEGTERLLECRIDIAEWSLPRAAKRVATQREARGKGGRKDERATIDAVVASTSGFQAQCSEIGDASRPICEVKFYNGGRNAVSASWSGEARKWACDVEGGKLTSELVIRASDHRITGIDAFDAGDGRARIVTGHADGSAAIWNADGSRAAELKGHASRCGRVAFHPHGGKYVATASFDATWRLWSAETGEELLCQEGHAKEVYDVAFHPDGSLAASVGLDAVGRVWDLRIGKSIAVLRGHVKQILSVDFSPNGYHVVTGGDDRTVKSWDLRKSAECAYTNAAHSALVSCVRYEKTSSNGAFFTSSSYDGSVVVYSARDFAPHKKIGDGAAGKLTAVDVAGDALILSGFDRTLKYYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAQ1</accession>
    <name>A4SAQ1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_94049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422649.1">
        <property type="nucleotide sequence ID" value="XM_001422612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAQ1"/>
    <dbReference type="STRING" id="436017.A4SAQ1"/>
    <dbReference type="GeneID" id="5006706"/>
    <dbReference type="Gramene" id="ABP00966">
        <property type="protein sequence ID" value="ABP00966"/>
        <property type="gene ID" value="OSTLU_94049"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94049"/>
    <dbReference type="eggNOG" id="ENOG502SAZ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF54">
        <property type="entry name" value="NUCLEAR TRANSPORT RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1003" mass="106532" checksum="BE4D427931DBFCB6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAT7</accession>
    <name>A4SAT7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PsbP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422662.1">
        <property type="nucleotide sequence ID" value="XM_001422625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAT7"/>
    <dbReference type="GeneID" id="5006719"/>
    <dbReference type="Gramene" id="ABP00979">
        <property type="protein sequence ID" value="ABP00979"/>
        <property type="gene ID" value="OSTLU_29376"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29376"/>
    <dbReference type="HOGENOM" id="CLU_1143911_0_0_1"/>
    <dbReference type="OrthoDB" id="498486at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="2">
        <location>
            <begin position="139"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="245" mass="27147" checksum="3077299BFD609723" modified="2007-05-15" version="1">MRASPIGARAATRAAPRRERRRDAKRSAAARARGSDDARAGATTTRRRFARGLQLSLLPLLAKDARARDEGDATKETRTFSVETRSFRVGNVPEYFEEIDLGDSASGKTYETLLRDKRFGLAGNTITLSKQTASSGGPRSLRDIGSIEDVAARLVDSENKKSRGKANAKLRVFAERRKDSIEYYDIVYEKNVLGVRRVIQCTLALDVDDAGSSTLYTLTVEEDAERYDDAEAEMRAVADGFKIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAV0</accession>
    <name>A4SAV0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein bS18c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRPS18</name>
        <name evidence="8" type="ORF">OSTLU_29387</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422503.1">
        <property type="nucleotide sequence ID" value="XM_001422466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAV0"/>
    <dbReference type="STRING" id="436017.A4SAV0"/>
    <dbReference type="GeneID" id="5006724"/>
    <dbReference type="Gramene" id="ABP00820">
        <property type="protein sequence ID" value="ABP00820"/>
        <property type="gene ID" value="OSTLU_29387"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29387"/>
    <dbReference type="eggNOG" id="KOG3162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148710_1_1_1"/>
    <dbReference type="OrthoDB" id="21463at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_bS18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_bS18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_bS18_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479:SF40">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="76" mass="8700" checksum="540FC61E68D25D33" modified="2007-05-15" version="1">MRGKAVEATLLERAAYEDARFLTQFVSDTGKIYPKRRLGVSAKAQRKIARAIKTARQMGILPYTSRLPQFQRSRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAX7</accession>
    <name>A4SAX7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_25847</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422681.1">
        <property type="nucleotide sequence ID" value="XM_001422644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAX7"/>
    <dbReference type="STRING" id="436017.A4SAX7"/>
    <dbReference type="GeneID" id="5006574"/>
    <dbReference type="Gramene" id="ABP00998">
        <property type="protein sequence ID" value="ABP00998"/>
        <property type="gene ID" value="OSTLU_25847"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25847"/>
    <dbReference type="HOGENOM" id="CLU_060015_0_0_1"/>
    <dbReference type="OMA" id="PIMKAAF"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="377" mass="41096" checksum="24B0D2707E052735" modified="2007-05-15" version="1">MVLAESSTTTTTTTTATTRRRARGRGAKIVLACACAIVVAVRARACEANFGWNGESDAATAADGETATANVVADAKREEVPVDVESVESVIKEKKRRKKSVKKAAKKPVEEEEFKPYDPELGEGESAIGSIHEAIDDDDMEELEDLLRWKPNLREKCQKLGETRHYVPIMKAAFLGNARAMDLLIDYGANVNEIDAIGYTVLMRSVLSKCAECVRILVEAGAVVNYVQKTPMMDLGLSAQKLAMLMGEREIAEILRNAGADELETGAEKKRRLQKEGAERFKEHVEAQGIDVDIDKLLNTTVDDLNVKNSQSGDVVVNVNGTNATMTHDETKDYRNLEEKIAQAKLKAEAEARAKEACASDAGDGSCAFDPTTKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB61</accession>
    <name>A4SB61_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422720.1">
        <property type="nucleotide sequence ID" value="XM_001422683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB61"/>
    <dbReference type="GeneID" id="5006619"/>
    <dbReference type="Gramene" id="ABP01037">
        <property type="protein sequence ID" value="ABP01037"/>
        <property type="gene ID" value="OSTLU_94088"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94088"/>
    <dbReference type="HOGENOM" id="CLU_1912079_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="14759" checksum="1FC8295A2F36D7EE" modified="2007-05-15" version="1" fragment="single">VRHMVSSSDHTRGKSQKPIGTSQLRPRGPDKYRCRKTSGTPGIAWFLYAFRADGENFSFSSFSQLFVEFGRDLSARMMDFASFEMVCDGLLAMVRRDFAPLDGANVAETFVTTRELHVLACPNFSSTSDADSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQC4</accession>
    <name>A4RQC4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-phosphofructo-2-kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_40330</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415710.1">
        <property type="nucleotide sequence ID" value="XM_001415673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQC4"/>
    <dbReference type="GeneID" id="4999561"/>
    <dbReference type="Gramene" id="ABO94002">
        <property type="protein sequence ID" value="ABO94002"/>
        <property type="gene ID" value="OSTLU_40330"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40330"/>
    <dbReference type="eggNOG" id="KOG0234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006383_0_1_1"/>
    <dbReference type="OMA" id="RWIQERC"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="58"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="506" mass="57790" checksum="B04C7AF4D10ED3EF" modified="2007-05-15" version="1">MGKQTSTSAPEERSATAKYAGGFPQTFGDFKDQFVTAENPTPQSIPPPKYGDQGIIGEKHVLIMVGLPARGKTHMAKRLCQYLRFFHGANTRVFNVGEYRRRDAGVGQTADYFTKENEEQRMKFARAALKDMIDFLFQEDSMSFLEQRGVDSGRVAIFDATNSTRERRRWLIEQIGTLPLKVLFIESICTDEAVVEKNVRMAKINNCDYSGVMTEEQAFKDFMQRVRNYEKEYEPMGSDDEVDLSFIKLIDCGRRVEFNRVHGFLLGRVAQFLSNMHATTCSIYLSRHGQSEYNSHGKIGGDSGLTPMGEAYAQKLAEFADRVITRDPENGEARPVRLWTSSLQRTKLTARHLKHDKVKTGGGKDWIQMAPRVLRNLDEIYAGVCDGMTYEEIRAAYPREYELRRQNKLSYRYPRGESYLDVIARLDPLVQELESYREDVLIVGHQGVLRLIYAYFAGLDRDEAATLSIPLNTVIKLTPRTHDCIEERVLLHDPSENQEPIDPPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQS8</accession>
    <name>A4RQS8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_39658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415439.1">
        <property type="nucleotide sequence ID" value="XM_001415402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQS8"/>
    <dbReference type="STRING" id="436017.A4RQS8"/>
    <dbReference type="GeneID" id="4999384"/>
    <dbReference type="Gramene" id="ABO93731">
        <property type="protein sequence ID" value="ABO93731"/>
        <property type="gene ID" value="OSTLU_39658"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39658"/>
    <dbReference type="eggNOG" id="KOG1867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008279_1_1_1"/>
    <dbReference type="OMA" id="CHEFFIA"/>
    <dbReference type="OrthoDB" id="47475at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF86">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="311" mass="34238" checksum="9951EB450E163456" modified="2007-05-15" version="1">MASAETLDVGAEMRCVMRTLMDGEYEAFPPHDLLRSVWRLVPSFAGNEQQDAHEFMRFLLDRLRKELSSGKHAGSQTNGLKGGLSPTSPKTPQGKCEQDDGVTGDKIMEIFGGVAVTTVTCMKCERSSERREPFMDLSLPIPPVVGKNGSIEEGEGPNGEATLQQCLAAFVRNETLSGHGRYFCDGCGKVQSATKSTRIAKLPPVLCLHLKRFTWKGHAMRTKLTHDVDFPLDDLDLAPYCETNGEAMYDLVAVVTHHGLNAGSGHYTACAREFTAEGNSDWQHFNDDDVNSLTAEEVRTGQGYIFLYARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQV5</accession>
    <name>A4RQV5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin heavy chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_28794</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the clathrin heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415454.1">
        <property type="nucleotide sequence ID" value="XM_001415417.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RQV5"/>
    <dbReference type="GeneID" id="4999874"/>
    <dbReference type="Gramene" id="ABO93746">
        <property type="protein sequence ID" value="ABO93746"/>
        <property type="gene ID" value="OSTLU_28794"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28794"/>
    <dbReference type="eggNOG" id="KOG0985">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002136_0_0_1"/>
    <dbReference type="OMA" id="HCYDLLH"/>
    <dbReference type="OrthoDB" id="2113814at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009506">
        <property type="term" value="C:plasmodesma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000001">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000005">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.110">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055358">
        <property type="entry name" value="CHCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015348">
        <property type="entry name" value="Clathrin_H-chain_linker_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016025">
        <property type="entry name" value="Clathrin_H-chain_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022365">
        <property type="entry name" value="Clathrin_H-chain_propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016341">
        <property type="entry name" value="Clathrin_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00637">
        <property type="entry name" value="Clathrin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09268">
        <property type="entry name" value="Clathrin-link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13838">
        <property type="entry name" value="Clathrin_H_link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01394">
        <property type="entry name" value="Clathrin_propel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002290">
        <property type="entry name" value="Clathrin_H_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50989">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clathrin heavy chain linker core motif" evidence="9">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="550"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="699"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="846"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="992"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1144"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1290"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1438"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1668"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1672"/>
            <end position="1688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO93746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1688" mass="189551" checksum="483095A01C14F229" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRJ6</accession>
    <name>A4RRJ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29039</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415580.1">
        <property type="nucleotide sequence ID" value="XM_001415543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRJ6"/>
    <dbReference type="STRING" id="436017.A4RRJ6"/>
    <dbReference type="GeneID" id="4999609"/>
    <dbReference type="Gramene" id="ABO93872">
        <property type="protein sequence ID" value="ABO93872"/>
        <property type="gene ID" value="OSTLU_29039"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29039"/>
    <dbReference type="eggNOG" id="KOG4624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142621_2_0_1"/>
    <dbReference type="OMA" id="ISIAWAC"/>
    <dbReference type="OrthoDB" id="6224010at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF5">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO93872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="10638" checksum="7B4292C30FB93019" modified="2007-05-15" version="1">MSPAPSVLKKEEEALITLMKERALVRCKTAQRTYYECVKGRTLSVAWACREQARAMSACLSEHTSDATLETMKARWTEAGKPSIADRGKIPKCFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRJ7</accession>
    <name>A4RRJ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1995 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415581.1">
        <property type="nucleotide sequence ID" value="XM_001415544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRJ7"/>
    <dbReference type="STRING" id="436017.A4RRJ7"/>
    <dbReference type="GeneID" id="4999385"/>
    <dbReference type="Gramene" id="ABO93873">
        <property type="protein sequence ID" value="ABO93873"/>
        <property type="gene ID" value="OSTLU_29040"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29040"/>
    <dbReference type="eggNOG" id="ENOG502QW2X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052261_1_0_1"/>
    <dbReference type="OMA" id="KSATWWE"/>
    <dbReference type="OrthoDB" id="2082at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044687">
        <property type="entry name" value="LPA3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34051">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34051:SF2">
        <property type="entry name" value="PROTEIN LPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1995" evidence="1">
        <location>
            <begin position="13"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="35918" checksum="3CE627BA5CFFAB39" modified="2007-05-15" version="1">MEERMEGRSTYAPESYTAMCMDAYASVRDCLNEGKTLIEVEFPAIPGEDADYKAASDVYIDANVQYALVVAQKLNAEMGKNVDVLVPDGIEYRRAKKIFENALGLSSAGVRLNVLDGRKSSMFGSAFGDMLGGKGLRTRKEEERDNDFDSADVFIVVNLSTIELESLEKFADETANGRPLIGLNLQLDTLRADLGLFSFPEKALHYRFLSRFTPAFYLRTRNYSRTINVSPFVINYSGAIFREYPAPWQVMIKQNNGVLACVAENEDRFTLAEAKEEMLIALGINDPDDSPMKKLRSGYKTSTWWEEECDDEDSDAWRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRM0</accession>
    <name>A4RRM0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL21m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PRPL21</name>
        <name evidence="5" type="ORF">OSTLU_29064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415593.1">
        <property type="nucleotide sequence ID" value="XM_001415556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRM0"/>
    <dbReference type="STRING" id="436017.A4RRM0"/>
    <dbReference type="GeneID" id="4999502"/>
    <dbReference type="Gramene" id="ABO93885">
        <property type="protein sequence ID" value="ABO93885"/>
        <property type="gene ID" value="OSTLU_29064"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29064"/>
    <dbReference type="eggNOG" id="KOG1686">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061463_3_0_1"/>
    <dbReference type="OMA" id="GRYYECH"/>
    <dbReference type="OrthoDB" id="5994at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000741">
        <property type="term" value="P:karyogamy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_bL21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_bL21"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO93885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="22445" checksum="51F853BCDED8C612" modified="2007-05-15" version="1">MSRHVARRAFSLATSVAPARAARAATAPSTSFARAVAAFAPSSSSPSPSPPLARAFASGLTINGGVTPAVDAVPESIVLVPREEAPAIDAERGVEVRPKDVFGVVEVRSHQFKVSPDDLIFVDKIKDVEVNDVVRLPRVLMLGSKTRTVIGRPTVPGAEVLALVEEHVRDGKKFIFKKKRRKNYRRMNGYRAQLTGLRVLEVRGIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS65</accession>
    <name>A4RS65_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415688.1">
        <property type="nucleotide sequence ID" value="XM_001415651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS65"/>
    <dbReference type="STRING" id="436017.A4RS65"/>
    <dbReference type="GeneID" id="4999798"/>
    <dbReference type="Gramene" id="ABO93980">
        <property type="protein sequence ID" value="ABO93980"/>
        <property type="gene ID" value="OSTLU_29260"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29260"/>
    <dbReference type="eggNOG" id="ENOG502QS3F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_583164_0_0_1"/>
    <dbReference type="OMA" id="RDECAPR"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052298">
        <property type="entry name" value="ZMYND10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13244">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13244:SF7">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="469" mass="51859" checksum="CFC85829049DFB4C" modified="2007-05-15" version="1">METLVVELARAETWRDECAPRMRAMSTPSSMTTTSYAIYLVRYHESVVCNLFELVLSGCSTSALDEVEDDVAAELADYCLRRIVWLSAREGGEKSDDDDDSASTTPDFTLSMSALAIARCLAASPRLLGQTRRDALAEALAPLLDSKPWIQRERHNSSIIKVYVDGSWTEDISEWDANTRVQKCEAQVWLALRSLLCDPAFAWDETRKSLAARVRKHLNESTIDQIPVLRDLKHVLDEVMVRNLDGVHVASRLAIEIVPKYRRALTQNGSAEYYESVAAIMLRERFDAIFMASIAEDILSTCEMTTDVAAKTTSAAPSSSSGDEAPVKIDILRERKTLDSASTSFDTVHVFEYDFAKDRAPNEVRAKTSHTRGLRRALASRSSNDGAEVELPCAFDGKIRVNFDARTITAPLTLRRSATTEDKPSVWITVGALAVDGFAAQLRLDRSPRGGDAYVVRDVHLTIAVTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSA9</accession>
    <name>A4RSA9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL11m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRPL11</name>
        <name evidence="8" type="ORF">OSTLU_30315</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416521.1">
        <property type="nucleotide sequence ID" value="XM_001416484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSA9"/>
    <dbReference type="STRING" id="436017.A4RSA9"/>
    <dbReference type="GeneID" id="5000244"/>
    <dbReference type="Gramene" id="ABO94814">
        <property type="protein sequence ID" value="ABO94814"/>
        <property type="gene ID" value="OSTLU_30315"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30315"/>
    <dbReference type="eggNOG" id="KOG3257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_1_2_1"/>
    <dbReference type="OMA" id="IMSFCKD"/>
    <dbReference type="OrthoDB" id="1091498at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000005">
        <property type="entry name" value="50S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000003">
        <property type="entry name" value="Mitochondrial ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_uL11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="7">
        <location>
            <begin position="10"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="6">
        <location>
            <begin position="73"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="152" mass="15981" checksum="85A1C1A90782D176" modified="2007-05-15" version="1">MSAKTPIALVRLVVPAGAAKPSPPVGPALGQHGVNIMSFCKDFNAKTSEHKSDVPVPVEIAIYGDKSFEWRMKTPPASYFIAKAAGVAKSSTRPGHAFVGSINLKHAYEIAKVKASDETMGHVGLESATKSVLGTARAMGIRVVDPRATNVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSI4</accession>
    <name>A4RSI4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acylneuraminate cytidylyltransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_36315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416486.1">
        <property type="nucleotide sequence ID" value="XM_001416449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSI4"/>
    <dbReference type="GeneID" id="5000251"/>
    <dbReference type="Gramene" id="ABO94779">
        <property type="protein sequence ID" value="ABO94779"/>
        <property type="gene ID" value="OSTLU_36315"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36315"/>
    <dbReference type="HOGENOM" id="CLU_042930_5_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008781">
        <property type="term" value="F:N-acylneuraminate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050793">
        <property type="entry name" value="CMP-NeuNAc_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21485">
        <property type="entry name" value="HAD SUPERFAMILY MEMBERS CMAS AND KDSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21485:SF6">
        <property type="entry name" value="N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23930" checksum="97B946F176927C75" modified="2007-05-15" version="1" fragment="single">MARIVAFVPCKGTSSRVESKNTKLLDSKPLFLHTLEKLLFECPFIDKVVLDSESDDVFKVAEFLASDNPKLVFLKRDEALATNKTDGNTLFMNEVERFDAEIYVQALCTSPFIHPETIKKGVESVMSGVYDSACTVRDDKLYTWTKAGPSYDIQNIPNSVDLPTTTVETMGLYNITRDAAKLTRRRIGNKPHMLHVTPEEAVDINYEVDFALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTH1</accession>
    <name>A4RTH1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-recycling factor, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosome-releasing factor, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_12187</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416314.1">
        <property type="nucleotide sequence ID" value="XM_001416277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTH1"/>
    <dbReference type="STRING" id="436017.A4RTH1"/>
    <dbReference type="GeneID" id="5000102"/>
    <dbReference type="Gramene" id="ABO94607">
        <property type="protein sequence ID" value="ABO94607"/>
        <property type="gene ID" value="OSTLU_12187"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12187"/>
    <dbReference type="eggNOG" id="KOG4759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073981_2_0_1"/>
    <dbReference type="OMA" id="PNNDQQL"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032544">
        <property type="term" value="P:plastid translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.20:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="8">
        <location>
            <begin position="13"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="176" mass="19516" checksum="448E9C34BAF2582F" modified="2007-05-15" version="1">MERMEKTMDAIANDFSTVRTGRANAAVLDRIEVDYYGAPTPLKTIANASTPDAQTITIQPFDKSAIKDIERAINESDLGMNPSNDGNIIRLNVPPLTAERRKELAKLVSKLGEDGKVALRNVRRDAMKAYEKLEKAGSFGEDEIAKLKKSMEDLTASYVKKVDELTKAKETELQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTH9</accession>
    <name>A4RTH9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416073.1">
        <property type="nucleotide sequence ID" value="XM_001416036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTH9"/>
    <dbReference type="STRING" id="436017.A4RTH9"/>
    <dbReference type="GeneID" id="5000148"/>
    <dbReference type="Gramene" id="ABO94365">
        <property type="protein sequence ID" value="ABO94365"/>
        <property type="gene ID" value="OSTLU_29874"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29874"/>
    <dbReference type="HOGENOM" id="CLU_267104_0_0_1"/>
    <dbReference type="OrthoDB" id="10268124at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052798">
        <property type="entry name" value="Giardia_VSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23275">
        <property type="entry name" value="CABRIOLET.-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23275:SF100">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1237" mass="129081" checksum="AD78E4C455B2F75A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTK3</accession>
    <name>A4RTK3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_3605</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416055.1">
        <property type="nucleotide sequence ID" value="XM_001416018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTK3"/>
    <dbReference type="STRING" id="436017.A4RTK3"/>
    <dbReference type="GeneID" id="5000386"/>
    <dbReference type="Gramene" id="ABO94347">
        <property type="protein sequence ID" value="ABO94347"/>
        <property type="gene ID" value="OSTLU_3605"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3605"/>
    <dbReference type="eggNOG" id="KOG2757">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026967_2_1_1"/>
    <dbReference type="OMA" id="DIGLFCG"/>
    <dbReference type="OrthoDB" id="6605218at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07011">
        <property type="entry name" value="cupin_PMI_type_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018050">
        <property type="entry name" value="Pmannose_isomerase-type1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046458">
        <property type="entry name" value="PMI_typeI_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF0">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20512">
        <property type="entry name" value="PMI_typeI_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00965">
        <property type="entry name" value="PMI_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00966">
        <property type="entry name" value="PMI_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="10">
        <location>
            <begin position="3"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I helical insertion" evidence="11">
        <location>
            <begin position="184"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="407" mass="44049" checksum="CA2D45084CC87541" modified="2007-05-15" version="1" fragment="single">MRELRVKHQNYAWGARGSSAVRALALANAQRHDDARPEDFDDSTPFAELWCGTHASGMSDVVGEDGARTPLIEHVKSAANATLGERAVARFGDDVPFLMKMLSVARALSVQAHPDKALAVKLHESNPEAYKDDNHKPEMALCVSETFEAMSGFANADAVLTATRRHEEFGRVIGDDDAIEALRKAVESGQSNESAALRDAFKRVFTALMTAEKGKVETELRAMEARVRDEGTTATSSSSVESLFLRLCEQYPGDVGAFCAFVLNYVTLRPGEAIYMAANEPHAYLSGDCVEVMATSDNVVRAGLTPKFRDVQVLCDMLTYKLGAPEILTGDVVDACTRRYVPPFDEFLLDVVTVSRGTAYGVVAKSGPSVWIVHRGSCAFASAKDSKTFAAEPGAVFFVDADEECGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU24</accession>
    <name>A4RU24_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_7355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416596.1">
        <property type="nucleotide sequence ID" value="XM_001416559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU24"/>
    <dbReference type="GeneID" id="5001121"/>
    <dbReference type="KEGG" id="olu:OSTLU_7355"/>
    <dbReference type="eggNOG" id="ENOG502S21S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061685_0_0_1"/>
    <dbReference type="OMA" id="KFCEYTG"/>
    <dbReference type="OrthoDB" id="40334at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630:SF3">
        <property type="entry name" value="PEROXIREDOXIN-LIKE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="209" mass="22830" checksum="672B16DE558555A0" modified="2007-05-15" version="1" fragment="single">LFLTQFGDFDSWELAQRLVDDLDAMKRAGVRVVAIGIGSADAAREFSKRTRFPLENLYADEGGKCHEALGFAPGLGRAGGDFAWMEDKTPFVNGYAKLLLMCAGIGSPGTLPAVFGGYFGSKYKDEIFVEGSNLDVPAIRKAMKLTLGDGYLRPFELATLRLNNMIQILNNWEALTPKDSNLLVQRGGVIVFDDGKAAFRHDDQGILGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU34</accession>
    <name>A4RU34_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_30480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416889.1">
        <property type="nucleotide sequence ID" value="XM_001416852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU34"/>
    <dbReference type="STRING" id="436017.A4RU34"/>
    <dbReference type="GeneID" id="5001044"/>
    <dbReference type="Gramene" id="ABO95182">
        <property type="protein sequence ID" value="ABO95182"/>
        <property type="gene ID" value="OSTLU_30480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30480"/>
    <dbReference type="eggNOG" id="ENOG502QWFM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050695_0_0_1"/>
    <dbReference type="OMA" id="CHVNAGP"/>
    <dbReference type="OrthoDB" id="418407at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024521">
        <property type="entry name" value="ArsS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026351">
        <property type="entry name" value="rSAM_ArsS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04167">
        <property type="entry name" value="rSAM_SeCys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43728:SF1">
        <property type="entry name" value="FE-S OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43728">
        <property type="entry name" value="SLR0304 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12345">
        <property type="entry name" value="DUF3641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="64"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal" evidence="6">
        <location>
            <begin position="222"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="39524" checksum="CFFC55C6734DE5D7" modified="2007-05-15" version="1">MATDDEFQTAKTRLETLGQKALTKEERARRRRALDTIGVPSFESYLETRGGKALIREPTTILQVNIGLYCNQACAHCHVESSPLRTTEVMDAATAQAVVRVLKNSSNVKTLDLTGGAPELHEQFRFLVREARALGVDVIDRCNLTVLYEEGQEDLPQFLAENKVKVVASLPCYSEANTDAQRGKGVFERSIAALRDLNAVGYGVEGSGLELDLMYNPGGAFLPPAQENLEVAYRSELRDTWGVEFSRLFTLTNMPIKRFADYLHREGKTSEYMSLLVENFNVAASVGVMCRDLISVSWDGTLYDCDFNQQLDMPVRDEKKTIFDLDSCDDLVGSRIVADNHCFGCTAGSGSSCSGATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="116" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU70</accession>
    <name>A4RU70_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">phosphatidylinositol 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.137</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_34142</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.137" evidence="1"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416907.1">
        <property type="nucleotide sequence ID" value="XM_001416870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU70"/>
    <dbReference type="SMR" id="A4RU70"/>
    <dbReference type="STRING" id="436017.A4RU70"/>
    <dbReference type="GeneID" id="5001041"/>
    <dbReference type="Gramene" id="ABO95200">
        <property type="protein sequence ID" value="ABO95200"/>
        <property type="gene ID" value="OSTLU_34142"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34142"/>
    <dbReference type="eggNOG" id="KOG0906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004869_2_0_1"/>
    <dbReference type="OMA" id="LHKFAQY"/>
    <dbReference type="OrthoDB" id="67688at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:1-phosphatidylinositol-3-kinase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
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    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of defense response to bacterium"/>
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        <property type="project" value="EnsemblPlants"/>
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    <dbReference type="GO" id="GO:0072593">
        <property type="term" value="P:reactive oxygen species metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:regulation of L-proline metabolic process"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:regulation of stomatal closure"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:response to salicylic acid"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:response to salt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00896">
        <property type="entry name" value="PI3Kc_III"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol 3-kinase catalytic subunit type 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
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    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057756">
        <property type="entry name" value="PI3-kinase_type3/VPS34_cat"/>
    </dbReference>
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        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
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        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
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        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
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        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
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        <property type="entry name" value="PI3K_accessory_dom"/>
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        <property type="entry name" value="PI3K_accessory_sf"/>
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        <property type="entry name" value="PI3K_Vps34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF7">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
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    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PI3_4_KINASE_3"/>
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    </dbReference>
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        <property type="entry name" value="PIK_HELICAL"/>
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    </dbReference>
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    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="7">
        <location>
            <begin position="373"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="654" mass="74860" checksum="1E2DE40CC5420AB1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUB5</accession>
    <name>A4RUB5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416641.1">
        <property type="nucleotide sequence ID" value="XM_001416604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUB5"/>
    <dbReference type="GeneID" id="5000828"/>
    <dbReference type="Gramene" id="ABO94934">
        <property type="protein sequence ID" value="ABO94934"/>
        <property type="gene ID" value="OSTLU_14584"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14584"/>
    <dbReference type="HOGENOM" id="CLU_079738_0_0_1"/>
    <dbReference type="OMA" id="LQQASWC"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="276" mass="31134" checksum="796641DD20147251" modified="2007-05-15" version="1">MRRRRIRVAPSAGSRDDDDAGWDEGPIGGDEDDARWGGAPTKSREDDGDDWFGSMTSMDVDAYGDVMMGGKRSSGSTASSAADDIIDGANDWFNNNDDWFEPQYKEVNAPPGTMLEKVQRMTLNEPSDFSFKDGEYFDLMGYVKHKTDNEFCLVLEVAERARERKLERSESLSGTGPRLPPIQQAIADLALEIELSGGKTSAYLAMREAADRARLRYELQQASWCWDKYSEDSMRALGVSEKAEQMLHQGERIDEAMDFERELMIEDMNDSGTRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUC4</accession>
    <name>A4RUC4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GPR1/FUN34/yaaH family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_7849</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416936.1">
        <property type="nucleotide sequence ID" value="XM_001416899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUC4"/>
    <dbReference type="STRING" id="436017.A4RUC4"/>
    <dbReference type="GeneID" id="5000692"/>
    <dbReference type="Gramene" id="ABO95229">
        <property type="protein sequence ID" value="ABO95229"/>
        <property type="gene ID" value="OSTLU_7849"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7849"/>
    <dbReference type="eggNOG" id="ENOG502S8RE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051062_1_2_1"/>
    <dbReference type="OMA" id="IYLWAWF"/>
    <dbReference type="OrthoDB" id="505682at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015360">
        <property type="term" value="F:acetate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071422">
        <property type="term" value="P:succinate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047623">
        <property type="entry name" value="SatP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30178">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30178:SF3">
        <property type="entry name" value="SUCCINATE-ACETATE_PROTON SYMPORTER SATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="20012" checksum="F927A863E9957B44" modified="2007-05-15" version="1" fragment="single">MQTMTMKPPIANVGTLGLWAFALTTAMLSVKELRVGASDDGAVGVTIGFAFGFGGLVQLLAGILSALRGQSFSAVAFASYGGFWLSYGTYEVLAYEAVIPRDKVAEEAMLFMWGFLTLVLFCASLNTNVAISSLFFTLAALFFLLGGAKDSGSSALKLVASLFGVGVSIIAFYAGAGELINEQYGKTIIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUI0</accession>
    <name>A4RUI0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Threonylcarbamoyladenosine tRNA methylthiotransferase</fullName>
            <ecNumber evidence="4">2.8.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">tRNA-t(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_14633</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:37075"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="Rhea" id="RHEA-COMP:11092"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:74420"/>
            <dbReference type="EC" id="2.8.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylthiotransferase family. CDKAL1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.5" evidence="4"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416674.1">
        <property type="nucleotide sequence ID" value="XM_001416637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUI0"/>
    <dbReference type="STRING" id="436017.A4RUI0"/>
    <dbReference type="GeneID" id="5000778"/>
    <dbReference type="Gramene" id="ABO94967">
        <property type="protein sequence ID" value="ABO94967"/>
        <property type="gene ID" value="OSTLU_14633"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14633"/>
    <dbReference type="eggNOG" id="KOG4355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018697_4_1_1"/>
    <dbReference type="OMA" id="IASVLCH"/>
    <dbReference type="OrthoDB" id="1730074at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035598">
        <property type="term" value="F:tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12160:FF:000009">
        <property type="entry name" value="threonylcarbamoyladenosine tRNA methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000002">
        <property type="entry name" value="threonylcarbamoyladenosine tRNA methylthiotransferase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006466">
        <property type="entry name" value="MiaB-like_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01578">
        <property type="entry name" value="MiaB-like-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11918">
        <property type="entry name" value="RADICAL SAM PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11918:SF45">
        <property type="entry name" value="THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="17">
        <location>
            <begin position="38"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="167"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="16">
        <location>
            <begin position="400"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO94967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="516" mass="56307" checksum="5B3956AEBE9C26D4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV03</accession>
    <name>A4RV03_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PDEase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_34350</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416757.1">
        <property type="nucleotide sequence ID" value="XM_001416720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV03"/>
    <dbReference type="STRING" id="436017.A4RV03"/>
    <dbReference type="GeneID" id="5000569"/>
    <dbReference type="Gramene" id="ABO95050">
        <property type="protein sequence ID" value="ABO95050"/>
        <property type="gene ID" value="OSTLU_34350"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34350"/>
    <dbReference type="eggNOG" id="KOG3689">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005940_6_1_1"/>
    <dbReference type="OMA" id="RENCAYW"/>
    <dbReference type="OrthoDB" id="68317at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="71"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="401" mass="46007" checksum="576504400CFF6F83" modified="2007-05-15" version="1">MSDAGGPYLSVDGDALNSWSFDVFTVGENKELFPYVVRMFHEMNMFELVDQFKFRRFLSEVEGMYRDNPYHCFKHAVDVTHTTYLYICAVKEQVSMTQVEIFSLLVAALVHDLDHPGVTNGYLIATHDNIALTYNDESVLENLHLSRFFSLCQNNEDANILSAFDESTYKEIRRSIISCVLHTDMAHHFKLVSRLNELVALGKKNNIINGSPMKSTTDDERQLMLNVLLHCADISNAVKPNELCVKWASRVLEEFFNQGDRERSRGMSISPMMDRETTSVGLSQINFIEFVIAPLYVQFVAVFPALNGLLTRLIENRRYYQETYENELADMTKGDGTDRSPEKESLRARFRTLIEKHSLRRFVDESDNLMKAILSLPHTRRSSATRSFNAMLSSPSKKKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW00</accession>
    <name>A4RW00_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417239.1">
        <property type="nucleotide sequence ID" value="XM_001417202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW00"/>
    <dbReference type="STRING" id="436017.A4RW00"/>
    <dbReference type="GeneID" id="5001357"/>
    <dbReference type="Gramene" id="ABO95532">
        <property type="protein sequence ID" value="ABO95532"/>
        <property type="gene ID" value="OSTLU_31164"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31164"/>
    <dbReference type="HOGENOM" id="CLU_1221419_0_0_1"/>
    <dbReference type="OMA" id="DMPCLEC"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="227" mass="24870" checksum="4F32F31724DB0B34" modified="2007-05-15" version="1">MDDGDDGVVVVACAGAWHEDGRGACETPAEASERVFFGDRRQHVVFEGRDLDAMKIKARLDACLLTEAEDADETNRANESYCGSTWPTATEVMASAGVEAVERGVKHKAFYPSGGVDGVVASTAAMSVSTSRERGGDAFRDVRVPEAFAPPLAGQSEKTFPDGQVGYFFEDMPCLECGSPWWFGEDWDSRCANCGADDRTYGGDQRPIRSKRRIYDEFRAAWRRLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW86</accession>
    <name>A4RW86_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417283.1">
        <property type="nucleotide sequence ID" value="XM_001417246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW86"/>
    <dbReference type="GeneID" id="5001227"/>
    <dbReference type="Gramene" id="ABO95576">
        <property type="protein sequence ID" value="ABO95576"/>
        <property type="gene ID" value="OSTLU_92625"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92625"/>
    <dbReference type="HOGENOM" id="CLU_779354_0_0_1"/>
    <dbReference type="OrthoDB" id="10588184at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="356" mass="42348" checksum="52DC2BF83355D9EB" modified="2007-05-15" version="1">MPRPPGRPRKATHDVDLARDCWEFIFRRFLDSADPDVAVPSPPECEPPNANRLVEVLGGFLDDDEDERFWRNRHQHEERVRFWHNRRQHRKTTAKRVDFVRTQARTLLALPSVSKTFKEVCDEGGLFADMCDTLWARVKRLDDSLENGDKQAPPTMTSAQKLRLFEGTGCQSCDNHPLISFKWVFWGFGARLCQRCMRVRMVTEEVLQRDPDTLPEHYRGLPFSSDRYSAYGNPAPGRKLYWRADVDERKSVTRERQKRQREAEENEKKLLEKRKRKQFREEKLSQRDGVREQRKKDIIHMMTTTFDVTEAQLETSVSYRKHIAMARPLTARFHRTHMRQILDELPEECRRRRRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW92</accession>
    <name>A4RW92_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1-deoxy-D-xylulose-5-phosphate reductoisomerase</fullName>
            <ecNumber evidence="5">1.1.1.267</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">DXR</name>
        <name evidence="16" type="ORF">OSTLU_31255</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:13719"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DXR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="5"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417285.1">
        <property type="nucleotide sequence ID" value="XM_001417248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW92"/>
    <dbReference type="STRING" id="436017.A4RW92"/>
    <dbReference type="GeneID" id="5001481"/>
    <dbReference type="Gramene" id="ABO95578">
        <property type="protein sequence ID" value="ABO95578"/>
        <property type="gene ID" value="OSTLU_31255"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31255"/>
    <dbReference type="eggNOG" id="ENOG502QPJ7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035714_4_0_1"/>
    <dbReference type="OMA" id="AHPNWVM"/>
    <dbReference type="OrthoDB" id="3482at2759"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051484">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000183">
        <property type="entry name" value="1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009114">
        <property type="entry name" value="PRK12464.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525:SF0">
        <property type="entry name" value="1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal" evidence="13">
        <location>
            <begin position="62"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal" evidence="14">
        <location>
            <begin position="205"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="DXP reductoisomerase C-terminal" evidence="15">
        <location>
            <begin position="327"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO95578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="465" mass="50148" checksum="25E1F920625524AB" modified="2007-05-15" version="1">MTTATTATTKATARDARRETRARRAIATRASNNENRYGACWPGRAEVPANVAALGNGNVKKISLLGSTGSIGTQTLDICEEHPDKFEVVALSAGRNVTLVAEQCAKFSPKLVSVQNGEDVAKLRDALQKLGCAMPEIMYGEDGMVEVARHADCDSVVTGIVGCAGLPPTVAAIEAGKNICLANKETLIAGGPAIVPLAVKHGVKILPADSEHSALFQCIQGMPEGALRRIILTASGGAFRDMDLATMRELAVSDPAALHKKATTHPNWDMGAKITCDSATLMNKALEVIEAHYLYGTSYDNIDVIVHPQSIVHSMVETSDSSVLAQLGWPDMRLPILYTMSWPNRVECSEVTWPRLDFVKMGDLTFRAPDFEKYPSLTMGYAAGRAGGTMTGVFSAANEQAVAMFLDKKMGYFDIYKVIELAMEAHKNELVLDPSLDDIVHYDLWARDHVKQTVESGVLTGALPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWJ1</accession>
    <name>A4RWJ1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CaCA family transporter: sodium ion/calcium ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_87097</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/calcium exchanger (CCX) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417340.1">
        <property type="nucleotide sequence ID" value="XM_001417303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWJ1"/>
    <dbReference type="GeneID" id="5001424"/>
    <dbReference type="Gramene" id="ABO95633">
        <property type="protein sequence ID" value="ABO95633"/>
        <property type="gene ID" value="OSTLU_87097"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87097"/>
    <dbReference type="eggNOG" id="KOG2399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004979_1_2_1"/>
    <dbReference type="OMA" id="NPLCARD"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051359">
        <property type="entry name" value="CaCA_antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266:SF0">
        <property type="entry name" value="MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266">
        <property type="entry name" value="NA+/CA2+ K+ INDEPENDENT EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672941" evidence="11">
        <location>
            <begin position="29"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="431"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="570"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="94"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="437"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="603" mass="63784" checksum="88C368B0FC181EE2" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWM9</accession>
    <name>A4RWM9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417606.1">
        <property type="nucleotide sequence ID" value="XM_001417569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWM9"/>
    <dbReference type="GeneID" id="5001547"/>
    <dbReference type="Gramene" id="ABO95899">
        <property type="protein sequence ID" value="ABO95899"/>
        <property type="gene ID" value="OSTLU_31394"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31394"/>
    <dbReference type="eggNOG" id="ENOG502S2M6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_886794_0_0_1"/>
    <dbReference type="OMA" id="NQEWHAD"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35580" checksum="5B1A7145B8160DCA" modified="2007-05-15" version="1">MDVTIAWRCRACSSEDARLERRVRAWMATRGWDAEATTTMTAPGYVPLGSIDAVTKETLDWGRKDRTDEERVAAFADAGVATCLKAVDEETTREIREATERFVERVERRFEESFGDIVYGRDRFAFREIGSRGGERFDALVDLELEEWATLRALARDDAPWRALVDALMPNGWNVHVSVVYSRPGAKNQEWHADGRHLDVECDVRTGCGHAPPYGVCVFMPLIDLSRETGFTQFFMRSHKTSKLIGFGDASLILRLSFDGILDAGQSVAYDYRLLHRGMANDSLANRPVLQFLYTAPAYRETKNYGTRSLWSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWN4</accession>
    <name>A4RWN4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RuvB-like helicase</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RUVBL3501</name>
        <name evidence="10" type="ORF">OSTLU_31398</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RuvB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417360.1">
        <property type="nucleotide sequence ID" value="XM_001417323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWN4"/>
    <dbReference type="STRING" id="436017.A4RWN4"/>
    <dbReference type="GeneID" id="5001551"/>
    <dbReference type="Gramene" id="ABO95653">
        <property type="protein sequence ID" value="ABO95653"/>
        <property type="gene ID" value="OSTLU_31398"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31398"/>
    <dbReference type="eggNOG" id="KOG1942">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028311_1_1_1"/>
    <dbReference type="OMA" id="RTLPYNK"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048507">
        <property type="term" value="P:meristem development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900150">
        <property type="term" value="P:regulation of defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905323">
        <property type="term" value="P:telomerase holoenzyme complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="62"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="455" mass="49560" checksum="260ED46270BDC53E" modified="2007-05-15" version="1">MKIDEVPSLAKKSRVAAHTHIKGLGLKESGEAAETAAGWIGQENAREACGLCADMIREKKMAGRALLMTGAPGTGKTALALGISQELGTRVPFCPMVGSEVYSSEIKKTEVLMENFRRAIGLRIKEVKEVYEGEVVEMTPEETESTSGGYGKVISHVVVGLKSVKGTKQLKLDPAIYEALQQEKVQTGDVIYIEANSGSVKRVGRCDAYATEFDLEAEEYVPLPKGDVHKRKEIVQDVTLHDLDAANAKPVGGHDIVAVMNQLSKGKKTEITEKLRHEINKVVNGYIDQGIAELVPGVLFIDEVHMLDIECFAYLNKALESSLAPIVILATNRGICTVKGTDIQAPHGIPTDLLDRLMIVRTMTYTVEEMVRILAVRAQVEGLDIDEESLAHLADVGDRTSLRHAMQLLSPAFVVAKTNGREKVVLADLQECEDLFIDAKASAKLLSEQADKYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="109" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWZ8</accession>
    <name>A4RWZ8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_31513</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417909.1">
        <property type="nucleotide sequence ID" value="XM_001417872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWZ8"/>
    <dbReference type="STRING" id="436017.A4RWZ8"/>
    <dbReference type="GeneID" id="5001761"/>
    <dbReference type="Gramene" id="ABO96202">
        <property type="protein sequence ID" value="ABO96202"/>
        <property type="gene ID" value="OSTLU_31513"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31513"/>
    <dbReference type="eggNOG" id="KOG0050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009082_0_0_1"/>
    <dbReference type="OMA" id="EAQYLCA"/>
    <dbReference type="OrthoDB" id="496424at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
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        <location>
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        </location>
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        </source>
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    <sequence length="756" mass="84216" checksum="B2309481C1DE7967" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX57</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">OSTLU_31576</name>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="189" mass="20420" checksum="710F25D5EC15F13B" modified="2007-05-15" version="1">MFTLTTSTVLARPAVRARAHARRATPIVRANAPTANAANFAPTQRQQTREVAQIAGKAPPPPPPARIITSAQYVTAFSAVMGVYALQMLLVPAKMITDHFNASADQLTQFWIRGSSVAFAGLVYAVQQLDVATGAKIALFASFAVGVLYPWNAKWNLLKNNLSVKYPMHYVPEALMALLSLAGAYCVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX95</accession>
    <name>A4RX95_OSTLU</name>
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        <recommendedName>
            <fullName evidence="6">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_5358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4RX95"/>
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    <dbReference type="Gramene" id="ABO96251">
        <property type="protein sequence ID" value="ABO96251"/>
        <property type="gene ID" value="OSTLU_5358"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="10256793at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:unfolded protein binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chaperone protein dnaJ 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DnaJ_C"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="294" mass="31745" checksum="674A80E4B29D5262" modified="2007-05-15" version="1" fragment="single">RSYYEVLGVERGASAGEIKKAYYALAKKYHPDTNKGDEETEKRFQEVQKAYEVLRDAKTRSAYDQVGHANYESMENGGGGAGGGGFSGFQDFGGRGGFQGFYQSGGGAGGFDPFEEVLQDFFGGGRGGARDIQANVQITLDDVRRGVSREINIPETVTNVDIPKGVEDGQRLRVAGEGIRGVGGRVGSLYINVQVRMDPRFRRVGSDLVTSIDIPFPTAALGGTVKAPTMDGEVEVKVRKATQHGDQLRLRGRGLPVLGTALVGDLFVRFSVSTPANLSPRQEELLKEFAEEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXS2</accession>
    <name>A4RXS2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418044.1">
        <property type="nucleotide sequence ID" value="XM_001418007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXS2"/>
    <dbReference type="GeneID" id="5001777"/>
    <dbReference type="Gramene" id="ABO96337">
        <property type="protein sequence ID" value="ABO96337"/>
        <property type="gene ID" value="OSTLU_31794"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31794"/>
    <dbReference type="eggNOG" id="ENOG502QUHX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_347601_0_0_1"/>
    <dbReference type="OMA" id="THYNCET"/>
    <dbReference type="OrthoDB" id="413408at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="VSR Endonuclease"/>
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    </dbReference>
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        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="683"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="753" mass="84520" checksum="C62E29D5860331F3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXY7</accession>
    <name>A4RXY7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="5001788"/>
    <dbReference type="Gramene" id="ABO96371">
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        <property type="gene ID" value="OSTLU_15541"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15541"/>
    <dbReference type="eggNOG" id="KOG3621">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_278906_0_0_1"/>
    <dbReference type="OMA" id="RKLWIAK"/>
    <dbReference type="OrthoDB" id="19493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23287">
        <property type="entry name" value="RUBY-EYE2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23287:SF16">
        <property type="entry name" value="TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="823"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1118" mass="120629" checksum="B46ADADFC4A700D5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY94</accession>
    <name>A4RY94_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC(ABCG) family transporter: multidrug</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_1450</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY94"/>
    <dbReference type="GeneID" id="5002290"/>
    <dbReference type="Gramene" id="ABO96640">
        <property type="protein sequence ID" value="ABO96640"/>
        <property type="gene ID" value="OSTLU_1450"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1450"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_57_6_1"/>
    <dbReference type="OMA" id="MERAMFY"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF91">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="AlphaFoldDB" id="A4RYK2"/>
    <dbReference type="STRING" id="436017.A4RYK2"/>
    <dbReference type="GeneID" id="5002472"/>
    <dbReference type="Gramene" id="ABO96471">
        <property type="protein sequence ID" value="ABO96471"/>
        <property type="gene ID" value="OSTLU_15693"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15693"/>
    <dbReference type="HOGENOM" id="CLU_1196566_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="232" mass="24598" checksum="0E6D818B9E604F51" modified="2007-05-15" version="1">MTIVHRPAANNNGVASKATTGSSKASNGVHRTHGGVHKMSQVSSRASAQTNVSVDHSAHYHHNAANGSALTASLSNLADMAAREAHYVASIPQHQSTSTSTSQAIKIDEESHRSFPMMTAAYPGHFAAPMAATQAPVFDAYNQAMAQYMLQLQSLAAQQGDGMSHINQINQMNQMAWMAQQNLAYQMAAQNYAATPLSPQQNANFCRPTAIYAAKSIDDNVGEQRNAASGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ27</accession>
    <name>A4RZ27_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Adenosine deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_5107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine</text>
            <dbReference type="Rhea" id="RHEA:16001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:59338"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:16002"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418502.1">
        <property type="nucleotide sequence ID" value="XM_001418465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ27"/>
    <dbReference type="STRING" id="436017.A4RZ27"/>
    <dbReference type="GeneID" id="5002276"/>
    <dbReference type="Gramene" id="ABO96795">
        <property type="protein sequence ID" value="ABO96795"/>
        <property type="gene ID" value="OSTLU_5107"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5107"/>
    <dbReference type="eggNOG" id="KOG1097">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039228_3_0_1"/>
    <dbReference type="OMA" id="RPQFKPY"/>
    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF42">
        <property type="entry name" value="ADENOSINE DEAMINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="311" mass="34343" checksum="C81302925F43EA4B" modified="2007-05-15" version="1" fragment="single">VELHAHVNGCVREDTLLELAAARGLERECERALASDRDLLACFEIFKLVHACVDDAAALRRVTREVCEDFARDGARYLELRTTPKEQIGKERYVEAVLSGLEDACGRCGGDGADGELAARIILSVDRARDDDASKAMETIDLAIKYKERGVVGVDLSGSPVVGHWDRYVAAFEKARAHGLGTSLHNGEVANTEAEQRAFIAFRPDRLGHCVYTVRDESLLRDLLASKIPVELCLTSNVKTRSCAGFAEHHFAKLRSAGHPICLCTDDTWVFQTSLSREYAIAAETFGLTDDEIRDMSTRAMDFAFCDEDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ67</accession>
    <name>A4RZ67_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyanobacterial aminoacyl-tRNA synthetase CAAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418523.1">
        <property type="nucleotide sequence ID" value="XM_001418486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ67"/>
    <dbReference type="GeneID" id="5002486"/>
    <dbReference type="Gramene" id="ABO96816">
        <property type="protein sequence ID" value="ABO96816"/>
        <property type="gene ID" value="OSTLU_24709"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24709"/>
    <dbReference type="HOGENOM" id="CLU_856318_0_0_1"/>
    <dbReference type="OrthoDB" id="498917at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="34842" checksum="D3FB6E91ED16BC50" modified="2007-05-15" version="1">MTTTTTTTRSMGIIGRARATDALARRPRATRERVARRAGGVMTSAVFNFGGPAAEERKAAVRGYMDAGSGTQKKKKPTFVLPKKVAAKPKPKAKPKPKAKPKPKVVAKKPVATKKPLFAAKAKPLVKKPVAAKKPSFAAKKPIAAKKPIAAKKPIAAKKPIAAKKPIVRRKPMVASKPKPKPFARKPAQRPVRRSASSKSLKETADLGFYAIIAGSFLLSVAILPGIADVALETIGIAYTLYFTYNYLAFEESREKFKNTLENIESGTGIDIPSIFDSTIESAIVEPAPSLPQEGSGTDASRRSYPHFSSCRDETASINAHNLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZA3</accession>
    <name>A4RZA3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_2670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418295.1">
        <property type="nucleotide sequence ID" value="XM_001418258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZA3"/>
    <dbReference type="STRING" id="436017.A4RZA3"/>
    <dbReference type="GeneID" id="5002507"/>
    <dbReference type="Gramene" id="ABO96588">
        <property type="protein sequence ID" value="ABO96588"/>
        <property type="gene ID" value="OSTLU_2670"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2670"/>
    <dbReference type="eggNOG" id="KOG2769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015750_2_0_1"/>
    <dbReference type="OMA" id="CVMHPRF"/>
    <dbReference type="OrthoDB" id="10264544at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24162">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013881">
        <property type="entry name" value="Pre-mRNA_splic_Prp3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027104">
        <property type="entry name" value="Prp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212">
        <property type="entry name" value="U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08572">
        <property type="entry name" value="PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 3" evidence="6">
        <location>
            <begin position="66"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="5">
        <location>
            <begin position="328"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="452" mass="51862" checksum="D705A783E4A763AA" modified="2007-05-15" version="1" fragment="single">RPSARPMALRLDAQGREIDERGELVVNKVIETSTLSVNLKQQRANAFAQAQAEAQAEIASQAGADFDDPRMRAFAGKTRKKRSALQFVEDGKFQKEADMHRLRMQFGDEKAERMKERSERERKHAERMEKLEKEATMDPNLVPVGERPSAAKGASAARPLAPLDEIPDVEWWDRDILRNGTYDDVTGGKWNVNMDKFNVYVEHPVPIKPPLNAPAPAPQPLMLTKAEQKKLRTQRRVAREKEKQEMIRQGLIEPPKPKVKISNLMRVLKDEAVLDPTAMEKEVREQMAEREQAHQDRNLARMLTPAERREKKMRKLLGNDAAGEVHMHVYRVEDMSNTKNKFKVDVNAQENHLTGVGLIAEAFTIVIVEGTAKAVRRYDKLMMRRIDWNAKLNDDNDEMDADDAKKNKCTRVWRGTSTSHALRRFCFETFRSDAAARRYLAEFKLEHLYDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZH4</accession>
    <name>A4RZH4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="3">2.5.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_3723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the IPP transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="3"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418572.1">
        <property type="nucleotide sequence ID" value="XM_001418535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZH4"/>
    <dbReference type="STRING" id="436017.A4RZH4"/>
    <dbReference type="GeneID" id="5002608"/>
    <dbReference type="Gramene" id="ABO96865">
        <property type="protein sequence ID" value="ABO96865"/>
        <property type="gene ID" value="OSTLU_3723"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3723"/>
    <dbReference type="eggNOG" id="KOG1384">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032616_0_2_1"/>
    <dbReference type="OMA" id="HEECCHI"/>
    <dbReference type="OrthoDB" id="775260at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088:SF60">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01715">
        <property type="entry name" value="IPPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="38797" checksum="D7958B98825CEDDC" modified="2007-05-15" version="1" fragment="single">TRRAKVLVVTGPTAIGKSAVAIAMARARRERRDAREVEIVSCDSVQIYRGLDVGSGKVGARELEACAHHMLSALDPRARDGSGEYDANAYYDEAVNVIDDIHRRGRDAVVVGGAGMYLKWLTDGKPSAPGSTPETREAAERAVGEARARGGWREAVELLTRAGDAETGKTLSENDWYRLTRAYEIVRTSGQSVKAFARENPEARFDFRCFFLSSPRVELYRKIDARVEGMFVDGIMDEAAWLLNAGIAPGENVPARSIGYRQAMEYLAKARAKEIKVDDASLLELVNEIQMLNRAYAKRQFTWFRGESRYAWINVDDDRDAVARRILSEFDRDEHRAGGEEIGDLSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZQ5</accession>
    <name>A4RZQ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_2246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418611.1">
        <property type="nucleotide sequence ID" value="XM_001418574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZQ5"/>
    <dbReference type="GeneID" id="5003024"/>
    <dbReference type="Gramene" id="ABO96904">
        <property type="protein sequence ID" value="ABO96904"/>
        <property type="gene ID" value="OSTLU_2246"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2246"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_2_0_1"/>
    <dbReference type="OMA" id="ESDISTM"/>
    <dbReference type="OrthoDB" id="496945at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF28">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="299" mass="32922" checksum="28140EE74BCD2293" modified="2007-05-15" version="1" fragment="single">HDRNAKRLHAMCGANGGLYVKAGQFASTAGGVPEAYARRLSKLQDEVAPSPRDAVLKVVRNEFGGRAPEALFETFEPEPMAAASLAQVHRAVLKSGRTVAVKIQRPGLERSIESDISTMSALVRFTRLFFPSFDFGFMVDEFKSRLEKEIDFEAEGRNCERLGLAFADDARIDTPEVFWDLTTRRVLTMEFIDGEKLTNIEGMREKGLDPEHAALALSDCFARMLLVHGYIHGDPHPGNLLCRAHPDGSGRTQVVLLDHGLYSELTEESRKAMSNLWIAIAVGDSVRAVAAAKALQVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZY4</accession>
    <name>A4RZY4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418649.1">
        <property type="nucleotide sequence ID" value="XM_001418612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZY4"/>
    <dbReference type="GeneID" id="5002861"/>
    <dbReference type="Gramene" id="ABO96942">
        <property type="protein sequence ID" value="ABO96942"/>
        <property type="gene ID" value="OSTLU_32555"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32555"/>
    <dbReference type="HOGENOM" id="CLU_892521_0_0_1"/>
    <dbReference type="OMA" id="MKAWISE"/>
    <dbReference type="OrthoDB" id="498832at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="33686" checksum="5F79632A32821E55" modified="2007-05-15" version="1">MRARSCRATTSRTRGRTARARAATTNGDAQNVAFDAAAIGRWAARAREAPWDARGAGWREFFAAKPIGAVVEVDNARETISAKEVESHGLNWPTCRAEAVERARVNTVRFRQNYAQIACAATLLGSECAAFAMALVSFYAYLALRSDRILGELSLATKDALKWNDAVVAGVSRSKLKSTTLGVAVVLFLLSDATANTYAIMRSVAWTAAIALLHAILRPIDLKGTLADIVKDFRAAKSKEDLRGAARSGLKSMKAWISEKAKPVEATPIFVVEKGEKKRSDGADATPARRSEDANGAIDVDAREAEDTKYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S077</accession>
    <name>A4S077_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cilia- and flagella-associated protein 52</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_35708</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the CFAP52 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418927.1">
        <property type="nucleotide sequence ID" value="XM_001418890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S077"/>
    <dbReference type="STRING" id="436017.A4S077"/>
    <dbReference type="GeneID" id="5002978"/>
    <dbReference type="Gramene" id="ABO97220">
        <property type="protein sequence ID" value="ABO97220"/>
        <property type="gene ID" value="OSTLU_35708"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35708"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009244_2_0_1"/>
    <dbReference type="OMA" id="RIMVYNF"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF14">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="439"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="484"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="611"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="678" mass="72816" checksum="13CCDD4AD536FCA5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S082</accession>
    <name>A4S082_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418697.1">
        <property type="nucleotide sequence ID" value="XM_001418660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S082"/>
    <dbReference type="STRING" id="436017.A4S082"/>
    <dbReference type="GeneID" id="5002683"/>
    <dbReference type="Gramene" id="ABO96990">
        <property type="protein sequence ID" value="ABO96990"/>
        <property type="gene ID" value="OSTLU_32648"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32648"/>
    <dbReference type="eggNOG" id="KOG2936">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1573271_0_0_1"/>
    <dbReference type="OMA" id="NGWHWEE"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF21">
        <property type="entry name" value="ACTIVATOR OF HSP90 ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="2">
        <location>
            <begin position="29"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="170" mass="19236" checksum="6EDF0EE86AC99A54" modified="2007-05-15" version="1">MAKWGEGDSRWIVDERRDGTNINGWHWEERNMMKWSRERIESLLVGVDLDVPVSEGRATVTELSKFEGDSSVSTRKGGKKFGCFDLSFTAKWRGVVGVAADSTEDEDEVKGEIVVKEFCSTNDEDEYDFAVSAKDGKSESKALLKSRVEKSVEAILLPKLRQFCEELKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S091</accession>
    <name>A4S091_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
            <ecNumber evidence="2">1.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_35630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.193" evidence="2"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418702.1">
        <property type="nucleotide sequence ID" value="XM_001418665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S091"/>
    <dbReference type="STRING" id="436017.A4S091"/>
    <dbReference type="GeneID" id="5002688"/>
    <dbReference type="Gramene" id="ABO96995">
        <property type="protein sequence ID" value="ABO96995"/>
        <property type="gene ID" value="OSTLU_35630"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35630"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_1_1_1"/>
    <dbReference type="OMA" id="APHFKFN"/>
    <dbReference type="OrthoDB" id="206452at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00402"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046443">
        <property type="term" value="P:FAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009644">
        <property type="term" value="P:response to high light intensity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050765">
        <property type="entry name" value="Riboflavin_Biosynth_HTPR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011:SF7">
        <property type="entry name" value="2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="6">
        <location>
            <begin position="218"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="45662" checksum="AFA71EE838B9ADB7" modified="2007-05-15" version="1" fragment="single">MSAASPSRALARARAASASSTAPSSSTESPPASRRPRARPRRARAATLRAVTPRDAEIMTRVCELARAREGIAAPHPLSACAVTRGDGDVVVEATHAGQGSTRAEIACADEMRRRGATLNSSDRGTVYVNLEPAHGEVAGETRSVEALAATGATRAVVGMLHPLPGLRGRAVRALRERGIEVCVLEGEAEGFEGEAARACRETNEALLYRVATGLPFSVYKYAMTLDGKIATDTGHSSWVTGAEAREMVFRERKRADAVVVGGGTVRKDNPRLTCREETGFQPARVVLTRSLDLPEDAKLWNVRGVAPTIVCTTKGVKPEFQNALRAKGVEVVEFDELTPLAAAQYMFKRGFLRCFWECGGGLAAPAMKSGVFHEVLAFIAPKLVGGGALAPTPLGNLGIEAMHDALPLSGVRLEIYGRDILIRGYVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0B4</accession>
    <name>A4S0B4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418941.1">
        <property type="nucleotide sequence ID" value="XM_001418904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0B4"/>
    <dbReference type="GeneID" id="5003035"/>
    <dbReference type="Gramene" id="ABO97234">
        <property type="protein sequence ID" value="ABO97234"/>
        <property type="gene ID" value="OSTLU_93036"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93036"/>
    <dbReference type="HOGENOM" id="CLU_971111_0_0_1"/>
    <dbReference type="OrthoDB" id="10534301at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="287" mass="30986" checksum="0E658914F22EB7B5" modified="2007-05-15" version="1">MFARVSAPARPRTTPQASRRALSTRCAPRTPSAPRADLKPRPRQENDCFQIAATSTRALAPPAQFTPAQVFAFKCGLVLGLPLALYKIALDVRAQNIAERRRAAALGAKTRAASALDGRRDGMLRADAVAAKREARSEMRRRTNVMDIPVASNKKREVVMPTRAMAKPATKPTAAVESKATARAPKAKGPPVKITLATQCALPDGVGLAVVGDDSAIERPIAMQRVGADRYQIVLEVGSGNLTYMYVAKKGDKLIKENRVKEGKGERTRQIDLDGKPLVIETEAPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0J6</accession>
    <name>A4S0J6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418988.1">
        <property type="nucleotide sequence ID" value="XM_001418951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0J6"/>
    <dbReference type="GeneID" id="5002778"/>
    <dbReference type="Gramene" id="ABO97281">
        <property type="protein sequence ID" value="ABO97281"/>
        <property type="gene ID" value="OSTLU_93059"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93059"/>
    <dbReference type="HOGENOM" id="CLU_1047295_0_0_1"/>
    <dbReference type="OrthoDB" id="421328at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="266" mass="29966" checksum="2326B1A422F4E1F3" modified="2007-05-15" version="1">MAHDADDGDVVRLNALLSKWREPKMQRVLPRLVIPDATNRANSGVSLEHAHGIAMSICEDGFNENHDVPVVVRERARDMLKSDAYRRWEAFSRANARVLPEVSARTWASRRWAYATLGSSHLNLALKLIEYDVPSVFERRWERSRRIRYGDALTRDAGLREAIVNGLPSVVLRSETPPEARREISLMLNRAEDVGFRINERGEAVRVRDGGDEIKELTVFEALSRTLDSEELSSLARIKYGLDLDDAEAGYVADAAANTASLRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0S9</accession>
    <name>A4S0S9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_16296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418793.1">
        <property type="nucleotide sequence ID" value="XM_001418756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0S9"/>
    <dbReference type="GeneID" id="5002853"/>
    <dbReference type="Gramene" id="ABO97086">
        <property type="protein sequence ID" value="ABO97086"/>
        <property type="gene ID" value="OSTLU_16296"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16296"/>
    <dbReference type="HOGENOM" id="CLU_1671681_0_0_1"/>
    <dbReference type="OMA" id="FDPICEF"/>
    <dbReference type="OrthoDB" id="10556834at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="172" mass="17164" checksum="ED88638F70727362" modified="2007-05-15" version="1">MIVDVPRDARAKTRAWAVVIVAFVFASSAAAGVRASESGVGGAPSARRSLVDVTGAAFFDVFGFELSASAAFDPICEFLNPFLHPDYRLSACAEEQAAAAEYEDEYEAYGEGRDRIVMDPEGTFVNGVTGNVAGGIGGGGIGGVAGGSAGFIGGGLGGVGGGVGAGPIGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0V1</accession>
    <name>A4S0V1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_32875</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419252.1">
        <property type="nucleotide sequence ID" value="XM_001419215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0V1"/>
    <dbReference type="STRING" id="436017.A4S0V1"/>
    <dbReference type="GeneID" id="5003458"/>
    <dbReference type="Gramene" id="ABO97545">
        <property type="protein sequence ID" value="ABO97545"/>
        <property type="gene ID" value="OSTLU_32875"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32875"/>
    <dbReference type="eggNOG" id="KOG1494">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047181_0_2_1"/>
    <dbReference type="OMA" id="EACAEYC"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="12">
        <location>
            <begin position="59"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="13">
        <location>
            <begin position="203"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="63"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="173"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="370" mass="38236" checksum="85C76885CD9F156B" modified="2007-05-15" version="1">MSNAVGAAARRVGALRAQVVDPASSSRQTPQEAPSARVGLVDWFFGASGIGGKRASFTVAVLGAAGGIGQTLSAFIKANPKVAELRLYDVAPVVRGVAADVSHVNTRAKVSGYVGDDELEACLRGCDLVIIPAGVPRKPGMSRDDLFGVNAGIVRTLCEGVAKTCPNAIVNIISNPVNSTVPIAAEVFKNHGCYDARKLLGVTHLDVMRAKTFVAAAKGFDDPTLVDVPVIGGHAGTTILPLLSQTTPRCSFTPEEVSALTSRIQNGGTEVVEAKGGAGSATLSMAAAAAEFADACLRGLSGESGIWACAYVESKATRAPFFATKVLLGRNGVERVAGTGTLSSYEKRALESMLPELEASIKKGINFLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S125</accession>
    <name>A4S125_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_50201</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419289.1">
        <property type="nucleotide sequence ID" value="XM_001419252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S125"/>
    <dbReference type="STRING" id="436017.A4S125"/>
    <dbReference type="GeneID" id="5003343"/>
    <dbReference type="Gramene" id="ABO97582">
        <property type="protein sequence ID" value="ABO97582"/>
        <property type="gene ID" value="OSTLU_50201"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50201"/>
    <dbReference type="eggNOG" id="ENOG502QQ6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002399_1_0_1"/>
    <dbReference type="OMA" id="SFHVRNY"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056301">
        <property type="entry name" value="GWD-like_N_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054481">
        <property type="entry name" value="GWD1_pHisD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46999:SF1">
        <property type="entry name" value="ALPHA-GLUCAN WATER DIKINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46999">
        <property type="entry name" value="ALPHA-GLUCAN WATER DIKINASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22973">
        <property type="entry name" value="GWD1_pHisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23166">
        <property type="entry name" value="Ig_N_CWD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-glucan water dikinase-like N-terminal Ig-like" evidence="13">
        <location>
            <begin position="13"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glucan water dikinase phosphohistidine-like" evidence="12">
        <location>
            <begin position="572"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="11">
        <location>
            <begin position="839"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1043" mass="115065" checksum="8B3B9FDED29E0A80" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1E5</accession>
    <name>A4S1E5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_33071</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419351.1">
        <property type="nucleotide sequence ID" value="XM_001419314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1E5"/>
    <dbReference type="STRING" id="436017.A4S1E5"/>
    <dbReference type="GeneID" id="5003097"/>
    <dbReference type="Gramene" id="ABO97644">
        <property type="protein sequence ID" value="ABO97644"/>
        <property type="gene ID" value="OSTLU_33071"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33071"/>
    <dbReference type="eggNOG" id="KOG1550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023963_0_0_1"/>
    <dbReference type="OMA" id="HWRAPYE"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671844" evidence="3">
        <location>
            <begin position="33"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="689"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="711" mass="78060" checksum="E576A743609CF82D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1G3</accession>
    <name>A4S1G3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Succinate dehydrogenase [ubiquinone] cytochrome b small subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_33089</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CybS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419361.1">
        <property type="nucleotide sequence ID" value="XM_001419324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1G3"/>
    <dbReference type="STRING" id="436017.A4S1G3"/>
    <dbReference type="GeneID" id="5003466"/>
    <dbReference type="Gramene" id="ABO97654">
        <property type="protein sequence ID" value="ABO97654"/>
        <property type="gene ID" value="OSTLU_33089"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33089"/>
    <dbReference type="eggNOG" id="ENOG502S9AK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2269020_0_0_1"/>
    <dbReference type="OMA" id="TIWRESP"/>
    <dbReference type="OrthoDB" id="18577at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007992">
        <property type="entry name" value="CybS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13337">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13337:SF2">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05328">
        <property type="entry name" value="CybS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <note>ligand shared with SDHC</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <note>ligand shared with IP/SDHB</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR607992-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR607992-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="108" mass="11073" checksum="B584F66FF61A9422" modified="2007-05-15" version="1">MSGVLNADRGRGMMKIYHASSIALAALAPAAAAMPEGQLAIDVALGAAMPVHSHIAMNFIISDYVPKGARGPTRAATLALTAATAVGLFKLNTQGDGITRTVKSLWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1J6</accession>
    <name>A4S1J6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_5662</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419159.1">
        <property type="nucleotide sequence ID" value="XM_001419122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1J6"/>
    <dbReference type="SMR" id="A4S1J6"/>
    <dbReference type="STRING" id="436017.A4S1J6"/>
    <dbReference type="GeneID" id="5003217"/>
    <dbReference type="Gramene" id="ABO97452">
        <property type="protein sequence ID" value="ABO97452"/>
        <property type="gene ID" value="OSTLU_5662"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5662"/>
    <dbReference type="eggNOG" id="KOG2937">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008108_1_0_1"/>
    <dbReference type="OMA" id="KLNMSAI"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="86"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="234"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="34973" checksum="E8CE3D38968100EF" modified="2007-05-15" version="1" fragment="single">EIYLELAARFVLNAPPSEIEDFNRLMFLIEQAHWYYIDFTCEQDASLSASMGLNEFAKGMISSVETLKSRIPGFKNNFEKFKSYKFAIPTCGAVLLNPTMDKCLMVRGWGSQNKSLGFPKGKMDANETEAECAAREVEEEIGVDIRQFIVEEDKVVFMRKRKPSDKLGQKNTLYLIQGISEETKFLTHTRKEISDIVWNPLWIFDQPEEALKKFKNKYGQIYPALRDIMAWVKQNKKKHPKPRTNQVAAPQSPAAGRAAPMSLEDLENELMSGYDDEPEDDEPAKPHKAFEALTNFKFNKARILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1R1</accession>
    <name>A4S1R1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_1537</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419411.1">
        <property type="nucleotide sequence ID" value="XM_001419374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1R1"/>
    <dbReference type="STRING" id="436017.A4S1R1"/>
    <dbReference type="GeneID" id="5003168"/>
    <dbReference type="Gramene" id="ABO97704">
        <property type="protein sequence ID" value="ABO97704"/>
        <property type="gene ID" value="OSTLU_1537"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1537"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="ARYVGTI"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="16">
        <location>
            <begin position="32"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="63"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="263"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="32"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO97704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="394" mass="42972" checksum="D1B6837724E8B76A" modified="2007-05-15" version="1" fragment="single">ALTEAQTTEIRERLGVTVEIEEGEAAVPSAIESFEDMTLVRDIMADIRYREYDKPSPIQAQAIPVILSGRDVLGCAETGSGKTAAFSIPMIQHALNQAPLRQGDGPYAIVMAPTRELAQQIEAEAKTFTRSSKGFRTAIIVGGTNMSEQRGALRSGVQIVVATPGRLIDHLQQGNTNLSRVSFVVLDEADRMLDMGFEPQIREVLMNLPKPHQTLLFSATMPSEVEALASDYLHKPVKVKVGTTSAPTANVSQHLEKVVDAEKVDRLVTMLIGEQREAMKLGQDMPMTVIFVERKNRADEIAELLNAENVPAAALHGGRSQGEREAALHDYKTGRCSVLVATDVAARGLDVKGVAHVVNLDLPRNFEDYVHRIGRTGRAGMSGRSTSFYTDRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S270</accession>
    <name>A4S270_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419481.1">
        <property type="nucleotide sequence ID" value="XM_001419444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S270"/>
    <dbReference type="GeneID" id="5003635"/>
    <dbReference type="Gramene" id="ABO97774">
        <property type="protein sequence ID" value="ABO97774"/>
        <property type="gene ID" value="OSTLU_33346"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33346"/>
    <dbReference type="HOGENOM" id="CLU_1104266_0_0_1"/>
    <dbReference type="OMA" id="TMTARME"/>
    <dbReference type="OrthoDB" id="441129at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14845">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING 166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14845:SF0">
        <property type="entry name" value="DUF4515 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="252" mass="28967" checksum="B9E5CA24ECED8DF0" modified="2007-05-15" version="1">MGNKREGEARARAEVEARARAEAEAKALAAERGALTERERALRAFVEDKKAHDEALRRAREECARLTVALESERADMERAFAARTGAMRAECDARVAKAKKQAESTMTARMERSVKRILAQNRKMSDELRVQVNETDALHRRFAKANAEAESLRRRAAAADDVERERAELGAMRARDLRRAEEKITTLERGIRELMEAFETQKLEWERETNDLRRANDEEVTHLKRSLALKSRELVNIRRLAKEVVCHYEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2B5</accession>
    <name>A4S2B5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419723.1">
        <property type="nucleotide sequence ID" value="XM_001419686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2B5"/>
    <dbReference type="STRING" id="436017.A4S2B5"/>
    <dbReference type="GeneID" id="5003724"/>
    <dbReference type="Gramene" id="ABO98016">
        <property type="protein sequence ID" value="ABO98016"/>
        <property type="gene ID" value="OSTLU_25015"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25015"/>
    <dbReference type="HOGENOM" id="CLU_700943_0_0_1"/>
    <dbReference type="OrthoDB" id="10500399at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="394" mass="41115" checksum="A75934AD30B67C77" modified="2007-05-15" version="1">MEDAPLLTRDGDGDRRHRSSRARASTSVFRPTFALGVTLACACALAKTNGVGRTIARDWMSGDDARERASANERGKMSAFGSAAALATSGDGTTPFAVVSDPFVTGGGDDDGASEEYSLVRKSQMSSSGDIEVNHREDVEMIPRAAATMVHLTLLTACAQLGSLTFAPGAWEDVVGARVTTKSMSNDFLFSQAQEMTQTRCGTFEVDVMLGAGEQFGFYLYPLDNTSDEATVSDIGCLHRGGGRCPKFATPSALEGMEVCTSVIEEGDDIFYNRVFDGKTFTYVYGSCDEGCALKAPSGCPASHMPEVTTLDTGVCTDPAHAGIYNALCAQSCGAGTTDCDASCRAASDAGVSLSCVPGARGADACRCAHVAANATTECTVPGYDCCTCESIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2G8</accession>
    <name>A4S2G8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">HAM3502</name>
        <name evidence="15" type="ORF">OSTLU_34656</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419529.1">
        <property type="nucleotide sequence ID" value="XM_001419492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2G8"/>
    <dbReference type="STRING" id="436017.A4S2G8"/>
    <dbReference type="GeneID" id="5003645"/>
    <dbReference type="Gramene" id="ABO97822">
        <property type="protein sequence ID" value="ABO97822"/>
        <property type="gene ID" value="OSTLU_34656"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34656"/>
    <dbReference type="eggNOG" id="KOG2747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011815_2_1_1"/>
    <dbReference type="OMA" id="CWKTGVA"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000022">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000002">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF219">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="14">
        <location>
            <begin position="129"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="13">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="48446" checksum="BDAC8BD7D90D0788" modified="2007-05-15" version="1">MARDDAGRRKSESTSDRAGALDVGARVWAKASFDEKRRLGEIVDVRREDGVAVAYYVHYSELNKRLDAWVPVEDVETRKEGEGEVNGKQPKTLTRNSKRRYNEIHNVDAPVEDLPPMDQMFERMHEEKTKVKNVHSIELGRHEMDTWYYSPYPDDFGKCSKLYLCQYCFKYMRKAKTCVRHKAECEMKHPPGKRVYRHPQGEGEPLLSFWEIDGAHFKMYCQNLCLMAKLFLDHKTLYFDVEPFMFYVLTESMDGDETHDIVGYFSKEKVSVDDYNLACILTLPAYQRKGYGSFLISMSYELSRRQGVYGTPERPLSDLGQVSYRSYWSRVVLDVLHKHRGNLSVKDLSSMLMFREADIVSALQSLNLVKYWKGQHIISSSPKIVEEHLSSFEKKSAIAGTRLEFNPEYLNWTAPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2N2</accession>
    <name>A4S2N2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">O-acyltransferase WSD1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419779.1">
        <property type="nucleotide sequence ID" value="XM_001419742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2N2"/>
    <dbReference type="STRING" id="436017.A4S2N2"/>
    <dbReference type="GeneID" id="5003618"/>
    <dbReference type="Gramene" id="ABO98072">
        <property type="protein sequence ID" value="ABO98072"/>
        <property type="gene ID" value="OSTLU_94705"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94705"/>
    <dbReference type="eggNOG" id="ENOG502S2TJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_812388_0_0_1"/>
    <dbReference type="OMA" id="TEPILLM"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045034">
        <property type="entry name" value="O-acyltransferase_WSD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009721">
        <property type="entry name" value="O-acyltransferase_WSD1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650">
        <property type="entry name" value="O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650:SF1">
        <property type="entry name" value="WAX ESTER SYNTHASE_DIACYLGLYCEROL ACYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06974">
        <property type="entry name" value="WS_DGAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="O-acyltransferase WSD1 C-terminal" evidence="2">
        <location>
            <begin position="202"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="345" mass="37603" checksum="C6F4B537FBA19CE5" modified="2007-05-15" version="1">MNEATLKPFDAESPLWDCVVVTRKKTSAAWDGDAKTSPEPPVVMFRVSHAIGDGIALVDVLKKVSTALDGGDMRLLDFKRRAAKAHKSVLAVIWAFITFIFVCIYGALKAVFTAAGPYDTKTTFKGSRKRRVVVCPPIPMEDVKKIKNGSGCTVNDIVVAALAGAIQQYLEEMGDKSAAKKPLIRAATPYAFPNRVVGALTNSWTFVSLTFPMGVMSAAERLSKAQKVCNFMKRSPEPYVTRALNEVVATAGPDVQRQVVFDYMSRHSMVFTNVPGPTEPILLMGSRVRDIVFACSNLVNQVSVFSYAGNLRLTLVVDPDATPDADYIGEAFAREIQTLRANVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2N9</accession>
    <name>A4S2N9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419565.1">
        <property type="nucleotide sequence ID" value="XM_001419528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2N9"/>
    <dbReference type="GeneID" id="5003564"/>
    <dbReference type="Gramene" id="ABO97858">
        <property type="protein sequence ID" value="ABO97858"/>
        <property type="gene ID" value="OSTLU_16788"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16788"/>
    <dbReference type="HOGENOM" id="CLU_1858621_0_0_1"/>
    <dbReference type="OrthoDB" id="10604782at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="138" mass="14848" checksum="50250458EADD7682" modified="2007-05-15" version="1">MVAGELDAELAALADEAQAARERNARVKKEIEELAEELLGSGQRVNNDSKPAPGSLSELKMKAVEAEADAVDKRMQATLQDTQRATTYTMVLLLLSFLGFTLVAEGAYDKFAAVAGAFALVAYQSRAELQAKSKGKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Z5</accession>
    <name>A4S2Z5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7 9">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_16869</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7 9"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419623.1">
        <property type="nucleotide sequence ID" value="XM_001419586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Z5"/>
    <dbReference type="STRING" id="436017.A4S2Z5"/>
    <dbReference type="GeneID" id="5003890"/>
    <dbReference type="Gramene" id="ABO97916">
        <property type="protein sequence ID" value="ABO97916"/>
        <property type="gene ID" value="OSTLU_16869"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16869"/>
    <dbReference type="eggNOG" id="KOG1253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010862_0_0_1"/>
    <dbReference type="OMA" id="PNPTPYW"/>
    <dbReference type="OrthoDB" id="495709at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160104">
        <property type="term" value="F:tRNA (guanine(26)-N2)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002940">
        <property type="term" value="P:tRNA N2-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.70:FF:000001">
        <property type="entry name" value="tRNA (guanine(26)-N(2))-dimethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="378"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="427" mass="47546" checksum="9E7316865C912600" modified="2007-05-15" version="1">MSATGLRALRYAQELENVGCVVANDMDPTAAEAIERNKAYNALCSPDKAEAISRVIPHNEDVRMVCMKHEKMFDVVDLDPYGTPSTLLDSAVTSVKEGGLLLVTATDMAVLCGNNAEVAWAKYQSYPLRAKYCHEMAVRTLLAAVENAAIKHRRHIVPVISLSIDFYIRVFVRVYTSPLQMKQTPSKLSYVFQCVGCDAHELQAVGRQQTKGNVTKYQPGVGPVVPQRCSSCGWHYNMGGPIWSDPIHDKTWVTNVKSELERNKDAYPGYGKVHALLTMASEELLDVPLHYDLHAMGGTLKATPPSFWLFKSAVMNAGYRVSGSHSNPLAIKTDAPVDVLWDILRCWVKEHPVKPQSSPTPGEAILAKEPTVIANWTRRTEAQSKAQKDGVARFPQNPTADWGPKRRAGKYREEELEAKRRKEEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S356</accession>
    <name>A4S356_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_9067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419859.1">
        <property type="nucleotide sequence ID" value="XM_001419822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S356"/>
    <dbReference type="STRING" id="436017.A4S356"/>
    <dbReference type="GeneID" id="5003864"/>
    <dbReference type="Gramene" id="ABO98152">
        <property type="protein sequence ID" value="ABO98152"/>
        <property type="gene ID" value="OSTLU_9067"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9067"/>
    <dbReference type="eggNOG" id="KOG1729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2079116_0_0_1"/>
    <dbReference type="OMA" id="WDEIFHM"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000286">
        <property type="entry name" value="PH-protein kinase domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336:SF8">
        <property type="entry name" value="PROTEIN OPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="7"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="118" mass="13549" checksum="D0AB91FF2A878CEF" modified="2007-05-15" version="1" fragment="single">GIRFWETPEYSGWLTKQGEMLRTWRKRWFVLKQGHLVWFKTNVVNERAVTRGEIPIESIDSVSVASEAAAGKPYAIHLEGALPARIGTKYLVADSERERSQWLEALQKAMRERTSTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S374</accession>
    <name>A4S374_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lhca2</name>
        <name evidence="8" type="ORF">OSTLU_33699</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419664.1">
        <property type="nucleotide sequence ID" value="XM_001419627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S374"/>
    <dbReference type="STRING" id="436017.A4S374"/>
    <dbReference type="GeneID" id="5003874"/>
    <dbReference type="Gramene" id="ABO97957">
        <property type="protein sequence ID" value="ABO97957"/>
        <property type="gene ID" value="OSTLU_33699"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33699"/>
    <dbReference type="eggNOG" id="ENOG502QRXM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057943_6_0_1"/>
    <dbReference type="OMA" id="QHARWAM"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="25710" checksum="E79E227AB0358C67" modified="2007-05-15" version="1">MSVSMRISSTAGLKTRVATKTRASRGPVAVSANADRPVWYPGKAPAAHLDGSLPGDYGFDPLSLSADPEMRQWMVQAELQHARWAMLGVAGCVAPELLTKIGVADLPNWVDAATYQYWAPGGTLFFIQMAMFNWAEIRRWQDMKNPGSVNTDPLFGYNSNDTNTDVGYPKGLFDKFGWAKDEKTTAELKLKEIKNGRLAMLAFLGICAQYVQTGVGPVENLFSHMGNPGQVGVFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3H0</accession>
    <name>A4S3H0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar proton pump subunit B</fullName>
            <shortName evidence="6">V-ATPase subunit B</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Vacuolar proton pump subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_88387</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420095.1">
        <property type="nucleotide sequence ID" value="XM_001420058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3H0"/>
    <dbReference type="STRING" id="436017.A4S3H0"/>
    <dbReference type="GeneID" id="5004049"/>
    <dbReference type="Gramene" id="ABO98388">
        <property type="protein sequence ID" value="ABO98388"/>
        <property type="gene ID" value="OSTLU_88387"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88387"/>
    <dbReference type="eggNOG" id="KOG1351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022916_3_0_1"/>
    <dbReference type="OMA" id="EGFKIKP"/>
    <dbReference type="OrthoDB" id="1735853at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051693">
        <property type="term" value="P:actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18112">
        <property type="entry name" value="ATP-synt_V_A-type_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18118">
        <property type="entry name" value="ATP-synt_V_A-type_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01135">
        <property type="entry name" value="V_A-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12240:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit B, brain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005723">
        <property type="entry name" value="ATPase_V1-cplx_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003235">
        <property type="entry name" value="PRK04196.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01040">
        <property type="entry name" value="V-ATPase_V1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389:SF4">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="8">
        <location>
            <begin position="40"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="7">
        <location>
            <begin position="161"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="9">
        <location>
            <begin position="403"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="505" mass="55659" checksum="7C26EF302C26DCE5" modified="2007-05-15" version="1">MSPADALASDFARTQIAAAKATIDAIDAIDPKLTYRTVRAVAGPLVILDQVSNAKYAEIVNVKLGDGTLRRGQVLEVDGERAVVQIFEGTSGIDGKRTELEFTGEVLKTPVSEDMLGRIFNGSGNPIDGGPPVMAEKYLDIQGASINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRRDDEGREVEGGDAGTSAGEDDFAIVFAAMGVNLETANFFRRDFERTGSLEKVVLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIKGRKGSITQLPILTMPNDDITHPIPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHGEVSNQLYANYAIGKDTLAMKAVVGEEALSSDDLLYLEFLDKFERKFINQGNEGRNIYDALDLAWSLLRIFPRELLKRIPAKTLDRYYDRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3J6</accession>
    <name>A4S3J6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_8483</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419930.1">
        <property type="nucleotide sequence ID" value="XM_001419893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3J6"/>
    <dbReference type="STRING" id="436017.A4S3J6"/>
    <dbReference type="GeneID" id="5004061"/>
    <dbReference type="Gramene" id="ABO98223">
        <property type="protein sequence ID" value="ABO98223"/>
        <property type="gene ID" value="OSTLU_8483"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8483"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_4_3_1"/>
    <dbReference type="OMA" id="VKGFMMQ"/>
    <dbReference type="OrthoDB" id="407558at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000025">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CYP19-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="17241" checksum="867E940A572DFBDB" modified="2007-05-15" version="1" fragment="single">RVVFELFDAKSARACENFRALCEGMGTSRATGRRRTYEGSRMHRCVRNFMMQGGDYTHGNGAGGESIWGKKFKDDAGGLKLKHDAMGVLSMSNTGKNSNSSQFFVTLGACKHLDGKHVVFGKCVRGMDVLERINDECAVDAGGTSEEPKVPVVVAGCGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3T3</accession>
    <name>A4S3T3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase metallophosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419975.1">
        <property type="nucleotide sequence ID" value="XM_001419938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3T3"/>
    <dbReference type="STRING" id="436017.A4S3T3"/>
    <dbReference type="GeneID" id="5004158"/>
    <dbReference type="Gramene" id="ABO98268">
        <property type="protein sequence ID" value="ABO98268"/>
        <property type="gene ID" value="OSTLU_26163"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26163"/>
    <dbReference type="eggNOG" id="ENOG502QTGZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041740_0_0_1"/>
    <dbReference type="OMA" id="EHGFETW"/>
    <dbReference type="OrthoDB" id="10266805at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987:SF1">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="433" mass="49437" checksum="DB680934F4493E70" modified="2007-05-15" version="1">MRRPDARTTSLRIGFGSCNKQSLDMTLLWPDVAREEYDAFAWIGDAVYADERVKLANGERTRRYLGEKAHEEAYERVKRDEAYAAVRRRADVVGTWDDHDYGFNNAGKHWSRKAFAKKAFLDFLDEPVGSERRTREGGVWDSVDYVDEASGRRARVILLDLRWDLEEPDEVSEGKMMSETQWAWFETQLAAEPKPEVTIVGSGIQVIEAPHLMLRPLAPYVEPARLVAEGLESWSRVPREQSRLFDTIKRTGARVVFMSGDVHHGQIAAAAPGCYLPYKTIDITSSGFTHTPFRDAKPWPLALFLRLATPKYFRQWILPSYTRWTDINYGEIEIDWARGAVFARIKSVGGKVALEESVTFAELDENVPDLGFDRAGCNLTLEMSPKMRAFRIVVFFTWLAGVYAFKFLAPIFVAAYAVRKARRYARARGLKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3T4</accession>
    <name>A4S3T4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_6391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420149.1">
        <property type="nucleotide sequence ID" value="XM_001420112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3T4"/>
    <dbReference type="STRING" id="436017.A4S3T4"/>
    <dbReference type="GeneID" id="5004015"/>
    <dbReference type="Gramene" id="ABO98442">
        <property type="protein sequence ID" value="ABO98442"/>
        <property type="gene ID" value="OSTLU_6391"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6391"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_2_1"/>
    <dbReference type="OMA" id="WWSSVAN"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051935">
        <property type="entry name" value="HSDL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42808">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42808:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="263" mass="28054" checksum="951D31677AC7BAC4" modified="2007-05-15" version="1" fragment="single">LAGKVAVVSGASRGIGRACALALARRGVNVVVAAKSATESATLPGTVHGVARECDAVATHGARAMGCVVNLLDEASILACVARAKARYGRIDVLVNNASALWWQDIEDTPTKKYDLIQGVNARGAFVLTRACLREMRAGGRGGRVISMGPPLPKSYKEYETKTAYYMSKCGMSMVALGAAAEGEKYGVTGNALWPATIVESLASENFELGSRDNWRKADILADCVVELCCDAHTTGQTLIDDEYLQTRGAKFPEDFVKYRCNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3X8</accession>
    <name>A4S3X8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419961.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S3X8"/>
    <dbReference type="GeneID" id="5003956"/>
    <dbReference type="Gramene" id="ABO98291">
        <property type="protein sequence ID" value="ABO98291"/>
        <property type="gene ID" value="OSTLU_26208"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26208"/>
    <dbReference type="HOGENOM" id="CLU_842924_0_0_1"/>
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        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:cilium-dependent cell motility"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003352">
        <property type="term" value="P:regulation of cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039750">
        <property type="entry name" value="DRC1/DRC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21625">
        <property type="entry name" value="NYD-SP28 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="37552" checksum="4689489D67E8FFBA" modified="2007-05-15" version="1">MDESERTHRVEAEAQARRLEEASTRADAETATIDARATGRLRALRETFESEDARADERWREDVQEALERAEAGRTAFEREQDARRASFEDKREEIRNQHGEDVSTMKIMYENKIKELESELARVTAPSVTKGELGCADNHWDAEEELDHERAYELIRARDDADAKRLANTKRQIQKLQSKVDHWREKTHSRTSEWNASHARRVAERDQLLRRYDDVKSGVTAMRDARASALRKMCVSSEHAIKELTRTLEHARRVLRVESLNADLRRRHGVDVEASTHSPRRSSRDAASDAIADYHFSDAPMDYAQSVLERFYARRTAQSSPRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S428</accession>
    <name>A4S428_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CHR3517</name>
        <name evidence="5" type="ORF">OSTLU_26262</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ABO98315"/>
        <property type="gene ID" value="OSTLU_26262"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26262"/>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF5">
        <property type="entry name" value="SNF2 DOMAIN-CONTAINING PROTEIN _ HELICASE DOMAIN-CONTAINING PROTEIN _ HNH ENDONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="206"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="528"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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        </source>
    </evidence>
    <sequence length="1148" mass="126084" checksum="615CCBB18C776584" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S435</accession>
    <name>A4S435_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93380</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420199.1">
        <property type="nucleotide sequence ID" value="XM_001420162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S435"/>
    <dbReference type="GeneID" id="5004176"/>
    <dbReference type="Gramene" id="ABO98492">
        <property type="protein sequence ID" value="ABO98492"/>
        <property type="gene ID" value="OSTLU_93380"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93380"/>
    <dbReference type="eggNOG" id="ENOG502S5DJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_667912_0_0_1"/>
    <dbReference type="OMA" id="FSVVWYV"/>
    <dbReference type="OrthoDB" id="415691at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="466" mass="51408" checksum="2BF42ABE3893F894" modified="2007-05-15" version="1">MASCATCGTAFASRNALFRHLRRDGPCRAIDDADDASTSSMGARAGVHKTSVARAFDARARGEDGPTLAYASSGRSHKKERDMTKEEVRALNERRRKRAAIRKELRARGGDSSGTAAGDPAADLWLGGLSGSAGTMKGVRQVIWHAMPHNSDLPQPQVKFIKRRGYKVNGEWKAFAFLQCRDADEARVLQAAMNEVSVTLKDGVTSVLKARPAAYKNKTNDAKAAPAAVAPPARALPPGEHPPAREIFMAWTAKDLEQRALARGMTHAALIDEAVASNEAASYVNLRGVAVDSAATQRLKDELLRSKWPARSHRRGVKSDGYIVLKRELSPNDPYAKLKDACERLMRTVDETFPYDSLAITKNFISSAHLDKDDKSHQYSMSFGTFTGGGELCVESKDGKTRWMIDTRERLARFDGRSVHWVRGYSGDRFSVVWYVNRESYFTPQRYDVDETFVGVDSSSSRCVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4B8</accession>
    <name>A4S4B8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein phosphatase inhibitor 2 (IPP-2)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420243.1">
        <property type="nucleotide sequence ID" value="XM_001420206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4B8"/>
    <dbReference type="GeneID" id="5004309"/>
    <dbReference type="Gramene" id="ABO98536">
        <property type="protein sequence ID" value="ABO98536"/>
        <property type="gene ID" value="OSTLU_26354"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26354"/>
    <dbReference type="HOGENOM" id="CLU_1621739_0_0_1"/>
    <dbReference type="OMA" id="QCKGRAT"/>
    <dbReference type="OrthoDB" id="10538116at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04979">
        <property type="entry name" value="IPP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18599" checksum="3368F18AAC4CA982" modified="2007-05-15" version="1">MTPRRDDAASPKRAKRAVEWDEANLAKNFAERSATMKIEEIETPWHSPPRELFHDLRAEDEGEVARRERAHEEVMRRLEALIRADARGETSTPPTTKDADATMGDEGSEDGTSRVAFHDPDARDEDFEDDAEEVVKKRLFDAKRKAFQCKGRATARFLADEAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4F0</accession>
    <name>A4S4F0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">BRCA2 OB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_26389</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420425.1">
        <property type="nucleotide sequence ID" value="XM_001420388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4F0"/>
    <dbReference type="STRING" id="436017.A4S4F0"/>
    <dbReference type="GeneID" id="5004323"/>
    <dbReference type="Gramene" id="ABO98718">
        <property type="protein sequence ID" value="ABO98718"/>
        <property type="gene ID" value="OSTLU_26389"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26389"/>
    <dbReference type="eggNOG" id="KOG4751">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_290257_0_0_1"/>
    <dbReference type="OMA" id="IASEMEW"/>
    <dbReference type="OrthoDB" id="21095at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04493">
        <property type="entry name" value="BRCA2DBD_OB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015525">
        <property type="entry name" value="BRCA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015252">
        <property type="entry name" value="BRCA2_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036315">
        <property type="entry name" value="BRCA2_hlx_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015187">
        <property type="entry name" value="BRCA2_OB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002093">
        <property type="entry name" value="BRCA2_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11289:SF0">
        <property type="entry name" value="BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11289">
        <property type="entry name" value="BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09169">
        <property type="entry name" value="BRCA-2_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09103">
        <property type="entry name" value="BRCA-2_OB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81872">
        <property type="entry name" value="BRCA2 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50138">
        <property type="entry name" value="BRCA2_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Breast cancer type 2 susceptibility protein helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="BRCA2 OB1" evidence="7">
        <location>
            <begin position="473"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="18"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="269"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="992"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1055" mass="114919" checksum="1FC1639C42030D7C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4F9</accession>
    <name>A4S4F9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DMT family transporter: UDP-galactose/UDP-glucose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_43912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420259.1">
        <property type="nucleotide sequence ID" value="XM_001420222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4F9"/>
    <dbReference type="GeneID" id="5004327"/>
    <dbReference type="Gramene" id="ABO98552">
        <property type="protein sequence ID" value="ABO98552"/>
        <property type="gene ID" value="OSTLU_43912"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43912"/>
    <dbReference type="eggNOG" id="KOG1581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036019_3_0_1"/>
    <dbReference type="OMA" id="VAFANWA"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF13">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="390" mass="42984" checksum="B5FA5E388DA84C9B" modified="2007-05-15" version="1">MSRRAVDAARDDRVVSCDDDVDSRSLASDPSRASTSHAATTDFAVLLHPTAHFILVAAATIGSLALYGVLQERVMTIPYARERGESEDVFTCSMFLVFMNRWVALASSGALAMVTGWGGGATRGGAKDYAAVSFSNLVATVCQYEVLKYLTYSVSTLAKTMKVVPVMIWGQFLGEKKFTSREYFDAAVMTFGCFVFVANRGWRSAVQKRYEGEYDESSLEWAANAGFLILAVYFVFDGFTSTFQQKMYRRDGVTVTAQVFFTSFFTTVFGFAWLVITDQLSPSIRFVHDHPAIVGDILLLSCASTVAQFSIAYTIKSYSAVILASIMTFRQFLSVLISCYVFSSPLNVVQWLGILLILAPLTFKHVAFANWAESAHPSSSKSDDDRLNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4R7</accession>
    <name>A4S4R7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_17346</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420481.1">
        <property type="nucleotide sequence ID" value="XM_001420444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4R7"/>
    <dbReference type="STRING" id="436017.A4S4R7"/>
    <dbReference type="GeneID" id="5004560"/>
    <dbReference type="Gramene" id="ABO98774">
        <property type="protein sequence ID" value="ABO98774"/>
        <property type="gene ID" value="OSTLU_17346"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17346"/>
    <dbReference type="eggNOG" id="KOG1434">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041732_0_0_1"/>
    <dbReference type="OMA" id="ANPMKPV"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002052">
        <property type="entry name" value="DNA repair protein RAD51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF30">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="5">
        <location>
            <begin position="118"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="6">
        <location>
            <begin position="295"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="38496" checksum="D954FC2928E38EFE" modified="2007-05-15" version="1">MSTTAARRKKSAAAAAEETMVDVEEDAGVTFAEEQSNIVSIDALQQSGVSATDIKKLRDAGFVTVRQLLMFPRKAIIAVKGFSDAKADKVLEGAVKLLPESEAGGFVTAAEDAERRKDVVHITSGAAAVDAILGGGFESRAITEIYGEWRCGKTQLCHTIAVTTQMPVEMGGGCAKVAWIDTENTFRGDRLVQIANRFGLDADAVLSNVMVARVDTVDQMMHALIAIGAKMAEEPFKLLVVDSIMAIFRVDYVARGELSERQQTLNQFLSRLRKIAEEFNVAVVLTNQVQSDPGGMAFAGVEPKKAIGGHVLAHASTIRLMVRKGRAEARVLKVLQGPTLKEDEAEFQITEGGVTGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4W1</accession>
    <name>A4S4W1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26548</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420336.1">
        <property type="nucleotide sequence ID" value="XM_001420299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4W1"/>
    <dbReference type="STRING" id="436017.A4S4W1"/>
    <dbReference type="GeneID" id="5004515"/>
    <dbReference type="Gramene" id="ABO98629">
        <property type="protein sequence ID" value="ABO98629"/>
        <property type="gene ID" value="OSTLU_26548"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26548"/>
    <dbReference type="eggNOG" id="KOG2265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1752777_0_0_1"/>
    <dbReference type="OMA" id="ATSRECE"/>
    <dbReference type="OrthoDB" id="416217at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="11"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="149" mass="16266" checksum="566288D4F0212B35" modified="2007-05-15" version="1">MVSLTKEQCGGTTARYAWTQSEDEIVVSFAAPADATSRECEVTLTSTAATVRVRGQTLLDGELTRAIVKDDSYWELESDGSQKVLRLSLTKLRRTCAKFHWPSVCVGEPEIDVAAFGDPVMGVTGNLNGDAMKTMMEDVAAMRRDAEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S507</accession>
    <name>A4S507_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_1511</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="8">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420359.1">
        <property type="nucleotide sequence ID" value="XM_001420322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S507"/>
    <dbReference type="STRING" id="436017.A4S507"/>
    <dbReference type="GeneID" id="5004415"/>
    <dbReference type="Gramene" id="ABO98652">
        <property type="protein sequence ID" value="ABO98652"/>
        <property type="gene ID" value="OSTLU_1511"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1511"/>
    <dbReference type="eggNOG" id="KOG0348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_2_1"/>
    <dbReference type="OMA" id="IHEQICE"/>
    <dbReference type="OrthoDB" id="422663at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17949">
        <property type="entry name" value="DEADc_DDX31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="32"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="262"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="560" mass="60880" checksum="D1AABF555FFC39E2" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5U3</accession>
    <name>A4S5U3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26883</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420671.1">
        <property type="nucleotide sequence ID" value="XM_001420634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5U3"/>
    <dbReference type="STRING" id="436017.A4S5U3"/>
    <dbReference type="GeneID" id="5004690"/>
    <dbReference type="Gramene" id="ABO98964">
        <property type="protein sequence ID" value="ABO98964"/>
        <property type="gene ID" value="OSTLU_26883"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26883"/>
    <dbReference type="eggNOG" id="KOG4685">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_724414_0_0_1"/>
    <dbReference type="OMA" id="CCEDAYY"/>
    <dbReference type="OrthoDB" id="10249562at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="5">
        <location>
            <begin position="245"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="382" mass="43097" checksum="7CC231B5B929BA97" modified="2007-05-15" version="1">MFPTSVRKPSPGPAPDASESDERAASPAPSEPSARTSDDERVERDYDEGAAESAREKYRLQGKAGCDRVLEALRREKESVKETRQYLFGRLLNLQLEEAVLRDHLNATWKRGKRRAALKHKRPEQLVESLIREFGVVRGTRARGQVWIGATRRLGYLLEQTCLGRRARAGTEIGVPLTPNGAGNELVIRVCCEDAYYMCAFLRCLVVSEDGDEDAAREIRLGLGTREMDCETLWRVFRRDCGHAFALKCAATVHFRLTGWLPRSGLQYGADFVLYQRHPSLVHSDSTVVLVPDAAARRSFQIDDDDAPHRGVALDNGWPDWPDLQATSRLAVQVSKKFIEAHISAPKNVNWNEPSCLQHIYVNEIEVSRFNTKKHLENYQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6G1</accession>
    <name>A4S6G1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7148 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420937.1">
        <property type="nucleotide sequence ID" value="XM_001420900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6G1"/>
    <dbReference type="STRING" id="436017.A4S6G1"/>
    <dbReference type="GeneID" id="5005046"/>
    <dbReference type="Gramene" id="ABO99230">
        <property type="protein sequence ID" value="ABO99230"/>
        <property type="gene ID" value="OSTLU_17819"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17819"/>
    <dbReference type="eggNOG" id="ENOG502RZTF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1597223_0_0_1"/>
    <dbReference type="OMA" id="LYQWANG"/>
    <dbReference type="OrthoDB" id="1930092at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055572">
        <property type="entry name" value="DUF7148"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36352">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36352:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23650">
        <property type="entry name" value="DUF7148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7148" evidence="1">
        <location>
            <begin position="45"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="167" mass="17368" checksum="C41A006EBAF572BA" modified="2007-05-15" version="1">MSLAMTTRARSAPVVGVDARRRRGANADVKARARCVARASEANDDDDGIQLGTAKLPPTCDETALCDALYQWASTLTSSGQNLPFALSQRVDRTNDGFELAFLTAAKNGAPGELAAVGAIAASVEVAGQEKVLMIRGYGNVMNLVDTPVVMGAMPAAIRRAVAMSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6K4</accession>
    <name>A4S6K4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_27152</name>
        <name evidence="13" type="ORF">OSTLU_36629</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420960.1">
        <property type="nucleotide sequence ID" value="XM_001420923.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422934.1">
        <property type="nucleotide sequence ID" value="XM_001422897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6K4"/>
    <dbReference type="SMR" id="A4S6K4"/>
    <dbReference type="STRING" id="436017.A4S6K4"/>
    <dbReference type="GeneID" id="5005166"/>
    <dbReference type="GeneID" id="5006992"/>
    <dbReference type="Gramene" id="ABO99253">
        <property type="protein sequence ID" value="ABO99253"/>
        <property type="gene ID" value="OSTLU_27152"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01293">
        <property type="protein sequence ID" value="ABP01293"/>
        <property type="gene ID" value="OSTLU_36629"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27152"/>
    <dbReference type="KEGG" id="olu:OSTLU_36629"/>
    <dbReference type="eggNOG" id="KOG2198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_4_3_1"/>
    <dbReference type="OMA" id="QLFTEYV"/>
    <dbReference type="OrthoDB" id="6093671at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016428">
        <property type="term" value="F:tRNA (cytidine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000271">
        <property type="entry name" value="NOL1/NOP2/Sun family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057285">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057286">
        <property type="entry name" value="PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023270">
        <property type="entry name" value="RCMT_NCL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25376">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25378">
        <property type="entry name" value="PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02011">
        <property type="entry name" value="RCMTNCL1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="11">
        <location>
            <begin position="42"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP01293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="700" mass="78889" checksum="5426C53ADF89DDAD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6V9</accession>
    <name>A4S6V9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_36544</name>
        <name evidence="2" type="ORF">OSTLU_41554</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421161.1">
        <property type="nucleotide sequence ID" value="XM_001421124.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422794.1">
        <property type="nucleotide sequence ID" value="XM_001422757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6V9"/>
    <dbReference type="STRING" id="436017.A4S6V9"/>
    <dbReference type="GeneID" id="5005219"/>
    <dbReference type="GeneID" id="5006942"/>
    <dbReference type="Gramene" id="ABO99454">
        <property type="protein sequence ID" value="ABO99454"/>
        <property type="gene ID" value="OSTLU_41554"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01153">
        <property type="protein sequence ID" value="ABP01153"/>
        <property type="gene ID" value="OSTLU_36544"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36544"/>
    <dbReference type="KEGG" id="olu:OSTLU_41554"/>
    <dbReference type="eggNOG" id="KOG1243">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010392_1_0_1"/>
    <dbReference type="OMA" id="EGPPWAI"/>
    <dbReference type="OrthoDB" id="447103at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="613" mass="68192" checksum="6A4EC4990BD66BAB" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S723</accession>
    <name>A4S723_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_5256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421198.1">
        <property type="nucleotide sequence ID" value="XM_001421161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S723"/>
    <dbReference type="STRING" id="436017.A4S723"/>
    <dbReference type="GeneID" id="5005527"/>
    <dbReference type="Gramene" id="ABO99491">
        <property type="protein sequence ID" value="ABO99491"/>
        <property type="gene ID" value="OSTLU_5256"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5256"/>
    <dbReference type="eggNOG" id="KOG2961">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056221_3_1_1"/>
    <dbReference type="OMA" id="PDCQQCV"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006655">
        <property type="term" value="P:phosphatidylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048364">
        <property type="term" value="P:root development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010021">
        <property type="entry name" value="PGPP1/Gep4"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01668">
        <property type="entry name" value="YqeG_hyp_ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="206" mass="22568" checksum="47B5906A54175B1E" modified="2007-05-15" version="1" fragment="single">LMQSMNTAGIALFFKSSVTDRALAMPQVSCEDVSRVRWSHLKSLGFAGVVFDKDNTLTTPYALEVHEKVRASLEACKEAFGAENVAVYSNSAGLFQYDPDGKEADAMERALGIKFIRHATKKPAGDVDDVVAHFPSCDSAKKLIFVGDRYLTDVVYGNRHGMFTVRVAPFTTKGESLAIKSARKIEESVVALWRSLGVAPKPHELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7N0</accession>
    <name>A4S7N0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_43066</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421483.1">
        <property type="nucleotide sequence ID" value="XM_001421446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7N0"/>
    <dbReference type="STRING" id="436017.A4S7N0"/>
    <dbReference type="GeneID" id="5005458"/>
    <dbReference type="Gramene" id="ABO99776">
        <property type="protein sequence ID" value="ABO99776"/>
        <property type="gene ID" value="OSTLU_43066"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43066"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_6_1"/>
    <dbReference type="OMA" id="HVKVGFL"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000104">
        <property type="entry name" value="ATP-binding cassette sub-family F member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF14">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="3"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="315"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="539"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00061344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="631" mass="70990" checksum="9C63A83707A76996" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S886</accession>
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        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_27761</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC3 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S886"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:DNA replication initiation"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ORC3"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ORC_WH_C"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WHD_ORC"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="27"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 3 winged helix C-terminal" evidence="8">
        <location>
            <begin position="812"/>
            <end position="943"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="965" mass="104657" checksum="C37E504744102A11" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8C4</accession>
    <name>A4S8C4_OSTLU</name>
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        <submittedName>
            <fullName evidence="8">Chloroplast cytochrome c biogenesis protein, Ccs1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CCS1</name>
        <name evidence="8" type="ORF">OSTLU_27799</name>
    </gene>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="STRING" id="436017.A4S8C4"/>
    <dbReference type="GeneID" id="5005636"/>
    <dbReference type="Gramene" id="ABP00036">
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        <property type="gene ID" value="OSTLU_27799"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27799"/>
    <dbReference type="eggNOG" id="ENOG502QRFF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034630_0_0_1"/>
    <dbReference type="OMA" id="RFWIDYT"/>
    <dbReference type="OrthoDB" id="565797at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01392">
        <property type="entry name" value="CytC_Ccs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023494">
        <property type="entry name" value="Cyt_c_bgen_Ccs1/CcsB/ResB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007816">
        <property type="entry name" value="ResB-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31566">
        <property type="entry name" value="CYTOCHROME C BIOGENESIS PROTEIN CCS1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31566:SF0">
        <property type="entry name" value="CYTOCHROME C BIOGENESIS PROTEIN CCS1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05140">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
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        <location>
            <begin position="14"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="448" mass="48464" checksum="EEB730C0AED2B627" modified="2007-05-15" version="1">MGKKTLKSLSSLPLAIGELLVIAGFSALGTVIEQNKSFAWYVENYPTENKSLGFIDFPLILDLGLDHIYTTWYFLGLLGLLGASLTACTVTRQWPVWKVSAKWKFLDRRATLLAMEEAESVPRARLSDFSDLLADRGYQVFIKGKKMYAFKGLIGRLAPIGVHAALLFTLGGAAYSGLGGLSGSVMVPDGSSFEIASGLTRGSLLSSMPGIAKSSVQVNDFTIDYLPNGQVSQFYSDLSVVDPNGKEMSRKTISVNVPLRAGGVTMYQTDWALSSMQVTVAKPGADGETETENTYVLPMASLEGKGGFQGRIWGTFLPLSFDDDQRRGISLVARDFQSVAIYDSKGAFAGVRRPESKKPIVVDGIKLMLGDVKGSTGLELKTDPGVPLVYAGFAGLMVTSFLSLLSHSQIWAIQEETAIVVGGKTNRAKEEFRTELDEVLNSVPEYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8E9</accession>
    <name>A4S8E9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GPI inositol-deacylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8E9"/>
    <dbReference type="GeneID" id="5005694"/>
    <dbReference type="Gramene" id="ABP00051">
        <property type="protein sequence ID" value="ABP00051"/>
        <property type="gene ID" value="OSTLU_27826"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27826"/>
    <dbReference type="eggNOG" id="ENOG502QS8K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065036_0_0_1"/>
    <dbReference type="OMA" id="NACTTRE"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909:SF2">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="37657" checksum="DBE0490EA91E9D28" modified="2007-05-15" version="1">MRASDALSSTARTAFSPLRARASSKPPLARLAPLGLGQSLDAAKASRSDAFLTLTRASADVIDVSDASSDDTRVRASASANPIVVLSGFGNCSSDYEDALGNDEASLAKSLRSRGFSVHVAEVERKDWFVGILRGIFTKGFWMNACTTRESYGWYLERVDACVKEALRANPEATSVDIVAHSAGGWLARAFIGGALAMNASEVECSGDFLKRDERVRRLICLGTPHAQDAKSDPTRGASKWVNDTWPGAYFEPDVQYVCVTGRAVVGNASAEPKTIGKYAAGSYAVVAGGDGDGVEGDAVVPNCAALALEGAEMIVIDACWHSMSTVGTFDEPSKFHWYGSDAVVDRWLKVLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8W0</accession>
    <name>A4S8W0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421830.1">
        <property type="nucleotide sequence ID" value="XM_001421793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8W0"/>
    <dbReference type="GeneID" id="5005996"/>
    <dbReference type="Gramene" id="ABP00124">
        <property type="protein sequence ID" value="ABP00124"/>
        <property type="gene ID" value="OSTLU_27986"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27986"/>
    <dbReference type="HOGENOM" id="CLU_1985323_0_0_1"/>
    <dbReference type="OrthoDB" id="498557at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="126" mass="13612" checksum="1E5BF533FE972314" modified="2007-05-15" version="1">MTSRASRRRPTTRRPTRAYAPRARSSDDDDDATANESSTSATEPKLDPFGFGARRQDAPDEIRPGFDTAEGGKVGPVGTFFISALLIALFGGSFFFTSVPRGSVEELAARQLADDPNAPTQSFARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8X6</accession>
    <name>A4S8X6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DMT family transporter: UDP-galactose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_4844</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421835.1">
        <property type="nucleotide sequence ID" value="XM_001421798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8X6"/>
    <dbReference type="GeneID" id="5006007"/>
    <dbReference type="KEGG" id="olu:OSTLU_4844"/>
    <dbReference type="eggNOG" id="KOG1582">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036019_2_1_1"/>
    <dbReference type="OMA" id="TECHGLG"/>
    <dbReference type="OrthoDB" id="498421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF8">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="208" mass="22839" checksum="3AD8E1820D009D94" modified="2007-05-15" version="1" fragment="single">LKDYAMLSVMTSGSMYLTNAALSYINYTTRIVAKCSKVIPVMIVGTFMHGRRYGSEDYAMCVLLVIGITMFTMGDVDSFPNFNYRGVTYITIALFTESTAGNFEERRFFNIPQPISHCEVVFYVNAIGSAWIALGLFASGELFTAVAHLLGEPDVLAAICVAAAFGYISVTCILLCLRHYGATNTEVIKAVRKMLSLALSLVVYPKPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9L5</accession>
    <name>A4S9L5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422088.1">
        <property type="nucleotide sequence ID" value="XM_001422051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9L5"/>
    <dbReference type="GeneID" id="5006249"/>
    <dbReference type="Gramene" id="ABP00405">
        <property type="protein sequence ID" value="ABP00405"/>
        <property type="gene ID" value="OSTLU_28242"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28242"/>
    <dbReference type="HOGENOM" id="CLU_2965108_0_0_1"/>
    <dbReference type="OrthoDB" id="10471796at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="59" mass="6269" checksum="546955E93ED15DAF" modified="2007-05-15" version="1">MGLETALLRNHERLGKIALTGGFAFGFAYTTKTGTSPLAGWGWTPRTREASARAATAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9N1</accession>
    <name>A4S9N1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_93924</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:62432"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:16092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:82930"/>
            <dbReference type="EC" id="2.5.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TDD superfamily. DTWD2 family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422200.1">
        <property type="nucleotide sequence ID" value="XM_001422163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9N1"/>
    <dbReference type="STRING" id="436017.A4S9N1"/>
    <dbReference type="GeneID" id="5006257"/>
    <dbReference type="Gramene" id="ABP00517">
        <property type="protein sequence ID" value="ABP00517"/>
        <property type="gene ID" value="OSTLU_93924"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93924"/>
    <dbReference type="eggNOG" id="KOG4382">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066458_2_3_1"/>
    <dbReference type="OMA" id="ENSIGME"/>
    <dbReference type="OrthoDB" id="408541at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039262">
        <property type="entry name" value="DTWD2/TAPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392">
        <property type="entry name" value="TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392:SF0">
        <property type="entry name" value="TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="8">
        <location>
            <begin position="17"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="221"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="252" mass="28301" checksum="E45F1DC7FF90B473" modified="2007-05-15" version="1">MTSRCAPIRALDAATTRRPTCARCRRALVACACRSVARALGRAGRVANSTNIYILQDRAEFRRALGSAIVCELALDKCEVRVLFDDLRVRGRDVKAPFAEEDAARWGVLWPCDEAVDLAAHARDATTRRLENLIVLDSTWHRARAMYHRVPWLQRLRKFQIEPRRKSNYRIRKQPNDLCLSTAECVGEALLALDGENCGAERVAQAFDAMVDDQLDAERAAYHRGARERGAPTRPPSAVLARERDLRSPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9W2</accession>
    <name>A4S9W2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_18717</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422241.1">
        <property type="nucleotide sequence ID" value="XM_001422204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9W2"/>
    <dbReference type="GeneID" id="5006194"/>
    <dbReference type="Gramene" id="ABP00558">
        <property type="protein sequence ID" value="ABP00558"/>
        <property type="gene ID" value="OSTLU_18717"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18717"/>
    <dbReference type="HOGENOM" id="CLU_472835_0_0_1"/>
    <dbReference type="OMA" id="SQLGMMC"/>
    <dbReference type="OrthoDB" id="10445821at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051139">
        <property type="entry name" value="Mediator_complx_sub13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249:SF3">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="577" mass="61921" checksum="AEBFF979AE9EBBFE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9X8</accession>
    <name>A4S9X8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422249.1">
        <property type="nucleotide sequence ID" value="XM_001422212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9X8"/>
    <dbReference type="GeneID" id="5006306"/>
    <dbReference type="Gramene" id="ABP00566">
        <property type="protein sequence ID" value="ABP00566"/>
        <property type="gene ID" value="OSTLU_28351"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28351"/>
    <dbReference type="HOGENOM" id="CLU_1017036_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="274" mass="30710" checksum="28C9C116458550F1" modified="2007-05-15" version="1">MTRERFACSLYAKRGGDDGKWANLGRRACEPSVAHEGAMCPLFRDDATRRVRVQRSLLCSPTWRAPGWCDVKETPFHLVLERLKPALEYHRDDAKKVMIDKDALCAEKGKPFADVRFVLMDLCSNDERRLELDALAKARGGAPGNKLADVVLQLTPVEFSRAWRSTRARIGTKRDVTPAHEMPFEALADQYDDALVQANAVVGVEHYRQRKERLKAARQSKPFVKDDHTSPSHRLISVDDAVALGDFTAVASVKTNRAVGARSRRHQPPLTAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA26</accession>
    <name>A4SA26_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_41998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422168.1">
        <property type="nucleotide sequence ID" value="XM_001422131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA26"/>
    <dbReference type="GeneID" id="5006226"/>
    <dbReference type="Gramene" id="ABP00485">
        <property type="protein sequence ID" value="ABP00485"/>
        <property type="gene ID" value="OSTLU_41998"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41998"/>
    <dbReference type="eggNOG" id="ENOG502QQRH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053419_3_0_1"/>
    <dbReference type="OMA" id="PQGCAGN"/>
    <dbReference type="OrthoDB" id="2138282at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.10">
        <property type="entry name" value="PNP-oxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037119">
        <property type="entry name" value="Haem_oxidase_HugZ-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343">
        <property type="entry name" value="CREG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343:SF29">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CREG-like beta-barrel" evidence="2">
        <location>
            <begin position="59"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="314" mass="34887" checksum="D5D8F241464E675F" modified="2007-05-15" version="1">MKPSSSGETATRTVKDEALEIPFQSTSPRKRVGRTRLLRTPMAGGVVSRDTKDSNLPSMATAARNLMELADYGDLSTTMSDMHHRRAGYPFGSTVDFATDATGHPIFCLAPLAIHTRNIAADGKCSLTVKMSGWGGLANARVTIFGDVQRLPNGEYQTAANEIFKSKYHARKEAIDMEDRWGDYTYYRMNRIVDVYFVGGFGTLNWIKLDEYCSTSPDTIVTAAHGKSVIETLGELNTRFSQRLAAHMGNLLDLVVDDLWIISIDRRGMDVRVRTDGSSLIRRISFDTDVECFDDAKRAVECALTNDDLCRGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA57</accession>
    <name>A4SA57_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422320.1">
        <property type="nucleotide sequence ID" value="XM_001422283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA57"/>
    <dbReference type="GeneID" id="5006358"/>
    <dbReference type="Gramene" id="ABP00637">
        <property type="protein sequence ID" value="ABP00637"/>
        <property type="gene ID" value="OSTLU_28437"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28437"/>
    <dbReference type="HOGENOM" id="CLU_519177_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="525" mass="58051" checksum="82EA156FD2330A51" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA77</accession>
    <name>A4SA77_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422295.1">
        <property type="nucleotide sequence ID" value="XM_001422258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA77"/>
    <dbReference type="GeneID" id="5006392"/>
    <dbReference type="Gramene" id="ABP00612">
        <property type="protein sequence ID" value="ABP00612"/>
        <property type="gene ID" value="OSTLU_28459"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28459"/>
    <dbReference type="HOGENOM" id="CLU_746775_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="371" mass="42200" checksum="68D34C50E6E31711" modified="2007-05-15" version="1">MASPSLDAVRWSEYRALMQAWEAFNPHRELLRRFLQKQSHTEQCPPGVPYVPDLPEPEYFAVKRRIEAGETVPCPGFLRERDNRRNQCRCGAPLRVDDTGNISCTSKIPRHENYGPVPRCCCWAEEEHARNQRHDMPPYILRPPPIVSPPQVPPSSQVLLSFLEGVRPSMNANYLRCVQDIDEELARLNEQLADNSISTTRREAIQQHIVSERSKLEAKDTQLQDFFNTTTALAESVHTFEHRVAEKYQKAVDAYIKAQLDEVVVPPDSRGNPKFKDSVDGIDRELAKLESENGGISNDSARARVASKRKSVEECESEHKRLKTTSVEYNLSILKGSLEKDKSMSAEDKRRWECVINAVGLLRANDAPRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAK3</accession>
    <name>A4SAK3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RecA family profile 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_3270</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422446.1">
        <property type="nucleotide sequence ID" value="XM_001422409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAK3"/>
    <dbReference type="STRING" id="436017.A4SAK3"/>
    <dbReference type="GeneID" id="5006464"/>
    <dbReference type="Gramene" id="ABP00763">
        <property type="protein sequence ID" value="ABP00763"/>
        <property type="gene ID" value="OSTLU_3270"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3270"/>
    <dbReference type="eggNOG" id="ENOG502QQ01">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018264_0_1_1"/>
    <dbReference type="OMA" id="ANMIKCV"/>
    <dbReference type="OrthoDB" id="41505at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000050">
        <property type="entry name" value="DNA repair protein RadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32472">
        <property type="entry name" value="DNA REPAIR PROTEIN RADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32472:SF10">
        <property type="entry name" value="DNA REPAIR PROTEIN RADA-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13481">
        <property type="entry name" value="AAA_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13541">
        <property type="entry name" value="ChlI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Zn_ribbon_LapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01874">
        <property type="entry name" value="DNAREPAIRADA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="12">
        <location>
            <begin position="67"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="478" mass="49993" checksum="F5BA8655EED27A68" modified="2007-05-15" version="1" fragment="single">SQTKTAYVCAECGEDSRQWLGQCPACKSWDTMKAIALAPTSGGGAGKASAGGGAGARARQTMPRMRLREELGKEIERVLGGGVVPGGMILVGGDPGVGKSTILLQLAGLLGARGEEREGEEDGANESIAAGGVLYASGEESVEQVAGRAERMGIDPNGIYLYSATRLENILEAVSTLKPAALVVDSIQTVFLEDATGSPGSVSQVRECATALLHAAKTTGMPVFIIGHVTKSGDIAGPRVLEHIVDVVLYLEGDADRAVRILRGHKNRYGSTDEVGVFQMSDGGMKPVASPSALFLGERILSPDVSAAPTVTVQGSRPFMLEVQALTNERADAGEGGGMSAPPIRTAVGLRFERMQLLLAVLAKFVLGRRLQKHDVFINIVGGMKLEDPSTDVAVALAIASSFVEKPLPPDMCFFGEVGLGGELRPVMQAERRIAEAATMGFKRVLLPEAGSSPEMGKKTGIELVRCNTLADALEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAM2</accession>
    <name>A4SAM2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422457.1">
        <property type="nucleotide sequence ID" value="XM_001422420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAM2"/>
    <dbReference type="GeneID" id="5006692"/>
    <dbReference type="Gramene" id="ABP00774">
        <property type="protein sequence ID" value="ABP00774"/>
        <property type="gene ID" value="OSTLU_29309"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29309"/>
    <dbReference type="HOGENOM" id="CLU_1752778_0_0_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16280" checksum="77DE35A027582F1B" modified="2007-05-15" version="1">MTRDEIESEFELVDASDVPTIGWWDASRGCETVAEAQTRARGVAKYLMHKARAMAAGEEEEMDVCIVTHGMFIDMLLKTLFDVPRTRGKQGALFCSQNACVHELHLDIAEDGDSVGLQVFNDVTHIPEEARSGGTVDGLSEAYTNEGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAQ9</accession>
    <name>A4SAQ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic</fullName>
            <ecNumber evidence="3">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_43686</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="3"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422478.1">
        <property type="nucleotide sequence ID" value="XM_001422441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAQ9"/>
    <dbReference type="STRING" id="436017.A4SAQ9"/>
    <dbReference type="GeneID" id="5006536"/>
    <dbReference type="Gramene" id="ABP00795">
        <property type="protein sequence ID" value="ABP00795"/>
        <property type="gene ID" value="OSTLU_43686"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43686"/>
    <dbReference type="eggNOG" id="KOG2835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045637_0_1_1"/>
    <dbReference type="OMA" id="CEPFKVE"/>
    <dbReference type="OrthoDB" id="9991235at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009733">
        <property type="term" value="P:response to auxin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01414">
        <property type="entry name" value="SAICAR_synt_Sc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000199">
        <property type="entry name" value="Phosphoribosylaminoimidazole-succinocarboxamide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000015">
        <property type="entry name" value="Phosphoribosylaminoimidazole-succinocarboxamide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009251">
        <property type="entry name" value="PRK12607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR synthetase/ADE2 N-terminal" evidence="12">
        <location>
            <begin position="72"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="367" mass="41164" checksum="AA8A9AF10202AAA9" modified="2007-05-15" version="1">MSAPARASHASPQRVFSNAASKFRARQTPSKSARARRVRAKATHDDALRKSQALEALDACVTASDLGTGTKYEGKVRDTYVTGDTMIAVTTDRQSAFDRHLAYIPFKGAVLNQTSQWWFKQTEHIVPNAVVATPDPNVTVMRRCEVFPIEFVVRGYLTGSTSTSLWTHYKTGGRNYCGNALDDGMVKNQKLPANIVTPTTKEKEHDRPISLEDIVKEGWMKQDDLDYCVAKTLEVFAYAQEVAATRGLILVDTKYEFGRDADGTIRLIDEINTPDSSRYWLSNSYVERHAAGMEPDMIDKEFLRLWFAERCDPYKDETLPEAPADLVAELSSRYVKLYEMITGETFDVPPAGVDVNKRMRDALKGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB55</accession>
    <name>A4SB55_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphofructokinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_29493</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422557.1">
        <property type="nucleotide sequence ID" value="XM_001422520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB55"/>
    <dbReference type="STRING" id="436017.A4SB55"/>
    <dbReference type="GeneID" id="5006775"/>
    <dbReference type="Gramene" id="ABP00874">
        <property type="protein sequence ID" value="ABP00874"/>
        <property type="gene ID" value="OSTLU_29493"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29493"/>
    <dbReference type="eggNOG" id="KOG2440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020655_7_4_1"/>
    <dbReference type="OMA" id="ECIDSNC"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000002">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050929">
        <property type="entry name" value="PFKA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012004">
        <property type="entry name" value="PyroP-dep_PFK_TP0108"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005301">
        <property type="entry name" value="PRK06830.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45770">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000534">
        <property type="entry name" value="PPi_PFK_TP0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="11">
        <location>
            <begin position="67"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="416" mass="44085" checksum="0B112C33124DA45C" modified="2007-05-15" version="1">MRKTNFVSNSDRILLNSVAYGSAADPTQTCSLSSDVYDPSGCDYVPEWVVRAGPRAEVYFDPEEVHAAVVTCGGLCPGINDVIRSLVNTLEVGYGVKKISGVRYGFKGFFSGDEFMPLNRKVVRNIHNIGGSALGSGRGGGDVEKIVESIVNNGINMVFVIGGNGTHAGANAISNECAKRGVKVSVVGVPKTIDNDILLLDKTFGFDTAVEEAQKAIQAAAIEAQSAYRGVGVVKLMGRQSGFIAMFATLANGQVDCCLIPEISWAAHGPNGVVEYVRNMLDAQGHAVVVLAEGAGQEFVSAGGTDAGGNPKLGDIGQWFCKQLKAEIKCDVKYIDPTYMVRGCVANAHDSIMCTVLGQNAVHGAFAGFTGISVGSVSAHTAFLPIPRMIERERLVDPDGRMWHRTLASTGQPDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB57</accession>
    <name>A4SB57_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_9266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422718.1">
        <property type="nucleotide sequence ID" value="XM_001422681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB57"/>
    <dbReference type="STRING" id="436017.A4SB57"/>
    <dbReference type="GeneID" id="5006617"/>
    <dbReference type="Gramene" id="ABP01035">
        <property type="protein sequence ID" value="ABP01035"/>
        <property type="gene ID" value="OSTLU_9266"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9266"/>
    <dbReference type="eggNOG" id="ENOG502S8SW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114306_1_2_1"/>
    <dbReference type="OMA" id="KQPEFFP"/>
    <dbReference type="OrthoDB" id="793at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="entry name" value="Ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_bL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_bL31_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001809">
        <property type="entry name" value="PRK00528.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L31, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL31C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP01035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="71" mass="7822" checksum="872DB169B5EAD3E0" modified="2007-05-15" version="1" fragment="single">PEWFEEAKVFCNGEEVMTVGGTQAEYVVDIWSGNHPFFQGRSSAIMTDAGQVSRFANRFGDLGDLSAVETM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB67</accession>
    <name>A4SB67_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422563.1">
        <property type="nucleotide sequence ID" value="XM_001422526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB67"/>
    <dbReference type="GeneID" id="5006781"/>
    <dbReference type="Gramene" id="ABP00880">
        <property type="protein sequence ID" value="ABP00880"/>
        <property type="gene ID" value="OSTLU_29503"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29503"/>
    <dbReference type="HOGENOM" id="CLU_790825_0_0_1"/>
    <dbReference type="OMA" id="HSPAKEC"/>
    <dbReference type="OrthoDB" id="10604828at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="37247" checksum="C1F79886854634CE" modified="2007-05-15" version="1">MDRHAFFAAQAWLTATTTRARDGARASDDGDGDDGATREREEIYAGTCSFSCADEEQYETRAIATMDGDDAADDGEDDAADDGEEDAAENGRGRRRARPRGALARDAQHLTFGTTATLRDPASVRVSFAAVKTTFGASSGTGSGSTSVGDATTANARARIELECELDGQTYRMSTRTCRAVVKSFKETARSGHTEAFPRYLSVIFPHVTMNVYSAAESDASWDGLRALARALTDPALATTKTTTTTSENYDDGHDTDPDGNDPSPVGVGKPNPLPRSIGNEIDLETVALADADAFAAQRFAADALCDAARLLVADGDPWRTLSHDLLAHGVRDVFADDPSAYAGRAFPGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBG6</accession>
    <name>A4SBG6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aldose 1-epimerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_51907</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldose epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422614.1">
        <property type="nucleotide sequence ID" value="XM_001422577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBG6"/>
    <dbReference type="STRING" id="436017.A4SBG6"/>
    <dbReference type="GeneID" id="5006672"/>
    <dbReference type="Gramene" id="ABP00931">
        <property type="protein sequence ID" value="ABP00931"/>
        <property type="gene ID" value="OSTLU_51907"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51907"/>
    <dbReference type="eggNOG" id="KOG1604">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031753_2_0_1"/>
    <dbReference type="OMA" id="CTFIIDA"/>
    <dbReference type="OrthoDB" id="274691at2759"/>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09019">
        <property type="entry name" value="galactose_mutarotase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047215">
        <property type="entry name" value="Galactose_mutarotase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF0">
        <property type="entry name" value="GALACTOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="38"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="159"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>beta-D-galactose</name>
            <dbReference type="ChEBI" id="CHEBI:27667"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="259"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>beta-D-galactose</name>
            <dbReference type="ChEBI" id="CHEBI:27667"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>beta-D-galactose</name>
            <dbReference type="ChEBI" id="CHEBI:27667"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="47874" checksum="FF98EB5F971F3D08" modified="2007-05-15" version="1">MAKRSEPKPANAEDNSQTGKIAIVALAALGLAIKSRVARSKADAKPFVTRLPTATNSTPGASSSVDKSPSGRALRSPLRPRDSSTRDHAAEGLALIELEARGVAVSVSPFGATIVSLRAARRGDADEKDDVVLGFDDCESYDEVEGRPYFGAVCGRVANRIARGEFAVGRRTHTLAKNNGENTLHGGTSGWDRKRWTVEDQTRSSVTLSYVSVDGEEGFPANVKMYVVYSVLCVRNCAEVTTKMTATADAMTPISTVQHTYFNLNGHACGEDCSSHVVEMPNCDRYVPVNEDTLIPTGEGLRKVDGTAFDLRSPTPMFEKSSEGYDNTFVIAGADATRPTSELPRAAPRLAARVTCEDAGRVLEVLTDAPGVHLYTGNFLSENMVGKKKERARYRKHGGFCLETGWFPDAVNQHSKIGASYPSVMVNRGDTYSHTLTYRLSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBH5</accession>
    <name>A4SBH5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_19144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422619.1">
        <property type="nucleotide sequence ID" value="XM_001422582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBH5"/>
    <dbReference type="GeneID" id="5006677"/>
    <dbReference type="Gramene" id="ABP00936">
        <property type="protein sequence ID" value="ABP00936"/>
        <property type="gene ID" value="OSTLU_19144"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19144"/>
    <dbReference type="HOGENOM" id="CLU_951199_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="293" mass="31026" checksum="58575C8A422CD0F1" modified="2007-05-15" version="1">MHARAAIVSASASIARGTESSHSEPFVPSARVVDENAHAELRCAGKTSREELSPSQRARALAGIMDAASALGTRAPLSPLGNGTTPLRRARSLMAEAATTSAANGLKQIRASRANRASSAGARDAEENLDALEDEAPRRAASDAASVASASALDAANAIAKYADRERQLVAFMKEMASSADARLNDALDALSASEAQREEELAAMALAADAEREALEFSILLENKARVKERERVVELETLLALKQREIDALAAERGGARPSAAAVRYAANVRDEVKAILRAEFKRELADELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBI6</accession>
    <name>A4SBI6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422627.1">
        <property type="nucleotide sequence ID" value="XM_001422590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBI6"/>
    <dbReference type="STRING" id="436017.A4SBI6"/>
    <dbReference type="GeneID" id="5006685"/>
    <dbReference type="Gramene" id="ABP00944">
        <property type="protein sequence ID" value="ABP00944"/>
        <property type="gene ID" value="OSTLU_29623"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29623"/>
    <dbReference type="eggNOG" id="ENOG502R0ZN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_817209_0_0_1"/>
    <dbReference type="OMA" id="FAPCDVH"/>
    <dbReference type="OrthoDB" id="1908108at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006734">
        <property type="entry name" value="PLATZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31065">
        <property type="entry name" value="PLATZ TRANSCRIPTION FACTOR FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31065:SF35">
        <property type="entry name" value="PLATZ TRANSCRIPTION FACTOR FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04640">
        <property type="entry name" value="PLATZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="328" mass="35567" checksum="43F0292F0C58C821" modified="2007-05-15" version="1">MRPSARGDGGLTTRARATTARERSQGAKAQLPKELSWIPDLVHGAFFAPCDVHSTGSKGEQVNLFSLSSRRSMCPACAAERDVFDTIQIRRSSYHNVVRVQDVCKLMDVTGIQTYIINSARVVFLNERPHPRSTNKKDGEKLMNHSSSSGRGAGSGERYRAGAGAQAQMHSECSYCARILQSDNNKYCSISCKMNGGEDMSAKGGIDMSYAEETIKPTPRKSTQAKNAAKAEKANSDRRSPARNKSPASDTSTKRARGYSPVSVKSEDEYSPSSEGATPMRAVAAATTGKRKYSSKDRNGDAPVTPTLLIVTPAVPHRRKSKPKKSPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQG0</accession>
    <name>A4RQG0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle 19 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_10601</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415727.1">
        <property type="nucleotide sequence ID" value="XM_001415690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQG0"/>
    <dbReference type="STRING" id="436017.A4RQG0"/>
    <dbReference type="GeneID" id="5000058"/>
    <dbReference type="Gramene" id="ABO94019">
        <property type="protein sequence ID" value="ABO94019"/>
        <property type="gene ID" value="OSTLU_10601"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10601"/>
    <dbReference type="eggNOG" id="KOG3198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064201_2_1_1"/>
    <dbReference type="OMA" id="HTEICAI"/>
    <dbReference type="OrthoDB" id="497412at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006617">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="entry name" value="Signal recognition particle, SRP19-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0733">Signal recognition particle</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11916" checksum="04B1B629FD3B5317" modified="2007-05-15" version="1" fragment="single">VVVYPPYIDAARSVAKGRRIAREDAVEHPHALEVADACERALGMRCELEDKAYSRDFWCRGRVRVEWKRDDGSFVREELNTRGKLLRAIAAAVKAHPERGENGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQP4</accession>
    <name>A4RQP4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415770.1">
        <property type="nucleotide sequence ID" value="XM_001415733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQP4"/>
    <dbReference type="GeneID" id="4999853"/>
    <dbReference type="Gramene" id="ABO94062">
        <property type="protein sequence ID" value="ABO94062"/>
        <property type="gene ID" value="OSTLU_13639"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13639"/>
    <dbReference type="HOGENOM" id="CLU_1158027_0_0_1"/>
    <dbReference type="OMA" id="WRAYFRA"/>
    <dbReference type="OrthoDB" id="10571632at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="24938" checksum="FE925E56CC753D0A" modified="2007-05-15" version="1">MAKVRGRAPRSAAEGDARRARASGARMSRVDEALGALPATRAPDAHHGARDALTPLGLAKWRAYFRAQPPLAEGIDCATEIPGVSAGYELRTGRANELEPLLRQALPIAKMNLEAPDRATLTRAFGGLGKGAPFALSEEDKGAVAPAIVALKALRATEAKKAEGGDETSAREKKKRKRESKKEKKDKRKRTDDGGQTTSQGVSAGISTGDSDGTRNTGAATAATAATASGGDAPSEPMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR00</accession>
    <name>A4RR00_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Down syndrome critical region protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_6250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415480.1">
        <property type="nucleotide sequence ID" value="XM_001415443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR00"/>
    <dbReference type="STRING" id="436017.A4RR00"/>
    <dbReference type="GeneID" id="4999969"/>
    <dbReference type="Gramene" id="ABO93772">
        <property type="protein sequence ID" value="ABO93772"/>
        <property type="gene ID" value="OSTLU_6250"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6250"/>
    <dbReference type="eggNOG" id="KOG2717">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056829_0_0_1"/>
    <dbReference type="OMA" id="CVTMPIT"/>
    <dbReference type="OrthoDB" id="10263384at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048768">
        <property type="term" value="P:root hair cell tip growth"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="27602" checksum="7B9A741E7EA66216" modified="2007-05-15" version="1" fragment="single">HNGVLLTACGNVQLRVGDSSVSVLESLFMVVEPVRVLDVSLVLAPPGRLAVGVHAFPFSFTLGSFPPTTPMYETFHGQNTQIVYAIDAEVVRPILRGGSLSTGMCEFLVETKPDEDDVADAAASETMAFEITEERQDLGPAPGLLASEGFLIRGSFDKTSWFLEEAITGRLVVERSAAPLRAIEIELCRIEGCSTSEGQVVSETSPVQFTQIVDGDCPRGVEIPIHVVIPRLFACPSVQAPTFSVAFMLRVLCVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR64</accession>
    <name>A4RR64_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SURP motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_86131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415844.1">
        <property type="nucleotide sequence ID" value="XM_001415807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR64"/>
    <dbReference type="STRING" id="436017.A4RR64"/>
    <dbReference type="GeneID" id="4999745"/>
    <dbReference type="Gramene" id="ABO94136">
        <property type="protein sequence ID" value="ABO94136"/>
        <property type="gene ID" value="OSTLU_86131"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86131"/>
    <dbReference type="eggNOG" id="KOG0007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013259_1_0_1"/>
    <dbReference type="OMA" id="KANNVPT"/>
    <dbReference type="OrthoDB" id="447637at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01800">
        <property type="entry name" value="Ubl_SF3a120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000002">
        <property type="entry name" value="Splicing factor 3A subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000001">
        <property type="entry name" value="Splicing factor 3a, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SF3A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022030">
        <property type="entry name" value="SF3A1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035563">
        <property type="entry name" value="SF3As1_ubi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
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        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316">
        <property type="entry name" value="SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316:SF1">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12230">
        <property type="entry name" value="PRP21_like_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SURP motif" evidence="8">
        <location>
            <begin position="46"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="8">
        <location>
            <begin position="156"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="461"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="461"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="635" mass="69431" checksum="0EA8FBAB70F1C72E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRK3</accession>
    <name>A4RRK3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415916.1">
        <property type="nucleotide sequence ID" value="XM_001415879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRK3"/>
    <dbReference type="GeneID" id="4999856"/>
    <dbReference type="Gramene" id="ABO94208">
        <property type="protein sequence ID" value="ABO94208"/>
        <property type="gene ID" value="OSTLU_92178"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92178"/>
    <dbReference type="HOGENOM" id="CLU_1333849_0_0_1"/>
    <dbReference type="OMA" id="YCETSPL"/>
    <dbReference type="OrthoDB" id="495748at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="206" mass="22448" checksum="BA91CBFF6C4DD6DA" modified="2007-05-15" version="1">MSLGQTIGTRVAGTRAFAASADAPLLVTMIGAQKPVSEVHRMIEASGAEIKESRNVRLGGRASNMFLVTNVDPMALKKQFEGQVFDFFSVFPAKNTVQDIKGPYCETSPLLPYVRKATMSVPFKKGVVNEITEFLCSKGVTLSHMDEYRSGKDIVLECIMHLPTGLAEFPSVDDKYVLQNLEALGCTVAEFGRVEGRPQAEKAAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRW5</accession>
    <name>A4RRW5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_40154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415974.1">
        <property type="nucleotide sequence ID" value="XM_001415937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRW5"/>
    <dbReference type="GeneID" id="5000046"/>
    <dbReference type="Gramene" id="ABO94266">
        <property type="protein sequence ID" value="ABO94266"/>
        <property type="gene ID" value="OSTLU_40154"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40154"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_7_1"/>
    <dbReference type="OMA" id="HRNVPKD"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF12">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="282" mass="30892" checksum="78AC2F023A866D51" modified="2007-05-15" version="1">MRAVRAFASRTDVTAPVPFATLVQGASRGIGLELARQMLERDRDVFRGKSHGGVVVATCRDPDNADGLKELQKAHGDRLRVLRVDAKDEASMKAAAATVEREFGRLDFMANVSAVLSEGKMRPETSIARTEAENMVESYRVNALGPTMMMKHFSPLMLKTAELNLAGNAHVPVIANWSARVSSIGDNALGGWHSYRASKTALNQLTRNCSIEFARKKHPIIAMCVHPGTVDTKLSEPFKKNVPADKLFTPEYAVTRLLEVIGGATLEHSGNLYDYAGEKIDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSA6</accession>
    <name>A4RSA6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416523.1">
        <property type="nucleotide sequence ID" value="XM_001416486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSA6"/>
    <dbReference type="STRING" id="436017.A4RSA6"/>
    <dbReference type="GeneID" id="5000327"/>
    <dbReference type="Gramene" id="ABO94816">
        <property type="protein sequence ID" value="ABO94816"/>
        <property type="gene ID" value="OSTLU_24150"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24150"/>
    <dbReference type="eggNOG" id="ENOG502QQNB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033094_0_0_1"/>
    <dbReference type="OMA" id="IGQHIFH"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="75"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="387" mass="42782" checksum="8E5503151AA47B89" modified="2007-05-15" version="1">MRVLLNPNSVCMNTGSKENTMHKEFPSRAAVLSNIPDECFKKDTAKSLMYAAVSTAMTVGCGLIAAATLPLQAAWWPAWLAYAAVNGTIATGCWVIAHECGHNAFSDNRFIQDAVGYALHSALLVPYFSWQRSHAVHHSRTNHLTEGETHVPYVKGELKGDLNLKAKKNLGEGPFAILQLVTHLVFGWPAYLLTGATGGSARGVTNHFLPNINTGALELFPGSWKKKVYYSDIGVFAFVGVLAAWVAQCGWAPFVALYLGPYLFVNFWLVLYTWLQHTDVDVQHLAADEWSYIKGAFLTIDRPYGPVFDFLHHRIGSTHVAHHVECAIPHYKAVEATEALKTKYPEYYLYDPTPIWAAMMRVASKCVAVEKRGEGKGAMWTFTDGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSF9</accession>
    <name>A4RSF9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416497.1">
        <property type="nucleotide sequence ID" value="XM_001416460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSF9"/>
    <dbReference type="GeneID" id="5000484"/>
    <dbReference type="Gramene" id="ABO94790">
        <property type="protein sequence ID" value="ABO94790"/>
        <property type="gene ID" value="OSTLU_14350"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14350"/>
    <dbReference type="HOGENOM" id="CLU_941323_0_0_1"/>
    <dbReference type="OrthoDB" id="10508083at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="32570" checksum="C25B049B606957D6" modified="2007-05-15" version="1">MAMAFEALEARARRARERETGSSSSDGERARANASEATRRLEELEDRLRSATTTLRATHEELERERKRCAELDAALARARDSTTAAFGEKIQTTRELAEAVAALEGEKADAMHERARLLERMDALERDGVVDGAVMNENLRIELANERAKRGDLEEALTDLKLASDASMELSVALRQEVEALRSSGAQPSVSLINIEPTDEIPPRAASAIEAHLIWRRRDARNEPGDASSDWVKAESIVTDRLARADGARVVYWAYLNALAELLRVGDVAAFDQTSWRALGDFVARVLAASRASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSL3</accession>
    <name>A4RSL3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_30214</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416476.1">
        <property type="nucleotide sequence ID" value="XM_001416439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSL3"/>
    <dbReference type="GeneID" id="5000076"/>
    <dbReference type="Gramene" id="ABO94769">
        <property type="protein sequence ID" value="ABO94769"/>
        <property type="gene ID" value="OSTLU_30214"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30214"/>
    <dbReference type="HOGENOM" id="CLU_2965110_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="HIG1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="59" mass="6126" checksum="88D368F6110C83EC" modified="2007-05-15" version="1">MSVKLIHSRLYAQAATLAALGAAASLEMDGGREATAATARDPHEYRARRRGGGDDARGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP4</accession>
    <name>A4RSP4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416213.1">
        <property type="nucleotide sequence ID" value="XM_001416176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP4"/>
    <dbReference type="GeneID" id="5000298"/>
    <dbReference type="Gramene" id="ABO94506">
        <property type="protein sequence ID" value="ABO94506"/>
        <property type="gene ID" value="OSTLU_30177"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30177"/>
    <dbReference type="HOGENOM" id="CLU_2254679_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="104" mass="11416" checksum="0D0462214BE0314E" modified="2007-05-15" version="1">MDDLIVVRCNRDVSKSSLISHVTRTSSAYFETDGVERGERSLGDPGALADSEVWVLTDNGQMLKVADVNQVLPVKLIETASGYVVYSLLLYGLAYSRPQGTYQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSV7</accession>
    <name>A4RSV7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chloroplast thylakoid protein kinase STN7, probable</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Snt8</name>
        <name evidence="8" type="ORF">OSTLU_119560</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416427.1">
        <property type="nucleotide sequence ID" value="XM_001416390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSV7"/>
    <dbReference type="STRING" id="436017.A4RSV7"/>
    <dbReference type="GeneID" id="5000097"/>
    <dbReference type="Gramene" id="ABO94720">
        <property type="protein sequence ID" value="ABO94720"/>
        <property type="gene ID" value="OSTLU_119560"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119560"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_558197_0_0_1"/>
    <dbReference type="OMA" id="GCCEIDQ"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE STN8, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STN7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="168"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="486" mass="53802" checksum="CD6B300717B786B8" modified="2007-05-15" version="1">MNRSLALVAIVNAATSKKVQLKNKKLSSGRKRVTCGSSRQESFQTTLKRPLGLILQPQNDDKGAYVADISPRSHAADCGIISVGDIIDAIEINNVALTGCSGVYFDDIISFISTQKSVQVKLTFSRPETFSIESEDMASYWEKKRNERLNSPAVLRRTVGVQPEDIRISKSGPLGEGSFGTVFRGTWKERDVVLKCAKRNVYGATELLDAELELNEAVHKLAKGSCARFFGCCEIDQRQEGQIYNGTLPAGLWLMWEYCGSVTLGEALRKPETLETITRKAYNLSQSTTECEMIKLVLRSILKNLESLHSVGIVHRDIKPDNIVFSEEGGVVFIDLGAAAQCLGVPKNYVPGEGPADPRYCSADDIYLLPSTAPQPTADNLSELWEIYQPGKFDMFSVGIVMLQLCFPYLRDSERLLTFKNEVARHRYDLSEWRTHDRVVVSSSCRGEALLDAAQGAGWALATALLTPKREDRISALDAISHSFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT94</accession>
    <name>A4RT94_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">OSTLU_44713</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416112.1">
        <property type="nucleotide sequence ID" value="XM_001416075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT94"/>
    <dbReference type="STRING" id="436017.A4RT94"/>
    <dbReference type="GeneID" id="5000123"/>
    <dbReference type="Gramene" id="ABO94404">
        <property type="protein sequence ID" value="ABO94404"/>
        <property type="gene ID" value="OSTLU_44713"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44713"/>
    <dbReference type="eggNOG" id="KOG0969">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000203_2_0_1"/>
    <dbReference type="OMA" id="CNNCRPR"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="17 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="22">
        <location>
            <begin position="116"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="21">
        <location>
            <begin position="414"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="23">
        <location>
            <begin position="890"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ABO94404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="982" mass="110536" checksum="BCBB60309A5FA70F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTB7</accession>
    <name>A4RTB7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Chorismate synthase</fullName>
            <ecNumber evidence="4 9">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_29930</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the last common step of the biosynthesis of aromatic amino acids, produced via the shikimic acid pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 9"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416103.1">
        <property type="nucleotide sequence ID" value="XM_001416066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTB7"/>
    <dbReference type="STRING" id="436017.A4RTB7"/>
    <dbReference type="GeneID" id="5000271"/>
    <dbReference type="Gramene" id="ABO94395">
        <property type="protein sequence ID" value="ABO94395"/>
        <property type="gene ID" value="OSTLU_29930"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29930"/>
    <dbReference type="eggNOG" id="KOG4492">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034547_0_1_1"/>
    <dbReference type="OMA" id="MLSINAV"/>
    <dbReference type="OrthoDB" id="1721239at2759"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.150.10:FF:000003">
        <property type="entry name" value="Chorismate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="entry name" value="Chorismate synthase AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003793">
        <property type="entry name" value="PRK05382.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085:SF0">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="Chorismate synthase, AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00053861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="458" mass="48939" checksum="DCA32D8C41E9F7CC" modified="2007-05-15" version="1">MRTARATSKPSARAARSTTKSTRTATGRTRPARCPDAGDARRGARTIPRAGSTFGRIFRVTTFGESHGGGVGCVVDGVPPRLRVTREELQFELDRRRPGQSRITTPRNEEDSCEILSGVGLDGVTLGTPVAVLVRNKDQRSQDYGEIAVAYRPSHADATYDMKYGVRAIAGGGRSSARETIGRVAAGAIAKKVLKEVAGTEILAYVSAVRDVKTTAVNHETMTMDDVESNIVRCPDESCAQKMIDAIDEVRVKGDSCGGVVTCVVRNPPRGLGAPAFDKLEADLAKAMLSLPATKGFEIGSGFDGTLQKGSEHNDEFFMDSEKGLRTRTNRSGGIQGGISNGEMIEMKIAFKPTSTITQAQNTVNRDGVETELKARGRHDPCVVPRAVPMVEAMVALTLVDHLMLQHAQCNLIDAGDLTELVQGNLPTLYDPEAIAAAAAASKAQMTTKDMSDAFSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTC4</accession>
    <name>A4RTC4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Unk4</name>
        <name evidence="3" type="ORF">OSTLU_119396</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416101.1">
        <property type="nucleotide sequence ID" value="XM_001416064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTC4"/>
    <dbReference type="STRING" id="436017.A4RTC4"/>
    <dbReference type="GeneID" id="5000210"/>
    <dbReference type="Gramene" id="ABO94393">
        <property type="protein sequence ID" value="ABO94393"/>
        <property type="gene ID" value="OSTLU_119396"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119396"/>
    <dbReference type="HOGENOM" id="CLU_471437_0_0_1"/>
    <dbReference type="OMA" id="CFRMREG"/>
    <dbReference type="OrthoDB" id="495655at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="594" mass="65708" checksum="3E3BCFAB27B027BD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTS0</accession>
    <name>A4RTS0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD/PDEase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_7743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416544.1">
        <property type="nucleotide sequence ID" value="XM_001416507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTS0"/>
    <dbReference type="STRING" id="436017.A4RTS0"/>
    <dbReference type="GeneID" id="5001113"/>
    <dbReference type="Gramene" id="ABO94837">
        <property type="protein sequence ID" value="ABO94837"/>
        <property type="gene ID" value="OSTLU_7743"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7743"/>
    <dbReference type="eggNOG" id="ENOG502QSR7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036524_2_2_1"/>
    <dbReference type="OMA" id="GHDWFHI"/>
    <dbReference type="OrthoDB" id="16547at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.50">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33594:SF1">
        <property type="entry name" value="HD_PDEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33594">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03035)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="222" mass="24723" checksum="BCAAE3932803446E" modified="2007-05-15" version="1" fragment="single">VARAERFARDALASNDGSHDLWHVERVRASAVALARLEGANAFVCELAALLHDVDDWKYARGDGAKGRARTFLEDSCADVDAATRETVLDVCARIGFKSELEKAEKSRADDDEESVEFRCVQDADRLDAIGAIGIGRTFCFGGARGNPMHVPGVPPMVDVTAARYEAAHRDETRPNTTINHFHEKLFRLRGLMKTASGRARAERRHATMVEFVERFHREWDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTS7</accession>
    <name>A4RTS7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Small nuclear ribonucleoprotein Sm D3</fullName>
            <shortName evidence="8">Sm-D3</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">snRNP core protein D3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_9203</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
            <location evidence="8">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
        <text evidence="8">SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the snRNP core protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416549.1">
        <property type="nucleotide sequence ID" value="XM_001416512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTS7"/>
    <dbReference type="STRING" id="436017.A4RTS7"/>
    <dbReference type="GeneID" id="5000898"/>
    <dbReference type="Gramene" id="ABO94842">
        <property type="protein sequence ID" value="ABO94842"/>
        <property type="gene ID" value="OSTLU_9203"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9203"/>
    <dbReference type="eggNOG" id="KOG3172">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099537_1_2_1"/>
    <dbReference type="OMA" id="HESEGHV"/>
    <dbReference type="OrthoDB" id="6425924at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01721">
        <property type="entry name" value="Sm_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000002">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034099">
        <property type="entry name" value="SmD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="9">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="10804" checksum="8019B819B6367C0D" modified="2007-05-15" version="1" fragment="single">LGKGVGVPVKLLHESEGHVVTVELKTGETYRGQLVESEDNWNCQMTDVTHVGRDGKESKMEHVYIRGSKVRMMVIPDMLKHAPMFKRIDPKFDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUB3</accession>
    <name>A4RUB3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_7508</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416930.1">
        <property type="nucleotide sequence ID" value="XM_001416893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUB3"/>
    <dbReference type="STRING" id="436017.A4RUB3"/>
    <dbReference type="GeneID" id="5001078"/>
    <dbReference type="Gramene" id="ABO95223">
        <property type="protein sequence ID" value="ABO95223"/>
        <property type="gene ID" value="OSTLU_7508"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7508"/>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_18_15_1"/>
    <dbReference type="OMA" id="DEIANCK"/>
    <dbReference type="OrthoDB" id="566279at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF46">
        <property type="entry name" value="LEUCINE RICH REPEAT-CONTAINING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="4">
        <location>
            <begin position="41"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="149" mass="16050" checksum="E6224E014DDA97BA" modified="2007-05-15" version="1" fragment="single">LRNLDATNNKLREIPREIGNCVNITRLVLAANVIETLPDEIGALVKLKTLIVDGNRLRALPATIGSLKALQTLSACECELSTIPTTISTCIALTTVKFARNKSLDSSALDALADCERLEEIDASACALTVIPAALGRLKRLRKLNIDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUD8</accession>
    <name>A4RUD8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416654.1">
        <property type="nucleotide sequence ID" value="XM_001416617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUD8"/>
    <dbReference type="STRING" id="436017.A4RUD8"/>
    <dbReference type="GeneID" id="5000938"/>
    <dbReference type="Gramene" id="ABO94947">
        <property type="protein sequence ID" value="ABO94947"/>
        <property type="gene ID" value="OSTLU_30586"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30586"/>
    <dbReference type="eggNOG" id="KOG3456">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1889252_0_0_1"/>
    <dbReference type="OMA" id="IPIHADR"/>
    <dbReference type="OrthoDB" id="496460at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="135" mass="14133" checksum="4516BBC9FC8D69E0" modified="2007-05-15" version="1">MAIARGEDATRTVTVARTVTRAHATTAPTIPSKPSQPVQTKRPGKLPSDAAHTAKWLDSSAKPSPMEYSASAEPVGVPGDKVSCDSPGACKDRFGDATGGLGAPNTYYKLNDTSPESPAKCKYCGLRFYSLGGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUF8</accession>
    <name>A4RUF8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_30605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416951.1">
        <property type="nucleotide sequence ID" value="XM_001416914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUF8"/>
    <dbReference type="GeneID" id="5000587"/>
    <dbReference type="Gramene" id="ABO95244">
        <property type="protein sequence ID" value="ABO95244"/>
        <property type="gene ID" value="OSTLU_30605"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30605"/>
    <dbReference type="eggNOG" id="ENOG502QQUV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039978_0_0_1"/>
    <dbReference type="OMA" id="TADYTTH"/>
    <dbReference type="OrthoDB" id="674948at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14704">
        <property type="entry name" value="bZIP_HY5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416:SF8">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
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        <property type="entry name" value="Leucine zipper domain"/>
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        <property type="entry name" value="BZIP"/>
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        <property type="entry name" value="BZIP_BASIC"/>
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    </dbReference>
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        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
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        <location>
            <begin position="17"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="17"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="375" mass="40919" checksum="FC7458979537EF18" modified="2007-05-15" version="1">MSARSAGKVDGNATETEAERLERLRRNRESAKNMRARKREYVRDLEKRASALEKQNGALQGMVMHLTNENHALRMNLQAATGVALPTVMVPAPYPTMTPKLPLPPLDAPIIETPPSPQLDLKKPAPKRRKKTVAASVTALALGALSVVGLAAPRSNSAGTQFSSSSRRLLAITAAPEDPLTKIGVNVTSLREEIMRNDDERTFSLPDRAVAEGIALWGDKTSDGRIVNVLKSTNVNDPWFSAFKAAGMPQHVNLLSRVSCTEVFKFKGSDEANAEPGAVATTSAWTNEQREKMERKKYSGAIPLPSGRENVTKVSEQTSLEAEDSLVSVLLPPPVEGVMQQLSKLFVVTFNKRTADYTTHSCLMPQPMTQAHHHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUX3</accession>
    <name>A4RUX3_OSTLU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_14743</name>
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    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001416707.1"/>
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        <property type="gene ID" value="OSTLU_14743"/>
    </dbReference>
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    <dbReference type="OMA" id="LALYECY"/>
    <dbReference type="OrthoDB" id="89765at2759"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Laminin_G_3"/>
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    </dbReference>
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        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1900" mass="200731" checksum="CCE6A58A3059ACF9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV11</accession>
    <name>A4RV11_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_24295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        </lineage>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV11"/>
    <dbReference type="STRING" id="436017.A4RV11"/>
    <dbReference type="GeneID" id="5000900"/>
    <dbReference type="Gramene" id="ABO95349">
        <property type="protein sequence ID" value="ABO95349"/>
        <property type="gene ID" value="OSTLU_24295"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24295"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_301574_0_0_1"/>
    <dbReference type="OrthoDB" id="498891at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06150">
        <property type="entry name" value="YjgF_YER057c_UK114_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035709">
        <property type="entry name" value="YoaB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="289"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="174"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="561"/>
        </location>
    </feature>
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        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="547"/>
            <end position="558"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="991" mass="108539" checksum="C3C250FA83029E48" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV80</accession>
    <name>A4RV80_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416796.1">
        <property type="nucleotide sequence ID" value="XM_001416759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV80"/>
    <dbReference type="GeneID" id="5001013"/>
    <dbReference type="Gramene" id="ABO95089">
        <property type="protein sequence ID" value="ABO95089"/>
        <property type="gene ID" value="OSTLU_30878"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30878"/>
    <dbReference type="HOGENOM" id="CLU_2150094_0_0_1"/>
    <dbReference type="OrthoDB" id="10641897at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="112" mass="11617" checksum="81251B0E9FF96EE3" modified="2007-05-15" version="1">MFDKDGKPRRGSAPRRGHTLPGMSDALGELRGVLQKVGVKSAAAAAEAADDPTSSGAEADGEASEVESERRAVREPVVAAPPPAKAEKPQWMVELAAKNAAKRAAQNSSDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV91</accession>
    <name>A4RV91_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417097.1">
        <property type="nucleotide sequence ID" value="XM_001417060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV91"/>
    <dbReference type="GeneID" id="5000963"/>
    <dbReference type="Gramene" id="ABO95390">
        <property type="protein sequence ID" value="ABO95390"/>
        <property type="gene ID" value="OSTLU_14827"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14827"/>
    <dbReference type="eggNOG" id="ENOG502S1N3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1186667_0_0_1"/>
    <dbReference type="OrthoDB" id="525072at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="234" mass="25934" checksum="24791087FAF5663D" modified="2007-05-15" version="1">MPPKSKKTGKKKPGKSAAASSKAKDATGATGGAKDVDKSTTKEEEEKDMTHAYADDLKTDIYTDVNANPKALVHATEWRKIMNGTTLDEEACARPSSTTTTFATGRLTDRLARAGDPVEINPSVGAGMKIMTVDEWISRWKPNERFPDCLSCGSTNTKEHHFSQTWCRGKKKFESETICCECHMWSWRSYADPDFLSPEEYDKLKWEKMVQENATRLKDARVEDAAAESVAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVA5</accession>
    <name>A4RVA5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH-ubiquinone reductase complex 1 MLRQ subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416807.1">
        <property type="nucleotide sequence ID" value="XM_001416770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVA5"/>
    <dbReference type="STRING" id="436017.A4RVA5"/>
    <dbReference type="GeneID" id="5001070"/>
    <dbReference type="Gramene" id="ABO95100">
        <property type="protein sequence ID" value="ABO95100"/>
        <property type="gene ID" value="OSTLU_30905"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30905"/>
    <dbReference type="eggNOG" id="ENOG502S1RJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167098_0_0_1"/>
    <dbReference type="OMA" id="NRAPQIM"/>
    <dbReference type="OrthoDB" id="202195at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33417">
        <property type="entry name" value="G-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11180" checksum="1AEE6961E3FC3363" modified="2007-05-15" version="1">MSTTFAQRWLRPEVYPIFAAIGGAVGLCGFFCTRQLVASPGFTAAKSRRMAGILETKADFDEGKNWRDHRVRRFLRSMYGGKGHGPQIFPGLNESFGGGQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVG8</accession>
    <name>A4RVG8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_36797</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417132.1">
        <property type="nucleotide sequence ID" value="XM_001417095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVG8"/>
    <dbReference type="STRING" id="436017.A4RVG8"/>
    <dbReference type="GeneID" id="5001667"/>
    <dbReference type="Gramene" id="ABO95425">
        <property type="protein sequence ID" value="ABO95425"/>
        <property type="gene ID" value="OSTLU_36797"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36797"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_9_7_1"/>
    <dbReference type="OMA" id="ISKWGHE"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF120">
        <property type="entry name" value="BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="73"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="275"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="465" mass="50625" checksum="6110692A1DFF86BA" modified="2007-05-15" version="1" fragment="single">MTLDALDVLDDDALNALDVDGIARAAANKRARVDVGCARVETNENVAPSADVRATLKARFGLDAFRPGQREVVEAVLAGRDACVFWSTGSGKSLPYQLAAFASGKSAVVVSPLISLMQDQVTALNNTVGRGDGKDGDVAVFLGSAQMDHGAEARVFEGAYEIVYCTPEKLTASDSFLNGLKSLAARGRLGLIAIDEAHCISAWGHDFRPSYTQLHMLRDAIPNVPIMALTATAVRHVRDDISKILRLRDPYVSVNSVDRTNLHINVVRRTDFSRDLDYIVERVRAGARVSPAIVYCPTIAEVVKVAGALKQRLGDDVVRMYHGQMSPPERHDAHMDFLTSRSPVIVATTAFGMGIDKPDVRAITLLGASKTMEEFYQQIGRAGRDGLASEVSMLFTDGDFTRYASDFYTKDLTPQARDAQAKSTNALKEFALNRETCRRVMIMKHFGETAPFVRCGGTCDNCARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVH0</accession>
    <name>A4RVH0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24349</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417134.1">
        <property type="nucleotide sequence ID" value="XM_001417097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVH0"/>
    <dbReference type="STRING" id="436017.A4RVH0"/>
    <dbReference type="GeneID" id="5001431"/>
    <dbReference type="Gramene" id="ABO95427">
        <property type="protein sequence ID" value="ABO95427"/>
        <property type="gene ID" value="OSTLU_24349"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24349"/>
    <dbReference type="eggNOG" id="ENOG502QR9H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_285507_0_0_1"/>
    <dbReference type="OMA" id="DCGPTLE"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08379">
        <property type="entry name" value="C2D_MCTP_PRT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047255">
        <property type="entry name" value="C2D_MCTP_PRT_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047259">
        <property type="entry name" value="QUIRKY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31425:SF50">
        <property type="entry name" value="FT-INTERACTING PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31425">
        <property type="entry name" value="PHOSPHORIBOSYLANTHRANILATE TRANSFERASE ISOFORM 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="699"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="845"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="109"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="290"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="435"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="743"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="979" mass="110894" checksum="54C276E01032DAA6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVH2</accession>
    <name>A4RVH2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417136.1">
        <property type="nucleotide sequence ID" value="XM_001417099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVH2"/>
    <dbReference type="GeneID" id="5001184"/>
    <dbReference type="Gramene" id="ABO95429">
        <property type="protein sequence ID" value="ABO95429"/>
        <property type="gene ID" value="OSTLU_30974"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30974"/>
    <dbReference type="HOGENOM" id="CLU_2578191_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="81" mass="8638" checksum="03D195B201781B16" modified="2007-05-15" version="1">MWSGVVATSCWCYLRVSSVSGALLLGACVFAKASFDMLVALRSSKSETTANWYVEDANEAVHTGPFVTPRYGAEDGRAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVP0</accession>
    <name>A4RVP0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_5419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417178.1">
        <property type="nucleotide sequence ID" value="XM_001417141.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVP0"/>
    <dbReference type="STRING" id="436017.A4RVP0"/>
    <dbReference type="GeneID" id="5001210"/>
    <dbReference type="Gramene" id="ABO95471">
        <property type="protein sequence ID" value="ABO95471"/>
        <property type="gene ID" value="OSTLU_5419"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5419"/>
    <dbReference type="eggNOG" id="ENOG502QT54">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058336_0_3_1"/>
    <dbReference type="OMA" id="HPHYIKT"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31208:SF11">
        <property type="entry name" value="CYTOKININ RIBOSIDE 5'-MONOPHOSPHATE PHOSPHORIBOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31208">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="223" mass="24558" checksum="63346105DCDF228F" modified="2007-05-15" version="1" fragment="single">RESPAKVQLEMSQCFALVERHGRGAVYLGSARVPETHSHYARTRELAKDIATLLDCTTWSGLGPGLMDAATRGALDAERAAAGFMILLEAGGARQETREHPYLPRECYLNTSFFSARKHGLVDAGVRSALEEKTCFVALPGGVGTLDEIFEILALLQLKRIGTSHPVPFIVMNYDGCYDGLLEFLRRDMVGYGALAENELAPHWIACDTNEQALAHLRDFYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVR0</accession>
    <name>A4RVR0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS family transporter: organic cation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_2301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417456.1">
        <property type="nucleotide sequence ID" value="XM_001417419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVR0"/>
    <dbReference type="STRING" id="436017.A4RVR0"/>
    <dbReference type="GeneID" id="5001204"/>
    <dbReference type="Gramene" id="ABO95749">
        <property type="protein sequence ID" value="ABO95749"/>
        <property type="gene ID" value="OSTLU_2301"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2301"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_33_5_1"/>
    <dbReference type="OMA" id="RIIYCTL"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009705">
        <property type="term" value="C:plant-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042631">
        <property type="term" value="P:cellular response to water deprivation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="32"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="433" mass="47140" checksum="68770E41CF8EE648" modified="2007-05-15" version="1" fragment="single">EGNERTIDELFDERIGQANHTQLAQFALSSVAWLPAAFLTLTSVFTAREVDWKCATENGCLDGDSGKLLNICAMDRELWTWVDAKSSIVSEWDLVCAHEYKVQLANSIFFVGFLMGAGILGQIADSKGRIFGLYVSTALASAGAMLGAMAGGYWTYFWCTMLRGFGCGGLGVASYVLCTEVLGIKWRAVLGISTQYFWSGGIALMAPVAYTMPKWRNFSTFCGLSGLAYVALSSKFLWESPRWYLATGKADKAHEVMTHLARGNPKFTGRLPPLKQTRVVKGLNVTAVLPYPVLRQRLVAMAYIFCVTSMVYYGLSLNVDALSGSVYMNTFISGIVEFPSHVFAQIYVDRLGRRMTLLVLMGTAAVGVFSSSMFSGSSQVFVSMIGRFGIAGSFNMIYLYTTELFPTIVRSACLGTCSLAARVGGIIAPGIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVV3</accession>
    <name>A4RVV3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Photosystem I reaction center subunit III</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">PSI-F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">psaF</name>
        <name evidence="5" type="ORF">OSTLU_31108</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast thylakoid lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PsaF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417212.1">
        <property type="nucleotide sequence ID" value="XM_001417175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVV3"/>
    <dbReference type="STRING" id="436017.A4RVV3"/>
    <dbReference type="GeneID" id="5001319"/>
    <dbReference type="Gramene" id="ABO95505">
        <property type="protein sequence ID" value="ABO95505"/>
        <property type="gene ID" value="OSTLU_31108"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31108"/>
    <dbReference type="eggNOG" id="ENOG502QTZ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098828_0_0_1"/>
    <dbReference type="OMA" id="CIGWAGR"/>
    <dbReference type="OrthoDB" id="1920411at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019904">
        <property type="term" value="F:protein domain specific binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.110:FF:000001">
        <property type="entry name" value="Photosystem I reaction center subunit III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.110">
        <property type="entry name" value="Photosystem I PsaF, reaction centre subunit III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003666">
        <property type="entry name" value="PSI_PsaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036577">
        <property type="entry name" value="PSI_PsaF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34939">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT III, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34939:SF1">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT III, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02507">
        <property type="entry name" value="PSI_PsaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81536">
        <property type="entry name" value="Subunit III of photosystem I reaction centre, PsaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="2 4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="232" mass="24530" checksum="F94E42A47EAD3391" modified="2007-05-15" version="1">MNALAQVQLSSKVTVSGLKQTARVNARTVKTAAHCSAADVTRKAASLAVAAAVAATPLVVVEEAFARDVQPYAGLTPCKTSKAFAKRQKTEIKALQKRLKKYDPESAPALALNATIEKTKTRFANYGEAGLLCGKDGLPHLIVDGNLEHLGEFAVPGLGFLYVAGWIGYAGRSYVQMNKETAAKPTQGEIIIDVPKALGLMFQAGAWPLLAGLELKNGTLTAPESEITVSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWJ8</accession>
    <name>A4RWJ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="1">PPIase</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417591.1">
        <property type="nucleotide sequence ID" value="XM_001417554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWJ8"/>
    <dbReference type="STRING" id="436017.A4RWJ8"/>
    <dbReference type="GeneID" id="5001564"/>
    <dbReference type="Gramene" id="ABO95884">
        <property type="protein sequence ID" value="ABO95884"/>
        <property type="gene ID" value="OSTLU_31361"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31361"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_11_1_1"/>
    <dbReference type="OMA" id="ITTEPAC"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044178">
        <property type="entry name" value="CYP28-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47875">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP28, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47875:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP28, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="40"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="233" mass="23990" checksum="55511F83D4EE4B15" modified="2007-05-15" version="1">MDATANVTARVYLDVGACEGAANAARALGDDGGALCATPEPFGRIVVGLYGDAAPDTVRNFLALCSNAASTPTLAGTVFHKIDKGNGYVVGGKSGSPRLGQVSALSGERFSNGDVTRASAFEGRHFRPGTVSLALESAAKDGEYGTTAQFLITTGPAPVPSLDNKNIVFGRVEQGLDVVQRLSNEKTFKPSETARAYNALANLVGDSRAGKAKAAWIKPTRALVITSCGVLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX00</accession>
    <name>A4RX00_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417666.1">
        <property type="nucleotide sequence ID" value="XM_001417629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX00"/>
    <dbReference type="STRING" id="436017.A4RX00"/>
    <dbReference type="GeneID" id="5002076"/>
    <dbReference type="Gramene" id="ABO95959">
        <property type="protein sequence ID" value="ABO95959"/>
        <property type="gene ID" value="OSTLU_94241"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94241"/>
    <dbReference type="HOGENOM" id="CLU_728425_0_0_1"/>
    <dbReference type="OrthoDB" id="8607at13792"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="380" mass="41219" checksum="F95F8A8666B9E339" modified="2007-05-15" version="1">MADDTARDGGHSTEASGGARVSAARAYADVQTPKNVKKIAWQTAGASNERVTRKSMRSATRGGAPVSTVKNVNEDAEMKDGAAPLDDAPKSKSVDAAKIEEQQDPSSAGQSSEKRKRAKARANGMAFLKADIPALAAQNPKAGGAVVSTELRISPRTLAMDKAKQSASKEPAAAPGTATMTSESKEPASAPTVVAPVLAPRTVAPKHPVDQRSLMESFMIQPENVSAAVDLAPLSSFQKMSATPSQATLGEQSAQRPKPPSSLAPVTTAAEANDVMSRLKRAMEARSRADEENKRQLESALRQKEEERKRREMEMQARKAKQADQEAREREERRLRQERLAQFRLQEEEAQRKAAMEKTATHAVGFVSDFTLLQQRQRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX26</accession>
    <name>A4RX26_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAC3/GANP/THP3 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417680.1">
        <property type="nucleotide sequence ID" value="XM_001417643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX26"/>
    <dbReference type="STRING" id="436017.A4RX26"/>
    <dbReference type="GeneID" id="5001681"/>
    <dbReference type="Gramene" id="ABO95973">
        <property type="protein sequence ID" value="ABO95973"/>
        <property type="gene ID" value="OSTLU_31543"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31543"/>
    <dbReference type="eggNOG" id="KOG1861">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_517201_0_0_1"/>
    <dbReference type="OMA" id="NWRENET"/>
    <dbReference type="OrthoDB" id="498927at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF4">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
        <location>
            <begin position="223"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
        <location>
            <begin position="369"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="527" mass="57682" checksum="25939086A5195FD8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXB1</accession>
    <name>A4RXB1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_24530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417969.1">
        <property type="nucleotide sequence ID" value="XM_001417932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXB1"/>
    <dbReference type="STRING" id="436017.A4RXB1"/>
    <dbReference type="GeneID" id="5002125"/>
    <dbReference type="Gramene" id="ABO96262">
        <property type="protein sequence ID" value="ABO96262"/>
        <property type="gene ID" value="OSTLU_24530"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24530"/>
    <dbReference type="eggNOG" id="KOG4205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1186400_0_0_1"/>
    <dbReference type="OMA" id="QNRYHDM"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="13"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="5">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="85"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="22877" checksum="E4DC7AE77757F10E" modified="2007-05-15" version="1">MGDSAAGDASAGSKIFVGGLDRTVDEGVVRNFFSQFGPVMEVLVMRDPHNHQSRGFGFITFQRDDSAKQVLQNRYHDMLGKRVEVKSAVPRGQAPPPQRGPPRSSQGYGYGQPRGGPGGAAGPGYGYSGQQYGAPQAGGAPGAYDGANPWGTLGGDAAGGQKPGYGYAGDGSKPPGGTADASSHGWTEHTAPEGYVYYYNSRTGVSQWERPMELDFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="106" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXB5</accession>
    <name>A4RXB5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_1571</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417971.1">
        <property type="nucleotide sequence ID" value="XM_001417934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXB5"/>
    <dbReference type="STRING" id="436017.A4RXB5"/>
    <dbReference type="GeneID" id="5002038"/>
    <dbReference type="Gramene" id="ABO96264">
        <property type="protein sequence ID" value="ABO96264"/>
        <property type="gene ID" value="OSTLU_1571"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1571"/>
    <dbReference type="eggNOG" id="KOG0477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_7_2_1"/>
    <dbReference type="OMA" id="WIDCKYL"/>
    <dbReference type="OrthoDB" id="496750at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF48">
        <property type="entry name" value="DNA HELICASE MCM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="7">
        <location>
            <begin position="201"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="487" mass="53325" checksum="95B8B2EDF1EB77D2" modified="2007-05-15" version="1" fragment="single">ETYPELAPGIGSIRTRHVNRMWCVEGVAVRVGSAKSLEAEQVFECVKCGHQFLIPVNVEEGSGGEPPPACPRTKPCKGKSFRSVPAARRMVRDYQEIRIQEPVGGPAGGSARAAPRALLIVLEDDLVDKVQAGDDVKMAVVVRRRWYKCAREQRCEVELVGHCVSLHVKQKQQTVERIVDDVESAAFAAFWREHESKPFYARDMILRAMCPQLFGMATPKLALMLALIGGVPRRDSSGGRVRGESHILLVGDPGMGKSQLLKYAAAVAPRAIMTTGMGSSAAGLTVAATKESGEWALEAGALVLADGGVCCIDEFDSIREAERATIHEAMEQQTLSVAKAGMVTTLRTRTTVIGATNPKGGQFDMGSNDRKPSWDRAVSAHILETHARLGAIEDDLPVAAWPFDRLRRYIAHVKNVFQPQLTSDAERLLTAYYQAQRRLEGRSVARTTIRMLESLIRLTQAHARLMYRDVATRLDATVAVCLVEASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXC1</accession>
    <name>A4RXC1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D,D-heptose 1,7-bisphosphate phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_8077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GmhB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417974.1">
        <property type="nucleotide sequence ID" value="XM_001417937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXC1"/>
    <dbReference type="STRING" id="436017.A4RXC1"/>
    <dbReference type="GeneID" id="5002041"/>
    <dbReference type="KEGG" id="olu:OSTLU_8077"/>
    <dbReference type="eggNOG" id="ENOG502S8FE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085077_1_1_1"/>
    <dbReference type="OMA" id="MSFPDEC"/>
    <dbReference type="OrthoDB" id="498051at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004446">
        <property type="entry name" value="Heptose_bisP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42891">
        <property type="entry name" value="D-GLYCERO-BETA-D-MANNO-HEPTOSE-1,7-BISPHOSPHATE 7-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42891:SF1">
        <property type="entry name" value="D-GLYCERO-BETA-D-MANNO-HEPTOSE-1,7-BISPHOSPHATE 7-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004682">
        <property type="entry name" value="GmhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="151" mass="15786" checksum="A4FB5DC1802BEC36" modified="2007-05-15" version="1" fragment="single">LLDRDGVINVDVGAPGVVDVAQFELIDGAARAVRALNDAGVPTAVVTNQTAIGKGHVSAAYVEDVVHGEMRRALREDAGATLGEIYYAHKARDEPCDRRKPAPGMVVEALAANGLADEPSRAVFIGDTVTDMQAAARAGVRRCLVCTGYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXK8</accession>
    <name>A4RXK8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_2484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417770.1">
        <property type="nucleotide sequence ID" value="XM_001417733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXK8"/>
    <dbReference type="STRING" id="436017.A4RXK8"/>
    <dbReference type="GeneID" id="5001810"/>
    <dbReference type="Gramene" id="ABO96063">
        <property type="protein sequence ID" value="ABO96063"/>
        <property type="gene ID" value="OSTLU_2484"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2484"/>
    <dbReference type="eggNOG" id="KOG0190">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025879_1_0_1"/>
    <dbReference type="OMA" id="FRSKHEP"/>
    <dbReference type="OrthoDB" id="494975at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="321"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="443" mass="51626" checksum="107C6FEBCBC19A62" modified="2007-05-15" version="1" fragment="single">EAPTDDHVLKLDASIFDNELKKSKYNFVMFYAPWDGHSKAFMPRWMSYAQSHKMAGTEMTFSLVDATKERDLDKRFEIEEYPTLILFRDGVPKRYVGDRSPQHLDKFVRRNLLKPARWLEGTDDVEVFLMGRDVTVIGFFDNKDDLDVYHHAAAEFDLDFGETKSKIATEDWKAPFPTIKMWRDFDKEPVRYPGDVRDLDAIKSWIATEMVPPIVKFENKKQLERLFMGPIAANIFVFLPEDATEAEKMSKSLESAARQLRGKVHIITVDAKETVMHDYFSLRESDGPTIRLLSHDLKYQYKGSLEAAEISNDVVHFFKEFEAKKLVPLLKSQDPLPKDGDVLQVVGKTFQSLLMDNDKHVFVWFYAPWCRTCKAMKPVWDKLATLYKDEKDIIIAKMDATKNEAKDLHVRHYPTVYYYHSGDKPRHEEYDGHMETDAFTDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY15</accession>
    <name>A4RY15_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417850.1">
        <property type="nucleotide sequence ID" value="XM_001417813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY15"/>
    <dbReference type="GeneID" id="5002005"/>
    <dbReference type="Gramene" id="ABO96143">
        <property type="protein sequence ID" value="ABO96143"/>
        <property type="gene ID" value="OSTLU_31890"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31890"/>
    <dbReference type="HOGENOM" id="CLU_2077043_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="14"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="118" mass="12945" checksum="EAB05D1022A10800" modified="2007-05-15" version="1">MRRALERRAKAQTRAALKAQAAEAKTKAKIVELEAENEALRENETKLKVKVRDLGATLKSIQRTRGGAAIAAAPVVGRRVVASPPRRSFVDAGDEMLDEIDARLHSLQTFLARAKDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY65</accession>
    <name>A4RY65_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rubredoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417876.1">
        <property type="nucleotide sequence ID" value="XM_001417839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY65"/>
    <dbReference type="GeneID" id="5001927"/>
    <dbReference type="Gramene" id="ABO96169">
        <property type="protein sequence ID" value="ABO96169"/>
        <property type="gene ID" value="OSTLU_31919"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31919"/>
    <dbReference type="eggNOG" id="ENOG502RZUV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1930345_0_0_1"/>
    <dbReference type="OMA" id="CNVGKNR"/>
    <dbReference type="OrthoDB" id="498762at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136:SF1">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="2">
        <location>
            <begin position="51"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="144" mass="15561" checksum="ED70E9732BB190CB" modified="2007-05-15" version="1">MNAGRRRDARTSFGRATTTRATRATRATTTTTTAFLNFGGNRAAAGGAVDATPYVCVDCGYVYRGGDFKKLPNSYRCPTCNVGKNRFKAQGGSSMLAQKKANKAAFRARREAASKGGKATSGREALKQKMMDAQAEKDKKRGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYA5</accession>
    <name>A4RYA5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418352.1">
        <property type="nucleotide sequence ID" value="XM_001418315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYA5"/>
    <dbReference type="GeneID" id="5002231"/>
    <dbReference type="Gramene" id="ABO96645">
        <property type="protein sequence ID" value="ABO96645"/>
        <property type="gene ID" value="OSTLU_92828"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92828"/>
    <dbReference type="eggNOG" id="ENOG502SAQ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_410140_0_0_1"/>
    <dbReference type="OMA" id="PEQHFHA"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF157">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 12 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="566" mass="62030" checksum="C4D24E9F98635A7B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYH0</accession>
    <name>A4RYH0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418165.1">
        <property type="nucleotide sequence ID" value="XM_001418128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYH0"/>
    <dbReference type="GeneID" id="5002268"/>
    <dbReference type="Gramene" id="ABO96458">
        <property type="protein sequence ID" value="ABO96458"/>
        <property type="gene ID" value="OSTLU_92857"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92857"/>
    <dbReference type="HOGENOM" id="CLU_714541_0_0_1"/>
    <dbReference type="OrthoDB" id="10496369at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd08161">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="40778" checksum="048A30223A66F42B" modified="2007-05-15" version="1">MRASWVEVSTPRRPRSSALARVVESCVAGASSDLASGDDARARVVATAVVKRGASALGAASEEFGGTAPRGLARATTARLRALGVSDAVVDECGRRFWRSSDGAEVVVPTSSVGWLTHAKAQYCAARRDGNVDAASERDGTGRATRDIAVGETLTVRAEESEGDGGSGGWVGASAVRAEEGERGDGLLRWLTTAAPAALRSKADGSVGVFALEDVAAGRTLDFSMKRVDEIVRGSPLVGEEVHGKLAKAFRRHGAAGEAALERLRRRFPFSKTYQTFPMFGAFDEITTLSAISHADEPNLAREANAPLGARFVATRDVAAGEEFTLHRGRDCILEVPGTGGFLAHYEWAVEGKEAPWERAGAGGRARGGIDYSKWDDVASSSSEDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYH1</accession>
    <name>A4RYH1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_41434</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418388.1">
        <property type="nucleotide sequence ID" value="XM_001418351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYH1"/>
    <dbReference type="STRING" id="436017.A4RYH1"/>
    <dbReference type="GeneID" id="5002263"/>
    <dbReference type="Gramene" id="ABO96681">
        <property type="protein sequence ID" value="ABO96681"/>
        <property type="gene ID" value="OSTLU_41434"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41434"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_135_7_1"/>
    <dbReference type="OMA" id="NIPIQRE"/>
    <dbReference type="OrthoDB" id="75710at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14014">
        <property type="entry name" value="STKc_PknB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24363">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24363:SF0">
        <property type="entry name" value="SERINE_THREONINE KINASE LIKE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="56"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="517" mass="56798" checksum="16A8CD90A8CA4D5A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYX4</accession>
    <name>A4RYX4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translocation protein SEC62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_87529</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418469.1">
        <property type="nucleotide sequence ID" value="XM_001418432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYX4"/>
    <dbReference type="STRING" id="436017.A4RYX4"/>
    <dbReference type="GeneID" id="5002392"/>
    <dbReference type="Gramene" id="ABO96762">
        <property type="protein sequence ID" value="ABO96762"/>
        <property type="gene ID" value="OSTLU_87529"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87529"/>
    <dbReference type="eggNOG" id="KOG2927">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_795921_0_0_1"/>
    <dbReference type="OMA" id="EQYNNTE"/>
    <dbReference type="OrthoDB" id="200187at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004728">
        <property type="entry name" value="Sec62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443:SF9">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03839">
        <property type="entry name" value="Sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="359" mass="40393" checksum="7748B149D9197090" modified="2007-05-15" version="1">MSARKERAAQEIDHLAYVLRGRDGPETRSARLGDNRFDFFRGKDFYRVLRERVDVLDEYCAVDERQRREMEADAAKRDEVNAMRIKHCGACLLQRGYIVRCEREIKHARSGRVKLVKFPHYLMRTRDQTFVEDAFYAWTYEMPMSWKSVVLSGLFAVLVVAMCLFPLAPIWFKKLILYVCVAILVTFAVIFTVRLVVFVVVWIFTGEHFWIMPNLTDDTVPINEIFSPMWAFDAEAKKIGLAQRFVSLTVGGALVYGLYSYAPETGGAVANLNRAHDSILDLFNLKDGPKSLGGGANATANATNEGNATVEIEVNATVVDDANATNATNATVIPSLDEILAEVGDVEDDEEERGTRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYZ0</accession>
    <name>A4RYZ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_41496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418247.1">
        <property type="nucleotide sequence ID" value="XM_001418210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYZ0"/>
    <dbReference type="STRING" id="436017.A4RYZ0"/>
    <dbReference type="GeneID" id="5002343"/>
    <dbReference type="Gramene" id="ABO96540">
        <property type="protein sequence ID" value="ABO96540"/>
        <property type="gene ID" value="OSTLU_41496"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41496"/>
    <dbReference type="eggNOG" id="KOG3801">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120076_1_0_1"/>
    <dbReference type="OMA" id="DAFCENR"/>
    <dbReference type="OrthoDB" id="275715at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20264">
        <property type="entry name" value="Complex1_LYR_LYRM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045297">
        <property type="entry name" value="Complex1_LYR_LYRM4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47158">
        <property type="entry name" value="OS08G0239000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47158:SF1">
        <property type="entry name" value="OS08G0239000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="1">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="89" mass="10000" checksum="7C5CAAF7EF134CB7" modified="2007-05-15" version="1">MATTATRPRALELYRALLRCGRSFNDYNVREYVKRRATESFRANAALADVDAIESALEEGARELDVARRQATVYALYGGARKPSSMDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ29</accession>
    <name>A4RZ29_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L17, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL17</name>
        <name evidence="5" type="ORF">OSTLU_32234</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418503.1">
        <property type="nucleotide sequence ID" value="XM_001418466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ29"/>
    <dbReference type="STRING" id="436017.A4RZ29"/>
    <dbReference type="GeneID" id="5002277"/>
    <dbReference type="Gramene" id="ABO96796">
        <property type="protein sequence ID" value="ABO96796"/>
        <property type="gene ID" value="OSTLU_32234"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32234"/>
    <dbReference type="eggNOG" id="KOG3353">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083987_0_1_1"/>
    <dbReference type="OMA" id="NTYETAR"/>
    <dbReference type="OrthoDB" id="10254664at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057265">
        <property type="entry name" value="Ribosomal_uL22_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_uL22_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003260">
        <property type="entry name" value="PRK04223.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593:SF10">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="20595" checksum="8A9762BBA04ABF77" modified="2007-05-15" version="1">MVKYAREPEDAEKSCKARASDLRISFKNMRETCMMLKGKKLEDAEQYLKDVLAMKRCVVFRRFCGGVGRTAQAKNEGSTNGQGRWPKKAAEAVLGLLANAKSNAETKGLDIENLSVSHIQCNKAIPQRRRTYRAHGRINPYMSNPCHVEITLSEKVEAVKREAEPVKLTRKQQARLRSGSKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ41</accession>
    <name>A4RZ41_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418510.1">
        <property type="nucleotide sequence ID" value="XM_001418473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ41"/>
    <dbReference type="STRING" id="436017.A4RZ41"/>
    <dbReference type="GeneID" id="5002595"/>
    <dbReference type="Gramene" id="ABO96803">
        <property type="protein sequence ID" value="ABO96803"/>
        <property type="gene ID" value="OSTLU_15837"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15837"/>
    <dbReference type="eggNOG" id="KOG1906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_510389_0_0_1"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="85"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="534" mass="58209" checksum="90E351B58DC22EAC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZU1</accession>
    <name>A4RZU1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_32508</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418626.1">
        <property type="nucleotide sequence ID" value="XM_001418589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZU1"/>
    <dbReference type="STRING" id="436017.A4RZU1"/>
    <dbReference type="GeneID" id="5002946"/>
    <dbReference type="Gramene" id="ABO96919">
        <property type="protein sequence ID" value="ABO96919"/>
        <property type="gene ID" value="OSTLU_32508"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32508"/>
    <dbReference type="eggNOG" id="KOG1257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011405_5_2_1"/>
    <dbReference type="OMA" id="QIVNHMV"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004473">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
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        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF68">
        <property type="entry name" value="MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="8">
        <location>
            <begin position="248"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
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        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
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        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
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        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="539" mass="58598" checksum="4B5CD0F7F1B85AA7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZZ4</accession>
    <name>A4RZZ4_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_001418846.1"/>
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        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="320" mass="35839" checksum="07DFF1DCC83F114E" modified="2007-05-15" version="1">MRAIVADGDDASEWRIQSLAGSGKAEDGGPSEGAGTDQTSIMHSDEGVANVLKTMMGDDIIVDETGRIDAEACDKRQDFESTAAATARIERPEFLAPSDDDRDPEELRKLRSLTGDQMGTLATYQQMLQNKRRARDEWRVATRLALRKLFQEASEITGAYNQRIRDLAIERENTEFAIVMFDLRRARIARRLHERHLAGDFDGKSDEEAARVREALSDVHRATEIVREYAANVEETQRLLDSATFALKAAQRAFRREVQDHPASSVHLDALQALYQRQDAIARTVEEAASKKIPVFPQRHRQSARTRSKDGAIGTMDSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0A1</accession>
    <name>A4S0A1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-(3-amino-3-carboxypropyl)histidine synthase subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_32667</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DPH1/DPH2 family. DPH2 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO97002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418672.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S0A1"/>
    <dbReference type="GeneID" id="5003026"/>
    <dbReference type="Gramene" id="ABO97002">
        <property type="protein sequence ID" value="ABO97002"/>
        <property type="gene ID" value="OSTLU_32667"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32667"/>
    <dbReference type="eggNOG" id="KOG2648">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015210_1_0_1"/>
    <dbReference type="OMA" id="QIWNENH"/>
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    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DHP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00272">
        <property type="entry name" value="DPH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF2">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01121">
        <property type="entry name" value="Diphthamide_biosynthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="517" mass="55142" checksum="4B9B29ADB235A9F9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0I2</accession>
    <name>A4S0I2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418977.1">
        <property type="nucleotide sequence ID" value="XM_001418940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0I2"/>
    <dbReference type="STRING" id="436017.A4S0I2"/>
    <dbReference type="GeneID" id="5002887"/>
    <dbReference type="Gramene" id="ABO97270">
        <property type="protein sequence ID" value="ABO97270"/>
        <property type="gene ID" value="OSTLU_32756"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32756"/>
    <dbReference type="eggNOG" id="ENOG502QVBY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_480913_0_0_1"/>
    <dbReference type="OMA" id="DQECKEM"/>
    <dbReference type="OrthoDB" id="2020015at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022227">
        <property type="entry name" value="DUF3754"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33645">
        <property type="entry name" value="AMINOPEPTIDASE (DUF3754)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33645:SF11">
        <property type="entry name" value="AMINOPEPTIDASE (DUF3754)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12576">
        <property type="entry name" value="DUF3754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="574" mass="64120" checksum="437B0ADBBE8314CD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0K7</accession>
    <name>A4S0K7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418996.1">
        <property type="nucleotide sequence ID" value="XM_001418959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0K7"/>
    <dbReference type="GeneID" id="5002836"/>
    <dbReference type="Gramene" id="ABO97289">
        <property type="protein sequence ID" value="ABO97289"/>
        <property type="gene ID" value="OSTLU_16241"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16241"/>
    <dbReference type="eggNOG" id="ENOG502SWA6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_418216_0_0_1"/>
    <dbReference type="OrthoDB" id="10494210at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="2">
        <location>
            <begin position="499"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="656" mass="72893" checksum="1BB0FB7CEDE11F7E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0L1</accession>
    <name>A4S0L1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_32784</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418758.1">
        <property type="nucleotide sequence ID" value="XM_001418721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0L1"/>
    <dbReference type="GeneID" id="5002838"/>
    <dbReference type="Gramene" id="ABO97051">
        <property type="protein sequence ID" value="ABO97051"/>
        <property type="gene ID" value="OSTLU_32784"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32784"/>
    <dbReference type="eggNOG" id="KOG2632">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036445_0_0_1"/>
    <dbReference type="OMA" id="ASYESCA"/>
    <dbReference type="OrthoDB" id="10257275at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14291">
        <property type="entry name" value="UBA1_NUB1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF1">
        <property type="entry name" value="RHOMBOID PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="9">
        <location>
            <begin position="300"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="37272" checksum="3D4A8BDFFAB4D706" modified="2007-05-15" version="1">MSAVARSAQGTPLDGAPLATTAVVIAVAISFALALAANGDFARVCASPRLAFEHPLSSYHRVWTSTFSHGSFPHALLNCLAFVPMASALERSIGTTHFAWLFATFAHAAYALSASAATALWMALGYRASYESCAIGMSGVVFALIVCETNVNDVERRSVFGLFTVSSEYYPIALLLFIQLLMPGVSFIGHAGGIAAGWLYVRGYLNFLLLKETHVEYLEKLAICAPARALASFVPSNADRGARPNAEASSTAFPAFSTVRAIPTRMSEVTRNAFAGNFPGQGRKLGGDGSTTGEMANLVRVDPRALDTLVELGFAEHAARRALQECDGDSQRAIELLTESAAHDANSDEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0M1</accession>
    <name>A4S0M1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein HIRA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HIRA3501</name>
        <name evidence="14" type="ORF">OSTLU_24854</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419001.1">
        <property type="nucleotide sequence ID" value="XM_001418964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0M1"/>
    <dbReference type="STRING" id="436017.A4S0M1"/>
    <dbReference type="GeneID" id="5003001"/>
    <dbReference type="Gramene" id="ABO97294">
        <property type="protein sequence ID" value="ABO97294"/>
        <property type="gene ID" value="OSTLU_24854"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24854"/>
    <dbReference type="eggNOG" id="KOG0973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004372_3_0_1"/>
    <dbReference type="OMA" id="RGSWDGD"/>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="13">
        <location>
            <begin position="7"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="65"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="12">
        <location>
            <begin position="602"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="467"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="878" mass="94713" checksum="66D939A1EF04D039" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Q2</accession>
    <name>A4S0Q2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419018.1">
        <property type="nucleotide sequence ID" value="XM_001418981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Q2"/>
    <dbReference type="STRING" id="436017.A4S0Q2"/>
    <dbReference type="GeneID" id="5003015"/>
    <dbReference type="Gramene" id="ABO97311">
        <property type="protein sequence ID" value="ABO97311"/>
        <property type="gene ID" value="OSTLU_93077"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93077"/>
    <dbReference type="HOGENOM" id="CLU_110422_0_0_1"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244:SF493">
        <property type="entry name" value="GALACTOSE OXIDASE, CENTRAL DOMAIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244">
        <property type="entry name" value="KELCH REPEAT DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="177" mass="18417" checksum="F5FC837F270F2180" modified="2007-05-15" version="1">MVVFGGRELATGRDANDVWEYDLRWNASAGIYDGMWTRLHEGGTGGGAKPRGRSGASACALRGNLYVFGGYGGGVGDFDDLWVFNRAAGRWSAISPVGGTRPPRRSGAATTTPHGEQGAACLVFGGNGMNDVWEFNIDTNAWSLVRDNTATTSAGGATLAPRVVVVASTLLAAAFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0T9</accession>
    <name>A4S0T9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SAT1</name>
        <name evidence="9" type="ORF">OSTLU_87889</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418797.1">
        <property type="nucleotide sequence ID" value="XM_001418760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0T9"/>
    <dbReference type="STRING" id="436017.A4S0T9"/>
    <dbReference type="GeneID" id="5002716"/>
    <dbReference type="Gramene" id="ABO97090">
        <property type="protein sequence ID" value="ABO97090"/>
        <property type="gene ID" value="OSTLU_87889"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87889"/>
    <dbReference type="eggNOG" id="KOG4750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_0_1_1"/>
    <dbReference type="OMA" id="DPACTSF"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000002">
        <property type="entry name" value="Serine acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="entry name" value="serine acetyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053376">
        <property type="entry name" value="Serine_acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041874">
        <property type="entry name" value="EPS_EpsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42811">
        <property type="entry name" value="SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00971">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine acetyltransferase N-terminal" evidence="8">
        <location>
            <begin position="116"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="374" mass="39794" checksum="C27F63A5E2C00E3D" modified="2007-05-15" version="1">MTTHARFASNAHAARAPRRPRARANPRARRQGNGGDSARRAVSDGGLDAAREAARERDVAAKWAGGASKASSSSSPSPSLVDRAKRAAGRAKTGEDASTSSGEGFEGESCLLGDGIWERLREEAKTDLEGEPALASYLYSTVLAHKSIEDVLAFVLANKLRNNVLLDSQLLELFSSQYKKYPELGKKCLADMQAVYERDPACDRYLAIVLFFKGFQAIQAQRVAHSLWLEDRKALSFLLQNRISEVFHVDIHPGAVLGQGMMMDHATGVVIGETAVVGENVSILHGVTLGGTGTSQGDRHPKVGDGVVIGANVTILGNINVGADTKIGAGSVVLDDIPEGSTAVGIPAKVINRGAPQQPSLSMDQTSYITDYFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0W8</accession>
    <name>A4S0W8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_87902</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419050.1">
        <property type="nucleotide sequence ID" value="XM_001419013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0W8"/>
    <dbReference type="STRING" id="436017.A4S0W8"/>
    <dbReference type="GeneID" id="5003383"/>
    <dbReference type="Gramene" id="ABO97343">
        <property type="protein sequence ID" value="ABO97343"/>
        <property type="gene ID" value="OSTLU_87902"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87902"/>
    <dbReference type="eggNOG" id="ENOG502RZTC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_646550_0_0_1"/>
    <dbReference type="OMA" id="RFLMAWL"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="337"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="425" mass="46816" checksum="CF99CBEC23A93B92" modified="2007-05-15" version="1" fragment="single">VRARGKISEDDQDEDDGDEEAGAGGVEGWHGAYKLWKPKPRGGVADAEAAKRLKVRELLLSRDPGLNQTLISSGTSISQLFDQDKWERHRMVDRFVVDLVSIPQSTVFLRLFRPCAVLAAYTAVVVAFPSVLKYACAYFNLALPFPNFAMQSLTLPASAHSLLGTLCGLVLVFRTNSSYARFVDGRTAWGSLIKHARDVARLAIYIPDKNLQRRLLELTTAYAYVLKTRLRSGRTRSDPTDPTAFRDIPDEAVRRCVTDPALADEVLASAKTGNRCLYTLMLISKTLKLALEKGAPREIHWKIEEAVSGMGLSGGICERIVATPIPLSFSRHSARSLIIWLITLPFVLVPSMSWMSVPTIFTLAYLILGIDEIGIQIEEPFATLPLTPLCATIERDMSIVIADIFASDDADRVARDVVAGDVVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1I1</accession>
    <name>A4S1I1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_42667</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419371.1">
        <property type="nucleotide sequence ID" value="XM_001419334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1I1"/>
    <dbReference type="STRING" id="436017.A4S1I1"/>
    <dbReference type="GeneID" id="5003255"/>
    <dbReference type="Gramene" id="ABO97664">
        <property type="protein sequence ID" value="ABO97664"/>
        <property type="gene ID" value="OSTLU_42667"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42667"/>
    <dbReference type="eggNOG" id="KOG3315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073154_2_0_1"/>
    <dbReference type="OMA" id="YMVKFDD"/>
    <dbReference type="OrthoDB" id="10254842at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="190" mass="21380" checksum="B67648915FB9884C" modified="2007-05-15" version="1">MNASTTPKTLTRGKRDVALSAYALLFSELVQYHKSRAKDTSELERALEDAGADVGRRMYEAQSFRERGPGKRENRLLPLLQFIQSSFWKNAFGRAADSLEVYDDDEYLLSDRDLLVNRFVSVPKDYGDLNCGAFAAGMVGGILRSAGFPSKVSCYYSEQAPGDASGRRTTNILMKFERETIEREKRLDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1M7</accession>
    <name>A4S1M7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419391.1">
        <property type="nucleotide sequence ID" value="XM_001419354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1M7"/>
    <dbReference type="GeneID" id="5003177"/>
    <dbReference type="Gramene" id="ABO97684">
        <property type="protein sequence ID" value="ABO97684"/>
        <property type="gene ID" value="OSTLU_33153"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33153"/>
    <dbReference type="HOGENOM" id="CLU_2310848_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="100" mass="11102" checksum="EF99E849EA4CB5A8" modified="2007-05-15" version="1">MHAPINFIMHWIRIGTGSFAARMNRIGTEHRKRAMSSSTKKWLALDAVSGETAVIMAIGAGGLLGCAYAIGQGKPHFEASKKRREEEVMRTKKTDENEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1X0</accession>
    <name>A4S1X0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419223.1">
        <property type="nucleotide sequence ID" value="XM_001419186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1X0"/>
    <dbReference type="STRING" id="436017.A4S1X0"/>
    <dbReference type="GeneID" id="5003138"/>
    <dbReference type="Gramene" id="ABO97516">
        <property type="protein sequence ID" value="ABO97516"/>
        <property type="gene ID" value="OSTLU_33249"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33249"/>
    <dbReference type="eggNOG" id="ENOG502QTF3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070206_0_0_1"/>
    <dbReference type="OMA" id="GWFPFTI"/>
    <dbReference type="OrthoDB" id="426136at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018971">
        <property type="entry name" value="DUF1997"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34131">
        <property type="entry name" value="(RAP ANNOTATION RELEASE2) GALACTOSE-BINDING LIKE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34131:SF3">
        <property type="entry name" value="(RAP ANNOTATION RELEASE2) GALACTOSE-BINDING LIKE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09366">
        <property type="entry name" value="DUF1997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="195" mass="21531" checksum="D1119DFF0021BD4A" modified="2007-05-15" version="1">MSLPASQYSTLDGESVERVSDDTFKVELSELAFLGLSLRPRLKAKVRVRDDGSGCEVRVEDMELTGSGVVEYASDAFEIVSVNNVTWCDVESEALSAEERAVVESRGGEYKELTSETSVRVYIIVPGWFPFTIKSTERTGRFVVNQVVAQVVPRFLNQLAEDYGTWSRGDDSRTASAKGMFDCDVDDSAQECEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2D0</accession>
    <name>A4S2D0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Patatin</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_88172</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Lipolytic acyl hydrolase (LAH).</text>
    </comment>
    <comment type="domain">
        <text evidence="3">The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the patatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419508.1">
        <property type="nucleotide sequence ID" value="XM_001419471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2D0"/>
    <dbReference type="GeneID" id="5003543"/>
    <dbReference type="Gramene" id="ABO97801">
        <property type="protein sequence ID" value="ABO97801"/>
        <property type="gene ID" value="OSTLU_88172"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88172"/>
    <dbReference type="eggNOG" id="KOG3773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018371_3_1_1"/>
    <dbReference type="OMA" id="CHIPLYC"/>
    <dbReference type="OrthoDB" id="197155at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07224">
        <property type="entry name" value="Pat_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033562">
        <property type="entry name" value="PLPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406:SF7">
        <property type="entry name" value="PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2 3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="49"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="83"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="206"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="335" mass="35749" checksum="9CA33D9F95E26A7F" modified="2007-05-15" version="1">MSSRAATQLTATSRASSASSRSGRRSLARASASRRVAASSSTSTATDGVGFSAAGFFFPYHVGVWEELVALKVMRSDETPCAGASAGSLVAAMHCCGLTPADGKRILMDVLADCRANGVVGRVGAVLENALRKELPSDAHERCSRGNLFISVSSPMMRDGKFALDGELVSAFESFDDLVGALLASCHIPLYCGWPARRYRGKWCVDGGWHNLTPTPPGSERSVRVCAFPLLDAWRKAEPGDGKESGDVFAQQASFWAGWGDDDARNLLVAPDAAGGKPEWDYSEAIRFALLPGSNDVLEEMIVMGRMDARRWAKSVGFDVKLAMRGAVGESKITM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2J1</accession>
    <name>A4S2J1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_4642</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419540.1">
        <property type="nucleotide sequence ID" value="XM_001419503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2J1"/>
    <dbReference type="STRING" id="436017.A4S2J1"/>
    <dbReference type="GeneID" id="5003657"/>
    <dbReference type="Gramene" id="ABO97833">
        <property type="protein sequence ID" value="ABO97833"/>
        <property type="gene ID" value="OSTLU_4642"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4642"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_1"/>
    <dbReference type="OMA" id="MIYSSTC"/>
    <dbReference type="OrthoDB" id="9402762at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF53">
        <property type="entry name" value="UDP-ARABINOSE 4-EPIMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01713">
        <property type="entry name" value="NUCEPIMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="6">
        <location>
            <begin position="12"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="347" mass="38086" checksum="5CFD2EC32469A6F9" modified="2007-05-15" version="1" fragment="single">AFAFASDRKAHALVTGGAGFIGSHCAEALLRRGYAVTTVDNMSRGNAGAVEALRRMAPKGSLRAVRGDLGVVEDVDAAFGNTNMPVDAVFHFAAIAYVGESMADPVRYYSNITTNTVNLLRVMQAKDVRKMIYSSTCATYGNVEKLPITESTPTRPINPYGKSKLYAENAIKDYALANPKFKASILRYFNVFGGDPEGVLGELPRAELREHGRISGACFDAAMKNIDKLTVMGTKHPTRDGTTIRDFVHVVDLVDAHIAVAEKNKFDNPPSLYNVGTGSGVSMREFVETCKKVTGVDIEIHYRAEPRPGDYAEVYANVDKIKHELGWEAKYTDLHESLTHAWKFRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2M7</accession>
    <name>A4S2M7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_33506</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419559.1">
        <property type="nucleotide sequence ID" value="XM_001419522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2M7"/>
    <dbReference type="STRING" id="436017.A4S2M7"/>
    <dbReference type="GeneID" id="5003558"/>
    <dbReference type="Gramene" id="ABO97852">
        <property type="protein sequence ID" value="ABO97852"/>
        <property type="gene ID" value="OSTLU_33506"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33506"/>
    <dbReference type="eggNOG" id="KOG3894">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054329_0_0_1"/>
    <dbReference type="OMA" id="CRERIEF"/>
    <dbReference type="OrthoDB" id="342981at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959:SF0">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32617" checksum="01F5687457E0AF79" modified="2007-05-15" version="1">MCAASTATVARVDDVDVGARVKETRANARANAKVATCETVRAYARTAAIALEATRTYVEEHRGRYKGASDRERDAFEAETSESIRECQRCVASARDAVENARDGGALARAPQCAAHLHGIGLILSESLNDVARAFDKVRETRFAATLERAERERQRKRAATRARYDDAGTGASGADDDGVARAVRVEGVEMRQEQVHAERQDGLEEELTQLLDEVRMAEKNVIEMSALSSLFATHVQAQAEQIESLYQDAIESSRHLDMGNVEMKKTIARKGSAQRYVALILLVATLGLLFLDWYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2N1</accession>
    <name>A4S2N1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HDA3504</name>
        <name evidence="13" type="ORF">OSTLU_33510</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419561.1">
        <property type="nucleotide sequence ID" value="XM_001419524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2N1"/>
    <dbReference type="STRING" id="436017.A4S2N1"/>
    <dbReference type="GeneID" id="5003617"/>
    <dbReference type="Gramene" id="ABO97854">
        <property type="protein sequence ID" value="ABO97854"/>
        <property type="gene ID" value="OSTLU_33510"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33510"/>
    <dbReference type="eggNOG" id="KOG1343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_438325_0_0_1"/>
    <dbReference type="OrthoDB" id="564793at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="45"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Histone deacetylase" evidence="12">
        <location>
            <begin position="203"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="460"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="624" mass="67111" checksum="DBD7A7F43A3C2E0D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2N8</accession>
    <name>A4S2N8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_8121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419782.1">
        <property type="nucleotide sequence ID" value="XM_001419745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2N8"/>
    <dbReference type="STRING" id="436017.A4S2N8"/>
    <dbReference type="GeneID" id="5003563"/>
    <dbReference type="Gramene" id="ABO98075">
        <property type="protein sequence ID" value="ABO98075"/>
        <property type="gene ID" value="OSTLU_8121"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8121"/>
    <dbReference type="eggNOG" id="KOG1944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049109_9_2_1"/>
    <dbReference type="OMA" id="FFSCTFI"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF116">
        <property type="entry name" value="MPV17-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="129" mass="14309" checksum="F576E9176F173361" modified="2007-05-15" version="1" fragment="single">EHDFERTARFFVVGAALHGPFFHVAFRALERAMGASTNAATVARKVAVGHTVLFPTYTAGFFFFMSALEGETMTAAYDRFRDKAAETFISGTCYWPFANAFNFAYVPRAGRILFLNAAGVAWNAYMSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2P0</accession>
    <name>A4S2P0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_7981</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419783.1">
        <property type="nucleotide sequence ID" value="XM_001419746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2P0"/>
    <dbReference type="STRING" id="436017.A4S2P0"/>
    <dbReference type="GeneID" id="5003772"/>
    <dbReference type="Gramene" id="ABO98076">
        <property type="protein sequence ID" value="ABO98076"/>
        <property type="gene ID" value="OSTLU_7981"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7981"/>
    <dbReference type="eggNOG" id="ENOG502RZ2D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_3_2_1"/>
    <dbReference type="OrthoDB" id="497692at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045039">
        <property type="entry name" value="NSI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626:SF4">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="116" mass="12976" checksum="587AFEE4DF4CF5AC" modified="2007-05-15" version="1" fragment="single">DFERLNALFVSVGFSSRACDKLQKAVDNSYLALWVTTTRDSRFAKEGEVVGFARATSDGTFHATVWDVVVSPAWQRHGIGQGLMERIVDKILEEDICNVGLYSENKVVGLYERLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2S4</accession>
    <name>A4S2S4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exocyst complex component Sec10-like alpha-helical bundle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419797.1">
        <property type="nucleotide sequence ID" value="XM_001419760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2S4"/>
    <dbReference type="STRING" id="436017.A4S2S4"/>
    <dbReference type="GeneID" id="5003792"/>
    <dbReference type="Gramene" id="ABO98090">
        <property type="protein sequence ID" value="ABO98090"/>
        <property type="gene ID" value="OSTLU_33550"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33550"/>
    <dbReference type="eggNOG" id="KOG3745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_385155_0_0_1"/>
    <dbReference type="OMA" id="RYLECES"/>
    <dbReference type="OrthoDB" id="125856at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="1">
        <location>
            <begin position="188"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="1">
        <location>
            <begin position="546"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="718" mass="78840" checksum="76D4AEA3603EAC3D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3E4</accession>
    <name>A4S3E4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420080.1">
        <property type="nucleotide sequence ID" value="XM_001420043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3E4"/>
    <dbReference type="GeneID" id="5004219"/>
    <dbReference type="Gramene" id="ABO98373">
        <property type="protein sequence ID" value="ABO98373"/>
        <property type="gene ID" value="OSTLU_26027"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26027"/>
    <dbReference type="HOGENOM" id="CLU_130091_0_0_1"/>
    <dbReference type="OMA" id="FRRFARW"/>
    <dbReference type="OrthoDB" id="10497070at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="140" mass="16244" checksum="3DE8400695101F6C" modified="2007-05-15" version="1">MRERWRRTFSKKLAFAELYSNKFEVVKFFIRFYGAPFAAMFVLACCSSYAACMCVSVFGMIGFVLFAKLVGAGDWALSALDFMKDGFQYLTGIQGSFFASLSALVMYRTTYYTLPVVLFAYEELYYFAARFRRFARWLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3H2</accession>
    <name>A4S3H2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26054</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419916.1">
        <property type="nucleotide sequence ID" value="XM_001419879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3H2"/>
    <dbReference type="GeneID" id="5004051"/>
    <dbReference type="Gramene" id="ABO98209">
        <property type="protein sequence ID" value="ABO98209"/>
        <property type="gene ID" value="OSTLU_26054"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26054"/>
    <dbReference type="eggNOG" id="ENOG502QRSW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061819_0_0_1"/>
    <dbReference type="OMA" id="AMACARE"/>
    <dbReference type="OrthoDB" id="566807at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052751">
        <property type="term" value="F:GDP-mannose hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055295">
        <property type="entry name" value="NUDT22/NUDT9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31835">
        <property type="entry name" value="URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31835:SF1">
        <property type="entry name" value="URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="139"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="316" mass="33919" checksum="C4C5EEE93908B8F3" modified="2007-05-15" version="1">MSGAFQAYERVVACARGGGLRWDEIAFVARGSGERARVPARDDVEATIDATWARRGATVYDAAKFRFASATTRDADATDGAIARVECGLTDYKTLQGTNLAANWDAFAATKTSDDATTRTTSGCGRASAAIGTAARFAHYGMALGNCVCLRASDGKFLALRRSRDVGEAPGALVFPGGHPEPKDVGFDGDTDAMDVSRYMFESALSELREELGVDEERVRRLRCLGVTLRVVNARPCVVFYARTALSSDEILRDFYPNAEHAFESTRAVALAIDEFDRSAMPGDHVGALDFVAVALAHDDGAVALADDDPPWRRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3I6</accession>
    <name>A4S3I6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420102.1">
        <property type="nucleotide sequence ID" value="XM_001420065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3I6"/>
    <dbReference type="STRING" id="436017.A4S3I6"/>
    <dbReference type="GeneID" id="5004257"/>
    <dbReference type="Gramene" id="ABO98395">
        <property type="protein sequence ID" value="ABO98395"/>
        <property type="gene ID" value="OSTLU_26067"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26067"/>
    <dbReference type="eggNOG" id="ENOG502SXRS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1221416_0_0_1"/>
    <dbReference type="OMA" id="THPGFNN"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF14">
        <property type="entry name" value="CYTOCHROME B5 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="30"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="227" mass="25086" checksum="64DAE585EF29BA4F" modified="2007-05-15" version="1">MHASGRDVAVDLAVVDALRRAPTDDERARWRKYTREDVAAHARLADGWIVVRERVFDITAFATTHPGFNNAGQVSTALAIARALGKEASDEFEEIHSARAWTQLRDFQIGVVTREGDAEAEAEAEAETEAETERETTTRASPVPAWLAKDRDFWVKYAGGASEGVLRYLEANGCPQGRSEEDVVAEVALSTRDAASDKGEKPRRGRWWRRIVGGAIVAATFRITTKF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-04-05" modified="2025-02-05" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3S3</accession>
    <name>RTCB_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-splicing ligase RtcB homolog</fullName>
            <ecNumber evidence="1">6.5.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">3'-phosphate/5'-hydroxy nucleic acid ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ORF">OSTLU_25152</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:68080"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Catalytic component of the tRNA-splicing ligase complex.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RtcB family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419969.1">
        <property type="nucleotide sequence ID" value="XM_001419932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3S3"/>
    <dbReference type="SMR" id="A4S3S3"/>
    <dbReference type="STRING" id="436017.A4S3S3"/>
    <dbReference type="EnsemblPlants" id="ABO98262">
        <property type="protein sequence ID" value="ABO98262"/>
        <property type="gene ID" value="OSTLU_25152"/>
    </dbReference>
    <dbReference type="GeneID" id="5004154"/>
    <dbReference type="Gramene" id="ABO98262">
        <property type="protein sequence ID" value="ABO98262"/>
        <property type="gene ID" value="OSTLU_25152"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25152"/>
    <dbReference type="eggNOG" id="KOG3833">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022279_0_0_1"/>
    <dbReference type="OMA" id="QTRGVEC"/>
    <dbReference type="OrthoDB" id="10249697at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072669">
        <property type="term" value="C:tRNA-splicing ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170057">
        <property type="term" value="F:RNA ligase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1860.10:FF:000001">
        <property type="entry name" value="tRNA-splicing ligase RtcB homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="entry name" value="tRNA-splicing ligase RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03144">
        <property type="entry name" value="RtcB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027513">
        <property type="entry name" value="RtcB_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118:SF1">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="Hypothetical protein PH1602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000407236" description="RNA-splicing ligase RtcB homolog">
        <location>
            <begin position="1"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="235"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="362"/>
            <end position="363"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="411"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="437"/>
            <end position="440"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="513"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03144"/>
        </source>
    </evidence>
    <sequence length="514" mass="55852" checksum="E9E8AEFB5D557620" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3V6</accession>
    <name>A4S3V6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease M5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420160.1">
        <property type="nucleotide sequence ID" value="XM_001420123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3V6"/>
    <dbReference type="STRING" id="436017.A4S3V6"/>
    <dbReference type="GeneID" id="5004026"/>
    <dbReference type="Gramene" id="ABO98453">
        <property type="protein sequence ID" value="ABO98453"/>
        <property type="gene ID" value="OSTLU_26186"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26186"/>
    <dbReference type="eggNOG" id="ENOG502SCQP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077582_0_0_1"/>
    <dbReference type="OMA" id="YLGVGEC"/>
    <dbReference type="OrthoDB" id="536870at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043822">
        <property type="term" value="F:ribonuclease M5 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025156">
        <property type="entry name" value="RNase_M5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39156:SF2">
        <property type="entry name" value="DNA PRIMASE (BACTERIAL TYPE) AND SMALL PRIMASE-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39156">
        <property type="entry name" value="RIBONUCLEASE M5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13331">
        <property type="entry name" value="DUF4093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110455">
        <property type="entry name" value="Toprim domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease M5 C-terminal" evidence="1">
        <location>
            <begin position="69"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="215" mass="23907" checksum="4E05F44262DCF699" modified="2007-05-15" version="1">MEVKRERMDEIEELSVKYDAPIVVLFDCDTAGRQLRNAFLRRFPDAAHAFMGTRVSSAKEDGKWHARGNVGVEHGEGEDIARAIADARRADRDRAVFTREALAEWGLVADADADADVWADFGGVVQRRRLVGEYLGVGDCDGRQLLRQMNLFFTEDEAREAIEALPKRGEPVPPKMTDGRADRARAGARDLDDFTALGFDPTAYVPPGRAPRGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S491</accession>
    <name>A4S491_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exostosin GT47 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420390.1">
        <property type="nucleotide sequence ID" value="XM_001420353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S491"/>
    <dbReference type="STRING" id="436017.A4S491"/>
    <dbReference type="CAZy" id="GT47">
        <property type="family name" value="Glycosyltransferase Family 47"/>
    </dbReference>
    <dbReference type="GeneID" id="5004275"/>
    <dbReference type="Gramene" id="ABO98683">
        <property type="protein sequence ID" value="ABO98683"/>
        <property type="gene ID" value="OSTLU_26328"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26328"/>
    <dbReference type="eggNOG" id="KOG1021">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_557120_0_0_1"/>
    <dbReference type="OMA" id="WLFDWSK"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Exostosin GT47" evidence="5">
        <location>
            <begin position="341"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="517" mass="58168" checksum="765637F2512D506C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S499</accession>
    <name>A4S499_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Imidazole glycerol phosphate synthase hisHF</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">Glutaminase</fullName>
                <ecNumber evidence="12">3.5.1.2</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">Cyclase</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_26336</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Plastid</location>
            <location evidence="12">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">In the C-terminal section; belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="12"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420394.1">
        <property type="nucleotide sequence ID" value="XM_001420357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S499"/>
    <dbReference type="STRING" id="436017.A4S499"/>
    <dbReference type="GeneID" id="5004539"/>
    <dbReference type="Gramene" id="ABO98687">
        <property type="protein sequence ID" value="ABO98687"/>
        <property type="gene ID" value="OSTLU_26336"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26336"/>
    <dbReference type="eggNOG" id="KOG0623">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037550_0_0_1"/>
    <dbReference type="OMA" id="GNYGHFV"/>
    <dbReference type="OrthoDB" id="10254903at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000094">
        <property type="entry name" value="Imidazole glycerol phosphate synthase hisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000036">
        <property type="entry name" value="Imidazole glycerol phosphate synthase hisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050064">
        <property type="entry name" value="IGPS_HisA/HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014640">
        <property type="entry name" value="IGPS_HisHF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235:SF2">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H IGP SYNTHASE SUBUNIT HISF/H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036936">
        <property type="entry name" value="IGPS_HisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51274">
        <property type="entry name" value="GATASE_COBBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 12 15" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="16">
        <location>
            <begin position="63"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="405"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="443"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="515"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="541"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="564"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="510"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR036936-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR036936-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO98687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="590" mass="63124" checksum="2F355322EA9A74BA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4G6</accession>
    <name>A4S4G6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_26405</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420432.1">
        <property type="nucleotide sequence ID" value="XM_001420395.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S4G6"/>
    <dbReference type="GeneID" id="5004462"/>
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        <property type="protein sequence ID" value="ABO98725"/>
        <property type="gene ID" value="OSTLU_26405"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26405"/>
    <dbReference type="eggNOG" id="KOG0090">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_913340_0_0_1"/>
    <dbReference type="OMA" id="RTSMEPN"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0519">Myristate</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="33173" checksum="51F89063AFA0D9D9" modified="2007-05-15" version="1">MDVAALTARAVDAYNTSHTFARDVLSHRLAVDDANAAHALVAIVTLLAIVVAFRVVFGVGGAFAALASGPGSRSKTYKPAVLLLGGKGCGKTALWQGLKYGEQRFRTTTSVEANECGDAVVVGKNSRGREVTKSHVRVVDVPGHAKLRKEALRELARARAVVFVVDSVSFASERKEVAKFLFDILSDESFQTRKIPLMIACNKCEKLTAHPPDFIRKRLEREIDAARAADAGSLPEMAITAAQRRANAVAKKKRDKYRTLCQRPGETFTFDAFTKASRRPGVVCDRVSAMKNQLAPLCDFIVRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4H9</accession>
    <name>A4S4H9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TRP-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TPR5a</name>
        <name evidence="4" type="ORF">OSTLU_43955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_43955"/>
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        <property type="entry name" value="OUTER ENVELOPE PROTEIN 61-LIKE"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="431"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="190"/>
        </location>
    </feature>
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            <end position="247"/>
        </location>
    </feature>
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            <end position="243"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="453" mass="49376" checksum="EFC95F53AA122359" modified="2007-05-15" version="1" fragment="single">AQQMMSNMTPEQMAQMQRMAGSMGLGAPPGAAEAMKNMTAEDMRRAAQEMGNMTPEQLKTQYEQAQGHAKASADYRYAGSETLKKEGNKLVGEGKHADAVEKYARVKENLKDDVNAAAKTLRLSCMLNMALCFNKIGKHDGAISECTEALELEPRSLKAYYRRGQAYVAKGELEQGVNDLMRANKLSPGDETVAGELEAAVKRMESQGLAVPAAAPEFDHPEAAPTTSAGSSGSAMPGMPGMPTLTPDVQAQQMSSMMGNLSDDQIEQMAATNPMMAGMDPDHVKKAAGMMKNMKPETMQSMMKMAQSMGTEGGKGFDPNDPEMMSKMQKELNNPEMREAMVEMIQGMDSESLKEMSKSMGMTMDDAQAEQAVNALKNISPKTMERMLSMASVAGGIYSRFKRPIDWAMRNKRTALSIFVVFTAMGTTYVLRWWRRRGGAVEAADNQTSTSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4R4</accession>
    <name>A4S4R4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA polymerase eta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_44217</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UmuC"/>
    </dbReference>
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        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873:SF1">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21704">
        <property type="entry name" value="POLH-Rev1_HhH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036603">
        <property type="entry name" value="DPol_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="281"/>
        </location>
    </feature>
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        <location>
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            <end position="412"/>
        </location>
    </feature>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00044975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="534" mass="58373" checksum="1422BF6AB51E0F56" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4T3</accession>
    <name>A4S4T3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420454.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S4T3"/>
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    <dbReference type="Gramene" id="ABO98784">
        <property type="protein sequence ID" value="ABO98784"/>
        <property type="gene ID" value="OSTLU_26520"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26520"/>
    <dbReference type="HOGENOM" id="CLU_055690_6_0_1"/>
    <dbReference type="OMA" id="VGEWCPK"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21496:SF23">
        <property type="entry name" value="3-PHENYLPROPIONATE_CINNAMIC ACID DIOXYGENASE FERREDOXIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21496">
        <property type="entry name" value="FERREDOXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="32"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="150" mass="15691" checksum="E0036497F1386AFB" modified="2007-05-15" version="1">MSISTRARATPTLGRRARATRTNALRDTGVTRDGLRAAEKQRVVVDVDGVGKVLLQEFANDVYAVSNKCPHLGLSLQGKTPLLSATVSDGAIACPAHGSAFDLKTGEARGEWCPKLPALPVVGKKYCGEPTAIASYAVSVDESGAIKIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Z5</accession>
    <name>A4S4Z5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DM10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_26583</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420520.1">
        <property type="nucleotide sequence ID" value="XM_001420483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Z5"/>
    <dbReference type="STRING" id="436017.A4S4Z5"/>
    <dbReference type="GeneID" id="5004534"/>
    <dbReference type="Gramene" id="ABO98813">
        <property type="protein sequence ID" value="ABO98813"/>
        <property type="gene ID" value="OSTLU_26583"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26583"/>
    <dbReference type="eggNOG" id="KOG0888">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060216_3_1_1"/>
    <dbReference type="OMA" id="VCMCLEI"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006602">
        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43109">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43109:SF2">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51336">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM10" evidence="9">
        <location>
            <begin position="3"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="352" mass="39126" checksum="975087C7281B0C97" modified="2007-05-15" version="1">MRTESRLGFQAVWVDPAQDFERAFTLFYYPEDGDVELIEDKRKKAFLRKCAPETPIALDELFIGATVTIWSRRLTVRGYADERTATAMKTKREESFALVSSENVCRIGRIVHAMQENGLTIAEMKTVAFGTSRLEELETALPRNARALASGTSCAIRAIGCEANAILARLFAHTNDVVRSMDEEHARALGELATGSSSKSPTEHSSLVVVKPSGMAHLGAILDFLCEKKGLDLIQARTLALTRLEAEAFYAVYVDVLDKEEVKMMIDELSCGACVALQLSRLRSPETLVDDIREIVGPRDPEIARVLRPESLRARFGEDKQRNAVHCADLTEDGELEVDFMFNLPRRTSVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5A1</accession>
    <name>A4S5A1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MC family transporter: adenylate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_26689</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420738.1">
        <property type="nucleotide sequence ID" value="XM_001420701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5A1"/>
    <dbReference type="GeneID" id="5004807"/>
    <dbReference type="Gramene" id="ABO99031">
        <property type="protein sequence ID" value="ABO99031"/>
        <property type="gene ID" value="OSTLU_26689"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26689"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_10_3_1"/>
    <dbReference type="OMA" id="FFAYECA"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="23"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="121"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="221"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="308" mass="31872" checksum="EFE1EF5AFA34734E" modified="2007-05-15" version="1">MARSRVVDAPSSTSRDDAPSSTTNASARFVAGCASGAVSRIATQPLEVRRLRVMTGRGSNESTSLRAIYRTEGASALFAGTKASVARHAPAKGLNFLVFGAVKEALRRARAAAGTSTSNAARASDALISGAVAGLSSLALLYPLDSLLVRQATGGPSAATLGLGRGLRKIFRDEGARGLYRGALPAAIAVVPEAAITFGSYDLMRDWYGRRAKSAARSAAAAAAPSLAFGMISAACGQAVSFPLDVVSRRMVVERGGFLAVARALFRDRGLRGFYAGLRATTVKTIPMSSLSFFAYECAMRALAPGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5L7</accession>
    <name>A4S5L7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="3">1.1.1.271</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_26810</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="3"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420794.1">
        <property type="nucleotide sequence ID" value="XM_001420757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5L7"/>
    <dbReference type="STRING" id="436017.A4S5L7"/>
    <dbReference type="GeneID" id="5004630"/>
    <dbReference type="Gramene" id="ABO99087">
        <property type="protein sequence ID" value="ABO99087"/>
        <property type="gene ID" value="OSTLU_26810"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26810"/>
    <dbReference type="eggNOG" id="KOG1431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_18_2_1"/>
    <dbReference type="OMA" id="HPSNYGY"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238:SF1">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="36026" checksum="19CC5872AFFE160B" modified="2007-05-15" version="1">MTKKVVLVTGGSGLVGSAIREVIAGERPENEEWIFASSKDADLCDPASTAAMFEKYKPTHVIHLAAQVGGLFANMKYKVEFWRNNIAMNDNIFQECHKRGVEKLVSCLSTCIFPDKTTFPIDETMIHDGPPHFSNEGYAYAKRMVDVQNRMYKAQHGCNFTAVIPTNIFGKHDNFHLDNSHVIPGLIHRGYLCKQKGEPFTIWGSGTPLRQFIYSNDLARLMIWTMREYQEADPIILSVGEEDEISIADVARSVAKALDFQGEVNFDTTKADGQFKKTANNAKLRKYLPDFKFTPFDEAMASTVKWFMENYETPGAVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Q1</accession>
    <name>A4S5Q1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420811.1">
        <property type="nucleotide sequence ID" value="XM_001420774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Q1"/>
    <dbReference type="GeneID" id="5004910"/>
    <dbReference type="Gramene" id="ABO99104">
        <property type="protein sequence ID" value="ABO99104"/>
        <property type="gene ID" value="OSTLU_93538"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93538"/>
    <dbReference type="eggNOG" id="ENOG502QQRI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1055953_0_0_1"/>
    <dbReference type="OMA" id="DENCWIW"/>
    <dbReference type="OrthoDB" id="354304at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47580">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47580:SF1">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="28924" checksum="B6ABC1A1F786E884" modified="2007-05-15" version="1" fragment="single">VGAVGAGEIGAAPARAFIDLPSRLHNRYFFVRHGESVLDVRNGGMILSNPSFKYDTTFGLTARGRAQMQEAAKTILRDFDGAPAWLYTSNFQRSFQSALVLREEIGLLFSQMRTEFSGLLDPRKMGALDFGSQEAWVDVWKNDFDDPSSTPPPVPSSLQPSASVESCLDIYRRALEAFTRLEATYYGEDIIIVSHQDTLSVFAAALNGTDLSRHHLDYPFELGQVRCVDLTVPPRDGSIAPTDLRGDYAVGDSAINYSSSSTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5X5</accession>
    <name>A4S5X5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_6551</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420847.1">
        <property type="nucleotide sequence ID" value="XM_001420810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5X5"/>
    <dbReference type="STRING" id="436017.A4S5X5"/>
    <dbReference type="GeneID" id="5004886"/>
    <dbReference type="Gramene" id="ABO99140">
        <property type="protein sequence ID" value="ABO99140"/>
        <property type="gene ID" value="OSTLU_6551"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6551"/>
    <dbReference type="eggNOG" id="KOG2946">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059592_3_1_1"/>
    <dbReference type="OMA" id="IKQTDIQ"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF1">
        <property type="entry name" value="PROTEIN YIPF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="7">
        <location>
            <begin position="39"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="173" mass="18316" checksum="1893E41EF7157DE7" modified="2007-05-15" version="1" fragment="single">TLDETIWATVRRDCAVVRRNCAAVLLPMNWGANGATRLREWDLWGPLAFVLTLSATLSGGAANASETFSVVFATVGLGAVALTANVLLLGGKIIFLQSVALLGYCVVPLCLASALCLASENKVYRFIVVAAAVTWSSKASVPFVSAAMPASRRALAVYPVMLMYVFLGWLCVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="106" xmlns="https://uniprot.org/uniprot">
    <accession>A4S605</accession>
    <name>A4S605_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">OSTLU_26944</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420860.1">
        <property type="nucleotide sequence ID" value="XM_001420823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S605"/>
    <dbReference type="STRING" id="436017.A4S605"/>
    <dbReference type="GeneID" id="5004722"/>
    <dbReference type="Gramene" id="ABO99153">
        <property type="protein sequence ID" value="ABO99153"/>
        <property type="gene ID" value="OSTLU_26944"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26944"/>
    <dbReference type="eggNOG" id="KOG1131">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011312_1_0_1"/>
    <dbReference type="OMA" id="WQTMGIL"/>
    <dbReference type="OrthoDB" id="272481at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000135">
        <property type="entry name" value="DNA repair helicase RAD3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000128">
        <property type="entry name" value="Putative DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="7"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABO99153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="788" mass="88882" checksum="69B886D712C022D6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="109" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6S8</accession>
    <name>A4S6S8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_27227</name>
        <name evidence="12" type="ORF">OSTLU_36611</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001420959.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422899.1">
        <property type="nucleotide sequence ID" value="XM_001422862.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="5006957"/>
    <dbReference type="Gramene" id="ABO99289">
        <property type="protein sequence ID" value="ABO99289"/>
        <property type="gene ID" value="OSTLU_27227"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01258">
        <property type="protein sequence ID" value="ABP01258"/>
        <property type="gene ID" value="OSTLU_36611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27227"/>
    <dbReference type="KEGG" id="olu:OSTLU_36611"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="HRIGMLT"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="10">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="96"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="301"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP01258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="452" mass="49408" checksum="1696F5045F28AC36" modified="2007-05-15" version="1">MDAVRRAGDADASTSATVRDGEVFSKNLYFEHPSTTARSARATEDAMRARGVRVVRGADVPKIVTTFEEASFPAYVMDDLKERGLATPTPCQCQAWPIALSGRDLIAVAETGSGKTLAYVLPAIVHVNAQPVLEKGEGPIALVLAPTRELASQIELEVAKFAASSEIKHACVTGGVPKGPQIKALKSGGSEICVATPGRLIDFLDGGQTNLRRTSFVVLDEADRMLDMGFEPQIRRIIAQTRCDRQTLLFTATWPVEVREVAREFIRNDPVEMRVGGAGDGLLASKNVEQIVHIVEDAEAKYAKLMDILEEEMDGSSILVFVETKALVDQLTRRLRSEGWPALGLHGDKEQKERDWVLEEFRAARSPIMISTDVASRGLDVVGVKLVVNHDFPKSVEEYVHRIGRTGRAGRKGKSHTFFSILRDGKHARELAHVLRASNQSIPRALEGVVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S718</accession>
    <name>A4S718_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c oxidase Cu chaperone COX17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">coxC</name>
        <name evidence="9" type="ORF">OSTLU_43298</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421377.1">
        <property type="nucleotide sequence ID" value="XM_001421340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S718"/>
    <dbReference type="STRING" id="436017.A4S718"/>
    <dbReference type="GeneID" id="5005524"/>
    <dbReference type="Gramene" id="ABO99670">
        <property type="protein sequence ID" value="ABO99670"/>
        <property type="gene ID" value="OSTLU_43298"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43298"/>
    <dbReference type="eggNOG" id="KOG3496">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149618_1_2_1"/>
    <dbReference type="OMA" id="HKACMRK"/>
    <dbReference type="OrthoDB" id="1915887at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR607745-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="65" mass="7075" checksum="F5456AFE6B3DA1F9" modified="2007-05-15" version="1" fragment="single">PTRAMGGAASKAETKEKPKKICCACPETKRARDECVVTHGADEDGACREKIEQHLKCLRAEGFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7K5</accession>
    <name>A4S7K5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421469.1">
        <property type="nucleotide sequence ID" value="XM_001421432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7K5"/>
    <dbReference type="GeneID" id="5005338"/>
    <dbReference type="Gramene" id="ABO99762">
        <property type="protein sequence ID" value="ABO99762"/>
        <property type="gene ID" value="OSTLU_27526"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27526"/>
    <dbReference type="HOGENOM" id="CLU_2999857_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="57" mass="5884" checksum="9B3230A843FF9C35" modified="2007-05-15" version="1">MEGISASALSLQRPRKLANTQQSLLLVRFTGTPTGRRSGNADRSSGARARAEGGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Z8</accession>
    <name>A4S7Z8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_27675</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421361.1">
        <property type="nucleotide sequence ID" value="XM_001421324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Z8"/>
    <dbReference type="GeneID" id="5005259"/>
    <dbReference type="Gramene" id="ABO99654">
        <property type="protein sequence ID" value="ABO99654"/>
        <property type="gene ID" value="OSTLU_27675"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27675"/>
    <dbReference type="eggNOG" id="KOG1012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_335061_0_0_1"/>
    <dbReference type="OMA" id="GAMEWIN"/>
    <dbReference type="OrthoDB" id="568405at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21669">
        <property type="entry name" value="SMP_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052847">
        <property type="entry name" value="Ext_Synaptotagmin/KAHRP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47042">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47042:SF4">
        <property type="entry name" value="OS02G0313700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="8">
        <location>
            <begin position="108"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="469"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="807"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="481"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="807"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="828"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="843"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="852" mass="93261" checksum="6168D9D3BA45F3DC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S857</accession>
    <name>A4S857_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_89248</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421566.1">
        <property type="nucleotide sequence ID" value="XM_001421529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S857"/>
    <dbReference type="STRING" id="436017.A4S857"/>
    <dbReference type="GeneID" id="5005844"/>
    <dbReference type="Gramene" id="ABO99859">
        <property type="protein sequence ID" value="ABO99859"/>
        <property type="gene ID" value="OSTLU_89248"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89248"/>
    <dbReference type="eggNOG" id="KOG0257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_1"/>
    <dbReference type="OMA" id="IEPFHVM"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033853">
        <property type="term" value="F:aspartate-prephenate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033854">
        <property type="term" value="F:glutamate-prephenate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009095">
        <property type="term" value="P:aromatic amino acid family biosynthetic process, prephenate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000033">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="72"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="452" mass="48712" checksum="F1405B3DCAF5166C" modified="2007-05-15" version="1">MSRALAFGVAVGGRPASRAIRTRRATRGRAPRARETRAKVDQTLNERVANLQPSKTVALTDLARAMRDAGEDVIGLAAGEPDFATPRAVGDAGKAAIDAGKTKYSPNDGDAKLRNAIARKLEEENGLTYDGKTEIVLSNGAKQSVAQCVMATCGPGDEVLVPAPYWVSYPEMVRLSGAESVIVRTTADEGFLVTPEQLRKAITPRSRLLILCSPSNPSGAVYPKETLEELAKIVVEHPRLMVLSDEIYEHIVYAPAEHHSIAAMDGMWERTMVVNGFSKSFAMTGWRLGYVAAPKHFARAMSMIQSQITSGPNSISQEAALAALELGYKGGEDVAAMVRAFEQRRDFVSARLNAIQGVKLPKVDGAFYVFPDVSAFFGGNASAEGFGPVADVDELCRYILEKGQVALVPGSAFGVPECLRISYAASNATLEEALSRIERCLSLDVFTRNSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Z0</accession>
    <name>A4S8Z0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COMM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421840.1">
        <property type="nucleotide sequence ID" value="XM_001421803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Z0"/>
    <dbReference type="GeneID" id="5006016"/>
    <dbReference type="Gramene" id="ABP00134">
        <property type="protein sequence ID" value="ABP00134"/>
        <property type="gene ID" value="OSTLU_18475"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18475"/>
    <dbReference type="HOGENOM" id="CLU_1996453_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13305" checksum="320D35CD4BFEABBD" modified="2007-05-15" version="1">MGFERAVTHEKLRALLVERALERRGKWREKITSARAMPVEVLKDFDWCVRGTTGGAGAATGSISVANAPTCRFALRLRRGGASAAAAARDVHFSVGIDALDVIADKCAEARRAIETLAPGATPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9F6</accession>
    <name>A4S9F6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Xrn1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_18607</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422056.1">
        <property type="nucleotide sequence ID" value="XM_001422019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9F6"/>
    <dbReference type="STRING" id="436017.A4S9F6"/>
    <dbReference type="GeneID" id="5006096"/>
    <dbReference type="Gramene" id="ABP00350">
        <property type="protein sequence ID" value="ABP00350"/>
        <property type="gene ID" value="OSTLU_18607"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18607"/>
    <dbReference type="eggNOG" id="KOG2044">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020094_0_0_1"/>
    <dbReference type="OMA" id="SAMMGND"/>
    <dbReference type="OrthoDB" id="496718at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="711"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="711"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="722"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="780" mass="87812" checksum="135105C6D1CBF611" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="106" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9V8</accession>
    <name>A4S9V8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lhca3</name>
        <name evidence="8" type="ORF">OSTLU_47897</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422134.1">
        <property type="nucleotide sequence ID" value="XM_001422097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9V8"/>
    <dbReference type="STRING" id="436017.A4S9V8"/>
    <dbReference type="GeneID" id="5006296"/>
    <dbReference type="Gramene" id="ABP00451">
        <property type="protein sequence ID" value="ABP00451"/>
        <property type="gene ID" value="OSTLU_47897"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_47897"/>
    <dbReference type="eggNOG" id="ENOG502QT09">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057943_6_1_1"/>
    <dbReference type="OMA" id="MSKQYFL"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019904">
        <property type="term" value="F:protein domain specific binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009768">
        <property type="term" value="P:photosynthesis, light harvesting in photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009644">
        <property type="term" value="P:response to high light intensity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009645">
        <property type="term" value="P:response to low light intensity stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="281" mass="30157" checksum="9CFDD8F3454EF242" modified="2007-05-15" version="1">MFARTLNTVTLASAPARATKRCAKRATVVVRAEGETEAEAAPAPVKKAARKTDDLAPLYVLGNSDQSLSYLDGSLPGDYGFDPLGLSDPEGAGGFINPQWLAYSEVIHGRWAMLGVAGMVAPEVLGGLGIIPQETGLVWYKAGMIPAQGTYDYWANPFTIFWINAALMNFAELRRAQDYWNPGSMGKQELIGWEKMLGGSGEPAYPGGFFNIMGQGKSDMAKMRVKEIKNGRLAMMACFACGAQAVMTGEGPVKNLIDHVSDPFGHNLLVNFQNIGGVSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA12</accession>
    <name>A4SA12_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pherophorin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422160.1">
        <property type="nucleotide sequence ID" value="XM_001422123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA12"/>
    <dbReference type="STRING" id="436017.A4SA12"/>
    <dbReference type="GeneID" id="5006324"/>
    <dbReference type="Gramene" id="ABP00477">
        <property type="protein sequence ID" value="ABP00477"/>
        <property type="gene ID" value="OSTLU_28390"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28390"/>
    <dbReference type="eggNOG" id="ENOG502QQ68">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1139693_0_0_1"/>
    <dbReference type="OMA" id="KYLRWHD"/>
    <dbReference type="OrthoDB" id="507831at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673148" description="Pherophorin domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="28323" checksum="3B79BE323B154771" modified="2007-05-15" version="1">MRADASIAASRRFFVVAFALACALAGVARARAYGYDPCASSGERGIEIAGAVTIGLAFWPGGALERWDGYHPCAQRAQLAALGVGTTSFVINSAELTALRGTRADEDGLYATNASATMMSVVAYTATRVSAPRAVRLEAAEPTNANGRSGRVNALTLLVTLDGGDVKYLRWHDGGCGACGGVGDARCLSVGDGDVACSASLAGCDGTCSGSACDVDLATADALRCQLTVTVATSGTDKNDEVFVLGSQLERLSMYASSGAYASASAQSTAAVTGVTGFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA17</accession>
    <name>A4SA17_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THUMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_18762</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422269.1">
        <property type="nucleotide sequence ID" value="XM_001422232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA17"/>
    <dbReference type="GeneID" id="5006221"/>
    <dbReference type="Gramene" id="ABP00586">
        <property type="protein sequence ID" value="ABP00586"/>
        <property type="gene ID" value="OSTLU_18762"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18762"/>
    <dbReference type="eggNOG" id="KOG3943">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1477466_0_0_1"/>
    <dbReference type="OrthoDB" id="367221at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11717">
        <property type="entry name" value="THUMP_THUMPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2300.10:FF:000001">
        <property type="entry name" value="THUMP domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2300.10">
        <property type="entry name" value="THUMP superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040183">
        <property type="entry name" value="THUMPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452">
        <property type="entry name" value="THUMP DOMAIN CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452:SF10">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="30"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="20215" checksum="66EC6001CDB565E5" modified="2007-05-15" version="1">MRACTFVRASKEVVDVADVAALVKADLERARDTNVTFSRHAMRVVPVETTCFAGVDEIKEACKPLIEKHFKSGREQTFAIAFERRSNNTLHRTEVIEAIAGMIEQPPNKVNLGDPDLTIMVEIVKGVACLSVVQDYEKLCKYNLRMVAMTKEDREHAKATANGNAPAPGTKKNDEEKPAEAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA94</accession>
    <name>A4SA94_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422345.1">
        <property type="nucleotide sequence ID" value="XM_001422308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA94"/>
    <dbReference type="GeneID" id="5006339"/>
    <dbReference type="Gramene" id="ABP00662">
        <property type="protein sequence ID" value="ABP00662"/>
        <property type="gene ID" value="OSTLU_93996"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93996"/>
    <dbReference type="eggNOG" id="ENOG502T1PI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064877_0_0_1"/>
    <dbReference type="OMA" id="ENCISTH"/>
    <dbReference type="OrthoDB" id="10453971at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="31398" checksum="934C3C67C0552B8F" modified="2007-05-15" version="1" fragment="single">VCIVGQVRTLVRKDIQDHIYDAVLAPLLIGGKVHVFLHLDKKGVNVDVETELRSWFSLESLRVYDVEPHGRVGEVGCVSAGYPQVYRQRECLRDVQAYGNRSDVEFDHFILTRTDIEYYARLPPGETWYGLKRNLVLNGMVIYRDEVDGNSVGSGREVSFMTDTFTIIPREALDSFATMANAYENCISTHPPSENTCGDRWSWSECRIQMASASYQVGKLSTAAGEVYRGTIFRCEDSACLSIRRDYCQTEPCDVARRSLASSLVGSQIEFTDEYRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAC6</accession>
    <name>A4SAC6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_18847</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422412.1">
        <property type="nucleotide sequence ID" value="XM_001422375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAC6"/>
    <dbReference type="STRING" id="436017.A4SAC6"/>
    <dbReference type="GeneID" id="5006469"/>
    <dbReference type="Gramene" id="ABP00729">
        <property type="protein sequence ID" value="ABP00729"/>
        <property type="gene ID" value="OSTLU_18847"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18847"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110421_0_0_1"/>
    <dbReference type="OMA" id="CEDYDPY"/>
    <dbReference type="OrthoDB" id="497333at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="88"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="21300" checksum="0FF4318BDF13FEF5" modified="2007-05-15" version="1" fragment="single">MVRFGHRDMTASGRYPPQPKFQPFAFYSAVRLGDLEQLKLIASTDPYFLTQDNGAGAPIHFAVTYKQLDMIHWLIREVPECVNLRDSKGFTPLHRAAYLAQFDGYLEIFEYLLSEGADPAIECEDYDPYLNPGRKTPARLVDKDVEVRERIEELIEKYAHVEKRAEPHPALSDWWALYDYGLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAI5</accession>
    <name>A4SAI5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422440.1">
        <property type="nucleotide sequence ID" value="XM_001422403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAI5"/>
    <dbReference type="GeneID" id="5006497"/>
    <dbReference type="Gramene" id="ABP00757">
        <property type="protein sequence ID" value="ABP00757"/>
        <property type="gene ID" value="OSTLU_28582"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28582"/>
    <dbReference type="eggNOG" id="ENOG502QS8K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065036_0_0_1"/>
    <dbReference type="OMA" id="CPAQFCV"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909:SF2">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="31383" checksum="86606382E9F7B819" modified="2007-05-15" version="1">MSSRALALAASARLDARERSSRRPRRFCARATRCAAAKPHVVICPGLGNAGTDYDAFAALLRARGHGATIADVRRVDWLRNAAGAATPAYWRGTLRPKPTVNWYLDALANACEEATRDDDDVALILCAHSAGGWLARVFIDEHASEAIVGRIARLVTLGSPMKPAPRDVPGVVDQTRGILTYVDENCRSASELTRDLGIECVCVAGKYARGAETLDGVASAGAFALGQGYKQVCGRAAVDGDGITPVESALMDGARHVVLDDVYHTPLGADDAAGRAWYGSPAAFERWVPLALDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAN2</accession>
    <name>A4SAN2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MscS family transporter: small-conductance mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_29320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422639.1">
        <property type="nucleotide sequence ID" value="XM_001422602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAN2"/>
    <dbReference type="STRING" id="436017.A4SAN2"/>
    <dbReference type="GeneID" id="5006521"/>
    <dbReference type="Gramene" id="ABP00956">
        <property type="protein sequence ID" value="ABP00956"/>
        <property type="gene ID" value="OSTLU_29320"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29320"/>
    <dbReference type="eggNOG" id="ENOG502S8B0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_669751_0_0_1"/>
    <dbReference type="OrthoDB" id="431980at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566:SF5">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566">
        <property type="entry name" value="YNAI-RELATED MECHANOSENSITIVE ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="Mechanosensitive channel protein MscS (YggB), transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="7">
        <location>
            <begin position="221"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="411" mass="46271" checksum="A9F6C2CCF52C2108" modified="2007-05-15" version="1">MRALDEFDALRGRVRKTTTDAMRTSLQTVGDFMGRVEAKTQEDWHIEDVWVLVAWNWCIRRGREKLFEAAERAKNALNPSRTPKTFRGSFLDWFRQPMQLIQALFVLSYAFDVGCDMIDQLSTEWDIPDNIKLGFDKGSYTFATGILVVMVIQNYGPRLLGRFFPSIRYDASLQLVITRLTSAFVVVATLMLTLAAFGIPAQVLFSFGGLGGLAFGLAAKDFISNLIGGLVLAVMRPFKVGEKIYLTGGGGKYRDSKEKDVSNYKVDEIGWYQTRLIPKDGKVTTIPNGYFLGANVINTSREPNEFVGPQLRIAIPDYEGIPALTEEITTFLTNHPDVHASYKPPLCVLKKIDVDHLSVQIELFMYGDAHYGKKIWKKKRELVLIDLLRIVKKHCPNSPALPVSEVDGYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAU5</accession>
    <name>A4SAU5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29382</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN3 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CSN3"/>
    </dbReference>
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        <property type="entry name" value="PCI_dom"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF1">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="COP9_hel_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="69"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="31697" checksum="D0045151085E7015" modified="2007-05-15" version="1">MARAQSEAVITPQDACYLRVCLKLKAYDALAASDGILAAPAMDVAPALDATDFLLRCYYGGRALLALRRYPEAARWFQDALSAPATALSAIAVAAYKKYALATLLADAVADASTFSSPAKKYSTSRECDAYASLLAAAKKRDAAKELADVVERHEATYELDGNAGLVALVRDRAVAAKARSLAKTYSTLRLGDFASAIGFSDVEAAERVLYGMIVRGEIAARIDGVDGVVRFSEGDESSATIEDIAEALKRGLRAVSVLDARVREESDALSRHKKFASHALTEERRAAALAHVETES</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB89</accession>
    <name>A4SB89_OSTLU</name>
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        <recommendedName>
            <fullName evidence="2">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422576.1">
        <property type="nucleotide sequence ID" value="XM_001422539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB89"/>
    <dbReference type="STRING" id="436017.A4SB89"/>
    <dbReference type="GeneID" id="5006790"/>
    <dbReference type="Gramene" id="ABP00893">
        <property type="protein sequence ID" value="ABP00893"/>
        <property type="gene ID" value="OSTLU_25878"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25878"/>
    <dbReference type="eggNOG" id="KOG1461">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="546611at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="W2_domain"/>
    </dbReference>
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        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="2">
        <location>
            <begin position="801"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1005" mass="110417" checksum="BD39089297FD70D4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBC7</accession>
    <name>A4SBC7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rad4 beta-hairpin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_19106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422754.1">
        <property type="nucleotide sequence ID" value="XM_001422717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBC7"/>
    <dbReference type="STRING" id="436017.A4SBC7"/>
    <dbReference type="GeneID" id="5006811"/>
    <dbReference type="Gramene" id="ABP01071">
        <property type="protein sequence ID" value="ABP01071"/>
        <property type="gene ID" value="OSTLU_19106"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19106"/>
    <dbReference type="eggNOG" id="KOG2179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_429869_0_0_1"/>
    <dbReference type="OrthoDB" id="496800at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.110">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2460">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018327">
        <property type="entry name" value="BHD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018325">
        <property type="entry name" value="Rad4/PNGase_transGLS-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018326">
        <property type="entry name" value="Rad4_beta-hairpin_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018328">
        <property type="entry name" value="Rad4_beta-hairpin_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042488">
        <property type="entry name" value="Rad4_BHD3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10403">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10404">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10405">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03835">
        <property type="entry name" value="Rad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01030">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01032">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="6">
        <location>
            <begin position="318"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="7">
        <location>
            <begin position="475"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP01071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="637" mass="70498" checksum="9565900088B70D20" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQX4</accession>
    <name>A4RQX4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YdbS-like PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_9339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415465.1">
        <property type="nucleotide sequence ID" value="XM_001415428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQX4"/>
    <dbReference type="STRING" id="436017.A4RQX4"/>
    <dbReference type="GeneID" id="4999558"/>
    <dbReference type="Gramene" id="ABO93757">
        <property type="protein sequence ID" value="ABO93757"/>
        <property type="gene ID" value="OSTLU_9339"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9339"/>
    <dbReference type="eggNOG" id="ENOG502RXK0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159373_0_0_1"/>
    <dbReference type="OMA" id="WGDMVLT"/>
    <dbReference type="OrthoDB" id="3001at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="YdbS-like_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35688">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35688:SF2">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="YdbS-like PH" evidence="2">
        <location>
            <begin position="39"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="114" mass="12774" checksum="02E6DB534513A276" modified="2007-05-15" version="1" fragment="single">ETIVFEGPPARGEVVANVAMSWTLVWIPLAIQAVGRALWLKYKITDKRVSVISESPLRKERTDIPLDQIADVISVGRGIGAWGDMVVTLRNGEKVEIRSLPDFKKCEDVIREKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="116" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR24</accession>
    <name>A4RR24_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_39655</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="14"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415492.1">
        <property type="nucleotide sequence ID" value="XM_001415455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR24"/>
    <dbReference type="STRING" id="436017.A4RR24"/>
    <dbReference type="GeneID" id="4999747"/>
    <dbReference type="Gramene" id="ABO93784">
        <property type="protein sequence ID" value="ABO93784"/>
        <property type="gene ID" value="OSTLU_39655"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39655"/>
    <dbReference type="eggNOG" id="KOG0480">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_3_2_1"/>
    <dbReference type="OMA" id="RHQQTDK"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000347">
        <property type="term" value="C:THO complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="357"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="690"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00053280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO93784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="841" mass="94419" checksum="B4B2BBEE3B3E0847" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR98</accession>
    <name>A4RR98_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415534.1">
        <property type="nucleotide sequence ID" value="XM_001415497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR98"/>
    <dbReference type="GeneID" id="4999929"/>
    <dbReference type="Gramene" id="ABO93826">
        <property type="protein sequence ID" value="ABO93826"/>
        <property type="gene ID" value="OSTLU_92142"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92142"/>
    <dbReference type="HOGENOM" id="CLU_1629818_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="163" mass="17717" checksum="8C2210F8F8DE1217" modified="2007-05-15" version="1">MGAAKSKSASIVNASKPARALPRPGATPIAPYVPPDTFVQASPVDDARADDTALREMMSKLVVRTTDVSAEDYGYAPSPASAVKRREPPGTEALLKPRDVAEALERHRASAFSDAIVEEIARERRGKLDSKVLGLMMKHVRAHAYAEEEDERRPGGTLRVGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="112" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRK1</accession>
    <name>A4RRK1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-disulfide reductase (NADPH)</fullName>
            <ecNumber evidence="2">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_29046</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="2"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415584.1">
        <property type="nucleotide sequence ID" value="XM_001415547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRK1"/>
    <dbReference type="STRING" id="436017.A4RRK1"/>
    <dbReference type="GeneID" id="4999655"/>
    <dbReference type="Gramene" id="ABO93876">
        <property type="protein sequence ID" value="ABO93876"/>
        <property type="gene ID" value="OSTLU_29046"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29046"/>
    <dbReference type="eggNOG" id="KOG4716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_2_4_1"/>
    <dbReference type="OMA" id="MPTKYDL"/>
    <dbReference type="OrthoDB" id="5956163at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000190">
        <property type="entry name" value="Thioredoxin reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000004">
        <property type="entry name" value="Thioredoxin reductase 1, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006338">
        <property type="entry name" value="Thioredoxin/glutathione_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01438">
        <property type="entry name" value="TGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF8">
        <property type="entry name" value="THIOREDOXIN-DISULFIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="3 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0712">Selenocysteine</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="15">
        <location>
            <begin position="14"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="14">
        <location>
            <begin position="368"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="197"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO93876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="503" mass="54753" checksum="5EC864F3DC0BB228" modified="2007-05-15" version="1">MTETSCKGDHGHEYDVVVIGGGSGGLAAAKEAAKHGAKTMCLDFVKPSPAGTTWGLGGTCVNVGCIPKKLMHQAGILGESFSDAREYGWKLASEGHDWGKMVEQIQNHIGSLNFGYRTTLREKNVTYVNAYGRFKDKNTIIATKKNGQEQVITTDKVVVAVGGRPSYPDAPGAKECCITSDDIFSKPEAPGKTLCVGASYISLETAGFLTALGFDTAVAIRSIPLRGFDQEVAEKIVKYMGEHGTRFLRDSQPTVFEKQEDGKIKVTFENTMFGNTFEETFDTVVCAVGRDAVTEGLDLPAAGVEFNPKNGKIACVDEQTNVDNIYAIGDVLDTRQELTPVAIKAGVRLMRRVFADTPYKEKMNYDLVPTTVFTPLEYGTIGMSEELAVETYGADNVECYVSYFKPLEWTLNHEEHKGVPVRGDNACYVKLITNLADDERVVGFHYLGPNAGEVTQGYAVAMKMGATKKDFDETVGIHPTVSEEFTILEITKRSGIDPTKKGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRQ9</accession>
    <name>A4RRQ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415613.1">
        <property type="nucleotide sequence ID" value="XM_001415576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRQ9"/>
    <dbReference type="STRING" id="436017.A4RRQ9"/>
    <dbReference type="GeneID" id="4999954"/>
    <dbReference type="Gramene" id="ABO93905">
        <property type="protein sequence ID" value="ABO93905"/>
        <property type="gene ID" value="OSTLU_13918"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13918"/>
    <dbReference type="eggNOG" id="KOG2011">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004086_0_0_1"/>
    <dbReference type="OMA" id="FGWMLND"/>
    <dbReference type="OrthoDB" id="498590at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039662">
        <property type="entry name" value="Cohesin_Scc3/SA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056396">
        <property type="entry name" value="HEAT_SCC3-SA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020839">
        <property type="entry name" value="SCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013721">
        <property type="entry name" value="STAG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11199:SF0">
        <property type="entry name" value="LD34181P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11199">
        <property type="entry name" value="STROMAL ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24571">
        <property type="entry name" value="HEAT_SCC3-SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21581">
        <property type="entry name" value="SCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08514">
        <property type="entry name" value="STAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51425">
        <property type="entry name" value="SCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCD" evidence="2">
        <location>
            <begin position="286"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1109" mass="122542" checksum="99ABF50DC74E2FD7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS53</accession>
    <name>A4RS53_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416021.1">
        <property type="nucleotide sequence ID" value="XM_001415984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS53"/>
    <dbReference type="GeneID" id="4999613"/>
    <dbReference type="Gramene" id="ABO94313">
        <property type="protein sequence ID" value="ABO94313"/>
        <property type="gene ID" value="OSTLU_29248"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29248"/>
    <dbReference type="HOGENOM" id="CLU_2626415_0_0_1"/>
    <dbReference type="OrthoDB" id="1912023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050680">
        <property type="entry name" value="YpeA/RimI_acetyltransf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43420">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43420:SF47">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="78" mass="9076" checksum="76BF6965DDBB7FEB" modified="2007-05-15" version="1">MTVDEAHRRRALASLLMRAGERVAREWGFNVALLHVYEENRGAVRAYEKAGYETIRAPFRTPYDVLRGRTKLLMAKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS69</accession>
    <name>A4RS69_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BspA family leucine-rich repeat surface protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS69"/>
    <dbReference type="STRING" id="436017.A4RS69"/>
    <dbReference type="GeneID" id="4999749"/>
    <dbReference type="Gramene" id="ABO93982">
        <property type="protein sequence ID" value="ABO93982"/>
        <property type="gene ID" value="OSTLU_29265"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29265"/>
    <dbReference type="HOGENOM" id="CLU_1177075_0_0_1"/>
    <dbReference type="OrthoDB" id="198852at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="26017" checksum="1BF13CBB2973F88F" modified="2007-05-15" version="1">MRQLFKDKQSFNVDISAWNVGQVTDMFNMFSNAISFNQNIGGWDVSSVTQMYQMFHNATVFNQDISGWTVAQVQDMAYMFSEAKAFDKDITSWSNYTGSGSPVYVQMFVGATAWNAAWGRPGGLQNFDGPASVWAVDGTYTPPPPPPSPPPPSPPPPPSPPPPSPPPADVPTYGIGIMMGGGLLCVFFGYKYYRRRQKARAPAVSIKDRMDEDEEAMTKSTVEFFDKLDSGRIKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSE0</accession>
    <name>A4RSE0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_12268</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO94556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416226.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="5000086"/>
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        <property type="protein sequence ID" value="ABO94556"/>
        <property type="gene ID" value="OSTLU_12268"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12268"/>
    <dbReference type="eggNOG" id="KOG2121">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031317_2_2_1"/>
    <dbReference type="OMA" id="GTQRQMM"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:identical protein binding"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribonuclease Z"/>
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    </dbReference>
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        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNase_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018:SF2">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="311" mass="33588" checksum="56D1CCB942985E97" modified="2007-05-15" version="1">MKSNFSGAELTFLGTSSGAPSFTRNVSSVALRLENEVWLFDCGEATQHQLMRSKLKYAKITRIFITHMHGDHIFGLPGLICAISGARTAHSRSYGGSVVPLHIIGPPGIRQFIYSSITWSRSVLGMPLIVTELRQPARASGGSPAAHTEQLPIWTAYNDGNFCVRASVLRHPVPCFGYVIDECDASGRLDAEKCVEMGLPPGREYAMLKAGQSVTTKDGRVIRPEDVIGTPRPGRRLVHLGDTCDSSSMVSLAQGADSLIHESTFEAKKVSEALYKGHSTARMAGKFAAQVNARALILTHFSNRYAGGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSE6</accession>
    <name>A4RSE6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SANT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416502.1">
        <property type="nucleotide sequence ID" value="XM_001416465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSE6"/>
    <dbReference type="STRING" id="436017.A4RSE6"/>
    <dbReference type="GeneID" id="5000282"/>
    <dbReference type="Gramene" id="ABO94795">
        <property type="protein sequence ID" value="ABO94795"/>
        <property type="gene ID" value="OSTLU_24137"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24137"/>
    <dbReference type="eggNOG" id="KOG1878">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_272076_0_0_1"/>
    <dbReference type="OrthoDB" id="10258692at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47340">
        <property type="entry name" value="DUPLICATED HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47340:SF1">
        <property type="entry name" value="DUPLICATED HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="582"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="720"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="704"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="377"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="292"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1189" mass="129742" checksum="D05F79EFCBFB6F7D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSP7</accession>
    <name>A4RSP7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Orfan14</name>
        <name evidence="1" type="ORF">OSTLU_119625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416210.1">
        <property type="nucleotide sequence ID" value="XM_001416173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSP7"/>
    <dbReference type="GeneID" id="5000237"/>
    <dbReference type="Gramene" id="ABO94503">
        <property type="protein sequence ID" value="ABO94503"/>
        <property type="gene ID" value="OSTLU_119625"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119625"/>
    <dbReference type="HOGENOM" id="CLU_1743595_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="150" mass="16854" checksum="FCAF9C99797B4086" modified="2007-05-15" version="1">MISTQHAIQVFSTLRVTGAARQRTPVAVPLRLCSDYQTLQIAHISRKLVIAHLEHSAFFEFVLQYLTPTSNACQGRITPHVTAEKFCKCSLLKDTMLLSVGQHEVIGKEDPKHKQLVLLKTSCDAAATSFRLQGSISKRYKFETRPNVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSY2</accession>
    <name>A4RSY2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kin17-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Kin17</name>
        <name evidence="2" type="ORF">OSTLU_119540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416414.1">
        <property type="nucleotide sequence ID" value="XM_001416377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSY2"/>
    <dbReference type="STRING" id="436017.A4RSY2"/>
    <dbReference type="GeneID" id="5000330"/>
    <dbReference type="Gramene" id="ABO94707">
        <property type="protein sequence ID" value="ABO94707"/>
        <property type="gene ID" value="OSTLU_119540"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119540"/>
    <dbReference type="eggNOG" id="KOG2837">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030065_1_0_1"/>
    <dbReference type="OMA" id="IANKTHV"/>
    <dbReference type="OrthoDB" id="10266249at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2030">
        <property type="entry name" value="DNA/RNA-binding protein Kin17, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056767">
        <property type="entry name" value="C2H2-Znf_KIN17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019447">
        <property type="entry name" value="DNA/RNA-bd_Kin17_WH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037321">
        <property type="entry name" value="KIN17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038254">
        <property type="entry name" value="KIN17_WH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805:SF0">
        <property type="entry name" value="DNA_RNA-BINDING PROTEIN KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805">
        <property type="entry name" value="KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25095">
        <property type="entry name" value="C2H2-zf_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10357">
        <property type="entry name" value="WH_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01253">
        <property type="entry name" value="Kin17_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding protein Kin17 WH-like" evidence="1">
        <location>
            <begin position="46"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="327" mass="36581" checksum="31318A7252FB3145" modified="2007-05-15" version="1">MSAKSLSNQLKSKGLQRLRWYCQLCEKQCRDENGFKCHCSSPAHVRQLAVFAQNQKKVVDGFSSRFKTAFISELSLNHRNSRVAANKVYNELIANKTHVHMNATRWTSLTEFVHHLVAEGVCEIDETDKGIFITYLHAESKIFQGAVARKRTHEDDGSARKQEKLIERQVKRGAVPAKPEQHEPTGLKLQQTGFNMDLTRKEKLSQMEQSHLVGTIMRIYCAPGEQSKQKYIVTNVYKGMATLEGIGPFNSAKVSTDHLRTVIPAIGASIKVIRGENAGCIGSVISVDASGGSLRVLLEGSGDEMNTFSFEDVSKLDKKYSFNRDKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTK0</accession>
    <name>A4RTK0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_35995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416302.1">
        <property type="nucleotide sequence ID" value="XM_001416265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTK0"/>
    <dbReference type="STRING" id="436017.A4RTK0"/>
    <dbReference type="GeneID" id="5000291"/>
    <dbReference type="Gramene" id="ABO94595">
        <property type="protein sequence ID" value="ABO94595"/>
        <property type="gene ID" value="OSTLU_35995"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35995"/>
    <dbReference type="eggNOG" id="ENOG502QQQU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053421_0_0_1"/>
    <dbReference type="OMA" id="NIACCFS"/>
    <dbReference type="OrthoDB" id="439127at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009575">
        <property type="term" value="C:chromoplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098572">
        <property type="term" value="C:stromal side of plastid thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010206">
        <property type="term" value="P:photosystem II repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009644">
        <property type="term" value="P:response to high light intensity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009611">
        <property type="term" value="P:response to wounding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047558">
        <property type="entry name" value="TPR_END_plus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47661">
        <property type="entry name" value="PHOSPHOGLUCAN PHOSPHATASE LSF1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47661:SF3">
        <property type="entry name" value="PROTEIN CONTAINING PDZ DOMAIN, A K-BOX DOMAIN, AND A TPR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29415" checksum="9618DE608BC196CA" modified="2007-05-15" version="1">MKRAFPFHTATLPKPIELKFNRGNDGGAYVVFVPTDPIYDRFQVGDKIEAVSASFGDEIWGAESYGQVMYAIKNRNGDIYLKMTDMDGDLSALQQTEKSSAFKSERAGGNYGAGTKEQQMNNYSKKRELENQRLDMFDEAIELYNGKDFDNALIVFEEVAALEPKNYMGDDFSKTTEIYKVAQYNIACCFSKLGKADESLLALKRCMSAGWIDYRKIRTDPSLEFVQKQPEFTELMDKFDEPLINTNAIKAFKSLFGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTT9</accession>
    <name>A4RTT9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416843.1">
        <property type="nucleotide sequence ID" value="XM_001416806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTT9"/>
    <dbReference type="STRING" id="436017.A4RTT9"/>
    <dbReference type="GeneID" id="5001038"/>
    <dbReference type="Gramene" id="ABO95136">
        <property type="protein sequence ID" value="ABO95136"/>
        <property type="gene ID" value="OSTLU_92366"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92366"/>
    <dbReference type="eggNOG" id="KOG1816">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_675094_0_0_1"/>
    <dbReference type="OMA" id="MSHGFHE"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="325"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="274"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="408" mass="44970" checksum="88CDC00B1784398E" modified="2007-05-15" version="1">MFLRDAAKKLERENAREQGRLRDKIAVERAENARKEALRKQLDDEKMRARAREREQRRAEEAMMVQNEGVSYDARLFAQSSDAARRRGIRARGEDKAQLPASAAASVGANRSGRAHFCVSRGERKTHVGVLDYGSVDSGTIGLPEPVMRTLGLTGDAAREDGADADARLVRVTYAALPLGTKMTLKPRMNDFARDFVDQDVREVLERVMMGRSAATVGDEVVVASTTDPSKTYELKVTAVEPDDGFGAVSLLETDVEVELEPSEEYERVMDEIAARERRRKEEFLKAKEALAERERAKLAEQEAFETRKATLRASIAPEPSAARGTPGVVALRFSLPNGAVKTRKFDANASTIRDVFDYARSLDDAVLSMPTFELTTRAGEVVLREDGGDAPALAALDAQTFFVRASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUS3</accession>
    <name>A4RUS3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_34016</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417010.1">
        <property type="nucleotide sequence ID" value="XM_001416973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUS3"/>
    <dbReference type="STRING" id="436017.A4RUS3"/>
    <dbReference type="GeneID" id="5000613"/>
    <dbReference type="Gramene" id="ABO95303">
        <property type="protein sequence ID" value="ABO95303"/>
        <property type="gene ID" value="OSTLU_34016"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34016"/>
    <dbReference type="eggNOG" id="KOG2906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093932_3_0_1"/>
    <dbReference type="OMA" id="TISFECI"/>
    <dbReference type="OrthoDB" id="282152at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10509">
        <property type="entry name" value="Zn-ribbon_RPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672913" description="DNA-directed RNA polymerase subunit" evidence="12">
        <location>
            <begin position="22"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="13">
        <location>
            <begin position="78"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="10">
        <location>
            <begin position="5"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="120" mass="12930" checksum="853125DFC27049E6" modified="2007-05-15" version="1">MLTFCPTCANLLLLERGAADASTSGAGAGVGGAVRLRCASCPYAYDVVDGVKQRVDARKKTVDDVLGGDDAWRNVDKTSATCPGCAHDEAYFMQIQIRSADEPMSVFYKCVKCARQWREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUT3</accession>
    <name>A4RUT3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416727.1">
        <property type="nucleotide sequence ID" value="XM_001416690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUT3"/>
    <dbReference type="GeneID" id="5000890"/>
    <dbReference type="Gramene" id="ABO95020">
        <property type="protein sequence ID" value="ABO95020"/>
        <property type="gene ID" value="OSTLU_30731"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30731"/>
    <dbReference type="HOGENOM" id="CLU_366148_0_0_1"/>
    <dbReference type="OMA" id="QFRTCAR"/>
    <dbReference type="OrthoDB" id="497846at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="763" mass="81827" checksum="F3E6CECDC8423F78" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVC8</accession>
    <name>A4RVC8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417398.1">
        <property type="nucleotide sequence ID" value="XM_001417361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVC8"/>
    <dbReference type="GeneID" id="5001182"/>
    <dbReference type="Gramene" id="ABO95691">
        <property type="protein sequence ID" value="ABO95691"/>
        <property type="gene ID" value="OSTLU_30928"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30928"/>
    <dbReference type="eggNOG" id="KOG2793">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1581126_0_0_1"/>
    <dbReference type="OMA" id="YQNDEAT"/>
    <dbReference type="OrthoDB" id="545599at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="169" mass="18976" checksum="50FD796FFDD29751" modified="2007-05-15" version="1">MCEFLIDHAKRLLAGRSVVEVGAGTGLPGLVSARLGPSSVVLTDLPSELELLEKNVEVNVAQGKEADVTVRACAWGELDEWQGEVFDTVLCSDVLYHQPRNILKALANTLEVLCSKRSGVVVFAYHFRENLIHDAQFFEFIDELFDERARFDFGDVWMFEWVPKRGEAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVG2</accession>
    <name>A4RVG2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_8480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the p23/wos2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417418.1">
        <property type="nucleotide sequence ID" value="XM_001417381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVG2"/>
    <dbReference type="STRING" id="436017.A4RVG2"/>
    <dbReference type="GeneID" id="5001474"/>
    <dbReference type="Gramene" id="ABO95711">
        <property type="protein sequence ID" value="ABO95711"/>
        <property type="gene ID" value="OSTLU_8480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8480"/>
    <dbReference type="eggNOG" id="KOG3158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078883_3_1_1"/>
    <dbReference type="OMA" id="EVTINFY"/>
    <dbReference type="OrthoDB" id="1564555at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06465">
        <property type="entry name" value="p23_hB-ind1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000013">
        <property type="entry name" value="Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="127" mass="14584" checksum="4042C95388936EB7" modified="2007-05-15" version="1" fragment="single">HPRMKWCEREDKVYLTIELPDAKDAEVTIEAREFTFRATAAGATYEERIALFADVSKEKSTYAVTERQVFCVLIKEEAKWWERLLREGEKKPANLHVDFDRWADEDDDAGDIDTSGFDMQSMMGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVK6</accession>
    <name>A4RVK6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417157.1">
        <property type="nucleotide sequence ID" value="XM_001417120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVK6"/>
    <dbReference type="GeneID" id="5001414"/>
    <dbReference type="Gramene" id="ABO95450">
        <property type="protein sequence ID" value="ABO95450"/>
        <property type="gene ID" value="OSTLU_14910"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14910"/>
    <dbReference type="HOGENOM" id="CLU_1430224_0_0_1"/>
    <dbReference type="OrthoDB" id="10643719at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="190" mass="21317" checksum="186ACEBF78512777" modified="2007-05-15" version="1">MLSRQNVFRLFSNLLSSGAAKGPTAEEEIRALKEALREAHDRVETLSEDKRLAEKNARQMDSERAALASEQVAVQKTVSELGRELLETAKESWSIRSELAIKDAEIERLRKNKGEAKSSKVDAKPSNVEDAREFIFNYFATKRCDSVGMDELMRVKPSALSDMDLFAALAERITDTAYQTASHMVVVHQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVL6</accession>
    <name>A4RVL6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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                <person name="Rouze P."/>
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                <person name="Putnam N."/>
                <person name="Dupont C."/>
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                <person name="Zhou K."/>
                <person name="Otillar R."/>
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                <person name="Manuell A."/>
                <person name="Tai V."/>
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                <person name="Werner G."/>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
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                <person name="Manuell A."/>
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        <property type="protein sequence ID" value="ABO95970"/>
        <property type="gene ID" value="OSTLU_15305"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15305"/>
    <dbReference type="eggNOG" id="ENOG502SCWY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2253668_0_0_1"/>
    <dbReference type="OMA" id="TNFMQHE"/>
    <dbReference type="OrthoDB" id="190541at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd20251">
        <property type="entry name" value="Complex1_LYR_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47579">
        <property type="entry name" value="COMPLEX 1 LYR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47579:SF3">
        <property type="entry name" value="COMPLEX 1 LYR PROTEIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="112" mass="12939" checksum="A5A8DAB5BF0F888A" modified="2007-05-15" version="1">MSRALRRLARAKHDAATNPMGFLLENPLKLYRDCMRLADFLAHKQGHSRDALRATVRAPWRTHRDERDPEKIVALRENAVRGLSNYMMYEASRGAMAGTPAFAKEDEEERRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX50</accession>
    <name>A4RX50_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_92714</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417931.1">
        <property type="nucleotide sequence ID" value="XM_001417894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX50"/>
    <dbReference type="STRING" id="436017.A4RX50"/>
    <dbReference type="GeneID" id="5002045"/>
    <dbReference type="Gramene" id="ABO96224">
        <property type="protein sequence ID" value="ABO96224"/>
        <property type="gene ID" value="OSTLU_92714"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92714"/>
    <dbReference type="eggNOG" id="ENOG502QRY0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1743599_0_0_1"/>
    <dbReference type="OMA" id="METVAWP"/>
    <dbReference type="OrthoDB" id="546456at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.210">
        <property type="entry name" value="Chaperonin-like RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038052">
        <property type="entry name" value="Chaperonin_RbcX_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003435">
        <property type="entry name" value="Chaperonin_RcbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791">
        <property type="entry name" value="CHAPERONIN-LIKE RBCX PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791:SF1">
        <property type="entry name" value="RUBISCO CHAPERONE RBCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02341">
        <property type="entry name" value="RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158615">
        <property type="entry name" value="RbcX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="150" mass="17670" checksum="E1410CDBC8BC44BE" modified="2007-05-15" version="1">MRDARAPEQSFNDVDSLLMNYFTFRALKETLAQMQETDLSPGKGEYKWLYNFAASEYKNRGDEFIKKLFAEGRSDHAQRILAQRVVLLKRWRSYFNRGLGGERCQEKYEDVNLEILREQLFCSLNAEIDECVECDEATLYNKILKDSEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX69</accession>
    <name>A4RX69_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417944.1">
        <property type="nucleotide sequence ID" value="XM_001417907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX69"/>
    <dbReference type="STRING" id="436017.A4RX69"/>
    <dbReference type="GeneID" id="5001903"/>
    <dbReference type="Gramene" id="ABO96237">
        <property type="protein sequence ID" value="ABO96237"/>
        <property type="gene ID" value="OSTLU_31587"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31587"/>
    <dbReference type="eggNOG" id="ENOG502RXQI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1211513_0_0_1"/>
    <dbReference type="OMA" id="ERLICHD"/>
    <dbReference type="OrthoDB" id="2016911at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35699">
        <property type="entry name" value="F2J10.10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35699:SF1">
        <property type="entry name" value="F2J10.10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="229" mass="24307" checksum="59510E37622BC3A5" modified="2007-05-15" version="1">MRATTTARASTSRATPAASTRRVTARGFATRKRGFATRRPSTRIRDARRRADADDARSSARDDDDDDDDDRGATDGDDGLSSSFADEVARRGGARASTTRANPNPFDRDGASDAPKPPRFAPNPSAPRRADESDQLARSRALQSEGLEGFPARATELLKTGFAVFLGFGPFVAAISVVFCATYFLFGSDFIHGGEGYGAPAFVPAEVLLGEPTVDPTVPFASGDARRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX84</accession>
    <name>A4RX84_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <ecNumber evidence="4">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_31602</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417708.1">
        <property type="nucleotide sequence ID" value="XM_001417671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX84"/>
    <dbReference type="STRING" id="436017.A4RX84"/>
    <dbReference type="GeneID" id="5001816"/>
    <dbReference type="Gramene" id="ABO96001">
        <property type="protein sequence ID" value="ABO96001"/>
        <property type="gene ID" value="OSTLU_31602"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31602"/>
    <dbReference type="eggNOG" id="ENOG502QQ8M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_3_0_1"/>
    <dbReference type="OMA" id="ALCAMIT"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF15">
        <property type="entry name" value="4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0704">Schiff base</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="369" mass="39325" checksum="3681E77F8D066972" modified="2007-05-15" version="1">MPAACAQSALRAAAPSSKRVSAPSSRLRAARRASGPASARNLARAPRGVSDAGDWACPLNGCSVSDLRAKRLITAIKTPYLASGKVDLFAYDALVEQQIAGGVEGLIVGGTTGEGQLMSWDEHIMLIAHTAQRYGGKVKVIGNTGSNSTREAVHATQQGFAVGMDASLQINPYYGKTSRAGLLEHFEAVMDLGPAIVYNVPARTSQDIVPDIMFELAKHANFAGVKECEGNARIKQYTDNGVTCWTGNDDECHDARYDAGAVGVISVTSNLVPELMREMLFDGPNPELRDRLLPLMNWLFAEPNPTGINTACAMLGVAQPVFRLPYVPYAAALRAQGAEHLRAVGLDAVAGDGAIRDLSDADFTILRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXB6</accession>
    <name>A4RXB6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_38506</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417972.1">
        <property type="nucleotide sequence ID" value="XM_001417935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXB6"/>
    <dbReference type="STRING" id="436017.A4RXB6"/>
    <dbReference type="GeneID" id="5002128"/>
    <dbReference type="Gramene" id="ABO96265">
        <property type="protein sequence ID" value="ABO96265"/>
        <property type="gene ID" value="OSTLU_38506"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38506"/>
    <dbReference type="eggNOG" id="KOG0939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002173_9_2_1"/>
    <dbReference type="OMA" id="GFFTICK"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="192" mass="21569" checksum="3A08B47060518A34" modified="2007-05-15" version="1">MAEYELVSGGRQIAVTDHNRKHFVQSYAWNSMEMVHGESIEVVAQAARKGLCDVIPAELLSSLSPVDLERLVCGLPKISVEAWKKATIYEPKVTTPEEERRVEWFWEAITQFSSADQALLLHFWAAYTHLPHSGFEGLNFKVRFDEKLSTDHLPMAQTCFLTLKLPKYASAEQTAARLLHAVRTGSSGFGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXI0</accession>
    <name>A4RXI0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_38590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417755.1">
        <property type="nucleotide sequence ID" value="XM_001417718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXI0"/>
    <dbReference type="STRING" id="436017.A4RXI0"/>
    <dbReference type="GeneID" id="5001828"/>
    <dbReference type="Gramene" id="ABO96048">
        <property type="protein sequence ID" value="ABO96048"/>
        <property type="gene ID" value="OSTLU_38590"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38590"/>
    <dbReference type="eggNOG" id="KOG1763">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042870_2_0_1"/>
    <dbReference type="OMA" id="GREMFYF"/>
    <dbReference type="OrthoDB" id="278280at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032378">
        <property type="entry name" value="ZC3H15/TMA46_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681:SF0">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681">
        <property type="entry name" value="ZINC FINGER-CONTAINING PROTEIN P48ZNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16543">
        <property type="entry name" value="DFRP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="32653" checksum="71E216C9D9F5809C" modified="2007-05-15" version="1" fragment="single">MSHEDVKKEQAADARKIKDLANKDATFGMTKGAAMNRKHEVAMQRLRDMNDPTTELGKATLRAAKKKAKEQQEFLLRTKGIDVKQPELQPGVDPKTVLCEFFKHGCCAKTADKCKYSHQLDIATRQQKRSAFELPSEDSIEMWDQKKLEAVIARKHGQEANTNNETTIVCKHFLDAVEKKLYGWFWHCPGGADCKYKHKLPPGFVFKSELRERLLEEARARKTDQDILREKLIALKKSGKNTTPMTLDVYLEWKKERVDKIKATVEASREERIKNNLLTGREII</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="107" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXJ8</accession>
    <name>A4RXJ8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peroxisomal targeting signal 1 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PEX5</name>
        <name evidence="10" type="ORF">OSTLU_31719</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418009.1">
        <property type="nucleotide sequence ID" value="XM_001417972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXJ8"/>
    <dbReference type="STRING" id="436017.A4RXJ8"/>
    <dbReference type="GeneID" id="5001804"/>
    <dbReference type="Gramene" id="ABO96302">
        <property type="protein sequence ID" value="ABO96302"/>
        <property type="gene ID" value="OSTLU_31719"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31719"/>
    <dbReference type="eggNOG" id="KOG1125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021069_0_0_1"/>
    <dbReference type="OMA" id="RISLGCC"/>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005052">
        <property type="term" value="F:peroxisome matrix targeting signal-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006625">
        <property type="term" value="P:protein targeting to peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009733">
        <property type="term" value="P:response to auxin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="476"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="573"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="607"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="641"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="712" mass="79397" checksum="022356817FD86BA8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXK6</accession>
    <name>A4RXK6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31727</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417769.1">
        <property type="nucleotide sequence ID" value="XM_001417732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXK6"/>
    <dbReference type="STRING" id="436017.A4RXK6"/>
    <dbReference type="GeneID" id="5001809"/>
    <dbReference type="Gramene" id="ABO96062">
        <property type="protein sequence ID" value="ABO96062"/>
        <property type="gene ID" value="OSTLU_31727"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31727"/>
    <dbReference type="eggNOG" id="KOG0418">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_1_1"/>
    <dbReference type="OMA" id="WTHAYAG"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14270">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000037">
        <property type="entry name" value="ubiquitin-conjugating enzyme E2 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="2"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="8">
        <location>
            <begin position="149"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="192" mass="20986" checksum="AE6E2E0DD6D2D7C8" modified="2007-05-15" version="1">MADTNRIMKELREIASDVASQVKVTQHGDSLVHMKGTIAGPSETVYEGGTFHIDIQIGASYPFEPPKMKFLTKVWHPNVSSQTGAICLDVLKDQWSPALTLKTALLSCQALLAAPEPDDPQDAQVAQMYTERRGEFDETARTWTKKYATEDQKDPVVGELMEMGFSEGAVLKALTKCGGNKDRAVEELLGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXT0</accession>
    <name>A4RXT0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1421 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418047.1">
        <property type="nucleotide sequence ID" value="XM_001418010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXT0"/>
    <dbReference type="GeneID" id="5002136"/>
    <dbReference type="Gramene" id="ABO96340">
        <property type="protein sequence ID" value="ABO96340"/>
        <property type="gene ID" value="OSTLU_31804"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31804"/>
    <dbReference type="eggNOG" id="ENOG502QPU7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1126075_0_0_1"/>
    <dbReference type="OMA" id="HERGPPH"/>
    <dbReference type="OrthoDB" id="515416at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010820">
        <property type="entry name" value="DUF1421"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31805">
        <property type="entry name" value="RECEPTOR-LIKE KINASE, PUTATIVE (DUF1421)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31805:SF14">
        <property type="entry name" value="RECEPTOR-LIKE KINASE, PUTATIVE (DUF1421)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07223">
        <property type="entry name" value="DUF1421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1421" evidence="2">
        <location>
            <begin position="206"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="247" mass="26397" checksum="1A650BE7106D2AC2" modified="2007-05-15" version="1">MSAALKTLTGQVAALSERVETLSTTSERFEATEEDDGSGSYDDDYEEHYEECPPPPPPRRGDRGPTPRRHGPPPRGGHGPPPHERGPPPHERGPPPHERGPPPHERGPPPHERGPPPHRHPPPHERGPPHRGPPPPHGPPHGYGAPPPHGSPHGYGAPPPPFEQPRPESPAYPTAYPAYTPIESSPPPPPPASAVQTSGAVPLEHMIADFGNMGFSREQVLGVVGEMAATGKKIEVNSVLDKLMRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXV1</accession>
    <name>A4RXV1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_9714</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418060.1">
        <property type="nucleotide sequence ID" value="XM_001418023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXV1"/>
    <dbReference type="STRING" id="436017.A4RXV1"/>
    <dbReference type="GeneID" id="5001769"/>
    <dbReference type="Gramene" id="ABO96353">
        <property type="protein sequence ID" value="ABO96353"/>
        <property type="gene ID" value="OSTLU_9714"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9714"/>
    <dbReference type="eggNOG" id="KOG3901">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076665_4_1_1"/>
    <dbReference type="OMA" id="CERAMNV"/>
    <dbReference type="OrthoDB" id="10266074at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07978">
        <property type="entry name" value="HFD_TAF13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF5">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="76" mass="8935" checksum="DA680B63192C6487" modified="2007-05-15" version="1" fragment="single">MYGFGDAKEPDPDSIELMEDMLVDYLTNVAHRAMEVAERRGRMQTEDLLYVIRNDRKKFARVDELLEMNAKLKDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXZ1</accession>
    <name>A4RXZ1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_92797</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418080.1">
        <property type="nucleotide sequence ID" value="XM_001418043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXZ1"/>
    <dbReference type="STRING" id="436017.A4RXZ1"/>
    <dbReference type="GeneID" id="5001993"/>
    <dbReference type="Gramene" id="ABO96373">
        <property type="protein sequence ID" value="ABO96373"/>
        <property type="gene ID" value="OSTLU_92797"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92797"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_339611_0_0_1"/>
    <dbReference type="OMA" id="MFEAEAC"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044781">
        <property type="entry name" value="At5g10690-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47581">
        <property type="entry name" value="OS09G0431600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47581:SF2">
        <property type="entry name" value="OS09G0431600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="356"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="837" mass="90427" checksum="6E649A449914E62C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXZ8</accession>
    <name>A4RXZ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2 DOCK-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_31873</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DOCK family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO96135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417805.1"/>
    </dbReference>
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        <property type="gene ID" value="OSTLU_31873"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31873"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_234281_0_0_1"/>
    <dbReference type="OMA" id="RACNTPP"/>
    <dbReference type="OrthoDB" id="47328at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DHR2_DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027007">
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    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026791">
        <property type="entry name" value="DOCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043161">
        <property type="entry name" value="DOCK_C_lobe_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043162">
        <property type="entry name" value="DOCK_C_lobe_C"/>
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        <property type="entry name" value="DOCKER_dom"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR046770">
        <property type="entry name" value="DOCKER_Lobe_B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23317">
        <property type="entry name" value="DEDICATOR OF CYTOKINESIS DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23317:SF76">
        <property type="entry name" value="LD20667P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06920">
        <property type="entry name" value="DHR-2_Lobe_A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DHR-2_Lobe_B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51651">
        <property type="entry name" value="DOCKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="459"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="DOCKER" evidence="5">
        <location>
            <begin position="1484"/>
            <end position="1945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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            <end position="136"/>
        </location>
    </feature>
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            <end position="1916"/>
        </location>
    </feature>
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        <location>
            <begin position="1938"/>
            <end position="1962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1948"/>
            <end position="1960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2055" mass="222645" checksum="551D2469ABEDBEB5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY18</accession>
    <name>A4RY18_OSTLU</name>
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        <recommendedName>
            <fullName evidence="5">Coiled-coil domain-containing protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418093.1">
        <property type="nucleotide sequence ID" value="XM_001418056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY18"/>
    <dbReference type="STRING" id="436017.A4RY18"/>
    <dbReference type="GeneID" id="5002007"/>
    <dbReference type="Gramene" id="ABO96386">
        <property type="protein sequence ID" value="ABO96386"/>
        <property type="gene ID" value="OSTLU_92803"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92803"/>
    <dbReference type="eggNOG" id="KOG2129">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_951201_0_0_1"/>
    <dbReference type="OMA" id="CGDNANA"/>
    <dbReference type="OrthoDB" id="509410at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019152">
        <property type="entry name" value="DUF2046"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15276:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15276">
        <property type="entry name" value="H4 D10S170 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09755">
        <property type="entry name" value="DUF2046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32754" checksum="AFAB4D58750B70A7" modified="2007-05-15" version="1">MPDPIRTARVASGSDADAAPDGVNADASASLERALALERAKTTTLEEELRRVRSSAEKLAQTVEAEEEFLVRTLNKKLDALTHENATLTHAMRTQRVDDALERRLRTLQEEKVQMENALEREQECMMHRLTSVLENLGRENQSVSKERDRLSFETARLREEKVRMENALESEEEHIVNLLQGQISLLLKRNRALERQVRALGGMVSDSDYVSDDPVMSPKRASGQFAFGSARDAFANRKTRPAGSSVPTSPFESDRSMSPSRRGVEARRTSNASARSISSESRSPRTSVDRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY32</accession>
    <name>A4RY32_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate/glutamate/uridylate kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_92808</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417859.1">
        <property type="nucleotide sequence ID" value="XM_001417822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY32"/>
    <dbReference type="STRING" id="436017.A4RY32"/>
    <dbReference type="GeneID" id="5002091"/>
    <dbReference type="Gramene" id="ABO96152">
        <property type="protein sequence ID" value="ABO96152"/>
        <property type="gene ID" value="OSTLU_92808"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92808"/>
    <dbReference type="eggNOG" id="ENOG502QQ1X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_728427_0_0_1"/>
    <dbReference type="OMA" id="THGCESI"/>
    <dbReference type="OrthoDB" id="1934954at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102043">
        <property type="term" value="F:isopentenyl phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF1">
        <property type="entry name" value="ISOPENTENYL PHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/glutamate/uridylate kinase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="380" mass="39889" checksum="8867CE5505380FE6" modified="2007-05-15" version="1">MPSVAVVKFGGAVLTDKRQRGVVDARGLADCARVARLARDAGASLIIAHGAGSFGHGATRRTRATRRTRWTRRATDARGGDAVAAEAKACGCARGGDLRDAAFALGVDGTRAKVLELNRLVVDALRDAGVNARGMTPWREGWRTRGPGRPETSGRDEGRAVLDAVRDGVVPVIHGDVVEDVAQGTSVLSADTIVEMCAKWAMEEWPDECPRVVFCSDVFGVYDSPPTTRIINADVTDGDVPLRVNETETAVLLRDIIVDADADASDGTRVPWRCARASPLARLAEAADAAALDATFAIDDAIADVTGGVRAKLTTAIAIASYLPPGPPRVFLARPGAFAAEPSRVSDHALNAILAFDARGAPDDAALNNFIGTAIARRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYE7</accession>
    <name>A4RYE7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutamate-rich WD repeat-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_12589</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418159.1">
        <property type="nucleotide sequence ID" value="XM_001418122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYE7"/>
    <dbReference type="STRING" id="436017.A4RYE7"/>
    <dbReference type="GeneID" id="5002431"/>
    <dbReference type="Gramene" id="ABO96452">
        <property type="protein sequence ID" value="ABO96452"/>
        <property type="gene ID" value="OSTLU_12589"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12589"/>
    <dbReference type="eggNOG" id="KOG0302">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025272_2_1_1"/>
    <dbReference type="OMA" id="RHWKPNA"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900035">
        <property type="term" value="P:negative regulation of cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051972">
        <property type="entry name" value="Glutamate-rich_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903:SF1">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="9">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="242"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="286"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="334"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="441" mass="48605" checksum="AE92F62CE112CA96" modified="2007-05-15" version="1">MDADRGDGEAREARRKRPEVWRPGSAEDEDVELEYDESAYDALHAFSHEWPCLSLDVMRDDLGEGREVFPHEMTIVTGTQAMEATKNVLSVIRVSRIKKTRRDADADEDMEASDSDDDEDGGSDAPTLTVASVVHHGCVNRLRAMPQRPSTCASWSDSGHVMIWDLSAQLKKVMTSTNDSKGKIDPPSRVTPTQVFTGHKDEGYALDWSSVCEGRLASGDCAGAIHTWDMVQGKWDVGATPYTGHYSSVEDIQWSPTERDVFISCSADQTVCVWDTRQRAKPALRVKTHDSDVNVLSWNRLANSMVATGADDGSLRIWDLRNFNETNAQFVANFTFHRAAVTSVDWAPFDSAMLASSSADNTVCVWDLAVERDAEEEAAALAAKDNAAPPEDLPPQLMFVHQGLKDPKEIKWHRQIPGACVTTAADGFNIFKAYNVGPAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYF1</accession>
    <name>A4RYF1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_32006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418374.1">
        <property type="nucleotide sequence ID" value="XM_001418337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYF1"/>
    <dbReference type="STRING" id="436017.A4RYF1"/>
    <dbReference type="GeneID" id="5002434"/>
    <dbReference type="Gramene" id="ABO96667">
        <property type="protein sequence ID" value="ABO96667"/>
        <property type="gene ID" value="OSTLU_32006"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32006"/>
    <dbReference type="HOGENOM" id="CLU_845536_0_0_1"/>
    <dbReference type="OMA" id="CQAGKCS"/>
    <dbReference type="OrthoDB" id="527488at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN,N-TERMINAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967:SF2">
        <property type="entry name" value="SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672979" description="Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein" evidence="2">
        <location>
            <begin position="33"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="3">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="3">
        <location>
            <begin position="216"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="366" mass="37014" checksum="FEA70D266936C13D" modified="2007-05-15" version="1">MPAGRIRRRAARALSIACALALGRDGVTRAEAQASDGNCVAAEQTAIFVAFSENAPDAVFRSDDGCLAGGGRGVGCCPGSVCKACEGDSTSRFYSCKCEPCAAGTVQPLAAQKTCVSCPAGWFNSRTGQATCEPCPVGTFSTKVGNTVGCTACGAGTSGKSTLEDYYEKTTRSWRAPATGDGSTFDSTLAATSCTDCPAGTSGGGAGDACTPCAPGYYSAARAETCTPCPVGTYSVLSGGASIDSCIPCAAGESNNAIGSTECWQVCPIALLSCAADAVRARGAYDALELARARPRISYTDDGIDDYRARLCKTGCETFATDHWCASFGLPNVNDCDQYAPPPPPPAPPGDVADPNATAANASAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYW3</accession>
    <name>A4RYW3_OSTLU</name>
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        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_5960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="5002386"/>
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        <property type="protein sequence ID" value="ABO96757"/>
        <property type="gene ID" value="OSTLU_5960"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5960"/>
    <dbReference type="eggNOG" id="KOG0724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1014071_0_0_1"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="protein REVEILLE 6 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Myb_dom"/>
    </dbReference>
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        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="24"/>
            <end position="74"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="275" mass="29506" checksum="BD5C301D3E1BAA87" modified="2007-05-15" version="1" fragment="single">TTTTTTTTTTTTEGAPVKVRKPYTITKKREKWSDEEHALFVESLKKYGRAWRKIEEHIGTKTAVQIRSHAQKFFSKLQKEQAARGSASGSDAPAGSQGDSSKRRGARGSTSGSKKSRRSVSPDLNLKIPPARPKKKPDHPYPKKATSQQPSGGSGEGKSTGTAQNMMGSATQAEHIANASSSAAVAAVLSVASDKMQTSLQHDLRAGYFGVPPGAGMFAQPGLFPVQHMMNPYVGMSNPAAGAQNPPQMSNPQQFINYINFLTNMWRQNANAMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ33</accession>
    <name>A4RZ33_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418261.1">
        <property type="nucleotide sequence ID" value="XM_001418224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ33"/>
    <dbReference type="STRING" id="436017.A4RZ33"/>
    <dbReference type="GeneID" id="5002279"/>
    <dbReference type="Gramene" id="ABO96554">
        <property type="protein sequence ID" value="ABO96554"/>
        <property type="gene ID" value="OSTLU_32238"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32238"/>
    <dbReference type="eggNOG" id="ENOG502S7NK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062342_0_0_1"/>
    <dbReference type="OMA" id="RLFNDQY"/>
    <dbReference type="OrthoDB" id="565629at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF46">
        <property type="entry name" value="PHYTANOYL-COA HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="30413" checksum="C359CA0495FE516A" modified="2007-05-15" version="1">MVTDEVLRELCERFKTNGYVVVEDYLDDYVVRACLNEFETVLRARVGNEGDEDARFGRLEALGCVAQVNAPREADAYDANVNHRARGRSSVCDAIVSETLTRKGAIGSIAIALLGHDDTRLFNDQYVAKPPARADSALRASCFEWHRDSQWCDDGEDGSNVPYLSCWVALDDVSEENGTLRMLPYPPAASEATHRERASAYPPMSDLPSPMSGDACEDCGRLLTIRAGSVVFFSDVVFHCSGPNLSESIRRAWMPQFSAGPIVRADGSPVSLVARIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ52</accession>
    <name>A4RZ52_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418515.1">
        <property type="nucleotide sequence ID" value="XM_001418478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ52"/>
    <dbReference type="GeneID" id="5002479"/>
    <dbReference type="Gramene" id="ABO96808">
        <property type="protein sequence ID" value="ABO96808"/>
        <property type="gene ID" value="OSTLU_92920"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92920"/>
    <dbReference type="eggNOG" id="ENOG502SD22">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_537929_0_0_1"/>
    <dbReference type="OMA" id="VRRPYCH"/>
    <dbReference type="OrthoDB" id="497336at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="154"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="507" mass="56366" checksum="8B5F9F6BC3CD5840" modified="2007-05-15" version="1">MTDDATRSTDEQAIERGIRAQDARRARFGRPSSTARATTESDAEASVDVDAVNGVSQRRLGELRNRAVEAMRFAPSWLKQIQMPPGTSPGSVIPVVGSFEELYRIAQIACLNGQPLEEIEEFFRGKEDVRVLELSSCEQRAIVTTDHRNRTHTVSLRGTKNIKNVAQNLRLGTAPTGRAEDVPVPMHRGYRNIAQRCLEAIEPLLLDGYELQLTGHSLGGAAAVALALLLHQKKKTKIRRVVTFGSPKLGPKETAQAIEEIDILRVVQKDDIIPLLPMSRPLVRRPYCHVGEGLVLDNDRPGVFADLPREWGAAGILWRQRVSIESVMNTTTMSTMEASQVTRQVSNVAKGVAKGLSKPITAAKRARTSFLAAFSMPTNEIELEAEVKDLIAATESKESFLSIQEEFDASSASPGVFEDQNETATQRIGPTIFERLWALRQYSPEERVERLDSHRMYRYVAIIRDTIENQPTRVPLADIYEPSTSPKKSRETPIPQLSKAILSIRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZB6</accession>
    <name>A4RZB6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_87610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418303.1">
        <property type="nucleotide sequence ID" value="XM_001418266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZB6"/>
    <dbReference type="GeneID" id="5002183"/>
    <dbReference type="Gramene" id="ABO96596">
        <property type="protein sequence ID" value="ABO96596"/>
        <property type="gene ID" value="OSTLU_87610"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87610"/>
    <dbReference type="eggNOG" id="KOG4750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_7_1_1"/>
    <dbReference type="OMA" id="NHGCSLD"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04647">
        <property type="entry name" value="LbH_MAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF23">
        <property type="entry name" value="ACETYLTRANSFERASE C18B11.09C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="25305" checksum="BBC8E3A28F1F50EC" modified="2007-05-15" version="1">MFAARAAAPRAPRATHASRASFARASLEKTPDFTAQKRKRVSFMPRLLDNNRAKHLTSDIQTWQRNVQRDISAVETVRFGDDCFVGEGTEIFAEPGRDVALGDGARVAARCFIHGPCAIGARASLNANAHIEGGAVGVTIGDDTRIGPRFSAFAFNHVFDDPETNIREQGVTSQGITIGKDVWIGASVCVTDGVHIGDHSVVGMGSVVTRDVEPYAVVAGNPARVIRYRKRPPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZF0</accession>
    <name>A4RZF0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vesicle-fusing ATPase</fullName>
            <ecNumber evidence="4">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_41487</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="4"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418564.1">
        <property type="nucleotide sequence ID" value="XM_001418527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZF0"/>
    <dbReference type="STRING" id="436017.A4RZF0"/>
    <dbReference type="GeneID" id="5002454"/>
    <dbReference type="Gramene" id="ABO96857">
        <property type="protein sequence ID" value="ABO96857"/>
        <property type="gene ID" value="OSTLU_41487"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41487"/>
    <dbReference type="eggNOG" id="KOG0741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008037_2_1_1"/>
    <dbReference type="OMA" id="DGMHALN"/>
    <dbReference type="OrthoDB" id="9982946at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000154">
        <property type="entry name" value="Vesicle-fusing ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000166">
        <property type="entry name" value="vesicle-fusing ATPase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000127">
        <property type="entry name" value="Vesicular-fusion protein SEC18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="45"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="328"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="550" mass="58373" checksum="67D09FE0F8D7B45D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZN2</accession>
    <name>A4RZN2_OSTLU</name>
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        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
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    <gene>
        <name evidence="7" type="ORF">OSTLU_32448</name>
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    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABO96892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418562.1"/>
    </dbReference>
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    <dbReference type="Gramene" id="ABO96892">
        <property type="protein sequence ID" value="ABO96892"/>
        <property type="gene ID" value="OSTLU_32448"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32448"/>
    <dbReference type="eggNOG" id="ENOG502SE2I">
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    </dbReference>
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    <dbReference type="OrthoDB" id="498888at2759"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
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        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46408">
        <property type="entry name" value="BASIC LEUCINE ZIPPER 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46408:SF10">
        <property type="entry name" value="BASIC LEUCINE ZIPPER 63"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
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        <location>
            <begin position="270"/>
            <end position="333"/>
        </location>
    </feature>
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            <end position="47"/>
        </location>
    </feature>
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            <end position="217"/>
        </location>
    </feature>
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            <end position="291"/>
        </location>
    </feature>
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        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
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            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
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            <end position="197"/>
        </location>
    </feature>
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            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
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            <end position="247"/>
        </location>
    </feature>
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        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="42573" checksum="55600AF02E19132A" modified="2007-05-15" version="1">MDRVPSADDLMATFLWNAQRASAGTPSNGTSGAAAHGARGVNRTPSQHEMESYYNAMMASAAHGAHAGFGAYGALDGSIAHARDAAGGAGSAPGSREGTPGIPRVASIDVLRKMIMSGGLGGGGGPGGASPGSATPTTAAAFSAFASGANLDALGAAVAMEQSKADDEGKKTTTTRSGAKRSGRKPAAKAPAAKKAKAPPAKKAAAATTTRGGKAAKDAVASPAKAAAKAPAAKAPAAKAKAVAAKSEPLSSDLDHDSDGDSRDGDGNGDMRRRRRMLSNRESARRSRRRKIEHVATLEGQIAQLTAELTAALQHTQGVEQRYQALVRENHTIRAEKDRLLQLLREAGPPGGGVTTPKTGSAMERKSSLQRISSNGDIKGELGKGSPTIGLGTGFVPFRSLQSYENLLLLQQKSEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZR7</accession>
    <name>A4RZR7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SS18 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_32480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418617.1">
        <property type="nucleotide sequence ID" value="XM_001418580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZR7"/>
    <dbReference type="STRING" id="436017.A4RZR7"/>
    <dbReference type="GeneID" id="5003047"/>
    <dbReference type="Gramene" id="ABO96910">
        <property type="protein sequence ID" value="ABO96910"/>
        <property type="gene ID" value="OSTLU_32480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32480"/>
    <dbReference type="eggNOG" id="KOG3227">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2594133_0_0_1"/>
    <dbReference type="OMA" id="AECVQHQ"/>
    <dbReference type="OrthoDB" id="10265171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007726">
        <property type="entry name" value="SS18_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23107:SF0">
        <property type="entry name" value="IP09280P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23107">
        <property type="entry name" value="SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05030">
        <property type="entry name" value="SSXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SS18 N-terminal" evidence="8">
        <location>
            <begin position="22"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="80" mass="8580" checksum="0EAF70C73CAACFAA" modified="2007-05-15" version="1">MSGEQAGPSFVTPGDAAAPSVVTTELIQKYLDENQQLILAILENQNVGKLAECAKYQTKLQENLMYLAAIADAKPAEPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S045</accession>
    <name>A4S045_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418909.1">
        <property type="nucleotide sequence ID" value="XM_001418872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S045"/>
    <dbReference type="GeneID" id="5002996"/>
    <dbReference type="Gramene" id="ABO97202">
        <property type="protein sequence ID" value="ABO97202"/>
        <property type="gene ID" value="OSTLU_32612"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32612"/>
    <dbReference type="HOGENOM" id="CLU_1498720_0_0_1"/>
    <dbReference type="OrthoDB" id="10480343at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="180" mass="19678" checksum="7E340255DD837EF8" modified="2007-05-15" version="1">MDFLYASAEVHTLPPRKRLACVLRDVAHSPTDLGSKKARLAGEAYVRTALRDPRLLGKALEIVSEERYDVDGGSSDRENGGASASTKSKKGPRNMSSSSLNTATATTEKKKKKLSTKRDRSTTQALKSDEDDDDDSNAEPKELTDEQMAMKLHLEMNASPRMSRGSSRSTQMLTGRALFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S083</accession>
    <name>A4S083_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418930.1">
        <property type="nucleotide sequence ID" value="XM_001418893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S083"/>
    <dbReference type="STRING" id="436017.A4S083"/>
    <dbReference type="GeneID" id="5002684"/>
    <dbReference type="Gramene" id="ABO97223">
        <property type="protein sequence ID" value="ABO97223"/>
        <property type="gene ID" value="OSTLU_16147"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16147"/>
    <dbReference type="HOGENOM" id="CLU_1017039_0_0_1"/>
    <dbReference type="OrthoDB" id="10440400at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="274" mass="29352" checksum="E433A506E954B1F3" modified="2007-05-15" version="1">MEQALCAAPSARGITVADLEVVRECAGSPGPLKRFVPETSSPSDIMMNTPPHLRGGEMTSGSKRSIEDSPSYTLSPQSALKPPSFGDGQLGSSYGDGRDKSVSPRSASSPPVAVYSYATSAGSARGGNGAFAGRPPRGDRATFKPGSLPHPRSGTSFGNRADAKQAQPAIKFTGAAFRSARDEYLDRVFGFLFKEVGDGEWMAIKSKTGVSGRCRKPVTMPETYLEFFDSHRDKFEINAERTKVRLRNQRTRSDSGDSDDTNVESLSDSLKATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S164</accession>
    <name>A4S164_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_42472</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. TRA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419308.1">
        <property type="nucleotide sequence ID" value="XM_001419271.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S164"/>
    <dbReference type="GeneID" id="5003433"/>
    <dbReference type="Gramene" id="ABO97601">
        <property type="protein sequence ID" value="ABO97601"/>
        <property type="gene ID" value="OSTLU_42472"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42472"/>
    <dbReference type="eggNOG" id="KOG0889">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000129_1_0_1"/>
    <dbReference type="OMA" id="CLDLYGQ"/>
    <dbReference type="OrthoDB" id="5570127at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05163">
        <property type="entry name" value="PIKK_TRRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046807">
        <property type="entry name" value="Tra1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046805">
        <property type="entry name" value="Tra1_ring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF1">
        <property type="entry name" value="TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20175">
        <property type="entry name" value="Tra1_central"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20206">
        <property type="entry name" value="Tra1_ring"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAT" evidence="4">
        <location>
            <begin position="2654"/>
            <end position="3196"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="3">
        <location>
            <begin position="3427"/>
            <end position="3754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1979"/>
            <end position="2066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3205"/>
            <end position="3233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2010"/>
            <end position="2019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="3216"/>
            <end position="3225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="3790" mass="425369" checksum="B459B2D0A8326C20" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S178</accession>
    <name>A4S178_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S29, component of cytosolic 80S ribosome and 40S small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS29</name>
        <name evidence="6" type="ORF">OSTLU_42310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419101.1">
        <property type="nucleotide sequence ID" value="XM_001419064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S178"/>
    <dbReference type="STRING" id="436017.A4S178"/>
    <dbReference type="GeneID" id="5003408"/>
    <dbReference type="Gramene" id="ABO97394">
        <property type="protein sequence ID" value="ABO97394"/>
        <property type="gene ID" value="OSTLU_42310"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42310"/>
    <dbReference type="eggNOG" id="KOG3506">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177289_1_1_1"/>
    <dbReference type="OMA" id="NDVWNSH"/>
    <dbReference type="OrthoDB" id="521448at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="56" mass="6648" checksum="BEE8B28D11FD5F83" modified="2007-05-15" version="1">MGHNDIWASHPANYGKGSRRCRVCENQWAIIRKYDLNICRQCFREYAKDIGFVKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1I4</accession>
    <name>A4S1I4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419153.1">
        <property type="nucleotide sequence ID" value="XM_001419116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1I4"/>
    <dbReference type="GeneID" id="5003478"/>
    <dbReference type="Gramene" id="ABO97446">
        <property type="protein sequence ID" value="ABO97446"/>
        <property type="gene ID" value="OSTLU_16484"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16484"/>
    <dbReference type="HOGENOM" id="CLU_1257910_0_0_1"/>
    <dbReference type="OMA" id="VWPLCFA"/>
    <dbReference type="OrthoDB" id="497970at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="220" mass="23560" checksum="0061637E3C66FCC0" modified="2007-05-15" version="1">MATRRARATTRQPRAKDAAADAADARRGKGAASTREPRRAELRAEKAARWPMCMAIAIEKTTVVRGVVVACAAVALAVALTLMDWSDDGAGAFLRKIRWALNPLSVFVACELNVLITAFVVLFPVTYAQAAIDEREGVEESDTLRLLKLPAIVAEFAVGSKVAIARLGDVIVRDFSLFMVVYLSFAGYWLALDGDPIDSGVGASSVHEMEGGVSVHSLVQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-10-05" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1K1</accession>
    <name>ARGJ_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arginine biosynthesis bifunctional protein ArgJ, chloroplastic</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">Glutamate N-acetyltransferase</fullName>
                <shortName evidence="1">GAT</shortName>
                <ecNumber evidence="1">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">Ornithine acetyltransferase</fullName>
                <shortName evidence="1">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="1">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="1">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">N-acetylglutamate synthase</fullName>
                <shortName evidence="1">AGS</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="1">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="1">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name type="ORF">OSTLU_33128</name>
    </gene>
    <organism>
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">This protein may be expected to contain an N-terminal transit peptide but none has been predicted.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="1"/>
    <dbReference type="EC" id="2.3.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419163.1">
        <property type="nucleotide sequence ID" value="XM_001419126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1K1"/>
    <dbReference type="SMR" id="A4S1K1"/>
    <dbReference type="STRING" id="436017.A4S1K1"/>
    <dbReference type="MEROPS" id="T05.002"/>
    <dbReference type="EnsemblPlants" id="ABO97456">
        <property type="protein sequence ID" value="ABO97456"/>
        <property type="gene ID" value="OSTLU_33128"/>
    </dbReference>
    <dbReference type="GeneID" id="5003448"/>
    <dbReference type="Gramene" id="ABO97456">
        <property type="protein sequence ID" value="ABO97456"/>
        <property type="gene ID" value="OSTLU_33128"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33128"/>
    <dbReference type="eggNOG" id="KOG2786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027172_1_1_1"/>
    <dbReference type="OMA" id="WGRIVMA"/>
    <dbReference type="OrthoDB" id="2017946at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00111"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006592">
        <property type="term" value="P:ornithine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.340:FF:000001">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.70.12:FF:000001">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2330.10">
        <property type="entry name" value="arginine biosynthesis bifunctional protein suprefamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="entry name" value="ArgJ beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.70.12">
        <property type="entry name" value="L-amino peptidase D-ALA esterase/amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003802">
        <property type="entry name" value="PRK05388.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100:SF0">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="DmpA/ArgJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0055">Arginine biosynthesis</keyword>
    <keyword id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword id="KW-0150">Chloroplast</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0934">Plastid</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000397982" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="1">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000397983" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="1">
        <location>
            <begin position="239"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="1">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="1">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="1">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03124"/>
        </source>
    </evidence>
    <sequence length="461" mass="47495" checksum="8D45526E26E951CB" modified="2007-05-15" version="1" precursor="true">MTSRGRARASDRRARGAVVASGKIDFTDAGCFELPYAPVAEALLPEGPWKVVEGGVCAAKGFKVAGYKAGLRAKGTRADCALIVADEDATCAGIFTTNIMCAAPVTYCKKQLAGKPTARALLINAAQANAATGDQGAADAQATAEELSKSLGVAEEDILLMSTGVIGKRIKLDKLMPAIPILSANVESSTAAANAAATAICTTDLVRKTVAIEVQIGGKTVCMGGMAKGSGMIHPNMATMLGVVTCDADVTPEVWRNITSRAGAASFNQISVDGDTSTNDSLVCFASGKAGNAKITSVDSAEGKLLEQALTAVCRGLAKAIAWDGEGATCLIECNVSGAADDEDARVIARSVVCSSLAKAAIFGHDPNWGRLACAAGYAAPVKNRFDQNDLKLSLGPHQLMDKGQPLDFDAVAASRYLKEVTGVHGTCVVDISVGNGSGRGQAWGCDLSYDYVKINAEYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1L8</accession>
    <name>A4S1L8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419387.1">
        <property type="nucleotide sequence ID" value="XM_001419350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1L8"/>
    <dbReference type="GeneID" id="5003225"/>
    <dbReference type="Gramene" id="ABO97680">
        <property type="protein sequence ID" value="ABO97680"/>
        <property type="gene ID" value="OSTLU_33144"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33144"/>
    <dbReference type="eggNOG" id="ENOG502T1VG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2065427_0_0_1"/>
    <dbReference type="OrthoDB" id="498789at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="119" mass="13184" checksum="3C4AEF0B557450B0" modified="2007-05-15" version="1">MAPHDTEAQITTPKEPLPPPPTSAAMTLEQYRAYVASQSHTKGTVHATPPEEKAEQEDKKKHGWWPCQSYKCAGKQLNPKAVEKCEACGALRRLDSGGQAFTASTSAAQHRWNTEVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1N8</accession>
    <name>A4S1N8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribulokinase/uridine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_88056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419398.1">
        <property type="nucleotide sequence ID" value="XM_001419361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1N8"/>
    <dbReference type="STRING" id="436017.A4S1N8"/>
    <dbReference type="GeneID" id="5003181"/>
    <dbReference type="Gramene" id="ABO97691">
        <property type="protein sequence ID" value="ABO97691"/>
        <property type="gene ID" value="OSTLU_88056"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88056"/>
    <dbReference type="eggNOG" id="KOG2702">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067202_0_1_1"/>
    <dbReference type="OMA" id="EVWFVEV"/>
    <dbReference type="OrthoDB" id="6362633at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="2">
        <location>
            <begin position="62"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="261" mass="29232" checksum="CCD91215B89A9FBD" modified="2007-05-15" version="1">MSTARVDVRATTSRRSSCPPRARRPSLRARATQSDGFNAVVQERVDALIRARDDAPATQRFVAIAGPPGGGKSTFAEAVRVGYNERRNGEDACVVVPMDGFHWSLAELAAGRAGDADEARRRRGAPWTFDAISFVECVKILRSRGYGEIPTFDHATHDPVEGGCRVERRHETVLIEGNYVLLPERPWRDLVDENVFDETWFVDTDVEEAMRRIIQRHVAVGRSEEEARMRAESNDALNARLVVQQCRTLADVLIPCVSFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1W1</accession>
    <name>A4S1W1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_33240</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419435.1">
        <property type="nucleotide sequence ID" value="XM_001419398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1W1"/>
    <dbReference type="STRING" id="436017.A4S1W1"/>
    <dbReference type="GeneID" id="5003133"/>
    <dbReference type="Gramene" id="ABO97728">
        <property type="protein sequence ID" value="ABO97728"/>
        <property type="gene ID" value="OSTLU_33240"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33240"/>
    <dbReference type="eggNOG" id="KOG2782">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038422_3_0_1"/>
    <dbReference type="OMA" id="EEKHWRL"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00006">
        <property type="entry name" value="16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265:SF0">
        <property type="entry name" value="12S RRNA N4-METHYLCYTIDINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="S-ADENOSYL-METHYLTRANSFERASE MRAW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="314" mass="35191" checksum="BE4BAF14AA546AB2" modified="2007-05-15" version="1">MDEVLEAFRDVRARTHVDGTLGAGGHARAMIEAHEEMEHFVGFDVDASAHALARPRLERARAATRGDEATTTLRLSLVEANFRRMREALRALDVDGVDSVVLDLGVSSMHLDRAERGFSFMNDGPLDMRMGESATTTAEEIVNAWPEEEIGRILREYGEEKHWRLLARRICERRAEKEIRTTRELVDAIGNVPGKWGSIHPATRTFQGIRIAVNDELGAVEDVIPAAIEALRPGGRLAIISFHSLEDSIVKRRFRHFAGRAEPPSEEVNRYMPQPEAPPKIVKLITRKPKVPTSAEIDVNVRSRSAKLRVCEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S210</accession>
    <name>A4S210_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419244.1">
        <property type="nucleotide sequence ID" value="XM_001419207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S210"/>
    <dbReference type="STRING" id="436017.A4S210"/>
    <dbReference type="GeneID" id="5003102"/>
    <dbReference type="Gramene" id="ABO97537">
        <property type="protein sequence ID" value="ABO97537"/>
        <property type="gene ID" value="OSTLU_24984"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24984"/>
    <dbReference type="eggNOG" id="ENOG502S92I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_779252_0_0_1"/>
    <dbReference type="OMA" id="NWMASTT"/>
    <dbReference type="OrthoDB" id="425248at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="44361" checksum="6425D93A9BD6B417" modified="2007-05-15" version="1">MATTTTTTTTTTRIDRVAASSSRAASRRRSSTSTPKSATARSRTTVRRATTSDDDVADDASTSERARVERWRARARTMRAKILKGYLARLGARSDDCLEKDELVDRLAETWMTKCENFAITVPLRQLGNIGGNPRSGYALVTLDVGGDIGLCDFVIDTGATTALITPKALDMLDKDQVKEGAAVRGLTGTGETLRQKVSISEVRLGSKEFVLDAVVTDLTAVGLPATIGGLLGLDWLGNFEVEFDFEQSVITFWPPGSVKNGAVAVEDLVRVRLNQHPVGLKTVRCSLNGAELDAIVDMGSFFSVVNWMASTTAGIGPDSDKVKRGGLQVTGVDGKSMAMAMAPYDLRVLGDGEEDLTSTYQGMCCIGDLPAFAALGASVSPFMALGLDVIGRGRMVFNAKDNAMYLSKGDVTYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S286</accession>
    <name>A4S286_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_33363</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419489.1">
        <property type="nucleotide sequence ID" value="XM_001419452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S286"/>
    <dbReference type="STRING" id="436017.A4S286"/>
    <dbReference type="GeneID" id="5003912"/>
    <dbReference type="Gramene" id="ABO97782">
        <property type="protein sequence ID" value="ABO97782"/>
        <property type="gene ID" value="OSTLU_33363"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33363"/>
    <dbReference type="eggNOG" id="KOG2857">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117355_0_0_1"/>
    <dbReference type="OMA" id="DKASYRC"/>
    <dbReference type="OrthoDB" id="18412at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070761">
        <property type="term" value="C:pre-snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23024">
        <property type="entry name" value="zf-HIT_ZNHIT2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF11">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="140" mass="15632" checksum="B59B479D0B47D48E" modified="2007-05-15" version="1">MPSAAPCVACAAETSSYKCPTCRSPYCSVACYKSHRETTCEPVRASTAPAVAERANETREQPSRAFEEDSEDELGTRARREDLQRVADDASVREKLRSERLREIIRAIDAAKDGEKALAKAREDPEFRAFTEDALSLFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S297</accession>
    <name>A4S297_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419711.1">
        <property type="nucleotide sequence ID" value="XM_001419674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S297"/>
    <dbReference type="GeneID" id="5003583"/>
    <dbReference type="Gramene" id="ABO98004">
        <property type="protein sequence ID" value="ABO98004"/>
        <property type="gene ID" value="OSTLU_93214"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93214"/>
    <dbReference type="eggNOG" id="ENOG502SDF8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1443623_0_0_1"/>
    <dbReference type="OMA" id="WYVLVPG"/>
    <dbReference type="OrthoDB" id="43106at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="197" mass="21160" checksum="8A6E39C7F6210EB0" modified="2007-05-15" version="1">MRAVTATTTAVLHAARAPCRAPCRASSPPPRASTSRRAFEADVADAAPRAISAVDPIAAAYVPTPIDPALLRDELVVLGAIGAMTAYWWLVLVPSARVRLAKNKKSGELRAYLDDLARSDGKGLEKWFYAQWLTKIDPETRYLLRDDAPAAARRVETLEDVARAARRAPKFWSGDNPVLVGTALTIGLAALFSGVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2J0</accession>
    <name>A4S2J0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_33470</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="4"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419759.1">
        <property type="nucleotide sequence ID" value="XM_001419722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2J0"/>
    <dbReference type="STRING" id="436017.A4S2J0"/>
    <dbReference type="GeneID" id="5003596"/>
    <dbReference type="Gramene" id="ABO98052">
        <property type="protein sequence ID" value="ABO98052"/>
        <property type="gene ID" value="OSTLU_33470"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33470"/>
    <dbReference type="eggNOG" id="KOG2784">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025086_2_2_1"/>
    <dbReference type="OMA" id="QIEGWVM"/>
    <dbReference type="OrthoDB" id="238316at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000178">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040724">
        <property type="entry name" value="PheRS_DBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040725">
        <property type="entry name" value="PheRS_DBD3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003210">
        <property type="entry name" value="PRK04172.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF40">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18552">
        <property type="entry name" value="PheRS_DBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18553">
        <property type="entry name" value="PheRS_DBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="229"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="494" mass="55437" checksum="D71004DE1F4FB482" modified="2007-05-15" version="1">MSDADAIERDVLAAIARDGIADTASASARHGVDHQAVVGVVKRLTAANMVVARAIERSRTTLTAEGERCVDEGSPEARAFACVPEEGIELDAFRTRAGPGAADVGFKQAMQRNWLAMVKGATPRVERRVETIEDDVREALRALRGGETVDAKTLETLTKKRKLAKEERWKEYELTKGAEFALERKVLPADLTKEMMNEGSWRGQAFKAYNLVPGAGAQPASGHVHPLLKVRQAFREIFFSLGFSEMPTNNFVESGFWNFDTLIQPQQHPARDAHDTFFMKTPATMNFAPEDYVERVRKMHETGGNGSIGHQYAWKRAEADKNILRTHTTAVSARMLYDIAQTGFKPARMFSIDRVFRNEAVDRTHLAEFHQVEGVICDKDLTLGDLIGVLYQFFERLGMTQLRFKPAFNPYTEPSMEIFAFHPMLDKWVEVGNSGMFRPEMLEPMGLPEDVNVIAWGLSLERPTMIMYGIDNIRDLFGSKMQITSVKNNPICTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2J2</accession>
    <name>A4S2J2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_16752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419760.1">
        <property type="nucleotide sequence ID" value="XM_001419723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2J2"/>
    <dbReference type="STRING" id="436017.A4S2J2"/>
    <dbReference type="GeneID" id="5003597"/>
    <dbReference type="Gramene" id="ABO98053">
        <property type="protein sequence ID" value="ABO98053"/>
        <property type="gene ID" value="OSTLU_16752"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16752"/>
    <dbReference type="eggNOG" id="KOG3062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1135961_0_0_1"/>
    <dbReference type="OMA" id="YERISFD"/>
    <dbReference type="OrthoDB" id="8983at13792"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052648">
        <property type="entry name" value="Ser-tRNA(Sec)_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20873">
        <property type="entry name" value="L-SERYL-TRNA(SEC) KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20873:SF0">
        <property type="entry name" value="L-SERYL-TRNA(SEC) KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="215"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="26730" checksum="FCE4D90D5B32E076" modified="2007-05-15" version="1" fragment="single">MATASDAASRPRAARAPREDASKTLVLVLCGLPGVGKTTLARALARRARESGHDAHHARYDARELRAMTREDGTTAFEPARWRAARAEAAADVDAATRRGNAREDGVKTVVIVDDNMYYRGMRWEVFRAAREARASCACAHVTAPTKEARRRNRNREGAEAVPEEVFERMTRAFEAPAVTTPGDGATFPAFVVDATEETDVDAAWSRALEFWGPAPDVPASEAERELEREAARAETAKSALHALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2K4</accession>
    <name>A4S2K4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419546.1">
        <property type="nucleotide sequence ID" value="XM_001419509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2K4"/>
    <dbReference type="GeneID" id="5003664"/>
    <dbReference type="Gramene" id="ABO97839">
        <property type="protein sequence ID" value="ABO97839"/>
        <property type="gene ID" value="OSTLU_93237"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93237"/>
    <dbReference type="eggNOG" id="ENOG502SZXB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1398450_0_0_1"/>
    <dbReference type="OrthoDB" id="498754at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="195" mass="21752" checksum="841CDA74B3B77820" modified="2007-05-15" version="1">MRRCARRALERATRAATATTRRGRASSSGDAPSKATKATTTTRDDGGTENPLRGVMFPWERAVLHSERWAGELKPWQKAYWAAFALGCAFVVGARAKRYHDDQESEEARRRTMEANKRALRGALEGRSFIGASGEDEEDEDEDPFDGMSPEEIEALVKREAGPSGDVYDGMTPEEINEHEEKFRGKGNLTWKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2L0</accession>
    <name>A4S2L0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419548.1">
        <property type="nucleotide sequence ID" value="XM_001419511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2L0"/>
    <dbReference type="GeneID" id="5003604"/>
    <dbReference type="Gramene" id="ABO97841">
        <property type="protein sequence ID" value="ABO97841"/>
        <property type="gene ID" value="OSTLU_93240"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93240"/>
    <dbReference type="eggNOG" id="ENOG502RZJ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_732350_0_0_1"/>
    <dbReference type="OMA" id="KWIGPPR"/>
    <dbReference type="OrthoDB" id="496551at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="101"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="378" mass="43122" checksum="59905F0102AD7AFB" modified="2007-05-15" version="1">MRDVAEADDAPPRPWRPDDDGAGGDDARADVDDPDEWLRGQLAGMPIEKDYPELVDAAVRCMGEWKKRMPKSVWLRVTKSGRLAKELNESAPVLAKTMEYVRDIDVRTPSERVVVVDLCSGFGYLAMFLSEILPKEKVAEIVLVDKMWSMMNRTPKPHHISWSHIYGEGDWKYDWPIELSTRKVDLKDYAQVNQMSVHLFSRWNGPFIVLGIHLCGTLSIKAVEMFNKNSNVKHLILKPCCLPDWSWTYRAESGYFPPVGAHKHLIPTKAVCSKGKWKKNKWIGPPRSHLKIKFESWNDHLCRSINDEDGNISTSLQEIQVQASHFQNLFIFGDRQRIRKCHVREATGVEFPTPSGVDAKRWSPTGTGYGTHTRTLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2L1</accession>
    <name>A4S2L1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_35145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419771.1">
        <property type="nucleotide sequence ID" value="XM_001419734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2L1"/>
    <dbReference type="STRING" id="436017.A4S2L1"/>
    <dbReference type="GeneID" id="5003605"/>
    <dbReference type="Gramene" id="ABO98064">
        <property type="protein sequence ID" value="ABO98064"/>
        <property type="gene ID" value="OSTLU_35145"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35145"/>
    <dbReference type="eggNOG" id="KOG3367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073615_0_0_1"/>
    <dbReference type="OMA" id="CATCASY"/>
    <dbReference type="OrthoDB" id="9449045at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006178">
        <property type="term" value="P:guanine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009845">
        <property type="term" value="P:seed germination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050408">
        <property type="entry name" value="HGPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340:SF1">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="171" mass="18974" checksum="1B86B465333C2805" modified="2007-05-15" version="1">MNEFSVFVPVTTGAMMFASDLLRQTYVTQRTLRAELDRPYDRPVIACATCASYGDGTVSGEAKTAHAPSEATVRGKRCVIIEDIIDTGKTVVALAKELYARGAEEVAVIALMDKQARRDEACAKWMREKDMKIAAAFMCPDEFVVGYGLDYRGKYRELPFVGILKPEIFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2P7</accession>
    <name>A4S2P7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_25047</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419786.1">
        <property type="nucleotide sequence ID" value="XM_001419749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2P7"/>
    <dbReference type="STRING" id="436017.A4S2P7"/>
    <dbReference type="GeneID" id="5003776"/>
    <dbReference type="Gramene" id="ABO98079">
        <property type="protein sequence ID" value="ABO98079"/>
        <property type="gene ID" value="OSTLU_25047"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25047"/>
    <dbReference type="eggNOG" id="KOG1290">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_81_13_1"/>
    <dbReference type="OMA" id="NHKGPNG"/>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000339">
        <property type="entry name" value="Serine/threonine-protein kinase SRPK-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="55"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO98079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="412" mass="46648" checksum="F43696B6CF566BB7" modified="2007-05-15" version="1">MTRSSSDTSSSDARDVDDVDSRSASSSDEDEGTDGYKRGGYHPVSIGERYNDDRYVVVKKLGWGHFSTCWLVEDARARGASGEDGAVKTLRALKIQKSSGSYTEAARDEIEILKQVKEGDTGDGDEATNVVCLYDSFTHEGPNGTHVCMVFDVLGDNLLTLIKRYEYLGVPLLGVKALTRAMLKGLRYLHGKKNIIHTDLKPENVLLTFKLPEKKRRRKKRGKSSKKKATEDEAKPTIESQIEALDNLDAKICDLGNACWVDRQFTQDIQTRQYRSPEVILGAKYDTSADIWSLACIVFELATGDVLFDPRSGKDYDRDEDHLALMMELIGRMPKHLALSGKYSKEFFNRNGELRHIRSLKFWPCERVLMEKYNMSETDSKELSDFLSPMLDFNPSKRASAEQMLEHPWLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2V9</accession>
    <name>A4S2V9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS7</name>
        <name evidence="5" type="ORF">OSTLU_33586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419814.1">
        <property type="nucleotide sequence ID" value="XM_001419777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2V9"/>
    <dbReference type="STRING" id="436017.A4S2V9"/>
    <dbReference type="GeneID" id="5003765"/>
    <dbReference type="Gramene" id="ABO98107">
        <property type="protein sequence ID" value="ABO98107"/>
        <property type="gene ID" value="OSTLU_33586"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33586"/>
    <dbReference type="eggNOG" id="KOG3320">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088621_2_0_1"/>
    <dbReference type="OMA" id="AAYHKVQ"/>
    <dbReference type="OrthoDB" id="1724687at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047861">
        <property type="entry name" value="Ribosomal_eS7_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00948">
        <property type="entry name" value="RIBOSOMAL_S7E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18755" checksum="A39CD00283BA6922" modified="2007-05-15" version="1">MAMIELEASNAELKADLKDLYINSAAEVEVAGGRTAIVIHVPYRALKSYHKIQQRLVRELEKKFSGKDVVIVANRRIMPVPSNNMARSRPRSRTLTAVHAALLEDLVYPTEIVGKRQRYRLDGSRLLKVYLDPKDRSTTEYKLDTFAGVYKKLTGKECSFQFPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3H7</accession>
    <name>A4S3H7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nitrate reductase [NADH]</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_37938</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nitrate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420098.1">
        <property type="nucleotide sequence ID" value="XM_001420061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3H7"/>
    <dbReference type="STRING" id="436017.A4S3H7"/>
    <dbReference type="GeneID" id="5004252"/>
    <dbReference type="Gramene" id="ABO98391">
        <property type="protein sequence ID" value="ABO98391"/>
        <property type="gene ID" value="OSTLU_37938"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37938"/>
    <dbReference type="eggNOG" id="KOG0534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_4_1_1"/>
    <dbReference type="OMA" id="KAMMPDY"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000003">
        <property type="entry name" value="Nitrate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="9" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="11">
        <location>
            <begin position="487"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="598"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO98391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="866" mass="96270" checksum="001E21B60F8241A1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3M6</accession>
    <name>A4S3M6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peroxin-13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_26106</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxin-13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420118.1">
        <property type="nucleotide sequence ID" value="XM_001420081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3M6"/>
    <dbReference type="STRING" id="436017.A4S3M6"/>
    <dbReference type="GeneID" id="5003988"/>
    <dbReference type="Gramene" id="ABO98411">
        <property type="protein sequence ID" value="ABO98411"/>
        <property type="gene ID" value="OSTLU_26106"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26106"/>
    <dbReference type="eggNOG" id="ENOG502QSVT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056096_0_0_1"/>
    <dbReference type="OMA" id="GFWISFI"/>
    <dbReference type="OrthoDB" id="514567at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035463">
        <property type="entry name" value="Pex13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332:SF1">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="291" mass="28938" checksum="C3B5A3D0D5FC2052" modified="2007-05-15" version="1">MATPPPPKPWRAAAGAGETAVKSTPVADGSAVKPWDKPGAGQTPSAPVATVNNPTGTTATPESRAWETTNRGTSHGASPSGYAGTTYGGAPYGGNSMYGGYRGGAYGNSMYGGGYGGYGGGMYGGGMYGGGYGGGMYGGGYGGGYGGGMYGGYGGGMYGGHGGGMYGGGMYGQPPMGPYGPGGPPPGAPPLTGWQALMHSLSSVVHLFGKISFLVDENTQALHFFIMSLLQLLDRGGHLYGEMSRILLKAMGYPVPPRPPQQFGPPGGPGGFDNRGAPGAASFGDAWGSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3M9</accession>
    <name>A4S3M9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="5">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_94831</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420119.1">
        <property type="nucleotide sequence ID" value="XM_001420082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3M9"/>
    <dbReference type="STRING" id="436017.A4S3M9"/>
    <dbReference type="GeneID" id="5003990"/>
    <dbReference type="Gramene" id="ABO98412">
        <property type="protein sequence ID" value="ABO98412"/>
        <property type="gene ID" value="OSTLU_94831"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94831"/>
    <dbReference type="eggNOG" id="KOG4153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036923_0_0_1"/>
    <dbReference type="OMA" id="PAVNCTM"/>
    <dbReference type="OrthoDB" id="564183at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="339" mass="37170" checksum="A591977DCB4D890A" modified="2007-05-15" version="1">MIDVLNHARHHGYAIPAVNCTMSPVINACLEAAKKANAPMIVQFSNGGGYFMAGKGTSNADEKAAVAGCVAGAVMVRELAALYGVPVILHTDHCAKNLLPWFDGLLEANEAYFAKHGEPLFSSHMLDLSEEPIEENLEICKKYLARMKKINCFLEMEIGITGGEEDGVDNSDVAPEDLYSKPEEIYQVYEALQPIAPDFYSIAAAFGNVHGVYSPGNVKLTPKILANAQKFVKEKTGGDSDKPVYFVFHGGSEIREAVGYGVIKMNIDTDTQWSFWDGVKNYEAKNNAYLQGQIGNPEGAEKPNKKYYDPRAWIRSAEQATCDRLLAAYEDLNATNALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3X2</accession>
    <name>A4S3X2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_93364</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420168.1">
        <property type="nucleotide sequence ID" value="XM_001420131.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S3X2"/>
    <dbReference type="GeneID" id="5004034"/>
    <dbReference type="Gramene" id="ABO98461">
        <property type="protein sequence ID" value="ABO98461"/>
        <property type="gene ID" value="OSTLU_93364"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93364"/>
    <dbReference type="eggNOG" id="ENOG502SRG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_244577_0_0_1"/>
    <dbReference type="OMA" id="CGWCLEM"/>
    <dbReference type="OrthoDB" id="298344at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040221">
        <property type="entry name" value="CDCA7/CDA7L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31169:SF23">
        <property type="entry name" value="OS03G0572250 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31169">
        <property type="entry name" value="OS05G0300700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Zinc-finger" evidence="11">
        <location>
            <begin position="126"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="253"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="480"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="480"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="496"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1594" mass="170335" checksum="F409BB4AFFC6FF1A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S420</accession>
    <name>A4S420_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CG-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_26252</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 7" id="KW-0040">ANK repeat</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="CG-1" evidence="9">
        <location>
            <begin position="43"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="777"/>
            <end position="809"/>
        </location>
    </feature>
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        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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        </location>
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        <location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="433"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51437"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO98487.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1093" mass="120634" checksum="12CD1DE85A7AFA0A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4F1</accession>
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        </submittedName>
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        <name evidence="3" type="ORF">OSTLU_13022</name>
    </gene>
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            <taxon>Mamiellophyceae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="project" value="EnsemblPlants"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <end position="180"/>
        </location>
    </feature>
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        <location>
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            <end position="265"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="276" mass="29258" checksum="AB77A27754270772" modified="2007-05-15" version="1">MSRARSASDAGAEALAEALARHESRAARLSFAEEARVILDTNGCGALSTLGNQRAGVLAGFPCGSVAAYASDEDGLPIFALSALSQHARDARENGKATLTVTRAEFEDVSDGRVSMSGILTEVDAGEATARARARYLARHPGAFWVDFGDFAWYKMTEVVAIRIVGGFARAGSVTVEEYANARPDPVAAFSAPVCGHMNADHGDSLRDVVKHYVGVDVDSVEMRSIDALGMNCRVVKDGEKYACRLPFESAATGRKEVKDQIVLMTRNAAAAANAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4F5</accession>
    <name>A4S4F5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bacterial surface antigen (D15) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_50834</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Chloroplast outer membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420427.1">
        <property type="nucleotide sequence ID" value="XM_001420390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4F5"/>
    <dbReference type="STRING" id="436017.A4S4F5"/>
    <dbReference type="GeneID" id="5004326"/>
    <dbReference type="Gramene" id="ABO98720">
        <property type="protein sequence ID" value="ABO98720"/>
        <property type="gene ID" value="OSTLU_50834"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50834"/>
    <dbReference type="eggNOG" id="ENOG502QSQ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007664_2_0_1"/>
    <dbReference type="OMA" id="IKFRFVN"/>
    <dbReference type="OrthoDB" id="2013615at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009707">
        <property type="term" value="C:chloroplast outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF32">
        <property type="entry name" value="OUTER ENVELOPE PROTEIN 80, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="1" id="KW-1002">Plastid outer membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="5">
        <location>
            <begin position="250"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="580" mass="62538" checksum="2A6BE7B4DAC42B89" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4N5</accession>
    <name>A4S4N5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Digalactosyldiacylglycerol synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_17319</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO98758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420465.1">
        <property type="nucleotide sequence ID" value="XM_001420428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4N5"/>
    <dbReference type="STRING" id="436017.A4S4N5"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="GeneID" id="5004544"/>
    <dbReference type="Gramene" id="ABO98758">
        <property type="protein sequence ID" value="ABO98758"/>
        <property type="gene ID" value="OSTLU_17319"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17319"/>
    <dbReference type="eggNOG" id="ENOG502QQ73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011647_1_0_1"/>
    <dbReference type="OMA" id="ETFAHAM"/>
    <dbReference type="OrthoDB" id="44480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009707">
        <property type="term" value="C:chloroplast outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046481">
        <property type="term" value="F:digalactosyldiacylglycerol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019375">
        <property type="term" value="P:galactolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01635">
        <property type="entry name" value="Glycosyltransferase_GTB-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000067">
        <property type="entry name" value="Digalactosyldiacylglycerol synthase 1, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044525">
        <property type="entry name" value="DGDG1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46132">
        <property type="entry name" value="DIGALACTOSYLDIACYLGLYCEROL SYNTHASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46132:SF1">
        <property type="entry name" value="DIGALACTOSYLDIACYLGLYCEROL SYNTHASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13692">
        <property type="entry name" value="Glyco_trans_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="419"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="51073" checksum="F327AE7224891B19" modified="2007-05-15" version="1">MTGTAVNPLLRAAYLARRGIHDVTLVIPFLAPNEQKLVHPGMIFNTPEEQGEYVNKWVEERCGFKPQMKLSFYPGRYATDKYSIIPVGDLTSYIPGDRESDIAVLEEPEHLNWYHSGERWTDKFKHVVGIVHTNYLDYVRLEENGEIKEKALKFVNNVVSSVHCHKVIKLSDAVQEFPKSTTMNVHGVSPIFLDVGAKKAIEATKEKDVEMKRSKKPVFTKGAYFLGKVVWGKGYKELLDRVSEHNVSEDGRECPLELDVFGNGDDFAEVKSNAEKMKLPLHFHGRKDHAASDIHDYKVFVNPSLSDVVATTTAEALAMGKFVVCAKHPSNEFFSTFPNCLVYNTPQEFTKCVKQALTSEPAPLSAQDSYRLSWEAATDRFLDAAELSPRDVNPSLGDKAKETFAHAMHTTMNKIEPIRRATGAGNNTLKAPEKLDASWVPEPWDSSARDSNRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4P3</accession>
    <name>A4S4P3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S26 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420470.1">
        <property type="nucleotide sequence ID" value="XM_001420433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4P3"/>
    <dbReference type="STRING" id="436017.A4S4P3"/>
    <dbReference type="GeneID" id="5004547"/>
    <dbReference type="Gramene" id="ABO98763">
        <property type="protein sequence ID" value="ABO98763"/>
        <property type="gene ID" value="OSTLU_26480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26480"/>
    <dbReference type="eggNOG" id="KOG1568">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1527657_0_0_1"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053307">
        <property type="entry name" value="Mitochondrial_IM_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47040:SF1">
        <property type="entry name" value="MITOCHONDRIAL ATP-INDEPENDENT INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47040">
        <property type="entry name" value="OSJNBA0068L06.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="2">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="176" mass="18335" checksum="6E70F1227FE0C8EA" modified="2007-05-15" version="1">MTPTLRGGARDAPGPSSARGGSGTEYVLARRLAHPFRSAAIGDVVAFAHPSDATRTLIRRVSATEGDELVDAANASVYVVPKDHAWVTADADAETDSAKSAGRHEDSRSFGPVDAWALEWRVMYSMRSAVDHATVENSAAARAADAPVLEAELANAMEALGWDGEGEGEGEGGEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4W8</accession>
    <name>A4S4W8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_5051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420340.1">
        <property type="nucleotide sequence ID" value="XM_001420303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4W8"/>
    <dbReference type="STRING" id="436017.A4S4W8"/>
    <dbReference type="GeneID" id="5004519"/>
    <dbReference type="Gramene" id="ABO98633">
        <property type="protein sequence ID" value="ABO98633"/>
        <property type="gene ID" value="OSTLU_5051"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5051"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_7_35_1"/>
    <dbReference type="OrthoDB" id="10261027at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF11">
        <property type="entry name" value="OS09G0443600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="261" mass="29156" checksum="40058A20E691BAA8" modified="2007-05-15" version="1" fragment="single">GSSGEAFLASWRGARVVVKTMKLLHDDDAARRALARRAFVRECEIMARLRHPNVLAFYGANANGRDASVVCEYAPGGTLKQWLHENKGKKRSLSARLGMALDIARAFAYLESRTPRVMHRDLKPSNVFVSVDGRALVADFGLARFVAPRGEDLTGETGTYIYMAPEVIKSQHYDERADVFSYGILLYELVTGIEPYQPHHFTGIQIATAVADRAFRPKIPDSTHAGLTAIIEMCWQQDASNRPSFERVRESMETMVPDILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S574</accession>
    <name>A4S574_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420722.1">
        <property type="nucleotide sequence ID" value="XM_001420685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S574"/>
    <dbReference type="GeneID" id="5004789"/>
    <dbReference type="Gramene" id="ABO99015">
        <property type="protein sequence ID" value="ABO99015"/>
        <property type="gene ID" value="OSTLU_26661"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26661"/>
    <dbReference type="HOGENOM" id="CLU_832583_0_0_1"/>
    <dbReference type="OrthoDB" id="10494831at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="334" mass="35687" checksum="E08224D921E21BBC" modified="2007-05-15" version="1">MTTPRATTRATTRSTAARAQTREIFASTTRVARARGRATTVVRAATITIEEAGKVLSHVVHATTVEPDYRVLKLGLSLSNVTDPGAVTDVVAAKTGKEAKSVAWVVERASASEGKRDVDEFWANVNAEAIRQLFPSVTPGNETAALLRSLYFKAERAALSECVGGLATCALLRKLTQTRALVARDGRVVRDVRAMKAPRPLKGGLFANPEILYHGEKGPKSRRNLLTHEFDESIAAKLGTRAAFHQTAIVRIDDAPDANDDAQVWLEIDIAGPALDNYEFSDDGAVPLCVASVSAAERAGWTTTVDELLASSSADDIAAADAFADRAYSILVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Q0</accession>
    <name>A4S5Q0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pheophorbide a oxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_5015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420810.1">
        <property type="nucleotide sequence ID" value="XM_001420773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Q0"/>
    <dbReference type="STRING" id="436017.A4S5Q0"/>
    <dbReference type="GeneID" id="5004909"/>
    <dbReference type="Gramene" id="ABO99103">
        <property type="protein sequence ID" value="ABO99103"/>
        <property type="gene ID" value="OSTLU_5015"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5015"/>
    <dbReference type="eggNOG" id="ENOG502QS20">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1242897_0_0_1"/>
    <dbReference type="OMA" id="IAIEHEI"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010277">
        <property type="term" value="F:chlorophyllide a oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013626">
        <property type="entry name" value="PaO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF19">
        <property type="entry name" value="CHLOROPHYLLIDE A OXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08417">
        <property type="entry name" value="PaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Pheophorbide a oxygenase" evidence="2">
        <location>
            <begin position="98"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="223" mass="25096" checksum="3E31BC535C77E126" modified="2007-05-15" version="1" fragment="single">RDGLVMVWPSMNCGPTEELPSHFAAPEGYTIHAELIIEDVPVEHGLLMENLLDLAHAPFTHTGTFAKGWGVPNMVKFASRKLRKDGDGWKPYPIDMKFLAPCMVDSHIGLAQAGAVGKGAQFKEGVSALECEKHLHQLHVCLPSTPGHTRLLYRMSLDFASWAQYVPGIEYIWTEMANQVLGEDLRLVTGQQDRMQRGARVWAHPVAYDKLGLHYRRWRNVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5S5</accession>
    <name>A4S5S5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420822.1">
        <property type="nucleotide sequence ID" value="XM_001420785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5S5"/>
    <dbReference type="GeneID" id="5004921"/>
    <dbReference type="Gramene" id="ABO99115">
        <property type="protein sequence ID" value="ABO99115"/>
        <property type="gene ID" value="OSTLU_17627"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17627"/>
    <dbReference type="HOGENOM" id="CLU_1087377_0_0_1"/>
    <dbReference type="OrthoDB" id="10607973at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="26994" checksum="4369E6FAFCE9B19B" modified="2007-05-15" version="1">MFGRASDSARTVADAVTRAPSASASDGVAAAWTRARETATKALGGTTTPTTLGGARATTERAARATSARSTTMMPKIGLRGYFIAGAVTGCAVAYALGPERCKRAARRCVDKCEDAMKRAMAIVADAFERVFSDDVRAAMEDAISRCRDAIGGVGPKLAPMLKSSTENLHALLETSVERTTAYTGKMTAFVGDFSEKYVAVAASAIKARAIDGYAVARVGFRDVVDKSFVGFDAARRRAREFLATVVDAIKPSKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Z3</accession>
    <name>A4S5Z3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_26932</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420857.1">
        <property type="nucleotide sequence ID" value="XM_001420820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Z3"/>
    <dbReference type="STRING" id="436017.A4S5Z3"/>
    <dbReference type="GeneID" id="5004896"/>
    <dbReference type="Gramene" id="ABO99150">
        <property type="protein sequence ID" value="ABO99150"/>
        <property type="gene ID" value="OSTLU_26932"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26932"/>
    <dbReference type="eggNOG" id="ENOG502QT7M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_761612_0_0_1"/>
    <dbReference type="OMA" id="MADERFW"/>
    <dbReference type="OrthoDB" id="551907at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025756">
        <property type="entry name" value="Myb_CC_LHEQLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046955">
        <property type="entry name" value="PHR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31499:SF43">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR APL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31499">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR PHL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14379">
        <property type="entry name" value="Myb_CC_LHEQLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="119"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="MYB-CC type transcription factor LHEQLE-containing" evidence="6">
        <location>
            <begin position="302"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="364" mass="38517" checksum="5B64BF1F6A2BFD35" modified="2007-05-15" version="1">MADERFWPLFEGLAGAGDGALDGAVDDTLDWLDDVIVRGATSGRVEDEDALGEDAAEDDDDARDGTRANDGRGGGRKRARASGDARASTSGQEKRAKANAGRGKEGNATRGRNGRGGARLRWTPELHREFINAVNQLGGLELATPKGIMHIMAMSGMTIQHIKSHLQKYRLQEGAGGSRGAELDAEADRERRAMIKRARVQQQAEMKQRASEADLMGLDVASAAPMGSGLSSDPPSTPVTTAQLSELLNSTSAMKAKTLGSEGKIHALDAILAQALKPAATLSDEAAAAVVSAELIEDMPHVGHALLKQLEMQKQLHDQLIAQRRLQTAIEEHGKYLASILAQEVSGKTKPPEAALGDDAVDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6G9</accession>
    <name>A4S6G9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420941.1">
        <property type="nucleotide sequence ID" value="XM_001420904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6G9"/>
    <dbReference type="GeneID" id="5005147"/>
    <dbReference type="Gramene" id="ABO99234">
        <property type="protein sequence ID" value="ABO99234"/>
        <property type="gene ID" value="OSTLU_27116"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27116"/>
    <dbReference type="eggNOG" id="ENOG502S8DQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1201259_0_0_1"/>
    <dbReference type="OMA" id="FSSDMYH"/>
    <dbReference type="OrthoDB" id="10266005at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35716:SF1">
        <property type="entry name" value="OS05G0574700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35716">
        <property type="entry name" value="OS05G0574700 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="22552" checksum="9B83FA857E3D37CD" modified="2007-05-15" version="1">MASAEEILMQVIDRREFKPTSEECPFCREARVKENGSKCLGICRNPQNVPGPLVYPHAMQTWEDAVDCILWAMRDISTPRTDHGVQVMWEYAVEHGNMERSRFFGFSSDMYHFDHFIGKALNTYDAFVRNTGHEITQVSTMEDGRTRVDVRVKDRVGEETEWIFIMVRRTFGKYEGCIQAHRIVRADFPHLGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6K3</accession>
    <name>A4S6K3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ENT family transporter: nucleoside</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_27151</name>
        <name evidence="9" type="ORF">OSTLU_29758</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420959.1">
        <property type="nucleotide sequence ID" value="XM_001420922.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422935.1">
        <property type="nucleotide sequence ID" value="XM_001422898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6K3"/>
    <dbReference type="STRING" id="436017.A4S6K3"/>
    <dbReference type="GeneID" id="5004964"/>
    <dbReference type="GeneID" id="5006993"/>
    <dbReference type="Gramene" id="ABO99252">
        <property type="protein sequence ID" value="ABO99252"/>
        <property type="gene ID" value="OSTLU_27151"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01294">
        <property type="protein sequence ID" value="ABP01294"/>
        <property type="gene ID" value="OSTLU_29758"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27151"/>
    <dbReference type="KEGG" id="olu:OSTLU_29758"/>
    <dbReference type="eggNOG" id="KOG1479">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021611_1_0_1"/>
    <dbReference type="OMA" id="WVYWGIA"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034257">
        <property type="term" value="F:nicotinamide riboside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF88">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01130">
        <property type="entry name" value="DERENTRNSPRT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="33411" checksum="DEBADE986E4244CF" modified="2007-05-15" version="1">MDVVFAQTLGVIVVVGLATAVAQSGGFALASRLPPEFAQGAMSGQAVSGVVVSLVALATTAYGGGSVSSSSSAKGAQAYFYVAAAVVLGCAATAARLDKTPAFEELTGVERHRDGRRSEMNALLRDDDVDEYDSDVEGAPLRASTGVEDFGDESRDYRLAVALTFIASLCAFPAITSSIESSHGAMGAFWSPVLFLLFNLGDFLGRHLAGMYPKTPPRGASLRRAATLRFAFIPFLAACNVTTPNWRVPTVFASDFFPFLFISALAVTNGWLASVAMMHGASRAPLSKRQAEGVVLSFALVAGIFLGTALSLFIVFILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6W2</accession>
    <name>A4S6W2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27263</name>
        <name evidence="4" type="ORF">OSTLU_29648</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421013.1">
        <property type="nucleotide sequence ID" value="XM_001420976.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422882.1">
        <property type="nucleotide sequence ID" value="XM_001422845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6W2"/>
    <dbReference type="GeneID" id="5004934"/>
    <dbReference type="GeneID" id="5006851"/>
    <dbReference type="Gramene" id="ABO99306">
        <property type="protein sequence ID" value="ABO99306"/>
        <property type="gene ID" value="OSTLU_27263"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01241">
        <property type="protein sequence ID" value="ABP01241"/>
        <property type="gene ID" value="OSTLU_29648"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27263"/>
    <dbReference type="KEGG" id="olu:OSTLU_29648"/>
    <dbReference type="HOGENOM" id="CLU_2162638_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="111" mass="11909" checksum="0CB60BCD122C0764" modified="2007-05-15" version="1">MPTSLTRAGARATPSTLGVDPEDVLHPRVRDLLHGDVVRVGAPTPSVMKQRLRNKLWKLVVLAIASVVLWALQGARQAREGAWARGEGVVEPMAVRFARKGAFGGGAKIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4S707</accession>
    <name>A4S707_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421189.1">
        <property type="nucleotide sequence ID" value="XM_001421152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S707"/>
    <dbReference type="GeneID" id="5005376"/>
    <dbReference type="Gramene" id="ABO99482">
        <property type="protein sequence ID" value="ABO99482"/>
        <property type="gene ID" value="OSTLU_27309"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27309"/>
    <dbReference type="HOGENOM" id="CLU_2337409_0_0_1"/>
    <dbReference type="OMA" id="IAEMTWE"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="98" mass="10173" checksum="03EA8E82796770B6" modified="2007-05-15" version="1">MPQPLGKPLSEVEAEEARVAEASGRRRNGSDDARAGREGMAETPPWWMTTVSAIVLVLLTWSSVGLGSVDRVAEAPRLTPDEIERFRAGGGGGGGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7F0</accession>
    <name>A4S7F0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine transferase subunit ALG14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_43228</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ALG14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421442.1">
        <property type="nucleotide sequence ID" value="XM_001421405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7F0"/>
    <dbReference type="STRING" id="436017.A4S7F0"/>
    <dbReference type="GeneID" id="5005306"/>
    <dbReference type="Gramene" id="ABO99735">
        <property type="protein sequence ID" value="ABO99735"/>
        <property type="gene ID" value="OSTLU_43228"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43228"/>
    <dbReference type="eggNOG" id="KOG3339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064541_2_0_1"/>
    <dbReference type="OMA" id="GTCCIIT"/>
    <dbReference type="OrthoDB" id="17098at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043541">
        <property type="term" value="C:UDP-N-acetylglucosamine transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013969">
        <property type="entry name" value="Oligosacch_biosynth_Alg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154:SF4">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08660">
        <property type="entry name" value="Alg14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673100" description="UDP-N-acetylglucosamine transferase subunit ALG14" evidence="8">
        <location>
            <begin position="23"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="215" mass="23311" checksum="9E61C405A3696B76" modified="2007-05-15" version="1">MPPRSLLALLALANVALWIARAATRAFDKSALRGRRARALVVLGSGGHTAEMLRILRDARTLDRLDVAAYVVASTDARSADRALTFERSRRGARGEARVLTIGRAREVGQRWTTSAATTARACAAAIAIVARVKPDVVICNGPGTCVPIVLAAMARRALGWRTPATVFVESACRARTLSLTGKIFYHLRCVDRVCVMWERAHAAYPRSTFVGRAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S858</accession>
    <name>A4S858_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421567.1">
        <property type="nucleotide sequence ID" value="XM_001421530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S858"/>
    <dbReference type="STRING" id="436017.A4S858"/>
    <dbReference type="GeneID" id="5005605"/>
    <dbReference type="Gramene" id="ABO99860">
        <property type="protein sequence ID" value="ABO99860"/>
        <property type="gene ID" value="OSTLU_18283"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18283"/>
    <dbReference type="eggNOG" id="KOG4380">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1024291_0_0_1"/>
    <dbReference type="OMA" id="MQEYTAD"/>
    <dbReference type="OrthoDB" id="567477at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019265">
        <property type="entry name" value="RTRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15924">
        <property type="entry name" value="CLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10036">
        <property type="entry name" value="RLL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="274" mass="28926" checksum="6A1FB20AD24752B3" modified="2007-05-15" version="1">MSRARPRATLDDALRARALTVLGAPASALECSTSASALAALAEFLEDTVIRALPADQRDGLRRARTADARGVRDALTAYGEHLEPAIEALGEGALDAVADELLERATALKHADASPSAARDDVEAIERSSKRLKLFSRDADEVSGALASDAGWEALTRLATALGAETNGTGGGRDPLDACVLLERCVVAQERFVTAFASASGRETARNPPKLEDMPSGVGLNGDAEVERAVAVARLLHVNDLRRLQSEVDAFLVAMQEYTADPKTDSRIGKVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S885</accession>
    <name>A4S885_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HTA3504</name>
        <name evidence="13" type="ORF">OSTLU_13304</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421582.1">
        <property type="nucleotide sequence ID" value="XM_001421545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S885"/>
    <dbReference type="STRING" id="436017.A4S885"/>
    <dbReference type="GeneID" id="5005856"/>
    <dbReference type="Gramene" id="ABO99875">
        <property type="protein sequence ID" value="ABO99875"/>
        <property type="gene ID" value="OSTLU_13304"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13304"/>
    <dbReference type="eggNOG" id="KOG1756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062828_3_0_1"/>
    <dbReference type="OMA" id="HYSKRVG"/>
    <dbReference type="OrthoDB" id="496320at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000009">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="11">
        <location>
            <begin position="8"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="12">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="129" mass="13607" checksum="FE4ECCB6ABCAD77D" modified="2007-05-15" version="1">MSGRGKGKSGKKATSRSAKAGLQFPVGRVARYLKAGKYATRVGAGAPVYLAAVMEYLCAEVLELAGNAARDNKKSRVVPRHIQLAIRNDEELSKLLGTVTIAAGGVLPNIHSVLLPKKSKKSGSASQEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8F5</accession>
    <name>A4S8F5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1826 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421610.1">
        <property type="nucleotide sequence ID" value="XM_001421573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8F5"/>
    <dbReference type="GeneID" id="5005698"/>
    <dbReference type="Gramene" id="ABO99903">
        <property type="protein sequence ID" value="ABO99903"/>
        <property type="gene ID" value="OSTLU_18357"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18357"/>
    <dbReference type="eggNOG" id="ENOG502SBZ6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1032044_0_0_1"/>
    <dbReference type="OrthoDB" id="539419at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014955">
        <property type="entry name" value="DUF1826"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08856">
        <property type="entry name" value="DUF1826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="29438" checksum="316E3F53410B8CA7" modified="2007-05-15" version="1">MSRACASSRVALARASRAPTRKRALDRSTRSRAVATRDDARADVESDASALSRALESIRDADVNVVVVERDDARKRFVERESLVEALRASAAFERAVTFRKAPTVEETARALAVADNALARDIATCVRAFVNVVPGADRGVKVTLSLLRSTLCSRLHVDHTSARMMVTFYGRGTEICDARTSAAIAKANADGGNFVTDALKTLAEKFAPPREISTCDVALLKGERWTYADGSTSKGKAIVHRSPLIDENEWRLTLKVDVVNFGCECEEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8M2</accession>
    <name>A4S8M2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421790.1">
        <property type="nucleotide sequence ID" value="XM_001421753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8M2"/>
    <dbReference type="STRING" id="436017.A4S8M2"/>
    <dbReference type="GeneID" id="5005757"/>
    <dbReference type="Gramene" id="ABP00084">
        <property type="protein sequence ID" value="ABP00084"/>
        <property type="gene ID" value="OSTLU_27898"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27898"/>
    <dbReference type="HOGENOM" id="CLU_2489857_0_0_1"/>
    <dbReference type="OMA" id="MGFLTRW"/>
    <dbReference type="OrthoDB" id="496273at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035204">
        <property type="entry name" value="NDUFB11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17250">
        <property type="entry name" value="NDUFB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="76" mass="8740" checksum="DBB91B87305AF540" modified="2007-05-15" version="1">MGFLTRFIASGIDDGVERQRALEKHLEKTSAKCATLKDNWDQPTKSDRYWLREKSQLAYADANQTGDDVPGRRPVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8V9</accession>
    <name>A4S8V9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_37765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="8">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421955.1">
        <property type="nucleotide sequence ID" value="XM_001421918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8V9"/>
    <dbReference type="SMR" id="A4S8V9"/>
    <dbReference type="STRING" id="436017.A4S8V9"/>
    <dbReference type="GeneID" id="5006120"/>
    <dbReference type="Gramene" id="ABP00249">
        <property type="protein sequence ID" value="ABP00249"/>
        <property type="gene ID" value="OSTLU_37765"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37765"/>
    <dbReference type="eggNOG" id="ENOG502S3RJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082632_1_1_1"/>
    <dbReference type="OMA" id="FICMASS"/>
    <dbReference type="OrthoDB" id="1885901at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000014">
        <property type="entry name" value="Ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010241">
        <property type="entry name" value="Fd_pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02008">
        <property type="entry name" value="fdx_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112">
        <property type="entry name" value="FERREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112:SF3">
        <property type="entry name" value="FERREDOXIN-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="9">
        <location>
            <begin position="30"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="12901" checksum="E5CCA228420F3B07" modified="2007-05-15" version="1">MSVTAAPVASFAGARRSSAAVARRSTIARFQVTLETPEGAQAIECADDTYILDAAEEAGIDLPYSCRAGACSSCAGKVTAGSIDQSDQSFLDDDQMGNGFVLTCVAYPTSDCTVKTHMEEELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S995</accession>
    <name>A4S995_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_28125</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="14">Binds 1 heme c group covalently per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422024.1">
        <property type="nucleotide sequence ID" value="XM_001421987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S995"/>
    <dbReference type="STRING" id="436017.A4S995"/>
    <dbReference type="GeneID" id="5005926"/>
    <dbReference type="Gramene" id="ABP00318">
        <property type="protein sequence ID" value="ABP00318"/>
        <property type="gene ID" value="OSTLU_28125"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28125"/>
    <dbReference type="eggNOG" id="KOG3052">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040334_1_0_1"/>
    <dbReference type="OMA" id="WVKKFKW"/>
    <dbReference type="OrthoDB" id="5925at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000002">
        <property type="entry name" value="Cytochrome c1, heme protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000003">
        <property type="entry name" value="Cytochrome c1, heme protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021157">
        <property type="entry name" value="Cyt_c1_TM_anchor_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="CYTOCHROME C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266:SF3">
        <property type="entry name" value="CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81496">
        <property type="entry name" value="Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="17">
        <location>
            <begin position="34"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602326-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABP00318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="251" mass="27684" checksum="0C3CA841E0387814" modified="2007-05-15" version="1">MTAAVAVADEAEHGLALPRYEWPHDGLFSSYDHASVRRGHQVYTQVCAACHSLNQIAYRNLVGVAYTEAEAKALAEEVEVRDGPDDTGEMFDRPGKLSDGIPAPYANEEGARFANNGAYPPDLSLMTKARHDGINYVFALLLGYREPPAGVEVPGGMYYNPYFPGGFIAMPKMLVDGGVEYDDGTPATETQMAKDVTTFLAWAAEPEMDDRKLMGAKWIFALSLVAVQAVYYKRWAWSHLKSRKLVVDVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9W4</accession>
    <name>A4S9W4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28337</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422242.1">
        <property type="nucleotide sequence ID" value="XM_001422205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9W4"/>
    <dbReference type="GeneID" id="5006195"/>
    <dbReference type="Gramene" id="ABP00559">
        <property type="protein sequence ID" value="ABP00559"/>
        <property type="gene ID" value="OSTLU_28337"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28337"/>
    <dbReference type="eggNOG" id="ENOG502QUWR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_941321_0_0_1"/>
    <dbReference type="OMA" id="HRICGTA"/>
    <dbReference type="OrthoDB" id="497462at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051598">
        <property type="entry name" value="TSUP/Inactive_protease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN MJ0441-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701:SF2">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN YJNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="30519" checksum="A2594D81E542F5D6" modified="2007-05-15" version="1">MASPHLARASSLVRGAFTVASGGFAGSVSAVTGLGGAVVFIPALSKLGYEARHIVGTAVVAVTGATAAGSFAYAQNGVSDVPAAVTVGCVGAACTPVGQLLAKRLSGKTLRKMLGGALILCSPSAMLKKHAEEVEEAGKDAKEGWAIKREREPATNTWEIVRNQFLDRHDKWGGWMEALRGEREMLALGVACGLLQGTVGVGGGVLVSAYLTGMTDMEVHRICGTALLATVLTNLAVSTAHFRNGNVKFRSAALLAGSAMACSYLVAKNLSLQIPEAHVKQFIVVALISSGVSMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Z3</accession>
    <name>A4S9Z3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_6846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422152.1">
        <property type="nucleotide sequence ID" value="XM_001422115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9Z3"/>
    <dbReference type="STRING" id="436017.A4S9Z3"/>
    <dbReference type="GeneID" id="5006313"/>
    <dbReference type="Gramene" id="ABP00469">
        <property type="protein sequence ID" value="ABP00469"/>
        <property type="gene ID" value="OSTLU_6846"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6846"/>
    <dbReference type="eggNOG" id="KOG1552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_5_2_1"/>
    <dbReference type="OMA" id="MCKSLAY"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22994" checksum="77084FD6625A9CE6" modified="2007-05-15" version="1" fragment="single">RAPAERVVIHCHANACDIGHIHSLCARDAECWRANVLLVEYPGYGTSEGVAYERAVDRHVAAAYVYVTEECGVNPRDVVVLGRSLGTGPATKLAAAVERLDGAQLGGVILHSPFTSVKQAGLVLLGQIAHIMDDRWDNREWVRAYKARTLIVHAIEDEVVPFAHAQELDEIRRAAGLHCKLHSTHGTHNYFSYYRDYLQPILEFIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA46</accession>
    <name>A4SA46_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28493</name>
        <name evidence="5" type="ORF">OSTLU_33729</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422283.1">
        <property type="nucleotide sequence ID" value="XM_001422246.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422349.1">
        <property type="nucleotide sequence ID" value="XM_001422312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA46"/>
    <dbReference type="STRING" id="436017.A4SA46"/>
    <dbReference type="GeneID" id="5006365"/>
    <dbReference type="GeneID" id="5006406"/>
    <dbReference type="Gramene" id="ABP00600">
        <property type="protein sequence ID" value="ABP00600"/>
        <property type="gene ID" value="OSTLU_33729"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP00666">
        <property type="protein sequence ID" value="ABP00666"/>
        <property type="gene ID" value="OSTLU_28493"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28493"/>
    <dbReference type="KEGG" id="olu:OSTLU_33729"/>
    <dbReference type="eggNOG" id="KOG0747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_14_1"/>
    <dbReference type="OMA" id="KLIPLMC"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="4"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="360" mass="40569" checksum="979276E787EE703C" modified="2007-05-15" version="1">MRILLTGGAGFIGSHVAERLASRHPEYTIVILDKLDYCSSLKNLERAKECANVRFVKGDVRSFDLLSYVLQSERIDTVMHFAAQSHVDNSFGNSYEFTKNNIEGTHALLEACVRAQKTEIRRFLHVSTDEVYGENLMDSNTEHASLLTPTNPYAATKAGAEMLVMAYGRSYGLPYIITRGNNVYGPNQYPEKAIPKFSILAKRGEKISIHGDGDATRSYMHVDDASSAFDVILHRGTTAQIYNIGSREERTILSVARDVCKLLDRDPETTIEHVSDRAFNDRRYFIDCSKLLALGWRQEKSWDVGLAETVRWYSNNDLSAYWGEFSPALRPHPSASADGRRRSLEFDFTNELDDCTTLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAA4</accession>
    <name>A4SAA4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.1.3.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_25793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.14" evidence="3"/>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422307.1">
        <property type="nucleotide sequence ID" value="XM_001422270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAA4"/>
    <dbReference type="GeneID" id="5006372"/>
    <dbReference type="Gramene" id="ABP00624">
        <property type="protein sequence ID" value="ABP00624"/>
        <property type="gene ID" value="OSTLU_25793"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25793"/>
    <dbReference type="eggNOG" id="ENOG502R8PF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041674_1_0_1"/>
    <dbReference type="OrthoDB" id="10265086at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03786">
        <property type="entry name" value="GTB_UDP-GlcNAc_2-Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174:SF2">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-N-acetylglucosamine 2-epimerase" evidence="5">
        <location>
            <begin position="39"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="355"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="389" mass="42971" checksum="90366D765E91A3DA" modified="2007-05-15" version="1">MKDIESERFDRTAYSAEIKIAIVFGTRPEAVKMAPVIQAVARSSTLSAILISTGQHKQMLEQVLRQFSLQDKIQHELALMKPNQQLAELTSSAVRAVDGVLRSSKPDAVLVQGDTTTAFITSLAAFYLKIPVGHIEAGLRTRDIYSPFPEEVNRQCISVMATYHFAPTEHAAKNLYDEGRRTNVFTTGNTVTEPSDRVIELSKVVKTVSTLRDVRLLLLTAHRRENLGEPILNIFTSIEKLLQEYPDVVVIYPIHLNPMSDHAPPTTTHLRRLLIVPPLDHADLLFMMKESFFVMTDSGGIQEEAVTLGKPVLVLRDTTERPEGVLAGAAKLVGHGAESIYTEAASLLKDPDSYRSMSGSKKTYGDGNAAGNIVAKEKQKERRGTVPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAD6</accession>
    <name>A4SAD6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phytanoyl-CoA dioxygenase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_94008</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422368.1">
        <property type="nucleotide sequence ID" value="XM_001422331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAD6"/>
    <dbReference type="GeneID" id="5006474"/>
    <dbReference type="Gramene" id="ABP00685">
        <property type="protein sequence ID" value="ABP00685"/>
        <property type="gene ID" value="OSTLU_94008"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94008"/>
    <dbReference type="eggNOG" id="ENOG502QV4U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057974_0_0_1"/>
    <dbReference type="OMA" id="GYRLDHN"/>
    <dbReference type="OrthoDB" id="2328924at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="37717" checksum="208E2BA87ED902EE" modified="2007-05-15" version="1">MSRALLTRATRAIARSRARTCHDQIALDVPPSSVVTASDKFWFDTNGFLILRNAFDKSAIRAMNAAIDARIDDPTIERKGNLRLTKRGGPLSGDGTTGRKDVAGFLGWPRGEREAFRDVLTHERLVPYLHEFCGRGYRLDHNPLCIAQDPGAEGFEFHGGSATEDGRWNWPLAYAVEQGQIRCNLLAVAVPLTDVKEGEGGFVIVRGSHKSRFPAPAAVKRYEDGPEHGYAPALNAGDAVLFSEATTHGTLAWKGKSQRRTLIYRFSPATNAYGRGYSPEWPENWTDGMTPAQLATLQPPYHPRLDRDAVADDGINVIKPAARETFKVEFDEKIFKSKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAM0</accession>
    <name>A4SAM0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPP0</name>
        <name evidence="8" type="ORF">OSTLU_29307</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Ribosomal protein P0 is the functional equivalent of E.coli protein L10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422456.1">
        <property type="nucleotide sequence ID" value="XM_001422419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAM0"/>
    <dbReference type="STRING" id="436017.A4SAM0"/>
    <dbReference type="GeneID" id="5006514"/>
    <dbReference type="Gramene" id="ABP00773">
        <property type="protein sequence ID" value="ABP00773"/>
        <property type="gene ID" value="OSTLU_29307"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29307"/>
    <dbReference type="eggNOG" id="KOG0815">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053173_1_1_1"/>
    <dbReference type="OMA" id="DMNPFKL"/>
    <dbReference type="OrthoDB" id="10259902at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="112"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="313" mass="33346" checksum="52C9FE7EC10CEED2" modified="2007-05-15" version="1">MPSAAQLKKQGYAERVHKLLDNYDTALLVHADNVGSKQFMDIRASIRPESVVLMGKNTLMRKCISNYCAAKGDDTWMILSNKLVGNVGIIFTKGDLLDVRKKIQQFVVPAPARVGAIAPVEVVVPAGPTGMEPSQTSFFQTLNIATKINKGTIEILNDIVVLQPGDRVSSSAAALLGKMKFTPFTYGLIVMEVYDKGAMYPSAVLDITNETLEKKFMSGVAQVASLSLASGYPTLASVPHSIVNAYKNVLAISIGTDYTFELAQKVKDYLANPGAFASAAPAAGGDAAAGGAAKAAAVEEEEEEAEMDFDLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAU2</accession>
    <name>A4SAU2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">OSTLU_29380</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 22">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422663.1">
        <property type="nucleotide sequence ID" value="XM_001422626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAU2"/>
    <dbReference type="STRING" id="436017.A4SAU2"/>
    <dbReference type="GeneID" id="5006557"/>
    <dbReference type="Gramene" id="ABP00980">
        <property type="protein sequence ID" value="ABP00980"/>
        <property type="gene ID" value="OSTLU_29380"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29380"/>
    <dbReference type="eggNOG" id="KOG0317">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041707_0_0_1"/>
    <dbReference type="OMA" id="YCDVVQL"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010381">
        <property type="term" value="P:peroxisome-chloroplast membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009853">
        <property type="term" value="P:photorespiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd16527">
        <property type="entry name" value="RING-HC_PEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF0">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="19">
        <location>
            <begin position="305"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABP00980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="37700" checksum="AEB82283DB515078" modified="2007-05-15" version="1">MATRSRGFPRAARPDVVRAAQKDETHAAATAERLHDACARALGPRLSVRWNRALRACGRAAYPALTYLSGRATLGEEYCDLASGDARGRKSSARALWTRFVIDAFGEEIARELRGCVVRNHERGVGLGGGETSAATRAMDASARTALALVGRRVERGMGDETTSHGQAMIDARGGFANAAHLALFYANGEYYDWSCRASGTRRAFTGAYAGEERPSYALLGVFVAFQLAVVTCENVASFARGGGSSETSGAPSVGARVLESDGSPAIEAAIVASPRLDVFGNPVDEGASASRKSKSTSPLIAAKCALCLSPRESPTATPCGHVFCWRCIAGWASKKPECPLCRAPTTPQSLVPLSNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAV1</accession>
    <name>A4SAV1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422667.1">
        <property type="nucleotide sequence ID" value="XM_001422630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAV1"/>
    <dbReference type="GeneID" id="5006562"/>
    <dbReference type="Gramene" id="ABP00984">
        <property type="protein sequence ID" value="ABP00984"/>
        <property type="gene ID" value="OSTLU_29388"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29388"/>
    <dbReference type="HOGENOM" id="CLU_2982468_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="58" mass="6453" checksum="92003B84CABF5B72" modified="2007-05-15" version="1">MAEMTVDEGLGRARDARRDAATREVEAANALREVETSLAEIERGIRELLELELAERAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB08</accession>
    <name>A4SB08_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422534.1">
        <property type="nucleotide sequence ID" value="XM_001422497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB08"/>
    <dbReference type="STRING" id="436017.A4SB08"/>
    <dbReference type="GeneID" id="5006751"/>
    <dbReference type="Gramene" id="ABP00851">
        <property type="protein sequence ID" value="ABP00851"/>
        <property type="gene ID" value="OSTLU_29447"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29447"/>
    <dbReference type="eggNOG" id="ENOG502QQBA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056488_0_0_1"/>
    <dbReference type="OMA" id="PEIDKWE"/>
    <dbReference type="OrthoDB" id="498072at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF261">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="27171" checksum="883D0EE5BEF75157" modified="2007-05-15" version="1">MCPGLEFTSDVIEAERNGEACAGGMFVPNGVVVDAPRYLTALWDACGILASRGAAGTRATLRIAEVDDVKALLDEFDQVALCCGAGVAALFDFETIPVSLQGGHVLELKPEGLSVGILGTTYVAPLGDDRAMIGPTKEYDATPEDCARSGVVDDVDDERSARAISELRELGARAYPPCANWEFLRLKYGVRANPPRTHAGALPLAGSVHVDGRRCWFAAGLGARGLIYHGLLADWLSSAILDDDINAIPVDVRRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB65</accession>
    <name>A4SB65_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TFIIF beta subunit HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_6696</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422722.1">
        <property type="nucleotide sequence ID" value="XM_001422685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB65"/>
    <dbReference type="STRING" id="436017.A4SB65"/>
    <dbReference type="GeneID" id="5006621"/>
    <dbReference type="Gramene" id="ABP01039">
        <property type="protein sequence ID" value="ABP01039"/>
        <property type="gene ID" value="OSTLU_6696"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6696"/>
    <dbReference type="eggNOG" id="KOG2905">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094779_0_0_1"/>
    <dbReference type="OMA" id="PIADNCY"/>
    <dbReference type="OrthoDB" id="498282at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000035">
        <property type="entry name" value="General transcription factor IIF subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003196">
        <property type="entry name" value="TFIIF_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040450">
        <property type="entry name" value="TFIIF_beta_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02270">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIF beta subunit HTH" evidence="8">
        <location>
            <begin position="178"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="241" mass="27488" checksum="5ED889CFAF99CF5C" modified="2007-05-15" version="1" fragment="single">LDTTRGDRNAWLVKVPKFVSRVFHEAAAASKQAMADDDDMDTDTKEEDEPAIGTVRHMTHAIMELTGKEANGVPKQYILANQPSDMPMRVFSDVREGTTSGQADITLEAKVDLKLDMRPTSIDDVDYHRVSKDRMIQAQTKTRVTQSSSEMRFAPLPKARNLIRFTDAASNKKEKKERMEKKALENVLFGLFERQPYWSLKQLILETKQPVDWLKTNLGEIALLTRRGPNMGLWGLKPEWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB95</accession>
    <name>A4SB95_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422579.1">
        <property type="nucleotide sequence ID" value="XM_001422542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB95"/>
    <dbReference type="STRING" id="436017.A4SB95"/>
    <dbReference type="GeneID" id="5006793"/>
    <dbReference type="Gramene" id="ABP00896">
        <property type="protein sequence ID" value="ABP00896"/>
        <property type="gene ID" value="OSTLU_29530"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29530"/>
    <dbReference type="eggNOG" id="KOG1996">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_835195_0_0_1"/>
    <dbReference type="OMA" id="HACFYDE"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010017">
        <property type="term" value="P:red or far-red light signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010099">
        <property type="term" value="P:regulation of photomorphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010029">
        <property type="term" value="P:regulation of seed germination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010119">
        <property type="term" value="P:regulation of stomatal movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009637">
        <property type="term" value="P:response to blue light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010218">
        <property type="term" value="P:response to far red light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010114">
        <property type="term" value="P:response to red light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000382">
        <property type="entry name" value="G-patch domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031066">
        <property type="entry name" value="Splicing_factor_SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G-patch" evidence="8">
        <location>
            <begin position="169"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="22"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="146"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR031066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="333" mass="36762" checksum="50833DFDABA9F4D5" modified="2007-05-15" version="1">MRAKGAIGGKAGVLRAQANALRAARSRTLRDAEARRAESKKRARERKEDSRGGEDEVKTIEVAVASDEEETDDVDDGYDPAAPNDYERTLAERAERARRRRDLNANEELRKELESKRKAMESQRSAMDREEVLGVDGREARRRRLAMGRDAGASRDTNSASGAQKANKGKSAAEKMMEKMGWTKGRGLGKSEQGMTTPLEVRKDSATSGKIVNAAPVIFEKKKVPLRGKPTPVLLLRNVVLAGEVVDTLEDDVAEHCEKFGDVVRVFIFEIEEEGFAKEETVRIFVEFVDTKTAISAGAELDGRVFANRVVKASYYDVERFEAGDLGPQAGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBC4</accession>
    <name>A4SBC4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422752.1">
        <property type="nucleotide sequence ID" value="XM_001422715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBC4"/>
    <dbReference type="GeneID" id="5006809"/>
    <dbReference type="Gramene" id="ABP01069">
        <property type="protein sequence ID" value="ABP01069"/>
        <property type="gene ID" value="OSTLU_25883"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25883"/>
    <dbReference type="eggNOG" id="ENOG502R8WZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_886793_0_0_1"/>
    <dbReference type="OMA" id="HEAMHMV"/>
    <dbReference type="OrthoDB" id="498696at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP01069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="314" mass="34505" checksum="B399E6EAFF3D4950" modified="2007-05-15" version="1">MGRFRGVDAPEIDLDAYVASLTPSRARHASHARASASRDAVRVARWLENEKVLLLTFRDAATQRRALGRLSMFIEDPEWRGKIADALPSGARGGVANYSGHNARAREVCAFYAAARREGGCWEDEEAVVEALVRCGALRRNEDGAVEVSESAMGRGGWCEYDGEDDDEESVVPETCVIAVCASGDAREVQDALLHEAMHGLWYARENYASWCYEFYRGDALGDEERAIWVDFLRELRYDVSVREVVVNEFQAYMATERVLFGGDGATANKGKKSGGAIVRAGDALAAMQKKFAAAARDAVPDPPRCGQLTVVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQT1</accession>
    <name>A4RQT1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">MPT family transporter: inner membrane translocase (Import) Tim17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_7704</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415788.1">
        <property type="nucleotide sequence ID" value="XM_001415751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQT1"/>
    <dbReference type="STRING" id="436017.A4RQT1"/>
    <dbReference type="GeneID" id="4999642"/>
    <dbReference type="Gramene" id="ABO94080">
        <property type="protein sequence ID" value="ABO94080"/>
        <property type="gene ID" value="OSTLU_7704"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7704"/>
    <dbReference type="eggNOG" id="KOG1652">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087811_3_1_1"/>
    <dbReference type="OMA" id="FDCTFQY"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="136" mass="13973" checksum="56811E3391C24E38" modified="2007-05-15" version="1" fragment="single">MASVDHGREPCPHRIFDDVGGAFAMGAVGGGVVNLVKGAYNAPRGFALASAAEAIRREAPRIGGSFAVWGGLFSAFDCALVAARRKEDPWNPIISGAATGGALQLRYGLPSAARSAAFGGFLLAVIEGISIMLTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQY3</accession>
    <name>A4RQY3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_28825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SHOC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415811.1">
        <property type="nucleotide sequence ID" value="XM_001415774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQY3"/>
    <dbReference type="STRING" id="436017.A4RQY3"/>
    <dbReference type="GeneID" id="4999682"/>
    <dbReference type="Gramene" id="ABO94103">
        <property type="protein sequence ID" value="ABO94103"/>
        <property type="gene ID" value="OSTLU_28825"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28825"/>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035565_0_0_1"/>
    <dbReference type="OMA" id="MVGFKAN"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF54">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="249"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="484" mass="52319" checksum="F3BDACD24A232298" modified="2007-05-15" version="1">MGAGTSTKDGGVDIDVVAPKRVVSYARASGDAATKCERVLEDLRAGALDDATELDVSNCGLTELPDAVGRLTRLEFLNAGGNALRTLPESIENCRKLKRAFFLGNAFERVPEVLGRLPELFMVSFKACAVREVSEDALAPSLGWLILSDNQIERLPASLGRCAPMRKLMLAGNKLRALPESMRELKNLELLRLADNRFETFPSWILESPRLSWFAAAANPATDTIGDKAKTRANSADVVTVDWSELGVAEDAEPLGKGASGAVYAGRWNGETVAVKVYNNAAKTSDGRPEDEMTASVLAATIKSEGTIKTIARFQRGDSRGLVMQYLDHASWKDLGKPPSFDTVARDTYDDDVRFTAKEIMAVARDVGSALRELHAMGVVHGDVYAHNILHVKESPGIEPRAKLGDFGAAWFYERDSSNARTIELNEARAFGAVLEEVCARHDGVDGVHPIAALAALAAGLLGERGSRLLFDDIVQRIAAIQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR43</accession>
    <name>A4RR43_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_28884</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptotagmin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415834.1">
        <property type="nucleotide sequence ID" value="XM_001415797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR43"/>
    <dbReference type="STRING" id="436017.A4RR43"/>
    <dbReference type="GeneID" id="5000038"/>
    <dbReference type="Gramene" id="ABO94126">
        <property type="protein sequence ID" value="ABO94126"/>
        <property type="gene ID" value="OSTLU_28884"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28884"/>
    <dbReference type="eggNOG" id="KOG1012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_315093_0_0_1"/>
    <dbReference type="OMA" id="KTHIGAD"/>
    <dbReference type="OrthoDB" id="566659at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd21677">
        <property type="entry name" value="SMP_SYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045050">
        <property type="entry name" value="Synaptotagmin_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039010">
        <property type="entry name" value="Synaptotagmin_SMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10774:SF190">
        <property type="entry name" value="C2 CALCIUM_LIPID-BINDING ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10774">
        <property type="entry name" value="EXTENDED SYNAPTOTAGMIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17047">
        <property type="entry name" value="SMP_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="15">
        <location>
            <begin position="417"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="610"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="758"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO94126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="928" mass="104259" checksum="6EC2BAFBB548A98F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR52</accession>
    <name>A4RR52_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR52"/>
    <dbReference type="GeneID" id="4999595"/>
    <dbReference type="Gramene" id="ABO94129">
        <property type="protein sequence ID" value="ABO94129"/>
        <property type="gene ID" value="OSTLU_28893"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28893"/>
    <dbReference type="HOGENOM" id="CLU_3035767_0_0_1"/>
    <dbReference type="OrthoDB" id="689350at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="55" mass="5819" checksum="E1AD3C84C7DEC498" modified="2007-05-15" version="1">MNNDKGVKVTAVDVDLATKIVRVSIDCESVVDGVTKLPALVETVVEGGFEAEPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR75</accession>
    <name>A4RR75_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4352 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_10572</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415850.1">
        <property type="nucleotide sequence ID" value="XM_001415813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR75"/>
    <dbReference type="STRING" id="436017.A4RR75"/>
    <dbReference type="GeneID" id="5000004"/>
    <dbReference type="Gramene" id="ABO94142">
        <property type="protein sequence ID" value="ABO94142"/>
        <property type="gene ID" value="OSTLU_10572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10572"/>
    <dbReference type="HOGENOM" id="CLU_2489996_0_0_1"/>
    <dbReference type="OrthoDB" id="497228at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9145" checksum="3BD2359D9F6E6663" modified="2007-05-15" version="1" fragment="single">GGVPGSGTYKAKCILLSFKALNPTKDVVYNADVFGSVKDQANDDVLNSGRIGSIKELQPGENDARLELTVGASQPLPLKLKAFKGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRC7</accession>
    <name>A4RRC7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_23908</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415876.1">
        <property type="nucleotide sequence ID" value="XM_001415839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRC7"/>
    <dbReference type="STRING" id="436017.A4RRC7"/>
    <dbReference type="GeneID" id="4999567"/>
    <dbReference type="Gramene" id="ABO94168">
        <property type="protein sequence ID" value="ABO94168"/>
        <property type="gene ID" value="OSTLU_23908"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_23908"/>
    <dbReference type="eggNOG" id="KOG1278">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010714_4_1_1"/>
    <dbReference type="OMA" id="KVYYMFG"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF111">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007360213" description="Transmembrane 9 superfamily member" evidence="9">
        <location>
            <begin position="30"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="498"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="600"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="639" mass="73473" checksum="B87AD479BBB274F4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRH4</accession>
    <name>A4RRH4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MC family transporter: uncoupling protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_29018</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415902.1">
        <property type="nucleotide sequence ID" value="XM_001415865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRH4"/>
    <dbReference type="GeneID" id="4999387"/>
    <dbReference type="Gramene" id="ABO94194">
        <property type="protein sequence ID" value="ABO94194"/>
        <property type="gene ID" value="OSTLU_29018"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29018"/>
    <dbReference type="eggNOG" id="KOG0753">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_14_2_1"/>
    <dbReference type="OMA" id="LIPCWLR"/>
    <dbReference type="OrthoDB" id="6703404at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="85"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="181"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="277" mass="29270" checksum="2E64FB13F02D39ED" modified="2007-05-15" version="1">MCATTVTNPLDVIKVRMQTSARRRAGALVGTALDVGRREGLGTFWRGISPALTRAALYGGCRLGLYDPMLRVVAPAVEREREGAPRVATRLLAGAASGAFAAAALNPTELLKTRMQTEAGASTTLVGHLRAVVREGGVGGLWRGSGLAMMRSAVLTATQVATYGEVKRRVVDLGLVDADGAKWRLHFAVAMLTGVVTTATTNPVDMLKTRLYVANAAASGGANAPTVRGTLVDVLARYGPFGLFRGFSANYMRLGPQTVVTFVVAEYLRERFGMSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRL7</accession>
    <name>A4RRL7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415591.1">
        <property type="nucleotide sequence ID" value="XM_001415554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRL7"/>
    <dbReference type="GeneID" id="4999530"/>
    <dbReference type="Gramene" id="ABO93883">
        <property type="protein sequence ID" value="ABO93883"/>
        <property type="gene ID" value="OSTLU_29061"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29061"/>
    <dbReference type="HOGENOM" id="CLU_138791_0_0_1"/>
    <dbReference type="OMA" id="RAMAKPK"/>
    <dbReference type="OrthoDB" id="10503171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="13496" checksum="92E214BDF0CDB0A3" modified="2007-05-15" version="1">MAAPKVPVVNSRAHQNMTMETDDANDARRSRDVVVDAETLARAEDAARRNDEAVAWGMNAVGKADIFLKTKKGSGVTKKGRRPDGAPTPRQLAAQTFQNDSKARKKMKRQLKQVKSARLKVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRS8</accession>
    <name>A4RRS8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_29124</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415623.1">
        <property type="nucleotide sequence ID" value="XM_001415586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRS8"/>
    <dbReference type="STRING" id="436017.A4RRS8"/>
    <dbReference type="GeneID" id="4999871"/>
    <dbReference type="Gramene" id="ABO93915">
        <property type="protein sequence ID" value="ABO93915"/>
        <property type="gene ID" value="OSTLU_29124"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29124"/>
    <dbReference type="eggNOG" id="KOG0346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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        <property type="entry name" value="HELICASE_CTER"/>
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    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="17"/>
            <end position="198"/>
        </location>
    </feature>
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        <location>
            <begin position="244"/>
            <end position="430"/>
        </location>
    </feature>
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            <begin position="202"/>
            <end position="222"/>
        </location>
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        <location>
            <begin position="316"/>
            <end position="345"/>
        </location>
    </feature>
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        <location>
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            <end position="526"/>
        </location>
    </feature>
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        <location>
            <begin position="542"/>
            <end position="583"/>
        </location>
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        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
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        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
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        <location>
            <begin position="565"/>
            <end position="583"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00006517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00038041"/>
        </source>
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            <dbReference type="ARBA" id="ARBA00047984"/>
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        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
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            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO93915.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="583" mass="63369" checksum="8D98F91E6D2CF127" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRX6</accession>
    <name>A4RRX6_OSTLU</name>
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        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="9" type="ORF">OSTLU_6737</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415943.1"/>
    </dbReference>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
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    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
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        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="S_TKc"/>
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    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="205" mass="22631" checksum="B26E95E07B0234A9" modified="2007-05-15" version="1" fragment="single">VGDLIGRGIYGSVRRAVDRKTGDILAVKSILRTKVDENAIKDECDALQVLCGHHPNFPLKLMVYEDSPLLKSEVTHIVTDIYTGGTLIQAIAQRGLFDEGDWCVFANQLLGAVSFMHSLGVAHRDLKPDNIMLKEPWSPKPGAIPTLKIIDFGSATFCLAHETMKGHVGTKFFSAPEVLRRKPYTKKCDVWSVGVLLMVLLKGYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS80</accession>
    <name>A4RS80_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415697.1">
        <property type="nucleotide sequence ID" value="XM_001415660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS80"/>
    <dbReference type="GeneID" id="4999636"/>
    <dbReference type="KEGG" id="olu:OSTLU_92243"/>
    <dbReference type="HOGENOM" id="CLU_1899690_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="134" mass="14885" checksum="5CE92DD7C397D118" modified="2007-05-15" version="1" fragment="single">LDVSGVRAPSRTRRRDRIARELEIRLLDTLAVRPRRGLLVVRARAPRGVAPGPSVGGRRNRARNLSLARVTGVEDGLRRVKVARVDGYFPRAGFDAHERASSAREGRNSLERGRLARERGSTRPSERSFVVVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSU9</accession>
    <name>A4RSU9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ddx49-related DEAD box helicase superfamily II protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Ddx49</name>
        <name evidence="10" type="ORF">OSTLU_119572</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416184.1">
        <property type="nucleotide sequence ID" value="XM_001416147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSU9"/>
    <dbReference type="STRING" id="436017.A4RSU9"/>
    <dbReference type="GeneID" id="5000121"/>
    <dbReference type="Gramene" id="ABO94477">
        <property type="protein sequence ID" value="ABO94477"/>
        <property type="gene ID" value="OSTLU_119572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119572"/>
    <dbReference type="eggNOG" id="KOG0340">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_1_1"/>
    <dbReference type="OMA" id="IWKNSIQ"/>
    <dbReference type="OrthoDB" id="10261904at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17955">
        <property type="entry name" value="DEADc_DDX49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="9">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="33"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="233"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="46350" checksum="28C38CC9385FE114" modified="2007-05-15" version="1">MTSFDKLGLSGVLLRNIRQLGFTEPSSVQKSCIPPILQGRDVIGIANTGSGKTAAFALPVVHVLSVDPHGVFALCLSPTRELAYQIAEQFAVFSVGMSLRCEVVIGGEDLLRQASSLSKRPHIVVATPGRLLEHFMHSSDTIECFQRLKFLILDEADRLLDSSFEAELRYLLTNLPQKRQTLMFSATITPSVIALKPLLGQRAFYYEEKGELTTPTGCAQYYCFMPEKVKDTYLVHVLRELVSSKSTRAMIFCPTVQKCEMVSHMLHNLGIAACSLHAAKKQRDRHSTLNAFKSTMVKILVATDVAARGLDLPDVELVVNYDIPSDPRQYIHRIGRTARFHATGQAISLVTQYDVGKIKKIEKHLGHELEEFHVQEADVNKLVGEVFASRKMAKLHMASPGGFDEQLSAKKKRQSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTS5</accession>
    <name>A4RTS5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416548.1">
        <property type="nucleotide sequence ID" value="XM_001416511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTS5"/>
    <dbReference type="STRING" id="436017.A4RTS5"/>
    <dbReference type="GeneID" id="5001059"/>
    <dbReference type="Gramene" id="ABO94841">
        <property type="protein sequence ID" value="ABO94841"/>
        <property type="gene ID" value="OSTLU_30367"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30367"/>
    <dbReference type="eggNOG" id="ENOG502S0BW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_410700_0_0_1"/>
    <dbReference type="OMA" id="LECWRVP"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="65532" checksum="2FAC3A5710C64C0B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTV4</accession>
    <name>A4RTV4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nop domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_30396</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for 60S ribosomal subunit biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416562.1">
        <property type="nucleotide sequence ID" value="XM_001416525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTV4"/>
    <dbReference type="STRING" id="436017.A4RTV4"/>
    <dbReference type="GeneID" id="5000802"/>
    <dbReference type="Gramene" id="ABO94855">
        <property type="protein sequence ID" value="ABO94855"/>
        <property type="gene ID" value="OSTLU_30396"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30396"/>
    <dbReference type="eggNOG" id="KOG2572">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015495_5_2_1"/>
    <dbReference type="OMA" id="MGMRSNW"/>
    <dbReference type="OrthoDB" id="6780543at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000004">
        <property type="entry name" value="Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000001">
        <property type="entry name" value="Probable Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="7">
        <location>
            <begin position="280"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="410"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00058481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="474" mass="51793" checksum="924C596E1D251284" modified="2007-05-15" version="1">MLLLFETPAGYSLFKVKAEKKLQDAEKLQDAFSTVEGAKKMVSMKAFSKFENTTEALAAAATLVDSKVGKNLKKFLSKHAEGETLAVADSKLGAAIKEKLGINCVADSGVMELMRGVRYQLNELIGGLTDADLAPMALGLSHSLSRYKLKFSPDKVDTMVIQAIGLLDELDKELNTYSMRVREWYGWHFPELTKIIADNMQYAKAAKLMGDRAKAAGIDFSGILDEDVEQEVKDAAIISMGTEISEEDLSNIGQLADQVISLSEYRAQLYDYLKARMNAIAPNLTVLVGELVGARLISHAGSLMNLAKHPASTVQILGAEKALFRALKTKHETPKYGLIYHASLIGQAAPKFKGKISRVLAAKCALSIRVDALGESSEATIGVEAREKVEARLRQLEGKTLGEASGVKKMSGDIKKHDKDRNADAPALLTAPRSYNPDKDATKKEKKEKKDKKEKRKSEGDSPKSSKKSKKNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTV6</accession>
    <name>A4RTV6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_49010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416563.1">
        <property type="nucleotide sequence ID" value="XM_001416526.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RTV6"/>
    <dbReference type="GeneID" id="5000845"/>
    <dbReference type="Gramene" id="ABO94856">
        <property type="protein sequence ID" value="ABO94856"/>
        <property type="gene ID" value="OSTLU_49010"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49010"/>
    <dbReference type="eggNOG" id="KOG0915">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000880_2_1_1"/>
    <dbReference type="OMA" id="CRIKDIE"/>
    <dbReference type="OrthoDB" id="16066at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024372">
        <property type="entry name" value="Ecm29_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055443">
        <property type="entry name" value="HEAT_ECM29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF19">
        <property type="entry name" value="PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13001">
        <property type="entry name" value="ECM29_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24492">
        <property type="entry name" value="HEAT_ECM29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome component Ecm29 N-terminal" evidence="6">
        <location>
            <begin position="11"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome adapter and scaffold protein ECM29 HEAT-repeat" evidence="7">
        <location>
            <begin position="1287"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1843" mass="200210" checksum="07E9CAD678FDAE48" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUG8</accession>
    <name>A4RUG8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Valine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="4">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_33832</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416669.1">
        <property type="nucleotide sequence ID" value="XM_001416632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUG8"/>
    <dbReference type="STRING" id="436017.A4RUG8"/>
    <dbReference type="GeneID" id="5000870"/>
    <dbReference type="Gramene" id="ABO94962">
        <property type="protein sequence ID" value="ABO94962"/>
        <property type="gene ID" value="OSTLU_33832"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33832"/>
    <dbReference type="eggNOG" id="KOG0432">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_0_1_1"/>
    <dbReference type="OMA" id="LDTWMDS"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <sequence length="1056" mass="118580" checksum="0F41E44E66119697" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUG9</accession>
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        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">OSTLU_24233</name>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
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                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="28"/>
        </location>
    </feature>
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        </location>
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        </location>
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        </location>
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        </location>
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            <end position="78"/>
        </location>
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        </location>
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        <location>
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        </location>
    </feature>
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            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUN6</accession>
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        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">OSTLU_34148</name>
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        </lineage>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
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                <person name="Jancek S."/>
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                <person name="Bowler C."/>
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                <person name="Robbens S."/>
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            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
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        <subcellularLocation>
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            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
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    <dbReference type="HOGENOM" id="CLU_567863_0_0_1"/>
    <dbReference type="OMA" id="CNNIGLR"/>
    <dbReference type="OrthoDB" id="496660at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="466" mass="50328" checksum="C3A3A402FA7478F0" modified="2007-05-15" version="1">MGKLTTKDVRAYARAIGTRLRKITCDLGHKILYDPIRRDPTAKYVDVYDDNVQDLVETLAIPQLHVRRLKLHSSDPGSVRAAAVAAASNGPNKVESFDASWSLRISNEGARAVAEVLAQGWDLKRLALRKVNISDDGAVSLAEAIKASAESGTSKLRWLDLGSNDVRSRGAVAIGEALEHPGVNITRLTLRGNGICSEGMDALGKGISMSSTLRRIDLAHNGFGDRGAIAFADALSRGTAPNLRVLLLGFNSIGPDGMRALMQALMHTDVEHLDVGCNVIGASGAKAIAEMINSTRLKSLNLACNNIGLRGERSGLTALAKALEKNKTLEILNLRGNALHTNCAQDIADVLLEETALIQLNVGYNELYDNGAWEIAEALEENTTLLGLDFQRNEVTDAGASNIAKTLAVNSIIQEIDLRSNMISSEGVAKLQPYGLKTNTRWQLEPPKYKEKPKPRFSARKPKANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUU9</accession>
    <name>A4RUU9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_34480</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 21">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the 7-subunit TFIIH core complex composed of XPB, XPD, TFB1/GTF2H1, GTF2H2/P44, TFB4/GTF2H3, TFB2/GTF2H4 and TFB5/GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CYCH1/cyclin H1, CDKD and MAT1/At4g30820 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416734.1">
        <property type="nucleotide sequence ID" value="XM_001416697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUU9"/>
    <dbReference type="STRING" id="436017.A4RUU9"/>
    <dbReference type="GeneID" id="5001140"/>
    <dbReference type="Gramene" id="ABO95027">
        <property type="protein sequence ID" value="ABO95027"/>
        <property type="gene ID" value="OSTLU_34480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34480"/>
    <dbReference type="eggNOG" id="KOG1123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008213_0_0_1"/>
    <dbReference type="OMA" id="RCQEIDY"/>
    <dbReference type="OrthoDB" id="10262986at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="286"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="505"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="746"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00065951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO95027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="781" mass="87598" checksum="7A34411A6EE0E9A0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV49</accession>
    <name>A4RV49_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_24310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">CCE9901</strain>
        </source>
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        <property type="protein sequence ID" value="ABO95370"/>
        <property type="gene ID" value="OSTLU_24310"/>
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        <property type="component" value="Chromosome 3"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO95370.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="405" mass="43773" checksum="297F1642DA2E382B" modified="2007-05-15" version="1">MASTDTKAMKETPLSVLSRTNLAKYLTERHALAGKTCGDQPESLRGKCTLVLSSDSSFQEALSSMNRFRVSSMPLVRYKSGASRDVGAYDALCFLSNGDLVTTLIEACDKAELNARDDDVLGLMGRMATIGLEIESLPLKQARTKWDGTVIWKSATATQSLAECLERCLYISPSEKPGDVRLRALPHRFAVMNSDNAIEHIVSQSDIVMYLHTNRDILTPLFTEATVNELGLASTPGIAFVGASTPTIEAFREMERHRVGAVPIVDEATRTLIGTLSESDLTHLRGGASFAALALPVAEFLLHAHKLSVSTPAQQSGGLYNPNTSAFAAALMRHRERLVVSCRPSDTLTDVLTKMDVNAVHRVWVVDDAGVPTGVIALADVLAVIAQMGMSTEEVAKQRDKMVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVD5</accession>
    <name>A4RVD5_OSTLU</name>
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        <recommendedName>
            <fullName evidence="1">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30936</name>
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    <organism evidence="2 3">
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="58"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="187" mass="20266" checksum="F0AD8A4DE153EBB2" modified="2007-05-15" version="1">MYTANATQVSCTRANATRALRRSGTSTTRRASTVTRAFTEHNEGDMLAKYPLDADTYKVELDCSQSNIQLGLLLEAGPDDRPRVKTIRPGGNAKGKVNVGDVVLATTYTVLKGVRDESWGSSMRGWLDTAETTSAQAEAAMTTNSSSVGLIMSRNYKATGLKRANVDEDTRSWAARVAAEARAKREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVJ8</accession>
    <name>A4RVJ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417116.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RVJ8"/>
    <dbReference type="GeneID" id="5001155"/>
    <dbReference type="Gramene" id="ABO95446">
        <property type="protein sequence ID" value="ABO95446"/>
        <property type="gene ID" value="OSTLU_31000"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31000"/>
    <dbReference type="HOGENOM" id="CLU_251305_0_0_1"/>
    <dbReference type="OrthoDB" id="10573912at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
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            <end position="138"/>
        </location>
    </feature>
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        <location>
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            <end position="847"/>
        </location>
    </feature>
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            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="596"/>
        </location>
    </feature>
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        <location>
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            <end position="739"/>
        </location>
    </feature>
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            <begin position="763"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95446.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1451" mass="153088" checksum="07996567BC184411" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW37</accession>
    <name>A4RW37_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_1854</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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            <taxon>Ostreococcus</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; L-ascorbate biosynthesis.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO95548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW37"/>
    <dbReference type="STRING" id="436017.A4RW37"/>
    <dbReference type="GeneID" id="5001434"/>
    <dbReference type="Gramene" id="ABO95548">
        <property type="protein sequence ID" value="ABO95548"/>
        <property type="gene ID" value="OSTLU_1854"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1854"/>
    <dbReference type="eggNOG" id="KOG4730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021072_0_0_1"/>
    <dbReference type="OMA" id="KQWANEW"/>
    <dbReference type="OrthoDB" id="610608at2759"/>
    <dbReference type="UniPathway" id="UPA00132"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016633">
        <property type="term" value="F:galactonolactone dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080049">
        <property type="term" value="F:L-gulono-1,4-lactone dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019853">
        <property type="term" value="P:L-ascorbic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010029">
        <property type="entry name" value="GL_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01676">
        <property type="entry name" value="GLDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="483" mass="54159" checksum="57D73EA3FDA953AC" modified="2007-05-15" version="1" fragment="single">TVENWSGTKRVECEKVLTPESAEALERAVRSGKHRKLRPCGSALSPNGVAFEERGMLSMALLDEVLEVDAEKKLLRVQAGARVREVVEALRPHGLTLQNYASIREQQMGGFTQVGAHGTGARIPPVDETVVEMKLVTPARGTLTLSATSEPELFKLAKCGIGALGAVTELTIKCVDAHKLVENTWTATPGEIEKNHEKWLREYQHIRYMWIPHTETVVVVASNPLKPGEREPWIRSGMSEKKRVEPLVRLLKEVAPDVNPENMGFGQLRDELLKVNPLDFEHVKRVNAAEAEFWKRSTGTRVDWSDQILGFDCGGQQHVLEVAFPAGELESTPPASDAPLRADLRFMRDLRRLIVENQIPAHAPIEQRWTSGSSSPMSPSAGSPNSLHSWVGIIMYLPTTVEAEREAITNAFTEYGYKEFDALGDKYELRTHWAKIEVPEDIRRLDKTRTKLREHYPVKEFNAARKYLDPYGVFTNGIIASLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW62</accession>
    <name>A4RW62_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_6446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417529.1">
        <property type="nucleotide sequence ID" value="XM_001417492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW62"/>
    <dbReference type="STRING" id="436017.A4RW62"/>
    <dbReference type="GeneID" id="5001338"/>
    <dbReference type="Gramene" id="ABO95822">
        <property type="protein sequence ID" value="ABO95822"/>
        <property type="gene ID" value="OSTLU_6446"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6446"/>
    <dbReference type="eggNOG" id="ENOG502QQ38">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082531_0_0_1"/>
    <dbReference type="OMA" id="SWWVTVP"/>
    <dbReference type="OrthoDB" id="2019412at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018710">
        <property type="entry name" value="DUF2232"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37185">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37185:SF3">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09991">
        <property type="entry name" value="DUF2232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="180" mass="19699" checksum="2D21FAA682A9A428" modified="2007-05-15" version="1" fragment="single">RVLVEAAMLAAMTGLAFHISSLFRFDAYFGALFPLPVVIACARSGRAAAMRTLVVASLLLLMISGPLRALNYFFLHGVLAYVLSSLWSSGSSWWVTVPASALTRTFGILASLSISSLLYRENVMKLLVTQMYSLLDQFAANVGATFAPTIGWVWATALFFILVNSFSYTLILHMVYTIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWC3</accession>
    <name>A4RWC3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FBP16-7</name>
        <name evidence="9" type="ORF">OSTLU_31289</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417556.1">
        <property type="nucleotide sequence ID" value="XM_001417519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWC3"/>
    <dbReference type="GeneID" id="5001518"/>
    <dbReference type="Gramene" id="ABO95849">
        <property type="protein sequence ID" value="ABO95849"/>
        <property type="gene ID" value="OSTLU_31289"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31289"/>
    <dbReference type="eggNOG" id="ENOG502S5DS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1443271_0_0_1"/>
    <dbReference type="OMA" id="ANHEEIA"/>
    <dbReference type="OrthoDB" id="2014544at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47861">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47861:SF3">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0697">Rotamase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="188" mass="19863" checksum="B8063FA633CB854A" modified="2007-05-15" version="1">MPDVDFIGTILQDVRKGQKGFATRMSVHEDARADASEGFPVTGDIVKIQFGVETGEGEVLQDAAATEAVTFEVGASDVMGNPLFKAFDEAVRKLNVGNSAVVSASGGDYDPNLLFSVPANHEEIARLRAEWSDKGGLVEGLTVTLVNGQPAVVRAMDAEKVVLDANHPFAGADVFFKVTLLGVNVDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWG5</accession>
    <name>A4RWG5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_92648</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417573.1">
        <property type="nucleotide sequence ID" value="XM_001417536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWG5"/>
    <dbReference type="GeneID" id="5001465"/>
    <dbReference type="Gramene" id="ABO95866">
        <property type="protein sequence ID" value="ABO95866"/>
        <property type="gene ID" value="OSTLU_92648"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92648"/>
    <dbReference type="HOGENOM" id="CLU_1410551_0_0_1"/>
    <dbReference type="OMA" id="YETHVAS"/>
    <dbReference type="OrthoDB" id="10578476at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="5">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="21400" checksum="2A05EBCE24FD1894" modified="2007-05-15" version="1">MPAPGPKDGHASKASRDLGGRRGLTREIKNVSVKSNGFKGGGQGGVATTNRGLAGVRLGEGGSARSVAARQRLRARFLAGEAGKAAKAARTVGRKRAREAAATATTTTTTTTTAATATTTTTTTTTAAAADARAVEGDVVEAKSDDAHVAGSENDYFCDVCACKCGSRNNYETHVASKRHRQNRDAARGREILASLKRQRVEISGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWK3</accession>
    <name>A4RWK3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FBP14-1</name>
        <name evidence="3" type="ORF">OSTLU_31366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417346.1">
        <property type="nucleotide sequence ID" value="XM_001417309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWK3"/>
    <dbReference type="STRING" id="436017.A4RWK3"/>
    <dbReference type="GeneID" id="5001566"/>
    <dbReference type="Gramene" id="ABO95639">
        <property type="protein sequence ID" value="ABO95639"/>
        <property type="gene ID" value="OSTLU_31366"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31366"/>
    <dbReference type="eggNOG" id="KOG0549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_10_2_1"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044183">
        <property type="entry name" value="PNSL4/FKBP13-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47833:SF2">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47833">
        <property type="entry name" value="PHOTOSYNTHETIC NDH SUBUNIT OF LUMENAL LOCATION 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="2">
        <location>
            <begin position="70"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="168" mass="16851" checksum="58B77BE191FA4AA9" modified="2007-05-15" version="1">MPPTPSGGGRMTLAGVATAPRALADTRRATMAKTIVGALAPLVAARARASDGVVIVEETVGRGVEVLAGVDVVKVNYTVALASSKARVDSAKFFVFGVGAGEVVEGFDAIVGGDGATPPMRVGGARRAVVPAALAYGDRGAGCDKTGNACSIPPGEDLEFTVELLEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWT7</accession>
    <name>A4RWT7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_15241</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417633.1">
        <property type="nucleotide sequence ID" value="XM_001417596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWT7"/>
    <dbReference type="GeneID" id="5001455"/>
    <dbReference type="Gramene" id="ABO95926">
        <property type="protein sequence ID" value="ABO95926"/>
        <property type="gene ID" value="OSTLU_15241"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15241"/>
    <dbReference type="eggNOG" id="ENOG502QVWK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037177_0_0_1"/>
    <dbReference type="OMA" id="GQNACKF"/>
    <dbReference type="OrthoDB" id="568028at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF3">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="355" mass="38636" checksum="109A6CDEF2198167" modified="2007-05-15" version="1" fragment="single">MRAAAADDGASAVDVIVRGRIIGRRRVSKRLAFYDVRVDDALDAAAVGADDATLRDDGRRARAHAALSAGELIEMVVKASHGAFVTHEDVAWAQKTSLKLGNTGAFRGTLSRRAANAHGEWSLACEEVVEIVEEWAKVNPGKAFQRELYLPNEGGESGIGGEASSRVADGASVGACKFFINNAFCAKGDKCKYAHDRAVQREWIAARKANRREIAAKECGDPHGDSVASKQMRAQRFAQFLLEKFGAEVLNAGTGVLDVAGGRGDVSFELHTKLGIKSTLVEPRERKLNKKQHKWLKKKLKTDESTAPEAESMLCEQIRTEFSSENFAQFKDCSAIIGMHPDQATEAIVDFALQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWY0</accession>
    <name>A4RWY0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417656.1">
        <property type="nucleotide sequence ID" value="XM_001417619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWY0"/>
    <dbReference type="GeneID" id="5002095"/>
    <dbReference type="Gramene" id="ABO95949">
        <property type="protein sequence ID" value="ABO95949"/>
        <property type="gene ID" value="OSTLU_31496"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31496"/>
    <dbReference type="HOGENOM" id="CLU_2175248_0_0_1"/>
    <dbReference type="OMA" id="EDPCTDN"/>
    <dbReference type="OrthoDB" id="496606at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="110" mass="12259" checksum="42F11000C29D3071" modified="2007-05-15" version="1">MQIVDSTTSEYMRRRDEAASFKCSGGMFDCDSDRREYARAQTERLRARIATRDPEMDAEEVSPCTVEDPCTDNVLQAALAGVQGLTTSEKLEKMGRPTDAVNSSSQYFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX07</accession>
    <name>A4RX07_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR-repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TPR2</name>
        <name evidence="3" type="ORF">OSTLU_87186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417913.1">
        <property type="nucleotide sequence ID" value="XM_001417876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX07"/>
    <dbReference type="STRING" id="436017.A4RX07"/>
    <dbReference type="GeneID" id="5001672"/>
    <dbReference type="Gramene" id="ABO96206">
        <property type="protein sequence ID" value="ABO96206"/>
        <property type="gene ID" value="OSTLU_87186"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87186"/>
    <dbReference type="eggNOG" id="KOG1124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031917_0_0_1"/>
    <dbReference type="OMA" id="IHIGIHG"/>
    <dbReference type="OrthoDB" id="541719at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008428">
        <property type="term" value="F:ribonuclease inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009657">
        <property type="term" value="P:plastid organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010114">
        <property type="term" value="P:response to red light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044624">
        <property type="entry name" value="Mbb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917:SF1">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="200"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="341"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="544" mass="60771" checksum="1DE67761C6470F49" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX40</accession>
    <name>A4RX40_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417691.1">
        <property type="nucleotide sequence ID" value="XM_001417654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX40"/>
    <dbReference type="GeneID" id="5001976"/>
    <dbReference type="Gramene" id="ABO95984">
        <property type="protein sequence ID" value="ABO95984"/>
        <property type="gene ID" value="OSTLU_92711"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92711"/>
    <dbReference type="eggNOG" id="ENOG502RZ80">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065902_2_1_1"/>
    <dbReference type="OMA" id="YPKETIA"/>
    <dbReference type="OrthoDB" id="497927at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098:SF2">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="2">
        <location>
            <begin position="196"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="360" mass="38682" checksum="E19F436B2F524595" modified="2007-05-15" version="1">MRAAATARPSTARPSTSARRARRARTRAVRDERIDFLSTTLIVDDLVFADGTTRMAVLGGGGPQTLFGAAVTSDGELTLGLVAGVGEGDCPETCARWLADIGAEAFLLTLGTSTPRAWQITERDGRRTQVWRLDASDALYAMLRPKYAIWPEKCKRANAVHFGLNPSRPDVELVQALREGGCGLISIEPFTHAEAPLSRKDLENLVSMGDVFSPNEREARSFFAKGDGMSPKDLIKAMRKAGATICCLRRGSRGAMVYDSRTNEGYECEALSANVVDETGCGNAFCGAFAAALAQGATIRDGLIRGTVAASIMLEHVGVPNGTLVEYRAEAARRANLINPVAFSLDEEVAAFVDFDEYIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXA2</accession>
    <name>A4RXA2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417962.1">
        <property type="nucleotide sequence ID" value="XM_001417925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXA2"/>
    <dbReference type="GeneID" id="5001701"/>
    <dbReference type="Gramene" id="ABO96255">
        <property type="protein sequence ID" value="ABO96255"/>
        <property type="gene ID" value="OSTLU_31624"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31624"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_790726_0_0_1"/>
    <dbReference type="OMA" id="FANLMEH"/>
    <dbReference type="OrthoDB" id="498272at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="227"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="381" mass="43182" checksum="082B5AEF77FA2D9D" modified="2007-05-15" version="1">MPAAREDAASEYPVIDVGPLLSAGDPNEDVRFILARRREVGRALLAACERFGFFSIVCTIQKESIPWADVVDLLTLNTRDDLPDDFLWEYARHDRSEGCLIEGKDLTFAHVDAWFSQKQADKDAYAMTNGRGYQRIGENVTNGRRDQHEAIDFYRPCAVSDGGLRAPHPYIGPNDLNERVDRYAKGMTRIGKYILRALLGAIRKEYLHYRIADDFTEDILEDDIAGCPFWILRLINSPGCDSDGEKTSCGWHTDYGLLTFIHATHPGLQIEVSGKIIDVPHHPEHMVCNVGEMLQLFTDDSLKATRHRVVRKPSDENCARPRISIAFFYEPNYDAVISNRHLTDQSALESGYSSPREVRYADFLRQKVATNFAKVDEDPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY17</accession>
    <name>A4RY17_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417851.1">
        <property type="nucleotide sequence ID" value="XM_001417814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY17"/>
    <dbReference type="GeneID" id="5002084"/>
    <dbReference type="Gramene" id="ABO96144">
        <property type="protein sequence ID" value="ABO96144"/>
        <property type="gene ID" value="OSTLU_31892"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31892"/>
    <dbReference type="HOGENOM" id="CLU_1941614_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="130" mass="14112" checksum="5E25686B998289E5" modified="2007-05-15" version="1">MKAKAPQAQGMRWMKRCKRRAKERARARAEWGEANGADARAETTTTETTETTETETTTTTTTSALDRALQSGKKKNKGKAKKKESYAVRAASTVRAGVSKKRDGAKTSEATAPKYASGNPFAALAMARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY51</accession>
    <name>A4RY51_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417869.1">
        <property type="nucleotide sequence ID" value="XM_001417832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY51"/>
    <dbReference type="GeneID" id="5001882"/>
    <dbReference type="Gramene" id="ABO96162">
        <property type="protein sequence ID" value="ABO96162"/>
        <property type="gene ID" value="OSTLU_15585"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15585"/>
    <dbReference type="HOGENOM" id="CLU_984809_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATA-type" evidence="2">
        <location>
            <begin position="198"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="283" mass="30751" checksum="53CE7EBAA9D3F53E" modified="2007-05-15" version="1">MIVSRRARADDGGRAARDASARDGGSSATGILSGAEIATLSEHSYDRLLRLKPREIGRGDRLTAEETAVTFDTFGPASVSVDIVSVERDEGGTGEGRGRGTADAFEFFEKRAFLKESSKRNAMDLARLRRTRIADERAKVRERERERAASARPPGGPGANGAPPEVRRKKRGRGRPRKDAVNAASRQRDARGRKRMYDRSTETCAECGTHQTPQWRSLSAQFAVLERAGMLNAVVCNRCYARAKRRSQRLAHPQTTTSLEKVDGASAPADADALGALCAAVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYB2</accession>
    <name>A4RYB2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418355.1">
        <property type="nucleotide sequence ID" value="XM_001418318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYB2"/>
    <dbReference type="GeneID" id="5002248"/>
    <dbReference type="Gramene" id="ABO96648">
        <property type="protein sequence ID" value="ABO96648"/>
        <property type="gene ID" value="OSTLU_24628"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24628"/>
    <dbReference type="HOGENOM" id="CLU_850984_0_0_1"/>
    <dbReference type="OMA" id="TYEVWHH"/>
    <dbReference type="OrthoDB" id="10426028at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="327" mass="36547" checksum="88747D0CC4D42EAE" modified="2007-05-15" version="1">MADVALRRCDCAPRRRLEILRAVREAFEREGDARAVAGDAGGMKRIAEAIARGIDDAATHVVVGRGDFNVNLRFAKKSLAYATARARGRRGSAGGKEAPEFRVLVFDSLSLGSGVDGTQQLAFQAMRDEHDEATETAKRRKGSATATVTSDVDGIPRAIVNTVLKVLSDADTADDDHDERASAIREELTRKFGSFWHVVSDEKDFAVASRATELPVQDGDDGEMKRISMRFRRKNCTYEVWHHVAPFDRYGFRKMTWAQKARYMRYFLIIFCACALVWYKYECAKDTHGVRRLVCRALPTLSPVAIGLFIFFVVSAHVDTSAWKKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYD5</accession>
    <name>A4RYD5_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418151.1">
        <property type="nucleotide sequence ID" value="XM_001418114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYD5"/>
    <dbReference type="GeneID" id="5002398"/>
    <dbReference type="Gramene" id="ABO96444">
        <property type="protein sequence ID" value="ABO96444"/>
        <property type="gene ID" value="OSTLU_31990"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31990"/>
    <dbReference type="eggNOG" id="ENOG502RYKC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016635_0_0_1"/>
    <dbReference type="OMA" id="WSRIMIN"/>
    <dbReference type="OrthoDB" id="496764at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="483"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="619"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="678"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="748"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="796"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="927" mass="101215" checksum="3AE81394520CFF52" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYG7</accession>
    <name>A4RYG7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein root UVB sensitive/RUS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_94434</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RUS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418386.1">
        <property type="nucleotide sequence ID" value="XM_001418349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYG7"/>
    <dbReference type="GeneID" id="5002261"/>
    <dbReference type="Gramene" id="ABO96679">
        <property type="protein sequence ID" value="ABO96679"/>
        <property type="gene ID" value="OSTLU_94434"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94434"/>
    <dbReference type="eggNOG" id="KOG4249">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_765902_0_0_1"/>
    <dbReference type="OMA" id="PKRWWAV"/>
    <dbReference type="OrthoDB" id="364779at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF27">
        <property type="entry name" value="PROTEIN ROOT UVB SENSITIVE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="3">
        <location>
            <begin position="3"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="362" mass="39143" checksum="F22D6C49D0E04E5F" modified="2007-05-15" version="1">MPELRRIFLPSGFPATTSADYVEWLRWQLLSLLFRDVLEIMSAQSLLVALGMGNTPGALPLTAAAKWVLKDGVGSFATLIAGSFGGQRYDEDPKRWWGLSNTLEDVARAIELVTPAAPGLFLPLAASATFVRAAALTGRGSLLNGTFMQHFGRNNNLGDIRAKLEVQGRWLALIALPAGIQVFQLVSAAAADLAADGDEFGAFVAAFGAYGGVIGVHVFACWQAAKSLKFDTLNRFRLLKLAEAFVANEDEELPDCVVVADMEGVYKPRRTATTPSYGASPSEIGEDWNAFTDAHATSRDMLAAALACQKLRVDETKSRSRAYAYADERVADFEASMIRSGWKVDYVQTGVAPRFAMSVDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYN1</accession>
    <name>A4RYN1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418419.1">
        <property type="nucleotide sequence ID" value="XM_001418382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYN1"/>
    <dbReference type="STRING" id="436017.A4RYN1"/>
    <dbReference type="GeneID" id="5002217"/>
    <dbReference type="Gramene" id="ABO96712">
        <property type="protein sequence ID" value="ABO96712"/>
        <property type="gene ID" value="OSTLU_94478"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94478"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_862182_0_0_1"/>
    <dbReference type="OMA" id="GWFNDLF"/>
    <dbReference type="OrthoDB" id="10250130at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052124">
        <property type="entry name" value="Rab9_kelch_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46647">
        <property type="entry name" value="RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46647:SF1">
        <property type="entry name" value="RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="323" mass="35194" checksum="12416BC483CFFD4E" modified="2007-05-15" version="1" fragment="single">MTRMRMEGYFVGTAAFVWEDEVYTYGGLAHEGEFVTSVYRWSGRGACYEVAATAADGEVGVPPGRYGHGAVVHGDLLYVFGGQGQFGCLNDLWVFDFVACTWTLVDVIGDPPPSRTGHCMCISDNVLFVFAGKDVQPGQDVVIYNDLYGFDLAESEWLTIDTQWKHPVGGDACAMAARNSTLYILSPNETSIEMVVWVLQLSAAGTPRWTMVARAGQVPSPRTSFLSCVYGANWIVHGGRVLLQDDVLGDTYVFHFPTAEWARLNPESDTDPRFSHAGACVDGALVILHGSRDPSIRASPEEAGVCIAINLEAYLPFPTGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ07</accession>
    <name>A4RZ07_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_6889</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418251.1">
        <property type="nucleotide sequence ID" value="XM_001418214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ07"/>
    <dbReference type="STRING" id="436017.A4RZ07"/>
    <dbReference type="GeneID" id="5002545"/>
    <dbReference type="Gramene" id="ABO96544">
        <property type="protein sequence ID" value="ABO96544"/>
        <property type="gene ID" value="OSTLU_6889"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6889"/>
    <dbReference type="eggNOG" id="KOG0813">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_4_1_1"/>
    <dbReference type="OMA" id="NYAYIFY"/>
    <dbReference type="OrthoDB" id="515692at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050110">
        <property type="entry name" value="Glyoxalase_II_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43705">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43705:SF1">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE GLOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="10">
        <location>
            <begin position="12"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="227" mass="24805" checksum="0356005A5BAAD927" modified="2007-05-15" version="1" fragment="single">AMDVLQFPALGDNYGFAVRCRKTKTVALVDAPDEGAIARALSSAGWESPSMILNTHHHRDHVGANGGVRARFPDARVVVVAPRREAEKIGDVDVAVEEGDVVEIGDVRATVRETPGHTLGHVVYHFEEEKKVFVGDTMFALGCGRLFEGTPAMMWASMQKLLAMSDDTQVYCAHEYTQSNAKFALSVDPTNEALRARAREIDALRAKGEPTVPTTIGLERLTNPFCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZD5</accession>
    <name>A4RZD5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="13">6.3.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">GSC2</name>
        <name evidence="15" type="ORF">OSTLU_41198</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer or monomer when oxidized or reduced, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Plastid</location>
            <location evidence="1 13">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="13"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418312.1">
        <property type="nucleotide sequence ID" value="XM_001418275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZD5"/>
    <dbReference type="STRING" id="436017.A4RZD5"/>
    <dbReference type="GeneID" id="5002446"/>
    <dbReference type="Gramene" id="ABO96605">
        <property type="protein sequence ID" value="ABO96605"/>
        <property type="gene ID" value="OSTLU_41198"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41198"/>
    <dbReference type="eggNOG" id="ENOG502QVEN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026610_1_0_1"/>
    <dbReference type="OMA" id="WADHLTT"/>
    <dbReference type="OrthoDB" id="2012853at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035434">
        <property type="entry name" value="GCL_bact_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011556">
        <property type="entry name" value="Glut_cys_lig_pln_type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01436">
        <property type="entry name" value="glu_cys_lig_pln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34378">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34378:SF1">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017901">
        <property type="entry name" value="GCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR017901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO96605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="484" mass="54784" checksum="A21635FA63BEC1B1" modified="2007-05-15" version="1">MTATTARGDALRVGTATRRGRRATRRATTTTIRAAATAPARAVTREECVAFVRRGCKPREAFRIGTEHEKFGYDEATKRRMDYPVVRHVLSSLVERHGWTPINEADNIIGCTKDKQSVTLEPGGQFELSGAPLENLTQTDEEVRWHIETVNALAREKGHRFLGIGFDPKWSVAEVPMMPKGRYKIMRAYMPKKGTRGHDMMFRTCTIQVNLDFESEQDMVRKFRTSLALQPLATAMFANSAFVDGADTGYQSMRSDVWRDTDDDRTGTLAWVFDDDFGFEKYCDYVMNVPMYFVYRNGTYVDVSGESWLDFMEGKLPQLPGDKPTIDDWEQHLTTVFPEVRLKKYMEMRGADGGSYEAIMALPALWVGLLYSDKALDAAEAMVSDWTQVERDALRVDVTKDGLSAKFRGGTANDIAKKMVELSVQGLQERGLGEEVYLRYLQDIVDDGKSVAARMSEMNAREWNGDLEKVYEYATFPDTLPKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZE7</accession>
    <name>A4RZE7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">indole-3-glycerol-phosphate synthase</fullName>
            <ecNumber evidence="3">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_32358</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="3"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418562.1">
        <property type="nucleotide sequence ID" value="XM_001418525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZE7"/>
    <dbReference type="STRING" id="436017.A4RZE7"/>
    <dbReference type="GeneID" id="5002370"/>
    <dbReference type="Gramene" id="ABO96855">
        <property type="protein sequence ID" value="ABO96855"/>
        <property type="gene ID" value="OSTLU_32358"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32358"/>
    <dbReference type="eggNOG" id="KOG4201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034247_1_0_1"/>
    <dbReference type="OMA" id="AGMHPAC"/>
    <dbReference type="OrthoDB" id="524799at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000024">
        <property type="entry name" value="Indole-3-glycerol phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001377">
        <property type="entry name" value="PRK00278.2-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854:SF2">
        <property type="entry name" value="INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="10">
        <location>
            <begin position="85"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="355" mass="38628" checksum="DE347BD8BC573A5A" modified="2007-05-15" version="1">MSAATGRATLATGARRDARRARRATRPRASAPSGVDDGAVSIRRRPPNGPSKHDLGVGQFEFVIEEVAPTGERVTNENNKPKNILEEIVWYKDVELAERKEKFPLQLVRTALVNAPPTRDFVKAITDQLAATKQPGLIAEVKKASPSKGVIQPNFDPVKIAKAYEEGGAACLSVLTDEKFFQGGFENLALIREAGVTCPLLCKEFIVDAYQIYLARKYGADAILLIAAVLPNQDLKYFIKIAHSLGMKCLIEVHTYGEMKRVLDGDFPIDLLGINNRDLGTFEVSLSVTTDLMNGPLGEEVKRRGITMVGESGIFTIDDVNLLQDSGVGAVLVGESLVKQDTPDVGIKKLFGRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZF3</accession>
    <name>A4RZF3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NCS1 family transporter: cytosine/purines/uracil/thiamine/allantoin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_49824</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418566.1">
        <property type="nucleotide sequence ID" value="XM_001418529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZF3"/>
    <dbReference type="GeneID" id="5002372"/>
    <dbReference type="Gramene" id="ABO96859">
        <property type="protein sequence ID" value="ABO96859"/>
        <property type="gene ID" value="OSTLU_49824"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49824"/>
    <dbReference type="eggNOG" id="KOG2466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021555_0_1_1"/>
    <dbReference type="OMA" id="GWNWRAV"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009526">
        <property type="term" value="C:plastid envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043100">
        <property type="term" value="P:pyrimidine nucleobase salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd11485">
        <property type="entry name" value="SLC-NCS1sbd_YbbW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="532" mass="55922" checksum="C2970C81C8E9BD40" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZP8</accession>
    <name>A4RZP8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LNS2/PITP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_19583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418833.1">
        <property type="nucleotide sequence ID" value="XM_001418796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZP8"/>
    <dbReference type="STRING" id="436017.A4RZP8"/>
    <dbReference type="GeneID" id="5002629"/>
    <dbReference type="Gramene" id="ABO97126">
        <property type="protein sequence ID" value="ABO97126"/>
        <property type="gene ID" value="OSTLU_19583"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19583"/>
    <dbReference type="eggNOG" id="KOG2116">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090871_1_0_1"/>
    <dbReference type="OMA" id="MVDAHIY"/>
    <dbReference type="OrthoDB" id="4567at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031315">
        <property type="entry name" value="LNS2/PITP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00775">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LNS2/PITP" evidence="1">
        <location>
            <begin position="39"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="252" mass="28255" checksum="6B61D32DD90257DB" modified="2007-05-15" version="1">MSLDLKPGTNTISFAFNSRVWGLQEVSAFVYLWDWNIKLVISDVDGTITKSDVLGHLAPMVGKDWSHDGVASLYSNITDNGYKMMFLTSRAISHASGTRKYLSSLRQGDKTLAQGPVMCAPDPLSKALFREVVTRNPQRFKIRCLQDIRNLFPPGWNPFHAGFGNRDTDVESYLAVGVPQHRVFTINPKGEVVCETTKRVKQYTLSEVNELAHEMFPPIEDTCPVTGSVAEEQFNDFNHWKNPVDADFGTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZT9</accession>
    <name>A4RZT9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">F-ATPase gamma subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_24766</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418858.1">
        <property type="nucleotide sequence ID" value="XM_001418821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZT9"/>
    <dbReference type="STRING" id="436017.A4RZT9"/>
    <dbReference type="GeneID" id="5002680"/>
    <dbReference type="Gramene" id="ABO97151">
        <property type="protein sequence ID" value="ABO97151"/>
        <property type="gene ID" value="OSTLU_24766"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24766"/>
    <dbReference type="eggNOG" id="KOG1531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050669_0_0_1"/>
    <dbReference type="OMA" id="VMQFEQD"/>
    <dbReference type="OrthoDB" id="239812at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.10:FF:000006">
        <property type="entry name" value="ATP synthase gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.80:FF:000003">
        <property type="entry name" value="ATP synthase gamma chain, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.80:FF:000004">
        <property type="entry name" value="ATP synthase gamma chain, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.80">
        <property type="entry name" value="ATP synthase, gamma subunit, helix hairpin domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004145">
        <property type="entry name" value="PRK05621.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF41">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="8" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="365" mass="39753" checksum="41579A1B4AA2E68A" modified="2007-05-15" version="1">MSAVAHTSLAMSKATAVRGASVKRSTAAQRATAPQRSLVIRNASPKEMRDRIASVGNTKKITDAMKLVAAAKVRKAQDAVIGARPFSESLVKVLFAINSRLAGEDVDVPLTKMRPVKTAMLVVCTGDRGLCGGFNNFIIRKTEQRVAELKAQGVECKLITVGKKGGVYFNRRKEQYNLVKRFDMGQAPSTQDAQTIADEIFAEFTSEEVDKVEMIYSRFVSLIAAEPTVQTILPLSKEGEVCNVDGVCIDAANDEIFKLTTEDGKFAVKREASDTEVSEFEGVMQFEQDPNQILDALMPLYMNSQILRALQESLASELAARMNAMSTASDNAKELKKTLSLVYNRARQAKITSEIIELVAGASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZZ3</accession>
    <name>A4RZZ3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418882.1">
        <property type="nucleotide sequence ID" value="XM_001418845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZZ3"/>
    <dbReference type="STRING" id="436017.A4RZZ3"/>
    <dbReference type="GeneID" id="5002819"/>
    <dbReference type="KEGG" id="olu:OSTLU_93004"/>
    <dbReference type="eggNOG" id="ENOG502QS29">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1565462_0_0_1"/>
    <dbReference type="OMA" id="ADDQLCG"/>
    <dbReference type="OrthoDB" id="515366at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="171" mass="18012" checksum="29600A1720448596" modified="2007-05-15" version="1" fragment="single">LAYSPVSVPALLESTMARGAEEGMTMDDDDDMSEDAKALVLENSAHEQLATFLRLCVATCGGGRGATARGDCWTWLFGAITVWVDAEGADESAPQRQAYELSEVRVVVKKGVAVDGEAAADQVLAGIDALVDADDQLCGKKNLYVRFGCRGDWPDLKPPGEYAGDAAAAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S037</accession>
    <name>A4S037_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_16113</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418676.1">
        <property type="nucleotide sequence ID" value="XM_001418639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S037"/>
    <dbReference type="GeneID" id="5002646"/>
    <dbReference type="Gramene" id="ABO96969">
        <property type="protein sequence ID" value="ABO96969"/>
        <property type="gene ID" value="OSTLU_16113"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16113"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013173_21_0_1"/>
    <dbReference type="OMA" id="FLRDNLM"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050688">
        <property type="term" value="P:regulation of defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="344" mass="37188" checksum="1E83F20E54D12C46" modified="2007-05-15" version="1">MDDGRLTTRVGAQDANGEEKLERAYSPSLRSGEHGEVGCREAMEDATVLDDNVPVEGARDVVAFYGVFDGHGGRAAAEFLRDNLMKNVVENENFMRDPELALKEAFLRTDEDFYDKSGPGETSGSTGLAACVIGGKLYIANAGDCRAVLSRKGKAIDLSIDQKPSSVGEMERIKNAGGFVEDGYVNGLLGVSRAFGDWHIEGLKGRGGKAGPVTVDPEIEKTRLTEDDEFLILACDGLWDVFSSQNAVDVARASLRQHNDPTITAKELAAEALRRDSSDNISVVCVCLTPEAPKKETFIRTSPSLLRSLSVEAMSIFPKRSRQNACKAFGTLQVTDELDPIPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0C3</accession>
    <name>A4S0C3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418948.1">
        <property type="nucleotide sequence ID" value="XM_001418911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0C3"/>
    <dbReference type="GeneID" id="5003037"/>
    <dbReference type="Gramene" id="ABO97241">
        <property type="protein sequence ID" value="ABO97241"/>
        <property type="gene ID" value="OSTLU_16178"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16178"/>
    <dbReference type="HOGENOM" id="CLU_750973_0_0_1"/>
    <dbReference type="OMA" id="DCADEIT"/>
    <dbReference type="OrthoDB" id="10582767at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673091" evidence="2">
        <location>
            <begin position="29"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="369" mass="39852" checksum="8160BA1BBE01BCB2" modified="2007-05-15" version="1">MATSRRRRARLGALVLACVAALAARARASDVDTECAEARRACARDARRAIDSDARLQKFLATATRDATRADGDAALGASRYGGFVADDAPRLAFAELVALGCCLFDGECARDAATRAARRGDDEAAATRDALEIGGALLFRASEHEHWTKMPGIGTLGADARTCAEATGTTRCDDALVATYVKAGDAGDELGVLRAGDAMLRRYVAGLATRVQGEGAREECDATRGGDVGDAAGARALFKRLLTSNRFDKVAAERLREVTRAEELWVDPTRGGTPDKAYLMADALIRLASRGATAIAVCVVFYVFRNFTFIGGAWRFARSVFLAVTGISLVTRVFKRVRAFVKWLRWKPPVVDTRQARREEARKSKKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0K1</accession>
    <name>A4S0K1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MC family transporter: succinate/fumarate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_16237</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418992.1">
        <property type="nucleotide sequence ID" value="XM_001418955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0K1"/>
    <dbReference type="STRING" id="436017.A4S0K1"/>
    <dbReference type="GeneID" id="5002832"/>
    <dbReference type="Gramene" id="ABO97285">
        <property type="protein sequence ID" value="ABO97285"/>
        <property type="gene ID" value="OSTLU_16237"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16237"/>
    <dbReference type="eggNOG" id="KOG0756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_5_0_1"/>
    <dbReference type="OMA" id="LPFQYQF"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005469">
        <property type="term" value="F:succinate:fumarate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015742">
        <property type="term" value="P:alpha-ketoglutarate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015746">
        <property type="term" value="P:citrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015743">
        <property type="term" value="P:malate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="133"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="231"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="35509" checksum="7700262337C7CEBD" modified="2007-05-15" version="1">MPAPANAYDVPALRRLRGAASASERTEKRSAARAAALLPLVKGVSGSFGGVIEACCLQPVDVVKTRLQLDKSGQYKGVVDCFKKIHAEEGVGALWKGLNAFATHLCFKYMLRMGTNATFQAALRDEEGKLTTGKRMAAGFGAGVVEALCIVTPFEVVKIRLQQQKGSVNLKYKGTLHAARTIMKEEGVMAMWNGAGPTIARNGTNQMCLFTAKAHVDSFLWGKHDGDGMALHPVQSLISGGLAATIGPVATGPFDVVKTRLMAQSKAGVIKYKSFLHALYLIPKEEGMLAMWKGLLPRLMRIPPGQAITFMVADGVVSHFEKSFSQEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0S1</accession>
    <name>A4S0S1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_35645</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419027.1">
        <property type="nucleotide sequence ID" value="XM_001418990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0S1"/>
    <dbReference type="STRING" id="436017.A4S0S1"/>
    <dbReference type="GeneID" id="5002849"/>
    <dbReference type="Gramene" id="ABO97320">
        <property type="protein sequence ID" value="ABO97320"/>
        <property type="gene ID" value="OSTLU_35645"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35645"/>
    <dbReference type="eggNOG" id="ENOG502RP77">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022752_2_0_1"/>
    <dbReference type="OMA" id="QPFKCGP"/>
    <dbReference type="OrthoDB" id="549173at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05388">
        <property type="entry name" value="CobB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03130">
        <property type="entry name" value="GATase1_CobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA/CobB_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002204">
        <property type="entry name" value="PRK01077.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="COBYRINATE A,C-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873:SF1">
        <property type="entry name" value="COBYRINATE A,C-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51274">
        <property type="entry name" value="GATASE_COBBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobQ/CobB/MinD/ParA nucleotide binding" evidence="7">
        <location>
            <begin position="4"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="CobB/CobQ-like glutamine amidotransferase" evidence="8">
        <location>
            <begin position="263"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="468" mass="50221" checksum="C045A341F32C0401" modified="2007-05-15" version="1" fragment="single">MKVVVVAGTHSGVGKTTIATALMLAYARRGLRVRAFKVGCDFVDPMAHRSALRSQSGDARESENLDGYMMSAGAVARVVAKHAETCDVAIVDGVMGLYDGRDGMSEDGSTAQMAKWLEAGVLLVVDCNAMARSVAAVIKGYREFDAELNLVGVVFNKTGGEAHTEYLRESLLAAMAHVDVFGGIPKDTNGPTFDPTSAATTSDDAMEQKIQHMAMLLEQNVDLDALFEAMPAYEISPRVARDLALERAMREELEAGPSKPKVRIAVARDEAFCFYYPENLAKLEDAGAELVYFSPIAGEGLPSDVQGVIFGGGYPEFHAQALFKNRPLRSAVTAFATAGGVVYAECGGLMFLSQSLSAPDGSSPRSMCGVAPFATRLTSSVKTGYAEITIAPGNPLFNEGEVVRGQTFRYSEIHGDRPSKMRQERKFGKGKNSINLDGFAWNNVLVSQLHLHFGANPSLASSFVESCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S145</accession>
    <name>A4S145_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_32968</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419089.1">
        <property type="nucleotide sequence ID" value="XM_001419052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S145"/>
    <dbReference type="STRING" id="436017.A4S145"/>
    <dbReference type="GeneID" id="5003352"/>
    <dbReference type="Gramene" id="ABO97382">
        <property type="protein sequence ID" value="ABO97382"/>
        <property type="gene ID" value="OSTLU_32968"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32968"/>
    <dbReference type="eggNOG" id="KOG2274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008920_1_0_1"/>
    <dbReference type="OMA" id="FINCIVT"/>
    <dbReference type="OrthoDB" id="431626at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056840">
        <property type="entry name" value="HEAT_IPO9_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058669">
        <property type="entry name" value="TPR_IPO7/11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="24"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="921"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="924"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1031" mass="111406" checksum="2DE0B7F69BD1EEC0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S156</accession>
    <name>A4S156_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419303.1">
        <property type="nucleotide sequence ID" value="XM_001419266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S156"/>
    <dbReference type="STRING" id="436017.A4S156"/>
    <dbReference type="GeneID" id="5003428"/>
    <dbReference type="Gramene" id="ABO97596">
        <property type="protein sequence ID" value="ABO97596"/>
        <property type="gene ID" value="OSTLU_32980"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32980"/>
    <dbReference type="HOGENOM" id="CLU_159612_0_0_1"/>
    <dbReference type="OMA" id="WGQAITR"/>
    <dbReference type="OrthoDB" id="191651at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
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        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="1">
        <location>
            <begin position="76"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="130" mass="15047" checksum="9F2C555897DEFA39" modified="2007-05-15" version="1">MALIRRAKAIANVAEAEKRDAERLRRAEQRWGQAITRDGRRYYFDKIERGTVQWECPRELKGTRTRTLRADVVESPTLPDGWRELRSETAEKIPYYWNMHTGLVQWERPRNEALAVAVVVPARAAGAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S175</accession>
    <name>A4S175_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial cardiolipin hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_7664</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the phospholipase D family. MitoPLD/Zucchini subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419316.1">
        <property type="nucleotide sequence ID" value="XM_001419279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S175"/>
    <dbReference type="STRING" id="436017.A4S175"/>
    <dbReference type="GeneID" id="5003405"/>
    <dbReference type="Gramene" id="ABO97609">
        <property type="protein sequence ID" value="ABO97609"/>
        <property type="gene ID" value="OSTLU_7664"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7664"/>
    <dbReference type="eggNOG" id="ENOG502RXG9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080814_0_2_1"/>
    <dbReference type="OrthoDB" id="5205528at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016891">
        <property type="term" value="F:RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09171">
        <property type="entry name" value="PLDc_vPLD6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051406">
        <property type="entry name" value="PLD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856">
        <property type="entry name" value="CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856:SF1">
        <property type="entry name" value="MITOCHONDRIAL CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="6">
        <location>
            <begin position="88"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="151" mass="17011" checksum="B3CB67A72E772470" modified="2007-05-15" version="1" fragment="single">CDKAHHTTSLVKFIRTLDKATSTLDVVCFTITCDDIKRAIQRAAKRGIRVRIVTDANNVDSLGSDIRELSEARKIDVRCDAHSNDPNKRGMMHHKFAIIDGETNDPVVITGSFNWTRAGVLDNHDNVLIARNQPDVAAPYIKHMEALWKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1T5</accession>
    <name>A4S1T5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_33214</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419422.1">
        <property type="nucleotide sequence ID" value="XM_001419385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1T5"/>
    <dbReference type="GeneID" id="5003120"/>
    <dbReference type="Gramene" id="ABO97715">
        <property type="protein sequence ID" value="ABO97715"/>
        <property type="gene ID" value="OSTLU_33214"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33214"/>
    <dbReference type="eggNOG" id="ENOG502SQYE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_317460_0_0_1"/>
    <dbReference type="OMA" id="QCCAPRT"/>
    <dbReference type="OrthoDB" id="435297at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673021" description="Beta-lactamase-related domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="4">
        <location>
            <begin position="68"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="897"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="527"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="920"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="983"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="992" mass="106558" checksum="AB55393DD4CC89D4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S215</accession>
    <name>A4S215_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_7335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419247.1">
        <property type="nucleotide sequence ID" value="XM_001419210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S215"/>
    <dbReference type="STRING" id="436017.A4S215"/>
    <dbReference type="GeneID" id="5003104"/>
    <dbReference type="Gramene" id="ABO97540">
        <property type="protein sequence ID" value="ABO97540"/>
        <property type="gene ID" value="OSTLU_7335"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7335"/>
    <dbReference type="eggNOG" id="KOG1203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1987354_0_0_1"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF11">
        <property type="entry name" value="OS06G0360300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="126" mass="13536" checksum="9D5DDD76A3781AF8" modified="2007-05-15" version="1" fragment="single">SRVDRDGVITCARACLRAGVERFVIVSSGAVSKPASPVYIFLNLFGGIMRNKILGEDAVRALYFDRPGQFYTVVRPGGLSEDPARGVGALELNQGDEISGRISREDVAAICIESITRDDAANATFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S244</accession>
    <name>A4S244_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29789</name>
        <name evidence="2" type="ORF">OSTLU_33320</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419471.1">
        <property type="nucleotide sequence ID" value="XM_001419434.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422951.1">
        <property type="nucleotide sequence ID" value="XM_001422914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S244"/>
    <dbReference type="GeneID" id="5003714"/>
    <dbReference type="GeneID" id="5007009"/>
    <dbReference type="Gramene" id="ABO97764">
        <property type="protein sequence ID" value="ABO97764"/>
        <property type="gene ID" value="OSTLU_33320"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01310">
        <property type="protein sequence ID" value="ABP01310"/>
        <property type="gene ID" value="OSTLU_29789"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29789"/>
    <dbReference type="KEGG" id="olu:OSTLU_33320"/>
    <dbReference type="HOGENOM" id="CLU_1322817_0_0_1"/>
    <dbReference type="OMA" id="KIRQCED"/>
    <dbReference type="OrthoDB" id="498444at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="208" mass="24058" checksum="6831F8141041E26C" modified="2007-05-15" version="1">MGSQNRTNKARTKREAVPNNAKARKQIAKLESAKKPGITYAQKRKAEKAARDTLKMSGNSARASNDQAMRREGGVKYGALEVRYRALAKKLRQIEDLERKRSEGTRMDAQQTKKLKRKEYLEAEMKNLEKLISGEAGDEEEEDEGEDDEEMSEEDEEEDDDDDDDDEEEEEDEDDEEEEEEDEDEDEEESSEEEDEDEDEEEDDSESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2B0</accession>
    <name>A4S2B0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Translation initiation factor IF-2, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Translation initiation factor IF-2, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MIF2</name>
        <name evidence="14" type="ORF">OSTLU_33386</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419720.1">
        <property type="nucleotide sequence ID" value="XM_001419683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2B0"/>
    <dbReference type="STRING" id="436017.A4S2B0"/>
    <dbReference type="GeneID" id="5003534"/>
    <dbReference type="Gramene" id="ABO98013">
        <property type="protein sequence ID" value="ABO98013"/>
        <property type="gene ID" value="OSTLU_33386"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33386"/>
    <dbReference type="eggNOG" id="KOG1145">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006301_5_1_1"/>
    <dbReference type="OMA" id="TIVCYQI"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000008">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="EF-G-like_DII"/>
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        <property type="entry name" value="IF2_II"/>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
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        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
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        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
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        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 14" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="13">
        <location>
            <begin position="161"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="419"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO98013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="683" mass="71912" checksum="41DEC0EE60D149EF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2N5</accession>
    <name>A4S2N5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="2">2.5.1.114</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_34943</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36355"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.5.1.114"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.114" evidence="2"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419563.1">
        <property type="nucleotide sequence ID" value="XM_001419526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2N5"/>
    <dbReference type="STRING" id="436017.A4S2N5"/>
    <dbReference type="GeneID" id="5003562"/>
    <dbReference type="Gramene" id="ABO97856">
        <property type="protein sequence ID" value="ABO97856"/>
        <property type="gene ID" value="OSTLU_34943"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34943"/>
    <dbReference type="eggNOG" id="KOG1227">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022610_1_0_1"/>
    <dbReference type="OMA" id="APGVWHV"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102522">
        <property type="term" value="F:tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000131">
        <property type="entry name" value="tRNA wybutosine-synthesizing protein 2/3/4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF25">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="8">
        <location>
            <begin position="19"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="30273" checksum="D6E5032F42ED65F7" modified="2007-05-15" version="1" fragment="single">MLEAKGLNVNLAQEAPTRWEKLGDLVLLPANAFTASDFSAFGAELYACVARVLGASRVARQAPVSQGPKRESRAVMLYPEGADGWVETKELGVTYGLDVTKVMFSSGNGTEKNRMGAVGANGETVVDLFAGIGYYTLQLLKNAGAAKVYACEWNPNSCEALRHNLRVNGVESRCEVLEGDNRRTAPTGVADRVLLGLLPHAEMSWETAIKALKPKGGVLHVHSNVNSGDEDEWMVRLVSELKSLAETNGRGDLDIVVEHLERVKWYGPRIRHVVCDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2U3</accession>
    <name>A4S2U3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase M3A/M3B catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_46518</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419806.1">
        <property type="nucleotide sequence ID" value="XM_001419769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2U3"/>
    <dbReference type="GeneID" id="5003757"/>
    <dbReference type="Gramene" id="ABO98099">
        <property type="protein sequence ID" value="ABO98099"/>
        <property type="gene ID" value="OSTLU_46518"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_46518"/>
    <dbReference type="eggNOG" id="KOG2089">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001805_2_1_1"/>
    <dbReference type="OMA" id="EPMLKNR"/>
    <dbReference type="OrthoDB" id="534666at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000074">
        <property type="entry name" value="Metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF82">
        <property type="entry name" value="THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="8">
        <location>
            <begin position="119"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="579" mass="64722" checksum="3F32AC74A17A7823" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3M5</accession>
    <name>A4S3M5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DnaJ homolog subfamily C member 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DnaJ homolog subfamily C member 16</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Endoplasmic reticulum DNA J domain-containing protein 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_5385</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays an important role in regulating the size of autophagosomes during the formation process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419948.1">
        <property type="nucleotide sequence ID" value="XM_001419911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3M5"/>
    <dbReference type="STRING" id="436017.A4S3M5"/>
    <dbReference type="GeneID" id="5003987"/>
    <dbReference type="Gramene" id="ABO98241">
        <property type="protein sequence ID" value="ABO98241"/>
        <property type="gene ID" value="OSTLU_5385"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5385"/>
    <dbReference type="eggNOG" id="KOG0191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1471893_0_0_1"/>
    <dbReference type="OrthoDB" id="498510at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052460">
        <property type="entry name" value="ER_disulfide_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44340">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44340:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="13"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="96"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="20253" checksum="29686509FFA9334F" modified="2007-05-15" version="1" fragment="single">VVRARLIVASSDDYYKLLGVDRNADERTLKKNYRIQALKHHPDKGGSPEHFAKISEAYEALTDPEKRRVYDQYGAEGLRNQQAGGHPGGGGGFGGGGFGHPGMRFDLRQGRFPGTDAKNIWFISFYAPWCGHCQQMKSQFEELAKALNGFVRVGAVNCEKQKGLCAMEGVDSYPTLKLKKAGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S411</accession>
    <name>A4S411_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_88482</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420190.1">
        <property type="nucleotide sequence ID" value="XM_001420153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S411"/>
    <dbReference type="STRING" id="436017.A4S411"/>
    <dbReference type="GeneID" id="5003975"/>
    <dbReference type="Gramene" id="ABO98483">
        <property type="protein sequence ID" value="ABO98483"/>
        <property type="gene ID" value="OSTLU_88482"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88482"/>
    <dbReference type="eggNOG" id="KOG0601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_25_0_1"/>
    <dbReference type="OMA" id="HARRANC"/>
    <dbReference type="OrthoDB" id="1335080at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF185">
        <property type="entry name" value="WEE1-LIKE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="213"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="468" mass="50840" checksum="DD93D7595B62E1A0" modified="2007-05-15" version="1">MDGERRARDDDDARDARSGGTRASASADEDGTNKSFDFAGCSQSQRDERRGATRGTARSQGNGESQEFGGPDFITPADAQFDAYGGYEDKENFRGARSPCALSPARNKRPRFGLDLGASQGTQEFASQPLDATQPSQSQGEFGGGFRVPRNREPTRGVGSRSGLPRAATSPPCARNAFLPDDEQPPETSAHARRANCTSAAQLATMSRFRADFVDLGCIARGGFSKVHKVIGRLDGCRYALKRTDKKLQTERERAEALREVQVLASLTQCAEIVRYQSAWWENDHLYIQMELCDGSASKMVDSQSGERASEAALMRCLLDVSAALSYAHARGLAHMDIKPDNIFIHNQGYKLGDWGRVALLNGDRRDAAVDEGDARYLSSEVLNDDFSALDRADIFSLGASIYELALGASLPSHGAEYQSLRRGVVPRVDVPARVHAFVLDAMSPTPSARPTAGRLHARVRAALDEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S419</accession>
    <name>A4S419_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_26251</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420016.1">
        <property type="nucleotide sequence ID" value="XM_001419979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S419"/>
    <dbReference type="STRING" id="436017.A4S419"/>
    <dbReference type="GeneID" id="5004106"/>
    <dbReference type="Gramene" id="ABO98309">
        <property type="protein sequence ID" value="ABO98309"/>
        <property type="gene ID" value="OSTLU_26251"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26251"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_450063_0_0_1"/>
    <dbReference type="OMA" id="GDEQLCH"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045191">
        <property type="entry name" value="MBR1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22937:SF65">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ARK2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22937">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="621"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="123"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="666" mass="74500" checksum="6662CFC919FC7782" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S422</accession>
    <name>A4S422_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_26255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420018.1">
        <property type="nucleotide sequence ID" value="XM_001419981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S422"/>
    <dbReference type="STRING" id="436017.A4S422"/>
    <dbReference type="GeneID" id="5004108"/>
    <dbReference type="Gramene" id="ABO98311">
        <property type="protein sequence ID" value="ABO98311"/>
        <property type="gene ID" value="OSTLU_26255"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26255"/>
    <dbReference type="eggNOG" id="KOG0127">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011608_2_0_1"/>
    <dbReference type="OMA" id="AGYVWDV"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12413">
        <property type="entry name" value="RRM1_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12414">
        <property type="entry name" value="RRM2_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12416">
        <property type="entry name" value="RRM4_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000182">
        <property type="entry name" value="RNA-binding motif protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
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<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
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                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001420281.1"/>
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    <dbReference type="GeneID" id="5004376"/>
    <dbReference type="Gramene" id="ABO98611">
        <property type="protein sequence ID" value="ABO98611"/>
        <property type="gene ID" value="OSTLU_26514"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SYZC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052657_1_0_1"/>
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    <dbReference type="OrthoDB" id="495821at2759"/>
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        <property type="component" value="Chromosome 11"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="HAD superfamily/HAD-like"/>
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    </dbReference>
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        <property type="entry name" value="SG protein - dephosphorylation function"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
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        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344:SF13">
        <property type="entry name" value="PHOSPHATASE RV3661-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="28936" checksum="8B908FD89A3C3158" modified="2007-05-15" version="1">MVGTTTRADASGTTARTAKGERRGVAFFDLDHTIIDVNSSWLWVKSEINSGRVGMSLIGTALYWFSRYAFGYGDGAETAGRDAASIYRGEDERMFRERITEFFRMELAHRTRPGFKAVLEAHKANGERCVMCTSTWQHPAAIGAEIYGLETGEANVVSSIMGVDEDGLMDGTIQVVAYGDGKYETTKKWCELNGVDLKECYFYTDSMSDVKLLENVGYPVCVNADARLKKHAAERGWPTVDWGMSDSGMKKPRYGACLSCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4U4</accession>
    <name>A4S4U4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec16 Sec23-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_26531</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420497.1">
        <property type="nucleotide sequence ID" value="XM_001420460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4U4"/>
    <dbReference type="STRING" id="436017.A4S4U4"/>
    <dbReference type="GeneID" id="5004384"/>
    <dbReference type="Gramene" id="ABO98790">
        <property type="protein sequence ID" value="ABO98790"/>
        <property type="gene ID" value="OSTLU_26531"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26531"/>
    <dbReference type="eggNOG" id="KOG1913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_273789_0_0_1"/>
    <dbReference type="OMA" id="WREHIAI"/>
    <dbReference type="OrthoDB" id="515854at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="7">
        <location>
            <begin position="588"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="881"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="987"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1079"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="904"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="940"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1087"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1119"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1174" mass="123450" checksum="BE2995F2BB6B59EF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Y1</accession>
    <name>A4S4Y1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_93468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420348.1">
        <property type="nucleotide sequence ID" value="XM_001420311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Y1"/>
    <dbReference type="STRING" id="436017.A4S4Y1"/>
    <dbReference type="GeneID" id="5004400"/>
    <dbReference type="Gramene" id="ABO98641">
        <property type="protein sequence ID" value="ABO98641"/>
        <property type="gene ID" value="OSTLU_93468"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93468"/>
    <dbReference type="eggNOG" id="ENOG502QPTI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075939_0_0_1"/>
    <dbReference type="OMA" id="TVCEREM"/>
    <dbReference type="OrthoDB" id="498485at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="entry name" value="Ribosomal protein L25, beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_bL25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_bL25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_bL25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_bL25_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_uL5_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33284">
        <property type="entry name" value="RIBOSOMAL PROTEIN L25/GLN-TRNA SYNTHETASE, ANTI-CODON-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33284:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L25_GLN-TRNA SYNTHETASE, ANTI-CODON-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL25 L25" evidence="5">
        <location>
            <begin position="40"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL25 beta" evidence="6">
        <location>
            <begin position="149"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="239" mass="25965" checksum="DA016826A58BA0D3" modified="2007-05-15" version="1">MWTIRRRLRTTRIASLTRDALARALATAPAGDDARGVVLRCALRVDGGTASSTRARREGRVPGVVFAPGSERGTMITVCEREMNAAVRKHTLAGVACEVFDLEVQTTTATGEESGETRRVRALAKQVQMHAYNQMVDNVCFLEVKPETEVKVRVPVATQGEDVSPGVKRGGFVQIMRQTVPVRCRSDSIPKRFLMDVSTLDAGKVIKIGDVTVPEGVKLLDADLNLPLVRIGGRVKSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5A8</accession>
    <name>A4S5A8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_10418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420574.1">
        <property type="nucleotide sequence ID" value="XM_001420537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5A8"/>
    <dbReference type="STRING" id="436017.A4S5A8"/>
    <dbReference type="GeneID" id="5004804"/>
    <dbReference type="Gramene" id="ABO98867">
        <property type="protein sequence ID" value="ABO98867"/>
        <property type="gene ID" value="OSTLU_10418"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10418"/>
    <dbReference type="eggNOG" id="KOG1635">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_1_1"/>
    <dbReference type="OMA" id="GRQICTE"/>
    <dbReference type="OrthoDB" id="497531at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774:SF1">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="5">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="170" mass="19259" checksum="29B7D130F4F1F53F" modified="2007-05-15" version="1" fragment="single">AVFAGGCFWCMTAPFETLDGVRAVTSGFIGGDVARPRYRDVGSGKTGHVESVRVVYDAAKTSYEKLLSVYWRQIDATRDDGQFVDAGKQYRPVIWAMDDAQKRAAEKSKEELERANVFGAPIKVEVVDASGMTFWPAERYHQDYYLKNPNRYRFYRAVSGRDEYIASVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5J5</accession>
    <name>A4S5J5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_26788</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420620.1">
        <property type="nucleotide sequence ID" value="XM_001420583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5J5"/>
    <dbReference type="STRING" id="436017.A4S5J5"/>
    <dbReference type="GeneID" id="5004649"/>
    <dbReference type="Gramene" id="ABO98913">
        <property type="protein sequence ID" value="ABO98913"/>
        <property type="gene ID" value="OSTLU_26788"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26788"/>
    <dbReference type="eggNOG" id="KOG1376">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015718_0_0_1"/>
    <dbReference type="OMA" id="YMASCIL"/>
    <dbReference type="OrthoDB" id="1844at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000004">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="9">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="10">
        <location>
            <begin position="248"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="447" mass="49136" checksum="6D5BE25720F135E8" modified="2007-05-15" version="1">MREVISIHIGQAGIQTGNSCWELYCLEHGIQPDGQMPSDASIGAEDDSFNTFFSETGAGKHVPRCIFLDLEPTVIDEVRTGAYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDVALDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSPAVSTAVVEPYNSVLSTHALLEHTDVSVMLDNEAVYDICRKSLDIERPTYTNLNRLLAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVAEITASAFEPASMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVANIKTKRTIQFVDWSPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNSTAIAEVFSRLDHKFDLMYGKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGASSVSDFPDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5R1</accession>
    <name>A4S5R1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="8">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_8108</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation. Oxidizes thioredoxin in vitro. Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space, and can act independently of the oxidoreductase MIA40. Can oxidize the cytochrome c oxidase assembly protein COX19, a typical substrate of MIA40.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:17358"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="8"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420816.1">
        <property type="nucleotide sequence ID" value="XM_001420779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5R1"/>
    <dbReference type="STRING" id="436017.A4S5R1"/>
    <dbReference type="GeneID" id="5004771"/>
    <dbReference type="Gramene" id="ABO99109">
        <property type="protein sequence ID" value="ABO99109"/>
        <property type="gene ID" value="OSTLU_8108"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8108"/>
    <dbReference type="eggNOG" id="KOG3355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070631_3_2_1"/>
    <dbReference type="OMA" id="FALWMCQ"/>
    <dbReference type="OrthoDB" id="17199at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.310:FF:000002">
        <property type="entry name" value="Sulfhydryl oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF0">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0274">FAD</keyword>
    <keyword evidence="2 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="9">
        <location>
            <begin position="3"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="110" mass="12492" checksum="A01CB4BB9C11A479" modified="2007-05-15" version="1" fragment="single">STTKTTKEDLGRATWTFLHTFAAQYPDEPTRRQERDARELIMILTRAYPCGECAAHFAEIVRVNPPDCSSGLALQRWMCAVHNEVNASLGKAWFDCAKVDGRWSKLECDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Y1</accession>
    <name>A4S5Y1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_26919</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420849.1">
        <property type="nucleotide sequence ID" value="XM_001420812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Y1"/>
    <dbReference type="STRING" id="436017.A4S5Y1"/>
    <dbReference type="GeneID" id="5004709"/>
    <dbReference type="Gramene" id="ABO99142">
        <property type="protein sequence ID" value="ABO99142"/>
        <property type="gene ID" value="OSTLU_26919"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26919"/>
    <dbReference type="eggNOG" id="KOG1257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011405_5_2_1"/>
    <dbReference type="OMA" id="AMWRILN"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <begin position="72"/>
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        </location>
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        <location>
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        </location>
        <ligand>
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        </ligand>
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            <position position="236"/>
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        </ligand>
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        </ligand>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="565" mass="62675" checksum="0FB5BC0E6DCDE09C" modified="2007-05-15" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
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                <person name="Jabbari K."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
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    </evidence>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S660</accession>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Manuell A."/>
                <person name="Tai V."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">CCE9901</strain>
        </source>
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        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="VOC"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="17"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="142" mass="16220" checksum="97179BBBD7023A5D" modified="2007-05-15" version="1">MRATRTKSLAEEIEIQGVHHVAVICDDLERSMAFYGGLLGLKINPERPEDKLPYRGAWLWIGPEMIHLMELPNPDCAHAEFRPTHGGRDRHFCIGVKRIQPLIDALERENIAYTASKSGRPAIFFRDPDCNTLEVVEGLEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S685</accession>
    <name>A4S685_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC(ATP-binding) family transporter: cobalt ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_6635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001421010.1"/>
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    <dbReference type="Gramene" id="ABO99340">
        <property type="protein sequence ID" value="ABO99340"/>
        <property type="gene ID" value="OSTLU_6635"/>
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    <dbReference type="KEGG" id="olu:OSTLU_6635"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
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        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:ATP hydrolysis activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
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        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
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        <property type="entry name" value="Molybdenum_import_ModC"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43514">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43514:SF4">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 10"/>
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    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
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    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="208" mass="22678" checksum="EF1DB464D90519C8" modified="2007-05-15" version="1" fragment="single">VRALRGASLRVPRGTLFMLLGPNGCGKSTLLRALAGLVKTDAGALEAPERKAFVFQNPDHQVIMPTVGADVGFGLGNDHTLSEDDVRERVVRALRTVNLTDDDAFERQVATLSGGQKQRVAIAGALVEEPELLLLDELTTFLDEADQRGVIEAVRRAVDESDGRVTALWVTHRLEELEFADGAAYMEDGVVVKLGTGKDIREFIREKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6M0</accession>
    <name>A4S6M0_OSTLU</name>
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        <recommendedName>
            <fullName evidence="7">DM10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_27168</name>
        <name evidence="9" type="ORF">OSTLU_36578</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABP01282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420971.1">
        <property type="nucleotide sequence ID" value="XM_001420934.1"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6M0"/>
    <dbReference type="STRING" id="436017.A4S6M0"/>
    <dbReference type="GeneID" id="5005177"/>
    <dbReference type="GeneID" id="5006900"/>
    <dbReference type="Gramene" id="ABO99264">
        <property type="protein sequence ID" value="ABO99264"/>
        <property type="gene ID" value="OSTLU_27168"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01282">
        <property type="protein sequence ID" value="ABP01282"/>
        <property type="gene ID" value="OSTLU_36578"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27168"/>
    <dbReference type="KEGG" id="olu:OSTLU_36578"/>
    <dbReference type="eggNOG" id="KOG0043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018366_2_0_1"/>
    <dbReference type="OMA" id="RFSCKQP"/>
    <dbReference type="OrthoDB" id="10255210at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="EF-hand domain containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.170">
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040193">
        <property type="entry name" value="EFHC1/EFHC2/EFHB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086">
        <property type="entry name" value="EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06565">
        <property type="entry name" value="DM10_dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DM10" evidence="7">
        <location>
            <begin position="52"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="7">
        <location>
            <begin position="193"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="7">
        <location>
            <begin position="367"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="472" mass="53634" checksum="D70A9967B2784301" modified="2007-05-15" version="1">MKPKTQSLSFVNGYAIPRDSDGEVDVFDANAFADAPARGEAKAYAPEYVKLHGLVLRFNAYFDETVENGQKESARCRKCVIYFFLEDGSIKITEPRVENSGMPQGAFLKRHVVRGVTLGDLNVGKAVTIYGFEFKIYRCDGFTRDYLGRVGVDVPNDEREPDGVGPSWEEVRLARRAARSTKKDARGKFLTHDKQVLRFYCVWDDRSKFGDRRRFVLTFFLIDDTVAITEVEANKSGRGSGMSSTLLHRSRLPLRDEDANARGLANDDFDYVTAEDLHVGDTIRVYKRDFFIYDCDEFTKSWYLTKFPGELTEAAFEPHDVTEPEDTVPAHRIPEHTGLAIGSEEDSLQNCISLIPKPPRKDVAKDDEIVLQFRAEMVPISDADEVCEFDASRRFVVSFHVGDKTLSIFEQASKDSCSSKFLERARVRKRDETGAFYDLRDMRVGSVLEIHSRAFKLGESDEFTRKYLENAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6R1</accession>
    <name>A4S6R1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_17898</name>
        <name evidence="6" type="ORF">OSTLU_19210</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421136.1">
        <property type="nucleotide sequence ID" value="XM_001421099.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422819.1">
        <property type="nucleotide sequence ID" value="XM_001422782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6R1"/>
    <dbReference type="STRING" id="436017.A4S6R1"/>
    <dbReference type="GeneID" id="5004992"/>
    <dbReference type="GeneID" id="5006965"/>
    <dbReference type="Gramene" id="ABO99429">
        <property type="protein sequence ID" value="ABO99429"/>
        <property type="gene ID" value="OSTLU_17898"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01178">
        <property type="protein sequence ID" value="ABP01178"/>
        <property type="gene ID" value="OSTLU_19210"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17898"/>
    <dbReference type="KEGG" id="olu:OSTLU_19210"/>
    <dbReference type="eggNOG" id="KOG0305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_929348_0_0_1"/>
    <dbReference type="OrthoDB" id="1589107at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="86"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP01178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="30935" checksum="7ABA806154068FCD" modified="2007-05-15" version="1" fragment="single">MANGGHRGVDVARRLIFEDSTRRGTGARDGSAPGTPEREGRASAGRGASAGRANAGYSDRYVPSRSASAGFRGDFSMLEACASVGVGATGGGRGEEIGGASGGGGGRIGRDGRGDADRGREGDANRDADSAGAHRGDGGSARAHEREDTSAAYGALLRSELLGDVCPPEAYGVTPPATPSAARYRPRTPATPIDGSSYSYSTPGRNLFKFRDDGSFGTIARGESPYALNPVGDGDGPLGMTLLSPRRRAPRKIARSPFKVLDAPALQDDFYLNLVDWSSSNVLAVGLGTCVYLWSACTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="115" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6S6</accession>
    <name>A4S6S6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_89011</name>
        <name evidence="12" type="ORF">OSTLU_89833</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421144.1">
        <property type="nucleotide sequence ID" value="XM_001421107.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422811.1">
        <property type="nucleotide sequence ID" value="XM_001422774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6S6"/>
    <dbReference type="GeneID" id="5005203"/>
    <dbReference type="GeneID" id="5006869"/>
    <dbReference type="Gramene" id="ABO99437">
        <property type="protein sequence ID" value="ABO99437"/>
        <property type="gene ID" value="OSTLU_89011"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01170">
        <property type="protein sequence ID" value="ABP01170"/>
        <property type="gene ID" value="OSTLU_89833"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89011"/>
    <dbReference type="KEGG" id="olu:OSTLU_89833"/>
    <dbReference type="eggNOG" id="KOG0768">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_3_0_1"/>
    <dbReference type="OMA" id="FDAIQMT"/>
    <dbReference type="OrthoDB" id="276989at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="210"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP01170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="313" mass="33044" checksum="FE0E179C1BF93730" modified="2007-05-15" version="1">MPPPSRVPADADRARARRETRRDASSSATDRPPSFARSLRVGIASGACAGIACQLVLFPLNTLKTRAQAGGRLTADRLYGGVAAELLGAAPGTALFMSAYECAKSTLGLDPSIAAMLGALASSAVLAPMELIARRMQVSRLSLATAARLSARRGELFAGFGSFLARELPFDTIQMSAFEAMKRATLAIEGAAADESGKKTKKKRALGKRQTAIIGGVAGGLTGLVTTPFDVSRTAHVCASSMGIDLKTHPKGLAGLKRLKERFGMSFFFRGAAPRALEIGLGGVIYFTVIETTRRYFESSSRETKDAKVLKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S717</accession>
    <name>A4S717_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MRH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_7884</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421194.1">
        <property type="nucleotide sequence ID" value="XM_001421157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S717"/>
    <dbReference type="STRING" id="436017.A4S717"/>
    <dbReference type="GeneID" id="5005381"/>
    <dbReference type="Gramene" id="ABO99487">
        <property type="protein sequence ID" value="ABO99487"/>
        <property type="gene ID" value="OSTLU_7884"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7884"/>
    <dbReference type="eggNOG" id="KOG2397">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094443_1_0_1"/>
    <dbReference type="OMA" id="NARHEFT"/>
    <dbReference type="OrthoDB" id="28322at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039794">
        <property type="entry name" value="Gtb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036607">
        <property type="entry name" value="PRKCSH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630:SF17">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630">
        <property type="entry name" value="N-LINKED OLIGOSACCHARIDE PROCESSING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13015">
        <property type="entry name" value="PRKCSH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MRH" evidence="3">
        <location>
            <begin position="44"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="140" mass="15721" checksum="FFC927182E7EDA06" modified="2007-05-15" version="1" fragment="single">AKSKRDAYDVERRALEANDDKLRELRENIDRDYGPDDALISLQGLCFDQKIEKYVYKACPFGEAKQDNTQLGRNSEGVRIDADGKTMTLKFADGDACWNGPKRSLTLTLKCGDKERLAAIEEPSRCEYVGVFYAPAACDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4S735</accession>
    <name>A4S735_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S735"/>
    <dbReference type="GeneID" id="5005389"/>
    <dbReference type="Gramene" id="ABO99497">
        <property type="protein sequence ID" value="ABO99497"/>
        <property type="gene ID" value="OSTLU_17994"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17994"/>
    <dbReference type="HOGENOM" id="CLU_1646534_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="161" mass="17005" checksum="463AA730622D0295" modified="2007-05-15" version="1">MVRSTDDMLDDLEAREPPGAVAAWALSKRAESVVGNPAVKKTVDVVGKVGVAAVRAAAPVVADGAGKVVKEGSKLAVKAAVSAATAKVGYDKREREKERSTPFGGLLGGNKKTPPLESEREKKKNPFAFPSLAKKPEPEPPRGLFGRKKDDKPKRGFFGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">DEP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421350.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S739"/>
    <dbReference type="GeneID" id="5005391"/>
    <dbReference type="Gramene" id="ABO99680">
        <property type="protein sequence ID" value="ABO99680"/>
        <property type="gene ID" value="OSTLU_27341"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27341"/>
    <dbReference type="eggNOG" id="ENOG502QS72">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012751_1_1_1"/>
    <dbReference type="OMA" id="RMAFFIN"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04371">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02066">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEP_dom"/>
    </dbReference>
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        <property type="entry name" value="DUF547"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ELECTRON CARRIER_ PROTEIN DISULFIDE OXIDOREDUCTASE"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="domain" description="DEP" evidence="2">
        <location>
            <begin position="203"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="555" mass="59735" checksum="B932159D764A5D7A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7G0</accession>
    <name>A4S7G0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_89136</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO99741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001421411.1"/>
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    <dbReference type="STRING" id="436017.A4S7G0"/>
    <dbReference type="GeneID" id="5005313"/>
    <dbReference type="Gramene" id="ABO99741">
        <property type="protein sequence ID" value="ABO99741"/>
        <property type="gene ID" value="OSTLU_89136"/>
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    <dbReference type="eggNOG" id="KOG4493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069661_1_0_1"/>
    <dbReference type="OMA" id="VCWEIWT"/>
    <dbReference type="OrthoDB" id="10259639at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
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    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:protein kinase binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="221" mass="24495" checksum="7864B38212649CDD" modified="2007-05-15" version="1">MRAREVFALPPLRCELSQVRDVLSALLHTIVFARALGCCAPRDARCERVDVHYVACGDGAVDGKIEEKINALVRWALKTGGGEADVAVSFYERERDKPRRGGALREALSGGRTRREEARAANGYWEQWRIGLEIFRGEELDETERARAREALRDQVVGTQRHVLGLVNEMKAHVPPVTTSDVVSFPFEISVPLARDDSPGSFGRDMLKRLASLGATPPSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7K9</accession>
    <name>A4S7K9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27532</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="gene ID" value="OSTLU_27532"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="61" mass="6884" checksum="199C2BDCFCB4FD6D" modified="2007-05-15" version="1">MSNILRAMSDGTPYNIIVKNPVQSEEPSDEPGEISEEPPVAEHYPSTVRFEEELKTNMSMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="3">BspA family leucine-rich repeat surface protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="1" type="ORF">OSTLU_2351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421440.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABO99770"/>
        <property type="gene ID" value="OSTLU_2351"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2351"/>
    <dbReference type="HOGENOM" id="CLU_999608_0_0_1"/>
    <dbReference type="OrthoDB" id="42699at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF03382">
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    </dbReference>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="32447" checksum="15E20E2E31E9B788" modified="2007-05-15" version="1" fragment="single">VSSVTFMLRMFQGASSFNQDIGNWDVRNVYNMEGMFYGASKFAQDISKWDSASVFDMSEAFSGARDFNGNIENWNVASVTSMFRMFYGARRFRGSLKLWNVAQVEDMNQMFSNAYKFNGDLGDWNVRSVTDFYKMFDDAWIDFNASIGSWNVAQVGTMVKMFQYATSFDQDLSSWNVKKVQNMQYMFNGARAFSRDLRKWTWDVSSVTTAYGMFHSTYFLNPSYRSPAWNTASATDMSEMFAYNRNFNQNLSDWNVSNVKSFHRMFAFAKSFNQDLNSW</sequence>
</entry>
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        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
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        <name evidence="8" type="ORF">OSTLU_27608</name>
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    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421327.1">
        <property type="nucleotide sequence ID" value="XM_001421290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7T2"/>
    <dbReference type="GeneID" id="5005227"/>
    <dbReference type="Gramene" id="ABO99620">
        <property type="protein sequence ID" value="ABO99620"/>
        <property type="gene ID" value="OSTLU_27608"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27608"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_273461_0_0_1"/>
    <dbReference type="OMA" id="SSAHWTF"/>
    <dbReference type="OrthoDB" id="507578at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat-containing domain"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="15"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="782"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="888"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="687"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="971" mass="104754" checksum="9CC6655ADB3D6986" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S855</accession>
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    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93767</name>
    </gene>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421668.1"/>
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        <property type="gene ID" value="OSTLU_93767"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG2293">
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    </dbReference>
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    <dbReference type="OrthoDB" id="10262769at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071339">
        <property type="term" value="C:MLL1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044545">
        <property type="term" value="C:NSL complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002151">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="FHA_MCRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FHA_dom"/>
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    </dbReference>
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        <property type="entry name" value="MCRS_N"/>
    </dbReference>
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        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="MICROSPHERULE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13233:SF0">
        <property type="entry name" value="MICROSPHERULE PROTEIN 1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="207"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="33280" checksum="218B49F864F49772" modified="2007-05-15" version="1">MPDPDLSRWPAIDDYLLKLACESGVALESLVGADSCVKFASVRTLDDVRARWNSMLRDDAFARACVRRLAEVRDDEIERAIAQRVAPRGATLREVLERAGLGTSRRRDGGAETEPESDDGAPPRFSRAEQAILRSDLVERTEAGRAAETKAKAKREVGRGANATTLKKIKALERSAQAATARLATAKGALAELVGANVTFEIAKRDCVIGRSTEDLKVDVDLGSEGNASKISRQQAFLKLRWNGEFALRNVGRRPIWCNNSPLTTGQRCILAPHTLIEVGGMRLLFLPNPTLIRAASPELLEKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S861</accession>
    <name>A4S861_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_40601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="OSTLU_40601"/>
    </dbReference>
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        <property type="component" value="Chromosome 15"/>
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        <property type="term" value="F:mRNA binding"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NEDD8 protein"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nedd8-like"/>
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        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="77" mass="8686" checksum="01862240EBC03351" modified="2007-05-15" version="1">MIKVKTLTGKEIEIDIEPTDSVERIKERVEEKEGIPPVQQRLIFGGKQMNDEKIAKDYNIEGGSVLHLVLALRGGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8F1</accession>
    <name>A4S8F1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_18354</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNU66/SART1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421608.1">
        <property type="nucleotide sequence ID" value="XM_001421571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8F1"/>
    <dbReference type="STRING" id="436017.A4S8F1"/>
    <dbReference type="GeneID" id="5005696"/>
    <dbReference type="Gramene" id="ABO99901">
        <property type="protein sequence ID" value="ABO99901"/>
        <property type="gene ID" value="OSTLU_18354"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18354"/>
    <dbReference type="eggNOG" id="KOG2217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_334159_0_0_1"/>
    <dbReference type="OMA" id="KRRDYTG"/>
    <dbReference type="OrthoDB" id="5583at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000481">
        <property type="term" value="P:maturation of 5S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005011">
        <property type="entry name" value="SNU66/SART1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152">
        <property type="entry name" value="SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152:SF5">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03343">
        <property type="entry name" value="SART-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="267"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="444"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="597"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="805"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="351"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="603"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="821"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="855" mass="93553" checksum="AD5CE44CFFA551D5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8J1</accession>
    <name>A4S8J1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyruvate phosphate dikinase AMP/ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421775.1">
        <property type="nucleotide sequence ID" value="XM_001421738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8J1"/>
    <dbReference type="GeneID" id="5005741"/>
    <dbReference type="Gramene" id="ABP00069">
        <property type="protein sequence ID" value="ABP00069"/>
        <property type="gene ID" value="OSTLU_25613"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25613"/>
    <dbReference type="eggNOG" id="ENOG502RE5K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002399_0_0_1"/>
    <dbReference type="OMA" id="FLHTGNW"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46999">
        <property type="entry name" value="ALPHA-GLUCAN WATER DIKINASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46999:SF2">
        <property type="entry name" value="CARBOHYDRATE-BINDING MODULE FAMILY 45 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="2">
        <location>
            <begin position="558"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="761" mass="82381" checksum="49DEC70D14029B12" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8T1</accession>
    <name>A4S8T1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_37686</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M76 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421812.1">
        <property type="nucleotide sequence ID" value="XM_001421775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8T1"/>
    <dbReference type="STRING" id="436017.A4S8T1"/>
    <dbReference type="MEROPS" id="M76.002"/>
    <dbReference type="GeneID" id="5005988"/>
    <dbReference type="Gramene" id="ABP00106">
        <property type="protein sequence ID" value="ABP00106"/>
        <property type="gene ID" value="OSTLU_37686"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37686"/>
    <dbReference type="eggNOG" id="KOG3314">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079125_3_0_1"/>
    <dbReference type="OMA" id="EAHQNCV"/>
    <dbReference type="OrthoDB" id="285308at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="168" mass="19198" checksum="52EACF72E948822C" modified="2007-05-15" version="1">MATRTSPIVRFMLQKLAEAGCAIDARFFSVETCDKSVVGGFRPPDGVVMCHNQIHDRTTMENMLAHELIHAYDQCRGGKKMNWLDVRQHACSEVRAANLSGDCHWMNELMRGRVFFDLKKHHQKCVRRRAELSVAMNPNCTSDAHAKQVVDEVFERCFKDTAPYDDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8U3</accession>
    <name>A4S8U3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_10376</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421818.1">
        <property type="nucleotide sequence ID" value="XM_001421781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8U3"/>
    <dbReference type="GeneID" id="5006108"/>
    <dbReference type="Gramene" id="ABP00112">
        <property type="protein sequence ID" value="ABP00112"/>
        <property type="gene ID" value="OSTLU_10376"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10376"/>
    <dbReference type="eggNOG" id="ENOG502S02U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_1_2_1"/>
    <dbReference type="OMA" id="KRMFGHF"/>
    <dbReference type="OrthoDB" id="440619at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00093">
        <property type="entry name" value="pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="4">
        <location>
            <begin position="62"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="26813" checksum="C3E7D883E62F5F42" modified="2007-05-15" version="1" fragment="single">RREADAAVSAGRVLVNGELVRPSQRVKAGDVVTLDGKVMLWEAYARRVEEEIANDATSSFVYLLYNKPRGVVCTMEPHQRTSLHFALERERARMKKIRIFPVGRLDKDSSGLVLLTNDGRVSDALLDPSRKAEKEYDVDVDRDVSAADVERLAAGVVITTLQQRTMTETTAPTQPCEVRKIGPRTLRFVLKEGRNRQIRKMCEALSYDVTRLHRTRIAELELGDLEIGGLRPLDVDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S950</accession>
    <name>A4S950_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DMT family transporter: glucose-6-phosphate/phosphate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_5074</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421872.1">
        <property type="nucleotide sequence ID" value="XM_001421835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S950"/>
    <dbReference type="GeneID" id="5006044"/>
    <dbReference type="Gramene" id="ABP00166">
        <property type="protein sequence ID" value="ABP00166"/>
        <property type="gene ID" value="OSTLU_5074"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5074"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048347_2_0_1"/>
    <dbReference type="OMA" id="NSLYTIW"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="9"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="281" mass="29528" checksum="111FFBA7DA72DDD6" modified="2007-05-15" version="1" fragment="single">ALTLSVVSSVSLVIVNKHLISILGFREVTFLTAMHMVLTALVLRAAARMGYFEKKSVGRAEVVKFGVLNSASIALLNLSLGFNSVGFYQMTKLSIIPVTVGLQITYFNKKFSAGVKMSLLVLLLGVGASTVTDVQLNATGSVVGGLSVVTTALGQILTGSMQQKHQISSTQLLCASAPWMAMTLMILAPPVDGVLNGGNILESRYSNEVLIVAFISCGLAIAVNFATFAVIGKCSAVTYQVVGHLKTMLILGFGFAVVGDPIVAKNVFGLLVALCGMFLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9B6</accession>
    <name>A4S9B6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422036.1">
        <property type="nucleotide sequence ID" value="XM_001421999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9B6"/>
    <dbReference type="GeneID" id="5006076"/>
    <dbReference type="Gramene" id="ABP00330">
        <property type="protein sequence ID" value="ABP00330"/>
        <property type="gene ID" value="OSTLU_18573"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18573"/>
    <dbReference type="HOGENOM" id="CLU_1987353_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="126" mass="12685" checksum="AD6C5BD38B00718F" modified="2007-05-15" version="1" fragment="single">MAPNGAKRRKASSPIAGEGAAKSAREDDDAGGDAREKMMTTTERDGDDDDGAGGGLVRVNADAEESYDDLTASALTGIEAHAIEAEAELQKARVASPSGKGGGKGASEDASAAASGTTKLDDKKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9J3</accession>
    <name>A4S9J3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CWC16 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422180.1">
        <property type="nucleotide sequence ID" value="XM_001422143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9J3"/>
    <dbReference type="STRING" id="436017.A4S9J3"/>
    <dbReference type="GeneID" id="5006136"/>
    <dbReference type="Gramene" id="ABP00497">
        <property type="protein sequence ID" value="ABP00497"/>
        <property type="gene ID" value="OSTLU_28221"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28221"/>
    <dbReference type="eggNOG" id="KOG2990">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050402_0_1_1"/>
    <dbReference type="OMA" id="RNMSVWD"/>
    <dbReference type="OrthoDB" id="360327at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="33607" checksum="C4B148CE131D12AF" modified="2007-05-15" version="1">MSTLAAVQADGFYYPPDWTPEGGAKNSAYKGSNGSLGKRANKLSQGVLTIRFEMPFNVKCGACGHMIAKGVRFNAEKRKIGKYHSTPIWSFTMHSACCSQEIEVQTDPAKTEYNVTKGAERCVGYGGAMDDEESPEDAMQMLEYQNEEERAKFLANPIAVLERGVEDEKRARARARTTFELNALSKARWKEDYDVNKSLRRSMRGRRKEEHALRDHARALGLPEHVKLEPERDEDKEYARRVFNASVFERNRKQKRKDILSESIFADKRTRPKPAAKRTSSASSNHSRAAKLAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9K4</accession>
    <name>A4S9K4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422084.1">
        <property type="nucleotide sequence ID" value="XM_001422047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9K4"/>
    <dbReference type="GeneID" id="5006142"/>
    <dbReference type="Gramene" id="ABP00401">
        <property type="protein sequence ID" value="ABP00401"/>
        <property type="gene ID" value="OSTLU_28232"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28232"/>
    <dbReference type="HOGENOM" id="CLU_005002_0_0_1"/>
    <dbReference type="OMA" id="QQHVRIN"/>
    <dbReference type="OrthoDB" id="2019763at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="897"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="989"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="394"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="517"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="817"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="909"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1010" mass="113443" checksum="08534B62B889057C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9U0</accession>
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            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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    </gene>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ABP00442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="5006183"/>
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        <property type="protein sequence ID" value="ABP00442"/>
        <property type="gene ID" value="OSTLU_41951"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome 17"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:ubiquitin protein ligase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of ERAD pathway"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="RNFT1/2"/>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
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        <property type="entry name" value="LP20373P"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR15860">
        <property type="entry name" value="UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
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        <location>
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            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP00442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="167" mass="18578" checksum="073D94FD74CF79FA" modified="2007-05-15" version="1">MPTARVYRRRASLLSTIEYANAACRTMIPAPVWLAYFKRELPSLFASFVTGLYVIFKLRGVVQRGFDFINAASMWLTASKRAGDIATSEDLMEAGDVCAICREPCVDATKLRCSHIFCEDCIGEWFDRQPSRGASREKTCPVCRAVVHSGTLKSFGDGSTQLSPLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAI0</accession>
    <name>A4SAI0_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001422399.1"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SWVN">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2642534_0_0_1"/>
    <dbReference type="OrthoDB" id="568307at2759"/>
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        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038789">
        <property type="entry name" value="LPA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37385">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37385:SF2">
        <property type="entry name" value="PROTEIN LPA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="77" mass="8284" checksum="C71567DC3FE63D00" modified="2007-05-15" version="1">MGQETEEAYVTFLFAYVGVIFVLGVVLGVSAFGKMPEAVDGFVSERLYPFFTPFVGGFLAFSSAYGVIKTRDDPNGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAL0</accession>
    <name>A4SAL0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Dynein-1, subspecies f</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">OSTLU_43542</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Force generating protein of eukaryotic cilia and flagella. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for assembly of the I1 inner arm complex and its targeting to the appropriate axoneme location. Also required for phototaxis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">The I1 inner arm complex (also known as the f dynein complex) is a two-headed isoform composed of two heavy chains (1-alpha and 1-beta), three intermediate chains and three light chains. I1 occupies a specific position proximal to the first radial spoke and repeats every 96 nm along the length of the axoneme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422630.1">
        <property type="nucleotide sequence ID" value="XM_001422593.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4SAL0"/>
    <dbReference type="GeneID" id="5006508"/>
    <dbReference type="Gramene" id="ABP00947">
        <property type="protein sequence ID" value="ABP00947"/>
        <property type="gene ID" value="OSTLU_43542"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43542"/>
    <dbReference type="eggNOG" id="KOG3595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000038_4_0_1"/>
    <dbReference type="OMA" id="ILKNDMQ"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036156">
        <property type="term" value="C:inner dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000153">
        <property type="entry name" value="Dynein axonemal heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000001">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000008">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000009">
        <property type="entry name" value="Dynein heavy chain 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056759">
        <property type="entry name" value="DYH2-5-8_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF32">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25007">
        <property type="entry name" value="DYH2-5-8_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="11 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="1722"/>
            <end position="1858"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="2002"/>
            <end position="2268"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="2339"/>
            <end position="2506"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="2701"/>
            <end position="2859"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="3166"/>
            <end position="3235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00054075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00063032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00077719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ABP00947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="4395" mass="495238" checksum="65B66453B3B30CEB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAR6</accession>
    <name>A4SAR6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Polyketide synthase dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422654.1">
        <property type="nucleotide sequence ID" value="XM_001422617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAR6"/>
    <dbReference type="GeneID" id="5006711"/>
    <dbReference type="Gramene" id="ABP00971">
        <property type="protein sequence ID" value="ABP00971"/>
        <property type="gene ID" value="OSTLU_29355"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29355"/>
    <dbReference type="eggNOG" id="ENOG502SBD5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1761842_0_0_1"/>
    <dbReference type="OMA" id="TVQVYKQ"/>
    <dbReference type="OrthoDB" id="495172at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide synthase dehydratase" evidence="2">
        <location>
            <begin position="97"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="148" mass="16456" checksum="AE0BBDE0DB1BA4B2" modified="2007-05-15" version="1">MASERAREEGEKPRYGLGEGPYALNEDDTAKDPVAFREALLEDQEKLKDIERDEALAKALLGEDTGAMQEALKKLVAIARHQAEQDSNYDMNSSDIMRARCTVPRDPTVLYQGMLKAGLQYGPSFRLLSQVWVPEALDREQREGGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB86</accession>
    <name>A4SB86_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Maf-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_43762</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422731.1">
        <property type="nucleotide sequence ID" value="XM_001422694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB86"/>
    <dbReference type="STRING" id="436017.A4SB86"/>
    <dbReference type="GeneID" id="5006633"/>
    <dbReference type="Gramene" id="ABP01048">
        <property type="protein sequence ID" value="ABP01048"/>
        <property type="gene ID" value="OSTLU_43762"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43762"/>
    <dbReference type="eggNOG" id="KOG1509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040416_0_2_1"/>
    <dbReference type="OMA" id="VIGCDSV"/>
    <dbReference type="OrthoDB" id="10267058at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF5">
        <property type="entry name" value="BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672285" description="Maf-like protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="23864" checksum="DBA5A3E751B28B07" modified="2007-05-15" version="1">MILHRLSALNALHVVLASASPRRREILRDVVGVECDIAPSAFAENLPHEDYDGAAAYARATAWMKAMDVYENWDANERGSEMPDVIIGADTVVESADGTTMEKPADAASATAMLRALSRSESKVHTGVAIIGGKISKKTGKIYGKSFSETTRVEFAELKAEEIAAYVATKEPYDKAGGYGIQGPAAVFIRGIVGDYFNVMGLPAHAFARELESMIDDVVEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBJ9</accession>
    <name>A4SBJ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_36776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422784.1">
        <property type="nucleotide sequence ID" value="XM_001422747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBJ9"/>
    <dbReference type="STRING" id="436017.A4SBJ9"/>
    <dbReference type="GeneID" id="5006936"/>
    <dbReference type="Gramene" id="ABP01143">
        <property type="protein sequence ID" value="ABP01143"/>
        <property type="gene ID" value="OSTLU_36776"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36776"/>
    <dbReference type="eggNOG" id="KOG0462">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017016_4_0_1"/>
    <dbReference type="OMA" id="MSMLFTI"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03691">
        <property type="entry name" value="BipA_TypA_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.250:FF:000001">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000002">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="entry name" value="bipa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048876">
        <property type="entry name" value="BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047042">
        <property type="entry name" value="BipA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21018">
        <property type="entry name" value="BipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="37"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="654" mass="70745" checksum="EA9A445F463B5DA8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQH5</accession>
    <name>A4RQH5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Brix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_40360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415733.1">
        <property type="nucleotide sequence ID" value="XM_001415696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQH5"/>
    <dbReference type="STRING" id="436017.A4RQH5"/>
    <dbReference type="GeneID" id="4999739"/>
    <dbReference type="KEGG" id="olu:OSTLU_40360"/>
    <dbReference type="eggNOG" id="KOG2780">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040063_1_1_1"/>
    <dbReference type="OMA" id="AWIISNK"/>
    <dbReference type="OrthoDB" id="10253204at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000002">
        <property type="entry name" value="Ribosome production factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="94"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="37029" checksum="CC09EE9918503935" modified="2007-05-15" version="1" fragment="single">LTSGIKNKQRRSEVYGKLRHERAVAKKQRRETRQKAEAAALEAGEEPAPRQIPKTIENQRVRDATHIDDLNDVDVVEQDAEDEFASYFSQATSPKIIITTSRKPSGDMFKFLENLFTVIPNAYYYARRNYQVKEIVKHGTARGFTDVLVFNENKKFSKGARVNGMLHVHLPEGPTCLYKLSSLKLSKEIKGHGRATSHYPELILNNFSTRLGHRVSRMFASVFPQKPEFKGRRVVTFHNQRDFIFFRHHRYVFEEKKDAEKPPPVNTMIQARLQELGPRFTLRLMSVQKGTFDSKHGEYEYVRSTDTDGTRHCRRKFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQV7</accession>
    <name>A4RQV7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tocopherol cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_39591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415456.1">
        <property type="nucleotide sequence ID" value="XM_001415419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQV7"/>
    <dbReference type="STRING" id="436017.A4RQV7"/>
    <dbReference type="GeneID" id="4999931"/>
    <dbReference type="Gramene" id="ABO93748">
        <property type="protein sequence ID" value="ABO93748"/>
        <property type="gene ID" value="OSTLU_39591"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39591"/>
    <dbReference type="eggNOG" id="ENOG502QQ9P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048962_0_0_1"/>
    <dbReference type="OMA" id="ERYECSI"/>
    <dbReference type="OrthoDB" id="38968at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009976">
        <property type="term" value="F:tocopherol cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025893">
        <property type="entry name" value="Tocopherol_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35309">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35309:SF4">
        <property type="entry name" value="TOCOPHEROL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14249">
        <property type="entry name" value="Tocopherol_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32004" checksum="361DCC0B5769181B" modified="2007-05-15" version="1" fragment="single">HRGRLTSEGESEEGPWGGGRAAKSVRWDITVTPLRGWGGGPGAKMVSPAGWMTALPVFEPHWQVTMAHGLASGWIETDGERVEFSDCPAYSEKNWGGAGFPLKWWWVQCNSFADYPDLSVTATGGNRGVVVLPNVREDVGLVGVHFGDRFFQFVPAQQASAVRWDVEWGRWSVTAVGERYECSIEGTCTNDDKSTVIRAPSDSLDEGMAPSCRETFTGVVVVSLWRLNDRGERVETIIDAATSDTACLEIGGGPWIGPWRSAAEIRSPLGPLMGLPVDVRAVASLLSPFGDVLPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQZ2</accession>
    <name>A4RQZ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_28834</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415476.1">
        <property type="nucleotide sequence ID" value="XM_001415439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQZ2"/>
    <dbReference type="STRING" id="436017.A4RQZ2"/>
    <dbReference type="GeneID" id="4999471"/>
    <dbReference type="Gramene" id="ABO93768">
        <property type="protein sequence ID" value="ABO93768"/>
        <property type="gene ID" value="OSTLU_28834"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28834"/>
    <dbReference type="HOGENOM" id="CLU_043875_0_0_1"/>
    <dbReference type="OMA" id="GCEDCDG"/>
    <dbReference type="OrthoDB" id="1939003at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="70"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="374" mass="40500" checksum="FBC2C03CD0B34BF3" modified="2007-05-15" version="1">MSFRVGAGENAEAEARNRAAAFTASAAFDAWVRGTKCVPGPKKAGLGGSRVRAKKHPYAYSGIMGDDIIDCVCGDNEEYGFMVACETCGAWEHGECCRIYAEEEIPKDYKCSSCVRRSEKVVVLLEFASDDKAASLRTAPTPVRSPEGDEIKDDYFGTIDGVAALLKEDRIAVCCVCGCEDCDGEYGSMIRACACDSGGAIAHESCMKNWSDKYSPQKAGNGRSRTTSRAPDTVRCKACGDVGGKASGVTEVAKLDEMLKAFGKAVDDTSSRYEAEAMAYRANPRPRPRTPVVETKPKKEKPKVEKKKVPAEKPAQTQAEAAPPTPKPSVKEEKFSGTPLSMLPLKKRRMMAWHSEQTGLSENVKHELKNNIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRB2</accession>
    <name>A4RRB2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Spindle assembly checkpoint component MAD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_28954</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415541.1">
        <property type="nucleotide sequence ID" value="XM_001415504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRB2"/>
    <dbReference type="STRING" id="436017.A4RRB2"/>
    <dbReference type="GeneID" id="4999846"/>
    <dbReference type="Gramene" id="ABO93833">
        <property type="protein sequence ID" value="ABO93833"/>
        <property type="gene ID" value="OSTLU_28954"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28954"/>
    <dbReference type="eggNOG" id="KOG4593">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_351738_0_0_1"/>
    <dbReference type="OMA" id="HRCHLLE"/>
    <dbReference type="OrthoDB" id="545678at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008672">
        <property type="entry name" value="Mad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168:SF0">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05557">
        <property type="entry name" value="MAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75704">
        <property type="entry name" value="Mitotic arrest deficient-like 1, Mad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="54"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="135"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO93833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="734" mass="81332" checksum="0999923D2EF40534" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRD7</accession>
    <name>A4RRD7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415883.1">
        <property type="nucleotide sequence ID" value="XM_001415846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRD7"/>
    <dbReference type="STRING" id="436017.A4RRD7"/>
    <dbReference type="GeneID" id="4999812"/>
    <dbReference type="Gramene" id="ABO94175">
        <property type="protein sequence ID" value="ABO94175"/>
        <property type="gene ID" value="OSTLU_28980"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28980"/>
    <dbReference type="eggNOG" id="KOG3326">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2516715_0_0_1"/>
    <dbReference type="OMA" id="HGREWIR"/>
    <dbReference type="OrthoDB" id="284292at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="entry name" value="Flavinator of succinate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="85" mass="9346" checksum="B0AED81EB5397E89" modified="2007-05-15" version="1">MASTTTTSDGFLDALDAVLDVENPELFKWLTAQETAPREMRENEAYASLAAHCAKFLDEKSSEASRAAHGREWIRGWNDSGAGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRK5</accession>
    <name>A4RRK5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415917.1">
        <property type="nucleotide sequence ID" value="XM_001415880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRK5"/>
    <dbReference type="GeneID" id="4999621"/>
    <dbReference type="Gramene" id="ABO94209">
        <property type="protein sequence ID" value="ABO94209"/>
        <property type="gene ID" value="OSTLU_13876"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13876"/>
    <dbReference type="HOGENOM" id="CLU_425397_0_0_1"/>
    <dbReference type="OMA" id="AETRCIT"/>
    <dbReference type="OrthoDB" id="102442at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="542" mass="62805" checksum="5C1104C55CDCDADD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="111" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRL2</accession>
    <name>A4RRL2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_12139</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415922.1">
        <property type="nucleotide sequence ID" value="XM_001415885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRL2"/>
    <dbReference type="STRING" id="436017.A4RRL2"/>
    <dbReference type="GeneID" id="4999438"/>
    <dbReference type="Gramene" id="ABO94214">
        <property type="protein sequence ID" value="ABO94214"/>
        <property type="gene ID" value="OSTLU_12139"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12139"/>
    <dbReference type="eggNOG" id="KOG1375">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015718_1_1_1"/>
    <dbReference type="OMA" id="PSAMMEN"/>
    <dbReference type="OrthoDB" id="563915at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000005">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="14">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="15">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO94214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="447" mass="49936" checksum="3B21FEADDF044E72" modified="2007-05-15" version="1">MREIVHIQAGQCGNQIGAKFWEVICDEHGIDPTGTYAGDADLQLERVNVYFNEASGGRYVPRAVLMDLEPGTMDSVRSGPYGQIFRPDNFVFGQTGAGNNWAKGHYTEGAELIDGVLDVVRKEAESCDCLQGFQMCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVVPSPKVSDTVVEPYNATLSVHQLVENADECMILDNEALYDICFRTLKLTTPTFGDLNHLISAVMSGVTCCLRFPGQLNADLRKLAVNLVPFPRLHFFMVGFTPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASALFRGRMSTKEVDEQLLNCQNKNSSYFVEWIPNNVKSSVCDIPPKGLKMSSTFIGNSTAIQEMFKRVSEAFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASAEEEGEFDEEDAEEAFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRL3</accession>
    <name>A4RRL3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_6400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. CGFS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415588.1">
        <property type="nucleotide sequence ID" value="XM_001415551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRL3"/>
    <dbReference type="STRING" id="436017.A4RRL3"/>
    <dbReference type="GeneID" id="5000054"/>
    <dbReference type="Gramene" id="ABO93880">
        <property type="protein sequence ID" value="ABO93880"/>
        <property type="gene ID" value="OSTLU_6400"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6400"/>
    <dbReference type="eggNOG" id="KOG0911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070932_1_0_1"/>
    <dbReference type="OMA" id="RNAPQCG"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:monoatomic cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF45">
        <property type="entry name" value="BIFUNCTIONAL MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="5">
        <location>
            <begin position="127"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="208" mass="23066" checksum="B8403832881C9A60" modified="2007-05-15" version="1" fragment="single">IPATAGVYAVYDERDALQYVGLSRKVNASVKVHAFEMPQYCYAVKCMALPDASKADLQAAWKTWVMEHVTTAGGLPPGNAPGNKLFSERRARPSKACLRLSDGKTPQMTADALKEAIGTCVREHKIVAFIKGTREEPDCGFSHRMINVLNELMVDYDTVNVLDDYYNPNLLFVIKDFSDWPTIPQLYVDGELLGGHDIVNSMHESGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="119" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRW9</accession>
    <name>A4RRW9_OSTLU</name>
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        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CYN71</name>
        <name evidence="10" type="ORF">OSTLU_40159</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415640.1">
        <property type="nucleotide sequence ID" value="XM_001415603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRW9"/>
    <dbReference type="STRING" id="436017.A4RRW9"/>
    <dbReference type="GeneID" id="4999944"/>
    <dbReference type="Gramene" id="ABO93932">
        <property type="protein sequence ID" value="ABO93932"/>
        <property type="gene ID" value="OSTLU_40159"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40159"/>
    <dbReference type="eggNOG" id="KOG0882">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_31_2_1"/>
    <dbReference type="OMA" id="GMVEYWR"/>
    <dbReference type="OrthoDB" id="10264753at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010338">
        <property type="term" value="P:leaf formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010358">
        <property type="term" value="P:leaf shaping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010305">
        <property type="term" value="P:leaf vascular tissue pattern formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009933">
        <property type="term" value="P:meristem structural organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010082">
        <property type="term" value="P:regulation of root meristem growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01927">
        <property type="entry name" value="cyclophilin_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="61"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="9">
        <location>
            <begin position="479"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO93932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="629" mass="69527" checksum="21FA0629182B90FC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRX9</accession>
    <name>A4RRX9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415644.1">
        <property type="nucleotide sequence ID" value="XM_001415607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRX9"/>
    <dbReference type="GeneID" id="4999766"/>
    <dbReference type="Gramene" id="ABO93936">
        <property type="protein sequence ID" value="ABO93936"/>
        <property type="gene ID" value="OSTLU_29175"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29175"/>
    <dbReference type="eggNOG" id="KOG4498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1356860_0_0_1"/>
    <dbReference type="OMA" id="WEHASEL"/>
    <dbReference type="OrthoDB" id="40334at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630:SF3">
        <property type="entry name" value="PEROXIREDOXIN-LIKE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="200" mass="21552" checksum="760942BDA7FFAF7B" modified="2007-05-15" version="1">MTSAASGTTRVNVPSDAPSDALEALRAVEVMRAIDGARVTVPEVVGARGTVVRAVELARDAIPTLDAAGVRLVVVSIGTLERAKDFSRENDFPIELLYADAESATYEALKLRKGAKQTFMEKSTPESILKRWNKDGAKDLLGVLKRWKPWLPPRPDQGYQQGGSFVFRDGVATYVSYDVSTGAHAPLDDIFEAAGVSTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSC7</accession>
    <name>A4RSC7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_92343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416272.1">
        <property type="nucleotide sequence ID" value="XM_001416235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSC7"/>
    <dbReference type="GeneID" id="5000370"/>
    <dbReference type="Gramene" id="ABO94565">
        <property type="protein sequence ID" value="ABO94565"/>
        <property type="gene ID" value="OSTLU_92343"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92343"/>
    <dbReference type="HOGENOM" id="CLU_1181852_0_0_1"/>
    <dbReference type="OrthoDB" id="10607774at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
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        <location>
            <begin position="54"/>
            <end position="120"/>
        </location>
    </feature>
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            <begin position="1"/>
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            <end position="92"/>
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            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="25271" checksum="82A15A5B30C8F520" modified="2007-05-15" version="1">MAWQSRVRDMERAYEQSTTSIATARRRGATKSRDIGRGLQKDYVNMIRDDVESASGDRAKTFATNGVSSSTAAAADSGTPSKDPELKVRDGDVGASVDDESARSGREDVPGLDDFGPVAVDDDEEPVLTRLKPNEDVRRPSLLLRALDFSRRVGLIGASILFGIFLVFVAMSVYEEMQTSGNHDPLRPKFAPGVAVTVDERTVAEEAAARGESAKNAFLDVEREAGVDGASAMNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="GO" id="GO:0005852">
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:translation initiation factor activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
    <feature type="domain" description="Eukaryotic translation initiation factor 3 subunit C N-terminal" evidence="5">
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        </location>
    </feature>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
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            <dbReference type="Pfam" id="PF05470"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="863" mass="97556" checksum="449A8936B7E3AD3B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
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                <person name="Putnam N."/>
                <person name="Dupont C."/>
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                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Gramene" id="ABO94721">
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        <property type="gene ID" value="OSTLU_119565"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119565"/>
    <dbReference type="HOGENOM" id="CLU_1470526_0_0_1"/>
    <dbReference type="OrthoDB" id="19768at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="20226" checksum="912C80526D866B84" modified="2007-05-15" version="1">MGSRNTWTETESRILAQELRRSASDPQTSHLATCVSIAALLPNKLARDVAIRVRWLKGNSEIPTAQFSSKLPLGDFIEMRRFNSHATNVGVGTDTLGLGYSRGDGEPAILSIEKLLKENTTLLERFECARTGADVSQADLKMILDNLFAIDSLIRSRYDNGKTMPRMPVRVDVSLVAAVFGLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSX9</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="primary">Cup200</name>
        <name evidence="1" type="ORF">OSTLU_119537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416130.1"/>
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    <dbReference type="STRING" id="436017.A4RSX9"/>
    <dbReference type="GeneID" id="5000310"/>
    <dbReference type="Gramene" id="ABO94460">
        <property type="protein sequence ID" value="ABO94460"/>
        <property type="gene ID" value="OSTLU_119537"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119537"/>
    <dbReference type="HOGENOM" id="CLU_1940927_0_0_1"/>
    <dbReference type="OMA" id="LRIRECV"/>
    <dbReference type="OrthoDB" id="506252at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36391">
        <property type="entry name" value="FURRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36391:SF1">
        <property type="entry name" value="FURRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="135" mass="15141" checksum="E6F4B51FD8D4D820" modified="2007-05-15" version="1">MTTRKLGVGVAQNFSNSQRLRVLAPWGFTGPVSDVEWRDVPVRADEYRSQSPASSSQVVVPQTTTSKVYATRYYIRDSRRNNVSELHGSTFTTTKISKETLRDLANTPMDSGQYYGRLRIRECVSLLDDPSAGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT42</accession>
    <name>A4RT42_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tubulin gamma chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TubG</name>
        <name evidence="12" type="ORF">OSTLU_119480</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles, suggesting that it is involved in the minus-end nucleation of microtubule assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416381.1">
        <property type="nucleotide sequence ID" value="XM_001416344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT42"/>
    <dbReference type="STRING" id="436017.A4RT42"/>
    <dbReference type="GeneID" id="5000164"/>
    <dbReference type="Gramene" id="ABO94674">
        <property type="protein sequence ID" value="ABO94674"/>
        <property type="gene ID" value="OSTLU_119480"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119480"/>
    <dbReference type="eggNOG" id="KOG1374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015718_1_0_1"/>
    <dbReference type="OMA" id="HRYISIL"/>
    <dbReference type="OrthoDB" id="10249382at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02188">
        <property type="entry name" value="gamma_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000004">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000010">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002454">
        <property type="entry name" value="Gamma_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01164">
        <property type="entry name" value="GAMMATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="10">
        <location>
            <begin position="51"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="11">
        <location>
            <begin position="252"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="449" mass="49856" checksum="4CF0A3FD1748CBF5" modified="2007-05-15" version="1">MPREIVTIQIGQCGNQVGTEFWNQLCTEHGISMDGTCRIDGASVNMFSDRKDVFFYQADDEHYVPRALLLDLEPRVINSIQTSTQRSLFNTENFFTSAHGGGAGNNWANGYTQAEAVHEELMEMIDREVDGSDSLAGFVICHSIAGGTGSGMGSYLLEALSDRYGKKLLQTYSVFPNQSESSDVVVQPYNSLLTLKRLTNHADCVVVLDNAALNRIAMDHLHVASPDFSHTNSLVSKVMAASTTTLRYPGYMNNDLVGLIASLIPIPRCNFLMAGLTPLAGVSATESSTRKTSTLDVMRRLLQSKNVMCSSYAGTGVKEGKFISILNIVQGNIEPMQIHKSLQRIRERKLANFITWAPVNYQVALARSSPYIAKTASLNGLMLANHTSIRHWFSRSLEQYDKLIRRRAFLDQYEQFDLFSDLGEFADSQEAVENLVEEYRVCEAGPSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT95</accession>
    <name>A4RT95_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_35807</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416113.1">
        <property type="nucleotide sequence ID" value="XM_001416076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT95"/>
    <dbReference type="STRING" id="436017.A4RT95"/>
    <dbReference type="GeneID" id="5000133"/>
    <dbReference type="Gramene" id="ABO94405">
        <property type="protein sequence ID" value="ABO94405"/>
        <property type="gene ID" value="OSTLU_35807"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35807"/>
    <dbReference type="eggNOG" id="KOG0201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="NECKHEN"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="6"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="281" mass="30714" checksum="3C45A64691A4BDFF" modified="2007-05-15" version="1" fragment="single">MIDDRYVLLAKVGRGATGEVYKARDVRTDATVAVKLVDLEDAEDDVADIQREISTLAQCASPYVTKYLASALVRGTSKLAIVMEYMAGGSARHLADEAAKGEGETTAIEDEAKVGLEEGEISYITRDVLRALEYLHEEGKIHRDVKAANVLLTEGGEARLADFGVSGQMTHTLGARRKTFTGTPFWMAPEVIQGGEGYDEKADIWSLGITCYELALGAAPHADLHPMRVLFVIPKNDAPRLPDDGRFSADFQDFVAKCLQKDAKARPSARELLNHPFAKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU26</accession>
    <name>A4RU26_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416597.1">
        <property type="nucleotide sequence ID" value="XM_001416560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU26"/>
    <dbReference type="STRING" id="436017.A4RU26"/>
    <dbReference type="GeneID" id="5000829"/>
    <dbReference type="Gramene" id="ABO94890">
        <property type="protein sequence ID" value="ABO94890"/>
        <property type="gene ID" value="OSTLU_24196"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24196"/>
    <dbReference type="HOGENOM" id="CLU_429228_0_0_1"/>
    <dbReference type="OMA" id="GEHAAPW"/>
    <dbReference type="OrthoDB" id="10250769at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="638" mass="67469" checksum="7DF47214ECC8E35F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU32</accession>
    <name>A4RU32_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_30478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416601.1">
        <property type="nucleotide sequence ID" value="XM_001416564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU32"/>
    <dbReference type="GeneID" id="5001129"/>
    <dbReference type="Gramene" id="ABO94894">
        <property type="protein sequence ID" value="ABO94894"/>
        <property type="gene ID" value="OSTLU_30478"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30478"/>
    <dbReference type="HOGENOM" id="CLU_1148840_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="159"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="85"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="103"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="242" mass="25431" checksum="759BCCDC0EF1F713" modified="2007-05-15" version="1">MNAYDSIERGAADECEPLTGRRPRTFTLTQLLVACGAVCVCAIGATMFVNTHAQLADAGYGGDSIQSSGCPIQDWVDDSLCAASPPGLSESKSRGRALLGSRNTSSETSIDTSSDTSSETSIDNTSSDTSSDTSSDTSSSNQVSIPSCAKIPPRPKSSDSVSCNGHGWCHEGTTASGNKPHCDCNAGYGGSHCETKILNLEDLSIKVADIEEEMEKMAESAVETIKLEEQPLLHEHGHEHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU43</accession>
    <name>A4RU43_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_7195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416892.1">
        <property type="nucleotide sequence ID" value="XM_001416855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU43"/>
    <dbReference type="STRING" id="436017.A4RU43"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="GeneID" id="5000992"/>
    <dbReference type="Gramene" id="ABO95185">
        <property type="protein sequence ID" value="ABO95185"/>
        <property type="gene ID" value="OSTLU_7195"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7195"/>
    <dbReference type="eggNOG" id="ENOG502S8BV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_17_3_1"/>
    <dbReference type="OMA" id="QMPYGDQ"/>
    <dbReference type="OrthoDB" id="191769at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02522">
        <property type="entry name" value="GT_2_like_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026461">
        <property type="entry name" value="Trfase_2_rSAM/seldom_assoc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04283">
        <property type="entry name" value="glyco_like_mftF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43646">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43646:SF2">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="6">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="242" mass="26712" checksum="A35A487ADCBCBFC5" modified="2007-05-15" version="1" fragment="single">ASFTVVIPALNEETRVREAIASARANASARVIVVDGGSTDATVRVARKHGASVVRSERGRGRQMNAGAAAAAATGTRDASDVLVFLHADSTLPTGYGELITRALAKRVTGRSREWGAFEFKMGGEREDEGFARTCTRRAIEFGTNARCRLFRMPYGDQALVMRRETFDSVGGFDELPFMEDYIMARKLRRRGAPALFSAPVTTSGRRWDERGFSKVTLMNQVIILGYHIGVPMEKLAEWYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="106" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUN3</accession>
    <name>A4RUN3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CCT-theta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_34150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416701.1">
        <property type="nucleotide sequence ID" value="XM_001416664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUN3"/>
    <dbReference type="STRING" id="436017.A4RUN3"/>
    <dbReference type="GeneID" id="5000635"/>
    <dbReference type="Gramene" id="ABO94994">
        <property type="protein sequence ID" value="ABO94994"/>
        <property type="gene ID" value="OSTLU_34150"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34150"/>
    <dbReference type="eggNOG" id="KOG0362">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_4_2_1"/>
    <dbReference type="OMA" id="WGLKYAV"/>
    <dbReference type="OrthoDB" id="1748577at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051050">
        <property type="term" value="P:positive regulation of transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03341">
        <property type="entry name" value="TCP1_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000008">
        <property type="entry name" value="T-complex protein 1 subunit theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012721">
        <property type="entry name" value="Chap_CCT_theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02346">
        <property type="entry name" value="chap_CCT_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="541" mass="58116" checksum="C16EDF2050006E6D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV66</accession>
    <name>A4RV66_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribosomal protein L12, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPL12</name>
        <name evidence="8" type="ORF">OSTLU_34409</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416788.1">
        <property type="nucleotide sequence ID" value="XM_001416751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV66"/>
    <dbReference type="STRING" id="436017.A4RV66"/>
    <dbReference type="GeneID" id="5000813"/>
    <dbReference type="Gramene" id="ABO95081">
        <property type="protein sequence ID" value="ABO95081"/>
        <property type="gene ID" value="OSTLU_34409"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34409"/>
    <dbReference type="eggNOG" id="KOG0886">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_5_0_1"/>
    <dbReference type="OMA" id="QPPHDVI"/>
    <dbReference type="OrthoDB" id="10250051at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="7">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="6">
        <location>
            <begin position="75"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="166" mass="17635" checksum="AEE768FF7EC1A87C" modified="2007-05-15" version="1">MPPKFDPNSVLEIFMRATGGEVGAASSLAPKIGPLGLSPKKVGEDIAKETAKDWKGLRVTVKLTVQNRQAKVSVVPTASALVIKALKEPFQDRKKVKGILHTGNCSLDDIIEVARTMRPRSCAKSLAGTVKEILGTAKSVGCTVEGEDPSDVQESIDSGDIEIPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV95</accession>
    <name>A4RV95_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_30894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416803.1">
        <property type="nucleotide sequence ID" value="XM_001416766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV95"/>
    <dbReference type="STRING" id="436017.A4RV95"/>
    <dbReference type="CAZy" id="GT7">
        <property type="family name" value="Glycosyltransferase Family 7"/>
    </dbReference>
    <dbReference type="GeneID" id="5000956"/>
    <dbReference type="Gramene" id="ABO95096">
        <property type="protein sequence ID" value="ABO95096"/>
        <property type="gene ID" value="OSTLU_30894"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30894"/>
    <dbReference type="eggNOG" id="KOG3916">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_793189_0_0_1"/>
    <dbReference type="OMA" id="MVKWEAL"/>
    <dbReference type="OrthoDB" id="508846at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008378">
        <property type="term" value="F:galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003859">
        <property type="entry name" value="Galactosyl_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300">
        <property type="entry name" value="BETA-1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300:SF57">
        <property type="entry name" value="BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02050">
        <property type="entry name" value="B14GALTRFASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="350" mass="38960" checksum="8FFF25826C42FB0F" modified="2007-05-15" version="1">MTLRLVLLVPFREDATRTRAAQLRQLIERFVAVFDDPSRPALVVVCEQSDDGCRFNRGQCLNAAYAIATSTFSERIDRCGTHFACHDVDMAPEAATKTAYFVEDDARDGAGFVRVLQASGCRYDAEKCFGGVTIYDVTAFERTNGYPNGFYGWGGEDHAAFLRAAEAGVRVERRSGAAFDDLEKDVETVAKKLSVLDAHDARINAKEKERLLKRNAKFWREDGLNSCAFDVVEKSVLRESPALTCVQFKVELKCARPGYIKCFTCATWLPEPEYSGKALAAVRWSEKTGTKHERSCTSCTANLPKQIETEAQKAFNQSNFEQRLTCAECATLFASRTSLFKHLKSSPCGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVE6</accession>
    <name>A4RVE6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_37128</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417410.1">
        <property type="nucleotide sequence ID" value="XM_001417373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVE6"/>
    <dbReference type="STRING" id="436017.A4RVE6"/>
    <dbReference type="GeneID" id="5001485"/>
    <dbReference type="Gramene" id="ABO95703">
        <property type="protein sequence ID" value="ABO95703"/>
        <property type="gene ID" value="OSTLU_37128"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37128"/>
    <dbReference type="eggNOG" id="KOG1735">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094004_2_2_1"/>
    <dbReference type="OMA" id="SECRYAI"/>
    <dbReference type="OrthoDB" id="494827at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11286">
        <property type="entry name" value="ADF_cofilin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="142" mass="15953" checksum="D1E9ED14AA090209" modified="2007-05-15" version="1">MSGVAVAEDCLSVFNKVKMRSNGLQWATFRVEENEGSVLTAATGEVSGDYDDFIAALPESECRYAIYDYKYVNADDCEFSKLVFVVWNPDSARLKNKMLYASTKDFFKSRLSGIAVEIQATDYDEVSEAELRENIGITLTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVQ8</accession>
    <name>A4RVQ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Selenoprotein F/M domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the selenoprotein M/F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417455.1">
        <property type="nucleotide sequence ID" value="XM_001417418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVQ8"/>
    <dbReference type="GeneID" id="5001203"/>
    <dbReference type="Gramene" id="ABO95748">
        <property type="protein sequence ID" value="ABO95748"/>
        <property type="gene ID" value="OSTLU_31063"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31063"/>
    <dbReference type="HOGENOM" id="CLU_2531562_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.50">
        <property type="entry name" value="Sep15/SelM thioredoxin-like domain, active-site redox motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038219">
        <property type="entry name" value="Sep15/SelM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014912">
        <property type="entry name" value="Sep15_SelM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08806">
        <property type="entry name" value="Sep15_SelM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Selenoprotein F/M" evidence="2">
        <location>
            <begin position="7"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="84" mass="9757" checksum="E983CD4AE8815A79" modified="2007-05-15" version="1">MRHRASRIKTFLKEVVEVGGYGERVGVTWTPGHPPSLHMQDERGNNVETAKLTSEWTVERVETYLNERGFYRPGQERETARVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVU7</accession>
    <name>A4RVU7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_3863</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417472.1">
        <property type="nucleotide sequence ID" value="XM_001417435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVU7"/>
    <dbReference type="SMR" id="A4RVU7"/>
    <dbReference type="STRING" id="436017.A4RVU7"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="5001596"/>
    <dbReference type="Gramene" id="ABO95765">
        <property type="protein sequence ID" value="ABO95765"/>
        <property type="gene ID" value="OSTLU_3863"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3863"/>
    <dbReference type="eggNOG" id="ENOG502QVVQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031603_0_0_1"/>
    <dbReference type="OMA" id="SDFIATN"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="10">
        <location>
            <begin position="3"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="39797" checksum="579BB77315E23511" modified="2007-05-15" version="1" fragment="single">KDAFVRVNGNKFELGGKEFIFAGWNQWEMMEAATGAGPPARHLPLPGREHIQRLLNEGVAEGLKVVRVWAHTISKGNEVQSRPGVWDEDALRGLDFFLDEARKRDVKVCLVLADNWYPVGGVDQYVAWSQTADKHQDFFTDSNSKRIFKDMIKTITTRRNTINGVRYGDDATIMSYNLVNEARCQNCPASTIGKWIDEMATYLKSFAPNQLVGLGYEGFFHSDDPAERQATNPGEGSDWASREGQSWARHSRMDSIDYVSIHVWPDNWFPTQSVELQQKFIKSRINIAERIGKPFVLEEFGKKVDRNEGATGFAERDKYFAAAFDLAESAARDGKLSGTIFWHWYDRGVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVV5</accession>
    <name>A4RVV5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Possible early light induced protein or carotenoid biosynthesis related, also has beta-Ig-H3/fasciclin domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ELIP4</name>
        <name evidence="5" type="ORF">OSTLU_14984</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417214.1">
        <property type="nucleotide sequence ID" value="XM_001417177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVV5"/>
    <dbReference type="GeneID" id="5001599"/>
    <dbReference type="Gramene" id="ABO95507">
        <property type="protein sequence ID" value="ABO95507"/>
        <property type="gene ID" value="OSTLU_14984"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14984"/>
    <dbReference type="eggNOG" id="KOG1437">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_872622_0_0_1"/>
    <dbReference type="OMA" id="EANPFKM"/>
    <dbReference type="OrthoDB" id="513190at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.180.10:FF:000032">
        <property type="entry name" value="Fasciclin domain-containing protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="4">
        <location>
            <begin position="41"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="34168" checksum="CB70575D07BC6626" modified="2007-05-15" version="1">MAMLATSRAYALAHARPRLASPYRHRASSSHRAVAVESTSTTASDLGALGDGRFSKLLGALDVAELTSVIAGSDEALTVFAPTDEAFERCARDRALAFEELAERENLDEILKYHVVSGAVKSSDLKSGQVKTLNGRSVKVDVAGGEVKVDGVKVTEADKAAFGGNVVVHVVDEVVFPAFSINAKVQTPQEILAFEGWAPEVINGRVAMLGFVLALTGEIATGESFTTQAANNFGELTRTMFVWSLASLFPAFSSNEGYEANPFKMADSKEWEFVFRGCPPWLAVKDVFSPEVEQLNGRAAMIGCASMIVLETLLGHALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWP1</accession>
    <name>A4RWP1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_31405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417613.1">
        <property type="nucleotide sequence ID" value="XM_001417576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWP1"/>
    <dbReference type="GeneID" id="5001554"/>
    <dbReference type="Gramene" id="ABO95906">
        <property type="protein sequence ID" value="ABO95906"/>
        <property type="gene ID" value="OSTLU_31405"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31405"/>
    <dbReference type="HOGENOM" id="CLU_1771178_0_0_1"/>
    <dbReference type="OrthoDB" id="497226at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16458" checksum="5E3568FBB7B91BE0" modified="2007-05-15" version="1">MLALLRNHRRGLKADVLLNKVKGNMELDGYKSVLVGVGRMEQWDLAREIVEFVKAGGRERGDEVLTSNWFVALATRRLEEKAYDATCDVFGYMKEFGSVPSGETIETFAKLTVSGLFAQTFFCPRLRPSVVDDYTPSKTPSFGSESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWT4</accession>
    <name>A4RWT4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_37273</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417388.1">
        <property type="nucleotide sequence ID" value="XM_001417351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWT4"/>
    <dbReference type="STRING" id="436017.A4RWT4"/>
    <dbReference type="GeneID" id="5001653"/>
    <dbReference type="Gramene" id="ABO95681">
        <property type="protein sequence ID" value="ABO95681"/>
        <property type="gene ID" value="OSTLU_37273"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37273"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_1"/>
    <dbReference type="OrthoDB" id="3633556at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF5">
        <property type="entry name" value="MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="172"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="579"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="674" mass="72809" checksum="F883FB81527A82D4" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX62</accession>
    <name>A4RX62_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417940.1">
        <property type="nucleotide sequence ID" value="XM_001417903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX62"/>
    <dbReference type="GeneID" id="5001984"/>
    <dbReference type="Gramene" id="ABO96233">
        <property type="protein sequence ID" value="ABO96233"/>
        <property type="gene ID" value="OSTLU_31580"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31580"/>
    <dbReference type="eggNOG" id="ENOG502S9R4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1985326_0_0_1"/>
    <dbReference type="OrthoDB" id="497979at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="126" mass="13927" checksum="31E3D874821F25F8" modified="2007-05-15" version="1">MRAVTNTVAPARVARASARANVARRSRRAIAVSPRANAAQVVAQTAIDLNEETVTAIGAAVLGLGAGLGIPIFFVWQERRDKERLEEIRELNRATLKATGEQMSPEEIAELRPSRYLDRREFKDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXI5</accession>
    <name>A4RXI5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_38674</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418004.1">
        <property type="nucleotide sequence ID" value="XM_001417967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXI5"/>
    <dbReference type="STRING" id="436017.A4RXI5"/>
    <dbReference type="GeneID" id="5001799"/>
    <dbReference type="Gramene" id="ABO96297">
        <property type="protein sequence ID" value="ABO96297"/>
        <property type="gene ID" value="OSTLU_38674"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38674"/>
    <dbReference type="eggNOG" id="KOG0667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_5_15_1"/>
    <dbReference type="OMA" id="ILLYHNG"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="71"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="397" mass="45682" checksum="7483D58CF1DED047" modified="2007-05-15" version="1">MSIVEAMQKFWKRLRVMDRNDILRYKHVWYVPTLEHLSDDTQTLSHGSGASSGDEDDAFRIRKGEHVAFRFEMFNSLGAGNFGQVVRCFDHKYKREVALKLISPDETFASQARVEVSVLKRVEGGSSRVVKMFEHLKFRGRLCVVFELLHINLYEFLEARAFAKLDIQHVRHIARQMVDALVYLKHMQVVHCDIKPENILLEHPGSFDVKLIDFGSACFQGKQVYTYIQSRFYRAPEVMLGIDYGHPIDVWSLACVLAELATGKTLFVGDDEARQLSAITSRIGPPPRRILSSAAHSDRRVDFHVCESSFARSRRDDKRSDRTSSKHKPRSKRTKVIDIDDDRFNAFLLRALHWNPSRRLTPDAARRHSFLQKRQAVVGEAAVDDAVRTGRELQTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXP5</accession>
    <name>A4RXP5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_38572</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417794.1">
        <property type="nucleotide sequence ID" value="XM_001417757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXP5"/>
    <dbReference type="STRING" id="436017.A4RXP5"/>
    <dbReference type="GeneID" id="5002107"/>
    <dbReference type="Gramene" id="ABO96087">
        <property type="protein sequence ID" value="ABO96087"/>
        <property type="gene ID" value="OSTLU_38572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38572"/>
    <dbReference type="eggNOG" id="KOG2078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022610_2_1_1"/>
    <dbReference type="OMA" id="VGSHSQF"/>
    <dbReference type="OrthoDB" id="408788at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF36">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="11">
        <location>
            <begin position="137"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="264"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="292"/>
            <end position="293"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="410" mass="45825" checksum="8D6F969790E3AC99" modified="2007-05-15" version="1">MVATALNGPLSPPPAVHVDREQFKTSLRVRAIRVPTRETDAVLKALRGFALDLPRVKAVTRDAEGERDGNLILLNDKVVDDDLRAVVPEERLSVVRERVGGEIEVTEYDVPLTYEYFNAAQVLRKLLPSAVEVPSSFETVGHIAHMNLRDEHESHKYLIGKVILEKNERLRTVVNKVGSIESEFRVPEWELLAGEPSLVTEVKQHGMTFKLDFGSVYWNSRLETEHKRLVDSFKANEVICDATSGVGPFSVPAAQKGIRCYASDLNPDCAKYLKINAKENRVKNLVKCYNMDARAFIKALLAAPENRATFDHLVTNLPASGIEFLDCLRGSFDRKVWEHRELPMIHCYTFKGADETDADVIKRGAGHLGAEIVDAAVSEVRDVSPNKLMVLLSFRISAEAAFCTKRQCTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXY1</accession>
    <name>A4RXY1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">30S ribosomal protein S9, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPS16</name>
        <name evidence="8" type="ORF">OSTLU_31856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417833.1">
        <property type="nucleotide sequence ID" value="XM_001417796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXY1"/>
    <dbReference type="STRING" id="436017.A4RXY1"/>
    <dbReference type="GeneID" id="5001961"/>
    <dbReference type="Gramene" id="ABO96126">
        <property type="protein sequence ID" value="ABO96126"/>
        <property type="gene ID" value="OSTLU_31856"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31856"/>
    <dbReference type="eggNOG" id="KOG1753">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046483_4_0_1"/>
    <dbReference type="OMA" id="WPIEMAR"/>
    <dbReference type="OrthoDB" id="186964at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000007">
        <property type="entry name" value="40S ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001749">
        <property type="entry name" value="PRK00474.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF16">
        <property type="entry name" value="RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="139" mass="15605" checksum="E0E23020DAC550FD" modified="2007-05-15" version="1">MSVQTFGRKKTAVAVAHTKRGKGLIRLNGVPIDLVQPDTLRLKAVEPILLLGKERFANVDIRIRVKGGGHVSQMYAVRQAIAKSLVAYYQKYVDEASKKEIKDLLLAYDRTLLVADPRRMEPKKAGGRGARARFQKSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXY8</accession>
    <name>A4RXY8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylenetetrahydrofolate reductase (NAD(P)H)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417836.1">
        <property type="nucleotide sequence ID" value="XM_001417799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXY8"/>
    <dbReference type="GeneID" id="5001789"/>
    <dbReference type="Gramene" id="ABO96129">
        <property type="protein sequence ID" value="ABO96129"/>
        <property type="gene ID" value="OSTLU_92796"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92796"/>
    <dbReference type="eggNOG" id="ENOG502S10R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1041548_0_0_1"/>
    <dbReference type="OMA" id="NIPCKGL"/>
    <dbReference type="OrthoDB" id="551422at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="32189" checksum="2256E685743BA6B3" modified="2007-05-15" version="1">MSTRIAPRYELFFKDVKCLETELRALRRRTSSATTRVNVPNKDKKDDLIAWIDAARTLSDDVDVVPHYSMKNQYRRDANQSVEAVKAFADAMTARNIDRCLLVSGSGSRKCDSVEVLRRLAMDREWKRRASTFRFDVAYNPHFDEGSDAAAREFERLEKKMRGGLVRGVWFQIGSDVEKLERGLERVRDLAPDAEIYGSVFLPSKQLLARMKFRPWAGVFLSDEYLSSVERAEEITIAQMACLVRHGATPFIESPVTKDEDWAQCERLLAAAAKRVDESGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXZ6</accession>
    <name>A4RXZ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_38697</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417841.1">
        <property type="nucleotide sequence ID" value="XM_001417804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXZ6"/>
    <dbReference type="STRING" id="436017.A4RXZ6"/>
    <dbReference type="GeneID" id="5001996"/>
    <dbReference type="Gramene" id="ABO96134">
        <property type="protein sequence ID" value="ABO96134"/>
        <property type="gene ID" value="OSTLU_38697"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38697"/>
    <dbReference type="eggNOG" id="KOG0922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_5_11_1"/>
    <dbReference type="OMA" id="FHEVMET"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000578">
        <property type="entry name" value="probable ATP-dependent RNA helicase DHX35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF136">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX35-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="63"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="263"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="713" mass="77693" checksum="45D8B764418EB953" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY23</accession>
    <name>A4RY23_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trehalase</fullName>
            <ecNumber evidence="4">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_38852</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="4"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418096.1">
        <property type="nucleotide sequence ID" value="XM_001418059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY23"/>
    <dbReference type="STRING" id="436017.A4RY23"/>
    <dbReference type="CAZy" id="GH37">
        <property type="family name" value="Glycoside Hydrolase Family 37"/>
    </dbReference>
    <dbReference type="GeneID" id="5002087"/>
    <dbReference type="Gramene" id="ABO96389">
        <property type="protein sequence ID" value="ABO96389"/>
        <property type="gene ID" value="OSTLU_38852"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38852"/>
    <dbReference type="eggNOG" id="KOG0602">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006451_4_0_1"/>
    <dbReference type="OMA" id="RYWDASD"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF1">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="593" mass="67403" checksum="220C1521F698AAFE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYD0</accession>
    <name>A4RYD0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418147.1">
        <property type="nucleotide sequence ID" value="XM_001418110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYD0"/>
    <dbReference type="GeneID" id="5002243"/>
    <dbReference type="Gramene" id="ABO96440">
        <property type="protein sequence ID" value="ABO96440"/>
        <property type="gene ID" value="OSTLU_15647"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15647"/>
    <dbReference type="HOGENOM" id="CLU_458136_0_0_1"/>
    <dbReference type="OMA" id="FDARTCE"/>
    <dbReference type="OrthoDB" id="10572414at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="596" mass="66442" checksum="62F18496FBCCFC73" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYN2</accession>
    <name>A4RYN2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418195.1">
        <property type="nucleotide sequence ID" value="XM_001418158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYN2"/>
    <dbReference type="STRING" id="436017.A4RYN2"/>
    <dbReference type="GeneID" id="5002174"/>
    <dbReference type="Gramene" id="ABO96488">
        <property type="protein sequence ID" value="ABO96488"/>
        <property type="gene ID" value="OSTLU_94479"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94479"/>
    <dbReference type="eggNOG" id="KOG1543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_843053_0_0_1"/>
    <dbReference type="OMA" id="WRNWGEN"/>
    <dbReference type="OrthoDB" id="190265at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="2">
        <location>
            <begin position="112"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="35390" checksum="F9711BFA45FFA136" modified="2007-05-15" version="1">MKRDESDDSVGFLGAYDGMMSGMLDQPRTFVKLVPEWATAGLGFEGGADSSDGAEAKKLSLFVADVFPLLHVNRRVPLSPHASSDETHGVHHFLTRLPALGKVELRAKDNRLPTSFDARVAYPKCSRLLGAVRDQGRCGSCWAVAATEVMNDRLCVATDGENADELSPQYALSCFDSGSGCDGGDVLDTLRIAFTKGIPYGGMLDSNACLPYEFEACDHPCMVAGTTPQSCPAKCADGSALSFVHPTSEPYTCPKGDVTHTGSGVYTVPNDAGEPLGQHATKLIGWGVSEEGEHYWWMVNSWRNWGENGVSKVRMGEMNIESGIAAIAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ38</accession>
    <name>A4RZ38_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_10487</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="8">The heme is bound between the two transmembrane subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418508.1">
        <property type="nucleotide sequence ID" value="XM_001418471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ38"/>
    <dbReference type="STRING" id="436017.A4RZ38"/>
    <dbReference type="GeneID" id="5002281"/>
    <dbReference type="Gramene" id="ABO96801">
        <property type="protein sequence ID" value="ABO96801"/>
        <property type="gene ID" value="OSTLU_10487"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10487"/>
    <dbReference type="eggNOG" id="ENOG502S9YU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243497_0_0_1"/>
    <dbReference type="OrthoDB" id="588261at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000178">
        <property type="entry name" value="SDH_cyt_b560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with second transmembrane subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000178-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="105" mass="10718" checksum="DAEC17BE23157C94" modified="2007-05-15" version="1" fragment="single">YKFPAVALSSITNRVTGVALTGAMSAGGIIALVGGAEAVPMTMEMFKANAPLAVVPVKFALSFPFVFHTLGGFRHLVWDSTTKGIDNESANASSLAIFGVSAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ99</accession>
    <name>A4RZ99_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418537.1">
        <property type="nucleotide sequence ID" value="XM_001418500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ99"/>
    <dbReference type="STRING" id="436017.A4RZ99"/>
    <dbReference type="GeneID" id="5002430"/>
    <dbReference type="Gramene" id="ABO96830">
        <property type="protein sequence ID" value="ABO96830"/>
        <property type="gene ID" value="OSTLU_32308"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32308"/>
    <dbReference type="eggNOG" id="KOG2134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1328298_0_0_1"/>
    <dbReference type="OMA" id="RRCRFQD"/>
    <dbReference type="OrthoDB" id="3512845at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="22925" checksum="7337F0770A6040EF" modified="2007-05-15" version="1">MFERAPRAPVVLVLVGPSGAGKSTFSARLPRERWTTANQDTVSNGKRGTRQQCVRVAKRALEEGKHVVIDRCGLSRQQRADFVALAREARPPCELRAVWFNQPVSVYQQRVRMRTNHPGGVQGESSVRVVQLQMRGKDNAPPTKEEGFRIVRRCRFQDDVDAACAAFCALPAAETAVEFPKKSKPERTLDSVREPSVVEDAVADAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZQ6</accession>
    <name>A4RZQ6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_12688</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Protein transport. Probably involved in vesicular traffic.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418612.1">
        <property type="nucleotide sequence ID" value="XM_001418575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZQ6"/>
    <dbReference type="STRING" id="436017.A4RZQ6"/>
    <dbReference type="GeneID" id="5002666"/>
    <dbReference type="Gramene" id="ABO96905">
        <property type="protein sequence ID" value="ABO96905"/>
        <property type="gene ID" value="OSTLU_12688"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12688"/>
    <dbReference type="eggNOG" id="KOG0098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_23_0_1"/>
    <dbReference type="OMA" id="WLQDCRA"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01866">
        <property type="entry name" value="Rab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000263">
        <property type="entry name" value="Ras-related protein RABB1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="212" mass="23081" checksum="A346C18F38342D85" modified="2007-05-15" version="1">MSYAYLFKYIVIGDTGVGKSCLLLQFTDKTFQPVHDLTIGVEFGSRMVSVASKQVKLQIWDTAGQESFRSITRSYYRGAAAALLVYDVTRRETFDNLSTWLQDCRAHANPNMVITLVGNKADISHRRAVSTEEGEMFARENGLLFVEASAKTADHVEDAFIATAREVVKNIDAGLDVKDESNGVKLGYVAGGGASDTVGLNAPPRVEQSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZQ8</accession>
    <name>A4RZQ8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_12689</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418839.1">
        <property type="nucleotide sequence ID" value="XM_001418802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZQ8"/>
    <dbReference type="STRING" id="436017.A4RZQ8"/>
    <dbReference type="GeneID" id="5002668"/>
    <dbReference type="Gramene" id="ABO97132">
        <property type="protein sequence ID" value="ABO97132"/>
        <property type="gene ID" value="OSTLU_12689"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12689"/>
    <dbReference type="eggNOG" id="KOG0084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_10_1_1"/>
    <dbReference type="OMA" id="PDYHYLF"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000359">
        <property type="entry name" value="Small GTP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="203" mass="22539" checksum="7E76EE5358B49889" modified="2007-05-15" version="1">MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTGTYISTIGVDFKIRTVELEGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDMESFEAVKGWLNEIDRYANENVNKLLVGNKSDLTSQKVVDYATAKAFADEIGIPFIETSAKNATNVEQAFMTMANEIKNRMASQPQMNAGPRGNTVRPGEGRSVNAKSSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZX1</accession>
    <name>A4RZX1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription elongation factor Eaf N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418874.1">
        <property type="nucleotide sequence ID" value="XM_001418837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZX1"/>
    <dbReference type="GeneID" id="5002960"/>
    <dbReference type="Gramene" id="ABO97167">
        <property type="protein sequence ID" value="ABO97167"/>
        <property type="gene ID" value="OSTLU_32542"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32542"/>
    <dbReference type="HOGENOM" id="CLU_2041966_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="12659" checksum="760688FC3E0FA0B9" modified="2007-05-15" version="1">MRRARRARGREDAEEGEAPRASDDGASEDVGIDCALVFDEASGTFTLEAVDGEIGNLRIAREDAEDVGAGELTTKTEERRAAAAAAAASAAARDAREGADANGERDVVDALPSSKKKPRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S014</accession>
    <name>A4S014_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADPH-protochlorophyllide oxidoreductase</fullName>
            <ecNumber evidence="7">1.3.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_4180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>chlorophyllide a + NADP(+) = protochlorophyllide a + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11132"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:83348"/>
            <dbReference type="ChEBI" id="CHEBI:83350"/>
            <dbReference type="EC" id="1.3.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.33" evidence="7"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418894.1">
        <property type="nucleotide sequence ID" value="XM_001418857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S014"/>
    <dbReference type="STRING" id="436017.A4S014"/>
    <dbReference type="GeneID" id="5002635"/>
    <dbReference type="Gramene" id="ABO97187">
        <property type="protein sequence ID" value="ABO97187"/>
        <property type="gene ID" value="OSTLU_4180"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4180"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_3_1"/>
    <dbReference type="OMA" id="WSWGNRQ"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="UniPathway" id="UPA00668"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016630">
        <property type="term" value="F:protochlorophyllide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005979">
        <property type="entry name" value="Prochl_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01289">
        <property type="entry name" value="LPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44419:SF19">
        <property type="entry name" value="PROTOCHLOROPHYLLIDE REDUCTASE A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44419">
        <property type="entry name" value="PROTOCHLOROPHYLLIDE REDUCTASE C, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="328" mass="36248" checksum="528C26197C4A6AE1" modified="2007-05-15" version="1" fragment="single">IVTGSSSGLGLYTAKALIKNGYFVVNAVRSPEKMQVKANELGLDESSYAIMYLELGDLQSVRDFATEFRRSKYVKNFQALVCNAALYLPNATVPSYTKDGFEECVGVNHLGHHLLSLLLLDDLAEAPDANMKRLIIVGSVTGNTNTLAGQVPPRAGLGDMSGLRNGFKNSDRNQGALIDGTRFIGAKAYKDSKLCNMLDIKAFAERFGESTGIKFSTMYPGCIADSNLFRNHTAFFRWFFPILQKNVTKGYVSEEEAGERLASIVYDPRYSEQGAYWAWKGGGDQLWDNYNNNNDDTRTIAFNNKPSKEGRDMAKANEVFDISTELVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S039</accession>
    <name>A4S039_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_6116</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418677.1">
        <property type="nucleotide sequence ID" value="XM_001418640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S039"/>
    <dbReference type="STRING" id="436017.A4S039"/>
    <dbReference type="GeneID" id="5002994"/>
    <dbReference type="Gramene" id="ABO96970">
        <property type="protein sequence ID" value="ABO96970"/>
        <property type="gene ID" value="OSTLU_6116"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6116"/>
    <dbReference type="eggNOG" id="KOG2381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059282_0_0_1"/>
    <dbReference type="OMA" id="RECMAYL"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044571">
        <property type="entry name" value="P4KG1-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45800">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45800:SF4">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE GAMMA 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="245" mass="26871" checksum="5548111B60798A4D" modified="2007-05-15" version="1" fragment="single">AVFKPADEEPFAPNNPRGHRSSHNGEGMRKGTKAGEGATREVAAYLLDHGGFAGVPATSLVNLTDGTEEDDGKLGSLQEYVENTAEAEEYGPSMFPTEEVHKITVLDIRLANTDRNAGNILCRSDENGNIVALIPIDHGYALPHTLEDVCFEWEFWPQASIPYSDDVKEYVAMLDADADVEYLRENDIELQASSERVLRVCTLVLKEAVRRNFTAANIASMLSRKMSNRKSDIEKIAAQAASTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0A6</accession>
    <name>A4S0A6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_93033</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418937.1">
        <property type="nucleotide sequence ID" value="XM_001418900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0A6"/>
    <dbReference type="STRING" id="436017.A4S0A6"/>
    <dbReference type="GeneID" id="5003031"/>
    <dbReference type="Gramene" id="ABO97230">
        <property type="protein sequence ID" value="ABO97230"/>
        <property type="gene ID" value="OSTLU_93033"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93033"/>
    <dbReference type="eggNOG" id="ENOG502S70Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1139359_0_0_1"/>
    <dbReference type="OMA" id="FERECHG"/>
    <dbReference type="OrthoDB" id="2017317at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="263" mass="27913" checksum="43D6994D486AE72D" modified="2007-05-15" version="1">MFATAAPAPRAAPAPRAARSTTPPSSARASARASSSGADVLYFCYGSNLNPSTFDGVRGMRPTSSTPCVLRGFELAFNVPGVPYVEPAFASAVAREGAECHGVAHGITRDEWEYLVTTEGSYDVVDVDCDAYDGRKLRCKTLTHRTLKNFGERAPSLRYATLLREGARFHGLDEAWIARLDALETYEPVELDLGQRAALALSVGPTLLAAVPAAGAAAAKRLSTGDGRGAVIDAFVETQDVVWGVQNAFFAPWMGSSGRNAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0C6</accession>
    <name>A4S0C6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_35485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418949.1">
        <property type="nucleotide sequence ID" value="XM_001418912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0C6"/>
    <dbReference type="GeneID" id="5003039"/>
    <dbReference type="Gramene" id="ABO97242">
        <property type="protein sequence ID" value="ABO97242"/>
        <property type="gene ID" value="OSTLU_35485"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35485"/>
    <dbReference type="eggNOG" id="KOG1296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114688_3_0_1"/>
    <dbReference type="OMA" id="GWFEYCE"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="163" mass="18119" checksum="86380C2D32E09576" modified="2007-05-15" version="1">MVLLVLYCKAEFENVASVEFPAGYHYCFDVKDSQSDETREGVFMSADDVVEMENSRGEANFVMKFPDSKKQASVSFVDVKGLTTKGVIDASGTWVPVMGFECRGLELEKFYPTKGATVKSEGGSTWRDVDLSEDPDGWFEYCENGGDSVGITEFTCEIRKHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0C9</accession>
    <name>A4S0C9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_32696</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418951.1">
        <property type="nucleotide sequence ID" value="XM_001418914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0C9"/>
    <dbReference type="STRING" id="436017.A4S0C9"/>
    <dbReference type="GeneID" id="5003040"/>
    <dbReference type="Gramene" id="ABO97244">
        <property type="protein sequence ID" value="ABO97244"/>
        <property type="gene ID" value="OSTLU_32696"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32696"/>
    <dbReference type="eggNOG" id="KOG2562">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019589_3_0_1"/>
    <dbReference type="OMA" id="NCISANV"/>
    <dbReference type="OrthoDB" id="5586at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21504">
        <property type="entry name" value="PPP2R3A_B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.220:FF:000003">
        <property type="entry name" value="Phosphoprotein phosphatase 2A regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000025">
        <property type="entry name" value="serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041534">
        <property type="entry name" value="EF-hand_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095:SF0">
        <property type="entry name" value="MIP22305P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095">
        <property type="entry name" value="PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17958">
        <property type="entry name" value="EF-hand_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="387"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="531" mass="61944" checksum="DBEE19D8628F68B6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0E3</accession>
    <name>A4S0E3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CW-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_87805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418957.1">
        <property type="nucleotide sequence ID" value="XM_001418920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0E3"/>
    <dbReference type="STRING" id="436017.A4S0E3"/>
    <dbReference type="GeneID" id="5002899"/>
    <dbReference type="Gramene" id="ABO97250">
        <property type="protein sequence ID" value="ABO97250"/>
        <property type="gene ID" value="OSTLU_87805"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87805"/>
    <dbReference type="eggNOG" id="ENOG502QPTV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_334437_0_0_1"/>
    <dbReference type="OMA" id="YRDSWIA"/>
    <dbReference type="OrthoDB" id="497506at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05162">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011124">
        <property type="entry name" value="Znf_CW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51050">
        <property type="entry name" value="ZF_CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CW-type" evidence="6">
        <location>
            <begin position="501"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="746"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="847" mass="94467" checksum="D4A108A6CF693B99" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="119" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0K0</accession>
    <name>A4S0K0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">p-ATPase family transporter: copper ion heavy metal transporting P-type ATPase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HMA2</name>
        <name evidence="12" type="ORF">OSTLU_611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418991.1">
        <property type="nucleotide sequence ID" value="XM_001418954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0K0"/>
    <dbReference type="STRING" id="436017.A4S0K0"/>
    <dbReference type="GeneID" id="5002831"/>
    <dbReference type="Gramene" id="ABO97284">
        <property type="protein sequence ID" value="ABO97284"/>
        <property type="gene ID" value="OSTLU_611"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_611"/>
    <dbReference type="eggNOG" id="KOG0207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_0_3_1"/>
    <dbReference type="OMA" id="LFYTGYP"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF19">
        <property type="entry name" value="COPPER-TRANSPORTING ATPASE PAA2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="4"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="776" mass="79910" checksum="9DAB707AF5C91CED" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S192</accession>
    <name>A4S192_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_42499</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419109.1">
        <property type="nucleotide sequence ID" value="XM_001419072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S192"/>
    <dbReference type="STRING" id="436017.A4S192"/>
    <dbReference type="GeneID" id="5003414"/>
    <dbReference type="Gramene" id="ABO97402">
        <property type="protein sequence ID" value="ABO97402"/>
        <property type="gene ID" value="OSTLU_42499"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42499"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_1"/>
    <dbReference type="OMA" id="FKMHRQP"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="45093" checksum="72B3FB2EDDB700EE" modified="2007-05-15" version="1">MQVNLKNYKKDTEFSYEPFLEILGTGLVTSEGETWREQRQRISSALRVEILDDIIAIATRAVDRLSEKLERVRGKNEPVELAEEFRLLTLQVIAEAILSLTPEQSDEVMPNLYLPIMEECNRRSLEPWRKYLPTPEWFAHRKRVAMLNEYIVNLIRGRWKKRTSGEANENPDILDRVLASVEVEDYGADIEEQMCYEIKTFLLAGHETSAAMLIWTTWELVNNEEKMAKAVAEANKVLGKVKPGRLPTRDELAHLDYNVSALKESLRLYSVVPVVTRRAIADDVLGGCRIPKGTTVIISLQGVHHREDLWPNPLSFEPERFLDGKNDELGNYAYLPFIQGPRNCLGQYLALLEARVVLATLIRRFKFKSASTKNGAKHTKAIPIAPADGMWFTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1D3</accession>
    <name>A4S1D3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein ENHANCED DISEASE RESISTANCE 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419130.1">
        <property type="nucleotide sequence ID" value="XM_001419093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1D3"/>
    <dbReference type="STRING" id="436017.A4S1D3"/>
    <dbReference type="GeneID" id="5003295"/>
    <dbReference type="Gramene" id="ABO97423">
        <property type="protein sequence ID" value="ABO97423"/>
        <property type="gene ID" value="OSTLU_16445"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16445"/>
    <dbReference type="eggNOG" id="ENOG502QQV7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_793191_0_0_1"/>
    <dbReference type="OMA" id="SCRINYA"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009769">
        <property type="entry name" value="EDR2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31558">
        <property type="entry name" value="CW14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31558:SF3">
        <property type="entry name" value="CW14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07059">
        <property type="entry name" value="EDR2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein ENHANCED DISEASE RESISTANCE 2 C-terminal" evidence="1">
        <location>
            <begin position="69"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="350" mass="38825" checksum="EB0822CE793388ED" modified="2007-05-15" version="1">MPSFMRAKSLTRLKSANDEKLARGGSLARWKSALGPVETQTTGDMAKCVVPVFEAGMETLADEAGDASWSENLSGEGFKLRGKTYKQDKKKTPSGEPFYNVKGVLSFKSDEKVGDWIKNLFADDLGKKIKGQVPSVIIVNIMVPDYKPTGGMFAKKENDGPGHNVVLLCKISDFARKTLEETEDWETLPADFKLLIRYVKGDGTGNVDTHPHELAVRQQTKMVVMVVAGNAALPWIVRQAVNHGNGKPFMVNRTSSYIERSGALEINVDAHNFSNVALNGLRTVHTSLGKLILDVGATVQGETEYELPERLLFSCRINYAKIERIVAHVDMLEAYPKDRAWLNDIRKRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1J0</accession>
    <name>A4S1J0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_16489</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419156.1">
        <property type="nucleotide sequence ID" value="XM_001419119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1J0"/>
    <dbReference type="STRING" id="436017.A4S1J0"/>
    <dbReference type="GeneID" id="5003214"/>
    <dbReference type="Gramene" id="ABO97449">
        <property type="protein sequence ID" value="ABO97449"/>
        <property type="gene ID" value="OSTLU_16489"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16489"/>
    <dbReference type="eggNOG" id="KOG0831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_783786_0_0_1"/>
    <dbReference type="OMA" id="DWVPFRE"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="350" mass="38621" checksum="0C88E54536AE6204" modified="2007-05-15" version="1">MGSNAQRGALWREHRAVEAATIAAMRARGVRDVPWSSAKRMLAVLCVSAIYTSWILSPVVSAVAVILIPSLRAYVGCYLFASYALGVRVPMNGLYKFFCGLECGEENGWELVVEDATAGEKEIDCSKRAYLFAAHPHGLFASGCVGNIVLSDAALRRFRARHVRFFINNLLISVFPIIKDVLSSLGFLPCTAKMMRRVLGRGETGMIVVGGVQEVVLTGNVDVEELYLKNCFGFVKVAIQVGTPLVPVYTFGESLATGPDWVPFREIRKRLSYKFVFPFRSLGIVHRWGFCFPRGKLTTVVGPPIEVKQNDRPSREEVAAVHAQYCKSLLALIERNKAAAGYPTQVTRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1N0</accession>
    <name>A4S1N0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419178.1">
        <property type="nucleotide sequence ID" value="XM_001419141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1N0"/>
    <dbReference type="GeneID" id="5003232"/>
    <dbReference type="Gramene" id="ABO97471">
        <property type="protein sequence ID" value="ABO97471"/>
        <property type="gene ID" value="OSTLU_16519"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16519"/>
    <dbReference type="HOGENOM" id="CLU_840425_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="331" mass="36291" checksum="EA8B66303FEE49C9" modified="2007-05-15" version="1">MGARASANAARADAATLVEALALTRRELAEASAARATDAAATTAARETLRRELEAAREGRATEGELADARAALDDAREAARGATIETERLARECEEKRRELRALEREIERAAAVVKDNLARELARARSARDAPSKVVAVAEKTAQKAEIEAEARLAFERAAEARFRAELEAERARYESNLDELRSKLANAATAKDDAESEAASLRRRCDALDERLARDRMALLDATSALETRGQLIATLRRRIESLEARESEARMELKLHAKKDRKVKFDGIRQHEFGAPVARVEATAVAKSNVEATAVAKSNVDEQTPQSSSTRRAALQEIRRELADLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S202</accession>
    <name>A4S202_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419239.1">
        <property type="nucleotide sequence ID" value="XM_001419202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S202"/>
    <dbReference type="GeneID" id="5003500"/>
    <dbReference type="Gramene" id="ABO97532">
        <property type="protein sequence ID" value="ABO97532"/>
        <property type="gene ID" value="OSTLU_33277"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33277"/>
    <dbReference type="HOGENOM" id="CLU_1186668_0_0_1"/>
    <dbReference type="OMA" id="AFAMISE"/>
    <dbReference type="OrthoDB" id="10510342at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="234" mass="24984" checksum="695CF127AF849193" modified="2007-05-15" version="1">MGCSKCRYSDRGCARCVRDFVSNSAARTEGKLGIASKANANSNASNAKTGEKRRKSASQATSAVKRHKTSPVLKSGKSRNSLGAKTPAVKTPKARSGTTGTAPSRARATKTREGGESRIDEEDEYESDKENVRTAMDGGKWGARSVDSGGRVLFDECEAPSPKPIEEMSPGQLEMIVAKSPSSMRLGNGFDNDAPQSPLAAAFAMISEFLESPKRERQHRSGANVESFWGLAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S259</accession>
    <name>A4S259_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419691.1">
        <property type="nucleotide sequence ID" value="XM_001419654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S259"/>
    <dbReference type="GeneID" id="5003628"/>
    <dbReference type="Gramene" id="ABO97984">
        <property type="protein sequence ID" value="ABO97984"/>
        <property type="gene ID" value="OSTLU_25000"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25000"/>
    <dbReference type="HOGENOM" id="CLU_508453_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="536" mass="59289" checksum="C154F05F95674F5F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2B7</accession>
    <name>A4S2B7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_35082</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex with RFC1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419724.1">
        <property type="nucleotide sequence ID" value="XM_001419687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2B7"/>
    <dbReference type="STRING" id="436017.A4S2B7"/>
    <dbReference type="GeneID" id="5003537"/>
    <dbReference type="Gramene" id="ABO98017">
        <property type="protein sequence ID" value="ABO98017"/>
        <property type="gene ID" value="OSTLU_35082"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35082"/>
    <dbReference type="eggNOG" id="KOG0989">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_1_0_1"/>
    <dbReference type="OMA" id="GCQSGSF"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000129">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF20">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="48"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37532" checksum="87DE1668728F0425" modified="2007-05-15" version="1">MVDAEATRPQRAEAHAPWVEKYRPRVVKDVASQEQIVGVLENALKTGNMPHCLFYGPPGTGKTTTALAIAKELYGPELYKQRVKELNASDERGISVVRNKIKTFASQAVGAPAPGYPSPPYKILILDEADAMTGDAQSALRRMMETYSKVTRFFLLCNYVTKIIDPIASRCAKFRFSPLAQETMGARLKFIGEQEGLEMSDDVFAMCSKHSGGDMRKAITLLQSAARLFAGKISGASIVEVAGHIPDEKIKKMYDLCREGKFEEAQAHMEDILRDGFSGLKILDQYSDYVLEADCSDEVKAEIFIKLGEVDRFLAQGADEGMQLATLVSTSIKALAKMASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2N7</accession>
    <name>A4S2N7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">adenylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_88233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419781.1">
        <property type="nucleotide sequence ID" value="XM_001419744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2N7"/>
    <dbReference type="STRING" id="436017.A4S2N7"/>
    <dbReference type="GeneID" id="5003771"/>
    <dbReference type="Gramene" id="ABO98074">
        <property type="protein sequence ID" value="ABO98074"/>
        <property type="gene ID" value="OSTLU_88233"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88233"/>
    <dbReference type="eggNOG" id="KOG3078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032354_2_1_1"/>
    <dbReference type="OMA" id="FFKNSNC"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="30434" checksum="F503F1000FCAE892" modified="2007-05-15" version="1">MFARRLSVVTARALSRKYASTPFDATGAAVDALRDELASTCDGVLEQGKKLNWVFLGAPGVGKGTYASRMAKQMGVPHISMGDLVRAEIKGETALGKEMKAIAARGELVPDALVLDILDKRVKRGEAEGERGFLLDGFPRTVPQAETLSTMVEVTQVLNLTLREDILVEKCCGRRECGECGKSFNIADIRSEKAGEQTIIMPPLNPPQECFAKLTQRPDDTEEVVRARLEVYKKSTIPVENYYRGKGLLSDFPIMGGIPETTPVLLKHIIDILKASTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-04-02" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Z4</accession>
    <name>A4S2Z4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_16868</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419622.1">
        <property type="nucleotide sequence ID" value="XM_001419585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Z4"/>
    <dbReference type="STRING" id="436017.A4S2Z4"/>
    <dbReference type="GeneID" id="5003833"/>
    <dbReference type="KEGG" id="olu:OSTLU_16868"/>
    <dbReference type="HOGENOM" id="CLU_2230074_0_0_1"/>
    <dbReference type="OMA" id="DVFYNKP"/>
    <dbReference type="OrthoDB" id="1728669at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016423">
        <property type="term" value="F:tRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11916" checksum="3D5B9153D9BC193E" modified="2007-05-15" version="1" fragment="single">MGDGGADPKAPEGFEVIREGWARALQRAGGDDVFYNKPQVVNRDLSLAVIREFQKVRATEHANGQSKRNKRAKGAMCLTPRDDALLPRLLDEDDRAALFRSAEEHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S300</accession>
    <name>A4S300_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_16873</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419626.1">
        <property type="nucleotide sequence ID" value="XM_001419589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S300"/>
    <dbReference type="STRING" id="436017.A4S300"/>
    <dbReference type="GeneID" id="5003893"/>
    <dbReference type="Gramene" id="ABO97919">
        <property type="protein sequence ID" value="ABO97919"/>
        <property type="gene ID" value="OSTLU_16873"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16873"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_0_1"/>
    <dbReference type="OMA" id="IIYGQSE"/>
    <dbReference type="OrthoDB" id="10250117at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="8">
        <location>
            <begin position="6"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="405" mass="42602" checksum="AA0DC243CADE8741" modified="2007-05-15" version="1">MAHRCVYLDYNATTPIWPEVSRAMAPFLHEHFGNPSSGHAFATPCREAIDAARESTGAMLGCASDEVTFTSCGSESDNFAIDGAVRGFLKKNAGRGLPKIVTTAIEHPAVIEHLKAKAAFGELTYELVGVDEEGLVNADDVIDAIDENTCLVTVMHANNETGAIQPVAEIARRARERGVLTHTDAAQSAGKVPVKVDALGVDMATIVGHKIGAPKGVGALYIRRGTDLGDAKPFYGGGQESGRRAGTENVLHIVGLGKACEIVEREMDTCPKHLKAMRDDLQKRLVDALGGTDGSGVRVNGPRDDDKRLPNTLNIGIKGLLASITLMELSELLAASAGAACHTPDAATSGGATVSSVLEAMNVPMEYAVGTLRLSVGRHTVERDVERGAALLIDAAKRQNAGAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="113" xmlns="https://uniprot.org/uniprot">
    <accession>A4S339</accession>
    <name>A4S339_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="3 11">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_94760</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="3 11"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419851.1">
        <property type="nucleotide sequence ID" value="XM_001419814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S339"/>
    <dbReference type="STRING" id="436017.A4S339"/>
    <dbReference type="GeneID" id="5003517"/>
    <dbReference type="Gramene" id="ABO98144">
        <property type="protein sequence ID" value="ABO98144"/>
        <property type="gene ID" value="OSTLU_94760"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94760"/>
    <dbReference type="eggNOG" id="KOG0660">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OMA" id="VVCTAEY"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07858">
        <property type="entry name" value="STKc_TEY_MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000046">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008352">
        <property type="entry name" value="MAPK_HOG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01773">
        <property type="entry name" value="P38MAPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="41"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO98144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="405" mass="45634" checksum="860BABDB7CB7F2FF" modified="2007-05-15" version="1">MTSAKRRKARREREGRSGRGTAAVTSKFAVCGTVFEVDAKYAPIKPIGKGAYGVVCSARELETNRKVAIKKIVNAFENVVDAKRTLREIKLLRHLRHENVIDIIDCVKPRAKDAFEDVYLMYDLMDTDLYQIIRSSQSLTDEHCQYFVYQILRGLKYIHSADVLHRDLKPGNLLLNANCDLKICDFGLARTALVDAEASEFMTEYVVTRWYRAPELLLSCAEYTSAIDVWSVGCIFAELLGRKTLFPGKDYVHQLNLIMRVIGTPQNPSELDFINNEKAKRYIKSLPVTARCSFQKLFPNASPKAVDLVDKMLVLDPARRITVEEALAHPYLESLHDEVDEPCAESPFTFDFEDGAQYLTDTDVRGLIYDELCALSAEFEAAKLAQLSLGGDGQDEGNELSELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3U5</accession>
    <name>A4S3U5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ICln family transporter: chloride ion current inducer protein I(Cln)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_93353</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419982.1">
        <property type="nucleotide sequence ID" value="XM_001419945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3U5"/>
    <dbReference type="STRING" id="436017.A4S3U5"/>
    <dbReference type="GeneID" id="5004021"/>
    <dbReference type="Gramene" id="ABO98275">
        <property type="protein sequence ID" value="ABO98275"/>
        <property type="gene ID" value="OSTLU_93353"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93353"/>
    <dbReference type="eggNOG" id="KOG3238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1121639_0_0_1"/>
    <dbReference type="OMA" id="TSAYACE"/>
    <dbReference type="OrthoDB" id="19714at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="248" mass="27406" checksum="FAA17E5EE0FD7B8C" modified="2007-05-15" version="1">MYHRIVATARDVRVAASVDVVDAAHRDSRDMFRAPPEGLRARANALDDRRALRLHDDERCVLSCDAAMTIGDDDPASSAIPGELYITDARVAFVPRDPTSTSAYACEYRCLALHAISREDDRYGSGGCVYCQIDGGADAPSASTTTNADDANDDEPYDEDDPVTAHVRFVPKDATTLEEIYRAMSEGSLLNPDPDAERFDDDDDDDEFLEDDDEAHAREAALERLDKLLVVDDEVEALMKRDPGRFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Z9</accession>
    <name>A4S3Z9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420180.1">
        <property type="nucleotide sequence ID" value="XM_001420143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Z9"/>
    <dbReference type="GeneID" id="5004100"/>
    <dbReference type="Gramene" id="ABO98473">
        <property type="protein sequence ID" value="ABO98473"/>
        <property type="gene ID" value="OSTLU_26229"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26229"/>
    <dbReference type="HOGENOM" id="CLU_2376649_0_0_1"/>
    <dbReference type="OrthoDB" id="10453076at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="95" mass="10086" checksum="CF6E9D6AD10EB556" modified="2007-05-15" version="1">MVPPDASKPAPGWLQPLIGLAEPAGESATIVGYSLAIVTALLVTIVLAVLHFPGLFDVMVFFGTSAYACWQLGPYLDKIVADVEAQYNDKYGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="114" xmlns="https://uniprot.org/uniprot">
    <accession>A4S451</accession>
    <name>A4S451_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">p-ATPase family transporter: zinc/lead/cadmium/mercury ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_1206</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420208.1">
        <property type="nucleotide sequence ID" value="XM_001420171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S451"/>
    <dbReference type="STRING" id="436017.A4S451"/>
    <dbReference type="GeneID" id="5003933"/>
    <dbReference type="Gramene" id="ABO98501">
        <property type="protein sequence ID" value="ABO98501"/>
        <property type="gene ID" value="OSTLU_1206"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1206"/>
    <dbReference type="eggNOG" id="KOG0207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_6_4_1"/>
    <dbReference type="OMA" id="SFDEWIY"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051014">
        <property type="entry name" value="Cation_Transport_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48085">
        <property type="entry name" value="CADMIUM/ZINC-TRANSPORTING ATPASE HMA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48085:SF5">
        <property type="entry name" value="CADMIUM_ZINC-TRANSPORTING ATPASE HMA4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="223"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="9">
        <location>
            <begin position="83"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="617" mass="64763" checksum="61AD451759660745" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4S4</accession>
    <name>A4S4S4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MC family transporter: folate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_44261</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420486.1">
        <property type="nucleotide sequence ID" value="XM_001420449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4S4"/>
    <dbReference type="STRING" id="436017.A4S4S4"/>
    <dbReference type="GeneID" id="5004373"/>
    <dbReference type="Gramene" id="ABO98779">
        <property type="protein sequence ID" value="ABO98779"/>
        <property type="gene ID" value="OSTLU_44261"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44261"/>
    <dbReference type="eggNOG" id="KOG0757">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_6_4_1"/>
    <dbReference type="OMA" id="AFYNGMG"/>
    <dbReference type="OrthoDB" id="10266426at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015215">
        <property type="term" value="F:nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000075">
        <property type="entry name" value="Nicotinamide adenine dinucleotide transporter 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044712">
        <property type="entry name" value="SLC25A32-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45683">
        <property type="entry name" value="MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="48"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="142"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="248"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="345" mass="36991" checksum="A2353CEEAC6DC652" modified="2007-05-15" version="1">MTRRDAANARASTSSPDVDAFANPQHATNFYRNLARGAPPSALALLSDKAFANGFSGAIAGTVAATVVCPLDVLKTRLQVSAATTGTTEYLSTYGALRRIVRHEGARGLYRGLGPTVAALLPNWGVYFSTYGALKRIFIADANHFAHILAAAGAGAATIFVTNPLWVAKTRLQVQHSHALASAMPKRVPYTSTINALTRMMREEGLKGLYSGFGPSLIGIAHVIIQFPLYESIKVELAREREVAVNKIEPIDLMVASAIAKMIASTLTYPHEVIRSHMHVHGLGPFSGIGALVRRIYLEGGVAAFYRGCATNLIRTTPAAAITFTSFELVSREIEKLVAAAREDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4V3</accession>
    <name>A4S4V3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_2583</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420331.1">
        <property type="nucleotide sequence ID" value="XM_001420294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4V3"/>
    <dbReference type="STRING" id="436017.A4S4V3"/>
    <dbReference type="CAZy" id="GH1">
        <property type="family name" value="Glycoside Hydrolase Family 1"/>
    </dbReference>
    <dbReference type="GeneID" id="5004510"/>
    <dbReference type="Gramene" id="ABO98624">
        <property type="protein sequence ID" value="ABO98624"/>
        <property type="gene ID" value="OSTLU_2583"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2583"/>
    <dbReference type="eggNOG" id="KOG0626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001859_1_3_1"/>
    <dbReference type="OMA" id="MEPFAYA"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="51197" checksum="D0BF11CF18C8C7FD" modified="2007-05-15" version="1" fragment="single">FPPSFAFGVGTSAWQIEGNGGDRPRSVWDAFVSELGEEKRVEAERGIGFHERYAADAQMMADAGVKHFKMSLSWPRLMRADGSAIDEGFEYYQNVFGALRERGVEPHVTLFHWDTPIVCEGAWVKDEILKDFEKYADAVFSRLGKGIKYWTTISEPKTVAEMGYGAGLHAPGRRSVEEQLKVGHNMLRAHALAVALYREKYSQFGGKLSINLNSAWVEPASDSPDDVRAAANAMDEELGWFADPIYKGDYPASMRARLGSFLPEFTEEERVLVKGSVDYFALNHYTSYFAKHVTDAQASSQLGLSGRPQPWEITLESEKSKKPIGKEAQSDWLHIVPWGLEKVLLHIKDRYDDPAIMISENGVDIAERGDIAETLDDTTRVKFIDAYLGAAREAMRKGANVVGYFYWSMFDNVEWVDGRSKRFGLVYVDYDGKYGEKMKRYPKKSLEHFSSYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Y8</accession>
    <name>A4S4Y8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Lariat debranching enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_25255</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lariat debranching enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420516.1">
        <property type="nucleotide sequence ID" value="XM_001420479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Y8"/>
    <dbReference type="STRING" id="436017.A4S4Y8"/>
    <dbReference type="GeneID" id="5004531"/>
    <dbReference type="Gramene" id="ABO98809">
        <property type="protein sequence ID" value="ABO98809"/>
        <property type="gene ID" value="OSTLU_25255"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25255"/>
    <dbReference type="eggNOG" id="KOG2863">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005893_1_0_1"/>
    <dbReference type="OMA" id="TDYGDWK"/>
    <dbReference type="OrthoDB" id="494375at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00844">
        <property type="entry name" value="MPP_Dbr1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000035">
        <property type="entry name" value="Lariat debranching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041816">
        <property type="entry name" value="Dbr1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01124">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="14">
        <location>
            <begin position="235"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="387" mass="44035" checksum="3B7C1C97AD752E9E" modified="2007-05-15" version="1">MKIAIEGCCHGELDAIYAAIAHLEVVEKVKIDLLICCGDFQAVRNLDDLECMSVPDKYKELGTFYKYYSGEKTAPIPTLFIGGNHEASNYLWELYYGGYVAPNIYYVGHSGVVNFGDLRIGGLSGIFKTHDYKKGHHERPPYSGHAVKTAYHVREFDVFKLKQVKSEIDVFLSHDWPRGIAQFGNKHELFRKKKFLKDEIESNTLGSPPAEELLKRLKPKYWFSAHLHVKYAALVKHEDEKTTKFLALDKCLPHRDFLQVIDLPEKSAEGGFALDEEWLAILKANHEYHSVTHRPAQLPAYGTPEAIDLEPHKKWVSERLQAAGSSATVPPEFVATRPAYDPSSETRRKGRAPADVDVNPQTKALMDLLELDLKITTPRMHHTRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S597</accession>
    <name>A4S597_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDP-D-glucose phosphorylase 1</fullName>
            <ecNumber evidence="5">2.7.7.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_3702</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:30387"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:62230"/>
            <dbReference type="EC" id="2.7.7.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GDPGP1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.78" evidence="5"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420569.1">
        <property type="nucleotide sequence ID" value="XM_001420532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S597"/>
    <dbReference type="STRING" id="436017.A4S597"/>
    <dbReference type="GeneID" id="5004799"/>
    <dbReference type="Gramene" id="ABO98862">
        <property type="protein sequence ID" value="ABO98862"/>
        <property type="gene ID" value="OSTLU_3702"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3702"/>
    <dbReference type="eggNOG" id="KOG2720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041964_1_0_1"/>
    <dbReference type="OMA" id="GIQWPRT"/>
    <dbReference type="OrthoDB" id="417175at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080048">
        <property type="term" value="F:GDP-D-glucose phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026506">
        <property type="entry name" value="GDPGP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058865">
        <property type="entry name" value="GDPGP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058866">
        <property type="entry name" value="GDPGP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20884">
        <property type="entry name" value="GDP-D-GLUCOSE PHOSPHORYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20884:SF8">
        <property type="entry name" value="GDP-D-GLUCOSE PHOSPHORYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26216">
        <property type="entry name" value="GDPGP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26217">
        <property type="entry name" value="GDPGP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GDPGP1-like N-terminal" evidence="14">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="GDPGP1-like C-terminal" evidence="13">
        <location>
            <begin position="183"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF26216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF26217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="35470" checksum="4E98201A433D9EF2" modified="2007-05-15" version="1" fragment="single">DRILISAWEDRFAGGLFRYDVTAVSTKVIDGKKKYVAQFNIGRATNKRPTEFSVDKVCQDFDANKFNFTKADLKEVLFSFTKLAGEADENVSRSVFEPSAAVGESPTVVLINVSPIEYGHVLLCPRVTDMLPQQISPENLLPALYMAAESRNPYFRVGYNSLGAYATINHLHFQAYYLMEAFPIERANTVEIFPGTHGDCTVYRVNGYPVRCLCFEVGDSFEELASLVGGCAVKLQGANIPFNILIADHGARVFLIPQVFSIRIANNKIPEHVIHTGVNPAVFEISGHLLYKQESDYDQCTETSAEELLACASLTEEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5B2</accession>
    <name>A4S5B2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_17503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420743.1">
        <property type="nucleotide sequence ID" value="XM_001420706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5B2"/>
    <dbReference type="STRING" id="436017.A4S5B2"/>
    <dbReference type="GeneID" id="5004842"/>
    <dbReference type="Gramene" id="ABO99036">
        <property type="protein sequence ID" value="ABO99036"/>
        <property type="gene ID" value="OSTLU_17503"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17503"/>
    <dbReference type="HOGENOM" id="CLU_817332_0_0_1"/>
    <dbReference type="OMA" id="KAQRVSW"/>
    <dbReference type="OrthoDB" id="10516512at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36074">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36074:SF1">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="37026" checksum="7C5B68CAC28A0F18" modified="2007-05-15" version="1">MGVVNVARDAINASATLLTPTRARCDAQAAFPVRLSPSDGALVTHKMDAWDALRALARESRLAVVASEVQCSFLTDAYPDEALKEYAIERKTIGSTLTASACAWRAVRCAVVAFQRPVQEWLNEVDARITKETETGEPSELPEFDYIEPTRAAWWAFKRDSVVAATRRILEYLVVGRSSKRLSAKLCKDIRYSARRKAQRVSWERGLGKFAQAGNMFRTVTLANAINVSGEFVVDVTLASYEARWLRRRSSKASSRAISRAWRRALLRAACKAGSVLVGGAAACAAFTFCRPRGAGPRVVSWGTYASLTAGELAGGIFIAPTVFALVADANVEEPPPAIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5N0</accession>
    <name>A4S5N0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_17590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420637.1">
        <property type="nucleotide sequence ID" value="XM_001420600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5N0"/>
    <dbReference type="STRING" id="436017.A4S5N0"/>
    <dbReference type="GeneID" id="5004667"/>
    <dbReference type="Gramene" id="ABO98930">
        <property type="protein sequence ID" value="ABO98930"/>
        <property type="gene ID" value="OSTLU_17590"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17590"/>
    <dbReference type="eggNOG" id="KOG2753">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_678612_0_0_1"/>
    <dbReference type="OMA" id="LATWRAN"/>
    <dbReference type="OrthoDB" id="10267031at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF2">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="304"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="406" mass="43482" checksum="440E66C37DD9A046" modified="2007-05-15" version="1">MPLVERASDGGASPALVAACETLGVLIHGETERRATERADEDDASEARETAKEGASDVEDGEAEKFARALSAKPRGEVLEALTGHAETLFGDGGDKEVSGVVAVMANLAGDDGGAMKRVMECVTASVSERVSLRVRCAIALYNDADAKDGETKLELFEKIAAYCVAAKQKQVLPMLVAHASEAKAWGGEVKTQRRVLKLCVDLLRELEGREEELFSCMIKYLATFENDSGAVAEAADIAKETARIFISSPTMFHGDFLALKGMQHLQSADANALKLLSTMLTGSVADYNALVKANGSIVSGLGLDADDCVAKMRMMALAALGKKGDASYSEIKEAMQCDDGEVEEWVVRAVGAGVVDAKMDQMKQRVVFTRCTDRVFTGAEWQELSSRITQWRGKIAALQKTLSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Q8</accession>
    <name>A4S5Q8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420814.1">
        <property type="nucleotide sequence ID" value="XM_001420777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Q8"/>
    <dbReference type="STRING" id="436017.A4S5Q8"/>
    <dbReference type="GeneID" id="5004770"/>
    <dbReference type="Gramene" id="ABO99107">
        <property type="protein sequence ID" value="ABO99107"/>
        <property type="gene ID" value="OSTLU_26849"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26849"/>
    <dbReference type="eggNOG" id="ENOG502RXW6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033263_1_0_1"/>
    <dbReference type="OMA" id="MTGNWGQ"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36459:SF1">
        <property type="entry name" value="FATTY ACID DESATURASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36459">
        <property type="entry name" value="ORF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="39"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="330" mass="36330" checksum="61C4491F29A5F3BF" modified="2007-05-15" version="1">MVRDARDLPLVYALINVASTVPAMAMTVVMSPPSHALGLAYAVTIYGLYWRRFVTAAHYSSHAPAFRGDGTAGTVLNNVASCALGPFFGMPCGLYAMRHELMHHDGDEGSKASGGRGRGMNSTATYARDGAFAFLRYWVRFGAWCFVELLVGAVKRKAYVDAMRCVLGLAATYGVYSYAAAMNATAAFWIFVVPYVAGSFAAAFGSWSQQIFVDPDKPQCHYRSSYCAINHPNNQLTFNDGYYTVHRVDADAHWSDLPEKFIESLDEFARNDGLIFDGVTRRRVGLAVLCGRLGWLADRYVNVGQPARTKEEIVAMLRQRLRPVGKNKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5V0</accession>
    <name>A4S5V0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">GTE3501</name>
        <name evidence="15" type="ORF">OSTLU_17648</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MORC ATPase protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="GeneID" id="5004694"/>
    <dbReference type="Gramene" id="ABO99126">
        <property type="protein sequence ID" value="ABO99126"/>
        <property type="gene ID" value="OSTLU_17648"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17648"/>
    <dbReference type="eggNOG" id="KOG1474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_320904_0_0_1"/>
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        <property type="component" value="Chromosome 12"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of defense response"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    </dbReference>
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        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
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    </dbReference>
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        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
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        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045261">
        <property type="entry name" value="MORC_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041006">
        <property type="entry name" value="Morc_S5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23336:SF76">
        <property type="entry name" value="MORC S5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23336">
        <property type="entry name" value="ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01429">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17942">
        <property type="entry name" value="Morc6_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="13">
        <location>
            <begin position="425"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="MBD" evidence="14">
        <location>
            <begin position="767"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="358"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="533"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="838"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="643"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="857"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="895"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO99126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="904" mass="101792" checksum="E1D9CB0A212EC784" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S668</accession>
    <name>A4S668_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentapeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_8430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S668"/>
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        <property type="protein sequence ID" value="ABO99332"/>
        <property type="gene ID" value="OSTLU_8430"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8430"/>
    <dbReference type="HOGENOM" id="CLU_2580944_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47485">
        <property type="entry name" value="THYLAKOID LUMENAL 17.4 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47485:SF1">
        <property type="entry name" value="THYLAKOID LUMENAL 17.4 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="8567" checksum="84FB22B2AA15914F" modified="2007-05-15" version="1" fragment="single">AVLTLTGCDYSGKQLRGKILSGVVMDGTNFENADASETEMSRTSARNSNLRGVNFASANAYEARFDGSDLRGANFANALLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S680</accession>
    <name>A4S680_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">VIC family transporter: inwardly rectifying potassium ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_41686</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421044.1">
        <property type="nucleotide sequence ID" value="XM_001421007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S680"/>
    <dbReference type="STRING" id="436017.A4S680"/>
    <dbReference type="GeneID" id="5005106"/>
    <dbReference type="Gramene" id="ABO99337">
        <property type="protein sequence ID" value="ABO99337"/>
        <property type="gene ID" value="OSTLU_41686"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41686"/>
    <dbReference type="eggNOG" id="KOG0498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_369840_0_0_1"/>
    <dbReference type="OMA" id="ASHWSAC"/>
    <dbReference type="OrthoDB" id="2012993at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000123">
        <property type="entry name" value="Potassium channel KAT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
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    </dbReference>
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        <property type="entry name" value="POTASSIUM CHANNEL AKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
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        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="cAMP-binding domain-like"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="14">
        <location>
            <begin position="284"/>
            <end position="407"/>
        </location>
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            <begin position="477"/>
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        </location>
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        </location>
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        </location>
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        <location>
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            <end position="606"/>
        </location>
    </feature>
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        <location>
            <begin position="629"/>
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        </location>
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        <location>
            <begin position="635"/>
            <end position="648"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99337.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="648" mass="72495" checksum="BD346EABB0335C1A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S745</accession>
    <name>A4S745_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="OSTLU_93665"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="497695at2759"/>
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        <property type="component" value="Chromosome 14"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="304"/>
            <end position="372"/>
        </location>
    </feature>
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        <location>
            <begin position="304"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="42074" checksum="4145F095EDC28736" modified="2007-05-15" version="1">MSAPERRTDVFDGVLIPPASTSTAACGYKYYQDRNRKWPFHTNAQGAALLGQLFDDARRVIAALDAAIATLAPDDAAREAIVRSGVDIYAKKPSIRERDVTWSQTEYAHLGLQREYCRFKSVQRFTETWACLERARARGVFEDVGKGGDGETRRVASLGGGPGFELVAVREFFKAHFPSVTLDLVSLDLEESWRASAEALGLRFFQWDMRSGKVAETCGGAVDFALASYVYKMYMCEDDVADWFADELKDMHAAFIISRDQSLKTALMEKRGVDVRKLMALQTQRGDDRQLVFSRDRVFETWSTSTKSAHAPESSMTFPNVPYEEHKTGGGDQHRDRDRQRGFRGGWDRRDQAYVASRDADRVGKSRDSRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4S747</accession>
    <name>A4S747_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_18002</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421209.1">
        <property type="nucleotide sequence ID" value="XM_001421172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S747"/>
    <dbReference type="STRING" id="436017.A4S747"/>
    <dbReference type="GeneID" id="5005396"/>
    <dbReference type="Gramene" id="ABO99502">
        <property type="protein sequence ID" value="ABO99502"/>
        <property type="gene ID" value="OSTLU_18002"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18002"/>
    <dbReference type="eggNOG" id="KOG4163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_4_2_1"/>
    <dbReference type="OMA" id="HRWEMRT"/>
    <dbReference type="OrthoDB" id="1350766at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010109">
        <property type="term" value="P:regulation of photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000037">
        <property type="entry name" value="Proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000016">
        <property type="entry name" value="Proline--tRNA ligase, chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF3">
        <property type="entry name" value="PROLINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="448" mass="49931" checksum="7B757552AAAC8C31" modified="2007-05-15" version="1">MVIRPYGYAIWEGIQKYMDAKFKATGVQNAYFPQLIPYSFITKEASHVEGFAPELALVTRGGGKELEEPLVVRPTSETIVNNMLSQWIQSYRDLPMLLNQWCNVHRWEMRTRPFIRTLEFLWQEGHTAHATAEEAEERAMQMIRVYAEFAQTQAAMPVIPGRKSRVESFAGANVTYTIEAMMGDKKALQAGTSHNLGDNFAKAFDTTFLDDKGETQYVHQSSWGVSTRLIGGILMTHGDDSGLILPPRLAPIQVVVVPIWKKDEEKEAVMASVDSIISSLSNAGVRTHLDADQSKSPGWKFNQYEMKGVPIRIEVGPKDVAKGACVVARRDVPGKEGKEFGVSIEPAALETKVNDVLNDIQNSMLQKATEFRDANIVDVKTMDELKATIEAGKWARCGWEGTDEEEKAIKEETGATIRCFPFDQPAGEHTCLMSGKPAKEVCIFAKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7B8</accession>
    <name>A4S7B8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_43237</name>
        <name evidence="8" type="ORF">OSTLU_43350</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Cytoprotective ribonuclease (RNase) required for resistance to abiotic stresses, acting as a positive regulator of mRNA decapping during stress.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421245.1">
        <property type="nucleotide sequence ID" value="XM_001421208.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421279.1">
        <property type="nucleotide sequence ID" value="XM_001421242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7B8"/>
    <dbReference type="STRING" id="436017.A4S7B8"/>
    <dbReference type="GeneID" id="5005512"/>
    <dbReference type="GeneID" id="5005586"/>
    <dbReference type="Gramene" id="ABO99538">
        <property type="protein sequence ID" value="ABO99538"/>
        <property type="gene ID" value="OSTLU_43237"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99572">
        <property type="protein sequence ID" value="ABO99572"/>
        <property type="gene ID" value="OSTLU_43350"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43237"/>
    <dbReference type="KEGG" id="olu:OSTLU_43350"/>
    <dbReference type="eggNOG" id="KOG2039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005966_2_0_1"/>
    <dbReference type="OMA" id="ARCADHH"/>
    <dbReference type="OrthoDB" id="10023235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031332">
        <property type="term" value="C:RNAi effector complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000018">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000018">
        <property type="entry name" value="Serine/threonine-protein kinase 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016685">
        <property type="entry name" value="Silence_cplx_Nase-comp_TudorSN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF2">
        <property type="entry name" value="STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017179">
        <property type="entry name" value="RISC-Tudor-SN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="4"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="176"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="341"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="524"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="5">
        <location>
            <begin position="721"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR017179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="918" mass="99480" checksum="530063EF23EEF1CC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7R4</accession>
    <name>A4S7R4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421500.1">
        <property type="nucleotide sequence ID" value="XM_001421463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7R4"/>
    <dbReference type="GeneID" id="5005475"/>
    <dbReference type="Gramene" id="ABO99793">
        <property type="protein sequence ID" value="ABO99793"/>
        <property type="gene ID" value="OSTLU_27590"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27590"/>
    <dbReference type="HOGENOM" id="CLU_1868562_0_0_1"/>
    <dbReference type="OrthoDB" id="498672at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="137" mass="14279" checksum="5AEFB264CFFBFFA1" modified="2007-05-15" version="1">MLGLDYSSSDDDADTDVAEGVGKGVAEEDQSAVLAVKSVKPTGGLPSAAAMFSNEAETVERELSSTRAAAGAPTTIGTKRTAPTPALNPRPAQQKYSKSLGKINTLLPPQLKGRANKPTQDLEAFGIRTKKKAPARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7X0</accession>
    <name>A4S7X0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YqgF/RNase H-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421524.1">
        <property type="nucleotide sequence ID" value="XM_001421487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7X0"/>
    <dbReference type="STRING" id="436017.A4S7X0"/>
    <dbReference type="GeneID" id="5005434"/>
    <dbReference type="Gramene" id="ABO99817">
        <property type="protein sequence ID" value="ABO99817"/>
        <property type="gene ID" value="OSTLU_27647"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27647"/>
    <dbReference type="eggNOG" id="KOG0228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1236507_0_0_1"/>
    <dbReference type="OMA" id="ECCDRIV"/>
    <dbReference type="OrthoDB" id="513770at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317:SF4">
        <property type="entry name" value="POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="21222" checksum="261DB594C655CDD6" modified="2007-05-15" version="1">MSPSWFSQRRAPFTDAQTSSSSLEDELRAARRARGDVIALGVDYGARRVGLAVSNGGAAPRPLRTLTHSGTATTTSTVRAILDVALEECCDRIVVGIPVPPGRAAKDRRGRGRGAVQMHAVCARFAGEVADACARSTNAETKALVVYTYDESRTSKEASERIATSGGSNENGALDSASAAILLERYFDGSYGEAKLVKAANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S806</accession>
    <name>A4S806_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SERRATE/Ars2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_27682</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421677.1">
        <property type="nucleotide sequence ID" value="XM_001421640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S806"/>
    <dbReference type="STRING" id="436017.A4S806"/>
    <dbReference type="GeneID" id="5005784"/>
    <dbReference type="Gramene" id="ABO99970">
        <property type="protein sequence ID" value="ABO99970"/>
        <property type="gene ID" value="OSTLU_27682"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27682"/>
    <dbReference type="eggNOG" id="KOG2295">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_567859_0_0_1"/>
    <dbReference type="OMA" id="CARAHEF"/>
    <dbReference type="OrthoDB" id="498148at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031053">
        <property type="term" value="P:primary miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039727">
        <property type="entry name" value="SE/Ars2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007042">
        <property type="entry name" value="SERRATE/Ars2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021933">
        <property type="entry name" value="SERRATE/Ars2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165">
        <property type="entry name" value="ARSENITE-RESISTANCE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165:SF0">
        <property type="entry name" value="SERRATE RNA EFFECTOR MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04959">
        <property type="entry name" value="ARS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12066">
        <property type="entry name" value="SERRATE_Ars2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SERRATE/Ars2 N-terminal" evidence="6">
        <location>
            <begin position="66"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="SERRATE/Ars2 C-terminal" evidence="5">
        <location>
            <begin position="325"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO99970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="53703" checksum="5DB9D5DE6EF230EF" modified="2007-05-15" version="1">MDVDQEQYYDDGGGGSRRRGRGRGDRGGDRHHPYGDDGHRGGRGGGRGGGGRGRGRRDDGALSFRDFCYKYLRDDTTPAEAERRYEEYKKENQEAFYERYFRDHRHDEGERARNDPRVLVETLKRRDELACARAHEFFASKADGSLRIYDEGDAEGKDADMGEGEHQGEHQQEKRRSMVPIEAWHPTRLGTDYKQTGRLIAALDAEKGIDNNPLLDGDEDSGMDAEAAEDDVAALEALGNEASTPEKLDERLCYLVRVHGVDYYRRISEMQPVTFLEKLPSAFAKRDPKPEDTPVSSIAQNPYAVRLFATVDANVKRRIAEGDPQVKKLGTSEIESKLDEWIQSCVVKHDEQRFGCTLSTKLFVAEEFVIKHIKTKQAHHVEDMRERLFDEQYRKNVVEFLKYDEHRKENKKDHKKRFGGVMMMQVPGSGPDGQFVQVPMGTGGAKMIKGMARYTDLDAAVTESRVVIDYGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S850</accession>
    <name>A4S850_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dephospho-CoA kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_40654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421702.1">
        <property type="nucleotide sequence ID" value="XM_001421665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S850"/>
    <dbReference type="STRING" id="436017.A4S850"/>
    <dbReference type="GeneID" id="5005602"/>
    <dbReference type="Gramene" id="ABO99995">
        <property type="protein sequence ID" value="ABO99995"/>
        <property type="gene ID" value="OSTLU_40654"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40654"/>
    <dbReference type="eggNOG" id="KOG3220">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057180_3_0_1"/>
    <dbReference type="OMA" id="HCSEEIR"/>
    <dbReference type="OrthoDB" id="247245at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02022">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00152">
        <property type="entry name" value="dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="21399" checksum="1C26AB5FB9A21383" modified="2007-05-15" version="1">MSRSTTRLGLTGSIGMGKSTVAAMFRDLGVAVMDADAVVYDLYAPDGAAVAVVAEMFGDGVLDAATGAIDRAKLGAIVIGDDAKMRALESAVHPLVERAREAFVEAHANDDVVVFDIPLLYEKEYEASVDAVCVVSTGDEATQRARVLKRDGMTEEKFNGIAARQIPDAEKRAKADYVIDTSCSLAQTRARVEEILSLVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S860</accession>
    <name>A4S860_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421569.1">
        <property type="nucleotide sequence ID" value="XM_001421532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S860"/>
    <dbReference type="GeneID" id="5005607"/>
    <dbReference type="Gramene" id="ABO99862">
        <property type="protein sequence ID" value="ABO99862"/>
        <property type="gene ID" value="OSTLU_27735"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27735"/>
    <dbReference type="HOGENOM" id="CLU_560629_0_0_1"/>
    <dbReference type="OMA" id="EEKWMEQ"/>
    <dbReference type="OrthoDB" id="10574540at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="45473" checksum="93030B8C8010EA57" modified="2007-05-15" version="1">MPMRAANDGWNRFGARSTYIAGLIETEDGDFDDEEFPTDYRAELEIRLSQIARLEDALKDANARAAVARREENVEAQMSKFRTHLQNVQRELENVKRERDAYKMKWHASSGPAEAKTREARRANQRTMATQTTFDDDEKKKDAEVAPSKKEIRAAEEKWMEQARLFEQKFERQMEISNEYDRKLRDERTRLMRSEARYEARIEELTTKQAELIAELSVRGVGTAPTSEQTVDFSRNQFAEYAKIGAEAATTRAFPDASPIATLHPPSPPMEMFESPSANFDDAETKSDVEVEKISPAKFESAKKLNFAAALDDFSSSDDEDVNRRPMPPPQIPTTNNMQAPTPPLARTSSARKPLRLTVAVAKIVMLGYSQRDAIEALKHVDGNDVHDALAWLERRARTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8C6</accession>
    <name>A4S8C6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase family 25 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_25601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421598.1">
        <property type="nucleotide sequence ID" value="XM_001421561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8C6"/>
    <dbReference type="GeneID" id="5005681"/>
    <dbReference type="Gramene" id="ABO99891">
        <property type="protein sequence ID" value="ABO99891"/>
        <property type="gene ID" value="OSTLU_25601"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25601"/>
    <dbReference type="HOGENOM" id="CLU_599072_0_0_1"/>
    <dbReference type="OMA" id="FNYHCKL"/>
    <dbReference type="OrthoDB" id="47375at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673240" description="Glycosyltransferase family 25 protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="51261" checksum="6C44C1AD0FA64C7A" modified="2007-05-15" version="1">MGARARWARAMAAVTMVTLATSIAAAERVEREDAVRMYYVNARGATTKRLEMERAVVALDARARRIERVDAKRRSTLLMTYETATCGRGRFAPSAHAERRERFGEEYLNALGTSLSHLEAVYAAYDDGASVALIMEDDARWDLLPTWSSDLEKFVERLPEDWTVTQLSALGDYAETTKLFYDWQRERKNAPGQSLTTLPKGSRRLSGTQAYLISRKGMSRLVKAYRSPAGKTDVCSMTCVELEECVLADGVHLDEKYRVATPPLFVERSPSSDFLDSSRNMILSWAVSLSLTQGKAANLRMDGDMIRDVLAEGLKVPEHLKPNTFMEHFNYHCKLNHGGGSKCSIKKAYLVNQKPPRMEEPALAEEAPVDAEENFRGHNASALGRVVMSRRDLAPKETSIWSEYSKSTPFISMFVFGALTTFVLAASFVFAKTRPESSRDELQTILPIDPQTEEYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8K8</accession>
    <name>A4S8K8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421783.1">
        <property type="nucleotide sequence ID" value="XM_001421746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8K8"/>
    <dbReference type="GeneID" id="5005750"/>
    <dbReference type="Gramene" id="ABP00077">
        <property type="protein sequence ID" value="ABP00077"/>
        <property type="gene ID" value="OSTLU_18395"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18395"/>
    <dbReference type="HOGENOM" id="CLU_1663659_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="159" mass="17371" checksum="9AE7487E0D3561AD" modified="2007-05-15" version="1">MGLLYVVGELFAFHATLCWRRMSTYEYIVAERAIAADARAAAIERGEDGSDIQVRTSVCRLCRLPEAYAPDREKTAPKTPKAPRAIKTKAAEPPPPSASAKERGGLFSPFKARANKSKVFTDEPDSPPPVKREEALGHFDETLQALSDARGASRKGGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8L2</accession>
    <name>A4S8L2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421786.1">
        <property type="nucleotide sequence ID" value="XM_001421749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8L2"/>
    <dbReference type="STRING" id="436017.A4S8L2"/>
    <dbReference type="GeneID" id="5005723"/>
    <dbReference type="Gramene" id="ABP00080">
        <property type="protein sequence ID" value="ABP00080"/>
        <property type="gene ID" value="OSTLU_27888"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27888"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_0_1_1"/>
    <dbReference type="OMA" id="DIQACLF"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044999">
        <property type="entry name" value="CbbY-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42896:SF4">
        <property type="entry name" value="OS08G0485900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42896">
        <property type="entry name" value="XYLULOSE-1,5-BISPHOSPHATE (XUBP) PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="297" mass="31794" checksum="6F2A237E32D102FE" modified="2007-05-15" version="1">MTTSTRVERGARTTAAKKTTKTTRRATTTRANAGSNTKNARFALLFDCDGVIVETEELHRLAYNGAFEAFDLKIDGEGVEWVVKYYDVLQNTVGGGKPKMRWHFNEDKKAWPTSTMFAEAPSSDADRDALIDALQDKKTEIYKKIVEEVAVARPGVLALMDEAIADPSIAVGICSAATKAGFEKVVNSVVGVERLSKLDVLMAGDDVTRKKPDPLIYNLARDKVGLPASKCLVVEDSIVGLRAAVGADMACLITPCGSNIGADFMGEGASKVVNDLGAVKLAMLFPEGAETPAFDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8L9</accession>
    <name>A4S8L9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DMT family transporter: phosphate/phosphoenolpyruvate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_4851</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421789.1">
        <property type="nucleotide sequence ID" value="XM_001421752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8L9"/>
    <dbReference type="GeneID" id="5005791"/>
    <dbReference type="Gramene" id="ABP00083">
        <property type="protein sequence ID" value="ABP00083"/>
        <property type="gene ID" value="OSTLU_4851"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4851"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022332_3_1_1"/>
    <dbReference type="OMA" id="MLKAFAP"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="7"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="288" mass="31671" checksum="A51D7B11D1987437" modified="2007-05-15" version="1" fragment="single">YAVAYLLVATVLILANKHLITETSFNCPVFVSSLGSWFGWGVAAAAIKLDPKRMSHRLSAREWTANILPIGFCTALSLAAANVAYSYLSLSFIQMLKAFAPVVCYFTLVAFGLDRWSGRIIATLSVVMIGCFIAAWGEAHVTMFGLACMLTAEIAEAFRSVGIQYLISNKKFSLFNGMYYFSPATLVFLMALSLIFEREELFRTENIATFTRYWYLFFICATFGFAVNYVCLGVVKHAGSLMVKTMSQLKNVAVIGAAMFLYGDEVSVTEIVGYAVATAGFVAFNHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9C1</accession>
    <name>A4S9C1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">E3 ubiquitin-protein ligase listerin</fullName>
            <ecNumber evidence="5 15">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">RING-type E3 ubiquitin transferase listerin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_18578</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the ribosome quality control complex (RQC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the LTN1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5 15"/>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421908.1">
        <property type="nucleotide sequence ID" value="XM_001421871.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S9C1"/>
    <dbReference type="GeneID" id="5006079"/>
    <dbReference type="Gramene" id="ABP00202">
        <property type="protein sequence ID" value="ABP00202"/>
        <property type="gene ID" value="OSTLU_18578"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18578"/>
    <dbReference type="eggNOG" id="KOG0803">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_234798_0_0_1"/>
    <dbReference type="OMA" id="HAEECAT"/>
    <dbReference type="OrthoDB" id="6108at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16491">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000038">
        <property type="entry name" value="E3 ubiquitin-protein ligase listerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039795">
        <property type="entry name" value="LTN1/Rkr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054477">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054476">
        <property type="entry name" value="Ltn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054478">
        <property type="entry name" value="LTN1_UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039804">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE LISTERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389">
        <property type="entry name" value="ZINC FINGER PROTEIN 294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22958">
        <property type="entry name" value="Ltn1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22999">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23009">
        <property type="entry name" value="UBC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
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        <property type="entry name" value="ZF_RING_2"/>
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    </dbReference>
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    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="1689"/>
            <end position="1735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU367090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABP00202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1744" mass="188524" checksum="93358970392223E1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9G2</accession>
    <name>A4S9G2_OSTLU</name>
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        <submittedName>
            <fullName evidence="6">Putative mitochondrial ribosomal protein L15</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="primary">MRPL15</name>
        <name evidence="6" type="ORF">OSTLU_28191</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
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        <property type="component" value="Chromosome 16"/>
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    </dbReference>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
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        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L27A"/>
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    </dbReference>
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        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <begin position="116"/>
            <end position="205"/>
        </location>
    </feature>
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    </feature>
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            <end position="257"/>
        </location>
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            <end position="79"/>
        </location>
    </feature>
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        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="257" mass="27429" checksum="3359DA72E961C0BB" modified="2007-05-15" version="1">MGGAAPPRDDETRGFDFYDAADVGVVRGPGTVIEHDTGGVLALNALRDVDGARKNRKRVGRGVGSGKGKTSGRGHKGQKARSGGGPRLGFEGGQTPLRLTLPKRGAHNPHAMTFDVVNLNALRAHVEAGRFGEYDYENPRVLTMKDFVDAGLSNRKIKHGVKILAGALGDDAEGADDAFIKVRLEVSRASAKAKEIIERAGGSVTRVHYNRLGLRALLQPEKFPRGLPKPARAPPKIRPFIDREGTLPAPAPLEADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9P0</accession>
    <name>A4S9P0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_41988</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422100.1">
        <property type="nucleotide sequence ID" value="XM_001422063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9P0"/>
    <dbReference type="STRING" id="436017.A4S9P0"/>
    <dbReference type="GeneID" id="5006262"/>
    <dbReference type="Gramene" id="ABP00417">
        <property type="protein sequence ID" value="ABP00417"/>
        <property type="gene ID" value="OSTLU_41988"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41988"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_1"/>
    <dbReference type="OMA" id="KEQWLFK"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="61"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="408" mass="43787" checksum="FB6C6F6A8F5F6BDF" modified="2007-05-15" version="1">MEVELRAEGEHFNSQAASDALFSVDEAWGKNLVGALILELYSELQNDDKDTTIGFAALAQGEDLVPFKYRLPDMTPTSVEVKVEYCGLCGSDDHLIVGDYGEYAVWPQVCGHEVVGTVTQVGTAVTTLKAGQRVGVGWQSSSCHDCEWCARGDEQLCSSVGCTCCEGNKGGFADRMRLNDSQFCYKIPDALSSAEVAPLLCGGQTVWTPLNEQTKSSDRVGILGLGGLGHMAIKFAKALGREVTAISSSASKRADALSHGASRFLVHTNQEEMDAAASSLDFILVTIATNKEVDFAKFFPLLRPRGTICFVGMCPPIQADVFTLGFTMNNITTSNTGGKKDMVQMLEFCARHKIGASVAVSPLSEINTAITALRTGESHFRHVLVNDVSSGSQHRRMASAFGSGFPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9S8</accession>
    <name>A4S9S8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_28301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422224.1">
        <property type="nucleotide sequence ID" value="XM_001422187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9S8"/>
    <dbReference type="STRING" id="436017.A4S9S8"/>
    <dbReference type="GeneID" id="5006177"/>
    <dbReference type="Gramene" id="ABP00541">
        <property type="protein sequence ID" value="ABP00541"/>
        <property type="gene ID" value="OSTLU_28301"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28301"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058290_0_0_1"/>
    <dbReference type="OMA" id="KGCQLAR"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000001">
        <property type="entry name" value="14-3-3 gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="3">
        <location>
            <begin position="12"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="261" mass="29856" checksum="F909648E041FBD61" modified="2007-05-15" version="1">MSEKEDLSALKREDLVYKAKLAEQAERYEEMMDYMSEVTLKSSEEELSVEERNLLSVAFKNVIGARRASWRIVSSIETKEEAKHSKESDKCKLIAAYKANVEKELTDICTRILDLLKNHLEDRCSAGESKVFYKKMKGDYWRYLAEFKGGSERKEAAEETLLAYKSAEQTAEAELASTHPIRLGLALNFSVFYYEILNAPERACQMAKKAFDEAISELDTLGEESYKDSTLIMQLLRDNLTLWTSDMDESAQTGQDVDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9T3</accession>
    <name>A4S9T3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422226.1">
        <property type="nucleotide sequence ID" value="XM_001422189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9T3"/>
    <dbReference type="GeneID" id="5006180"/>
    <dbReference type="Gramene" id="ABP00543">
        <property type="protein sequence ID" value="ABP00543"/>
        <property type="gene ID" value="OSTLU_28307"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28307"/>
    <dbReference type="HOGENOM" id="CLU_1899691_0_0_1"/>
    <dbReference type="OMA" id="KTRVTCY"/>
    <dbReference type="OrthoDB" id="10388424at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="134" mass="14876" checksum="D34F8091578B28ED" modified="2007-05-15" version="1">MVKTRVTCYFPVENAREAKLGAFAVWYVDVDVEATDTKTDVRKAIALATGAKFSRLKIRLGMFNELLAFEDGRYGAVLKVGSCGASAATRDERLLTAHELNDLGAGSASDLPDWDPSKYDGRYGWVQEVKEHWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA69</accession>
    <name>A4SA69_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422328.1">
        <property type="nucleotide sequence ID" value="XM_001422291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA69"/>
    <dbReference type="GeneID" id="5006371"/>
    <dbReference type="Gramene" id="ABP00645">
        <property type="protein sequence ID" value="ABP00645"/>
        <property type="gene ID" value="OSTLU_28449"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28449"/>
    <dbReference type="HOGENOM" id="CLU_2709243_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="73" mass="8041" checksum="AF1D46425B6D3B60" modified="2007-05-15" version="1">MGFKYQSIPVFTDSSTSLSQGKREGNAWSEGCKQYEIELSRAHSMRTSEGAAKTASRASESYTTTSKLRNKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAC1</accession>
    <name>A4SAC1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_25795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422360.1">
        <property type="nucleotide sequence ID" value="XM_001422323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAC1"/>
    <dbReference type="STRING" id="436017.A4SAC1"/>
    <dbReference type="GeneID" id="5006418"/>
    <dbReference type="Gramene" id="ABP00677">
        <property type="protein sequence ID" value="ABP00677"/>
        <property type="gene ID" value="OSTLU_25795"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25795"/>
    <dbReference type="eggNOG" id="KOG0401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_452249_0_0_1"/>
    <dbReference type="OMA" id="PSKPAME"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
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    </dbReference>
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        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
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    </dbReference>
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        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
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        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="MIF4G"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="499"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="24"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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            <end position="170"/>
        </location>
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        <location>
            <begin position="418"/>
            <end position="448"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="689" mass="71859" checksum="D5B909CA273544A7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAL5</accession>
    <name>A4SAL5_OSTLU</name>
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        <recommendedName>
            <fullName evidence="11">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_29301</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Gramene" id="ABP00769">
        <property type="protein sequence ID" value="ABP00769"/>
        <property type="gene ID" value="OSTLU_29301"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_497309_0_0_1"/>
    <dbReference type="OMA" id="FAPVSEM"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING-CH"/>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
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        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065:SF3">
        <property type="entry name" value="FI20425P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143456">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="11">
        <location>
            <begin position="17"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="219"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="219"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="548" mass="60878" checksum="CC0DEE59940B8F4E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAN5</accession>
    <name>A4SAN5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nuclear transcription factor Y subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_29323</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422464.1">
        <property type="nucleotide sequence ID" value="XM_001422427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAN5"/>
    <dbReference type="STRING" id="436017.A4SAN5"/>
    <dbReference type="GeneID" id="5006698"/>
    <dbReference type="Gramene" id="ABP00781">
        <property type="protein sequence ID" value="ABP00781"/>
        <property type="gene ID" value="OSTLU_29323"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29323"/>
    <dbReference type="HOGENOM" id="CLU_2041965_0_0_1"/>
    <dbReference type="OrthoDB" id="1097733at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="13509" checksum="F4FE9FD87B94BCAD" modified="2007-05-15" version="1">MDAAVYVNAKQYDAIVRRRQKRARANATRTPGVVNAKHPSRSAHAKNRIRGKNGKYLTRDELLRGLGGPEGRARAEAREREIAEREAKRVERAAVREATKARARAQRAAADAVRAAKKSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAR1</accession>
    <name>A4SAR1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-methionine-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_43507</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422479.1">
        <property type="nucleotide sequence ID" value="XM_001422442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAR1"/>
    <dbReference type="STRING" id="436017.A4SAR1"/>
    <dbReference type="GeneID" id="5006709"/>
    <dbReference type="Gramene" id="ABP00796">
        <property type="protein sequence ID" value="ABP00796"/>
        <property type="gene ID" value="OSTLU_43507"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43507"/>
    <dbReference type="eggNOG" id="KOG1635">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_3_1"/>
    <dbReference type="OMA" id="TEKMFWR"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050162">
        <property type="entry name" value="MsrA_MetSO_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799:SF2">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="8">
        <location>
            <begin position="48"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="27426" checksum="06ECD74CC9CDCF91" modified="2007-05-15" version="1">MMGLGGDGIVAAADALPGRAQAMRVSDQHYVLKGHAMRAPFPENLERATFATGCFWGTEKMFWRLPGVHSTSVGYVGGRATNPTYEEVCSGSTGHTECVKVTYDPRKVSFADLLAMHWTCHDPTQGDGQGNDRGTQYRSGIYCTTDAQLAMAKDSAKAYGEALRAAGKSGAITSEIKGPGDTFYYAEDYHQQYLAKPGSRPYCSAQPTGVPMPVTWLETNGAKFGAGFWAKYGPKPTCTIGVPNEPISSEDASAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="115" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAW6</accession>
    <name>A4SAW6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_51954</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422676.1">
        <property type="nucleotide sequence ID" value="XM_001422639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAW6"/>
    <dbReference type="STRING" id="436017.A4SAW6"/>
    <dbReference type="GeneID" id="5006568"/>
    <dbReference type="Gramene" id="ABP00993">
        <property type="protein sequence ID" value="ABP00993"/>
        <property type="gene ID" value="OSTLU_51954"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51954"/>
    <dbReference type="eggNOG" id="KOG0478">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_7_2_1"/>
    <dbReference type="OMA" id="AFFKCNV"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000347">
        <property type="term" value="C:THO complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="15">
        <location>
            <begin position="350"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="298"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABP00993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="755" mass="84457" checksum="C21872D7C3824C1E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAZ0</accession>
    <name>A4SAZ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_89710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422685.1">
        <property type="nucleotide sequence ID" value="XM_001422648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAZ0"/>
    <dbReference type="GeneID" id="5006583"/>
    <dbReference type="Gramene" id="ABP01002">
        <property type="protein sequence ID" value="ABP01002"/>
        <property type="gene ID" value="OSTLU_89710"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89710"/>
    <dbReference type="eggNOG" id="KOG2733">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031002_0_2_1"/>
    <dbReference type="OMA" id="GPYQLYG"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="2">
        <location>
            <begin position="15"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="436" mass="46579" checksum="9075E9C9212F149C" modified="2007-05-15" version="1">MATVAARATREFDLIVYGANGFTGALAVDYLARKYPHLSIAIAGRDAAKIRARADATRDARGVTFPTVVARDAASREAMVRRARTVLTFAGPYDADAARALAASCADAGTDYCDITGEPQFVRDVVETCHERAKARGCALVSCVGYDSVPWDLGTALASEATMKRGGAAEIDVARGHAGRSRGGVSGGTIASAANVVAKPKSETRGMGDPHFFAKCAGGWADKPDVEAAKRWPSPQGTWAFDEDTKRWTMPSIMAGINAKVVARSYALNPERYGKNFRYDESDLCASKKNAILGTLTLGAFGAAFVVPPLRWLMRKTILPKQGEGPSEDTRENGFSHVYVVANGRDAKGEAVDSYCCEFEFIKADPGYKGTAALACEAALCLAIPEERARLDFAKEGSGGCFTPSACMGHVLMERLNNAENFSVKVQKLKDTVFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB12</accession>
    <name>A4SB12_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422536.1">
        <property type="nucleotide sequence ID" value="XM_001422499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB12"/>
    <dbReference type="GeneID" id="5006753"/>
    <dbReference type="Gramene" id="ABP00853">
        <property type="protein sequence ID" value="ABP00853"/>
        <property type="gene ID" value="OSTLU_29451"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29451"/>
    <dbReference type="eggNOG" id="ENOG502S34D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102705_0_0_1"/>
    <dbReference type="OrthoDB" id="496066at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39444">
        <property type="entry name" value="SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39444:SF3">
        <property type="entry name" value="SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="166" mass="19329" checksum="E3D2BE41259AF393" modified="2007-05-15" version="1">MSRADDEWATSERTWASLFGVLERNGYAKKKLWAPFVYDGDAGRRMRSAGFERVVHRRADFFERVRDGVFVRSLDAVVDNPPYTGKGMKERILKALRDAEVPFCLLLPLGVLHAAFVRDILEETHVQVIVPRKCYVFKKGGTEVPFKFLCWLCYKMELKRDLYFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB53</accession>
    <name>A4SB53_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_1733</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422556.1">
        <property type="nucleotide sequence ID" value="XM_001422519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB53"/>
    <dbReference type="STRING" id="436017.A4SB53"/>
    <dbReference type="GeneID" id="5006614"/>
    <dbReference type="Gramene" id="ABP00873">
        <property type="protein sequence ID" value="ABP00873"/>
        <property type="gene ID" value="OSTLU_1733"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_1733"/>
    <dbReference type="eggNOG" id="KOG0345">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_4_1"/>
    <dbReference type="OMA" id="AYKEHEC"/>
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        <property type="component" value="Chromosome 20"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="RHEA"/>
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    <dbReference type="GO" id="GO:0003723">
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="DEADc_DDX55"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
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    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="32"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="256"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="515"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="517"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP00873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="583" mass="65252" checksum="A47A65F1DBA6975F" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBU3</accession>
    <name>A4SBU3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_19237</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABP01195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001422799.1"/>
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        <property type="protein sequence ID" value="ABP01195"/>
        <property type="gene ID" value="OSTLU_19237"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19237"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
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    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF14">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="179"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="380"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="646"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="526"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="646"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="695"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP01195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="710" mass="77694" checksum="56C794C094C5EFEF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQJ2</accession>
    <name>A4RQJ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD/PDEase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_39912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415398.1">
        <property type="nucleotide sequence ID" value="XM_001415361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQJ2"/>
    <dbReference type="STRING" id="436017.A4RQJ2"/>
    <dbReference type="GeneID" id="4999547"/>
    <dbReference type="Gramene" id="ABO93690">
        <property type="protein sequence ID" value="ABO93690"/>
        <property type="gene ID" value="OSTLU_39912"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39912"/>
    <dbReference type="eggNOG" id="KOG2681">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026821_1_3_1"/>
    <dbReference type="OMA" id="QVHGYIK"/>
    <dbReference type="OrthoDB" id="9991235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008832">
        <property type="term" value="F:dGTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050135">
        <property type="entry name" value="dGTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373">
        <property type="entry name" value="DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373:SF4">
        <property type="entry name" value="DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19276">
        <property type="entry name" value="HD_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="1">
        <location>
            <begin position="91"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="500" mass="57545" checksum="11242AFE647BBE68" modified="2007-05-15" version="1">MELRAEDDDDDPFIAQLSQIAHEPRVHVGEENAAATAYCAGRRSRGKTFNDPVHGHMYFNPKLCDVIDTPQMQRLRELKQLGTSYYVFPGAGHNRFEHSLGTCHLANTVFESIKRSAPRHGLGLTVEDKLCVQLAGLCHDMGHGPFSHVFDNEFLPLRHGWDPKVVAPWNHERMGVDMFSWCLDDNHIDLEPQVVRRVCDFITSNEEGAKEKRFLFDIIANKQNGIDVDKFEYLLRDSYQAGVRMSVDTMRLTSHMKVIDDRICFKSSEANNVYALFHSRASMHQSVYTHKKAKAVEYMVVDALVEADIAWNGRISNSIWSVEDFIAMDDTLLKQIEFCDDPALAKARDIVRRIRRRELYRFVNEYTVPEDQVVDFKPVEAKDITSCQGTNNIPGGLKPDDIIVQCLKIDYGQKGHKDPVENVRFFHYWDDETSCSIAKEQISSLLPRNFVHRVVRVFSRRREPEYIEATAQAFSNFQRRQLGKEAQITPVKRQRFSNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQK0</accession>
    <name>A4RQK0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415745.1">
        <property type="nucleotide sequence ID" value="XM_001415708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQK0"/>
    <dbReference type="STRING" id="436017.A4RQK0"/>
    <dbReference type="GeneID" id="4999769"/>
    <dbReference type="Gramene" id="ABO94037">
        <property type="protein sequence ID" value="ABO94037"/>
        <property type="gene ID" value="OSTLU_13605"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13605"/>
    <dbReference type="eggNOG" id="KOG2810">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_678610_0_0_1"/>
    <dbReference type="OMA" id="YEMHEVM"/>
    <dbReference type="OrthoDB" id="498197at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="406" mass="43366" checksum="C2FD07DB9C4910BB" modified="2007-05-15" version="1">MELAVSGGSLRALHRSIAFLSRVGPEVLIDASARDETLTLKSVNAARSAFARVAVRASAFDAREITARGGRAQTCALAKHVMASLRSHARADVVVVTLDDEDDEGREARRLRVTTTSAKSGTKKTYEMHEVMDAEHVDAEIDAEAMPAKVVSRAKTLLTLLAHFSSAAREDVTLTCGIESDVCVDGDAAGAAKIVTLSSYLSPGGGLSQALQTSISLRRDDESILFYRNTAAAPVEVTVNLKDLRSIVQLCESSDVDVAIYCAQAGAPVVVKPTADFKMFHQRDAFGNQPQHTTAPASVDFEAELVLASMLPPEDASAVEPSQCEQPRVEAPAPLQNAPLGSQPWSAVPDSENASQREVGGGVDAPSRPWGREAPNDAATTVLNDNDDWAHDEFVEATPPEKRQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRA2</accession>
    <name>A4RRA2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pullulanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_39745</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415537.1">
        <property type="nucleotide sequence ID" value="XM_001415500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRA2"/>
    <dbReference type="STRING" id="436017.A4RRA2"/>
    <dbReference type="CAZy" id="CBM41">
        <property type="family name" value="Carbohydrate-Binding Module Family 41"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM48">
        <property type="family name" value="Carbohydrate-Binding Module Family 48"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="GeneID" id="4999994"/>
    <dbReference type="Gramene" id="ABO93829">
        <property type="protein sequence ID" value="ABO93829"/>
        <property type="gene ID" value="OSTLU_39745"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39745"/>
    <dbReference type="eggNOG" id="KOG0470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004744_5_0_1"/>
    <dbReference type="OMA" id="DKIVPWY"/>
    <dbReference type="OrthoDB" id="204980at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010303">
        <property type="term" value="F:limit dextrinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051060">
        <property type="term" value="F:pullulanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005983">
        <property type="term" value="P:starch catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd11341">
        <property type="entry name" value="AmyAc_Pullulanase_LD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10315">
        <property type="entry name" value="CBM41_pullulanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02860">
        <property type="entry name" value="E_set_Pullulanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1130">
        <property type="entry name" value="Rab geranylgeranyltransferase alpha-subunit, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005323">
        <property type="entry name" value="CBM41_pullulanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011839">
        <property type="entry name" value="Pullul_strch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024561">
        <property type="entry name" value="Pullul_strch_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040671">
        <property type="entry name" value="Pullulanase_N2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02103">
        <property type="entry name" value="pullul_strch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43002">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03714">
        <property type="entry name" value="PUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11852">
        <property type="entry name" value="Pullul_strch_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17967">
        <property type="entry name" value="Pullulanase_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Pullulanase carbohydrate-binding module 41" evidence="7">
        <location>
            <begin position="69"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Pullulanase N2" evidence="9">
        <location>
            <begin position="182"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 13 N-terminal" evidence="6">
        <location>
            <begin position="303"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-1,6-glucosidases pullulanase-type C-terminal" evidence="8">
        <location>
            <begin position="889"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO93829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1062" mass="117010" checksum="442BB33184B8ECFC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRI5</accession>
    <name>A4RRI5_OSTLU</name>
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        <recommendedName>
            <fullName evidence="10">Histone deacetylase interacting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_239</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRI5"/>
    <dbReference type="STRING" id="436017.A4RRI5"/>
    <dbReference type="GeneID" id="4999658"/>
    <dbReference type="KEGG" id="olu:OSTLU_239"/>
    <dbReference type="eggNOG" id="KOG4204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007140_1_0_1"/>
    <dbReference type="OMA" id="KPGINAC"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
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    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="10">
        <location>
            <begin position="316"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="518"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="609"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="518"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="612"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="655"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO93867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="962" mass="110149" checksum="B57AE1E7ADF6DEF1" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRK0</accession>
    <name>A4RRK0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29045</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415583.1">
        <property type="nucleotide sequence ID" value="XM_001415546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRK0"/>
    <dbReference type="STRING" id="436017.A4RRK0"/>
    <dbReference type="GeneID" id="4999476"/>
    <dbReference type="Gramene" id="ABO93875">
        <property type="protein sequence ID" value="ABO93875"/>
        <property type="gene ID" value="OSTLU_29045"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29045"/>
    <dbReference type="eggNOG" id="ENOG502RV78">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1043490_0_0_1"/>
    <dbReference type="OMA" id="TECVHAT"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="GOLD" evidence="8">
        <location>
            <begin position="6"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO93875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="267" mass="29651" checksum="FFFD2BAAB81A3592" modified="2007-05-15" version="1">MDVVVHARFVLREGTDVEGTLRDARGAEAARWTFDERRSDGDADDRGRAKEIEVKTRGCGDYEVCFHHARGKSKEARIEVDYFQALREPSANGDDVEARIEDESEKAKRERAKRSTSEGLRTDGVLSVSSKASGLNNWVQQLREEMNYLRVRAERHKKTVESNARRMVRTTFIEVCVLIGVTGVQVMTVKRFFDVQTRSHERFRTQFGGASSAFAGGFEAASRHVAGPMADAFSSGANAAQRGVAGLLKSIGRSSAPSRARHDYHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRV6</accession>
    <name>A4RRV6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="4">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_29150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="4"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415634.1">
        <property type="nucleotide sequence ID" value="XM_001415597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRV6"/>
    <dbReference type="STRING" id="436017.A4RRV6"/>
    <dbReference type="GeneID" id="4999808"/>
    <dbReference type="Gramene" id="ABO93926">
        <property type="protein sequence ID" value="ABO93926"/>
        <property type="gene ID" value="OSTLU_29150"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29150"/>
    <dbReference type="eggNOG" id="KOG2367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022158_0_1_1"/>
    <dbReference type="OMA" id="NTMRMLV"/>
    <dbReference type="OrthoDB" id="2015253at2759"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010177">
        <property type="term" value="F:methylthioalkylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07940">
        <property type="entry name" value="DRE_TIM_IPMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.260:FF:000001">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000010">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002086">
        <property type="entry name" value="PRK00915.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF9">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="11">
        <location>
            <begin position="76"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO93926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="624" mass="66133" checksum="8FDE3971DA81A4CC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS55</accession>
    <name>A4RS55_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415681.1">
        <property type="nucleotide sequence ID" value="XM_001415644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS55"/>
    <dbReference type="GeneID" id="4999680"/>
    <dbReference type="Gramene" id="ABO93973">
        <property type="protein sequence ID" value="ABO93973"/>
        <property type="gene ID" value="OSTLU_14022"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14022"/>
    <dbReference type="eggNOG" id="ENOG502SBBW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_934890_0_0_1"/>
    <dbReference type="OMA" id="KMRLFAR"/>
    <dbReference type="OrthoDB" id="568147at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="326" mass="35829" checksum="BB08ED2ACD8837DF" modified="2007-05-15" version="1">MTELTPYELERERRIAVNRQRMLALGLRRDDVRMHDASRARASGKDSKAAATARAVKSPTKSRRARDASERDDVRRSSRRRGIAPERFASTSDDARESDGGEGSRRGDDETTAETRALHERAAEAYAARNAGKQARAAIVGTTSYNHTLMRVKTMDERGLERRMHAIRNARGKHCVTKMRLFARVLFLEGYEDLAGMCVEALEELVAELGDPDEEDMKAAAVDIAREERDGANFRCDAATDLSDPSVYADVVRIEAKAVSAMAVDEKPTSAALAGIPNANRWQVAAAALVGADGALKPSGNVVSFDKNGAYHVARVTPEMRKKMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS68</accession>
    <name>A4RS68_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MGS-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_14033</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416026.1">
        <property type="nucleotide sequence ID" value="XM_001415989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS68"/>
    <dbReference type="STRING" id="436017.A4RS68"/>
    <dbReference type="GeneID" id="4999406"/>
    <dbReference type="Gramene" id="ABO94318">
        <property type="protein sequence ID" value="ABO94318"/>
        <property type="gene ID" value="OSTLU_14033"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14033"/>
    <dbReference type="eggNOG" id="KOG2555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016316_5_1_1"/>
    <dbReference type="OMA" id="IKHNNPC"/>
    <dbReference type="OrthoDB" id="6017153at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010319">
        <property type="term" value="C:stromule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.20:FF:000001">
        <property type="entry name" value="Bifunctional purine biosynthesis protein PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000001">
        <property type="entry name" value="Bifunctional purine biosynthesis protein PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002049">
        <property type="entry name" value="PRK00881.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00050488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="519" mass="55375" checksum="251E7E410D03D041" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSR4</accession>
    <name>A4RSR4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RPC10 subunit of RNA polymerases I, II, and III, probable</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Rpc10</name>
        <name evidence="6" type="ORF">OSTLU_119610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416203.1">
        <property type="nucleotide sequence ID" value="XM_001416166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSR4"/>
    <dbReference type="STRING" id="436017.A4RSR4"/>
    <dbReference type="GeneID" id="5000159"/>
    <dbReference type="Gramene" id="ABO94496">
        <property type="protein sequence ID" value="ABO94496"/>
        <property type="gene ID" value="OSTLU_119610"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119610"/>
    <dbReference type="eggNOG" id="KOG3507">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179456_0_1_1"/>
    <dbReference type="OMA" id="IYLCADC"/>
    <dbReference type="OrthoDB" id="563927at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000418">
        <property type="term" value="C:RNA polymerase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.30:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerases II, IV and V subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.30">
        <property type="entry name" value="RNA polymerase ii, chain L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006591">
        <property type="entry name" value="RNAP_P/RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039747">
        <property type="entry name" value="RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056:SF2">
        <property type="entry name" value="GEO11084P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03604">
        <property type="entry name" value="Zn_ribbon_RPAB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00659">
        <property type="entry name" value="RPOLCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="56" mass="6230" checksum="C0BCC05759E9DEEA" modified="2007-05-15" version="1">MYQEPKSSGGGGVAYNCGDCGSEVLLRPGDVIICRECGYRILYKKRTKQVVQFEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSZ3</accession>
    <name>A4RSZ3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Orfan protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Osp2</name>
        <name evidence="1" type="ORF">OSTLU_119529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416163.1">
        <property type="nucleotide sequence ID" value="XM_001416126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSZ3"/>
    <dbReference type="GeneID" id="5000312"/>
    <dbReference type="Gramene" id="ABO94456">
        <property type="protein sequence ID" value="ABO94456"/>
        <property type="gene ID" value="OSTLU_119529"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119529"/>
    <dbReference type="HOGENOM" id="CLU_2578188_0_0_1"/>
    <dbReference type="OMA" id="MDGIWEL"/>
    <dbReference type="OrthoDB" id="10403186at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="81" mass="9100" checksum="F1A49F2867C8F412" modified="2007-05-15" version="1">MDGVWKLRSVSKFVTTDSLWEMGPHRYSGFIRYNVAGGLVSVCFSPYDKVNHLTIFTGRSSQGLISFVKVDDSPLFHLSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT71</accession>
    <name>A4RT71_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_14187</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416123.1">
        <property type="nucleotide sequence ID" value="XM_001416086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT71"/>
    <dbReference type="STRING" id="436017.A4RT71"/>
    <dbReference type="GeneID" id="5000167"/>
    <dbReference type="Gramene" id="ABO94415">
        <property type="protein sequence ID" value="ABO94415"/>
        <property type="gene ID" value="OSTLU_14187"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14187"/>
    <dbReference type="eggNOG" id="KOG0570">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1464864_0_0_1"/>
    <dbReference type="OMA" id="RTINDVM"/>
    <dbReference type="OrthoDB" id="10585236at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="186" mass="20250" checksum="CA20E8B277E37904" modified="2007-05-15" version="1">MPTSATPYPDPPAFFTLYGAPDVVPPAPPTPPTNAAYASFGANHHTAPWHDPDHGYAASGGFVYPICVDERGKTDAREEMCALTRHATARFVEAMERCVDAPTRAEEATGALHALFNNAHKLINETIRPSQAMTDFEYQIERMIEEKRTSVEALERALERAKAVKANAAEASEDLGVEALKRALEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT98</accession>
    <name>A4RT98_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_35884</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416114.1">
        <property type="nucleotide sequence ID" value="XM_001416077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT98"/>
    <dbReference type="STRING" id="436017.A4RT98"/>
    <dbReference type="GeneID" id="5000169"/>
    <dbReference type="Gramene" id="ABO94406">
        <property type="protein sequence ID" value="ABO94406"/>
        <property type="gene ID" value="OSTLU_35884"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35884"/>
    <dbReference type="eggNOG" id="KOG2604">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011639_1_1_1"/>
    <dbReference type="OMA" id="DEFELWG"/>
    <dbReference type="OrthoDB" id="296793at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009860">
        <property type="term" value="P:pollen tube growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048685">
        <property type="entry name" value="COG3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048320">
        <property type="entry name" value="COG3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007265">
        <property type="entry name" value="COG_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302:SF8">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20671">
        <property type="entry name" value="COG3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04136">
        <property type="entry name" value="COG3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 N-terminal" evidence="10">
        <location>
            <begin position="34"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 C-terminal" evidence="11">
        <location>
            <begin position="220"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="14"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="709" mass="78464" checksum="574937AD911779E1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTE0</accession>
    <name>A4RTE0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Photosystem I reaction center subunit IV, probable</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PsaE</name>
        <name evidence="8" type="ORF">OSTLU_119378</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PsaE family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO94383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416054.1"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4RTE0"/>
    <dbReference type="GeneID" id="5000552"/>
    <dbReference type="Gramene" id="ABO94383">
        <property type="protein sequence ID" value="ABO94383"/>
        <property type="gene ID" value="OSTLU_119378"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119378"/>
    <dbReference type="eggNOG" id="ENOG502S1U2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136462_1_0_1"/>
    <dbReference type="OMA" id="SYWFNDY"/>
    <dbReference type="OrthoDB" id="2161449at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008990">
        <property type="entry name" value="Elect_transpt_acc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003375">
        <property type="entry name" value="PSI_PsaE"/>
    </dbReference>
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        <property type="entry name" value="PRK02749.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT IV A, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHOTOSYSTEM I SUBUNIT IV"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Electron transport accessory proteins"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11744" checksum="3681BE28EF34B9DC" modified="2007-05-15" version="1">MFAMSTMQTAAARAVFVSKPTATKRRTTIVRAEGDAAEPAKAAPPAIGPPRGSKVKILRPESYWFNDYGKVISVDQSGVRYPVVVRFEKVNYAGVSTNNYALDEIEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTQ0</accession>
    <name>A4RTQ0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_14414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            <dbReference type="PubMed" id="17460045"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
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        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="799" mass="86083" checksum="CD5828ED925C283C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTZ4</accession>
    <name>A4RTZ4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTZ4"/>
    <dbReference type="GeneID" id="5000678"/>
    <dbReference type="Gramene" id="ABO94873">
        <property type="protein sequence ID" value="ABO94873"/>
        <property type="gene ID" value="OSTLU_92386"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92386"/>
    <dbReference type="HOGENOM" id="CLU_414701_0_0_1"/>
    <dbReference type="OrthoDB" id="10466049at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="662" mass="73227" checksum="89E2CC02DB96761F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU84</accession>
    <name>A4RU84_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416914.1">
        <property type="nucleotide sequence ID" value="XM_001416877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU84"/>
    <dbReference type="GeneID" id="5001047"/>
    <dbReference type="Gramene" id="ABO95207">
        <property type="protein sequence ID" value="ABO95207"/>
        <property type="gene ID" value="OSTLU_30531"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30531"/>
    <dbReference type="eggNOG" id="ENOG502QRKP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_503772_0_0_1"/>
    <dbReference type="OMA" id="AHWKEDQ"/>
    <dbReference type="OrthoDB" id="2195113at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039604">
        <property type="entry name" value="Bfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027:SF2">
        <property type="entry name" value="LEBERCILIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027">
        <property type="entry name" value="NUCLEAR SEGREGATION PROTEIN BFR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="518" mass="58281" checksum="5FC8DDC7CE181BFC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUA4</accession>
    <name>A4RUA4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_49109</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:20092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416923.1">
        <property type="nucleotide sequence ID" value="XM_001416886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUA4"/>
    <dbReference type="STRING" id="436017.A4RUA4"/>
    <dbReference type="GeneID" id="5001075"/>
    <dbReference type="Gramene" id="ABO95216">
        <property type="protein sequence ID" value="ABO95216"/>
        <property type="gene ID" value="OSTLU_49109"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49109"/>
    <dbReference type="eggNOG" id="KOG0450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004709_1_0_1"/>
    <dbReference type="OMA" id="RDSYCRT"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="17">
        <location>
            <begin position="612"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO95216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="994" mass="112626" checksum="B3A694BD2A625616" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUA7</accession>
    <name>A4RUA7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_92430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NDUFAF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416925.1">
        <property type="nucleotide sequence ID" value="XM_001416888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUA7"/>
    <dbReference type="STRING" id="436017.A4RUA7"/>
    <dbReference type="GeneID" id="5000649"/>
    <dbReference type="Gramene" id="ABO95218">
        <property type="protein sequence ID" value="ABO95218"/>
        <property type="gene ID" value="OSTLU_92430"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92430"/>
    <dbReference type="eggNOG" id="KOG3363">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074390_3_3_1"/>
    <dbReference type="OMA" id="VGCGARI"/>
    <dbReference type="OrthoDB" id="20681at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05125">
        <property type="entry name" value="Mth938_2P1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034095">
        <property type="entry name" value="NDUF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="119" mass="12525" checksum="08231AADB5B5206B" modified="2007-05-15" version="1">MLSLDSYDARGFAIKGAYCVGGVFAYDSLHAAWSPTRVSEITPETLAALEILDPTPDLLIVGTGRTVATLNEETLNYLKELGVAVDASDTVNATSTFNVLVEEGRSVAAALLPAGHVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUI2</accession>
    <name>A4RUI2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="4 15">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_33883</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 15">Cytoplasm</location>
            <location evidence="2 15">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="4 15"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416675.1">
        <property type="nucleotide sequence ID" value="XM_001416638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUI2"/>
    <dbReference type="STRING" id="436017.A4RUI2"/>
    <dbReference type="GeneID" id="5000861"/>
    <dbReference type="Gramene" id="ABO94968">
        <property type="protein sequence ID" value="ABO94968"/>
        <property type="gene ID" value="OSTLU_33883"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33883"/>
    <dbReference type="eggNOG" id="KOG1057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000914_0_0_1"/>
    <dbReference type="OMA" id="IQERWCC"/>
    <dbReference type="OrthoDB" id="18042at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052723">
        <property type="term" value="F:inositol hexakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052843">
        <property type="term" value="F:inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000036">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11950:FF:000002">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VIP1 N-terminal" evidence="18">
        <location>
            <begin position="29"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp fold RimK-type" evidence="17">
        <location>
            <begin position="234"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="875"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1077"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="877"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00071668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO94968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1107" mass="125410" checksum="63BD004F7CECFA93" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUI3</accession>
    <name>A4RUI3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_30630</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416965.1">
        <property type="nucleotide sequence ID" value="XM_001416928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUI3"/>
    <dbReference type="GeneID" id="5000961"/>
    <dbReference type="Gramene" id="ABO95258">
        <property type="protein sequence ID" value="ABO95258"/>
        <property type="gene ID" value="OSTLU_30630"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30630"/>
    <dbReference type="eggNOG" id="ENOG502QS6J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_652854_0_0_1"/>
    <dbReference type="OMA" id="RWTMIAH"/>
    <dbReference type="OrthoDB" id="260091at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF30">
        <property type="entry name" value="DELTA 8-(E)-SPHINGOLIPID DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="13">
        <location>
            <begin position="87"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="417" mass="47277" checksum="723F173A887451CE" modified="2007-05-15" version="1">MTTMTYNETGKWRENLDLAGWAAEMRAIEKEFKAPEHFEEDVKHLKKILTWANLCYFGGLAALTAMPMVGLNMPAWLNGMNPIAAFMMSTAICARWTMVGHHTCHGGYNAAQSTNGEVTGRFHRRKFARGLWRRCTDWMDWMLPEAWDVEHNHLHHYQLGEDADPDLVERNMQELREGNTPMVSRYLQVAGLALVWKWFYYAPNTLKELLARKEREAAKAGNSKPNPFKTGSLPSTVLTVAQGAFKGEFAAVSETIKCFAPYALWSFAALPAIGYAIGGPKAALAWFMTSVLADVMTNVHSFIIIATNHVGDDIYRFETETKPRSDDFYLRAVIGSANFKTGGDANDFMHGWLNYQIEHHMFPDMSMRAYQNMQPRVKAVCEKYGVPYVQESVFTRLGQLVDVMVGKRTMLVWENGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUZ4</accession>
    <name>A4RUZ4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Association with the SNF1 complex (ASC) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_33884</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416754.1">
        <property type="nucleotide sequence ID" value="XM_001416717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUZ4"/>
    <dbReference type="STRING" id="436017.A4RUZ4"/>
    <dbReference type="CAZy" id="CBM48">
        <property type="family name" value="Carbohydrate-Binding Module Family 48"/>
    </dbReference>
    <dbReference type="GeneID" id="5000994"/>
    <dbReference type="Gramene" id="ABO95047">
        <property type="protein sequence ID" value="ABO95047"/>
        <property type="gene ID" value="OSTLU_33884"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33884"/>
    <dbReference type="eggNOG" id="KOG1616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070949_0_0_1"/>
    <dbReference type="OMA" id="HEYKFMV"/>
    <dbReference type="OrthoDB" id="531008at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043554">
        <property type="entry name" value="KINB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46316">
        <property type="entry name" value="SNF1-RELATED PROTEIN KINASE REGULATORY SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46316:SF2">
        <property type="entry name" value="SNF1-RELATED PROTEIN KINASE REGULATORY SUBUNIT BETA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="3">
        <location>
            <begin position="181"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="272" mass="30076" checksum="07478E80026873EE" modified="2007-05-15" version="1">MGGRGCAFVRVRARSRRRTREGNARGARGEESPEREGAARRRAATRTRLTNARANRPQTPTVPIPGGEGGGVNYPAWATTEPALVPVAINWTQGGNSVEVEGSFDNWQSRQTLHRSGNREFAIVMSLRPGVYQYKFIVDGQWKYAPDQPAMYDEIGNVNNVLEVQEYVPEILDSLDAFTAPASPPASYDCAPFNSDDFAKEPPPLPPQLHMTLLNMPMVPDAPNLLPRPQHVVLNHTYCDGTKSESGVQVLGTTHRYRSKYITVVFLKATQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV29</accession>
    <name>A4RV29_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">NEDD8-activating enzyme E1 catalytic subunit</fullName>
            <ecNumber evidence="8 11">6.2.1.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_30829</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.64" evidence="8 11"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416771.1">
        <property type="nucleotide sequence ID" value="XM_001416734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV29"/>
    <dbReference type="STRING" id="436017.A4RV29"/>
    <dbReference type="GeneID" id="5000752"/>
    <dbReference type="Gramene" id="ABO95064">
        <property type="protein sequence ID" value="ABO95064"/>
        <property type="gene ID" value="OSTLU_30829"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30829"/>
    <dbReference type="eggNOG" id="KOG2015">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_13_1_1"/>
    <dbReference type="OMA" id="PYLENYM"/>
    <dbReference type="OrthoDB" id="10255449at2759"/>
    <dbReference type="UniPathway" id="UPA00885"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01488">
        <property type="entry name" value="Uba3_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000001">
        <property type="entry name" value="NEDD8-activating enzyme E1 catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000002">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014929">
        <property type="entry name" value="E2-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030468">
        <property type="entry name" value="Uba3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08825">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01181">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="E2 binding" evidence="12">
        <location>
            <begin position="349"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="433" mass="47881" checksum="DB17C53919383179" modified="2007-05-15" version="1">MSRLDVDFCVDERARWRSIDALLLRRGRFTGPDFEPGEDVARVLREHVRVLVVGAGGLGCELLKGLALSGFTTLDVIDMDTIDVTNLNRQFLFRAEDVGKSKAETAARRVRERVRGCAVNAHHGRIEEKEDGWYKQFDIIALGLDSLEARAYINAVCCGFLDYDEDGNVDPATIKPLVDGGTEGFKGHARVIVPGMTPCFNCTMWLFPPQTTFPLCTLAETPRNAAHCIEYAKLIQWPAERYGETFDADVVEHMTWVYTKALKRAETFGIPGVTYAHTQGVTKNIIPAIPSTNAIIAAACVIETLKMATMCAKGMNNYMMYVGTDGVYSHTVEYERDPSCVVCSPGIAHALNANATLEEFMASIVAAYPDSLAEPSVSFGGKNLYLRGVLESEFAENLNKPMIELMNGRKEGLVVVNDKKMKKTSMRLRLSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV68</accession>
    <name>A4RV68_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MC family transporter: adenylate (Brittle-1 protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_33920</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416789.1">
        <property type="nucleotide sequence ID" value="XM_001416752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV68"/>
    <dbReference type="GeneID" id="5001053"/>
    <dbReference type="Gramene" id="ABO95082">
        <property type="protein sequence ID" value="ABO95082"/>
        <property type="gene ID" value="OSTLU_33920"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33920"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_10_4_1"/>
    <dbReference type="OMA" id="AMATCIK"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="59"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="153"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="271"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="367" mass="39509" checksum="961168A017B6236B" modified="2007-05-15" version="1">MGTAGGAGAGAGGRRWRFLAAAATRAAATKAATGRGATRKANGGGAKPRRREKKLSRKEEAGRRLASGTLATVCVRTVLAPLERVKIEYLLNRSALKLEAMVGGILRTEGALGFWKGNMLNIARTAPFKAINFCAFDTYREIVNRTFPEGSDARKIGLVCAGAGAGMTAVVTCFPMDVLRTRLLTTGGKEKYGSFFACVKMMYRQEGASTFYRGITPALVSMVPNAAVYYSVYDGLKNRRLAQLNAELAATRKKSGSKQAEENSVKNIEQKNMMLYGAVAGVASEASTYPFEVIRRRMQMQSGRSSTAMVFGRKALLSMATTLRSVARESGLKSLYAGLGPSCVQVLPSAALGYYTYEMFKLLLEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="114" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVG5</accession>
    <name>A4RVG5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_37286</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417420.1">
        <property type="nucleotide sequence ID" value="XM_001417383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVG5"/>
    <dbReference type="STRING" id="436017.A4RVG5"/>
    <dbReference type="GeneID" id="5001643"/>
    <dbReference type="Gramene" id="ABO95713">
        <property type="protein sequence ID" value="ABO95713"/>
        <property type="gene ID" value="OSTLU_37286"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37286"/>
    <dbReference type="eggNOG" id="KOG0481">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_7_2_1"/>
    <dbReference type="OMA" id="ITYCKTR"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000347">
        <property type="term" value="C:THO complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000929">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
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        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="306"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO95713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="709" mass="78505" checksum="23587C11EE256F7D" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVL2</accession>
    <name>A4RVL2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_31014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417438.1">
        <property type="nucleotide sequence ID" value="XM_001417401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVL2"/>
    <dbReference type="GeneID" id="5001417"/>
    <dbReference type="Gramene" id="ABO95731">
        <property type="protein sequence ID" value="ABO95731"/>
        <property type="gene ID" value="OSTLU_31014"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31014"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_16_3_1"/>
    <dbReference type="OMA" id="MDWVREQ"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13136">
        <property type="entry name" value="MATE_DinF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF46">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="560" mass="58948" checksum="C603BACB8A3A1B91" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVP8</accession>
    <name>A4RVP8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TATA element modulatory factor 1 TATA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_31052</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417451.1">
        <property type="nucleotide sequence ID" value="XM_001417414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVP8"/>
    <dbReference type="STRING" id="436017.A4RVP8"/>
    <dbReference type="GeneID" id="5001443"/>
    <dbReference type="Gramene" id="ABO95744">
        <property type="protein sequence ID" value="ABO95744"/>
        <property type="gene ID" value="OSTLU_31052"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31052"/>
    <dbReference type="eggNOG" id="KOG4673">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_385154_0_0_1"/>
    <dbReference type="OMA" id="NWESIEF"/>
    <dbReference type="OrthoDB" id="74178at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022092">
        <property type="entry name" value="TMF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022091">
        <property type="entry name" value="TMF_TATA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47347">
        <property type="entry name" value="GOLGIN CANDIDATE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47347:SF2">
        <property type="entry name" value="GOLGIN CANDIDATE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12329">
        <property type="entry name" value="TMF_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12325">
        <property type="entry name" value="TMF_TATA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA element modulatory factor 1 TATA binding" evidence="6">
        <location>
            <begin position="611"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="575"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="251"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="625"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="676"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="71"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="718" mass="78238" checksum="779A0A754FA79A43" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVS5</accession>
    <name>A4RVS5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_14961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417199.1">
        <property type="nucleotide sequence ID" value="XM_001417162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVS5"/>
    <dbReference type="STRING" id="436017.A4RVS5"/>
    <dbReference type="GeneID" id="5001626"/>
    <dbReference type="Gramene" id="ABO95492">
        <property type="protein sequence ID" value="ABO95492"/>
        <property type="gene ID" value="OSTLU_14961"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14961"/>
    <dbReference type="eggNOG" id="KOG0459">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_3_5_1"/>
    <dbReference type="OMA" id="ARFDECT"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03704">
        <property type="entry name" value="eRF3_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04089">
        <property type="entry name" value="eRF3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="406" mass="45486" checksum="26F92A43A44A9718" modified="2007-05-15" version="1">MVDDRVIQKYEREAKEKNRDSWYMAYIMDTSEEERAKGKTVEVGRAHFETEKKRYTVLDAPGHKNYVPNMIAGTAQADVGVLVISARKGEFETGFDKGGQTREHAQLAKTLGVTKLVVVVNKMDDPSVEWAKERYDEIEKKITPFLKQCGYKIDADVTFVPISGLTGANMQKKVGSDVCSWYEGKSFFDTLDDLEPLPRDPNALVRLPVMDKYNEAGAMVMGKIESGTLRMGQTLMLMPNKAGVKVAALFRDEVECTKCLPGENVRLKLTGVQESDIQPGFVLCSVKEPIHICEEIECQLALLELLEHNSVFTKGYKAVIHIHTATEEVEVTKLVSEIDTKLRKPKEGKPKFLKSGSLGNVRLRFAQPVCVEKFADYAQLGRFTLRDEGRTIAIGKVTRLKPKSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXI8</accession>
    <name>A4RXI8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_45682</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417758.1">
        <property type="nucleotide sequence ID" value="XM_001417721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXI8"/>
    <dbReference type="STRING" id="436017.A4RXI8"/>
    <dbReference type="GeneID" id="5001802"/>
    <dbReference type="Gramene" id="ABO96051">
        <property type="protein sequence ID" value="ABO96051"/>
        <property type="gene ID" value="OSTLU_45682"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45682"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_7_28_1"/>
    <dbReference type="OMA" id="QVMQYCW"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04928">
        <property type="entry name" value="ACT_TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001512">
        <property type="entry name" value="Receptor tyrosine-protein kinase erbB-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000180">
        <property type="entry name" value="serine/threonine-protein kinase STY46-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF261">
        <property type="entry name" value="ZINC FINGER CONTAINING PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="122"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="44942" checksum="4755031A77E01CDC" modified="2007-05-15" version="1">MYEIAVSAGNKPRLLSRVSAVLFDVGLNIAEAHVFCTDDGYALDIFIVTGWRQGDAASVQSAVQTALDAADFSDLPASSKGTNAITSSQGSEGRMSNPSGDRSNSDSISIDGGEWELTEKQLVFNEKIASGAFGLLYRGSYCGQEVAIKVLKSNAAEGSGAETLREFAQELNILRRVHHKNIIQLIGALTKQKTMCLVTEFMHGGNLLQYVQEHALKLPELIRYSLGVAMGLDYLHKINIIHRDIKTANLLLDENNAVKIADFGVARIQPTDGSTMTAETGTYRWMAPEVIAHQFYNEKADVYSYGIMVWELVSGGEVPYPGYTPLQAAVGVVQRGLRPTIAPSCHAVIAQVMQYCWLVDPNARPGFEQIISLLKHVDVPREQEGKHGFFDRLRSVSFKSKKKEAQTRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXL5</accession>
    <name>A4RXL5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_31737</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418017.1">
        <property type="nucleotide sequence ID" value="XM_001417980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXL5"/>
    <dbReference type="GeneID" id="5001726"/>
    <dbReference type="Gramene" id="ABO96310">
        <property type="protein sequence ID" value="ABO96310"/>
        <property type="gene ID" value="OSTLU_31737"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31737"/>
    <dbReference type="eggNOG" id="KOG2881">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040186_0_2_1"/>
    <dbReference type="OMA" id="FLYTWYT"/>
    <dbReference type="OrthoDB" id="442680at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="212" mass="21996" checksum="DA35FB5B9DCAF704" modified="2007-05-15" version="1">MTTTAFVEGLSKAFGLIVLSEIGDKTFFIAALMAMKRRRVDVFLGAWSALFAMTALSACAGTMSARALSPVVTKRAATGLFFAFGARGVRDACARGDDDDDELKEVEAELAGRQRNAKKKATTSWAVFAEAFAVTFLAEWGDRSQIATVGLAAQSDVAGVTLGGALGHAVCTGVAVIGGRQLADRAANAERVVTGIGGCLFLLFGVHALLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXM9</accession>
    <name>A4RXM9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_31751</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417783.1">
        <property type="nucleotide sequence ID" value="XM_001417746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXM9"/>
    <dbReference type="STRING" id="436017.A4RXM9"/>
    <dbReference type="GeneID" id="5001873"/>
    <dbReference type="Gramene" id="ABO96076">
        <property type="protein sequence ID" value="ABO96076"/>
        <property type="gene ID" value="OSTLU_31751"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31751"/>
    <dbReference type="eggNOG" id="KOG1029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_429842_0_0_1"/>
    <dbReference type="OMA" id="IGALQQY"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="2"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="215"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="249"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="597"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="439"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="602"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="636"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="684"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="709" mass="76025" checksum="BC7F6386350A2414" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXP3</accession>
    <name>A4RXP3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417792.1">
        <property type="nucleotide sequence ID" value="XM_001417755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXP3"/>
    <dbReference type="GeneID" id="5001737"/>
    <dbReference type="Gramene" id="ABO96085">
        <property type="protein sequence ID" value="ABO96085"/>
        <property type="gene ID" value="OSTLU_31765"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31765"/>
    <dbReference type="HOGENOM" id="CLU_1799698_0_0_1"/>
    <dbReference type="OMA" id="FGRWESG"/>
    <dbReference type="OrthoDB" id="10520227at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="144" mass="15418" checksum="0F2EA7BF92F50737" modified="2007-05-15" version="1">MRDARATTPHDVELGHRAEASTSDAARDDDATTRDGDDDARDATTRDDDDDARDAASPGRAPIGGINEDGYFGDADGAWLPSDRVPLVLRAREAAMAAGEDYGRDVRTFLGAFGWPIAASAFCVFLLIFALEEFGGAKTRRRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXV0</accession>
    <name>A4RXV0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_4049</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418059.1">
        <property type="nucleotide sequence ID" value="XM_001418022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXV0"/>
    <dbReference type="STRING" id="436017.A4RXV0"/>
    <dbReference type="GeneID" id="5002144"/>
    <dbReference type="Gramene" id="ABO96352">
        <property type="protein sequence ID" value="ABO96352"/>
        <property type="gene ID" value="OSTLU_4049"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4049"/>
    <dbReference type="eggNOG" id="KOG0244">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_2_1_1"/>
    <dbReference type="OMA" id="NCARINI"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 7 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="299" mass="32287" checksum="FB3062845565EB1D" modified="2007-05-15" version="1" fragment="single">FTYDGVSRGNEDELAVTYDAHVKEIVGGVLQGYNGSVMAYGQTGSGKTHTMGMGGDNAGAGMARRVFDTIFASIADCEAMTTVKVCTSFIEIYKDEIRDLLLDSEDPEATATATAVTIRENPKEGGVYLNGARIVQVSDVQGCLDVLEEGILRRATAESTMNVRSSRSHAILTINVETKVGDAKATLAKLHLVDLAGSERVTLNESRGQRFKEGVQINMGLLALSNCISALTDANRREWGHVPYRDSKLTRLLQDSLGGNSRTVMFACVSPADTNADETLNTLKYANRARSIRNRVAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY64</accession>
    <name>A4RY64_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS family transporter: phosphate/sugar</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_38823</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418115.1">
        <property type="nucleotide sequence ID" value="XM_001418078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY64"/>
    <dbReference type="GeneID" id="5001941"/>
    <dbReference type="Gramene" id="ABO96408">
        <property type="protein sequence ID" value="ABO96408"/>
        <property type="gene ID" value="OSTLU_38823"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38823"/>
    <dbReference type="eggNOG" id="KOG2532">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_5_11_1"/>
    <dbReference type="OMA" id="DIKHNGP"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000272">
        <property type="entry name" value="Probable anion transporter 6, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF243">
        <property type="entry name" value="ANION TRANSPORTER 6, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="12"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="45850" checksum="43957369DFACD452" modified="2007-05-15" version="1">MTEGGQKKRWGMVFALFIAFVLCNLDKVNMSVAIVPMAESFGWTATQKGLVASAFFWGYSFTQIPGGWLASKYGGKAVLFWGVMLWSFGTLIAPWCAALGMPALLASRFLVGLGEGVAPSAATGVLAKGVPPSQRSKAVTSAFGGLDVGSLLGLLIAPPIIFHLGGWAAVFYLFGALGFFWGAWWFISYMRDSSTDMKEVETTGAKKGLSIPWAAFVRNPQFWALTVAHFTWNYFSYGLLAWLPSFLASAMGVTLSKSSFLSILPYLSTVIVTALIAPLAGELEAKKKLTRTQIRKGSQTLCFGVGAVTLTMIGLIVNATPVAAVTNQTIGMVVGLLSVTFGFAAFIRTGLFCGHQDLSPKYASIMLGVTNTAAAIASTLSTFFTGLFLSMTGGNWAYSLFFPIAALQLVSVFVFLIWKSDPVDFDAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYR6</accession>
    <name>A4RYR6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_41216</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fructosamine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418438.1">
        <property type="nucleotide sequence ID" value="XM_001418401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYR6"/>
    <dbReference type="GeneID" id="5002319"/>
    <dbReference type="Gramene" id="ABO96731">
        <property type="protein sequence ID" value="ABO96731"/>
        <property type="gene ID" value="OSTLU_41216"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41216"/>
    <dbReference type="eggNOG" id="KOG3021">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036517_0_1_1"/>
    <dbReference type="OMA" id="EXHAAKL"/>
    <dbReference type="OrthoDB" id="496295at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="26905" checksum="7773F3416EE03869" modified="2007-05-15" version="1">MFLGEAAGLRALRATNAFVVPEVYGVVGAPEGARGWRSAIAMEYLNFGGRGDQGEFGNALATMHAATPSHEEARNGKFGFERNNTIGETPQPNQWTESWLEFWRDKRLMHMIRLARDPTLTQLAEKVVDKRLADMFSACGEIKPSLLHGDLWSGNIGTVGRKPSVFDPAVYYGHHEADFGMSWCAGFTPAFYEAYHAKIPKAPGFEERAKMYKLYHYLNHYVMFGGGYQRECLSILKELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYS2</accession>
    <name>A4RYS2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_32128</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418442.1">
        <property type="nucleotide sequence ID" value="XM_001418405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYS2"/>
    <dbReference type="STRING" id="436017.A4RYS2"/>
    <dbReference type="GeneID" id="5002307"/>
    <dbReference type="Gramene" id="ABO96735">
        <property type="protein sequence ID" value="ABO96735"/>
        <property type="gene ID" value="OSTLU_32128"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32128"/>
    <dbReference type="eggNOG" id="KOG0315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_5_1"/>
    <dbReference type="OMA" id="VQRNYKH"/>
    <dbReference type="OrthoDB" id="400at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000179">
        <property type="entry name" value="Target of rapamycin complex subunit LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF0">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="74"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="115"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="207"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="249"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="319" mass="34670" checksum="26DCD4DD633093C9" modified="2007-05-15" version="1">MPTPSVVLATAGYDHTVRFWEATRGVCYRTLQYADSQVNKLEITPDKRYLAAAGNPHVRLFEVNASNPQAVTSYDGHTGNVTAVGFEPHGSWMYTGSEDGTVKIWDLRAGGYQREYESRGAVTSVVLHPNGTELMSADQNGNIRVWDLTANACSCELVPEVGTAVQSLTVAGDGSMVVAGNSKGTCYVWKLQPGSKTTAHFEPLHKLNSHNGYVLKCLISPDCRLLATTSSDKTVKLWNLDGFKLERVLEGHQRWVWDCVFSVDAAYLVTASSDTTARLWDCSTGEAIRVYSGHHKAVTCCALNDSAVGDAAEAEISNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ05</accession>
    <name>A4RZ05_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_7571</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418487.1">
        <property type="nucleotide sequence ID" value="XM_001418450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ05"/>
    <dbReference type="STRING" id="436017.A4RZ05"/>
    <dbReference type="GeneID" id="5002501"/>
    <dbReference type="Gramene" id="ABO96780">
        <property type="protein sequence ID" value="ABO96780"/>
        <property type="gene ID" value="OSTLU_7571"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7571"/>
    <dbReference type="eggNOG" id="KOG4209">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_23_6_1"/>
    <dbReference type="OMA" id="FGFQPRR"/>
    <dbReference type="OrthoDB" id="498435at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12306">
        <property type="entry name" value="RRM_II_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF92">
        <property type="entry name" value="POLYADENYLATE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="62"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="144" mass="15729" checksum="E7A63812E6EA640E" modified="2007-05-15" version="1" fragment="single">EQGAGGDEDPEIAAMQRRLKEMEDEAEKLKGEHEKVDDAMAAEEAGKNPEEEAAKKQEADARSVYVGQVDYASTPEDLANAFASAGTVNRVTILHDKFDNPKGFAYVEFLEPDAVHNAILLDGTEIRGRKIKVSAKRTNVPGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ92</accession>
    <name>A4RZ92_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="3">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_15879</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ROX family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418290.1">
        <property type="nucleotide sequence ID" value="XM_001418253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ92"/>
    <dbReference type="GeneID" id="5002532"/>
    <dbReference type="Gramene" id="ABO96583">
        <property type="protein sequence ID" value="ABO96583"/>
        <property type="gene ID" value="OSTLU_15879"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15879"/>
    <dbReference type="eggNOG" id="KOG3706">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_529366_0_0_1"/>
    <dbReference type="OMA" id="KHQPLYA"/>
    <dbReference type="OrthoDB" id="425950at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051864">
        <property type="term" value="F:histone H3K36 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032453">
        <property type="term" value="F:histone H3K4 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="5">
        <location>
            <begin position="175"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="515" mass="56726" checksum="21058188123A4E5F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZC0</accession>
    <name>A4RZC0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418548.1">
        <property type="nucleotide sequence ID" value="XM_001418511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZC0"/>
    <dbReference type="GeneID" id="5002185"/>
    <dbReference type="Gramene" id="ABO96841">
        <property type="protein sequence ID" value="ABO96841"/>
        <property type="gene ID" value="OSTLU_32330"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32330"/>
    <dbReference type="HOGENOM" id="CLU_2268306_0_0_1"/>
    <dbReference type="OMA" id="ACRADRM"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="103" mass="11192" checksum="F6574419D9F04C6A" modified="2007-05-15" version="1">MTCDRDLLESLATDETSAAVEALARALVSDGDANEEGEGEGEDGDDDLRRAYERARGKMAARVAALTEAHAANRADRIKLLTNLVTASRMESWQNQSSLPNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZR1</accession>
    <name>A4RZR1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_35481</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418840.1">
        <property type="nucleotide sequence ID" value="XM_001418803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZR1"/>
    <dbReference type="STRING" id="436017.A4RZR1"/>
    <dbReference type="MEROPS" id="M67.A11"/>
    <dbReference type="GeneID" id="5002670"/>
    <dbReference type="Gramene" id="ABO97133">
        <property type="protein sequence ID" value="ABO97133"/>
        <property type="gene ID" value="OSTLU_35481"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35481"/>
    <dbReference type="eggNOG" id="KOG1555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052991_0_1_1"/>
    <dbReference type="OMA" id="KTGRHEM"/>
    <dbReference type="OrthoDB" id="527244at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="29"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="232"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="307" mass="33986" checksum="414C29C0D5EACF50" modified="2007-05-15" version="1">MQRLMQSGGMPGAMPGAGDAAQVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGQFVDEYTVTVVDVFAMPQSGTGVSVEAVDPVFQTKMLDMLKQTGREEMVVGWYHSHPGFGCWLSGVDINTQQSFEQLNPRLVAVVIDPVQSVRGKVVIDAFRLINPQTIMLGQEPRQTTSNLGHLNKPSISALIHGLNRHYYSIGISYAKSVLEEKMLLNLNKSKWSAGLKVNKFDEQEKQNENVVLELKELATKYEKAVVEEDKLTAQELVVKNVGRQDPKKHLSENVQKLMADNIVQTLGVMLDTICF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZT2</accession>
    <name>A4RZT2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CHR3516</name>
        <name evidence="7" type="ORF">OSTLU_32497</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418854.1">
        <property type="nucleotide sequence ID" value="XM_001418817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZT2"/>
    <dbReference type="STRING" id="436017.A4RZT2"/>
    <dbReference type="GeneID" id="5003056"/>
    <dbReference type="Gramene" id="ABO97147">
        <property type="protein sequence ID" value="ABO97147"/>
        <property type="gene ID" value="OSTLU_32497"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32497"/>
    <dbReference type="eggNOG" id="KOG0383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_740540_0_0_1"/>
    <dbReference type="OMA" id="TVQQHEW"/>
    <dbReference type="OrthoDB" id="10676798at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF13">
        <property type="entry name" value="HELICASE PROTEIN MOM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="6">
        <location>
            <begin position="7"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="SNF2 N-terminal" evidence="5">
        <location>
            <begin position="72"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="42390" checksum="C020908DE5A7E2CC" modified="2007-05-15" version="1">MPPNTRLLVKWWGLPYADCTWETIDGHDDFDMLLERYTQFDHESLKRPYSVPPSLANVDESNKPSKGVQCVARWLLATWFEKEGVCFVDNSPLCKHAEVAANFIADRKRQYDEHGPSLIIVAESELEHWSREFSRIAPDVNVVEYGGSATCRATVQQHEWSFVGAFPRATNGVSTPRFNVLITTHSTVVLDIVLLRQVRWESVIMVENAQKFTAETSSLLSRLGSLHANHRVLMFRAADFSDLHVTLNILEFLKRAPTSMRNLEARLLNLSQEEACMQTAALLAVLTMDYQFCEAALRNKQALAEADACMGTLHTARLLELSEIVLASKVAKESDRRSVFPACFDYTSTQYLGLLHQLQALHDMYRPLVSAEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0B8</accession>
    <name>A4S0B8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">OSTLU_12730</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>2 ATP + H(+) = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34935"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:34936"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>tRNA(Gly) + glycine + ATP = glycyl-tRNA(Gly) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:16014"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Axon</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="5"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418945.1">
        <property type="nucleotide sequence ID" value="XM_001418908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0B8"/>
    <dbReference type="STRING" id="436017.A4S0B8"/>
    <dbReference type="GeneID" id="5002732"/>
    <dbReference type="Gramene" id="ABO97238">
        <property type="protein sequence ID" value="ABO97238"/>
        <property type="gene ID" value="OSTLU_12730"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12730"/>
    <dbReference type="eggNOG" id="KOG2298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015515_1_0_1"/>
    <dbReference type="OMA" id="MEMQYFV"/>
    <dbReference type="OrthoDB" id="57698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00858">
        <property type="entry name" value="GlyRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.230:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.200:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000004">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000158">
        <property type="entry name" value="Glycyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000010">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="20">
        <location>
            <begin position="3"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="19">
        <location>
            <begin position="92"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="4"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ABO97238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="677" mass="75001" checksum="818C72A675F1BE4E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0F7</accession>
    <name>A4S0F7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_8062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418737.1">
        <property type="nucleotide sequence ID" value="XM_001418700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0F7"/>
    <dbReference type="STRING" id="436017.A4S0F7"/>
    <dbReference type="GeneID" id="5002945"/>
    <dbReference type="Gramene" id="ABO97030">
        <property type="protein sequence ID" value="ABO97030"/>
        <property type="gene ID" value="OSTLU_8062"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8062"/>
    <dbReference type="eggNOG" id="ENOG502QUZU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089475_2_0_1"/>
    <dbReference type="OMA" id="RAPNQNS"/>
    <dbReference type="OrthoDB" id="2015319at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043024">
        <property type="term" value="F:ribosomal small subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="RIBOSOME-BINDING FACTOR A, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515:SF1">
        <property type="entry name" value="RIBOSOME-BINDING FACTOR A, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="Ribosome-binding factor A, RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="19795" checksum="B154F1C81EC355F3" modified="2007-05-15" version="1" fragment="single">VVAMAHPRRVQKVQQQMRREISSMMQSDKNLRAMISPEERMGVDHMLSVMATVADVEVSNDLQVVKVYVSILGDERGKNNAIKGMKRMEQYVRRKIGRRMSLRLTPEIRFIYDDSFERGQKVSALLDEIRLENRNKTAKKYGKDALMSVEDVIAERGEVEDEDESEWGMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0F9</accession>
    <name>A4S0F9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_35638</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418738.1">
        <property type="nucleotide sequence ID" value="XM_001418701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0F9"/>
    <dbReference type="STRING" id="436017.A4S0F9"/>
    <dbReference type="GeneID" id="5002876"/>
    <dbReference type="Gramene" id="ABO97031">
        <property type="protein sequence ID" value="ABO97031"/>
        <property type="gene ID" value="OSTLU_35638"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35638"/>
    <dbReference type="eggNOG" id="KOG0354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002513_3_2_1"/>
    <dbReference type="OMA" id="IFYEPVP"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18033">
        <property type="entry name" value="DEXDc_FANCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000861">
        <property type="entry name" value="Fanconi anemia, complementation group M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044749">
        <property type="entry name" value="FANCM_DEXDc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="24"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="356"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO97031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="551" mass="61779" checksum="333F74E2FC398C79" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0T7</accession>
    <name>A4S0T7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419036.1">
        <property type="nucleotide sequence ID" value="XM_001418999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0T7"/>
    <dbReference type="GeneID" id="5002715"/>
    <dbReference type="Gramene" id="ABO97329">
        <property type="protein sequence ID" value="ABO97329"/>
        <property type="gene ID" value="OSTLU_32860"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32860"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_574146_0_0_1"/>
    <dbReference type="OMA" id="SYAMKVQ"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF103">
        <property type="entry name" value="N-METHYLTRANSFERASE DOMAIN AND SET DOMAIN CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="52271" checksum="FDEA1CE904F99437" modified="2007-05-15" version="1">MRALADAIAGSAIGEDGRRAAEIALETLKMEATRALSGLAGAASTTNAARDDACDEMFLWATQRGAMFKFVANVSEGGMREARASAAVDAGDAAARVPWDALLGVEQAVLSSSAPICEVLKQLTAMGDQIIMTIWLAAAMSGQDSRLYEAWAPTLRALPRAPCTALAWDVDTMRLVMDHDQVERLIDYQRKVRVQYDALFPALCEQVPEAFPASVFGDYSRFALAYDIWTSYAMKVQDPQTLQIYEVIVPGVFLCNHALYAHSVRYTSLERGTRAFRLELARGARPGDAITISYGRLDNADLMAYYGFTLPSNPYDRVVLSSLASQANEEQTAALARASEMCGVDLTELPACIALDGSLDRVLTQMRIMSAPQRFMEWCERIDGYHPYTVVDGELEYKVLCELRSHLCHLVAERQASEGSLSHRLSTVHHESTHSVANATRWYLSGQIGIMQSALARVDVLLASYGSGKRSRDEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0V6</accession>
    <name>A4S0V6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">VTC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_32880</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419043.1">
        <property type="nucleotide sequence ID" value="XM_001419006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0V6"/>
    <dbReference type="STRING" id="436017.A4S0V6"/>
    <dbReference type="GeneID" id="5003077"/>
    <dbReference type="Gramene" id="ABO97336">
        <property type="protein sequence ID" value="ABO97336"/>
        <property type="gene ID" value="OSTLU_32880"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32880"/>
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    <dbReference type="GO" id="GO:0006799">
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    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
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        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="577"/>
            <end position="602"/>
        </location>
    </feature>
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        <location>
            <begin position="120"/>
            <end position="373"/>
        </location>
    </feature>
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        <location>
            <begin position="479"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09359"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO97336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="614" mass="68802" checksum="48E6E89A3FF69030" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S128</accession>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="256"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="582" mass="62531" checksum="88BF0BAC3214C7D8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S184</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_1910174_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="14547" checksum="3E152023CB986AAC" modified="2007-05-15" version="1">MAIVSVYSAQPTFVKSCLGSSQPKGSANKLPSSAIPNSDRVTNIDGTTASHLYEVMNTNGEESAKKKTTKFIKWMKAKGIELETIRSISATAFTHASIRPSISNALRSEMCPRRRRSSMMAIIFDAQHPTRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1M8</accession>
    <name>A4S1M8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_88051</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419392.1">
        <property type="nucleotide sequence ID" value="XM_001419355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1M8"/>
    <dbReference type="STRING" id="436017.A4S1M8"/>
    <dbReference type="GeneID" id="5003230"/>
    <dbReference type="Gramene" id="ABO97685">
        <property type="protein sequence ID" value="ABO97685"/>
        <property type="gene ID" value="OSTLU_88051"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88051"/>
    <dbReference type="eggNOG" id="KOG0116">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026954_1_0_1"/>
    <dbReference type="OMA" id="HQSPQMV"/>
    <dbReference type="OrthoDB" id="339151at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000003">
        <property type="entry name" value="Nuclear transport factor 2 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="5">
        <location>
            <begin position="13"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="265"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="350"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="356"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="41017" checksum="13859912F29F5766" modified="2007-05-15" version="1">MAPRAPTPAAEVVGNSFVNQFYTILHTSPAVLYRFYTNDSTLIVSGEHGAASDAPTTYRTQRDIHNKVVSMRYDETQADVKSIDASHTLGGGVLVQVTGALRRKGDDFARNFVQSFLLAPQENGFFVLNDIVRYLDKVDTSGEKAPKEAKTSAKQQDVKGESKTKAAEVKSTKKESGDNKAKGDSKSTEDEDAGEVDPSKPRTYAMMAASAAAAAAAAKPTAATAKPTAATAATISPMTSPSATSPSSKSPDKAEQTVAATKPGCGIFIKNIFIESTVEDLEREFSKFGVVLGGAKGINLKAPKLSHETKFAFIDFDEPASAQAALEATIELHGKILVVEMKKASVVNAKGVGANGKKESKGREGGVERKGSAKNGRQPKKTEGAGSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1P5</accession>
    <name>A4S1P5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IISP family transporter: preprotein translocase SecY subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419403.1">
        <property type="nucleotide sequence ID" value="XM_001419366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1P5"/>
    <dbReference type="STRING" id="436017.A4S1P5"/>
    <dbReference type="GeneID" id="5003184"/>
    <dbReference type="Gramene" id="ABO97696">
        <property type="protein sequence ID" value="ABO97696"/>
        <property type="gene ID" value="OSTLU_33175"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33175"/>
    <dbReference type="eggNOG" id="ENOG502QPS8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030313_3_1_1"/>
    <dbReference type="OMA" id="MSICGGY"/>
    <dbReference type="OrthoDB" id="1903502at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00303">
        <property type="entry name" value="SECYTRNLCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="421" mass="45206" checksum="C18160B542964D7B" modified="2007-05-15" version="1">MVFVRAGLLLPSRFYASTGGYESPFSMSTLMSTFAGSGGAALDAMANALGGDKTAAVTQGANWLADSMSAGGGVPWFHIGIGPFIGASIAMSVVVAFSPDLQRMRKDEMGRETIEWWTRLMTLAIAVIQSVIEARTLKVYSLVGTGLGYYLAVVPMFITGALAITWVADEITDYGLGQGSSVIITMSICGGYFAALKALLPKIMTDFSFATALPAFAFFGVLMLGTVLLEQGTAKVPLQYFQGPSGSAGLPKAFKEDEGDHIPFKINPTNMQPVIFSMFLLSALQWLPFGFLSWINGQSVGYFVLLFILVFAGTYVDLQNTPQDISEYIMKIGARVPGIRPGTKTVEFFSRVQAGARFFGGILLATIATICSLTDLWMSKTTGQSIGLTSMLIVVSTVIAVKRQIQAMSQMPKMDEVLQTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S211</accession>
    <name>A4S211_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_8045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419458.1">
        <property type="nucleotide sequence ID" value="XM_001419421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S211"/>
    <dbReference type="STRING" id="436017.A4S211"/>
    <dbReference type="GeneID" id="5003321"/>
    <dbReference type="Gramene" id="ABO97751">
        <property type="protein sequence ID" value="ABO97751"/>
        <property type="gene ID" value="OSTLU_8045"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8045"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_45_2_1"/>
    <dbReference type="OMA" id="MECFINV"/>
    <dbReference type="OrthoDB" id="509238at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="125" mass="13069" checksum="8A5039E4055C01D7" modified="2007-05-15" version="1" fragment="single">DGETALHLAALYGKVAYVEVLLRRGADPLATDESLGTPLHDACASGHADVARALCDAARDAGTLATLLKKVDEDQETPLHHAARGEHAEVVKYLIELGADKSAKSSVGATPSDLVEDDDSVRALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S290</accession>
    <name>A4S290_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase, cyclophilin-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CYN14</name>
        <name evidence="3" type="ORF">OSTLU_16669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419492.1">
        <property type="nucleotide sequence ID" value="XM_001419455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S290"/>
    <dbReference type="STRING" id="436017.A4S290"/>
    <dbReference type="GeneID" id="5003579"/>
    <dbReference type="Gramene" id="ABO97785">
        <property type="protein sequence ID" value="ABO97785"/>
        <property type="gene ID" value="OSTLU_16669"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16669"/>
    <dbReference type="HOGENOM" id="CLU_910275_0_0_1"/>
    <dbReference type="OMA" id="QHDTLKR"/>
    <dbReference type="OrthoDB" id="408413at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044185">
        <property type="entry name" value="CYP26-2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47724">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP26-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47724:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP26-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="67"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="306" mass="32937" checksum="7616538630E7A1F6" modified="2007-05-15" version="1">MTKFEPLAKGERGRDRARPSAAERRSRMETFKRTGAHPELEIDPDDARRAKRLANVARKNASNVKAFVDVEVAGENRGSVVIEVLEEAAPRAARRFAERLEATEGDRDGVSYRDSCEMTTVDDELRVSFGVSGKRVKTTIEVEGELTHAAAGVVGVDRRSGEFCVTTAACESLDESAQVVGRVISGLEILRALTHREKGEKVPTPVRVTACGVVRGGADVSALVGVAARGRAEAAAKARAEAEKIRNESQHDTLKRLRAESAQKGAEMNEIVRSTLGKKLKEAPKKKPGAGMLDSMLGSSSSDSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2C2</accession>
    <name>A4S2C2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419726.1">
        <property type="nucleotide sequence ID" value="XM_001419689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2C2"/>
    <dbReference type="GeneID" id="5003540"/>
    <dbReference type="Gramene" id="ABO98019">
        <property type="protein sequence ID" value="ABO98019"/>
        <property type="gene ID" value="OSTLU_16696"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16696"/>
    <dbReference type="eggNOG" id="ENOG502SXIS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_797747_0_0_1"/>
    <dbReference type="OMA" id="SCKGCYM"/>
    <dbReference type="OrthoDB" id="496232at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="333" mass="37507" checksum="FAF824F5729C0808" modified="2007-05-15" version="1">MTVMQVMMQPFGIMNALRGKISVPISATAALAAALTAPKSTALYSFCGELTMSQSNSRHSRHFAEWWTLLVSSFMMFFSVTCFVLLETGRYEGIRAVFDTKPWQNAAPLLEDSDELTKAESKLMCPFTGQEGSGTCPICHSIVSHNGYYHGDPPILHTVVGDSILEHRLAMQASEIDDKPRLARVQLDNFIKYRGNFLFATISPSCKGCYMKAWCWTVGYRMVWQSTILGFNTMLCSHLFGEEVLLFDLKSMLLCLSMFFSISTVCMLLSLLATAVVFIREHTFMHTAEVPKFVTQDMGVVEVLLRIMADPRARYGVNPSKTYWSWLWTVKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2F8</accession>
    <name>A4S2F8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419525.1">
        <property type="nucleotide sequence ID" value="XM_001419488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2F8"/>
    <dbReference type="GeneID" id="5003743"/>
    <dbReference type="Gramene" id="ABO97818">
        <property type="protein sequence ID" value="ABO97818"/>
        <property type="gene ID" value="OSTLU_33440"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33440"/>
    <dbReference type="HOGENOM" id="CLU_342373_0_0_1"/>
    <dbReference type="OMA" id="HSKRWTE"/>
    <dbReference type="OrthoDB" id="10426314at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="753"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="798"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="676"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="802"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="828" mass="89580" checksum="A9C4578FE175A793" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2G9</accession>
    <name>A4S2G9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419748.1">
        <property type="nucleotide sequence ID" value="XM_001419711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2G9"/>
    <dbReference type="GeneID" id="5003682"/>
    <dbReference type="Gramene" id="ABO98041">
        <property type="protein sequence ID" value="ABO98041"/>
        <property type="gene ID" value="OSTLU_93229"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93229"/>
    <dbReference type="eggNOG" id="ENOG502SUGV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_629129_0_0_1"/>
    <dbReference type="OMA" id="NDCRHYL"/>
    <dbReference type="OrthoDB" id="513772at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="436" mass="48340" checksum="9BB1ED84B51D9030" modified="2007-05-15" version="1">MTHASPTRETREPLFPGARRGKVATSAGLSGKSDDRRRPTARRLGFASEKDKAIDDELEARERSGTKEAEVYCVSRPFQEWGKGIFSALPRGAREALLTAGVAHFMLVYRDLKTGEMRQFDFGPVGGDVHDRWLALAGGKTLRSSEQGARETVYAMTRGRVGRHRARRKSSCVQGEIRDHKVRSLPDGAYLVGTTHLSLDDIRGFNDARDMVYELHVNDCRHYLNDLCYYLTRETAVSSKFVKHGIMKRLEENKGRIWEHHLWLTKALTDVENVENWNKAGRFASATLMFGMGTRFMPFVPAKRFVTWGSGVVAGTSENVPIVREVLSFGGFLVETGRSALSLALDAQNSVTKSIAKGVEAQLLRTRWKLPMPRGAKLTRAKSVEDSSPLKIGLRVSPSSLTLPAVAASATKAVRSVVSNGAIRRLQRQGRVEISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2P5</accession>
    <name>A4S2P5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_6754</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419568.1">
        <property type="nucleotide sequence ID" value="XM_001419531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2P5"/>
    <dbReference type="STRING" id="436017.A4S2P5"/>
    <dbReference type="GeneID" id="5003774"/>
    <dbReference type="Gramene" id="ABO97861">
        <property type="protein sequence ID" value="ABO97861"/>
        <property type="gene ID" value="OSTLU_6754"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6754"/>
    <dbReference type="eggNOG" id="KOG0221">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_8_3_1"/>
    <dbReference type="OrthoDB" id="547493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="5">
        <location>
            <begin position="96"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="209" mass="23151" checksum="E7DAA79B4070EE53" modified="2007-05-15" version="1" fragment="single">LGDVLHSIVDLQESILRELREEILAHASLMRDISRCVSEIDVLLAFADIAVNYNMCRPTLRDDDAFEVAGARHPLYESFIEGEFIGNDVHMPTDRDRVIVLTGPNGSGKTVMMQTIGLITYLAHCGSFVPATRAVIGLTDRIYTAMTALREDAERKTRVPESGFTYALHQVARMINNATRRSLCLLDEFGIQTQSTDGAALLAAIVEHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2Q4</accession>
    <name>A4S2Q4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DMT family transporter: phosphate/phosphoenolpyruvate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_34716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419573.1">
        <property type="nucleotide sequence ID" value="XM_001419536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2Q4"/>
    <dbReference type="GeneID" id="5003571"/>
    <dbReference type="Gramene" id="ABO97866">
        <property type="protein sequence ID" value="ABO97866"/>
        <property type="gene ID" value="OSTLU_34716"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34716"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022332_3_1_1"/>
    <dbReference type="OMA" id="GEIAFQW"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="20"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="329" mass="36014" checksum="93EF11AC91CD8FBB" modified="2007-05-15" version="1">MGAIRQRFSRAHRAQCARAVILSLLWACASSSLIFLNNHLLRERGFSYPMMLCTMGMLSSWLIACALVHTGRVKLKHEAVVTRRWYARHILPIGSLGAVSLGFGNYVYLYLSVSFIQMLKSAVPAVTLVVMTTAGLEKLHGTTLLGVGIVTLGTFIAAYGEVKFSAIGVVMMIVSEFAEAIRMAFYQYVLGNLKFDLIEGLYVMGPAALLFLGLGIVMFELRDFLDNGAWYIPMDSPHHFFAAALLGFGVNYLTLGVIKATSGLTFKVMGQVKNAVVILLAVVIFGNPVTSIQLFGYTLSLVGFFIYQRGKSQQLVAAIRDRDAASAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S335</accession>
    <name>A4S335_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L6, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL6</name>
        <name evidence="5" type="ORF">OSTLU_94758</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419645.1">
        <property type="nucleotide sequence ID" value="XM_001419608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S335"/>
    <dbReference type="STRING" id="436017.A4S335"/>
    <dbReference type="GeneID" id="5003854"/>
    <dbReference type="Gramene" id="ABO97938">
        <property type="protein sequence ID" value="ABO97938"/>
        <property type="gene ID" value="OSTLU_94758"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94758"/>
    <dbReference type="eggNOG" id="KOG1694">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066767_2_1_1"/>
    <dbReference type="OMA" id="GPYEVNG"/>
    <dbReference type="OrthoDB" id="2436667at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13156">
        <property type="entry name" value="KOW_RPL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000915">
        <property type="entry name" value="60S_ribosomal_eL6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041997">
        <property type="entry name" value="Ribosomal_eL6_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01159">
        <property type="entry name" value="Ribosomal_L6e"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="169" mass="18923" checksum="8C626582612AAA23" modified="2007-05-15" version="1">MAKTKKQVKNGQPSFYPADDIKKPLKRTIEHKQTKLRASIAPGQVLILLAGHLKGKRVVFLKQLESGLLLVAGPYGVNGVPAKRVNQRYVIATSEKVDKPAKDRSNKKSEEEFFKVDLAKKELPADYLENNKALDKALGDAIAKTPYLKEYMSTLFTLKSGDKPHEMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S349</accession>
    <name>A4S349_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419856.1">
        <property type="nucleotide sequence ID" value="XM_001419819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S349"/>
    <dbReference type="STRING" id="436017.A4S349"/>
    <dbReference type="GeneID" id="5003861"/>
    <dbReference type="Gramene" id="ABO98149">
        <property type="protein sequence ID" value="ABO98149"/>
        <property type="gene ID" value="OSTLU_25086"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25086"/>
    <dbReference type="eggNOG" id="KOG2855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043466_0_0_1"/>
    <dbReference type="OMA" id="TCAPAFK"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019206">
        <property type="term" value="F:nucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006190">
        <property type="term" value="P:inosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900542">
        <property type="term" value="P:regulation of purine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47826">
        <property type="entry name" value="OS03G0164700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47826:SF1">
        <property type="entry name" value="OS03G0164700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="1">
        <location>
            <begin position="99"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="438" mass="46448" checksum="7245C7D4BEDC8CCD" modified="2007-05-15" version="1">MISTRVAAHAHVERRRACGECAHSGRASSRARAGAREREVRRRVARRASREYDVVALGNLCVDVLLPPGPIPDATSLKTTKTLGELARTAPARESWELGGNCNFLIAASRLGLRASCAGHVGNDEYGKFLIDELALEGIDHVELIPGDDQGVRVSALAETLICFVLSDGAGSHAFCSRYDLGPWPLMRDVSDVSNEAREALRSCRAVFLNGFVFDELKPQAVAQALKLAKGNGAGVFFDPGPRAFTFVDETNPSRMEALRVALENSDVVLATEEELAALTGVRANAPPTDYAAAVFDFPGSAAEWVVVKLGPEGAMVVTRDGQSARVGCPRVKVGDTVGCGDSSAGAYVLGYLRKQADDALDLSEVLQTTATLATHVGSATAMNIGAGRNVAKAETVLELLDAAVDGKTEGVDRGTASRAQAILRESMNESMKQQQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S380</accession>
    <name>A4S380_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_34792</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="10"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419872.1">
        <property type="nucleotide sequence ID" value="XM_001419835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S380"/>
    <dbReference type="STRING" id="436017.A4S380"/>
    <dbReference type="GeneID" id="5003699"/>
    <dbReference type="Gramene" id="ABO98165">
        <property type="protein sequence ID" value="ABO98165"/>
        <property type="gene ID" value="OSTLU_34792"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34792"/>
    <dbReference type="eggNOG" id="KOG1975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020346_0_0_1"/>
    <dbReference type="OMA" id="LITGDCF"/>
    <dbReference type="OrthoDB" id="10248867at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016899">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028762">
        <property type="entry name" value="ABD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10 12" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="14">
        <location>
            <begin position="73"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="82"/>
            <end position="83"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="12">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR028762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR028762-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR028762-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="384" mass="42616" checksum="58E53FCC60AA86DD" modified="2007-05-15" version="1">MVVAGKRRRSGEDAGDAGDVERADAPSTRDGGAADEDTGAVASSTATKDDAARLVAQHYSGRANQTHQERKQSPIYRLRCLNNWVKSNLLQSKIRENDRVMDLACGKGGDLKKYARAKIASYLGVDIALESVRRDAVKRYNAEHAREFPAKFVAGDAFVVDLASVLPEYVRTLDVISCQFAIHYSLSTEERARRALRNVCTMLRPGGYFIGTTVDSNVLVRKLREADGLAFWNPVYEVEFDDAFKSKVFPTNQTDGFGIEYTFTLADAVTKCRECMVPKDVWVSLAAEYGLELVEWRNFHDYVHSQLSGVETRERASALWSQIMGDDSMSMTDEEWEAAYLYTTFVFRKSGSAEAAASAVFNRKPPAAPARIEQDDVLVLEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3J4</accession>
    <name>A4S3J4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CAAX prenyl protease 2/Lysostaphin resistance protein A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420105.1">
        <property type="nucleotide sequence ID" value="XM_001420068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3J4"/>
    <dbReference type="GeneID" id="5004262"/>
    <dbReference type="Gramene" id="ABO98398">
        <property type="protein sequence ID" value="ABO98398"/>
        <property type="gene ID" value="OSTLU_26075"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26075"/>
    <dbReference type="eggNOG" id="ENOG502R2ZW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087412_0_0_1"/>
    <dbReference type="OMA" id="GSAMFTH"/>
    <dbReference type="OrthoDB" id="496858at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080120">
        <property type="term" value="P:CAAX-box protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="2">
        <location>
            <begin position="74"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="186" mass="19890" checksum="A1B82ABBA0E3E405" modified="2007-05-15" version="1">MAVGSQVLTQFADVHPDVIDGVAAFNVDAAALYMIPLLASLSFAVTQSDKYEYLREVRKMFEESVLPAVAPLGVLGILALSCGAGVGEEALFRGFLMPWVDARLEGLGAGADVAAMGSLASTSLVFGALHAITPQYAVWATWASVLFSIESVRDGLGSAMFTHTLYDFLAFLYVIVSWMPDRESDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3L8</accession>
    <name>A4S3L8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_17041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420116.1">
        <property type="nucleotide sequence ID" value="XM_001420079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3L8"/>
    <dbReference type="STRING" id="436017.A4S3L8"/>
    <dbReference type="GeneID" id="5003982"/>
    <dbReference type="Gramene" id="ABO98409">
        <property type="protein sequence ID" value="ABO98409"/>
        <property type="gene ID" value="OSTLU_17041"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17041"/>
    <dbReference type="eggNOG" id="KOG1864">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_687622_0_0_1"/>
    <dbReference type="OMA" id="FERECYV"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="32"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="42799" checksum="B5815FED0A6991E6" modified="2007-05-15" version="1">MWRGVASEGKHMSAWERETARSERRRPARETGGIENLGNSCYIAASLQLLRSMRGFVESVHEVSGDEDGKPLLAALGEFFRSDASELSASGVKREMGRVRDEYGEFDQHDAMEFMTQMLDTIEREMGDDAAHCPSRQNFAWRIEHALSCVSCGERSVMDESMYMLTLQLIIDENESVDALLDRYFIPEKLERKCSCGCLFAISTRQIVSEPKFLLLHLKRFNAVIARGVLRLQKLTASIRLPSKMSLMHAGSAAAEIVVPKSSGDDSDLEHANNASKSSPDTPGVKRHNTRSVAATRPFDLLAVISHHGNTVELGHFVAHIRERKSKAWKTYDDERVTSYVARDELIFNSLQEFERECYVVAYERDDNENLRQGNAQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3R0</accession>
    <name>A4S3R0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420136.1">
        <property type="nucleotide sequence ID" value="XM_001420099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3R0"/>
    <dbReference type="GeneID" id="5004090"/>
    <dbReference type="Gramene" id="ABO98429">
        <property type="protein sequence ID" value="ABO98429"/>
        <property type="gene ID" value="OSTLU_26142"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26142"/>
    <dbReference type="eggNOG" id="ENOG502T0J7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_529365_0_0_1"/>
    <dbReference type="OrthoDB" id="497754at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673051" evidence="2">
        <location>
            <begin position="28"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="515" mass="57496" checksum="7CEB335EC7BB864D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S498</accession>
    <name>A4S498_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420234.1">
        <property type="nucleotide sequence ID" value="XM_001420197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S498"/>
    <dbReference type="STRING" id="436017.A4S498"/>
    <dbReference type="GeneID" id="5004298"/>
    <dbReference type="Gramene" id="ABO98527">
        <property type="protein sequence ID" value="ABO98527"/>
        <property type="gene ID" value="OSTLU_26335"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26335"/>
    <dbReference type="eggNOG" id="KOG0907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_9_2_1"/>
    <dbReference type="OMA" id="RALMKEW"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="43"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="154" mass="16801" checksum="F214323DFEF2A020" modified="2007-05-15" version="1">MAMRCLSSKTTTPTTAFAARRRQTTAKRQLRVRAGEGETDGNVKFANNKPEFEAVSAAAGSGLVAVQISTKTCGPCKMIYPTFVGLSQELPKVTFVKIMGDTDLESRALMKEWGVRVVPLFLLFRNGERVGEWSGAKADILKENVRAACNADEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4B9</accession>
    <name>A4S4B9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_25194</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420405.1">
        <property type="nucleotide sequence ID" value="XM_001420368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4B9"/>
    <dbReference type="STRING" id="436017.A4S4B9"/>
    <dbReference type="GeneID" id="5004282"/>
    <dbReference type="Gramene" id="ABO98698">
        <property type="protein sequence ID" value="ABO98698"/>
        <property type="gene ID" value="OSTLU_25194"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25194"/>
    <dbReference type="eggNOG" id="ENOG502QQZZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003266_0_0_1"/>
    <dbReference type="OMA" id="WHARGAI"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114:SF2">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13558">
        <property type="entry name" value="SbcC_Walker_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="87"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="4">
        <location>
            <begin position="434"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1112"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="811"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1266" mass="135379" checksum="5EFD4DD0D8A3A23F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="117" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4I6</accession>
    <name>A4S4I6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 9">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="1 9">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Lysyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_50879</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>tRNA(Lys) + L-lysine + ATP = L-lysyl-tRNA(Lys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="1 9"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420444.1">
        <property type="nucleotide sequence ID" value="XM_001420407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4I6"/>
    <dbReference type="STRING" id="436017.A4S4I6"/>
    <dbReference type="GeneID" id="5004474"/>
    <dbReference type="Gramene" id="ABO98737">
        <property type="protein sequence ID" value="ABO98737"/>
        <property type="gene ID" value="OSTLU_50879"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50879"/>
    <dbReference type="eggNOG" id="KOG1885">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008255_6_0_1"/>
    <dbReference type="OMA" id="WESTHHA"/>
    <dbReference type="OrthoDB" id="21243at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000067">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001756">
        <property type="entry name" value="PRK00484.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918:SF15">
        <property type="entry name" value="LYSINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918">
        <property type="entry name" value="LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="262"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="607" mass="66564" checksum="BFF978C7153123F3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4L9</accession>
    <name>A4S4L9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NF-kappa-B-activating protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_88591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NKAP family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_88591"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88591"/>
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    <dbReference type="HOGENOM" id="CLU_032439_3_1_1"/>
    <dbReference type="OMA" id="CFTGFIS"/>
    <dbReference type="OrthoDB" id="497902at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="NKAP"/>
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        <property type="entry name" value="NKAP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087">
        <property type="entry name" value="NF-KAPPA B ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087:SF0">
        <property type="entry name" value="NFKB ACTIVATING PROTEIN LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06047">
        <property type="entry name" value="Nkap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="96"/>
            <end position="194"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="204" mass="22986" checksum="F382FDF9CE39A237" modified="2007-05-15" version="1">MPSPDPRGRADERSKRSKRDASTSSSSSRSRSRSRDAADGDQTHRFKQFLKKRHERLESVRRAAERAEREALDAGEALIGPPPPPESFEVDRDAINHGKHLLAGEGEAMGRFAAAGERIPRRGEIGLKTDQIERFENLGYVMSGSRHSRMNAVRMRKEAQVYSAEEKAALAALSKEERAAKERRVLDDMRALVQAQLESRERHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Q6</accession>
    <name>A4S4Q6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA ligase IV</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Polydeoxyribonucleotide synthase [ATP] 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_26493</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420309.1">
        <property type="nucleotide sequence ID" value="XM_001420272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Q6"/>
    <dbReference type="STRING" id="436017.A4S4Q6"/>
    <dbReference type="GeneID" id="5004601"/>
    <dbReference type="Gramene" id="ABO98602">
        <property type="protein sequence ID" value="ABO98602"/>
        <property type="gene ID" value="OSTLU_26493"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26493"/>
    <dbReference type="eggNOG" id="KOG0966">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004844_2_0_1"/>
    <dbReference type="OMA" id="EGIMIKH"/>
    <dbReference type="OrthoDB" id="151490at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07903">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07968">
        <property type="entry name" value="OBF_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF1">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="17">
        <location>
            <begin position="428"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="18">
        <location>
            <begin position="741"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="18">
        <location>
            <begin position="919"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO98602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="994" mass="112295" checksum="7FE77DE6D70931E3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4U5</accession>
    <name>A4S4U5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_25246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_25246"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25246"/>
    <dbReference type="eggNOG" id="KOG0120">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_077792_0_0_1"/>
    <dbReference type="OMA" id="GLDQMHV"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
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        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="245" mass="27203" checksum="C7DD8C245352D7DA" modified="2007-05-15" version="1">MLCELLNDVLKKIVPEACHAVGKLPPVLSIVMDSAQKYASLEMRSSALATAALGLDQMHVLGRPLHITRPAGYFDDPDAKRQVLNVEHVLPAPEKLQQVYDYLDARKIEESKSKDEAIERAKKMAVSVSESVAHAAAPTTAEATEYLCLENMVDVKTLLSARERKELRYDIEDECGKCGKVVRVVVPTPSDEEVERKAASRAYVYFARVGSAESAHKVMHGRKFGGRIVQARYIEASEFEAFDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5E1</accession>
    <name>A4S5E1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420759.1">
        <property type="nucleotide sequence ID" value="XM_001420722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5E1"/>
    <dbReference type="GeneID" id="5004828"/>
    <dbReference type="Gramene" id="ABO99052">
        <property type="protein sequence ID" value="ABO99052"/>
        <property type="gene ID" value="OSTLU_26730"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26730"/>
    <dbReference type="HOGENOM" id="CLU_588440_0_0_1"/>
    <dbReference type="OMA" id="SYRYYNV"/>
    <dbReference type="OrthoDB" id="495040at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="423" mass="47138" checksum="798B648CD68A99B7" modified="2007-05-15" version="1">MLTIALAPVSVAHSPAPRRARAVPVARAALSTAPESATPITPDARTRVASIPYKDGSVDKVVAINDAAKQAIKDAKAERFVSIIDPKSEKLQKLLSVVDAGWDKIGVKNKNAGHHTLWPEAFEAGKALLEEAFPEECSPEHGGEVLNGVAFVNEPKYYDRAIDFMQRRTKEDFIMSKYNPLGRLHRDPDAIDYKSPGWMTSGMEKSEEYSYRYYNVWLLRSPRDPTGQAWDKPLVVLLPRDGGAREWTYDVRRPEDNVEDDAKKTAGSQFKETMDKIKANPMSAAPMVMQAFSTKKKEDKFEQQDPNYMTRGSPELQPSDEHVWITAPYMIFDSFDMWHGAGQWMPEDKRDLRNGAADAVAARKDAIKGRVSIELRFRARCKPGSREGVPFSPVSSAFRGGVFTPESVRPSDGAYDLKSGSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5M7</accession>
    <name>A4S5M7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7781 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420636.1">
        <property type="nucleotide sequence ID" value="XM_001420599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5M7"/>
    <dbReference type="GeneID" id="5004665"/>
    <dbReference type="Gramene" id="ABO98929">
        <property type="protein sequence ID" value="ABO98929"/>
        <property type="gene ID" value="OSTLU_93533"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93533"/>
    <dbReference type="eggNOG" id="ENOG502SFH0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1216486_0_0_1"/>
    <dbReference type="OMA" id="FMNDIHE"/>
    <dbReference type="OrthoDB" id="497711at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056683">
        <property type="entry name" value="DUF7781"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25003">
        <property type="entry name" value="DUF7781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7781" evidence="1">
        <location>
            <begin position="69"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="228" mass="26011" checksum="E78920DCE2967780" modified="2007-05-15" version="1">MSDAPPTSDAGAGRARRVGLLEALAGTLARCEERLNEVNDKYTFELCPEYRLKMGKTIGRATRVGMTYDAHARRYRVAVKHAVRGGKDEDEDEDEDEDEATARARPMFWKAMKKIVFDPEEKRVEVFTQRLSCGPLSLRGVGEYDVERSEWGLRWQLQTFHKEKKRLRSAEVKLTERVRGCMRWDVSSAAPEVEGKVGSGEKFTFDVDVGSYHVSVPRLELKIDLDHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5P1</accession>
    <name>A4S5P1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_39123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420804.1">
        <property type="nucleotide sequence ID" value="XM_001420767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5P1"/>
    <dbReference type="STRING" id="436017.A4S5P1"/>
    <dbReference type="GeneID" id="5004763"/>
    <dbReference type="Gramene" id="ABO99097">
        <property type="protein sequence ID" value="ABO99097"/>
        <property type="gene ID" value="OSTLU_39123"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39123"/>
    <dbReference type="eggNOG" id="ENOG502S0TB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072177_0_0_1"/>
    <dbReference type="OrthoDB" id="1926212at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="21642" checksum="276E39842DD221C8" modified="2007-05-15" version="1">MCEGDASASARVLAGRALALEGVYRFRDALRDYDEVLRLCEVSGFAPDPYVLNSRGNVHGSLGNWDKAKDDYESAANLFQGARGFKVGASTTQRLDGAIYAFSNLALAEAQLGNEDKALKQLESLVRRAPNSADVRAACAALYYSAARFEDAEDAWERACSRESGCAKYRDIDYVTRIRRWPPVMVAKLEKFLAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5Z7</accession>
    <name>A4S5Z7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_88845</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420697.1">
        <property type="nucleotide sequence ID" value="XM_001420660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5Z7"/>
    <dbReference type="STRING" id="436017.A4S5Z7"/>
    <dbReference type="GeneID" id="5004716"/>
    <dbReference type="Gramene" id="ABO98990">
        <property type="protein sequence ID" value="ABO98990"/>
        <property type="gene ID" value="OSTLU_88845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88845"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_1_1"/>
    <dbReference type="OMA" id="MEIHPWY"/>
    <dbReference type="OrthoDB" id="497186at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="31"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="295" mass="32238" checksum="3463D51075D0BB9A" modified="2007-05-15" version="1">MGGAKSATVTISPGVEMPTVAFGTFKLRGDACRDAVREALMVGFRAVDTASCYRNEDAVADALKSAPRNVCDETWITTKLAPDEMTSEEATNRAIDGMVARLGRAPDLLLVHWPGRSKAAPESDAHGEARKRTWRCMENALRNHKCRAIGTSNYEIAHMRELLSYCDVPPAVNQIEIHPAYPNTEVRAYCASLVPRVHTVGYSPLGVGELLDHPSVRAFADAIGLAPAPALIRWTLSNDCSVVVKSSSRAHTEENLTALSSTHTDDDTIAHHAAILERAFSSHHKKFCWDPRVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S621</accession>
    <name>A4S621_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cysteine synthase</fullName>
            <ecNumber evidence="9">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">OASTL1</name>
        <name evidence="11" type="ORF">OSTLU_26961</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="9"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420867.1">
        <property type="nucleotide sequence ID" value="XM_001420830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S621"/>
    <dbReference type="STRING" id="436017.A4S621"/>
    <dbReference type="GeneID" id="5004731"/>
    <dbReference type="Gramene" id="ABO99160">
        <property type="protein sequence ID" value="ABO99160"/>
        <property type="gene ID" value="OSTLU_26961"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26961"/>
    <dbReference type="eggNOG" id="KOG1252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_1_0_1"/>
    <dbReference type="OMA" id="NAWIPQQ"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000006">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000130">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="10">
        <location>
            <begin position="2"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="164"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="31876" checksum="BC0F2DA2C0B7CDB8" modified="2007-05-15" version="1">MVYLNKTSEGCGAEIAAKLEIMEPCCSVKDRIGWSMIAAAEEEGKITPGKTTLVEPTSGNTGIGLAFIAAAKGYKLTLTMPASMSLERRILLKAFGANLVLTDPAKGMKGAVQKAEEIAAKTPNSYVLQQFENPANPKVHFETTGPEIWEDTAGQIDIFVAGVGTGGTITGTGRYLKSKNPNIKIVAVEPTESPVLSGGGPGPHKIQGIGAGFIPGILDMDVIDEVVQIASDDAISMAKELALQEGLMVGISSGAAAAAAIQLAKRPENAGKLITTVFPSFGERYLSSALYSTIREEAETMTAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S642</accession>
    <name>A4S642_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_17719</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420880.1">
        <property type="nucleotide sequence ID" value="XM_001420843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S642"/>
    <dbReference type="STRING" id="436017.A4S642"/>
    <dbReference type="GeneID" id="5005056"/>
    <dbReference type="Gramene" id="ABO99173">
        <property type="protein sequence ID" value="ABO99173"/>
        <property type="gene ID" value="OSTLU_17719"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17719"/>
    <dbReference type="eggNOG" id="ENOG502S79Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036860_0_0_1"/>
    <dbReference type="OMA" id="ETRKRWN"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="393"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="456"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="548" mass="58108" checksum="9A09287842C58177" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6A1</accession>
    <name>A4S6A1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421057.1">
        <property type="nucleotide sequence ID" value="XM_001421020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6A1"/>
    <dbReference type="STRING" id="436017.A4S6A1"/>
    <dbReference type="GeneID" id="5005114"/>
    <dbReference type="Gramene" id="ABO99350">
        <property type="protein sequence ID" value="ABO99350"/>
        <property type="gene ID" value="OSTLU_27043"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27043"/>
    <dbReference type="eggNOG" id="ENOG502SEKV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1181607_0_0_1"/>
    <dbReference type="OMA" id="FACLNVR"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="66"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="258" mass="29168" checksum="2CB3837084D84F4B" modified="2007-05-15" version="1">MTARCARDEDDDAFRERVRRRIEDAAAADDDAATPTPTPLERERASTLEDDESVVAFVLEKHAAKDYFACLNVRRPDCDDLGRAVWDVGDAELNRAFRKASLRVHPDKNRAADARKAFDAIGETQKMFKDPVRRAEVLRAAAERAFKEKCKRDPEAMRARAKAQEKVDAETYADEMRKQREDAAKKRAAEAKARSAQANRRKRRAESDEEEDALTAMAKSLEAEEEAKKTQNVVGGNGDDDDFAGVVRRKSSKKRFMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6B2</accession>
    <name>A4S6B2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_41712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420913.1">
        <property type="nucleotide sequence ID" value="XM_001420876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6B2"/>
    <dbReference type="STRING" id="436017.A4S6B2"/>
    <dbReference type="GeneID" id="5005021"/>
    <dbReference type="Gramene" id="ABO99206">
        <property type="protein sequence ID" value="ABO99206"/>
        <property type="gene ID" value="OSTLU_41712"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41712"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_59_0_1"/>
    <dbReference type="OMA" id="EARFTIW"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="444" mass="50250" checksum="2376AAC26852EA7F" modified="2007-05-15" version="1">MPREVTRVGAYALKHALGRGAFGWVKLAVQDETGAKAAIKILDRENLQRLDEQDQVKAEVKAMADLTHPCIVDLKEVLSDEQSVFMVMQYCPGGEVYDRVRAKGSFGEAEARRHFQRLIQGVDFCHKKRIYHRDLKPENLFFDERGELCIGDFGLAALRADAEDTNLRTICGTPHFAAPETRSDGYDGGPADVWSCGCILYFMLTAKYPFDGKNFVQLQLMVQKTEPYFPSGSMSRSCEKLIKGMLVKDPTKRMTLDQVMKNSWFKVDFVPVKVEHNANTNRFFDEEDPTLAQFMTPDDKLVVKKSSMMSTNESKLRPIKQLNAFELINIAAFDVANIFDEDENTVSNATRFVSKVEIDRVQAAIIERATALGSVAHRQTQARVVFECQSTGQVVTMRTYQVIPGVCVYDFSRDEGGREHFHTWFANLRDENHEVGKLILSEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6E4</accession>
    <name>A4S6E4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="2">2.7.11.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_41728</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="2"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421079.1">
        <property type="nucleotide sequence ID" value="XM_001421042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6E4"/>
    <dbReference type="STRING" id="436017.A4S6E4"/>
    <dbReference type="GeneID" id="5005135"/>
    <dbReference type="Gramene" id="ABO99372">
        <property type="protein sequence ID" value="ABO99372"/>
        <property type="gene ID" value="OSTLU_41728"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41728"/>
    <dbReference type="eggNOG" id="KOG0198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="YLTRECK"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06632">
        <property type="entry name" value="STKc_MEKK1_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="14"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="301"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="323" mass="36010" checksum="D45AC606D064388E" modified="2007-05-15" version="1">MCHTSLAPTKPRRWTKGDNLGEGSYGSVWLALNGDTGELFALKEVRVGSSDKHRDESIEQLEQEVDVLSRLVHPNIVRYIGITRQETALYIFLEYVPGGSIASLVQRFGKFEENVIRVYTRQILIGLAYLHSQRVVHRDIKGANILVEKSGRIKLADFGMAKVLERVSIGKSFKGSACWMAPEVIRQQNIGFEADIWSVGCTVYEMSTGSPPWSECSTQVQIIFKIASSNEIPDIPEDLSPEGQDFLRLCLQRDAEMRPEAVALLDEPFVLDAHRSSDHTQNIPGLQYDTWASSSAVDDGSILSSEADPSSRVNSSRHVAWEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6J3</accession>
    <name>A4S6J3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93610</name>
        <name evidence="3" type="ORF">OSTLU_94169</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420954.1">
        <property type="nucleotide sequence ID" value="XM_001420917.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422940.1">
        <property type="nucleotide sequence ID" value="XM_001422903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6J3"/>
    <dbReference type="GeneID" id="5005160"/>
    <dbReference type="GeneID" id="5006910"/>
    <dbReference type="Gramene" id="ABO99247">
        <property type="protein sequence ID" value="ABO99247"/>
        <property type="gene ID" value="OSTLU_93610"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01299">
        <property type="protein sequence ID" value="ABP01299"/>
        <property type="gene ID" value="OSTLU_94169"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93610"/>
    <dbReference type="KEGG" id="olu:OSTLU_94169"/>
    <dbReference type="HOGENOM" id="CLU_1838495_0_0_1"/>
    <dbReference type="OMA" id="KFMITSA"/>
    <dbReference type="OrthoDB" id="498677at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="140" mass="15176" checksum="42414DD9CD953733" modified="2007-05-15" version="1">MSSAKVQFMITNAMRAILVDDLDYLDAEVDVMRPEIAAQLIETRTKRPFGDRPMPEAWKRGGNMPQRRGGGALSNNLVKLFLAGVCCLGAAVMSGRVSVGTLLGGAPLGRKPLKKLSSEMKSTKKRKSSSKKRRKKTAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6K1</accession>
    <name>A4S6K1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_10386</name>
        <name evidence="3" type="ORF">OSTLU_7373</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420958.1">
        <property type="nucleotide sequence ID" value="XM_001420921.2"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422936.1">
        <property type="nucleotide sequence ID" value="XM_001422899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6K1"/>
    <dbReference type="STRING" id="436017.A4S6K1"/>
    <dbReference type="GeneID" id="5004963"/>
    <dbReference type="GeneID" id="5006906"/>
    <dbReference type="Gramene" id="ABO99251">
        <property type="protein sequence ID" value="ABO99251"/>
        <property type="gene ID" value="OSTLU_10386"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01295">
        <property type="protein sequence ID" value="ABP01295"/>
        <property type="gene ID" value="OSTLU_7373"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10386"/>
    <dbReference type="KEGG" id="olu:OSTLU_7373"/>
    <dbReference type="eggNOG" id="ENOG502S9JW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101804_0_0_1"/>
    <dbReference type="OrthoDB" id="497345at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="198" mass="22059" checksum="C0BD1DB8AB6260C3" modified="2007-05-15" version="1" fragment="single">VLVLTQRDYERVLPIAATGEQYGYFWGDNDTAFQRVGLSLLTTVLTANAAPALAVPASTFFLWAPVALAARRNSKVRSAKYAGLWRARVISVEPVETRGTSSVDWMFNLVVGDRSGARVPLKVPLKAEYADINVGDDVELIVTSDDPYFYTFQAVREAYFPFLNVWVGEYPFLDRRGMVSVSDRLAGEEEARRARARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6P2</accession>
    <name>A4S6P2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27190</name>
        <name evidence="5" type="ORF">OSTLU_94153</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421123.1">
        <property type="nucleotide sequence ID" value="XM_001421086.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422831.1">
        <property type="nucleotide sequence ID" value="XM_001422794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6P2"/>
    <dbReference type="GeneID" id="5005189"/>
    <dbReference type="GeneID" id="5006970"/>
    <dbReference type="Gramene" id="ABO99416">
        <property type="protein sequence ID" value="ABO99416"/>
        <property type="gene ID" value="OSTLU_27190"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01190">
        <property type="protein sequence ID" value="ABP01190"/>
        <property type="gene ID" value="OSTLU_94153"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27190"/>
    <dbReference type="KEGG" id="olu:OSTLU_94153"/>
    <dbReference type="eggNOG" id="ENOG502S1U3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092630_0_0_1"/>
    <dbReference type="OMA" id="TMLWQFR"/>
    <dbReference type="OrthoDB" id="447842at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43046">
        <property type="entry name" value="GDP-MANNOSE MANNOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43046:SF13">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="38"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP01190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="214" mass="24258" checksum="ED2997CA65D7E19B" modified="2007-05-15" version="1">MPAPTRPPTRHHHFETGTYKPSGLFLPDDEYGRALDALVKGCVDCLLTNEKGEVLLGLRKHEPAKGTWWYIGGRMRTGETVEETARRHAKRDIGIEIDTERFRFVTTSTMNWEFRVQEPAGNGTCDINVVLAATLTEEEIARKTMCADEYLDQKFWSVEDILAVTDEKVILPPIHISAKKMVWSEREDAMYAAVARGADDAEIARLARRAYEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6P3</accession>
    <name>A4S6P3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_88990</name>
        <name evidence="5" type="ORF">OSTLU_89854</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420983.1">
        <property type="nucleotide sequence ID" value="XM_001420946.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422911.1">
        <property type="nucleotide sequence ID" value="XM_001422874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6P3"/>
    <dbReference type="GeneID" id="5004980"/>
    <dbReference type="GeneID" id="5006889"/>
    <dbReference type="Gramene" id="ABO99276">
        <property type="protein sequence ID" value="ABO99276"/>
        <property type="gene ID" value="OSTLU_88990"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01270">
        <property type="protein sequence ID" value="ABP01270"/>
        <property type="gene ID" value="OSTLU_89854"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88990"/>
    <dbReference type="KEGG" id="olu:OSTLU_89854"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_2_1"/>
    <dbReference type="OMA" id="VKSCEAY"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP01270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="363" mass="39054" checksum="C942063413E83AAC" modified="2007-05-15" version="1" fragment="single">VSRAKWIKSSLRRDVASRARSRPTVVDVVQRSAMGIRAACAVDMRGKIAVVTGANTGIGLQTARLLADAGARVVMACRSIDRARAALEYASNGGANDVAVMALDLSDAASVRAFAEKFGKEYEKLDVLVNNAGLNGASGYSGPKTTKQGYDICMGVNYLGHFMLTSLLLPQLMKSDGARVVALSSVTTWFGSNKYQYYYKGASKTKGNYGSSKLACLAMTVELQRRLDAAYPDNKIVCAAADPGFVASNIWRDYNPVLRKIMSILALTPAQGAMTSVNAASLPSITKATLYMPFKIKMSKLFKMHKSATYMFGMPLLSKAFAGFGADAMAPRAKNAESNAKLWDLSIEFCKENGVKSCEAYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4S721</accession>
    <name>A4S721_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_27323</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 14">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421196.1">
        <property type="nucleotide sequence ID" value="XM_001421159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S721"/>
    <dbReference type="STRING" id="436017.A4S721"/>
    <dbReference type="GeneID" id="5005383"/>
    <dbReference type="Gramene" id="ABO99489">
        <property type="protein sequence ID" value="ABO99489"/>
        <property type="gene ID" value="OSTLU_27323"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27323"/>
    <dbReference type="eggNOG" id="KOG0374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004962_0_0_1"/>
    <dbReference type="OMA" id="APIQICG"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000026">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="11">
        <location>
            <begin position="119"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="36545" checksum="36ED1CB8B909737D" modified="2007-05-15" version="1">MTTTLDVDSVIERLLSVRGQPNNRTVQLAEGEIRALCAAAREIFLAQPCLLELEAPLKICGDVHGQYSDLLRLFEYGGFPPEANYLFLGDYVDRGKQGLEVICLLLAYKVKYPENFFLLRGNHECNSISRIYGFYDECKRRYNIKLWRVFCDVFNCLPFAAIVDEKIFCIHGGPSPELKDLQQIVQIKRPTDIPDMGMLCDFLWSDPDADIQGWGENDRGVSYTYGTDVVGDFLHKFDFDLVVRAHQVVENGYEFFGKRQLVTVFSAPNYCGEFDNAGAMMTVDENLMCSFQILKPAERKLMGGFGSMMGARPSTPPRTGGAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7T8</accession>
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        </recommendedName>
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        <name evidence="3" type="ORF">OSTLU_47582</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="component" value="Chromosome 14"/>
    </dbReference>
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        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:vesicle-mediated transport"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
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    </dbReference>
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    </dbReference>
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        </location>
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        </location>
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        </location>
    </feature>
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        <location>
            <position position="428"/>
        </location>
    </feature>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="428" mass="46803" checksum="35E75280AC304D2E" modified="2007-05-15" version="1" fragment="single">MSSSPAPAVLTFQTFLEKMRQPSAGALVRDVKTFIASLDDDASTTTTTVDGEDDDDGDDDAILRVARRVQTFLRDTEATFERHPAWRGASMAELDASGEGLEKYVMTKAHAGVFARRREDRARDERLAKRVETLKKIIEPKHLDIGECSASWALAEVELGKMNQFKAPRDKLVCVLNTCRIINNTLTTRQGSDGGADDFLPVLIYVAMRANPGRLESNLKYIQRFRGESRLVSEAAYFFTNLVSAARFLGRCAANDFTNMDVEMFERVMNEDGVLASVDLDEDEEIAETPVEAASAENPPPSTPPPQISVEEMSAALSALEGGDTSTTPREIPKNAGGGVGDYATDDDNLHTPTSRAAAPYVPWRTTEDVEAEGATQLTALDVAGNLTLSSDYKFLYAKVEDLTVGDVARLLHDYKGLALQYESLSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7V1</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        </lineage>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7V1"/>
    <dbReference type="GeneID" id="5005234"/>
    <dbReference type="Gramene" id="ABO99809">
        <property type="protein sequence ID" value="ABO99809"/>
        <property type="gene ID" value="OSTLU_18193"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18193"/>
    <dbReference type="HOGENOM" id="CLU_008814_0_0_1"/>
    <dbReference type="OMA" id="GSRKMNV"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
    </feature>
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    </feature>
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        </location>
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            <end position="187"/>
        </location>
    </feature>
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        <location>
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    </feature>
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            <end position="512"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </location>
    </feature>
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            <end position="37"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
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            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="888" mass="98980" checksum="4775B88887C8411B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S830</accession>
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    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <lineage>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421520.1"/>
    </dbReference>
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        <property type="gene ID" value="OSTLU_27707"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27707"/>
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    <dbReference type="OMA" id="THCHSVP"/>
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        <property type="component" value="Chromosome 15"/>
    </dbReference>
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        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="589"/>
            <end position="614"/>
        </location>
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            <end position="183"/>
        </location>
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            <end position="246"/>
        </location>
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            <begin position="259"/>
            <end position="453"/>
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        <location>
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            <end position="870"/>
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            <begin position="129"/>
            <end position="138"/>
        </location>
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            <begin position="165"/>
            <end position="175"/>
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    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99850.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="870" mass="95124" checksum="127DB30B61704609" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8A8</accession>
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            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">OSTLU_27784</name>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
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        <property type="component" value="Chromosome 15"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="521" mass="56264" checksum="B25E7C1B4E82E8FF" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">OSTLU_28021</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="OMA" id="RYELAME"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="282" mass="32901" checksum="CD560D1AE9B3BBF5" modified="2007-05-15" version="1">MVAARRASADEEERRGLVEVELGATTTTADDDEKETILRRLRAMESLVQVLPRKCEALEMENAALRELLDDARRDARRFCGECEIETEVAMERARTAISDARRVMHEQRVRYEDTMAESEREGRHRLAMATLKSKSEYARAKLRASEAVEECERYRAEIERLRDELERLRDERVRDAALPSTTNREDDLSTVSDFGRDSVVHQMRWRLWASELTRNDERSLVRDAEDSLEMFAHLQVQLDELKREKRSATSALEEMNSLLIESRDEVYDLKHALKLDLEEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9G5</accession>
    <name>A4S9G5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001421893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9G5"/>
    <dbReference type="GeneID" id="5005959"/>
    <dbReference type="Gramene" id="ABP00224">
        <property type="protein sequence ID" value="ABP00224"/>
        <property type="gene ID" value="OSTLU_18613"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18613"/>
    <dbReference type="HOGENOM" id="CLU_1162766_0_0_1"/>
    <dbReference type="OrthoDB" id="10463816at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="25487" checksum="7F42C97196204081" modified="2007-05-15" version="1">MAVAQRVSVDEALKRVVSHADVVGAGIMTSRGALVERRGAFSDADARTSCRLVAVASHAIISGSGGGIDDNDDGIEMVRARRGACELVVASDATSSGEHFGALSHDERVSILGEAIIDSGALVFTKSHSGRYTCVDNAFLKAFGFEKSEDVVGLTDDEVIEKILASGKTFHHSYRGESVTDLPRIWKENDDLVQHNNRTMWFKERALLSGGEDTKLHEFVVMKSPFAGGVLGVAVPAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9M4</accession>
    <name>A4S9M4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-splicing endonuclease subunit Sen54 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_18657</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN54 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422092.1">
        <property type="nucleotide sequence ID" value="XM_001422055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9M4"/>
    <dbReference type="STRING" id="436017.A4S9M4"/>
    <dbReference type="GeneID" id="5006150"/>
    <dbReference type="Gramene" id="ABP00409">
        <property type="protein sequence ID" value="ABP00409"/>
        <property type="gene ID" value="OSTLU_18657"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18657"/>
    <dbReference type="HOGENOM" id="CLU_832584_0_0_1"/>
    <dbReference type="OMA" id="GCCWESF"/>
    <dbReference type="OrthoDB" id="514732at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024337">
        <property type="entry name" value="tRNA_splic_suSen54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024336">
        <property type="entry name" value="tRNA_splic_suSen54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12928">
        <property type="entry name" value="tRNA_int_end_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen54 N-terminal" evidence="4">
        <location>
            <begin position="50"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="334" mass="37455" checksum="FA9212C0595AA56A" modified="2007-05-15" version="1">MATEAATRDARGAVFRRGAKATQTPVDGALSEAQKTRRASALASLRAHCDATRGQKSAVMPCAIWRATKRRAEVVRHRGRHFTRFGCARGDGVWLSAEECAFLVETERLALFFSEKDERCASVRAVYRLMARVGVSREAYLAYAHVCRLGYVCRRFGSAWTMEARASDADLVAATEGLGIWKRAREGEDGAVDDDRDAVKRRKIAPSTREIKKTPRQRELQSRRWWFASGAIEHEWIGPEIDAAIEANAKPPYAMTLEYDETPVRVAPTFQVYQPNRNFSKKSPDPVSFYLYVASERPPNGRETRSLIEQANGKPVRVASCRQSTVMMFTLSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9N5</accession>
    <name>A4S9N5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_89498</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422202.1">
        <property type="nucleotide sequence ID" value="XM_001422165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9N5"/>
    <dbReference type="STRING" id="436017.A4S9N5"/>
    <dbReference type="GeneID" id="5006259"/>
    <dbReference type="Gramene" id="ABP00519">
        <property type="protein sequence ID" value="ABP00519"/>
        <property type="gene ID" value="OSTLU_89498"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89498"/>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_736897_0_0_1"/>
    <dbReference type="OMA" id="WGMRSGV"/>
    <dbReference type="OrthoDB" id="538768at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="2"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="53"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="103"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="153"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="203"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="376" mass="37699" checksum="9C52DBE3E9DBC936" modified="2007-05-15" version="1" fragment="single">VQCWGSNGDGQLADGTTIYRLTPVLVSGITTATSVSAGGSMSGSHTCALLADGTVQSWGYNANGQLGDGTTTNRLTPVLVSGITTATSVSAGGGHTCATLADGTVQCWGYNDKGQLGDGTTTHRPTPVLVSGITTATSVSTGGAHTCAMLADGTVQCWGYNLDGRLGDGTKTNRLTPVLVSGITTATSVSAGGSHNCAMLADGTVQCWGVNVNSQLGDGTTTSSNIPVQVSNITTATSVSAGYDFNCATLAGDTVQCWGYNDKGQLGNNATTSSNIPVQVLGITTTTSVSAGGSSGGGGVPGTIVPLRSADTLSDVEIAGIAVGCIAFVIILTLIGLCVRSRRRADDKLRARLGIPTRGAPVAVTPQQPQVIVIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9P8</accession>
    <name>A4S9P8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Large ribosomal subunit protein uL22c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PRPL22</name>
        <name evidence="10" type="ORF">OSTLU_18674</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422105.1">
        <property type="nucleotide sequence ID" value="XM_001422068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9P8"/>
    <dbReference type="STRING" id="436017.A4S9P8"/>
    <dbReference type="GeneID" id="5006265"/>
    <dbReference type="Gramene" id="ABP00422">
        <property type="protein sequence ID" value="ABP00422"/>
        <property type="gene ID" value="OSTLU_18674"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18674"/>
    <dbReference type="eggNOG" id="KOG1711">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083987_3_2_1"/>
    <dbReference type="OMA" id="YVSECYA"/>
    <dbReference type="OrthoDB" id="1840754at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_uL22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_uL22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047867">
        <property type="entry name" value="Ribosomal_uL22_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="101" mass="11522" checksum="86D5035E998AB676" modified="2007-05-15" version="1">MSASKIRRVLDVIRGKSYEECLIMLEFMPYRSCEPILNALFSCASNAKNNMGMNKAKLYVSECYADGGATMKRFRPRAQGRPFSIRKRTASITLKMAERED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9S4</accession>
    <name>A4S9S4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase family 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_89517</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422117.1">
        <property type="nucleotide sequence ID" value="XM_001422080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9S4"/>
    <dbReference type="GeneID" id="5006175"/>
    <dbReference type="KEGG" id="olu:OSTLU_89517"/>
    <dbReference type="HOGENOM" id="CLU_1028154_0_0_1"/>
    <dbReference type="OMA" id="PLMCINA"/>
    <dbReference type="OrthoDB" id="1910256at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="2">
        <location>
            <begin position="77"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="271" mass="29948" checksum="2DA9C06256032CC2" modified="2007-05-15" version="1" fragment="single">LCGGDVPFIWSPFRIFSRSDFDGHHALECDGVRRSDGVLALCASDADFVTERLGAAVRPLVVHPPLRESVLKIARARRGETRRRKYLTCVVRVSEEKEPHRFVELCEELARRGVFDSKALSPVFCANASLCQTSAYAQDLKARFQKCAPSGRVIEHFLSPEELGELFSETILNIHPPTHDAFGMTIVESAAFGAPSVVHHAGAVGASELLQTIGVDVEAPTREFADKIEEILLDARTRVVAENAHSKALEWDEASFGHAVFDFLFSHIRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9Z8</accession>
    <name>A4S9Z8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">MC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_28374</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422154.1">
        <property type="nucleotide sequence ID" value="XM_001422117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9Z8"/>
    <dbReference type="STRING" id="436017.A4S9Z8"/>
    <dbReference type="GeneID" id="5006212"/>
    <dbReference type="Gramene" id="ABP00471">
        <property type="protein sequence ID" value="ABP00471"/>
        <property type="gene ID" value="OSTLU_28374"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28374"/>
    <dbReference type="eggNOG" id="KOG0761">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_0_1_1"/>
    <dbReference type="OMA" id="YWWGYES"/>
    <dbReference type="OrthoDB" id="498385at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="5"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="134"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="249"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="36028" checksum="6FF413BAD02139CC" modified="2007-05-15" version="1">MRDEVTLRTRVVASACAASVAAVVTNPLDVIKTQIQANHAALARINRLNLAPYSAKSCPTTCPTTGSATYMCAPECALPTKTLDAARTLARREGARGFWRGTGGALFVALPAVGIYLPCYDYALRWLIESGGVGENAAPALAGAASRTLAVSACAPLELARTRVLATRRGSPGVYGQSGGRAFVGALRESAGGRGGGMLAGARNAWTGVGPTLARDVPYSAMYWYAVEQFRSILGGDVAGHRRERTTRELAGINFVSGCAAGAAVAALTTPLDVVKTRVQIRDIAPVDFASSTETVPGVSRRGIVGELAHIARTGGVDALFAGWGPRAARAAPTGAIVLVAYEVVKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA90</accession>
    <name>A4SA90_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DMT3503</name>
        <name evidence="9" type="ORF">OSTLU_25785</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422300.1">
        <property type="nucleotide sequence ID" value="XM_001422263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA90"/>
    <dbReference type="GeneID" id="5006400"/>
    <dbReference type="Gramene" id="ABP00617">
        <property type="protein sequence ID" value="ABP00617"/>
        <property type="gene ID" value="OSTLU_25785"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25785"/>
    <dbReference type="eggNOG" id="ENOG502SG13">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_359974_0_0_1"/>
    <dbReference type="OMA" id="ICQCLTT"/>
    <dbReference type="OrthoDB" id="496767at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050750">
        <property type="entry name" value="C5-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039479">
        <property type="entry name" value="Mono-CXXC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047365">
        <property type="entry name" value="Tudor_AtPTM-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098:SF1">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15626">
        <property type="entry name" value="mono-CXXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21743">
        <property type="entry name" value="PTM_DIR17_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Single CXXC unit" evidence="7">
        <location>
            <begin position="612"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="PTM/DIR17-like Tudor" evidence="8">
        <location>
            <begin position="703"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="778" mass="87631" checksum="21F367D1FD4C50CD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAC7</accession>
    <name>A4SAC7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_28523</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422363.1">
        <property type="nucleotide sequence ID" value="XM_001422326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAC7"/>
    <dbReference type="STRING" id="436017.A4SAC7"/>
    <dbReference type="GeneID" id="5006470"/>
    <dbReference type="Gramene" id="ABP00680">
        <property type="protein sequence ID" value="ABP00680"/>
        <property type="gene ID" value="OSTLU_28523"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28523"/>
    <dbReference type="eggNOG" id="KOG1401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_1_5_1"/>
    <dbReference type="OMA" id="WGPLIFG"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000021">
        <property type="entry name" value="Glutamate-1-semialdehyde 2,1-aminomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000012">
        <property type="entry name" value="Glutamate-1-semialdehyde 2,1-aminomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000818">
        <property type="entry name" value="PRK00062.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713:SF3">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABP00680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="469" mass="49769" checksum="EDAC445EBC5023FB" modified="2007-05-15" version="1">MFAATTTLGATKFVVAKTSTSTSSRARRSTPRVRAQSVQAPALNTTRSSEIFKAAQDILPGGVNSPVRAFKSVGGNPIVFERVKDAYAFDVDGNKYVDYVGSWGPAICGHANDRVNEKLKAQIDKGTSFGAPCELENALGEMVIERVPSVEMVRFCNSGTEACLSALRVMRAYTGRDMIIKFEGCYHGHADPFLVKAGSGVITLGLPDSPGVPAAATATTLCATYNNLDEVKALFAANPGKIAGVILEPVVGNSGFIAPDKEFLQGLRETCTKEGAVLCFDEVMTGFRIAKGCAQEYWGVTPDLTTMGKVIGGGMPVGAYGGKREIMDMVAPAGPMYQAGTLSGNPLAMVAGIETLKILGEPGQYEKLDKLTKRLIEGILKAGKDNGHAVCGGHISGMFGFFFTEGPVKNFADAAKSDTEKFGRWHRAMLEEGVYLAPSQYEAGFMSLAHTEADIDATIAAAQRAMARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAK4</accession>
    <name>A4SAK4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TRP-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TPR7</name>
        <name evidence="2" type="ORF">OSTLU_18903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422447.1">
        <property type="nucleotide sequence ID" value="XM_001422410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAK4"/>
    <dbReference type="STRING" id="436017.A4SAK4"/>
    <dbReference type="GeneID" id="5006504"/>
    <dbReference type="Gramene" id="ABP00764">
        <property type="protein sequence ID" value="ABP00764"/>
        <property type="gene ID" value="OSTLU_18903"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18903"/>
    <dbReference type="eggNOG" id="KOG0543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1071146_0_0_1"/>
    <dbReference type="OMA" id="FSKWANN"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF1">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="260" mass="29664" checksum="07E429F54C02FE14" modified="2007-05-15" version="1">MDFRDAVLRSNEEAQRNVAPFLRTRALRAVISTFRNDANGDFGKWATNPLVLRMLSEMQTALDEGRASEEEIERFMVNYLSDSKNDGHDAFKKRTTREANLETKDLVGALNEQCELRCKGNAHYERREFAEARECYAQALGIMNLVKGKNPFDADECLKNRAACLRNLGAACMGLKLYGEAIEHLSEYLRASPDDARILCRRGRAFVGRGDFAAAERDFAACLRLDPYDAEPHDELARLRDARRRDRERSRALSRSMFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAU7</accession>
    <name>A4SAU7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sister chromatid cohesion protein DCC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422665.1">
        <property type="nucleotide sequence ID" value="XM_001422628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAU7"/>
    <dbReference type="STRING" id="436017.A4SAU7"/>
    <dbReference type="GeneID" id="5006560"/>
    <dbReference type="Gramene" id="ABP00982">
        <property type="protein sequence ID" value="ABP00982"/>
        <property type="gene ID" value="OSTLU_29384"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29384"/>
    <dbReference type="eggNOG" id="KOG0798">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034504_1_1_1"/>
    <dbReference type="OMA" id="DSESWPF"/>
    <dbReference type="OrthoDB" id="5199543at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034088">
        <property type="term" value="P:maintenance of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395:SF6">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="43434" checksum="BD311F339D305B05" modified="2007-05-15" version="1">MSRRDAVANGAFVAEDGEEFDLVRGADYASERVELLEVDEEILSEILSNDGVIAFKGEPDDVAVVCTRSKTYQVTRVESSNQCLIVGPALGGEEDETEAMEEEEDGPRRATVRAQTSSHLDLTEIAPRLDRLREMMASVAYAGTAEAMDADEGEGEGVGFGFDELNARVQASELEILKCLQEEIVAIEIDGKWRGVDAEYRLHALAMMTASAFGNGWSTSALPTDAVVDAMASDGFAPEMARNTLHAFATKHDVDATWALDEEAVCRALAQRVLRDGAGLKAWRLVEMMDQWREKLSEFNLGHVEAKEEYLSGLALIDRPERAAEAFVRTLIASDLPREPGDRFAALWAVKPRWTLSELDPYLKGQARPGQNIEAQLLKYCRVTQGNPPTYSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBB9</accession>
    <name>A4SBB9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_29554</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422748.1">
        <property type="nucleotide sequence ID" value="XM_001422711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBB9"/>
    <dbReference type="STRING" id="436017.A4SBB9"/>
    <dbReference type="GeneID" id="5006649"/>
    <dbReference type="Gramene" id="ABP01065">
        <property type="protein sequence ID" value="ABP01065"/>
        <property type="gene ID" value="OSTLU_29554"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29554"/>
    <dbReference type="eggNOG" id="KOG2467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022477_0_1_1"/>
    <dbReference type="OMA" id="CQFANVQ"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000050">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF28">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="63"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP01065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="525" mass="57376" checksum="8513F6CE2F23EB75" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBE8</accession>
    <name>A4SBE8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_25890</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422604.1">
        <property type="nucleotide sequence ID" value="XM_001422567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBE8"/>
    <dbReference type="STRING" id="436017.A4SBE8"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="GeneID" id="5006662"/>
    <dbReference type="Gramene" id="ABP00921">
        <property type="protein sequence ID" value="ABP00921"/>
        <property type="gene ID" value="OSTLU_25890"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25890"/>
    <dbReference type="eggNOG" id="ENOG502QR7J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008499_0_0_1"/>
    <dbReference type="OMA" id="MIAVYCT"/>
    <dbReference type="OrthoDB" id="72851at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32044">
        <property type="entry name" value="GLUCOMANNAN 4-BETA-MANNOSYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32044:SF80">
        <property type="entry name" value="XYLOGLUCAN GLYCOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="8">
        <location>
            <begin position="156"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="686"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="762"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="825" mass="89591" checksum="D202BC47437B4748" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBS1</accession>
    <name>A4SBS1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_52141</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422825.1">
        <property type="nucleotide sequence ID" value="XM_001422788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBS1"/>
    <dbReference type="GeneID" id="5006883"/>
    <dbReference type="Gramene" id="ABP01184">
        <property type="protein sequence ID" value="ABP01184"/>
        <property type="gene ID" value="OSTLU_52141"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_52141"/>
    <dbReference type="HOGENOM" id="CLU_011781_2_1_1"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000003">
        <property type="entry name" value="Xaa-pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000007">
        <property type="entry name" value="Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="6">
        <location>
            <begin position="319"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="8">
        <location>
            <begin position="546"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="608" mass="66562" checksum="40BDB5745DA59606" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQF6</accession>
    <name>A4RQF6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_39972</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415726.1">
        <property type="nucleotide sequence ID" value="XM_001415689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQF6"/>
    <dbReference type="STRING" id="436017.A4RQF6"/>
    <dbReference type="GeneID" id="5000023"/>
    <dbReference type="Gramene" id="ABO94018">
        <property type="protein sequence ID" value="ABO94018"/>
        <property type="gene ID" value="OSTLU_39972"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39972"/>
    <dbReference type="eggNOG" id="KOG1590">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099502_5_1_1"/>
    <dbReference type="OMA" id="FLQHFWG"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010119">
        <property type="term" value="P:regulation of stomatal movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="105" mass="11709" checksum="82E3BED8833F5B87" modified="2007-05-15" version="1">MSVRAFINSPTGPRTTHFWGPVANWGFVLAGLADTKKPESMISGPMTGALVVYSGLFMRFAWRVQPRNHILLACHTANANVQAYNFQRWARWNGDAPETTREATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQH3</accession>
    <name>A4RQH3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415388.1">
        <property type="nucleotide sequence ID" value="XM_001415351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQH3"/>
    <dbReference type="STRING" id="436017.A4RQH3"/>
    <dbReference type="GeneID" id="4999895"/>
    <dbReference type="Gramene" id="ABO93680">
        <property type="protein sequence ID" value="ABO93680"/>
        <property type="gene ID" value="OSTLU_13583"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13583"/>
    <dbReference type="eggNOG" id="ENOG502S38U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092939_0_0_1"/>
    <dbReference type="OrthoDB" id="496335at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043186">
        <property type="entry name" value="Str14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44920:SF2">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44920">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 14, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="34"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="22112" checksum="ED9304666B4DE8F7" modified="2007-05-15" version="1">MGSGAREWRRIHAELREKYKMKTVSAKECVQMMARQRAVLLDVRFQPDYEQWSVPGSVSVPYVSGGILAKMRLPGFKKVNANFVEDVERALPDKTTKIILCDIWGGSLETQPPENKSFTDPTKGAGSLPGAFELYQAGYNNLYHLRGGVNQYYEDCEKDKSLPEPDPKTWPGNLEWFGYRQFNGKDRARGQRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQQ5</accession>
    <name>A4RQQ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Calcium-channel protein CCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">OSTLU_13647</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="18">Membrane</location>
            <topology evidence="18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15 18">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415426.1">
        <property type="nucleotide sequence ID" value="XM_001415389.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RQQ5"/>
    <dbReference type="GeneID" id="4999711"/>
    <dbReference type="Gramene" id="ABO93718">
        <property type="protein sequence ID" value="ABO93718"/>
        <property type="gene ID" value="OSTLU_13647"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13647"/>
    <dbReference type="eggNOG" id="KOG2301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000984_0_0_1"/>
    <dbReference type="OMA" id="EGGRKHH"/>
    <dbReference type="OrthoDB" id="496478at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000093">
        <property type="entry name" value="Calcium channel subunit Cch1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031649">
        <property type="entry name" value="GPHH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002077">
        <property type="entry name" value="VDCCAlpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16905">
        <property type="entry name" value="GPHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00167">
        <property type="entry name" value="CACHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 18" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 18" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4 18" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="6 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="9 18" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672812" description="Calcium-channel protein CCH1" evidence="20">
        <location>
            <begin position="20"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
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</entry>
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            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Rouze P."/>
                <person name="Salamov A."/>
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                <person name="Jorgensen R."/>
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                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
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                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
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                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
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</entry>
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    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
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            <end position="348"/>
        </location>
    </feature>
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        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022741"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
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        <source>
            <dbReference type="RuleBase" id="RU000304"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO94145.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="348" mass="38820" checksum="F4402DE506736358" modified="2007-05-15" version="1">MATPATATRARADVDVDDHDARYEPVNDALLGTGSYGYTKLMREKTTGRMYALKYIERGEKITEHVRREITNHRNLSHPNIVKFKEVLVTPTHLAVAMEAIGGGELFGYVQQQGNFTESQARYFFQHLISGVEYLHNMRISHRDLKLENTLVDLTTTPVLKICDFGFSKGGFDSQPKTQIGTPAYISPEVYSGAQPYDGAASDVWACGVLLYVMLVGRYPFSDPQDPNNSHKMMQRVLSAKFDLPQNMTDECKDLLTQIFNVDPKNRITVSGIYHHPWFLHDLSPSVPLGPTQPGPTADDAEGLQCLDAINAIIDVAREPPVKTSSPWGYDEIDGDGIDDGNYLDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRA3</accession>
    <name>A4RRA3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_39889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415863.1">
        <property type="nucleotide sequence ID" value="XM_001415826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRA3"/>
    <dbReference type="STRING" id="436017.A4RRA3"/>
    <dbReference type="GeneID" id="4999765"/>
    <dbReference type="Gramene" id="ABO94155">
        <property type="protein sequence ID" value="ABO94155"/>
        <property type="gene ID" value="OSTLU_39889"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39889"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_4_0_1"/>
    <dbReference type="OMA" id="FAFFGEH"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010043">
        <property type="term" value="P:response to zinc ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051049">
        <property type="entry name" value="Dienelactone_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46623:SF6">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46623">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="26333" checksum="5B7E57649668CC21" modified="2007-05-15" version="1">MSSSFEDVAFGAAGARARVLAAPSSASTRAAVIVLQEWWGVNDVVLAHARRLRDELGVTVLVPDLYRGELGVDVEEAHHLMTNMDWKVATEEIREAAAWLRAERKAERVGVVGFCMGGALTLIAAAKASVDCAVPFYGIPGDDACDVSAIEVPVQGHFGEKDNLVGFSDPGSAKKLRERLRQGEIHFYENVGHAFMNTTPQPYPNFEEREKVQGFPKLDESAVELAWSRVDAFLRKHLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRC8</accession>
    <name>A4RRC8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_19323</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415877.1">
        <property type="nucleotide sequence ID" value="XM_001415840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRC8"/>
    <dbReference type="STRING" id="436017.A4RRC8"/>
    <dbReference type="GeneID" id="4999906"/>
    <dbReference type="Gramene" id="ABO94169">
        <property type="protein sequence ID" value="ABO94169"/>
        <property type="gene ID" value="OSTLU_19323"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19323"/>
    <dbReference type="eggNOG" id="KOG1464">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028981_0_0_1"/>
    <dbReference type="OMA" id="SEENWKD"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000006">
        <property type="entry name" value="COP9 signalosome complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="247"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="442" mass="51282" checksum="9FD7035A9AE6FA51" modified="2007-05-15" version="1">MSDDDDYGFTYSDEDEFNEDEVDIENAYYNAKGSLESGANEAAMKGFEEVIAMEHEKGEWGFKALKQMVKLLYKMNDAGAMLERYKELLTYVNDAVTRNYSEKVLNSILDTIASNEDMGFLQEFYETTLRKLEETKNERLWFKTNLKLCKLVFDAKDFARMQVILKELHKSCQNEDGTVDQRKGTQLLEVYSIEIQMYTAQKNTKKLKDLYEKALEVTSAIPHPRILGIIRECGGKMYMVERDWENAATDFFEAFKSYDEAGSDRRVQCLKYLVLANMLMESEVDPFDAQEVKPFREDKEVTVMRSLVGAYQRNDIAAFEQLLKTHREQVMGDDFIRDYVEDLLKNIRTQVLLRLIEPYTRITIPYISTELNIPEPDVESLMVSLILDRRVDAKIDQRAQVVHIAREDPRAIDAIARARGFANWSERLRDLHLTVASKLARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRN0</accession>
    <name>A4RRN0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415931.1">
        <property type="nucleotide sequence ID" value="XM_001415894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRN0"/>
    <dbReference type="STRING" id="436017.A4RRN0"/>
    <dbReference type="GeneID" id="4999404"/>
    <dbReference type="Gramene" id="ABO94223">
        <property type="protein sequence ID" value="ABO94223"/>
        <property type="gene ID" value="OSTLU_13896"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13896"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029231_2_0_1"/>
    <dbReference type="OMA" id="REEWMTH"/>
    <dbReference type="OrthoDB" id="342454at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022226">
        <property type="entry name" value="DUF3752"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47422">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47422:SF1">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12572">
        <property type="entry name" value="DUF3752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="247"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="528"/>
        </location>
    </feature>
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        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="528" mass="58653" checksum="FB3819C557410AC9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRR1</accession>
    <name>A4RRR1_OSTLU</name>
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        <recommendedName>
            <fullName evidence="4">DUF4079 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_13920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415614.1">
        <property type="nucleotide sequence ID" value="XM_001415577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRR1"/>
    <dbReference type="STRING" id="436017.A4RRR1"/>
    <dbReference type="GeneID" id="4999879"/>
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        <property type="protein sequence ID" value="ABO93906"/>
        <property type="gene ID" value="OSTLU_13920"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13920"/>
    <dbReference type="eggNOG" id="ENOG502QT15">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OMA" id="HAIITCS"/>
    <dbReference type="OrthoDB" id="4914at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025067">
        <property type="entry name" value="DUF4079"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34679">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34679:SF2">
        <property type="entry name" value="OS02G0122500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13301">
        <property type="entry name" value="DUF4079"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="22657" checksum="AC3DDC879BFA7B75" modified="2007-05-15" version="1">MENAKAAVSALAIATCVTAMPEMAHASGGEFGILEGRSAALLHPIGLGSLYAVTLYAGWLGLQWRRVRTVGDEIAGLKKTLPEDAAAAAGSAVAKQIDELTSTRKELVAGKFKDKHANMGYLLLALGVTLAVEGGMNTYLRVGKLFPGPHLYAGASIVVLWAMAAGLVPQMEKGNQKARDLHIALNCVNLALFTWQIPTGLEIVGKVFQFTSWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRV1</accession>
    <name>A4RRV1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_39880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRV1"/>
    <dbReference type="GeneID" id="4999961"/>
    <dbReference type="Gramene" id="ABO94259">
        <property type="protein sequence ID" value="ABO94259"/>
        <property type="gene ID" value="OSTLU_39880"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39880"/>
    <dbReference type="eggNOG" id="KOG4151">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2942533at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="105" mass="11812" checksum="9ACD47C1C5510D34" modified="2007-05-15" version="1" fragment="single">MKSAHRGGEDPDDEVFTQRAVELKDEANALYGAGSIKRALEVYEQALNLLPERDQTRAMIHSNRAACFSKMQCYADVVAEASRALALDGKSYKAYWHRAQAYMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS34</accession>
    <name>A4RS34_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415672.1">
        <property type="nucleotide sequence ID" value="XM_001415635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS34"/>
    <dbReference type="GeneID" id="4999851"/>
    <dbReference type="Gramene" id="ABO93964">
        <property type="protein sequence ID" value="ABO93964"/>
        <property type="gene ID" value="OSTLU_29229"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29229"/>
    <dbReference type="HOGENOM" id="CLU_722393_0_0_1"/>
    <dbReference type="OrthoDB" id="10361367at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="383" mass="42592" checksum="4FF748CFB81BE7EE" modified="2007-05-15" version="1">METFTQGARKARATDALMRDENEVAQRIRKDRFKTVVVLLTLGVFAAAFLMLSTTNVVASLGVRGGAVNALGRTLRTGRQGGRARSGVLAGLGSSLERGRSVMARFGAPELNTPIFFVSVGTTDDETQMKDSLERMRVRSGLEPETLKRLVTVSKGVDATAWPDNTHLVEYAVKDIRTLAAQHGNVLAELPWVQIIELSKQTQDGRLPVEWRRLAHHVGCMYAHLFQWQLVKEQKLKKALIFESDGVQQTDLPFAEAQKAIDRLPEDADLLLFSFGNTPGGDLVDQWKGHGDDGTPVDVHLYKWNKWNAVAGLQSYVITDNFVRKVQEYISHKGADMIDAWLLGKMCVVGKDKDWNMRGLGETQFMPPGSKPILNCYHATTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS78</accession>
    <name>A4RS78_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415695.1">
        <property type="nucleotide sequence ID" value="XM_001415658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS78"/>
    <dbReference type="GeneID" id="4999982"/>
    <dbReference type="Gramene" id="ABO93987">
        <property type="protein sequence ID" value="ABO93987"/>
        <property type="gene ID" value="OSTLU_29274"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29274"/>
    <dbReference type="HOGENOM" id="CLU_1470521_0_0_1"/>
    <dbReference type="OrthoDB" id="5627at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="20537" checksum="82846264B6FFFD58" modified="2007-05-15" version="1">MLGTNSAFASAGVVLAGRELVRDGDDGDRGYGLRTAEEARARAYVEEELKRRRGEVVEDDAEASGAAAAGGDDNRGAESWLTAIEEVDVSVERRMQNIEETERAKRAMLDGARPGELGAFDALKPSHMELKEAKKRPPPSETALARRQFVTGFGAKRERQEASEESRREKERRKNFFKKKRNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSG6</accession>
    <name>A4RSG6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416252.1">
        <property type="nucleotide sequence ID" value="XM_001416215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSG6"/>
    <dbReference type="GeneID" id="5000479"/>
    <dbReference type="Gramene" id="ABO94545">
        <property type="protein sequence ID" value="ABO94545"/>
        <property type="gene ID" value="OSTLU_30260"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30260"/>
    <dbReference type="HOGENOM" id="CLU_051989_4_0_1"/>
    <dbReference type="OMA" id="FREWREM"/>
    <dbReference type="OrthoDB" id="498000at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="26357" checksum="325FA34210E5A4C3" modified="2007-05-15" version="1">MRDSATSTRAHWASPEIRRFRRLDAETRASEASEPAVVFVGSSIFREWREVRDFEEDWRGRMGDARRAVNRAFGGAETTDLLTFFDDVLPRGRADVRAIVYYCGSNDVSVGRSAREVFENFKRFAESARRERSARLGVVFVGMIDSPQKRAFALSHVVRETNALCEAWCAKTPGAVYADVTETFADASSFREDGTHLRPEAYDGFRDAIARAVVEAVAHASPPPDDAFLPPAMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSV5</accession>
    <name>A4RSV5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DDE Tnp4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Cup67</name>
        <name evidence="5" type="ORF">OSTLU_119558</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416176.1">
        <property type="nucleotide sequence ID" value="XM_001416139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSV5"/>
    <dbReference type="GeneID" id="5000285"/>
    <dbReference type="Gramene" id="ABO94469">
        <property type="protein sequence ID" value="ABO94469"/>
        <property type="gene ID" value="OSTLU_119558"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119558"/>
    <dbReference type="HOGENOM" id="CLU_457417_0_0_1"/>
    <dbReference type="OrthoDB" id="2668416at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23080">
        <property type="entry name" value="THAP DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="4">
        <location>
            <begin position="405"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="213"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="597" mass="68730" checksum="2DEE940B5E4DB9AB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT35</accession>
    <name>A4RT35_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Homogentisate phytylprenyltransferase/homogentisic acid geranylgeranyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Hpt1</name>
        <name evidence="8" type="ORF">OSTLU_119481</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416140.1">
        <property type="nucleotide sequence ID" value="XM_001416103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT35"/>
    <dbReference type="STRING" id="436017.A4RT35"/>
    <dbReference type="GeneID" id="5000383"/>
    <dbReference type="Gramene" id="ABO94433">
        <property type="protein sequence ID" value="ABO94433"/>
        <property type="gene ID" value="OSTLU_119481"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119481"/>
    <dbReference type="eggNOG" id="ENOG502R0I3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048963_0_1_1"/>
    <dbReference type="OMA" id="LAWINCC"/>
    <dbReference type="OrthoDB" id="1502398at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13960">
        <property type="entry name" value="PT_UbiA_HPT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044502">
        <property type="entry name" value="AtHST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43009:SF7">
        <property type="entry name" value="HOMOGENTISATE GERANYLGERANYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43009">
        <property type="entry name" value="HOMOGENTISATE SOLANESYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="387" mass="43286" checksum="F52A3925165F78D1" modified="2007-05-15" version="1">MTPTFASLALRGCFLWAKMQVNDRVTYSRQCSTVLCTNRKAQRTNVLPGGSGRLSQVLRASRFVESTAAHRNSGFSQHSGFIDDFRKIPNLSRSLFGFMRPHTIYGTLISIVSISLMAASVDSSPYNTLLWKLWQVIFCALAMNVTIVGLNQIYDKKMDKINKPYLPLVSGGFTTDTALTTIAVCCSSSVICGTLTQSFHLLTTLVLSLLLGVIYSTDFKLLRWKRIPALAIVCILSVRAILVQWGFFGHFMSSYIPYWAMPENLAFSILFMSVYSVVIALLKDTPDLVGDSQSGMRTLAVRLGVKPVLRLCCLLLFLAYSSGILVGLSRSDSCIQMIVLTLGHSLSLILIFIKYSKTEHASSSSLYSFYMFIWKMFYCEYFMLPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT51</accession>
    <name>A4RT51_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_24052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416375.1">
        <property type="nucleotide sequence ID" value="XM_001416338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT51"/>
    <dbReference type="GeneID" id="5000276"/>
    <dbReference type="Gramene" id="ABO94668">
        <property type="protein sequence ID" value="ABO94668"/>
        <property type="gene ID" value="OSTLU_24052"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24052"/>
    <dbReference type="eggNOG" id="ENOG502S2PZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_667909_0_0_1"/>
    <dbReference type="OMA" id="CIRGAHM"/>
    <dbReference type="OrthoDB" id="10267325at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="359" mass="39011" checksum="A38E0BF78DA2CC27" modified="2007-05-15" version="1">MSVFSRKLKSNKATKSPPSAPPVKHVVAQSAPSPSVVTAGLTTLPTVLDKAGPALVAASRLAAQSEPYAVATFEFCRKTWLALQPYHPQEFGPAIVGFILCFFGGYFATITAAVEAYRITGYANTRDALVIIWRNIEAAQRASLKDDELDEDHNGIPDTQEITKKALVVRKIGVVAKSMDPEQVGDALGAIYMGFVAVVATLRVHFAACVSLGVAVGDIVHNIVDENLTPVLMMSTPKEYQKWVGPGVRYACKVIGVIAAWLVQQAITAYHSATRGAQLFARGLLTYLVRHKYLGPNVIDEKGTVFNFAIFVLAMTGFWSQIMYGFKLPFPISVFLIPIRMLEFALRVCVGTMRDGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTE4</accession>
    <name>A4RTE4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Possible high light inducible protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HLIP</name>
        <name evidence="2" type="ORF">OSTLU_14124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416326.1">
        <property type="nucleotide sequence ID" value="XM_001416289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTE4"/>
    <dbReference type="STRING" id="436017.A4RTE4"/>
    <dbReference type="GeneID" id="5000438"/>
    <dbReference type="Gramene" id="ABO94619">
        <property type="protein sequence ID" value="ABO94619"/>
        <property type="gene ID" value="OSTLU_14124"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14124"/>
    <dbReference type="eggNOG" id="ENOG502RXUG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1963285_0_0_1"/>
    <dbReference type="OMA" id="FTPSNEI"/>
    <dbReference type="OrthoDB" id="2019915at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009642">
        <property type="term" value="P:response to light intensity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="128" mass="13963" checksum="FAFDFC515955C097" modified="2007-05-15" version="1">MMLALSTRAPAGGAAISSARGGKRSTRGARRCAANAVAASAETKKPTTVEYQRERAKMMVRYFKEKQYDQAVEDAQVFGFTPSNEINNGRWTMFGLLVGMLTEFATGVDFIDQIKLTVSVLGIADIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTK2</accession>
    <name>A4RTK2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29854</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416303.1">
        <property type="nucleotide sequence ID" value="XM_001416266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTK2"/>
    <dbReference type="GeneID" id="5000497"/>
    <dbReference type="Gramene" id="ABO94596">
        <property type="protein sequence ID" value="ABO94596"/>
        <property type="gene ID" value="OSTLU_29854"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29854"/>
    <dbReference type="HOGENOM" id="CLU_1963284_0_0_1"/>
    <dbReference type="OrthoDB" id="10623427at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="128" mass="14698" checksum="954124E7CF0DBF0A" modified="2007-05-15" version="1">MGSPWSFGVYKSSKFLRSSTTFAWQKLPLRVVNARGLIRLRPHVLLSRRSKVQPTALTWVSRWLLSTVACSIVSATSLDDCLRFLARDERFAVIPKTDADFTVRLNQPLRSNELWFVARFSSCGRMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTQ5</accession>
    <name>A4RTQ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
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        <property type="protein sequence ID" value="ABO95122"/>
        <property type="gene ID" value="OSTLU_33850"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="10257948at2759"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="88"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="27719" checksum="3C0E5EDDDF8F8E7C" modified="2007-05-15" version="1">MDGGKFRDTMHSLNYGTVMEAAARNYMEEKTREDAHAKARARARVLDAKELCEDPDLEDIHRERVQAMKEAQERRMTMERTGHGTLTEVDEKEFLPEVTTTHRVVAHFYHQEFERCRIMDKHLSALAKKFFDTKFIKISAPDAPFFVTKLQVKVLPCLIFFKDGVAFDRLVGFEELGGKDDYPTAKLERILLKADAVVQPEKNESDSEDEVEEIRREAMSRMMRTGGFKANSDDEDSDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTW5</accession>
    <name>A4RTW5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_45141</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FGGY kinase family.</text>
    </comment>
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    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416856.1">
        <property type="nucleotide sequence ID" value="XM_001416819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTW5"/>
    <dbReference type="STRING" id="436017.A4RTW5"/>
    <dbReference type="GeneID" id="5001092"/>
    <dbReference type="Gramene" id="ABO95149">
        <property type="protein sequence ID" value="ABO95149"/>
        <property type="gene ID" value="OSTLU_45141"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45141"/>
    <dbReference type="eggNOG" id="KOG2517">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_2_3_1"/>
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    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
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        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
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    </dbReference>
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        <property type="term" value="P:response to microbial phytotoxin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:response to molecule of bacterial origin"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ASKHA_NBD_FGGY_GK1-3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000108">
        <property type="entry name" value="Glycerol kinase, glycosomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
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        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042018">
        <property type="entry name" value="GK1-3_metazoan-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000756">
        <property type="entry name" value="PRK00047.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF69">
        <property type="entry name" value="GLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="12">
        <location>
            <begin position="274"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="522" mass="56223" checksum="F061B433A311DA6A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU50</accession>
    <name>A4RU50_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416895.1">
        <property type="nucleotide sequence ID" value="XM_001416858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU50"/>
    <dbReference type="GeneID" id="5001037"/>
    <dbReference type="Gramene" id="ABO95188">
        <property type="protein sequence ID" value="ABO95188"/>
        <property type="gene ID" value="OSTLU_30496"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30496"/>
    <dbReference type="HOGENOM" id="CLU_2744569_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="71" mass="7948" checksum="AEFD031BE79F1D04" modified="2007-05-15" version="1">MAPQSEAAKRFMRSYDKFTILLCTSAAVAYGAARYYDLEPAPDDFDLKKWFMGGYDVPKVDEAANSAQKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUD0</accession>
    <name>A4RUD0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MC family transporter: carnitine/acylcarnitine</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_30578</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416649.1">
        <property type="nucleotide sequence ID" value="XM_001416612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUD0"/>
    <dbReference type="GeneID" id="5000867"/>
    <dbReference type="Gramene" id="ABO94942">
        <property type="protein sequence ID" value="ABO94942"/>
        <property type="gene ID" value="OSTLU_30578"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30578"/>
    <dbReference type="eggNOG" id="KOG0758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_16_3_1"/>
    <dbReference type="OMA" id="CLMRSIP"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF24">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="94"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="198"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="289" mass="31282" checksum="5D71CB9C5078BF3E" modified="2007-05-15" version="1">MKFAKDVFAGTCGGVTVTLLGHPFDTVKVLLQTQSSKNPVYSGAVDAASKVIKAEGVGGLYRGVTSPLAGQMFFRATLFFAYARAKEFVGVSPEDPLSYAKAGAMAWLAGTFFESPIDLYKSQWQCQLVKAKADPTYKSPYGSVVDVVKESWKYNGVRGPYQAFHATMARNLPAGAVYFGVFENVKNSFAKTNEDGKATNAQIILSGGIGGFFYWSLFYPIDVIKSALMTDAVNPAKRKFTGFFDAAGKLYASGGVKAFYRGLVPCLLRASPANAGMLFTVDYIRRIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUH3</accession>
    <name>A4RUH3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_6426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416959.1">
        <property type="nucleotide sequence ID" value="XM_001416922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUH3"/>
    <dbReference type="STRING" id="436017.A4RUH3"/>
    <dbReference type="GeneID" id="5001115"/>
    <dbReference type="Gramene" id="ABO95252">
        <property type="protein sequence ID" value="ABO95252"/>
        <property type="gene ID" value="OSTLU_6426"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6426"/>
    <dbReference type="eggNOG" id="ENOG502QUQV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079763_0_0_1"/>
    <dbReference type="OMA" id="MVEMHLL"/>
    <dbReference type="OrthoDB" id="4812at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009534">
        <property type="term" value="C:chloroplast thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009528">
        <property type="term" value="C:plastid inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009527">
        <property type="term" value="C:plastid outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009532">
        <property type="term" value="C:plastid stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010319">
        <property type="term" value="C:stromule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050829">
        <property type="term" value="P:defense response to Gram-negative bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072597">
        <property type="term" value="P:maintenance of protein location in chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902458">
        <property type="term" value="P:positive regulation of stomatal opening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045038">
        <property type="term" value="P:protein import into chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903426">
        <property type="term" value="P:regulation of reactive oxygen species biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000070">
        <property type="term" value="P:regulation of response to water deprivation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010182">
        <property type="term" value="P:sugar mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017499">
        <property type="entry name" value="Thf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34793">
        <property type="entry name" value="PROTEIN THYLAKOID FORMATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34793:SF1">
        <property type="entry name" value="PROTEIN THYLAKOID FORMATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11264">
        <property type="entry name" value="ThylakoidFormat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="203" mass="21970" checksum="6B67656F347F2CA7" modified="2007-05-15" version="1" fragment="single">TVSDTKAKFLQAYPYPIPSVWSTVTQELLVQGHFAKYNAKSEYSELASLGFVSVFDQLYEGFPSETEKVKIFNAFLGALGEDAAKTRADAEALGAFAASAGGVDGLSANPIFATMAAKSAENKLMYTKYIAIGIFRMLELAKATDPKALEALAQAGGLSFKKVNGDLAMYKGLLSKLASAKELQEEFLEREKRKTAERMAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUZ6</accession>
    <name>A4RUZ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_8067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417049.1">
        <property type="nucleotide sequence ID" value="XM_001417012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUZ6"/>
    <dbReference type="STRING" id="436017.A4RUZ6"/>
    <dbReference type="GeneID" id="5000827"/>
    <dbReference type="Gramene" id="ABO95342">
        <property type="protein sequence ID" value="ABO95342"/>
        <property type="gene ID" value="OSTLU_8067"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8067"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1860439_0_0_1"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="138" mass="14725" checksum="8D32FAE5699D0104" modified="2007-05-15" version="1" fragment="single">KLDEFWARSSSSGGATVVLAASGEDGFAVAHAGDSAAYACFADSSGRAKARRLTQDHGLDNENERKRLDALGVKIVRARGKLRVGGELLVTRALGGARHKAFGVVATPEIMRRRWKRDEMGLILTSDGTTDALRADDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV27</accession>
    <name>A4RV27_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CobW/HypB/UreG nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417065.1">
        <property type="nucleotide sequence ID" value="XM_001417028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV27"/>
    <dbReference type="STRING" id="436017.A4RV27"/>
    <dbReference type="GeneID" id="5000631"/>
    <dbReference type="Gramene" id="ABO95358">
        <property type="protein sequence ID" value="ABO95358"/>
        <property type="gene ID" value="OSTLU_14784"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14784"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_1_2_1"/>
    <dbReference type="OMA" id="ECADAMC"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF46">
        <property type="entry name" value="ZINC CHAPERONE YEIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="1">
        <location>
            <begin position="5"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="378" mass="41325" checksum="EA3123740D6E493F" modified="2007-05-15" version="1">MARTPVNVITGALGAGKTTHVLRALASAKPANETWAVVVNDFGALGIDGALLDDAVGTRERDADASGRTIVREVSGGCACCATAAPFVVAVTQVLRRYRPARVLVEPSGMGDAGRVIDALRSEHLEASVDVRATICVVDVRVFGEDEGKAAVLRSELFKAQTECADAMCGSFADAASEAEVEAFLAFGRGFWPKKSAVFLARDRANGMDLALLDGRCGWEPSELPTEATTTTTTTTSSRPFTLEPRLTANAPPWMVKQESDRYASCGYAFHVDDVFVRPKLKAFFEEFVLRRVDVARFKGVLRLGADWVRPDIVESIHRSEGTKVRTRTITFASVAYRRDSRFELIRERGVDADADAEEAAFWDDIRDRLVECRKIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV67</accession>
    <name>A4RV67_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_2726</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417086.1">
        <property type="nucleotide sequence ID" value="XM_001417049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV67"/>
    <dbReference type="STRING" id="436017.A4RV67"/>
    <dbReference type="GeneID" id="5000897"/>
    <dbReference type="Gramene" id="ABO95379">
        <property type="protein sequence ID" value="ABO95379"/>
        <property type="gene ID" value="OSTLU_2726"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2726"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029162_1_0_1"/>
    <dbReference type="OMA" id="FTKGEKW"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699:SF5">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46699">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE STN8, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="363" mass="40574" checksum="3DBFB2B139876A8A" modified="2007-05-15" version="1" fragment="single">GLVVVNGSKYKKSDFEMERQIGEGSFGVVYEGRVAVNDARGLRKGDAVVLKRPKLTVEGAAELQEIESWMNDRVSRDAKGACAEFVGSFRVTRDDWLASGTNDALSKEGLWLVWRYQGDRTLAQYLAQPDYPTGLAKALLDRDDVYRGDAAVELEITQRAISQLLSSLMAMHRAGLVHRDVKPHNLVLAREPTPEFKVIDLGACACFRSGMNFTPDETIMDPKYAPPEEFLIPTDDAPDLRKMFAPVALAAGTTAWLSHRPDRFDMYSTGIVLMQLAMPSLRTNSGLQSFNRGLKKFKYDLQKWREANKGQLSRSKTAVLDAGDGAGWELAADLLRPRPYEAEDDQEARERPSAEQALKHRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVB1</accession>
    <name>A4RVB1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416810.1">
        <property type="nucleotide sequence ID" value="XM_001416773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVB1"/>
    <dbReference type="GeneID" id="5000977"/>
    <dbReference type="Gramene" id="ABO95103">
        <property type="protein sequence ID" value="ABO95103"/>
        <property type="gene ID" value="OSTLU_30911"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30911"/>
    <dbReference type="HOGENOM" id="CLU_566661_0_0_1"/>
    <dbReference type="OMA" id="REDFATS"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
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        <location>
            <begin position="426"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
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            <begin position="202"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
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        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="509" mass="56157" checksum="CC388956FAB777C7" modified="2007-05-15" version="1">MTSPPRSVSQALLSPVRHVLASLRTNSFEGERFVGDEGGEDKREEIFARLEAHVENGLKKNTLSDGDIFELIRLTTAFGLEEVGTSNAGAALEAARYVLTGSSATATTGDSEVFHASTPMSANGTLTAQPLSPPPTATTLLARTASGGAQTAPNTPQPDDGGRMESATTATSTMRDAARATKSSSLRSKSKSALSSIAGATDESKKPKPRRRTDGETVEDRLLREWILRQARESARMEEIRQAELAATRKANLTGRQIMESVESLRARGEASRKQQEEARKAAEASARRLAMRSVSAHIGKKTRELTAKMPDFSSRQQRFASKAAERAEQRRREAEEEKRAKEMVDVSGERVPMTNRAAQTHRTLEDLQAWNDRREEKIRSAKAKKEQEELHGATFAPVLDQRSLRMALKKRMALKKSREDFATSINHERDADDARHPFTPRLVSRQRETPRDVVLERLYSASKSTQKKSATPDRTPREHWGGYGVDDDHPDADAGASGFISLAELDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVD8</accession>
    <name>A4RVD8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_92541</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001417367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVD8"/>
    <dbReference type="STRING" id="436017.A4RVD8"/>
    <dbReference type="GeneID" id="5001230"/>
    <dbReference type="Gramene" id="ABO95697">
        <property type="protein sequence ID" value="ABO95697"/>
        <property type="gene ID" value="OSTLU_92541"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92541"/>
    <dbReference type="eggNOG" id="KOG0825">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_343760_0_0_1"/>
    <dbReference type="OMA" id="IKWIAPH"/>
    <dbReference type="OrthoDB" id="498914at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
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        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="61"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="744"/>
            <end position="793"/>
        </location>
    </feature>
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        <location>
            <begin position="148"/>
            <end position="252"/>
        </location>
    </feature>
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        <location>
            <begin position="331"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="788"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="793"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="824" mass="89591" checksum="8F86F9B8B8683E02" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVU4</accession>
    <name>A4RVU4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TRAF-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_31099</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417470.1">
        <property type="nucleotide sequence ID" value="XM_001417433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVU4"/>
    <dbReference type="STRING" id="436017.A4RVU4"/>
    <dbReference type="GeneID" id="5001408"/>
    <dbReference type="Gramene" id="ABO95763">
        <property type="protein sequence ID" value="ABO95763"/>
        <property type="gene ID" value="OSTLU_31099"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31099"/>
    <dbReference type="eggNOG" id="ENOG502QSC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025538_0_0_1"/>
    <dbReference type="OMA" id="KSIDMKC"/>
    <dbReference type="OrthoDB" id="1737200at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF94">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02176">
        <property type="entry name" value="zf-TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TRAF-type" evidence="6">
        <location>
            <begin position="197"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="197"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="368" mass="40632" checksum="03ACB5230F050F9D" modified="2007-05-15" version="1">MSDDTSESELPSRALESTAPESRLTCDHVCCSTSNNVASALFNAVVRAVVFQSSVLSSTSSKLKSATECAKELEEALVRGAKGSNRTLVDLSNAINAWTAGKKGLMSGVFSSTEDGVAATTTLLLDNDDAWPEAERHKLAIRLVRDYYDTDFQAHCRKSCVDEDALFEHKISCKFLPVSCSNEGCPASFSKHSQEKHDNRCSYKLIDCRLECGRQIARGEMEAHAAGDCAMREVECPYAELGCQHPVRLGKMSEHLFENAENHLRMLYTAETKVSTRVSALERWAQAVVDDDEHRREGLRAIDTALLTLETKHAELDKSHVGSKSHITKLESRVKDLEATVKKQSAELASFRKTVDGLRQSFAQIAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVZ8</accession>
    <name>A4RVZ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Diacylglycerol kinase</fullName>
            <shortName evidence="9">DAG kinase</shortName>
            <ecNumber evidence="9">2.7.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_31162</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eukaryotic diacylglycerol kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.107" evidence="9"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417237.1">
        <property type="nucleotide sequence ID" value="XM_001417200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVZ8"/>
    <dbReference type="STRING" id="436017.A4RVZ8"/>
    <dbReference type="GeneID" id="5001327"/>
    <dbReference type="Gramene" id="ABO95530">
        <property type="protein sequence ID" value="ABO95530"/>
        <property type="gene ID" value="OSTLU_31162"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31162"/>
    <dbReference type="eggNOG" id="KOG1169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003770_3_0_1"/>
    <dbReference type="OMA" id="YAIMELP"/>
    <dbReference type="OrthoDB" id="242257at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000756">
        <property type="entry name" value="Diacylglycerol_kin_accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF54">
        <property type="entry name" value="DIACYLGLYCEROL KINASE THETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00609">
        <property type="entry name" value="DAGK_acc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00045">
        <property type="entry name" value="DAGKa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="DAGKc" evidence="11">
        <location>
            <begin position="34"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO95530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="434" mass="48924" checksum="24D7C86ECD720F13" modified="2007-05-15" version="1">MGKPWLEGFKFATYLAVPIALTVTFAFNPDNLNGIIRNVFVFVNKKSGGRRGREVLRRLRETLKPPHVVLDATKVRGAIDRGEVDWDAETRVLVAGGDGTVGMVVDALRRRRREPPPIAIAPLGTGNDLARVLGWSGDVWDDSRLFSERRVVSTLRRARLQRVDRWSLEITRPRRRSTTKKLFSNYMGIGVDARAALAFDSARKDRRWTWLFVHALTNKLLYAVFGARDFIEHSFAGLKRDVEVTVDGKVIDFPEDTEGIILLNINSFSGGVRMWATSDEFTKSLKDDGVLEIVAVSGALHLGQLNARLAKPVQVAQGCDVRIELKRDLPVQIDGEPWLQRGAATLRVSLNDSFTMLRRPRQDRINDLLARWSRSNGFASEDDDATSASSDERRARRRRAFAFAFAFALCLALAAFVFPWRHRLARLFALRLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW02</accession>
    <name>A4RW02_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31166</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417240.1">
        <property type="nucleotide sequence ID" value="XM_001417203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW02"/>
    <dbReference type="STRING" id="436017.A4RW02"/>
    <dbReference type="GeneID" id="5001328"/>
    <dbReference type="Gramene" id="ABO95533">
        <property type="protein sequence ID" value="ABO95533"/>
        <property type="gene ID" value="OSTLU_31166"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31166"/>
    <dbReference type="eggNOG" id="KOG2186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1345171_0_0_1"/>
    <dbReference type="OMA" id="QQHTSCV"/>
    <dbReference type="OrthoDB" id="21474at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.490:FF:000001">
        <property type="entry name" value="cell growth-regulating nucleolar protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039999">
        <property type="entry name" value="LYAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014898">
        <property type="entry name" value="Znf_C2H2_LYAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13100:SF10">
        <property type="entry name" value="CELL GROWTH-REGULATING NUCLEOLAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13100">
        <property type="entry name" value="CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08790">
        <property type="entry name" value="zf-LYAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51804">
        <property type="entry name" value="ZF_C2HC_LYAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="113"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="204" mass="22319" checksum="6247E4D9A6A5D69C" modified="2007-05-15" version="1">MPWFVCESCGDTLKKPKIKAHFNRCAAEAFSCIDCSATFDRRSVQNHVACVTEHEKYALGATKGAAGHERARAVAAEGTERRGGDGGETFGEEFLSTRPPWRCSCCGVSCTSEETLSGHASGKKHKSKARSARARAAGETPGNAETAEAVEAKAKDERVEKKVKKEKKEKKEKKEKKEKKEKKGKKSSEKDSSDDGPKRKKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWD3</accession>
    <name>A4RWD3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GPI transamidase subunit PIG-U</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31299</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417560.1">
        <property type="nucleotide sequence ID" value="XM_001417523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWD3"/>
    <dbReference type="STRING" id="436017.A4RWD3"/>
    <dbReference type="GeneID" id="5001615"/>
    <dbReference type="Gramene" id="ABO95853">
        <property type="protein sequence ID" value="ABO95853"/>
        <property type="gene ID" value="OSTLU_31299"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31299"/>
    <dbReference type="eggNOG" id="KOG2552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1654649_0_0_1"/>
    <dbReference type="OrthoDB" id="498246at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009600">
        <property type="entry name" value="PIG-U"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06728">
        <property type="entry name" value="PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="20162" checksum="6C6BCE8D6AAAD175" modified="2007-05-15" version="1">MGDDFPKWWRAAVTFAVMSEDQTPNLGLHWYLFTTMFDQFRLFYVVALNAIPLALSAPLTLGFADDPLVAMTLCLIAISTCAPYPTANDFVTYVSLLSVVAMDDRGNPLVYVKYGAVIAGGFLYVALLSPLTWYMWIHTRVANANFYYAITLVYACTQTLLSTQVARSVARFRRAGKKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWL2</accession>
    <name>A4RWL2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_37097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417351.1">
        <property type="nucleotide sequence ID" value="XM_001417314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWL2"/>
    <dbReference type="STRING" id="436017.A4RWL2"/>
    <dbReference type="GeneID" id="5001570"/>
    <dbReference type="Gramene" id="ABO95644">
        <property type="protein sequence ID" value="ABO95644"/>
        <property type="gene ID" value="OSTLU_37097"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37097"/>
    <dbReference type="eggNOG" id="KOG3115">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050910_1_3_1"/>
    <dbReference type="OMA" id="DPWFKRR"/>
    <dbReference type="OrthoDB" id="47276at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF21">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="26832" checksum="8F907CCB5CC8DBA3" modified="2007-05-15" version="1">MTEASAFADLNLQEASKKVRGVRVRQHVNPLTKRFQTQAPAPAWREVYRDAGKPLTIDVGCAGGRFDLLYAKRNPDKNVLGLDIREPLVERGLSWGEASGVVDNVHFATCNATVSIGEWIKSYHETSGATVDLVTILHPDPHFKTKHKKRRIVQATMVRQLAREMRPGARVYLQSDVEELTEDMREKFERFSDGCFDLDHEFENPIGIPSEREVQTLGEGLPVYRVMLRRTEKACAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWS0</accession>
    <name>A4RWS0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_87139</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417626.1">
        <property type="nucleotide sequence ID" value="XM_001417589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWS0"/>
    <dbReference type="STRING" id="436017.A4RWS0"/>
    <dbReference type="GeneID" id="5001645"/>
    <dbReference type="Gramene" id="ABO95919">
        <property type="protein sequence ID" value="ABO95919"/>
        <property type="gene ID" value="OSTLU_87139"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87139"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="CAFADRQ"/>
    <dbReference type="OrthoDB" id="496782at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="156"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="335" mass="37046" checksum="5CEAC1DB9E75C340" modified="2007-05-15" version="1">MMRSTRAAANELARGTTVGKNARYEVTKLINRGGTALVYEGVDRETGEKVALKCLDVGDGARVKVPLAAVKREIKYATKLMASTSRVVRLMNVVNDGEDLLVLVFELARGVDVLDFINARGGRLDEVTARRLFSQLVEAIRMIHDHGLCHRDVKPENAIVCEPHGDLKLIDFGLAKGLDSVATRAVGTPDYMAPEMLDKHDGDGNVRRTKYDAKACDVWSCGVFCYIMLTGTYPFQNPDRPNSVKLTLENIVKGNIAPMSRSISNEVKDLILRMLHPDPKKRITLREVSRHPWVLAGSPARGTGAVSRRLSLVELGRRARAMLTGQRRKSEDTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX17</accession>
    <name>A4RX17_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_10510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417675.1">
        <property type="nucleotide sequence ID" value="XM_001417638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX17"/>
    <dbReference type="STRING" id="436017.A4RX17"/>
    <dbReference type="GeneID" id="5001676"/>
    <dbReference type="Gramene" id="ABO95968">
        <property type="protein sequence ID" value="ABO95968"/>
        <property type="gene ID" value="OSTLU_10510"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10510"/>
    <dbReference type="eggNOG" id="KOG1040">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024513_2_2_1"/>
    <dbReference type="OMA" id="KSWDCPW"/>
    <dbReference type="OrthoDB" id="306690at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000017">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor 30 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="82" mass="9887" checksum="2F1E49384AAF4424" modified="2007-05-15" version="1" fragment="single">RKNYRQTVCRHWLRNLCMKGNACGFLHQFDKSRMPTCRFFAKYGECKEPDCPYKHSLEDMKDCNMYKLGFCIHGSLCRFRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX33</accession>
    <name>A4RX33_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_24508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417925.1">
        <property type="nucleotide sequence ID" value="XM_001417888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX33"/>
    <dbReference type="GeneID" id="5001686"/>
    <dbReference type="Gramene" id="ABO96218">
        <property type="protein sequence ID" value="ABO96218"/>
        <property type="gene ID" value="OSTLU_24508"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24508"/>
    <dbReference type="HOGENOM" id="CLU_426645_0_0_1"/>
    <dbReference type="OrthoDB" id="543760at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="770" mass="85999" checksum="7AF301D292FE61CD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX47</accession>
    <name>A4RX47_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31566</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="9"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417695.1">
        <property type="nucleotide sequence ID" value="XM_001417658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX47"/>
    <dbReference type="STRING" id="436017.A4RX47"/>
    <dbReference type="GeneID" id="5002043"/>
    <dbReference type="Gramene" id="ABO95988">
        <property type="protein sequence ID" value="ABO95988"/>
        <property type="gene ID" value="OSTLU_31566"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31566"/>
    <dbReference type="eggNOG" id="KOG3115">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050910_3_1_1"/>
    <dbReference type="OMA" id="LPNYFAK"/>
    <dbReference type="OrthoDB" id="47276at2759"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03055">
        <property type="entry name" value="tRNA_methyltr_TrmB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025763">
        <property type="entry name" value="Trm8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00091">
        <property type="entry name" value="tRNA (guanosine(46)-N7)-methyltransferase TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF16">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="118"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="151"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="249"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="275" mass="31107" checksum="E94A4E45806E7614" modified="2007-05-15" version="1">MATPASTVAGTRVVKIGDASLEVPSFVSASNVGTSAPRKKHFRQRAHCNPLNDGYYYAPVGPWEIDWREHYEEFFAKRDGDGDAGSLKIRFADVGCGFGGMLVRLAEVFPEKLMLGMEIRDKVSEYVRERCAALRKDHPGKYWNISCVRANAMKNLPQYFEKGQLEKLFFLFPDPHFKAANHRRRIVTTTLLAEYAYVLAEGGILYTITDVEELGKWMSDHMSAHPMFERVPEAELTKDPVVPLLYTGTEEGQKVERNSGSTFLNVFRRVANPNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXG4</accession>
    <name>A4RXG4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MPT family transporter: inner membrane translocase (Import) Tim22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_94294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417996.1">
        <property type="nucleotide sequence ID" value="XM_001417959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXG4"/>
    <dbReference type="STRING" id="436017.A4RXG4"/>
    <dbReference type="GeneID" id="5001746"/>
    <dbReference type="Gramene" id="ABO96289">
        <property type="protein sequence ID" value="ABO96289"/>
        <property type="gene ID" value="OSTLU_94294"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94294"/>
    <dbReference type="eggNOG" id="KOG3225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091077_2_0_1"/>
    <dbReference type="OMA" id="VNPNMAD"/>
    <dbReference type="OrthoDB" id="75343at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="200" mass="20821" checksum="F170D4FDA651BD4C" modified="2007-05-15" version="1">MDASSASVTRDDASSTLETSTSEVTAGEVDGELRAATATPGEKKKKKKKTYERVKLPTPEDVYQQDAMDNCAIKTVMSCVLGGALGGVMGVVFGAFEPMEVPAPDAPKVTMRETIRQGAKSAGARSWSYAKGFAAFGALYAGSECVVEKVRAKHDVANSAYAGCFTGGVMARTSGPTGMAVGCATMAALSVAMDKFMDHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXK1</accession>
    <name>A4RXK1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_31722</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418011.1">
        <property type="nucleotide sequence ID" value="XM_001417974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXK1"/>
    <dbReference type="GeneID" id="5001711"/>
    <dbReference type="Gramene" id="ABO96304">
        <property type="protein sequence ID" value="ABO96304"/>
        <property type="gene ID" value="OSTLU_31722"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31722"/>
    <dbReference type="eggNOG" id="ENOG502QSRD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1158032_0_0_1"/>
    <dbReference type="OMA" id="HQNLIEM"/>
    <dbReference type="OrthoDB" id="4644at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183:SF6">
        <property type="entry name" value="CYSTEINE SULFINATE DESULFINASE_CYSTEINE DESULFURASE AND RELATED ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="26144" checksum="004B2E1D286D1866" modified="2007-05-15" version="1">MTRGARERDARARAGARDETSVSRDAGDVGDRGRETTRGGPREDLEGLFGADYSGDGLSTQGEAVVKGVAAVEDKPSGMTLDVDYLQELIAIQEDCPKEIGFFGTRNMGFMHQQLIEILAYALCLTGNHIYTSGATGTNAAVIRGALRAEQPELLTVVLPQSLAKQPRESRELLEGVAQIVEAPENDGMPLVEASRICNDTIVSKVKQIIVFAFHDSRLLLETCRNAKTMRKLVTLFYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXR7</accession>
    <name>A4RXR7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DEAD/DEAH box helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_31789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417802.1">
        <property type="nucleotide sequence ID" value="XM_001417765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXR7"/>
    <dbReference type="STRING" id="436017.A4RXR7"/>
    <dbReference type="GeneID" id="5001775"/>
    <dbReference type="Gramene" id="ABO96095">
        <property type="protein sequence ID" value="ABO96095"/>
        <property type="gene ID" value="OSTLU_31789"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31789"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_3_1"/>
    <dbReference type="OMA" id="NGDMLMK"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="15"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="226"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="373"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="47563" checksum="35147945BE08609C" modified="2007-05-15" version="1">MNIVEPTEIQTKAIDVIGRGAGNAFVASHTGSGKTLAYLLPVIQRMKAAEIAAGDRLAKPKRPKVVVACPTRELAEQVAEVAKALSHVAKFSSYLVVGGRRLGTQKERLDSAIDVVIGTPGRLIKHVDQGNLFLGSVDAMVLDEADTLFEAGFGDEVKRLLRPLKARPEGKTCVLVSATMPDRLKKLVDEELPALQYIKTDSLHRSAPGLKHRFVDCPGDVDKMTVLEQIVAPEHKQGKKLMIFCNTLPSCIAVERTMFEADIRTVQYHGDMTSDARADAMREFIDADADENLTMVCTDLAARGLDFGRVKVDHVVNFDFPMNSLDYIHRSGRTARAGAGGKVTNLVAKKDRVLASEIDNAVKLGLPIDNATSSRAVSEARKKKSIADARDRRTGGRSRAKPSTVRDSKPSNRGRRGAARFTTDDTKTKPSNRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXV9</accession>
    <name>A4RXV9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein BCCIP homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_38561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BCP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417821.1">
        <property type="nucleotide sequence ID" value="XM_001417784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXV9"/>
    <dbReference type="STRING" id="436017.A4RXV9"/>
    <dbReference type="GeneID" id="5001714"/>
    <dbReference type="Gramene" id="ABO96114">
        <property type="protein sequence ID" value="ABO96114"/>
        <property type="gene ID" value="OSTLU_38561"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38561"/>
    <dbReference type="eggNOG" id="KOG3034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068770_0_0_1"/>
    <dbReference type="OMA" id="NFTHILG"/>
    <dbReference type="OrthoDB" id="27543at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025602">
        <property type="entry name" value="BCP1_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261">
        <property type="entry name" value="BRCA2 AND CDKN1A INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261:SF0">
        <property type="entry name" value="BRCA2 AND CDKN1A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13862">
        <property type="entry name" value="BCCIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028983">
        <property type="entry name" value="BCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="31135" checksum="5B8CC5240BB4CDD4" modified="2007-05-15" version="1" fragment="single">DGERREDAREGDEGAARKADDDCDSCIDKQVDFDFCDVQEGDFHGLKALLSGYCDGNEYACSDLCDLLIKQKAVGTVVKTEADSENVLGVTSVVSLARHKDEKCVKDIKKFLLGKVPGKSKKDFEKVLNDAATGLLINERIINVPQDAGEPLIDGVFDEIRWATKDETTEEARKSYEFKHYILVSTLFEEDGEEEAEPAAGKKRKKGQPTRQKIFPRLEEEILLEHSTNSFFWRGKQNEENDIADFLPHRCCMVVEARVIDAFRKDVKDLFQDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYE9</accession>
    <name>A4RYE9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GST C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_15658</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418372.1">
        <property type="nucleotide sequence ID" value="XM_001418335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYE9"/>
    <dbReference type="STRING" id="436017.A4RYE9"/>
    <dbReference type="GeneID" id="5002432"/>
    <dbReference type="Gramene" id="ABO96665">
        <property type="protein sequence ID" value="ABO96665"/>
        <property type="gene ID" value="OSTLU_15658"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15658"/>
    <dbReference type="eggNOG" id="KOG2903">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037263_1_0_1"/>
    <dbReference type="OMA" id="PWANRAI"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01148">
        <property type="entry name" value="Xi_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="185"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="139"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="157"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="38408" checksum="3D5E9D04035EF26D" modified="2007-05-15" version="1">MDRTAVADVSPTGAFARKASTFRNAFDANGAHPPEAHRYVLVVSLACPWATRCLAALRAKGLEDVLDVAVTHPVWGKTRPNDPNDAHAGWRFVKPGTVVTGPSGRGAFEADARCSATACEGAEFVRDLYEICGAPTEQRFTVPLIWDTLRKTIVNNESSEILRELNTKFQDFCSSDAAREVDLYPEHLRPKIDEINQWVYDDINNGVYKCGFAVSQSAYDEAVKNLFSALDRCEELLARSRYIAGDVFTEADVRLFMTLIRFDEVYVVYFKTNKKFIHQYEHMGAYVRELYQMPALRRATDFAHIKQHYFASHPSLNPHAIVPCGPNVDLDAAHGRDGPYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYJ1</accession>
    <name>A4RYJ1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_40865</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418402.1">
        <property type="nucleotide sequence ID" value="XM_001418365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYJ1"/>
    <dbReference type="STRING" id="436017.A4RYJ1"/>
    <dbReference type="GeneID" id="5002358"/>
    <dbReference type="Gramene" id="ABO96695">
        <property type="protein sequence ID" value="ABO96695"/>
        <property type="gene ID" value="OSTLU_40865"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40865"/>
    <dbReference type="eggNOG" id="KOG4284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
    <dbReference type="OMA" id="WRDREAN"/>
    <dbReference type="OrthoDB" id="434041at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17943">
        <property type="entry name" value="DEADc_DDX20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="9">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="68"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="258"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="407" mass="44353" checksum="4C1E8ECC10B0296B" modified="2007-05-15" version="1" fragment="single">MPRASPRARSSDVALRDDTSTDARAGANVGERATSSASFGDLQLDERLTRALRAAGFDAPSPVQLACVPLGRFGCDVIAQAKSGTGKTMTFVVIALERVDAGRRRTQALALAPTRECAVQTHECFVEMIEKFKDMDGDARGGIETCLLVGGLPVKEDRARLASQPHVVVGTPGRTRQMLEEGSMACDGARLLILDEADALLSGTFERDVLFAYSMLPERKQVCAFSATYSKTLLGDLERLMRAPQKVMLCESTTALQGVRQFYSLIEKEDGTKLADVITAKEARLLKICGDVSFHQAVVFVRRLAWGEALAKRLTSQGLKAAFTAGTLPQERRMKVMEEMRNFQLRVLVSTDLTARGVDLTHVNLVINLDVPPSGATYMHRIGRTGRFGTYGLAVAVLTADELEQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYN6</accession>
    <name>A4RYN6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 11</fullName>
            <shortName evidence="5">U3 snoRNA-associated protein 11</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_32092</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the UTP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418423.1">
        <property type="nucleotide sequence ID" value="XM_001418386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYN6"/>
    <dbReference type="STRING" id="436017.A4RYN6"/>
    <dbReference type="GeneID" id="5002555"/>
    <dbReference type="Gramene" id="ABO96716">
        <property type="protein sequence ID" value="ABO96716"/>
        <property type="gene ID" value="OSTLU_32092"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32092"/>
    <dbReference type="eggNOG" id="KOG3237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061887_0_2_1"/>
    <dbReference type="OMA" id="ERSQPKW"/>
    <dbReference type="OrthoDB" id="495000at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015952">
        <property type="entry name" value="U3snoRNP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="237"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="266" mass="30699" checksum="FB9E571F16DB62D1" modified="2007-05-15" version="1">MSSSLRNAVKRKTHKERSQLSERKRFGLLEKKKDYVLRARDYHKKEDAINALKRKAAYRNPDEFYFAMQKAKTDDGVHVARSTEQNKYTEEELRVMKTQDVKYVQMKAAIEGKKVEKMKRNLHGIGVPVKRKHTVFVDTEEEAKSFDAAEHFDTVPELVNRTFNRPRRAQLEDEDAVVGVRSDGAAGSSGTGASEISMKRLTRMQKGAYKTYTAYDERAKKLKDMSAEMAMQKVISHSKGHKVKITKTNPDGTKTSYFKWKQERQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYP6</accession>
    <name>A4RYP6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_10584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418429.1">
        <property type="nucleotide sequence ID" value="XM_001418392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYP6"/>
    <dbReference type="STRING" id="436017.A4RYP6"/>
    <dbReference type="GeneID" id="5002222"/>
    <dbReference type="Gramene" id="ABO96722">
        <property type="protein sequence ID" value="ABO96722"/>
        <property type="gene ID" value="OSTLU_10584"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10584"/>
    <dbReference type="eggNOG" id="KOG0191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_2_1"/>
    <dbReference type="OMA" id="EYEKDRT"/>
    <dbReference type="OrthoDB" id="74910at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF11">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="81" mass="9399" checksum="187EFFA5B6545D65" modified="2007-05-15" version="1" fragment="single">VVELTPENFEREVTRREGAVFVEFYAPWCPYCKRLEPIWEELPEKLEEAGSKTRVARMNVDAYADYASAYAVTGFPTLMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYU2</accession>
    <name>A4RYU2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_15766</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UTP23/FCF1 family. FCF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418221.1">
        <property type="nucleotide sequence ID" value="XM_001418184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYU2"/>
    <dbReference type="STRING" id="436017.A4RYU2"/>
    <dbReference type="GeneID" id="5002403"/>
    <dbReference type="Gramene" id="ABO96514">
        <property type="protein sequence ID" value="ABO96514"/>
        <property type="gene ID" value="OSTLU_15766"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15766"/>
    <dbReference type="eggNOG" id="KOG3165">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081098_0_1_1"/>
    <dbReference type="OMA" id="CICERVR"/>
    <dbReference type="OrthoDB" id="76105at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09864">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000004">
        <property type="entry name" value="rRNA-processing protein FCF1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037503">
        <property type="entry name" value="Fcf1_PIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="PIN" evidence="7">
        <location>
            <begin position="69"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO96514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="200" mass="22926" checksum="A978CD153E4C245F" modified="2007-05-15" version="1">MGKNRLKTKQFAAVKRMINPKDIAKQRKGADKSGESNKRKNRDEIKLKRVETQSSALFGKYNALLKPPYNVIVDTNFINFSIKNKIDLMKGMMDCLYAECVPHITDCVMAELEKLGQKYRVALRIAKDPRFERLPCSHKGTYADDCICERVRQHRCYIVATCDTDLKRRIRKIPGVPIMFMGNHKYTIERLPDAGGIGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYU5</accession>
    <name>A4RYU5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ras-related protein Rab-21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_32150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418223.1">
        <property type="nucleotide sequence ID" value="XM_001418186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYU5"/>
    <dbReference type="STRING" id="436017.A4RYU5"/>
    <dbReference type="GeneID" id="5002404"/>
    <dbReference type="Gramene" id="ABO96516">
        <property type="protein sequence ID" value="ABO96516"/>
        <property type="gene ID" value="OSTLU_32150"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32150"/>
    <dbReference type="eggNOG" id="KOG0088">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_10_2_1"/>
    <dbReference type="OMA" id="NDEQHRN"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032482">
        <property type="term" value="P:Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04123">
        <property type="entry name" value="Rab21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000550">
        <property type="entry name" value="ras-related protein Rab-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041833">
        <property type="entry name" value="Rab21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="177"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="214" mass="22635" checksum="BB33734B2E9B52B8" modified="2007-05-15" version="1">MTGAQSASNAFKVVLLGEGRVGKTSLLLRYVENTFSETQTPTVQATYLSKRVALENDGAATLNVWDTAGQERFHALGPIYYRDADAAVLVYDITDSDSFDRVKSWVKELRQIAGSEISLAVCANKSDLERARKVSQSDGETYAKSIGAAFFSTSAKADKGVAQAFMSVATALDAKRGKSAAGGGGAGTKTSGVGRSRSLKIAEEEMKPRGGDCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ08</accession>
    <name>A4RZ08_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA polymerase II-associated protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_92909</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RPAP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418489.1">
        <property type="nucleotide sequence ID" value="XM_001418452.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RZ08"/>
    <dbReference type="GeneID" id="5002502"/>
    <dbReference type="Gramene" id="ABO96782">
        <property type="protein sequence ID" value="ABO96782"/>
        <property type="gene ID" value="OSTLU_92909"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92909"/>
    <dbReference type="eggNOG" id="KOG4732">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_247896_0_0_1"/>
    <dbReference type="OMA" id="LIAPWME"/>
    <dbReference type="OrthoDB" id="497229at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055326">
        <property type="entry name" value="MINIYO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013929">
        <property type="entry name" value="RPAP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013930">
        <property type="entry name" value="RPAP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47605">
        <property type="entry name" value="TRANSCRIPTIONAL ELONGATION REGULATOR MINIYO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47605:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL ELONGATION REGULATOR MINIYO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08620">
        <property type="entry name" value="RPAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08621">
        <property type="entry name" value="RPAP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RPAP1 N-terminal" evidence="4">
        <location>
            <begin position="211"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="RPAP1 C-terminal" evidence="3">
        <location>
            <begin position="297"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="913"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1518" mass="161636" checksum="0DA4E85C5E08D875" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ59</accession>
    <name>A4RZ59_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Myosin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_40911</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418272.1">
        <property type="nucleotide sequence ID" value="XM_001418235.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RZ59"/>
    <dbReference type="GeneID" id="5002209"/>
    <dbReference type="Gramene" id="ABO96565">
        <property type="protein sequence ID" value="ABO96565"/>
        <property type="gene ID" value="OSTLU_40911"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40911"/>
    <dbReference type="eggNOG" id="KOG0160">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000192_3_1_1"/>
    <dbReference type="OMA" id="DMTALWL"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030048">
        <property type="term" value="P:actin filament-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01384">
        <property type="entry name" value="MYSc_Myo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036018">
        <property type="entry name" value="MYSc_Myo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF781">
        <property type="entry name" value="MYOSIN-15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6 9" id="KW-0518">Myosin</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Myosin motor" evidence="13">
        <location>
            <begin position="5"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="12">
        <location>
            <begin position="1089"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="9">
        <location>
            <begin position="565"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="991"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="852"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="925"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="99"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1453" mass="163305" checksum="035684ADA40C584C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="117" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZZ6</accession>
    <name>A4RZZ6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ABC(ABCC) family transporter: multispecific organic anion/multidrug (ABCC)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_35503</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418885.1">
        <property type="nucleotide sequence ID" value="XM_001418848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZZ6"/>
    <dbReference type="STRING" id="436017.A4RZZ6"/>
    <dbReference type="GeneID" id="5002866"/>
    <dbReference type="Gramene" id="ABO97178">
        <property type="protein sequence ID" value="ABO97178"/>
        <property type="gene ID" value="OSTLU_35503"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35503"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_1_1"/>
    <dbReference type="OMA" id="MEREWYQ"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
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        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="661"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="707"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="799"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="913"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="60"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="377"/>
            <end position="599"/>
        </location>
    </feature>
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        <location>
            <begin position="666"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="984"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1218"/>
            <end position="1245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO97178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1256" mass="139094" checksum="BDD959DFD84C0136" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0R2</accession>
    <name>A4S0R2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine/threonine protein phosphatase 2A regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_35344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphatase 2A regulatory subunit.</text>
    </comment>
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        <property type="protein sequence ID" value="ABO97076.1"/>
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    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ABO97076"/>
        <property type="gene ID" value="OSTLU_35344"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35344"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OMA" id="DECQREF"/>
    <dbReference type="OrthoDB" id="10264446at2759"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM-like"/>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
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    </dbReference>
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        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="429" mass="49923" checksum="685DEFADFB959D8A" modified="2007-05-15" version="1">MEVLYDKNKPLFLFRDVPVNERAALFGKKLQLCSYCFDFTDPAIDAREKEIKRQTLIEIVDYVNQGTGRFTEQVLEHINFMLAQNLFRTLPPTSSEQTGLVNAAMFDPEEEEPSLEPSWPHLQIVYEFLLRYVVSNDIDIKNGKTYIDQSFVLRLLELFDSEDPRERDYLKTILHRIYGKFMIHRPFIRQAINNIFFRFIYETEKHNGIAELLEILGSIINGFALPLKDEHKTFLKRALLPLHKPKCVGMYHSQLVYCVTQFVEKDPRMADVVIRGLLKYWPVTNSQKEVLILGELEEVLELTQSAQFANVMVPLFKQISFCINSTHFQVAERALFLWNNDYIVNLVAQHRHALLPVCFGALEKNAVGHWNPVVGGLTINVRKMLQEMDPELFAQCRERWLADQERLAEDEKARQARWSRVERLAGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S116</accession>
    <name>A4S116_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_6675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419074.1">
        <property type="nucleotide sequence ID" value="XM_001419037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S116"/>
    <dbReference type="STRING" id="436017.A4S116"/>
    <dbReference type="GeneID" id="5003357"/>
    <dbReference type="Gramene" id="ABO97367">
        <property type="protein sequence ID" value="ABO97367"/>
        <property type="gene ID" value="OSTLU_6675"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6675"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058290_0_0_1"/>
    <dbReference type="OMA" id="VECQSEV"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd08774">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="3">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="25994" checksum="D2B5CEFE7E911612" modified="2007-05-15" version="1" fragment="single">ESLVFSAKLSQQCGRDEDMLGSMRTLAATCDEELTDEERNLFSVALKNVLQSLRSSIAVAKAMELRERQLANDDGAALAKGYAQKLSAELSRFCSSTIEAIERRLSTPTESSAHARVFYLKLLGDYWRYTCEVDIDADKRDEAIAHCTDAYEVGVELAATSGLTMCDPIRLGLYLNQTVFLYEIVGKHSGAIAISNACVCAFESAREAIGVADVADVGEAMADAEAIVQLMRNNCVLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S131</accession>
    <name>A4S131_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DEK-C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_32956</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419292.1">
        <property type="nucleotide sequence ID" value="XM_001419255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S131"/>
    <dbReference type="STRING" id="436017.A4S131"/>
    <dbReference type="GeneID" id="5003364"/>
    <dbReference type="Gramene" id="ABO97585">
        <property type="protein sequence ID" value="ABO97585"/>
        <property type="gene ID" value="OSTLU_32956"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32956"/>
    <dbReference type="eggNOG" id="KOG2266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_807380_0_0_1"/>
    <dbReference type="OMA" id="KTPFPDR"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000779">
        <property type="term" value="P:regulation of double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044198">
        <property type="entry name" value="DEK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468">
        <property type="entry name" value="DEK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468:SF1">
        <property type="entry name" value="PROTEIN DEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEK-C" evidence="6">
        <location>
            <begin position="352"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="228"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="236"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="300"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="409" mass="44813" checksum="5AEC158FF8DB5901" modified="2007-05-15" version="1">MDAPTPDAPAATAPTPAPASPSVKPKRERKKVEVFQVVDDAPKKSLDVKPGRGTKLCEIPNVAFKLSKIPRKEELLKFVYRILYKGVGKQQTIKRDIGEFSGWTFENDGERAVKEDLLSRAFKDTLHDLLDLFELPRGSGAEGKKEAQVARLMTWLDAPKASGKKSLEEAEAKKRAAKEKKRERTAKKTAAKAKKTAAAKSSAGGSAKQAALIKKLKAENAALRAKIAKLTGKEEEPAEEEEEEEEEEEEEDEEDEEDEDEDEEDEEEEEEEDSDEEFTEKPAAKKPKPAPKPAKQQSPSPEPSPEPSPVKAPSPAKAPTPAPAPPAPKTEPPKPVEPTPAPAPAAEPTNPPPTAAELGSAVRRLLVNADMEQVSMKSVRKDLETKFGMSLSDRKEEIKRLVTEFLESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1K9</accession>
    <name>A4S1K9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">OSTLU_42764</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419168.1">
        <property type="nucleotide sequence ID" value="XM_001419131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1K9"/>
    <dbReference type="STRING" id="436017.A4S1K9"/>
    <dbReference type="GeneID" id="5003453"/>
    <dbReference type="Gramene" id="ABO97461">
        <property type="protein sequence ID" value="ABO97461"/>
        <property type="gene ID" value="OSTLU_42764"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42764"/>
    <dbReference type="eggNOG" id="KOG0731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_16_2_1"/>
    <dbReference type="OMA" id="NIMREGR"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010304">
        <property type="term" value="P:PSII associated light-harvesting complex II catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF56">
        <property type="entry name" value="INACTIVE ATP-DEPENDENT ZINC METALLOPROTEASE FTSHI 2, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="95"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABO97461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="560" mass="61545" checksum="6BB1306C5846A706" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1S2</accession>
    <name>A4S1S2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Possible psbZ, PSII-Z, photosystem II polypeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">psbZ</name>
        <name evidence="1" type="ORF">OSTLU_33201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419197.1">
        <property type="nucleotide sequence ID" value="XM_001419160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1S2"/>
    <dbReference type="STRING" id="436017.A4S1S2"/>
    <dbReference type="GeneID" id="5003111"/>
    <dbReference type="Gramene" id="ABO97490">
        <property type="protein sequence ID" value="ABO97490"/>
        <property type="gene ID" value="OSTLU_33201"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33201"/>
    <dbReference type="HOGENOM" id="CLU_193307_0_0_1"/>
    <dbReference type="OMA" id="XAKYRRE"/>
    <dbReference type="OrthoDB" id="419533at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010206">
        <property type="term" value="P:photosystem II repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.810">
        <property type="entry name" value="Photosystem II Pbs27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025585">
        <property type="entry name" value="PSII_Psb27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038450">
        <property type="entry name" value="PSII_Psb27_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34041">
        <property type="entry name" value="PHOTOSYSTEM II REPAIR PROTEIN PSB27-H1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34041:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REPAIR PROTEIN PSB27-H1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13326">
        <property type="entry name" value="PSII_Pbs27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="84" mass="9533" checksum="62DD6F7F7EACC759" modified="2007-05-15" version="1">MAPGTEGREESINTTRNMTNAWVAKYRRDNKTTGKPSYGQVYSALNAVSGHFNNFGTKYPFPAKRKDRVFAEFEQAELLLSRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1V3</accession>
    <name>A4S1V3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419213.1">
        <property type="nucleotide sequence ID" value="XM_001419176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1V3"/>
    <dbReference type="GeneID" id="5003210"/>
    <dbReference type="Gramene" id="ABO97506">
        <property type="protein sequence ID" value="ABO97506"/>
        <property type="gene ID" value="OSTLU_33232"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33232"/>
    <dbReference type="HOGENOM" id="CLU_2201433_0_0_1"/>
    <dbReference type="OrthoDB" id="45963at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="108" mass="12265" checksum="53B75AF8EFD3A359" modified="2007-05-15" version="1">MSATRESTDAERAQTNDDGFESSDDEQYVVKPIDVSTMSISERRAQRFKDCFWDLEAKLARWFGLEDSRYEFELSVREEEDERAAAEAAREEAKKDAAARAAEDGTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S267</accession>
    <name>A4S267_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_9923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419696.1">
        <property type="nucleotide sequence ID" value="XM_001419659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S267"/>
    <dbReference type="STRING" id="436017.A4S267"/>
    <dbReference type="GeneID" id="5003633"/>
    <dbReference type="Gramene" id="ABO97989">
        <property type="protein sequence ID" value="ABO97989"/>
        <property type="gene ID" value="OSTLU_9923"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9923"/>
    <dbReference type="eggNOG" id="KOG0167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114384_3_1_1"/>
    <dbReference type="OMA" id="ANISWWI"/>
    <dbReference type="OrthoDB" id="10064100at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16664">
        <property type="entry name" value="RING-Ubox_PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000442">
        <property type="entry name" value="RING-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045185">
        <property type="entry name" value="PUB22/23/24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045210">
        <property type="entry name" value="RING-Ubox_PUB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22849:SF164">
        <property type="entry name" value="U-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22849">
        <property type="entry name" value="WDSAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="6">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="68" mass="7869" checksum="AD92ECCE017C03F9" modified="2007-05-15" version="1" fragment="single">EIPAHFQCPITMELMQDPVMIATGHTYDRPAIQRWLDQGHRTCPVTGVRLRHLELIPNHAIRTAIQSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S293</accession>
    <name>A4S293_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PA14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419708.1">
        <property type="nucleotide sequence ID" value="XM_001419671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S293"/>
    <dbReference type="GeneID" id="5003529"/>
    <dbReference type="Gramene" id="ABO98001">
        <property type="protein sequence ID" value="ABO98001"/>
        <property type="gene ID" value="OSTLU_33370"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33370"/>
    <dbReference type="HOGENOM" id="CLU_1148843_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.182.10">
        <property type="entry name" value="Toxin - Anthrax Protective Antigen,domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671848" description="PA14 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="2">
        <location>
            <begin position="40"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="242" mass="25005" checksum="3558233A31E4319B" modified="2007-05-15" version="1">MSLRARARLFLIALVVARVRFAAAAIDIANTSTVSSSVPVDARGLRLDVFTYPVAPTRVPDVRGAAPAHTANVTSIDVSSLPLASGQTVDANALARFRGRLRANVTGAHLFALEANAGGALRVNGGVVASSESGGNITGWKYLEANVDVEIEAITYNGASGTFSAKLYWRAPLSAALAVVPAEHFYASADSCCSCKCGTKPCRVSSDQAVVECFDVVDTSGVSSATAATSLESIFGVTTPYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2A3</accession>
    <name>A4S2A3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_6704</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419496.1">
        <property type="nucleotide sequence ID" value="XM_001419459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2A3"/>
    <dbReference type="STRING" id="436017.A4S2A3"/>
    <dbReference type="GeneID" id="5003588"/>
    <dbReference type="Gramene" id="ABO97789">
        <property type="protein sequence ID" value="ABO97789"/>
        <property type="gene ID" value="OSTLU_6704"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6704"/>
    <dbReference type="eggNOG" id="KOG0820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041220_0_1_1"/>
    <dbReference type="OMA" id="RHEHGQN"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF27">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="8">
        <location>
            <begin position="15"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="268" mass="30419" checksum="98399877DB9696E8" modified="2007-05-15" version="1" fragment="single">ARRWLGQHFLVDASVVTDAVEAARLGAGERVLEIGPGTGNLTNEMLKRGARVLAVEKDRNLAEKLREGLCVEYKDAFELVEGDFLKWDGLATAFERATPETPRAKVVANIPYNITTDVLKVLLPMGDTFEDMIFMFQEEVAQRLVRDDAGGGDYRAMSVRVHYYSKPYYIRPVLRDCFMPPPNVESCLIGFKPKEPHELLPLNGTDKQFFTFVQACFAQKRKMLRNNLKAVCDEATMDGAFALLDRGLKVRPQELTMEEYVKLFNFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2E7</accession>
    <name>A4S2E7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone deacetylase complex subunit SAP30 Sin3 binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_33429</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419519.1">
        <property type="nucleotide sequence ID" value="XM_001419482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2E7"/>
    <dbReference type="STRING" id="436017.A4S2E7"/>
    <dbReference type="GeneID" id="5003738"/>
    <dbReference type="Gramene" id="ABO97812">
        <property type="protein sequence ID" value="ABO97812"/>
        <property type="gene ID" value="OSTLU_33429"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33429"/>
    <dbReference type="eggNOG" id="ENOG502QSKD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1139601_0_0_1"/>
    <dbReference type="OMA" id="NISACVE"/>
    <dbReference type="OrthoDB" id="498664at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024145">
        <property type="entry name" value="His_deAcase_SAP30/SAP30L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038291">
        <property type="entry name" value="SAP30_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025718">
        <property type="entry name" value="SAP30_Sin3-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13286:SF6">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30L-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13286">
        <property type="entry name" value="SAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13867">
        <property type="entry name" value="SAP30_Sin3_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase complex subunit SAP30 Sin3 binding" evidence="8">
        <location>
            <begin position="184"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="244" mass="26859" checksum="2780CECA09141E5E" modified="2007-05-15" version="1">MDAECGEEEEGSDGDAREEDQGNKTNARKRGRKPKAANEEGARGDADAEASLPKRTEVTITGNARTKAELIGMKGVVKKSLPSGGWHRLVLENGREVRVRRSALTASETGRGDEEGEQGEDDDDEDDEDEDDGDDKDNMATRARRPTRVPGNGPPSQAAAAAMKRLQERRRSARPNCQSNFERLTLSTLQKYKKAYEMEANPETDGDKNALVHEVGKHFMQQKLDEQKVLQAFMCAVADTTQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2I4</accession>
    <name>A4S2I4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-acyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_50433</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419536.1">
        <property type="nucleotide sequence ID" value="XM_001419499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2I4"/>
    <dbReference type="GeneID" id="5003654"/>
    <dbReference type="Gramene" id="ABO97829">
        <property type="protein sequence ID" value="ABO97829"/>
        <property type="gene ID" value="OSTLU_50433"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50433"/>
    <dbReference type="eggNOG" id="KOG1315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027721_2_1_1"/>
    <dbReference type="OMA" id="NCYSSFP"/>
    <dbReference type="OrthoDB" id="496365at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="128"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="331" mass="36654" checksum="1F9E02C23FFF19BB" modified="2007-05-15" version="1">MASPARRTRETDDATVNAMGGDRNVFASRACDACRALGSFMVLVVLAIVGLTYYATVVVVYGPLAAEGGEDAGVATGALCAYHVFAFMLLWSYFACVLTAPGDVPRGWTPAPEDPEEAASEAKKSNSEKRRRFCKKCAAWKPTRTHHCSVCKRCVLKMDHHCVWVANCVGAYNYKFFLQFLAYTFLATVLDAILLLSNFIDFFKDVDPAEGTELAVVFVTFIVNVAFSASLLGFLVMHGNLILSNMTTIEMYEKKKTLPWKYDLGRFRNFKEVFGENVFMWFLPVHSSSHLEKMRVNTGISDGECLEGAAYARACESAQREATIGNRKGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S322</accession>
    <name>A4S322_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_7001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419842.1">
        <property type="nucleotide sequence ID" value="XM_001419805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S322"/>
    <dbReference type="STRING" id="436017.A4S322"/>
    <dbReference type="GeneID" id="5003509"/>
    <dbReference type="Gramene" id="ABO98135">
        <property type="protein sequence ID" value="ABO98135"/>
        <property type="gene ID" value="OSTLU_7001"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7001"/>
    <dbReference type="eggNOG" id="KOG0102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_0_2_1"/>
    <dbReference type="OMA" id="KEDCFYA"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="25158" checksum="0563182C4E6B9E24" modified="2007-05-15" version="1" fragment="single">ICGIDLGTTNSAVAIVRDGRAEIVPCQGLRTIPSVVALGPDGAVTVGVEAKKRMQKDSRNALHSVKRFIGRKYKKCKAQAKDVPYRVVPHPETKFAAIAAVDESGEEYLVLPEEASAHVLRTLLDAAEAELGTTIDKAVITVPAYFDDLQMEATTRAGHLAGLNVVRLLKEPVAAALAYGVDVDEDETVFVFDLGGGTFDVSVLEVGGGTVEVLATGGDPNLGGDDFDRIIAVWLASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S323</accession>
    <name>A4S323_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed DNA polymerase family A palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_50562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419843.1">
        <property type="nucleotide sequence ID" value="XM_001419806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S323"/>
    <dbReference type="STRING" id="436017.A4S323"/>
    <dbReference type="GeneID" id="5003845"/>
    <dbReference type="Gramene" id="ABO98136">
        <property type="protein sequence ID" value="ABO98136"/>
        <property type="gene ID" value="OSTLU_50562"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50562"/>
    <dbReference type="eggNOG" id="KOG0950">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004675_2_1_1"/>
    <dbReference type="OrthoDB" id="2320933at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08638">
        <property type="entry name" value="DNA_pol_A_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000002">
        <property type="entry name" value="DNA polymerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.10">
        <property type="entry name" value="Taq DNA Polymerase, Chain T, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="DNA POLYMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133:SF62">
        <property type="entry name" value="DNA POLYMERASE THETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="2">
        <location>
            <begin position="176"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="460" mass="51945" checksum="A9AB8F1C0E8BD690" modified="2007-05-15" version="1">MEIEMPFVAPIVAMQTVRIPFDARKMREEMATMDDRLKKLEEYALTQKWIVLDSSVSIARRALTNNTYLQDRLYKHLKLTPPPGAKTSIDANNLRKLYEQSNHPFPLLIIEHRSVFKRRGFADTILGMYADDSRIRYSIFQTNHDCGRLAHSEPNFHSLAHDMTCGDQFYGLDAPKISIRSAFVPPAAKVFVRADYSQLELRIMAHFSGDRTLIHMLQNPEPNNLKDDPFTMLASKWYRKAPDTVLAEERTNCKNLVYGLLYGSGAKKLASDLRMCEEAAKSEVARFKSMLPRLMEWLDGIVIRAREEKPIARVTTISARHRYFPDLHSKNNDDRAAAERQAVNTVCQGSAADIFKTAVVRVIDTLRTKYLIERCQLVLTVHDECVFECDARSAKAIAQIVRHAMESVANEFNLAVPLPVKVQIGSSLGDDAFAVVPRPSSRLPSAANTPAQSPIKSRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S376</accession>
    <name>A4S376_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_94776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419665.1">
        <property type="nucleotide sequence ID" value="XM_001419628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S376"/>
    <dbReference type="STRING" id="436017.A4S376"/>
    <dbReference type="GeneID" id="5003875"/>
    <dbReference type="Gramene" id="ABO97958">
        <property type="protein sequence ID" value="ABO97958"/>
        <property type="gene ID" value="OSTLU_94776"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94776"/>
    <dbReference type="eggNOG" id="ENOG502RZYB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1858622_0_0_1"/>
    <dbReference type="OMA" id="ELGPNDC"/>
    <dbReference type="OrthoDB" id="513375at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009534">
        <property type="term" value="C:chloroplast thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048564">
        <property type="term" value="P:photosystem I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15852">
        <property type="entry name" value="PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15852:SF56">
        <property type="entry name" value="PROTEIN PHOTOSYSTEM I ASSEMBLY 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="14797" checksum="B7494A7531784CAD" modified="2007-05-15" version="1">MSSSGVVAEPANAELGPNDCLECGGRGVVACDMCGGTGKWKALNRKRSKDTYEFTECPQCFGRGIRVCPVCFGTGERNVKGLLRRTEATELVKAMQRGELRPGDVQALIEEGRSMNTERGGFDAAPAPAKPAAQREFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3G0</accession>
    <name>A4S3G0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-ketoglutarate-dependent dioxygenase AlkB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_26042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420089.1">
        <property type="nucleotide sequence ID" value="XM_001420052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3G0"/>
    <dbReference type="SMR" id="A4S3G0"/>
    <dbReference type="STRING" id="436017.A4S3G0"/>
    <dbReference type="GeneID" id="5004226"/>
    <dbReference type="Gramene" id="ABO98382">
        <property type="protein sequence ID" value="ABO98382"/>
        <property type="gene ID" value="OSTLU_26042"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26042"/>
    <dbReference type="eggNOG" id="ENOG502S5VN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053054_0_0_1"/>
    <dbReference type="OMA" id="MFANCQD"/>
    <dbReference type="OrthoDB" id="545910at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="3">
        <location>
            <begin position="220"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="426" mass="46976" checksum="A392D87F2E3FBDA6" modified="2007-05-15" version="1">MRAARGHHPARCTARAHRIARRRRVVARRADASDRETAAAPSAAQLVNDAKSALDILTAADSLPLPTDASLAPHESQLHHRRKRKKTCSRALQRLAKMLVGTRREDARREATSATQFARLVAGALWIDDDDETRNDPEAGVLFTETARALGSLAPFEMEEAARVNFYATAAAATLPPRCATVVAWALARCGSAVPNEVDIAMRGVPFRFQPYLTAGLIDLETLKREVPFKREQLTTRDGRRVDERRETCWMGEEHVGSYAYSGKIMQPVPMCPAVARVRDALEEKTGERFDCCLINLYPSETAACAYHTDPFMGIGYATDSIIVSVGETRRFSFRPLGSTDAESHWIRTLDGDAIWMFANCQDDFEHCVMTAEGDGNDAPRASIVFKRSLKRKSAAEARAKKKKKKPPPSSSGGAGGGRKQPAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3H3</accession>
    <name>A4S3H3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-acyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_38073</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419917.1">
        <property type="nucleotide sequence ID" value="XM_001419880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3H3"/>
    <dbReference type="GeneID" id="5004249"/>
    <dbReference type="Gramene" id="ABO98210">
        <property type="protein sequence ID" value="ABO98210"/>
        <property type="gene ID" value="OSTLU_38073"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38073"/>
    <dbReference type="eggNOG" id="KOG1311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_205489_2_0_1"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="3"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="52" mass="6291" checksum="CD5F3F96BB7FCFF9" modified="2007-05-15" version="1" fragment="single">MINNRYCKTCHCARPLRSKHCPFCNRCVEKMDHHCPITMTCIGARNQRWFFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3M4</accession>
    <name>A4S3M4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Selenoprotein F/M domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419947.1">
        <property type="nucleotide sequence ID" value="XM_001419910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3M4"/>
    <dbReference type="GeneID" id="5003986"/>
    <dbReference type="Gramene" id="ABO98240">
        <property type="protein sequence ID" value="ABO98240"/>
        <property type="gene ID" value="OSTLU_26104"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26104"/>
    <dbReference type="HOGENOM" id="CLU_3072074_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="53" mass="5738" checksum="E3CB8417DB3F928D" modified="2007-05-15" version="1">MSPTLTMYEDAASDNNGIDVDVGSWSSDVIVEYLKSKLTPSPDASSRSSRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3X5</accession>
    <name>A4S3X5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Domain of unknown function at the cortex 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420169.1">
        <property type="nucleotide sequence ID" value="XM_001420132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3X5"/>
    <dbReference type="GeneID" id="5004036"/>
    <dbReference type="Gramene" id="ABO98462">
        <property type="protein sequence ID" value="ABO98462"/>
        <property type="gene ID" value="OSTLU_94888"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94888"/>
    <dbReference type="HOGENOM" id="CLU_057228_0_0_1"/>
    <dbReference type="OMA" id="FEIWHEC"/>
    <dbReference type="OrthoDB" id="42898at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013897">
        <property type="entry name" value="Duc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826:SF2">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08588">
        <property type="entry name" value="Duc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Domain of unknown function at the cortex 1" evidence="2">
        <location>
            <begin position="2"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="28648" checksum="7FBAE1D1FFCE4011" modified="2007-05-15" version="1">MEFETELFRGKIVCRFKGVEDAHTKTSSEFYRVKKCTFQVLVQGKFKEKVKVSDMLTGGEFDRAFENIPPRTLVFAGEQFFKLLTPGLSVDMLCDVPYYYAPLGSTLSVLAAHAEEDAPEPTAEIGEDTRRFGGRFATPKTIDERCAIFSDPSENEEYYFNTEDVYTMDYFQNVLLFDEYVLDVKVTQLPLARCLNGQPISFFGKHRDGRYAYSFEIWHECLLPKAPERTPIGTPWPQSDHRERPSPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S439</accession>
    <name>A4S439_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxidoreductase molybdopterin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420028.1">
        <property type="nucleotide sequence ID" value="XM_001419991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S439"/>
    <dbReference type="STRING" id="436017.A4S439"/>
    <dbReference type="GeneID" id="5004177"/>
    <dbReference type="Gramene" id="ABO98321">
        <property type="protein sequence ID" value="ABO98321"/>
        <property type="gene ID" value="OSTLU_26273"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26273"/>
    <dbReference type="eggNOG" id="ENOG502SY2Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_467245_0_0_1"/>
    <dbReference type="OMA" id="YVEGRYN"/>
    <dbReference type="OrthoDB" id="498163at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43032:SF4">
        <property type="entry name" value="OXIDOREDUCTASE MOLYBDOPTERIN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43032">
        <property type="entry name" value="PROTEIN-METHIONINE-SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672138" description="Oxidoreductase molybdopterin-binding domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidoreductase molybdopterin-binding" evidence="2">
        <location>
            <begin position="438"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="601" mass="66776" checksum="D4D2D499C000D5E3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S462</accession>
    <name>A4S462_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ApaG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420215.1">
        <property type="nucleotide sequence ID" value="XM_001420178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S462"/>
    <dbReference type="STRING" id="436017.A4S462"/>
    <dbReference type="GeneID" id="5003940"/>
    <dbReference type="Gramene" id="ABO98508">
        <property type="protein sequence ID" value="ABO98508"/>
        <property type="gene ID" value="OSTLU_17180"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17180"/>
    <dbReference type="eggNOG" id="KOG4408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059101_0_0_1"/>
    <dbReference type="OMA" id="RYMFAYH"/>
    <dbReference type="OrthoDB" id="2305498at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1470">
        <property type="entry name" value="ApaG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050718">
        <property type="entry name" value="ApaG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007474">
        <property type="entry name" value="ApaG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036767">
        <property type="entry name" value="ApaG_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003967">
        <property type="entry name" value="PRK05461.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47191">
        <property type="entry name" value="OS05G0170800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47191:SF2">
        <property type="entry name" value="OS05G0170800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04379">
        <property type="entry name" value="DUF525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110069">
        <property type="entry name" value="ApaG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51087">
        <property type="entry name" value="APAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApaG" evidence="1">
        <location>
            <begin position="79"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="221" mass="24495" checksum="720C2F1C8AAAAD33" modified="2007-05-15" version="1">MRLDERLADAIACENFAAAANVRDELRALRRRDPLARAEDDLAELILREDYEKAASVKMLIEELERDAVVDGLSPCESDRTTRGVRVRVKSRCVIDRSSPKESMWFFQYVVTITNVSDSSVKLLSRSWLITDDEGRTEAVRGAGVVGKQPTIKPGASFEYASSTPLKTKRGTMEGFYRFVAVDAEEASRAESVTMDLAREDDPSAFNVEIGVFGLSESATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4V5</accession>
    <name>A4S4V5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="4">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_44388</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="4"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420502.1">
        <property type="nucleotide sequence ID" value="XM_001420465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4V5"/>
    <dbReference type="STRING" id="436017.A4S4V5"/>
    <dbReference type="CAZy" id="GH77">
        <property type="family name" value="Glycoside Hydrolase Family 77"/>
    </dbReference>
    <dbReference type="GeneID" id="5004512"/>
    <dbReference type="Gramene" id="ABO98795">
        <property type="protein sequence ID" value="ABO98795"/>
        <property type="gene ID" value="OSTLU_44388"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44388"/>
    <dbReference type="eggNOG" id="ENOG502QR3V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014132_0_0_1"/>
    <dbReference type="OMA" id="HYEFKED"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010297">
        <property type="term" value="F:heteropolysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000025">
        <property type="term" value="P:maltose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32518">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32518:SF3">
        <property type="entry name" value="4-ALPHA-GLUCANOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="729" mass="84031" checksum="0DF50B2D943A4D79" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4X7</accession>
    <name>A4S4X7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_44289</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420346.1">
        <property type="nucleotide sequence ID" value="XM_001420309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4X7"/>
    <dbReference type="STRING" id="436017.A4S4X7"/>
    <dbReference type="GeneID" id="5004398"/>
    <dbReference type="Gramene" id="ABO98639">
        <property type="protein sequence ID" value="ABO98639"/>
        <property type="gene ID" value="OSTLU_44289"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44289"/>
    <dbReference type="eggNOG" id="KOG4750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_0_1_1"/>
    <dbReference type="OMA" id="SYTHAFC"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000002">
        <property type="entry name" value="Serine acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="entry name" value="serine acetyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053376">
        <property type="entry name" value="Serine_acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041874">
        <property type="entry name" value="EPS_EpsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42811">
        <property type="entry name" value="SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00971">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine acetyltransferase N-terminal" evidence="7">
        <location>
            <begin position="13"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="28915" checksum="795DB56CDA65716D" modified="2007-05-15" version="1">MASTSKSPRDDPIWTSLRAGAQALVDKEPLMGGFVYATILNQPTFERALGFLLASKIANATILAGQWNDLIMDAMNATNEGKNREYNGPGTGSIGDAARADLKAIVERDPACPSYTHAFCFFKGFQGLQAQRVAHWLWGHQRKVLACKMQSLISEVYGMDLHPAARFGRGIMIDHGHGVVVGETAVVDDDCTLLHGVTLGGTGKVRGDRHPKLGKRVVVGSNASVLGNIKVGHDCKIGAGAALMHDLPPRTTVVGHKGRVVTKKQITSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5G0</accession>
    <name>A4S5G0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiaminase-2/PQQC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_88734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420767.1">
        <property type="nucleotide sequence ID" value="XM_001420730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5G0"/>
    <dbReference type="STRING" id="436017.A4S5G0"/>
    <dbReference type="GeneID" id="5004686"/>
    <dbReference type="Gramene" id="ABO99060">
        <property type="protein sequence ID" value="ABO99060"/>
        <property type="gene ID" value="OSTLU_88734"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88734"/>
    <dbReference type="eggNOG" id="ENOG502QQU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077537_3_0_1"/>
    <dbReference type="OMA" id="FVHQMAT"/>
    <dbReference type="OrthoDB" id="10028886at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050967">
        <property type="entry name" value="Thiamine_Salvage_TenA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198">
        <property type="entry name" value="BIFUNCTIONAL TH2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198:SF2">
        <property type="entry name" value="SI:CH1073-67J19.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="1">
        <location>
            <begin position="7"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="195" mass="22038" checksum="48E74A24A6249155" modified="2007-05-15" version="1">MTASGSFVHQMATGELPREKYLRYLSQDAYFLFHFNRAYAQALRLAADVDEQRVFHELIGGVLDELKLHSAACEKWGVDVDAVEVHAASRAYVEFLESLHGKSSLELVAGMIPCMRLYAYVGRYFLTRADAGVDGIPDPRTSPYAEWFEAYGGDEMESLACRLESLLPEEIEDERAVDNYVEAIRLERDFFAAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5N5</accession>
    <name>A4S5N5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_39469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420641.1">
        <property type="nucleotide sequence ID" value="XM_001420604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5N5"/>
    <dbReference type="GeneID" id="5004759"/>
    <dbReference type="Gramene" id="ABO98934">
        <property type="protein sequence ID" value="ABO98934"/>
        <property type="gene ID" value="OSTLU_39469"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39469"/>
    <dbReference type="eggNOG" id="KOG2382">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046770_0_0_1"/>
    <dbReference type="OMA" id="QETWAFN"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="51"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="306" mass="33487" checksum="9F6E290589ACA6E7" modified="2007-05-15" version="1">MSFFTAAVRRVVNHRRRALTRAFSDHARVLAHEVHGAPFGSKVDADASSTIFILHGLLGAGRNWRSFAKQLRQRLGEQDWRVVLVDLRGHGASASIGQRTPACGVVEAARDVDALAKMIGTAPSVVVGHSLGGKVALEYSKLATTAPKQTWSLDSVPGRVEADPHGVAEVLSAIRALPRRIPSRKWLAQALPQFSTELVDWIGSNLKNVCDGGSELELVFNLDTVMQLYDSYQKTDSWHAIEDEASGIYVVKAENSTRWSTACVERLKRSPANFQVLANAGHWVHTDNPNGLLEILTTSIPKSRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5P9</accession>
    <name>A4S5P9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420809.1">
        <property type="nucleotide sequence ID" value="XM_001420772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5P9"/>
    <dbReference type="GeneID" id="5004908"/>
    <dbReference type="Gramene" id="ABO99102">
        <property type="protein sequence ID" value="ABO99102"/>
        <property type="gene ID" value="OSTLU_17602"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17602"/>
    <dbReference type="HOGENOM" id="CLU_971107_0_0_1"/>
    <dbReference type="OrthoDB" id="10430981at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="287" mass="31825" checksum="EC1C44D0330B9476" modified="2007-05-15" version="1">MATMISQKNALLFTAATGFGYGLQFMPELPSASTDRANAFGELTELPLRAFAQPMMKYYGLKSTVISDFMMHATGIMLLTSMVALVYVARTQSEPTLHRFTFAQMIGCFSRITVMSCHGAKSRIGGLQVTKELAMGSKVGLLTFILLAESQRGTTRLTPMRNFITDSKTVKQKIIAASLLMELYYMLMLHFGDATVAGWFSSKIKATDYIAIHWTATIGFLRWMGTMKMFTILPEESLGTVAKFHAVDNLMNLYMMRKHAAAFKAAEFTKHFTMGVARLGATLFAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5V3</accession>
    <name>A4S5V3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_26893</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420834.1">
        <property type="nucleotide sequence ID" value="XM_001420797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5V3"/>
    <dbReference type="STRING" id="436017.A4S5V3"/>
    <dbReference type="GeneID" id="5004696"/>
    <dbReference type="Gramene" id="ABO99127">
        <property type="protein sequence ID" value="ABO99127"/>
        <property type="gene ID" value="OSTLU_26893"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26893"/>
    <dbReference type="eggNOG" id="KOG0017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_941320_0_0_1"/>
    <dbReference type="OMA" id="AFETTEY"/>
    <dbReference type="OrthoDB" id="543346at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01114">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053926">
        <property type="entry name" value="RecX_HTH_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053924">
        <property type="entry name" value="RecX_HTH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="REGULATORY PROTEIN RECX FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602:SF1">
        <property type="entry name" value="REGULATORY PROTEIN RECX FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21982">
        <property type="entry name" value="RecX_HTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX_HTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecX first three-helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="RecX second three-helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="33791" checksum="12A2486CCD650D9D" modified="2007-05-15" version="1">MFLTFVRTACARPLAPAERLTHAEATPRRLKLDSSQSATTTSFPSRTRGFALRTRAQANADDASEVPRKKTRADVFESLKNQPLSGTKYKSTGAFQPTRVDDAKAQIVRFLEYKPRTRKELFDKLTIDKGYEAEDANEALDAMQRAGVQSDAAYAEAFARYKWRNSRWAAWRVRGALRQKGVDDRDIDLGFGPVFAEGGAIKIDLFEDDEDDDEDDDEDDEENLERTRAKELLQAARTQFKRNKRGDFQARVRRLMAWLERRGHGGSVIRDIVTVLKREEEYSDDDEDDGALHFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="118" xmlns="https://uniprot.org/uniprot">
    <accession>A4S645</accession>
    <name>A4S645_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA topoisomerase 2</fullName>
            <ecNumber evidence="13">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_41836</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="13"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420882.1">
        <property type="nucleotide sequence ID" value="XM_001420845.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4S645"/>
    <dbReference type="GeneID" id="5005057"/>
    <dbReference type="Gramene" id="ABO99175">
        <property type="protein sequence ID" value="ABO99175"/>
        <property type="gene ID" value="OSTLU_41836"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41836"/>
    <dbReference type="eggNOG" id="KOG0355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001935_1_0_1"/>
    <dbReference type="OMA" id="TWTQDFK"/>
    <dbReference type="OrthoDB" id="276498at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
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        <source>
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        <source>
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    <sequence length="1292" mass="145370" checksum="C38CE668EA96BA46" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6B9</accession>
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        <recommendedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="5" type="primary">SDG3517</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">CCE9901</strain>
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        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
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        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
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        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
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        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
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    </evidence>
    <sequence length="813" mass="90602" checksum="B79CEB32C380D047" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-07-13" modified="2025-04-09" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Y4</accession>
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        <recommendedName>
            <fullName evidence="1">Lon protease homolog, mitochondrial</fullName>
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    </protein>
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        <name type="ORF">OSTLU_41620</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer or homoheptamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421175.1">
        <property type="nucleotide sequence ID" value="XM_001421138.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422780.1">
        <property type="nucleotide sequence ID" value="XM_001422743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6Y4"/>
    <dbReference type="SMR" id="A4S6Y4"/>
    <dbReference type="STRING" id="436017.A4S6Y4"/>
    <dbReference type="EnsemblPlants" id="ABO99468">
        <property type="protein sequence ID" value="ABO99468"/>
        <property type="gene ID" value="OSTLU_41620"/>
    </dbReference>
    <dbReference type="EnsemblPlants" id="ABP01139">
        <property type="protein sequence ID" value="ABP01139"/>
        <property type="gene ID" value="OSTLU_52138"/>
    </dbReference>
    <dbReference type="GeneID" id="5005054"/>
    <dbReference type="GeneID" id="5006932"/>
    <dbReference type="Gramene" id="ABO99468">
        <property type="protein sequence ID" value="ABO99468"/>
        <property type="gene ID" value="OSTLU_41620"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01139">
        <property type="protein sequence ID" value="ABP01139"/>
        <property type="gene ID" value="OSTLU_52138"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41620"/>
    <dbReference type="KEGG" id="olu:OSTLU_52138"/>
    <dbReference type="eggNOG" id="KOG2004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004109_1_0_1"/>
    <dbReference type="OMA" id="WLTNIPW"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070407">
        <property type="term" value="P:oxidation-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000021">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000001">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1480:FF:000002">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000015">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03120">
        <property type="entry name" value="lonm_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027503">
        <property type="entry name" value="Lonm_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0720">Serine protease</keyword>
    <keyword id="KW-0809">Transit peptide</keyword>
    <feature type="transit peptide" description="Mitochondrion" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000395768" description="Lon protease homolog, mitochondrial">
        <location>
            <begin position="41"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="3">
        <location>
            <begin position="112"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="2">
        <location>
            <begin position="748"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="838"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="881"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="507"/>
            <end position="514"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="936" mass="101688" checksum="7BCF7680ABE28B8E" modified="2007-05-15" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Z6</accession>
    <name>A4S6Z6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="4">2.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PYR2</name>
        <name evidence="13" type="ORF">OSTLU_19816</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation of carbamoyl phosphate and aspartate to form carbamoyl aspartate and inorganic phosphate, the committed step in the de novo pyrimidine nucleotide biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421183.1">
        <property type="nucleotide sequence ID" value="XM_001421146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6Z6"/>
    <dbReference type="STRING" id="436017.A4S6Z6"/>
    <dbReference type="GeneID" id="5005371"/>
    <dbReference type="Gramene" id="ABO99476">
        <property type="protein sequence ID" value="ABO99476"/>
        <property type="gene ID" value="OSTLU_19816"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19816"/>
    <dbReference type="eggNOG" id="KOG0370">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043846_1_1_1"/>
    <dbReference type="OMA" id="VLIMHPG"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1370:FF:000002">
        <property type="entry name" value="Aspartate carbamoyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002032">
        <property type="entry name" value="PRK00856.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753:SF6">
        <property type="entry name" value="ASPARTATE CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753">
        <property type="entry name" value="ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00101">
        <property type="entry name" value="ATCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase carbamoyl-P binding" evidence="12">
        <location>
            <begin position="55"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase Asp/Orn-binding" evidence="11">
        <location>
            <begin position="202"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="355" mass="38847" checksum="E79036F3F8B4FA5F" modified="2007-05-15" version="1">MARASVAPARGDVAARRRSARRAARGRVGASRRVARDATRDATYASGLATLESCVEAEQFDRAMMEELFDVADAMERVRPGAPESTMLQGYLMSTLFYEPSTRTRLSFEAAMGRLGGGIVSTESAGEYSSAAKGETLEDTMRTVEGYADIVVLRHFTAGSARRAANAIGKPLINAGDGPGQHPTQALLDVYTIRKEIGRLDDFKIALVGDLANGRTVRSLASALTQFNNVKFYFVAPDVVKMKDDIKDLLTSKGIEWEEATDLAAVAADVDVLYQTRIQKERFANPEDYAKASGKYIVDRTIMDALPKSSVVMHPLPRVDEIVVDVDDDPRAGYFRQAQNGLFIRMALLKVLLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S702</accession>
    <name>A4S702_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421370.1">
        <property type="nucleotide sequence ID" value="XM_001421333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S702"/>
    <dbReference type="GeneID" id="5005554"/>
    <dbReference type="Gramene" id="ABO99663">
        <property type="protein sequence ID" value="ABO99663"/>
        <property type="gene ID" value="OSTLU_25460"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25460"/>
    <dbReference type="HOGENOM" id="CLU_786172_0_0_1"/>
    <dbReference type="OMA" id="MQSKRED"/>
    <dbReference type="OrthoDB" id="498873at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021503">
        <property type="entry name" value="DUF3110"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11360">
        <property type="entry name" value="DUF3110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="353" mass="39725" checksum="9490FD0FAFEE32A6" modified="2007-05-15" version="1">MARRWPSEKTMKRAKAARAEATEIRRRRDARRDAAKRAEEWKERVRVKGGEGEEASEGDAERARLDAELAARARAKEAREKKAPMPGASAQWTPADEYLNSILRKESAAHPVDDAEVVRNAEVESSPRTNAREAPREPEYPPELVEAMKRMEADIASGAFSEEALLEKYADVLDTFGEEFDPVNIDDDDDKGEHPQLLDPYWWRDARALHLIMITPMGSRDSRLFAMQMVPDNIPPRARPEDKFHVLAFENKSDAENFCFFMQSKREDEDLDDALRGLVTMTGIGPKELQKVADDAGYGVTVVGAGRVDLSANRPHVDVLNHITHIGGEVYLWEFARKVKRDFDAENGGAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S776</accession>
    <name>A4S776_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytidyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25512</name>
        <name evidence="1" type="ORF">OSTLU_51418</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421407.1">
        <property type="nucleotide sequence ID" value="XM_001421370.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421438.1">
        <property type="nucleotide sequence ID" value="XM_001421401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S776"/>
    <dbReference type="GeneID" id="5005302"/>
    <dbReference type="GeneID" id="5005340"/>
    <dbReference type="Gramene" id="ABO99700">
        <property type="protein sequence ID" value="ABO99700"/>
        <property type="gene ID" value="OSTLU_51418"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99731">
        <property type="protein sequence ID" value="ABO99731"/>
        <property type="gene ID" value="OSTLU_25512"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25512"/>
    <dbReference type="KEGG" id="olu:OSTLU_51418"/>
    <dbReference type="eggNOG" id="ENOG502QTA1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026547_0_0_1"/>
    <dbReference type="OMA" id="GCYFVVG"/>
    <dbReference type="OrthoDB" id="5591297at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285:SF0">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="45922" checksum="377D9FC33BFF60C8" modified="2007-05-15" version="1">MEPGIRAIVETIHASKVRAVLHVTGGGARALGWLTSVPRCSNTLLDARVPYARESALETLGRATDDDVESYCSREVAEALASAAYARAVRHGSSRATASASDARATTGLGATCALTTEDVVKRGDHRCFVAAKTLGRMTTYEMRLEKTSGRSRFDEEGCASRLVLRALYEEARRSVDDADADAGVDLVREVLSEREFDEVSVTTMEDSAYANASDARAVVERWLAEDDSSTSGATTAAPMILEFTGGVLTAVGATRANVVLSGSFNPLHDGHRDLLAAATATKPPGALGAYEIGVTNADKGTLSIDEIMRRLEQFSTPGTVCLLTKTPLFVDKTRAAPGAAFVVGADTAARLLDPKYAGSDAALDESLNEIRANACDFLVAGRVDRVSRAFVPAADVLAAAAARRAADLFAALPSFRVDVSSTEIRNAARDSGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7D7</accession>
    <name>A4S7D7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NAD(+) kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_43339</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421435.1">
        <property type="nucleotide sequence ID" value="XM_001421398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7D7"/>
    <dbReference type="STRING" id="436017.A4S7D7"/>
    <dbReference type="GeneID" id="5005368"/>
    <dbReference type="Gramene" id="ABO99728">
        <property type="protein sequence ID" value="ABO99728"/>
        <property type="gene ID" value="OSTLU_43339"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43339"/>
    <dbReference type="eggNOG" id="KOG2178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008831_10_0_1"/>
    <dbReference type="OMA" id="AFVVTEM"/>
    <dbReference type="OrthoDB" id="24581at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000009">
        <property type="entry name" value="Poly(P)/ATP NAD kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF6">
        <property type="entry name" value="NAD KINASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34137" checksum="B3830BD429D19467" modified="2007-05-15" version="1">MDELANADILEDTLHRAVVLKNAEKLRKVDGIIPQEDWGTTDIIVCLGGDGVILHASKLFQGPVPPLLGFHFGSLGFLTSHPSDEMASSLLQSIGRGKPVVNIQGGVPITLRMRLECTLVKAKDKIGSGGTGEFTKKITVLNELLVDRGPSPYLSQIEAYDRGELITTIQADGVIVATATGSTAYSVSAGGSMVHPNVPAILMTPICPHTLSFRPVIFPDSVEIELRVAQDARCSAWVSFDGRDRCELESGDSVFVRMSQYPIPTINYADQTGDFINSLRRCLRWNERDMQHAFDASQKEALRKISEAESNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7E7</accession>
    <name>A4S7E7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">PsaH, PSI-H, subunit VI, photosystem I polypeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">psaH</name>
        <name evidence="12" type="ORF">OSTLU_9089</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Possible role could be the docking of the LHC I antenna complex to the core complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the psaH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421439.1">
        <property type="nucleotide sequence ID" value="XM_001421402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7E7"/>
    <dbReference type="STRING" id="436017.A4S7E7"/>
    <dbReference type="GeneID" id="5005568"/>
    <dbReference type="Gramene" id="ABO99732">
        <property type="protein sequence ID" value="ABO99732"/>
        <property type="gene ID" value="OSTLU_9089"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9089"/>
    <dbReference type="HOGENOM" id="CLU_152855_1_0_1"/>
    <dbReference type="OMA" id="KWDLYGS"/>
    <dbReference type="OrthoDB" id="496139at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004928">
        <property type="entry name" value="PSI_PsaH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34787">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT VI-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34787:SF1">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT VI-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03244">
        <property type="entry name" value="PSI_PsaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="91" mass="9676" checksum="E319D71C42D59900" modified="2007-05-15" version="1" fragment="single">AMKTNAKYGDESVYFDLSDVEATTGSWDVYGVDASSRYPDQQAAFFEYAAQGLGRREAVYSLLAVSAGLLTVGYGVKGAKDAKLPITVGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Q1</accession>
    <name>A4S7Q1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_89178</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAPT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421310.1">
        <property type="nucleotide sequence ID" value="XM_001421273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Q1"/>
    <dbReference type="GeneID" id="5005287"/>
    <dbReference type="Gramene" id="ABO99603">
        <property type="protein sequence ID" value="ABO99603"/>
        <property type="gene ID" value="OSTLU_89178"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89178"/>
    <dbReference type="eggNOG" id="KOG2490">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003655_1_1_1"/>
    <dbReference type="OMA" id="KLYMACH"/>
    <dbReference type="OrthoDB" id="29023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008010">
        <property type="entry name" value="Tatp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317:SF4">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05346">
        <property type="entry name" value="DUF747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="460"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="488" mass="54601" checksum="A0E8D37D68B949DF" modified="2007-05-15" version="1">MEALRDWTVMREDEGRSSPPPVAIEGLTTIRKYCALELGLRVGEREDDPDMSHARERVFDLLWYIPLELEKFCLYGGLLCADAILGLFTSLPVRVMSQTVRLAWSVSGLKSRDKTSSKRRAWGIHPYAREHLNDVLWLFMLCVAVTYTHMLDVSVIYHYIRGQEVIKLYMACHVLETFDKLLCSFNSNVLDALQNSVHGCVSAATNGSKVDQVKSGVRLAVDVILSTSATVAHTFILLTHAVTLSVAINSHTNAMLLVLISNNFAEMKGHVFKKQDPEKLFGVSRLDVIERVHLCVCLMFVTAQRIMAAGNLEMALTRKFLNDIALVMGSEIFVDVVKHSFMAKFNGLRPGVYRRFYRQICRDHVHLTQSYKIHQVVGFVPLAPAAVIVRVVPGLYRTLKQNAMSSDIVTRGAFDRLLAHFSGRVIGLGVMFIAICFKLAFGIAIYTWGARSLERTSKVTPSAERWGAKTPGKVTGSMPRSPPRIKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7U8</accession>
    <name>A4S7U8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_18191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421337.1">
        <property type="nucleotide sequence ID" value="XM_001421300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7U8"/>
    <dbReference type="GeneID" id="5005421"/>
    <dbReference type="Gramene" id="ABO99630">
        <property type="protein sequence ID" value="ABO99630"/>
        <property type="gene ID" value="OSTLU_18191"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18191"/>
    <dbReference type="HOGENOM" id="CLU_702820_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="393" mass="42748" checksum="20EFC77AB4A8A130" modified="2007-05-15" version="1">MARSTRSGDATRVDALMRAVDAVADALGDAGEANHRAFRDDAERIATALERTLTRDEDADAFAVLGVEHTASMWTACVDAWTRAAETREATRATAATLRDVAAAARDAERAWAAKRARGVARELEEVELRHDARVRRGEDAARRARLVGRFRAEETAARDALGDAGEASAGVDVVARFRALEGEFLWREECVLRGERGASALEASVRAFEPDSRVGALALAVTRAARWRERVATFEGRRDDEFERRCDQDVIARMEAQHPALVAQYVMWMKDAALESSERAASSAVAAATTHLYDFLLALDADVYDAVFDAQGRANVLCASFNALHVLRSRASPSSPPPRLAADARALISRLVVRVDAERDAEIALHGDDWGQAAFAVVAARLASQRLLEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7V6</accession>
    <name>A4S7V6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GPI ethanolamine phosphate transferase 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_51391</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421518.1">
        <property type="nucleotide sequence ID" value="XM_001421481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7V6"/>
    <dbReference type="STRING" id="436017.A4S7V6"/>
    <dbReference type="GeneID" id="5005426"/>
    <dbReference type="Gramene" id="ABO99811">
        <property type="protein sequence ID" value="ABO99811"/>
        <property type="gene ID" value="OSTLU_51391"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51391"/>
    <dbReference type="eggNOG" id="KOG2126">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004298_2_1_1"/>
    <dbReference type="OMA" id="LAYHPWA"/>
    <dbReference type="OrthoDB" id="272139at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16023">
        <property type="entry name" value="GPI_EPT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037675">
        <property type="entry name" value="PIG-O_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045687">
        <property type="entry name" value="PIGG/GPI7_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039524">
        <property type="entry name" value="PIGO/GPI13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071:SF1">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19316">
        <property type="entry name" value="PIGO_PIGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="529"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="GPI ethanolamine phosphate transferase 2 C-terminal" evidence="12">
        <location>
            <begin position="499"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO99811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="645" mass="70359" checksum="6263211E9C797DD6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Z9</accession>
    <name>A4S7Z9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_27676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421541.1">
        <property type="nucleotide sequence ID" value="XM_001421504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Z9"/>
    <dbReference type="GeneID" id="5005446"/>
    <dbReference type="Gramene" id="ABO99834">
        <property type="protein sequence ID" value="ABO99834"/>
        <property type="gene ID" value="OSTLU_27676"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27676"/>
    <dbReference type="eggNOG" id="ENOG502QQTP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_850843_0_0_1"/>
    <dbReference type="OMA" id="LVIQWIF"/>
    <dbReference type="OrthoDB" id="202063at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="37930" checksum="746F99AB2F93F0AA" modified="2007-05-15" version="1">MNADGLTENTTPTPAMDARERDATTRAIVETRTTSSRQKTSTAGALVRALGRWKPMKTPKTTGTLMLYCLGIYVAFYARAPVEITPTMQRRYDDALRRVDEEIGEALRRVSSSYYDAERELRAVTPFGWRFTATPSQRSRIEQAKKRQRDAARALRVEERKRDAAMREARSELGLWSELGVGDAKALFKRSYERGKVFATRSTFWDGLHLMLRGKSDESTISFLLRWAFIAVSNFTMGMLSAIFSYAFALPGLISSFSTSIWSGVAFFLVALVSAVSVVASVLALLYGGAAGGTFALVKYAGPALARLDEAEDRRRARIGQRAAYGNYAHQNARQRYHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S817</accession>
    <name>A4S817_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL4c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">50S ribosomal protein L4, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRPL4</name>
        <name evidence="9" type="ORF">OSTLU_40690</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421683.1">
        <property type="nucleotide sequence ID" value="XM_001421646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S817"/>
    <dbReference type="STRING" id="436017.A4S817"/>
    <dbReference type="GeneID" id="5005789"/>
    <dbReference type="Gramene" id="ABO99976">
        <property type="protein sequence ID" value="ABO99976"/>
        <property type="gene ID" value="OSTLU_40690"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40690"/>
    <dbReference type="eggNOG" id="KOG1624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_5_2_1"/>
    <dbReference type="OMA" id="SMFFMTE"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009547">
        <property type="term" value="C:plastid ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008266">
        <property type="term" value="F:poly(U) RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_uL4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF17">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="251" mass="26343" checksum="1BF45BD42B33A4D3" modified="2007-05-15" version="1">MRSSAALQGTTAITSPRPIAGKRGANARVAPVVPRAAAIDAVTFDGAKSSAATLELKTARAEVARGLVHKYVVMVRQNARRGTASTLTKSEVRGGGRKPFKQKGTGNARAGSSRTPLKPGGGVSFGPKPRDWSIKMNKKERRLAMATALQSAASAMIVVDDISGNISAPGTNAFNKSLMAWGVGASEKAYVITKDANENVAKSARNIERVVQTDVSHLNVYDILNADKVIVEASALAHISSFFGENGAAWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S825</accession>
    <name>A4S825_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_51545</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421686.1">
        <property type="nucleotide sequence ID" value="XM_001421649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S825"/>
    <dbReference type="STRING" id="436017.A4S825"/>
    <dbReference type="GeneID" id="5005659"/>
    <dbReference type="Gramene" id="ABO99979">
        <property type="protein sequence ID" value="ABO99979"/>
        <property type="gene ID" value="OSTLU_51545"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51545"/>
    <dbReference type="eggNOG" id="KOG0676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_0_2_1"/>
    <dbReference type="OMA" id="FHTTAER"/>
    <dbReference type="OrthoDB" id="503831at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.36.70:FF:000001">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="377" mass="41793" checksum="5A44B1F3B8872544" modified="2007-05-15" version="1">MADEGEVSALVCDNGSGMVKAGFAGDDAPKAVFPSIVGRPRHHGVMVGMGQKDCYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVDPAEHPVLLTEAPMNPKANREKMCQIMFETFNVPAMYVSIQAVLSLYASGRTTGIVLDCGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYMVKILTERGHSFTTSAEREIVRDIKEKLAYVAVDFDEEMAASQSSSTIEKSYELPDGQMITIGNERFRCPEVLFQPSLIGMETPGIHETTYNSIMRCDVDIRRDLYANIVLSGGTTMFPGIADRVSKELTALAPSSMKIKVVAPHERKYSVWIGGSILASLSTFQQMWIAKSEYNEAGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8T4</accession>
    <name>A4S8T4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_89355</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421813.1">
        <property type="nucleotide sequence ID" value="XM_001421776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8T4"/>
    <dbReference type="STRING" id="436017.A4S8T4"/>
    <dbReference type="GeneID" id="5005975"/>
    <dbReference type="Gramene" id="ABP00107">
        <property type="protein sequence ID" value="ABP00107"/>
        <property type="gene ID" value="OSTLU_89355"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89355"/>
    <dbReference type="eggNOG" id="KOG3710">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052570_0_0_1"/>
    <dbReference type="OMA" id="CHYDNPG"/>
    <dbReference type="OrthoDB" id="76265at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="130"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="338" mass="37858" checksum="A6969B0022E56023" modified="2007-05-15" version="1">MEARFARRVDDALGARLASRGYACVDDFLERDTADAMRRELERLADARDANETGRGGGRKYLRPNRTKFGDEHLFGKPNIYECDMHDDGTLAETKRDAAYATIWEFFRATERGMADAFRRVIPEIALRDGPDSRTVKLQVNEGRGACFPWHYDNPGAPSNRALTCILYLNPDWKPGDGGELRLQPFCGVAATIQPKHNRLAIFFSDRTLHRVTPSTAAKRYAVTVWLDADFVDPRTGASTNASELNLNAREALSDIAKTAKELARGNAQRALSRAVYADEYEASLVECMGNARGADEMLQAHYEHCRSVKKNHALKTLVDALRDYRREVEASAAEVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4S949</accession>
    <name>A4S949_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_13352</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422003.1">
        <property type="nucleotide sequence ID" value="XM_001421966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S949"/>
    <dbReference type="STRING" id="436017.A4S949"/>
    <dbReference type="GeneID" id="5006043"/>
    <dbReference type="Gramene" id="ABP00297">
        <property type="protein sequence ID" value="ABP00297"/>
        <property type="gene ID" value="OSTLU_13352"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13352"/>
    <dbReference type="eggNOG" id="KOG0937">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026996_5_0_1"/>
    <dbReference type="OMA" id="DYGYIQN"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09253">
        <property type="entry name" value="AP-4_Mu4_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14838">
        <property type="entry name" value="AP4_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="7">
        <location>
            <begin position="207"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="481" mass="53254" checksum="CAA61B202C62F998" modified="2007-05-15" version="1">MLSQFFILSPRGDALVTKDFRRDLPRRTHETFYRTVRAWARSRRREDGEEDAEESAMGEHSREYSGAPAVFREDGVNYAHVKASGLYFVATTTRNASGSVILELLHRLARLVKDYCGALTEDAVRKNATLVYEVIDEAMDYGYAQTTSTEMLRERVCNEPVEIGGGLAGMLAAINLMNAASVASGVNRVSSSATQKSVVSASSATTRDEIFVDIIEKVNVTFNANGDVVTSEINGHIQVRNFLQGEDTKVKLALSEDLTIGGKGASAGGAYTGVILDDCNFHETANLDQFDIDRTISLRPPQGEFSLMHYRSADDFKPPFRIVPIIDESVPYKVGIELKLYADFNAKHTCTGCIVTLPIPKGAIGATARLPKHVTASTQHVMYDAAEKQIVWQFKKLPGGSDHECSVQISLQSERIPNVRREIGPLSLTFQIPTFSASDLAVRYLQVVGSSNEPRHRDDPPRNPHRWIRYMTKSSSYVVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A4S976</accession>
    <name>A4S976_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422014.1">
        <property type="nucleotide sequence ID" value="XM_001421977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S976"/>
    <dbReference type="GeneID" id="5005917"/>
    <dbReference type="Gramene" id="ABP00308">
        <property type="protein sequence ID" value="ABP00308"/>
        <property type="gene ID" value="OSTLU_28104"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28104"/>
    <dbReference type="HOGENOM" id="CLU_1919859_0_0_1"/>
    <dbReference type="OrthoDB" id="10583888at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="14714" checksum="F281AF3E680CDD82" modified="2007-05-15" version="1">MFAANAAPRAVANRRATTPRRSRKRITTIASATRTPEARATEAQRWIDAWKSGETKANETPVAKTPGESARELRDGELAIKKGLLGSFIKEGSKEVTAEDYRKFQAEIAAKKAEAQRKMKEARANKKGPFGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9P3</accession>
    <name>A4S9P3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_28268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422205.1">
        <property type="nucleotide sequence ID" value="XM_001422168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9P3"/>
    <dbReference type="STRING" id="436017.A4S9P3"/>
    <dbReference type="GeneID" id="5006161"/>
    <dbReference type="Gramene" id="ABP00522">
        <property type="protein sequence ID" value="ABP00522"/>
        <property type="gene ID" value="OSTLU_28268"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28268"/>
    <dbReference type="eggNOG" id="KOG0010">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024293_4_0_1"/>
    <dbReference type="OMA" id="PGMDMFG"/>
    <dbReference type="OrthoDB" id="267397at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14399">
        <property type="entry name" value="UBA_PLICs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000001">
        <property type="entry name" value="Ubiquilin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23195">
        <property type="entry name" value="UBQLN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="406"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="47402" checksum="D7CBA00063ED2E1D" modified="2007-05-15" version="1">MSTIALHFKRANGAKITLEDVDATTLTVRDARARVAARLAESDATIDASANVRLIFKGRVLRDEATLAACGCANESVVHVVTSTTTTTTTTTTTAATATATAAATAATAIGGRGTATASDAPFGGFGGGGAALGGSGALDLMNNPFVRSQMEALLSERPETLREMMESQPGMREAMAANPELASALTDPETLRRMMNTMTNPSLMAEQMRNNDRAMSNIEMMPGGFNALRRMYTDVQAPMERAAERDMDAAAPTATRTVNPDEPLPNPWGGAGGGAGGGGAAMPPAGGGFSMGGIGGGAGASQIEQMAEMMQNPQMRAAMDSVMSNPQMLESMLNMHPQARQMMEANPQMRETLSNPEFLRQMMNPENLRAMAQMQQLFGDAMPGGGLGGGLGGSMFAPPVAPAGPPEEVYASQLSQLNDMGFFSQEENIRALQATGGNVHAAVERLLSNPGGGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9U3</accession>
    <name>A4S9U3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">VIC family transporter: potassium ion channel subfamily G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_18703</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422231.1">
        <property type="nucleotide sequence ID" value="XM_001422194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9U3"/>
    <dbReference type="STRING" id="436017.A4S9U3"/>
    <dbReference type="GeneID" id="5006185"/>
    <dbReference type="Gramene" id="ABP00548">
        <property type="protein sequence ID" value="ABP00548"/>
        <property type="gene ID" value="OSTLU_18703"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18703"/>
    <dbReference type="eggNOG" id="KOG1419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_600775_0_0_1"/>
    <dbReference type="OMA" id="DAIYWSF"/>
    <dbReference type="OrthoDB" id="498779at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001508">
        <property type="term" value="P:action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537:SF254">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="VOLTAGE-GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="185"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="378"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="443"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABP00548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="493" mass="54004" checksum="6BA1FE2B37AD9F37" modified="2007-05-15" version="1">MAARARARVEIGARGVARDGARRARARARATATRRRDDATTATATATARRARDARDARGTRANARRRARDVRRMFFGSGTYDSFDDVDGGARGTGRENDDDDPERAAFELAEWTSQSLAKRTRDCLKLADSSGIWTVGTTALVFVIAGFESLEAEAATRGVSLEYVLPQFVPKAFAPALADGGIERAESCLQAIFLFEYVVRAWSEEFQLKYLRSPVALIDFLSLLPTFGFILSLVGIGGAGQGATEQFRPLRLFRALRLLRVLDLDGEKTRETTKREKTQNEKVVAVAVEFLCVFLISGELFYDLEVDTNPNISDVGDAIYWSFLTLTGIGQPFEATTAQGRVATVVSILTAVVVVPLQLAVLVSAQTEAQARIGEGGATLSAPPPSMAKIGLAGPPIAPKRRSPQEEEAMSTMASDFGNDFWSGTMDEDSQWLRLREREELRDARKKIKSQEISIAALRTENRKLRKALDEADLLAGLDGLELELEEDVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA42</accession>
    <name>A4SA42_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422281.1">
        <property type="nucleotide sequence ID" value="XM_001422244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA42"/>
    <dbReference type="STRING" id="436017.A4SA42"/>
    <dbReference type="GeneID" id="5006367"/>
    <dbReference type="KEGG" id="olu:OSTLU_93976"/>
    <dbReference type="eggNOG" id="ENOG502S4TE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_802525_0_0_1"/>
    <dbReference type="OMA" id="NEIHQSW"/>
    <dbReference type="OrthoDB" id="2011676at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF27">
        <property type="entry name" value="METHYLTRANSFERASE FKBM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="74"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="323" mass="35869" checksum="93E17EE9BABD595A" modified="2007-05-15" version="1" fragment="single">LLLFAACLTLFTRYRRAKLARARVEEQHSSVQPKPTRSTAPIAKDVDAAFDRAINAINADKLKRYALFDTVSRGGTQKADGWYQDNVEPAVTCAREERAGPAGEGGKGLCDPNRLRAQGADCLIYSVGSFDDFSFEEAITRDVSSAREIHAFDHTVSNPRNKPCGVHFHPLGLGGAREPDGSDLKGLADIVVALGHKGRTIDVLKIDCEGCEWSTYGSWFDADVRVDEMLVEIHAGTIDSNLNEIHQSWLSLIVGEQLFGRGALDPSREPVAKRFLRRLYDENFYIFHKEPNIKYSRLHKMCVEFALIRFDGGIEGVENSPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA75</accession>
    <name>A4SA75_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422333.1">
        <property type="nucleotide sequence ID" value="XM_001422296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA75"/>
    <dbReference type="GeneID" id="5006390"/>
    <dbReference type="Gramene" id="ABP00650">
        <property type="protein sequence ID" value="ABP00650"/>
        <property type="gene ID" value="OSTLU_25777"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25777"/>
    <dbReference type="HOGENOM" id="CLU_338424_0_0_1"/>
    <dbReference type="OrthoDB" id="500008at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="841" mass="90737" checksum="9DDA777A4F7A4D05" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAB3</accession>
    <name>A4SAB3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase Ty1/copia-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_9555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422355.1">
        <property type="nucleotide sequence ID" value="XM_001422318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAB3"/>
    <dbReference type="STRING" id="436017.A4SAB3"/>
    <dbReference type="GeneID" id="5006412"/>
    <dbReference type="Gramene" id="ABP00672">
        <property type="protein sequence ID" value="ABP00672"/>
        <property type="gene ID" value="OSTLU_9555"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9555"/>
    <dbReference type="eggNOG" id="KOG0017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001650_17_4_1"/>
    <dbReference type="OMA" id="RETHVCR"/>
    <dbReference type="OrthoDB" id="1250461at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013103">
        <property type="entry name" value="RVT_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07727">
        <property type="entry name" value="RVT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase Ty1/copia-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="103" mass="11744" checksum="59991D7EA6BC0E19" modified="2007-05-15" version="1" fragment="single">FTQVWLKDYHDTFSAVASMTTFRILINIAAILGWDIFTIDVSQAYTQGELLDDIFIKAPRSHPLPKGVVYKLKRPLYGTKQAGRCWYLHVTKTLRSIGLTQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAD4</accession>
    <name>A4SAD4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA endonuclease activator Ctp1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422367.1">
        <property type="nucleotide sequence ID" value="XM_001422330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAD4"/>
    <dbReference type="GeneID" id="5006473"/>
    <dbReference type="Gramene" id="ABP00684">
        <property type="protein sequence ID" value="ABP00684"/>
        <property type="gene ID" value="OSTLU_28530"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28530"/>
    <dbReference type="HOGENOM" id="CLU_3017635_0_0_1"/>
    <dbReference type="OrthoDB" id="5801062at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013882">
        <property type="entry name" value="Ctp1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08573">
        <property type="entry name" value="SAE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA endonuclease activator Ctp1 C-terminal" evidence="5">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="56" mass="6158" checksum="F4DCF6A5838C0BB3" modified="2007-05-15" version="1">MMPNKDRATIKCTHAPKMNGIGGDAPSNSRHRAKWAPEPAPKGFWNLAFTPPERDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SC19</accession>
    <name>A4SC19_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial splicing suppressor 51-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422960.1">
        <property type="nucleotide sequence ID" value="XM_001422923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SC19"/>
    <dbReference type="GeneID" id="5006931"/>
    <dbReference type="Gramene" id="ABP01319">
        <property type="protein sequence ID" value="ABP01319"/>
        <property type="gene ID" value="OSTLU_29812"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29812"/>
    <dbReference type="HOGENOM" id="CLU_1035838_0_0_1"/>
    <dbReference type="OMA" id="HANAYAC"/>
    <dbReference type="OrthoDB" id="502525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="1">
        <location>
            <begin position="38"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="269" mass="29330" checksum="334B70B8EE64795E" modified="2007-05-15" version="1">MLADTRKTAGSSREALRSSIVARFSEDESLMETFGPVLSIVDALERMYEEYSVTSTSGTLRIRALGASDAFELARWRTFAALAVLLENCERVEVEFIGPTLRRLYPGVVCEATSTDGSGRLRIQAIRGLYPEVSDVASASASEAAAYDVVVAFNAGLPVGGDWARAIERIVSEHVDAFAANAPSLGNVAPPFWVSDYNEEAIDIAFAFLRHVVQRVLESRNVDSRAEAIYLEPYSNAAYQSRKRISSCTVPTHANAYACAFVGLSRLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQE8</accession>
    <name>A4RQE8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FBP16-3</name>
        <name evidence="7" type="ORF">OSTLU_39771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415375.1">
        <property type="nucleotide sequence ID" value="XM_001415338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQE8"/>
    <dbReference type="STRING" id="436017.A4RQE8"/>
    <dbReference type="GeneID" id="5000017"/>
    <dbReference type="Gramene" id="ABO93667">
        <property type="protein sequence ID" value="ABO93667"/>
        <property type="gene ID" value="OSTLU_39771"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39771"/>
    <dbReference type="eggNOG" id="KOG0552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092197_0_0_1"/>
    <dbReference type="OMA" id="CRCEAAG"/>
    <dbReference type="OrthoDB" id="77911at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF17">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP16-3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="92"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="20668" checksum="695EFE1CFACE14CF" modified="2007-05-15" version="1">MARTGDDEAANAKASASAGKKCAAVVAGCAMALAMASARVAVADSLPDEVDVKVLCDAACEKRLESQEFKTTKSGLRYKEIKEGDGMEPPVGFQVVVDYIAMDEKGRIFDNSLAKGKPNDIRVVDCVGSGDFDSCTVIPGMDEGLLTMKSGGVRRLYIPGELSFPKGLASAPGRPKVPPFSPVVFDVNLLYIPGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQT0</accession>
    <name>A4RQT0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_13664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415440.1">
        <property type="nucleotide sequence ID" value="XM_001415403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQT0"/>
    <dbReference type="STRING" id="436017.A4RQT0"/>
    <dbReference type="GeneID" id="4999551"/>
    <dbReference type="Gramene" id="ABO93732">
        <property type="protein sequence ID" value="ABO93732"/>
        <property type="gene ID" value="OSTLU_13664"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13664"/>
    <dbReference type="HOGENOM" id="CLU_519133_0_0_1"/>
    <dbReference type="OMA" id="KGCPMCR"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="433" mass="47184" checksum="34FBB69B9CB62614" modified="2007-05-15" version="1">MPTAWPATGRCAVGGCGTAGEYAWARAATKWNHSGDEFAGNGSCLAIWRLRGDEATACAVFTANADRRSARGGMEEEKTLAPFARVRALDGGEGLEYVTIAINFDEEYAVLERKACAFTLDERGRTRVRAIEATSLRVDLGWMPRFGAVRGRALELAARAMPTVPSCAISSQFIVVVWLDGERPVHVIDSRAEGSTDSRRGLLEALRVNVEACLANPDAKTSRTVLDVTTYDGDAYVIVVTRDAPTPQKYAPTPREEDIHCKVFAIPTGFRSAKPSETTTETTPLIDLDDELVTRDESCTICLDVLSGEAARAPCCGASFCEDCLASYVALSAAKGCPMCRDVDVFLTSRRPHSAWGRALTSFELDLPFRARQQLKKYRVLEQVLDGDYATLDDFHLTGDRTPFALENGRALTLATSSDSNFEGVEVRELVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQY8</accession>
    <name>A4RQY8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415473.1">
        <property type="nucleotide sequence ID" value="XM_001415436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQY8"/>
    <dbReference type="STRING" id="436017.A4RQY8"/>
    <dbReference type="GeneID" id="5000013"/>
    <dbReference type="Gramene" id="ABO93765">
        <property type="protein sequence ID" value="ABO93765"/>
        <property type="gene ID" value="OSTLU_28830"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28830"/>
    <dbReference type="eggNOG" id="KOG4413">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_712482_0_0_1"/>
    <dbReference type="OMA" id="CARFPEM"/>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019538">
        <property type="entry name" value="PSMD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13554:SF10">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13554">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="388" mass="39968" checksum="B87851C6508CFBDF" modified="2007-05-15" version="1">MEEGARAAAAATRAATTRRCGEKDTGTAIAASGALLALCARFPEMLEDVLGDVLEETSREGGTSEAKVRGLAFAASAAAANEDAASVVVKSGALDACVREIDGPDLLSSLASLEILAEVAESSSAAARGLKSVGSLGDALVRATLDETADPALRTRAMIVGARIAATCATSDEALVQEMARVLTAQESNFRDAVVDAAGELCLTNAIVATNFVKTTKTVVFTAADSALRGRGESQVVALHALANVFGAERGEQEILDDEAESILADAIFAACGSKSFGDIISTALANKSDHFVNLRVAVYRLLSTAGHRARFAEEIAAHPSARDALALDVEPALVAARARRRALAALADADIADARARDLFRVAATASPRASTSRPSAVPDVLASHRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR83</accession>
    <name>A4RR83_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_39837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415854.1">
        <property type="nucleotide sequence ID" value="XM_001415817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR83"/>
    <dbReference type="STRING" id="436017.A4RR83"/>
    <dbReference type="GeneID" id="4999501"/>
    <dbReference type="Gramene" id="ABO94146">
        <property type="protein sequence ID" value="ABO94146"/>
        <property type="gene ID" value="OSTLU_39837"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39837"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_4_1"/>
    <dbReference type="OMA" id="WNMEGLG"/>
    <dbReference type="OrthoDB" id="3592703at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034256">
        <property type="term" value="F:chlorophyll(ide) b reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010304">
        <property type="term" value="P:PSII associated light-harvesting complex II catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052625">
        <property type="entry name" value="Chl_b_Red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24314:SF21">
        <property type="entry name" value="CHLOROPHYLL(IDE) B REDUCTASE NYC1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24314">
        <property type="entry name" value="NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="309" mass="33101" checksum="97C3A2ABEFD3E017" modified="2007-05-15" version="1">MTRAFARRPSAATPRAVRAPRGRARAIVRADGAARASEAQRVLITGSTRGLGYELAKSFLKRGDAVFVTSRDDDKVREVVEGLRREYGDARVAGVAADVRRAESVEAMAAACCEAFGGVDVWVNNAASNGYSYDNLEDATPEVLEEIILTNSLGSLLCTRQAIKTMKATTGRGHVFNMEGAGSDGAATRKFAAYGHTKAGMSQLAKTMAVELKDVPIGVHTISPGMVFTELISSGRDAFGSQGRMFVNALAEPAEVAAEQIVDKLKVATVSPDSVNKTIAIKILTPDVALRKMFGRFVLGENRDRFQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR91</accession>
    <name>A4RR91_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415529.1">
        <property type="nucleotide sequence ID" value="XM_001415492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR91"/>
    <dbReference type="STRING" id="436017.A4RR91"/>
    <dbReference type="GeneID" id="5000011"/>
    <dbReference type="Gramene" id="ABO93821">
        <property type="protein sequence ID" value="ABO93821"/>
        <property type="gene ID" value="OSTLU_28933"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28933"/>
    <dbReference type="eggNOG" id="ENOG502S82M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116913_0_0_1"/>
    <dbReference type="OMA" id="RCFASIT"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="17957" checksum="9BA3CBF8E6BA9013" modified="2007-05-15" version="1">MTTTTTTRPSDDVTARTLLEANGKRFDVAMPRGVALQALLLARSDDLKCVDIMCQWVGDACACRLARALDRRGEALRVLDVSGNRLRALPSAVWAMRALEVLDASDNALTPADVPFDDLMDETKDVAPNLKVLNLRGNVAVIDGLEGRLREVVDAMARRGVKLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR94</accession>
    <name>A4RR94_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_28936</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415531.1">
        <property type="nucleotide sequence ID" value="XM_001415494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR94"/>
    <dbReference type="STRING" id="436017.A4RR94"/>
    <dbReference type="GeneID" id="4999777"/>
    <dbReference type="Gramene" id="ABO93823">
        <property type="protein sequence ID" value="ABO93823"/>
        <property type="gene ID" value="OSTLU_28936"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28936"/>
    <dbReference type="eggNOG" id="KOG1142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1573268_0_0_1"/>
    <dbReference type="OrthoDB" id="2193432at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07981">
        <property type="entry name" value="HFD_TAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037794">
        <property type="entry name" value="TAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003228">
        <property type="entry name" value="TFIID_TAF12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264:SF21">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03847">
        <property type="entry name" value="TFIID_20kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 12" evidence="7">
        <location>
            <begin position="37"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO93823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="170" mass="18453" checksum="CB5792905B28F400" modified="2007-05-15" version="1">MEKRAAAQARLAAAQAAAAASAAAAKKKTDDGGHAISKDELQELLKEFAPGESFEPEVEEMLLEITDDFVDNVLEHAARLARHRGSEAVEPKDVLLHLERQWDMHIPGYGGEEVPKYTEKQSVETHSRRLAAVRRSVAAATAAQNEQRKQARLAADRATKGKGDMGAEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRN6</accession>
    <name>A4RRN6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_29082</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the amino acid/polyamine transporter 2 family. SLC38A9 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415600.1">
        <property type="nucleotide sequence ID" value="XM_001415563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRN6"/>
    <dbReference type="STRING" id="436017.A4RRN6"/>
    <dbReference type="GeneID" id="4999870"/>
    <dbReference type="Gramene" id="ABO93892">
        <property type="protein sequence ID" value="ABO93892"/>
        <property type="gene ID" value="OSTLU_29082"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29082"/>
    <dbReference type="eggNOG" id="KOG1305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037564_0_0_1"/>
    <dbReference type="OMA" id="PWAFTES"/>
    <dbReference type="OrthoDB" id="294730at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF244">
        <property type="entry name" value="NEUTRAL AMINO ACID TRANSPORTER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0458">Lysosome</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="17">
        <location>
            <begin position="47"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO93892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="467" mass="48658" checksum="695E0A853A457321" modified="2007-05-15" version="1">MAPDDVERAVPLEDDVERPLRDVASDGDDDDDDASEDARASAGDLATIFALWNTMVGSAVLAVPWAFTESGLALGAASAVVMTCAMAYTATLVLRYGARGGHDDLAGMCGAALGPRARAGCNAAMALMMAQCVVVFDMMLSTSVYGIVKGFADLAKMPATGGGGTTALAATLASSNSTGWATCTNAAKDAAKCWNPFTAVGVTAVALMCLGSLKNLDGFVAVSVLGPFFMTYLILFIVFKSVVASAPVAPIAPYANFSTFKKTAGVLSSCLFSHHAVIPVCRANSKSKNNGRNLLVAYVLALMSYLAPALAGNFSAAYVAVRRGPNGSSRAANFLRVFPPSDYYTLSAHVAVTVQFLTMVPLLLYILRTQVFGLLPQFPAKYHGAASFAVNFAAIALGSFCAAHPDIDIGMILSKCGAVFGLIFAYAAPVLVHVFGRRGNRHPLWNHIAHGTILAVGVAIALAQFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRP0</accession>
    <name>A4RRP0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromatin assembly factor 1 subunit A dimerization domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NFF3501</name>
        <name evidence="7" type="ORF">OSTLU_13904</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415603.1">
        <property type="nucleotide sequence ID" value="XM_001415566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRP0"/>
    <dbReference type="STRING" id="436017.A4RRP0"/>
    <dbReference type="GeneID" id="4999610"/>
    <dbReference type="Gramene" id="ABO93895">
        <property type="protein sequence ID" value="ABO93895"/>
        <property type="gene ID" value="OSTLU_13904"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13904"/>
    <dbReference type="eggNOG" id="KOG4364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_315778_0_0_1"/>
    <dbReference type="OrthoDB" id="79480at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="CAF1A_DD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272:SF0">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromatin assembly factor 1 subunit A dimerization" evidence="6">
        <location>
            <begin position="286"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="324"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="925" mass="101968" checksum="88E139F1E57F5E9A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS63</accession>
    <name>A4RS63_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="OSTLU_29258"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_2658957_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="76" mass="8476" checksum="D5A9548A031CA550" modified="2007-05-15" version="1">MSSTRSSAKAAPCTVSAAKRFSNAPRNQTQNQKTKNNKQLVFISTPPLQERFSTLNPNTPLARRFDDDLVVAHFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS76</accession>
    <name>A4RS76_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_29272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415694.1">
        <property type="nucleotide sequence ID" value="XM_001415657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS76"/>
    <dbReference type="GeneID" id="4999475"/>
    <dbReference type="Gramene" id="ABO93986">
        <property type="protein sequence ID" value="ABO93986"/>
        <property type="gene ID" value="OSTLU_29272"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29272"/>
    <dbReference type="eggNOG" id="ENOG502QQK6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_507500_0_0_1"/>
    <dbReference type="OMA" id="NHASWMP"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
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        <property type="entry name" value="F21O3.11 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="F21O3.11 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="105"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="550" mass="59501" checksum="58DAED2B816C4C8A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS97</accession>
    <name>A4RS97_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Archease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_40293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the archease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415706.1">
        <property type="nucleotide sequence ID" value="XM_001415669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS97"/>
    <dbReference type="STRING" id="436017.A4RS97"/>
    <dbReference type="GeneID" id="4999986"/>
    <dbReference type="Gramene" id="ABO93998">
        <property type="protein sequence ID" value="ABO93998"/>
        <property type="gene ID" value="OSTLU_40293"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40293"/>
    <dbReference type="eggNOG" id="KOG4528">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111362_3_0_1"/>
    <dbReference type="OMA" id="LTECHFL"/>
    <dbReference type="OrthoDB" id="2190767at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072669">
        <property type="term" value="C:tRNA-splicing ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.10.10">
        <property type="entry name" value="Archease domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002804">
        <property type="entry name" value="Archease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023572">
        <property type="entry name" value="Archease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036820">
        <property type="entry name" value="Archease_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12682">
        <property type="entry name" value="ARCHEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12682:SF11">
        <property type="entry name" value="PROTEIN ARCHEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01951">
        <property type="entry name" value="Archease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69819">
        <property type="entry name" value="MTH1598-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Archease" evidence="5">
        <location>
            <begin position="9"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO93998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="159" mass="18123" checksum="60C7453155E9628D" modified="2007-05-15" version="1">MRARRGVQYAYKDHTADIQIHAWGCDLAEAYAWAALAMFDYMTPLEDCARVRTTRFKEIRASGHDLDTLLFAFLDELLFTFHTEMLICTAVQVCEFNRDEWSIRAVVGGTTFVDGETRQGTEIKAITYSAMKIIERGEISKDDESTGVHRAELFVIVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSJ3</accession>
    <name>A4RSJ3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Z</name>
        <name evidence="10" type="ORF">OSTLU_119685</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416480.1">
        <property type="nucleotide sequence ID" value="XM_001416443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSJ3"/>
    <dbReference type="STRING" id="436017.A4RSJ3"/>
    <dbReference type="GeneID" id="5000342"/>
    <dbReference type="Gramene" id="ABO94773">
        <property type="protein sequence ID" value="ABO94773"/>
        <property type="gene ID" value="OSTLU_119685"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119685"/>
    <dbReference type="eggNOG" id="ENOG502QUET">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033058_0_0_1"/>
    <dbReference type="OMA" id="KGIKTQF"/>
    <dbReference type="OrthoDB" id="3366at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="entry name" value="Trigger factor ribosome-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="entry name" value="Trigger factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="TRIGGER FACTOR CHAPERONE AND PEPTIDYL-PROLYL CIS/TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560:SF3">
        <property type="entry name" value="TRIGGER FACTOR-LIKE PROTEIN TIG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="Triger factor/SurA peptide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="Trigger factor ribosome-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="Trigger factor ribosome-binding bacterial" evidence="8">
        <location>
            <begin position="74"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Trigger factor C-terminal" evidence="9">
        <location>
            <begin position="362"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="533" mass="58481" checksum="AA627F1C38A2CDB2" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSK4</accession>
    <name>A4RSK4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416226.1">
        <property type="nucleotide sequence ID" value="XM_001416189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSK4"/>
    <dbReference type="GeneID" id="5000502"/>
    <dbReference type="Gramene" id="ABO94519">
        <property type="protein sequence ID" value="ABO94519"/>
        <property type="gene ID" value="OSTLU_30215"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30215"/>
    <dbReference type="HOGENOM" id="CLU_3035771_0_0_1"/>
    <dbReference type="OMA" id="GLCAEFK"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="55" mass="6142" checksum="FE7E525D4C89FB9A" modified="2007-05-15" version="1">MSRPTTTESEPALDVDAVMTQLMDEFKRRNGREATEDEVRQWMAEISAAIAEGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSM5</accession>
    <name>A4RSM5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_48819</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416465.1">
        <property type="nucleotide sequence ID" value="XM_001416428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSM5"/>
    <dbReference type="SMR" id="A4RSM5"/>
    <dbReference type="STRING" id="436017.A4RSM5"/>
    <dbReference type="GeneID" id="5000171"/>
    <dbReference type="Gramene" id="ABO94758">
        <property type="protein sequence ID" value="ABO94758"/>
        <property type="gene ID" value="OSTLU_48819"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_48819"/>
    <dbReference type="eggNOG" id="KOG4206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041869_1_1_1"/>
    <dbReference type="OMA" id="LKKGWVM"/>
    <dbReference type="OrthoDB" id="277802at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12246">
        <property type="entry name" value="RRM1_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000039">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="10"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="149"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="220" mass="24644" checksum="3B16F33DCCF7A5B3" modified="2007-05-15" version="1">MASQVSEEFHTLYVNNLNEKVPKQELRAALHAVFSPFGKVLDIVTANTYRLRGQAWIVYDTSMDANNAMQSLQSFPFYDKPMKIVVANTTSDAIRRRRGEHIERDGAVRLSRKVENQERERLRRKNATAENATRHEPKAMDGMKRPPSTRIAVQGLPGATTTHMLALLFQQFSGYKDATMTRESGDGEVEFDTTANAVAALNGLQGFRLNANHSLTLSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSN8</accession>
    <name>A4RSN8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_44757</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416460.1">
        <property type="nucleotide sequence ID" value="XM_001416423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSN8"/>
    <dbReference type="STRING" id="436017.A4RSN8"/>
    <dbReference type="GeneID" id="5000180"/>
    <dbReference type="Gramene" id="ABO94753">
        <property type="protein sequence ID" value="ABO94753"/>
        <property type="gene ID" value="OSTLU_44757"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44757"/>
    <dbReference type="eggNOG" id="KOG1175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_6_1"/>
    <dbReference type="OMA" id="INVSYNC"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000004">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="75"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="528"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="644" mass="71045" checksum="65BB305831BF4341" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT80</accession>
    <name>A4RT80_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416362.1">
        <property type="nucleotide sequence ID" value="XM_001416325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT80"/>
    <dbReference type="GeneID" id="5000516"/>
    <dbReference type="Gramene" id="ABO94655">
        <property type="protein sequence ID" value="ABO94655"/>
        <property type="gene ID" value="OSTLU_14186"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14186"/>
    <dbReference type="HOGENOM" id="CLU_1931054_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="131" mass="14378" checksum="3236EC72CE3894DA" modified="2007-05-15" version="1">MEKYKTPFDLRVDERSFYGGEGGGDKSRAGSGGLARVGRVGVHNGQRLNQFLRDVARAAAAHKSNAAFSKELAKTGDNALKEKIHVCLVYDDGDRGERKRLSVDDGTNFGQVLSRHSPKTAFFSAHRRLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT82</accession>
    <name>A4RT82_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lhca4</name>
        <name evidence="8" type="ORF">OSTLU_24045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416356.1">
        <property type="nucleotide sequence ID" value="XM_001416319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT82"/>
    <dbReference type="STRING" id="436017.A4RT82"/>
    <dbReference type="GeneID" id="5000142"/>
    <dbReference type="Gramene" id="ABO94649">
        <property type="protein sequence ID" value="ABO94649"/>
        <property type="gene ID" value="OSTLU_24045"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24045"/>
    <dbReference type="eggNOG" id="ENOG502QSBP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057943_6_0_1"/>
    <dbReference type="OMA" id="RPCINSK"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="203" mass="22175" checksum="E7090AE2CA70A8C0" modified="2007-05-15" version="1">MWMPGATAPAHLKNELPGDYGFDPLELGKDPEDLKWYVQAELQHGRWAMLGVAGAAAPEILTNMGISNLPNWHEAPSYDGYFTDATTLFWVQMLMMNWAEVRRWQDIRKPGSVSEDPTPFSNAKLPAGVVGYPGGIFDPLGYAKGDLKTLKAKEIANGRLAMVAFAGIMVQYDHTGVGPVANLVSHMADPAHNNVFAAKFIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTC2</accession>
    <name>A4RTC2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-serine ammonia-lyase</fullName>
            <ecNumber evidence="3">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_5354</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416336.1">
        <property type="nucleotide sequence ID" value="XM_001416299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTC2"/>
    <dbReference type="STRING" id="436017.A4RTC2"/>
    <dbReference type="GeneID" id="5000166"/>
    <dbReference type="Gramene" id="ABO94629">
        <property type="protein sequence ID" value="ABO94629"/>
        <property type="gene ID" value="OSTLU_5354"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5354"/>
    <dbReference type="eggNOG" id="KOG1250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_3_0_1"/>
    <dbReference type="OMA" id="DGWVNIH"/>
    <dbReference type="OrthoDB" id="7773036at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF2">
        <property type="entry name" value="CATABOLIC L-SERINE_THREONINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="7">
        <location>
            <begin position="4"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="313" mass="32250" checksum="7C42A5397159970C" modified="2007-05-15" version="1" fragment="single">LHVRTPLVKSAPLSEIMRRDVYLKLECAQPSGSFKLRGVGRACALAVERDGARLLVSSSGGNAGLATAHAGRELGAQTVVYVPETTPERVRDALRAYGAEVEVRGTQWSEANAAATARAAACGGAMIHPFEGEDTWDGHSTMIDEIAEDLGGRKPAAVATCVGGGGLLAGCLRGIERCGWGDDVVVVAMETIGADSLNASMRAGEVVTLPAITSVAKSLGAASPSPAVFKMCVELGDARVRVRACDDAHAVAACLRFADDHRVLVEPACGAALSAAYFPELGALDGISSDPRAPIVVVVCGGSVIDRASMNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTC3</accession>
    <name>A4RTC3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_36317</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTC3"/>
    <dbReference type="STRING" id="436017.A4RTC3"/>
    <dbReference type="GeneID" id="5000077"/>
    <dbReference type="Gramene" id="ABO94392">
        <property type="protein sequence ID" value="ABO94392"/>
        <property type="gene ID" value="OSTLU_36317"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36317"/>
    <dbReference type="eggNOG" id="ENOG502QVQT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017490_2_1_1"/>
    <dbReference type="OMA" id="HWVVYAT"/>
    <dbReference type="OrthoDB" id="432169at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051285">
        <property type="entry name" value="NADH_oxidoreductase_modular"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
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        <property type="entry name" value="DIFLAVIN FLAVOPROTEIN A 2-RELATED"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR32145:SF31">
        <property type="entry name" value="FLAVIN REDUCTASE-LIKE FMN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00258">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="3">
        <location>
            <begin position="268"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="588" mass="62968" checksum="900FCDB69EDE3874" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTI4</accession>
    <name>A4RTI4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416308.1">
        <property type="nucleotide sequence ID" value="XM_001416271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTI4"/>
    <dbReference type="GeneID" id="5000273"/>
    <dbReference type="Gramene" id="ABO94601">
        <property type="protein sequence ID" value="ABO94601"/>
        <property type="gene ID" value="OSTLU_92266"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92266"/>
    <dbReference type="HOGENOM" id="CLU_062941_0_0_1"/>
    <dbReference type="OrthoDB" id="545589at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="26019" checksum="48DD9087C1E01AC6" modified="2007-05-15" version="1">MQRTTRKRRERREKNDEKRTNDCENGCDTCFYAAENGHLECLKYAREHGCDWDVWTCRGAAYYGHLECLKYAHENGCPWNWATCIAAAVNGHLECLKYARKNGCPWDEKTCEGAAKYGQLECLKYAHEHGCPWDELTCWSAAYYGHLECLKYACAHGFPGSDPYATALNEVCIPDADKRLGVEVALMFHRANGGDISMREFLPVWKEHGELYREAHLRVARELAPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTI5</accession>
    <name>A4RTI5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416309.1">
        <property type="nucleotide sequence ID" value="XM_001416272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTI5"/>
    <dbReference type="GeneID" id="5000281"/>
    <dbReference type="Gramene" id="ABO94602">
        <property type="protein sequence ID" value="ABO94602"/>
        <property type="gene ID" value="OSTLU_14095"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14095"/>
    <dbReference type="HOGENOM" id="CLU_1339463_0_0_1"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="205" mass="21518" checksum="D1D7CC2FDE0F77CA" modified="2007-05-15" version="1">MGRALRGLVRGAGDAGVADDASGTRGARRFTREQREREKMSGVTTTRVGATRWDDGEAESDGAARGTWFAGAAESLARVGSTATETNANAAPSASASEDVARDELFERRASSEARSAPTAAAGERARRVDAMRGADRLDASSDVLSECADVLAETQDVGASVLETLAAQRESLIRSGAAARGAKKKMDENLKIVKGMNSWTRLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTM8</accession>
    <name>A4RTM8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416288.1">
        <property type="nucleotide sequence ID" value="XM_001416251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTM8"/>
    <dbReference type="GeneID" id="5000204"/>
    <dbReference type="Gramene" id="ABO94581">
        <property type="protein sequence ID" value="ABO94581"/>
        <property type="gene ID" value="OSTLU_29819"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29819"/>
    <dbReference type="HOGENOM" id="CLU_2324536_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="99" mass="9966" checksum="CBDD79E5F5EFB483" modified="2007-05-15" version="1">MKKSYGTLAAAIGGDGRDESTPLLQNRRREAAWALTVSLVLAAVVGASMLTLAYVLTTNAKSVEDHVKAQLGGWTSFGKSAAATTTATAAAAAGRAGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTS2</accession>
    <name>A4RTS2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416834.1">
        <property type="nucleotide sequence ID" value="XM_001416797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTS2"/>
    <dbReference type="GeneID" id="5000590"/>
    <dbReference type="Gramene" id="ABO95127">
        <property type="protein sequence ID" value="ABO95127"/>
        <property type="gene ID" value="OSTLU_30364"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30364"/>
    <dbReference type="HOGENOM" id="CLU_667980_0_0_1"/>
    <dbReference type="OrthoDB" id="10474366at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="412" mass="44582" checksum="AF022F2356D1F933" modified="2007-05-15" version="1">MLRARRAETDDCGRTRQEDTRVDGGLAAYARAVEETMEAYDVRHAHVDARARIALRHSATLESTIRKQEESWVALERELAEVSGMTAKVWEQSESLNRTVELLSEVEEMLLEAEIGAELDALYKRRDDAEAKDAEAEAAFQEEVAHVLQLHDMLVNDAMTNQVSSRTTEEIAAEQELKKKLASLAKKKSKDVSVLSKDESLKDIASSLDVASTMSSKMTSDLDDFFNADADGDERDASSGKMYTLYGVRARADQTKGAILNQPHEIKSEKSMDVGEAERIALARKEALGIADEDMHGVNLRPPPPKGGAQDGPLEEAQSPRRIVIEAKSVSHQVSDTLKNFSMGGIWESASASTAAAAERASAATAAATAAATAAAAAGKDAVRALQERTTRKPAVEADAPTYYKKDAGTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTS3</accession>
    <name>A4RTS3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416546.1">
        <property type="nucleotide sequence ID" value="XM_001416509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTS3"/>
    <dbReference type="GeneID" id="5000790"/>
    <dbReference type="Gramene" id="ABO94839">
        <property type="protein sequence ID" value="ABO94839"/>
        <property type="gene ID" value="OSTLU_92362"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92362"/>
    <dbReference type="eggNOG" id="ENOG502S861">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_928548_0_0_1"/>
    <dbReference type="OMA" id="CEDECET"/>
    <dbReference type="OrthoDB" id="10264367at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050744">
        <property type="entry name" value="AI-2_Isomerase_LsrG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336:SF1">
        <property type="entry name" value="(4S)-4-HYDROXY-5-PHOSPHONOOXYPENTANE-2,3-DIONE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336">
        <property type="entry name" value="QUINOL MONOOXYGENASE YGIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="39"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="272" mass="30605" checksum="2F1A42340EECE003" modified="2007-05-15" version="1">MLTRRATIHPPRVAIRSRRATRARDGRRRRDARVRASARITLVRCDVKAEAMDDFLRLTEENARASVREAGNVRFDVLRDEKDRNLVTLVEIYADDASAAKHKETKHYETWRDEVADMMAAPRSAETYLAIEPNDDAWTYANAVTWNEDDDQSEMVNASCVHVHCECAAGDEAAFASACAKNASESALEDGNLRFDVFQSAESARKFLLVEVYDGAASAVAHKSTPHYEAWREEVANMMARPRQARAYDVVFPPTKISWRGDACGDACDTTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTV7</accession>
    <name>A4RTV7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_30400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416851.1">
        <property type="nucleotide sequence ID" value="XM_001416814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTV7"/>
    <dbReference type="STRING" id="436017.A4RTV7"/>
    <dbReference type="GeneID" id="5000842"/>
    <dbReference type="Gramene" id="ABO95144">
        <property type="protein sequence ID" value="ABO95144"/>
        <property type="gene ID" value="OSTLU_30400"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30400"/>
    <dbReference type="eggNOG" id="KOG0235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_9_5_1"/>
    <dbReference type="OMA" id="VWRHGNT"/>
    <dbReference type="OrthoDB" id="354304at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF44">
        <property type="entry name" value="PHOSPHATASE C1620.13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="23973" checksum="936996EAD909BF8A" modified="2007-05-15" version="1">MPSTRVVFFRHAQSEFNARHSIQGQLDPPLDETGLEQVALAAPRAAAAHDDAVAVFSSDLRRASVTGRAIADALDLALIEDANLRERHLGDLQGLERASLATSVPSAFKVWKSRDRNAAVPGGGESSAGVDARLSAFFQTVSTGNYAGKKIIAVTHGGVLGRLFAGGANREEKRLCQMRRGVGNFAECVVDAYDDGTWRCHYSGWASGRFLEDSEATLQADDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU27</accession>
    <name>A4RU27_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416887.1">
        <property type="nucleotide sequence ID" value="XM_001416850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU27"/>
    <dbReference type="GeneID" id="5001139"/>
    <dbReference type="Gramene" id="ABO95180">
        <property type="protein sequence ID" value="ABO95180"/>
        <property type="gene ID" value="OSTLU_92399"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92399"/>
    <dbReference type="HOGENOM" id="CLU_2067492_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="119" mass="13196" checksum="95B7792D59F5DE77" modified="2007-05-15" version="1" fragment="single">VLMCLGARAPGVRARGSPSVAATLTARSCLHLPPGPRRRISFPDRIRALLSLDRPMWRGSHELPRSTSSDARSTVACGDRADAALDFSRRERDVPLHRFARSSHDPPRGVWTPLRPLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU72</accession>
    <name>A4RU72_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MPT family transporter: inner membrane translocase (Import) Tim23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_7965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416908.1">
        <property type="nucleotide sequence ID" value="XM_001416871.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU72"/>
    <dbReference type="STRING" id="436017.A4RU72"/>
    <dbReference type="GeneID" id="5000913"/>
    <dbReference type="Gramene" id="ABO95201">
        <property type="protein sequence ID" value="ABO95201"/>
        <property type="gene ID" value="OSTLU_7965"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7965"/>
    <dbReference type="eggNOG" id="KOG3324">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118311_0_0_1"/>
    <dbReference type="OMA" id="DWKNTVA"/>
    <dbReference type="OrthoDB" id="159299at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045238">
        <property type="entry name" value="Tim23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371:SF0">
        <property type="entry name" value="SD19278P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371">
        <property type="entry name" value="TIM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="160" mass="16728" checksum="53F5C24BF4B9E8B4" modified="2007-05-15" version="1" fragment="single">PSMNKAIYALSDTPEFLFDEERTVKTRSWSENLTYLTGVGYLGGSIAGGGWGLYGSMKAAPEPALDTSKLRLNRMLNAVSQRGRSMGNTLGCLGLYYAALESASMAYLENRHDSLCSIFAGGGAGALYKSMSGPRAVAVYGAGGALLSGLNVAAQSIIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU75</accession>
    <name>A4RU75_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_34182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416910.1">
        <property type="nucleotide sequence ID" value="XM_001416873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU75"/>
    <dbReference type="STRING" id="436017.A4RU75"/>
    <dbReference type="GeneID" id="5000618"/>
    <dbReference type="Gramene" id="ABO95203">
        <property type="protein sequence ID" value="ABO95203"/>
        <property type="gene ID" value="OSTLU_34182"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34182"/>
    <dbReference type="eggNOG" id="KOG4315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2019087_0_0_1"/>
    <dbReference type="OMA" id="RENYEHK"/>
    <dbReference type="OrthoDB" id="5577072at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13153">
        <property type="entry name" value="KOW_GPKOW_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041994">
        <property type="entry name" value="GPKOW_KOW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045166">
        <property type="entry name" value="Spp2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818">
        <property type="entry name" value="G PATCH AND KOW-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818:SF2">
        <property type="entry name" value="G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25088">
        <property type="entry name" value="GPKOW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KOW" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="13593" checksum="63FAEFB7C7DC61EE" modified="2007-05-15" version="1">MSAKPWLFANIRVRVVSKSFKRGQFYLMKGVVVDVLTPTECMLQLEENGTTIEVSQSALETVVPKPGGRICVVSGKFRGRRGKLLEKNKSTDTASIQLSDDFEAHMLPLDAIAEYSGALDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU79</accession>
    <name>A4RU79_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Possible early light inducible protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ELIP3</name>
        <name evidence="1" type="ORF">OSTLU_33858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416624.1">
        <property type="nucleotide sequence ID" value="XM_001416587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU79"/>
    <dbReference type="STRING" id="436017.A4RU79"/>
    <dbReference type="GeneID" id="5000607"/>
    <dbReference type="Gramene" id="ABO94917">
        <property type="protein sequence ID" value="ABO94917"/>
        <property type="gene ID" value="OSTLU_33858"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33858"/>
    <dbReference type="eggNOG" id="ENOG502QTY8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094768_0_0_1"/>
    <dbReference type="OMA" id="CPAVYDE"/>
    <dbReference type="OrthoDB" id="566010at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="170" mass="19131" checksum="DBEE9FE6C88172A4" modified="2007-05-15" version="1">MTGAIFAGEQSQWKDPRWKNGNWDLDMFKNAAGEVDWDAVIDAEVVHRKMLEDNPAVYDEDGLFDTSIVPWQVWMRRFHLPEAEKANGRAAMVGYAFAYLIDAAGGAGLVDLHNSFLGKTAIFATILFVTLVRSLKDIDNLKDLAAEATFYDKQWNASWEGVDRPSESQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUB0</accession>
    <name>A4RUB0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_45194</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416640.1">
        <property type="nucleotide sequence ID" value="XM_001416603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUB0"/>
    <dbReference type="STRING" id="436017.A4RUB0"/>
    <dbReference type="GeneID" id="5001052"/>
    <dbReference type="Gramene" id="ABO94933">
        <property type="protein sequence ID" value="ABO94933"/>
        <property type="gene ID" value="OSTLU_45194"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45194"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_2_1"/>
    <dbReference type="OMA" id="KGLYWAR"/>
    <dbReference type="OrthoDB" id="10250117at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990221">
        <property type="term" value="C:L-cysteine desulfurase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000003">
        <property type="entry name" value="Cysteine desulfurase IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000002">
        <property type="entry name" value="Cysteine desulfurase IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010611">
        <property type="entry name" value="PRK14012.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="10">
        <location>
            <begin position="2"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="395" mass="43994" checksum="2F2A4899B4139CD1" modified="2007-05-15" version="1">MQATTPLDPRVLDAMLPYFTEQYGNPHSRTHMYGWETEDAIEKARGELASLIGANAKEIVFTSGATESNNMSLKGVARFYKDKKKHIITTTTEHKCVLDSCRQLEREGFDVTYLPVKENGLVDLKELEAAMRDDTAIVSVMAVNNEIGVIQPLKAIGELCRSKKIFFHTDGAQAVGKVPMDVNDMNIDLMSISGHKFYGPKGIGALYVRRRPRVRMEPIINGGGQERGLRSGTLPTPLIVGIGEAARVAQKELQRDEEHVNRLAKRLIEGIESRVEHTQLNGDREARYHGNVNMSFAYVEGESMLMGLKEIAVSSGSACTSASLEPSYVLRALGVNEEMAHTSVRYGLGRFTTEAEVDRAIEATVRQVEKLREMSPLWEMVQEGIDLKTIEWSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUH5</accession>
    <name>A4RUH5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acid phosphatase/vanadium-dependent haloperoxidase-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416961.1">
        <property type="nucleotide sequence ID" value="XM_001416924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUH5"/>
    <dbReference type="GeneID" id="5000777"/>
    <dbReference type="Gramene" id="ABO95254">
        <property type="protein sequence ID" value="ABO95254"/>
        <property type="gene ID" value="OSTLU_30621"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30621"/>
    <dbReference type="eggNOG" id="ENOG502S2DJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073969_1_1_1"/>
    <dbReference type="OMA" id="FMETGGM"/>
    <dbReference type="OrthoDB" id="1716650at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003832">
        <property type="entry name" value="DUF212"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446">
        <property type="entry name" value="ACID PHOSPHATASE/VANADIUM-DEPENDENT HALOPEROXIDASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446:SF29">
        <property type="entry name" value="ACID PHOSPHATASE_VANADIUM-DEPENDENT HALOPEROXIDASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02681">
        <property type="entry name" value="DUF212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17222" checksum="535E11443C3EB7A8" modified="2007-05-15" version="1">MASKISHIPAVVSSPALIAALLSFSIAQIAKVFTHYHATGKVDYSRIVGSGGMPSSHTALVVGLCTSIGLKEGMQSSIFALCLVFSLVVMYDATGVRLHAGRQAEVLNQLIVELPRDHPLTDSRPLRDTLGHTPIQVVVGAILGMSVAYAHFVYWMSTYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUH6</accession>
    <name>A4RUH6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_34214</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416672.1">
        <property type="nucleotide sequence ID" value="XM_001416635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUH6"/>
    <dbReference type="STRING" id="436017.A4RUH6"/>
    <dbReference type="GeneID" id="5001103"/>
    <dbReference type="Gramene" id="ABO94965">
        <property type="protein sequence ID" value="ABO94965"/>
        <property type="gene ID" value="OSTLU_34214"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34214"/>
    <dbReference type="eggNOG" id="KOG0548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_44_4_1"/>
    <dbReference type="OrthoDB" id="539868at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="131" mass="14166" checksum="1267E480E43597E6" modified="2007-05-15" version="1" fragment="single">MARSSAEAREIDAGALRHAVEAAKRRGNEAFARRAYGEAMEAYTVAIAGREDDKTLYSNRSAAALGMGLVEEALRDAAACVRADETWAKGYYRLGCALMSAFESGKAVAAFRRGLELAPESVDMKERLEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUK9</accession>
    <name>A4RUK9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416977.1">
        <property type="nucleotide sequence ID" value="XM_001416940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUK9"/>
    <dbReference type="GeneID" id="5000615"/>
    <dbReference type="Gramene" id="ABO95270">
        <property type="protein sequence ID" value="ABO95270"/>
        <property type="gene ID" value="OSTLU_14657"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14657"/>
    <dbReference type="HOGENOM" id="CLU_2175246_0_0_1"/>
    <dbReference type="OrthoDB" id="7688at13792"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="110" mass="11679" checksum="D43B0C93F98ECFF4" modified="2007-05-15" version="1">MAREATAATAATEAERAFRAKYGDDLRPKPRLIATDVKHFDSADWAMRKSAEEARRRDAGGTAATRSEGRAMGEGTTEDSAREPDERGAREGDATSTREGDGCASEGADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUV7</accession>
    <name>A4RUV7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">MC family transporter: aspartate/glutamate (Ca2+-activated)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_34060</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416737.1">
        <property type="nucleotide sequence ID" value="XM_001416700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUV7"/>
    <dbReference type="STRING" id="436017.A4RUV7"/>
    <dbReference type="GeneID" id="5000732"/>
    <dbReference type="Gramene" id="ABO95030">
        <property type="protein sequence ID" value="ABO95030"/>
        <property type="gene ID" value="OSTLU_34060"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34060"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_10_2_1"/>
    <dbReference type="OMA" id="YKMSVPK"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="30"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="129"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="236"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="35820" checksum="B1F5E7BEA7DC0AA5" modified="2007-05-15" version="1">MTTPTATTTTAATRASASARSSDAPSLTFAAIARSLIAGGVAGGVSRTAVAPLERLKILQQVSSSSAYNGVYSGLSHMWKTEGVKGLFKGNGANCVRIVPNSAVKFFCYEHMAHGLLDLRRTFDKDAEMDVLTRLGGGAGAGIVAMSATYPLDMIRGRLTVQKSAADAAKSGGANYRGIYHAFTVIAQKEGFGAFYKGWTPSVIGVIPYVGLNFAIYETLKDQTVKMQGLRSASDLSVFAGLVCGGVAGAVGQTVAYPFDVCRRRLQVSGWVQAGVQAGGPVYTGMFDCFRRTVAEEGVSALFHGLSANYIKIMPSIAIAFVVYDQLKIILKPEIKISAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV43</accession>
    <name>A4RV43_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_34104</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="2"/>
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        <property type="protein sequence ID" value="ABO95071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416778.1">
        <property type="nucleotide sequence ID" value="XM_001416741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV43"/>
    <dbReference type="STRING" id="436017.A4RV43"/>
    <dbReference type="GeneID" id="5000899"/>
    <dbReference type="Gramene" id="ABO95071">
        <property type="protein sequence ID" value="ABO95071"/>
        <property type="gene ID" value="OSTLU_34104"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34104"/>
    <dbReference type="eggNOG" id="KOG2007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013528_3_1_1"/>
    <dbReference type="OMA" id="FHNDMKS"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="12">
        <location>
            <begin position="58"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="638"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="746" mass="83086" checksum="B2AD515E8F783FA1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV47</accession>
    <name>A4RV47_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417075.1">
        <property type="nucleotide sequence ID" value="XM_001417038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV47"/>
    <dbReference type="GeneID" id="5000746"/>
    <dbReference type="Gramene" id="ABO95368">
        <property type="protein sequence ID" value="ABO95368"/>
        <property type="gene ID" value="OSTLU_30845"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30845"/>
    <dbReference type="HOGENOM" id="CLU_790826_0_0_1"/>
    <dbReference type="OMA" id="TTNWFES"/>
    <dbReference type="OrthoDB" id="498784at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="37851" checksum="36B7CF4F5B8B7F22" modified="2007-05-15" version="1">MAIQQALQPKDTEYEYEYEYAAESIEGAPNRRRRRLLSASEARARKLPEGAEVITQVQHPVDLRAAAKRALQRRNGTSTESIERRHLSEIVDVTYDDVELFTTNWFESFPATLPLAIRDRFIALLEEYVVDPQIRISLDITVALVGVATPGVGITTYEAAAENTISNQIVFHGYDAAIDFASAIDPAVAIAGSISKGIAVANAIDDATKIIDAVTSIVNEVNSIVESDIASREADANGEVSAQGGGDDANMTLTERVKRWIRPLSNDTAVEGPRGVDTARATHFTSLGKNTSTNGAADYDEYEDAGGEARASDYVDYDYEPLGAVSGTYAVAVSLIFLEQIALNGGSITVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVJ6</accession>
    <name>A4RVJ6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_49379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417151.1">
        <property type="nucleotide sequence ID" value="XM_001417114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVJ6"/>
    <dbReference type="STRING" id="436017.A4RVJ6"/>
    <dbReference type="GeneID" id="5001153"/>
    <dbReference type="Gramene" id="ABO95444">
        <property type="protein sequence ID" value="ABO95444"/>
        <property type="gene ID" value="OSTLU_49379"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49379"/>
    <dbReference type="eggNOG" id="KOG1299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013933_3_1_1"/>
    <dbReference type="OMA" id="VHQLNNA"/>
    <dbReference type="OrthoDB" id="10266265at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009705">
        <property type="term" value="C:plant-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009846">
        <property type="term" value="P:pollen germination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000012">
        <property type="term" value="P:regulation of auxin polar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000067">
        <property type="term" value="P:regulation of root morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031338">
        <property type="term" value="P:regulation of vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="565" mass="62676" checksum="2691935CDDE68794" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVX4</accession>
    <name>A4RVX4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417486.1">
        <property type="nucleotide sequence ID" value="XM_001417449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVX4"/>
    <dbReference type="STRING" id="436017.A4RVX4"/>
    <dbReference type="GeneID" id="5001500"/>
    <dbReference type="Gramene" id="ABO95779">
        <property type="protein sequence ID" value="ABO95779"/>
        <property type="gene ID" value="OSTLU_31132"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31132"/>
    <dbReference type="HOGENOM" id="CLU_539062_0_0_1"/>
    <dbReference type="OMA" id="NFELIWP"/>
    <dbReference type="OrthoDB" id="10483202at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="249"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="506" mass="56205" checksum="BF97880CE6594B37" modified="2007-05-15" version="1">MLARERGENARLSEENARLGEELRARGTETPATRDEEEEEEEALDETVKELFDLVESERRARRALEEKLSEYERGAGEERDEDATRRAEEAEETVREQEKKLSQAADIIGELRTTLLQVMETENRGGAPESVTTNSQVDGEERRDGGTPLERTTAAVKVWEGKVEKLVLETVKSALERAMDSPALQTNKREGEQVVSSVTDAINHELSAIVENAMSGIVDEMRFQFGQEDEDEEEMGSVGGRKRFIVWLADENMRRAQLEEQLTNVQDELARSEASRQIATQRWLQAMNQIDGSAFDDESDLGEILSRVDDMSDDGTSVYSLEPGDLGSPRRRRPAANRRAMSVVGEAPMRSDARRRATKSETHEHVNLHDVSIGPHGRLETFKEEEDDPIVDLAIEATPGGSVYFALRAAARNVLVPCVTRAAVVIYRIAQHIHALCVYCASSPNFELIWPVVLLLAAFYWKIGAFDGAVVASPAVAVVAERTARARVAAPPAVAHHPPSIRIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RW81</accession>
    <name>A4RW81_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_31245</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417536.1">
        <property type="nucleotide sequence ID" value="XM_001417499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RW81"/>
    <dbReference type="STRING" id="436017.A4RW81"/>
    <dbReference type="GeneID" id="5001225"/>
    <dbReference type="Gramene" id="ABO95829">
        <property type="protein sequence ID" value="ABO95829"/>
        <property type="gene ID" value="OSTLU_31245"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31245"/>
    <dbReference type="eggNOG" id="KOG0776">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_1_2_1"/>
    <dbReference type="OMA" id="AFDYYLH"/>
    <dbReference type="OrthoDB" id="9927103at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF69">
        <property type="entry name" value="ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="332" mass="36344" checksum="7E9B0DCBE144F09C" modified="2007-05-15" version="1">MRRAVTSDIPALSTASEYFFKLGAEGKRVRPTVLMLMASAMTNGVMTSAAQGGWRETDHAPAHQAPADVRRRQQRLAEIAEMIHVASLLHDDVLDNAATRRGLRALNLEVGNKLAILAGDFLLARASVTLASLRNTEVIELLSRVLEHLVAGEVMQMTAKPESLSSMDHYVKKTYYKTASLIANSSKAIALLGGHGEESAQLAYDYGKNLGLAFQFQDDVLDFIGSESLLGKPTLGDLKEGIATAPVLFAVQEFPELSDLVERRFKHSGDVQRAHELVKSSQGIARTQELAREHCDLAIAAIDRLPASESKYAMHCRRALKELAKRAVERSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWA8</accession>
    <name>A4RWA8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_37252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417548.1">
        <property type="nucleotide sequence ID" value="XM_001417511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWA8"/>
    <dbReference type="STRING" id="436017.A4RWA8"/>
    <dbReference type="GeneID" id="5001346"/>
    <dbReference type="Gramene" id="ABO95841">
        <property type="protein sequence ID" value="ABO95841"/>
        <property type="gene ID" value="OSTLU_37252"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37252"/>
    <dbReference type="eggNOG" id="KOG2076">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002391_1_1_1"/>
    <dbReference type="OMA" id="FEDLHEH"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039340">
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    </dbReference>
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            <begin position="66"/>
            <end position="99"/>
        </location>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="689" mass="77659" checksum="372AB3718DF587AB" modified="2007-05-15" version="1"> </sequence>
</entry>
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    <accession>A4RX76</accession>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="17460045"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="gene ID" value="OSTLU_92723"/>
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    <dbReference type="OrthoDB" id="497551at2759"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0003676">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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    </protein>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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            <end position="67"/>
        </location>
    </feature>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO96016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="329" mass="36934" checksum="8BFB56C46BAD81DE" modified="2007-05-15" version="1">MEIALDGGWTREAYARAKREELARLETRGERRERAGRGDASVAPRRSSSSAPTLDDEGVRGTPDADLDERRLTLSSVQCGQRVVPESVFKTPKPSRFGPAHATVAASASPIGASEARANANALDAAIVRVKSQLLFCEKATRKRRKTLEEYTWTDHEVLQVLLKRVKYDVASARQLMMISRSFLESRDRIHADVTYAQTLRTAIDTLERDVRLIIAGKDETREHDGDHRSLHLLWPDEQSETNTEAHALLSSALRARSSWADDQAREIGAEHSKRLREITRAQNDLLATITEGSCDQMTHDAACKAIYMVLRMYKTIFLLTEHARARTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXE3</accession>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001417698.1"/>
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    <dbReference type="GeneID" id="5001918"/>
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        <property type="gene ID" value="OSTLU_31664"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31664"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
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    </dbReference>
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    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
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            <end position="824"/>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="654"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="757"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="878" mass="95889" checksum="5AA39123AAE3BDBC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY63</accession>
    <name>A4RY63_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DMT family transporter: UDP-galactose/UDP-glucose</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_45749</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417875.1">
        <property type="nucleotide sequence ID" value="XM_001417838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY63"/>
    <dbReference type="GeneID" id="5001926"/>
    <dbReference type="Gramene" id="ABO96168">
        <property type="protein sequence ID" value="ABO96168"/>
        <property type="gene ID" value="OSTLU_45749"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45749"/>
    <dbReference type="eggNOG" id="KOG1582">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036019_2_0_1"/>
    <dbReference type="OMA" id="QIMFKSA"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF8">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="400" mass="42536" checksum="B3F6744F22955647" modified="2007-05-15" version="1">MISRATTVAIAPNARAQTHARQRRAPSVRASTSAPTLGGRRSAIVGGGAVALEQRAMATRAERRRVVTRAGGVAKAAPGEPKKVFGLTLPEGEGISFAILAAGSLGSALGFAALQEGVFRIPGFKFSAWMTVLTTFTYFLCGALEMKLTKDSRKGSWKNYGILSVYTYGGMALTNYALSYLNYATRIVFKSAKIIPVMAFSVLIVGKKYNWKEWLSAAILVAGIVLFTLGDVASSPAFAPIGVALIAAALCVDAICANFEEKNFFRCETPSTTQEVLCYASLIGTAYGLVPLIASGGLAPALAFSQANPQVVPMIMAFSVMGYSSVSFILSLIKYFGATEAEIVKSLRKVLSIVISFALFPKELNWKYIAGFAAVVVSTVYTFYLKQQKNAAKAAAKAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY87</accession>
    <name>A4RY87_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417886.1">
        <property type="nucleotide sequence ID" value="XM_001417849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY87"/>
    <dbReference type="STRING" id="436017.A4RY87"/>
    <dbReference type="GeneID" id="5002016"/>
    <dbReference type="Gramene" id="ABO96179">
        <property type="protein sequence ID" value="ABO96179"/>
        <property type="gene ID" value="OSTLU_15613"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15613"/>
    <dbReference type="HOGENOM" id="CLU_468852_0_0_1"/>
    <dbReference type="OrthoDB" id="10518289at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="25"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="582" mass="62412" checksum="F5514B5F27F3B8E4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYB4</accession>
    <name>A4RYB4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SOUL heme-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_40872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418356.1">
        <property type="nucleotide sequence ID" value="XM_001418319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYB4"/>
    <dbReference type="STRING" id="436017.A4RYB4"/>
    <dbReference type="GeneID" id="5002568"/>
    <dbReference type="Gramene" id="ABO96649">
        <property type="protein sequence ID" value="ABO96649"/>
        <property type="gene ID" value="OSTLU_40872"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40872"/>
    <dbReference type="eggNOG" id="ENOG502QWGB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053942_1_0_1"/>
    <dbReference type="OMA" id="QGIDRTM"/>
    <dbReference type="OrthoDB" id="44820at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF50">
        <property type="entry name" value="SOUL HEME-BINDING FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="40526" checksum="03330AEACDE6995C" modified="2007-05-15" version="1">MTRRTTRPTTRDARRRTTTATRATTTTSSTAKGMDEEESARMRKALAEDLTHLFDDEGIDPSLYAKDVSFEDPLTKYDSFDGYAFNIQMLRRVFSPTYAMHEIYQSGPWEITTRWTMVMGLPTFPFAWRPTLTFTGTSIMGIDEETKKVTRHVDTWDSIENQRHLSAEGVVEVLKQIFDFAQTPDLDTPGYVVLKKRRDYEVRRYEPYLVAATGPGLNVKEVSSSSAKMNGQVAGQAFNSLAGYIFGQANASGTKMEMTTPVFTKNATMQFVVSGDSVDALPASTNENVVLREESGGIFVAKKFSGVATEEAARDVEKQLRKLIENDGLEASGAAALAQYNDPFTNPFLRRNEIIIPVSNFTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYS5</accession>
    <name>A4RYS5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_41230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418443.1">
        <property type="nucleotide sequence ID" value="XM_001418406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYS5"/>
    <dbReference type="STRING" id="436017.A4RYS5"/>
    <dbReference type="CAZy" id="GT77">
        <property type="family name" value="Glycosyltransferase Family 77"/>
    </dbReference>
    <dbReference type="GeneID" id="5002323"/>
    <dbReference type="Gramene" id="ABO96736">
        <property type="protein sequence ID" value="ABO96736"/>
        <property type="gene ID" value="OSTLU_41230"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41230"/>
    <dbReference type="eggNOG" id="ENOG502QRD4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064181_0_0_1"/>
    <dbReference type="OMA" id="ACESTER"/>
    <dbReference type="OrthoDB" id="540503at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080147">
        <property type="term" value="P:root hair cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044290">
        <property type="entry name" value="RRA1/2/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46581">
        <property type="entry name" value="ARABINOSYLTRANSFERASE RRA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46581:SF3">
        <property type="entry name" value="ARABINOSYLTRANSFERASE RRA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="1">
        <location>
            <begin position="100"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="37071" checksum="31A54F8ED282FC83" modified="2007-05-15" version="1" fragment="single">MEPFALRAINGRRTDAFVVDDSRPNRCEPKRINRRIWGSARSLDFIVPRDSEEWPQNCDGREALCEVLRRVAKNREVLAAVANSQAPGLTPFLEMLIALKVPNFLVIALDEPLTKRLDELGVPYYFHEDPVMGNHKVSAKKFALIQEFVAVGCSVLLTDTDVTYQQNPFDYLYRDSDIESMSDGFDNDSANGFLQPIDDVSFGEARRRAGSFRVAALNSGMWYVSATEASLRLMKIMAHRLATEELWDQSGYNLELWFASRDAHMTSGATVRVMDPFCFMNSKVMFRIIRHSKPLQRENHRPVAMHANYHTDKDNKIKLVHAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYU4</accession>
    <name>A4RYU4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">General transcription factor IIH subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_41034</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the GTF2H2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418454.1">
        <property type="nucleotide sequence ID" value="XM_001418417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYU4"/>
    <dbReference type="STRING" id="436017.A4RYU4"/>
    <dbReference type="GeneID" id="5002331"/>
    <dbReference type="Gramene" id="ABO96747">
        <property type="protein sequence ID" value="ABO96747"/>
        <property type="gene ID" value="OSTLU_41034"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41034"/>
    <dbReference type="eggNOG" id="KOG2807">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028556_1_2_1"/>
    <dbReference type="OMA" id="INWVEVP"/>
    <dbReference type="OrthoDB" id="284275at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000015">
        <property type="entry name" value="General transcription factor IIH subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007198">
        <property type="entry name" value="Ssl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04056">
        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015919">
        <property type="entry name" value="TFIIH_SSL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="12">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR015919-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO96747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="407" mass="44327" checksum="107E7DB5EAEFF373" modified="2007-05-15" version="1">MTSVEAAYGAEGANGDDDDDDVDAEDAQRALRAWEKKYQSERAWEDLEEDPVTGRLRVTSEAQTAKARERRAKMAALATSAGAAKGMIRFTYVVVDLSRAANEEDFRPNRLSVVGQCATSFIREYFNQNPLSQLGIIVARNGVAERLTELSGSPEAHAAALRNALDASGDFSLQNTLNVARTSLKSIPSYGSREVLYIVSSLSTCDPGNVWTEIAATKAAKVRVSVVAVAAELHVSRRLTEETGGTYGVSLNADHLDDLIMAHAPPPPLPEDATKSSLVQMGFPQKKHLSKDALVVGTGGEYVCPRCSGRIDELPSQCAVCRLTLVSSPHLARSYHHLFPVAPFKEYTRDEASAKEVLECKACLALIKQTDPASKCEQCSNVFCFACDCYIHEKLHNCPHCTCEREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ47</accession>
    <name>A4RZ47_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_41375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418267.1">
        <property type="nucleotide sequence ID" value="XM_001418230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ47"/>
    <dbReference type="STRING" id="436017.A4RZ47"/>
    <dbReference type="GeneID" id="5002476"/>
    <dbReference type="Gramene" id="ABO96560">
        <property type="protein sequence ID" value="ABO96560"/>
        <property type="gene ID" value="OSTLU_41375"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41375"/>
    <dbReference type="eggNOG" id="ENOG502S80R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065010_2_1_1"/>
    <dbReference type="OMA" id="YMPYMHS"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="178" mass="20038" checksum="BF7B1055CAFAD6BF" modified="2007-05-15" version="1">MALWFGSREEDDIVIHRTFGAHLRATSELYASQPADETIALESFEDVLADIITLDQFSRVIHRKTAKAFSNDAAAASLARRALSDDAFMKQAAPLERMFIEMPLMHSEDVADHESLLAMRGIDVSGIDVDGAHDDFAVKHYCVVRKFGRYPYRNKVLGRVNTPEEQVYLDSRPSTYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZQ1</accession>
    <name>A4RZQ1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">phytol kinase</fullName>
            <ecNumber evidence="12">2.7.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_35668</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>phytol + CTP = phytyl phosphate + CDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38055"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17327"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:75483"/>
            <dbReference type="EC" id="2.7.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; tocopherol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.182" evidence="12"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418836.1">
        <property type="nucleotide sequence ID" value="XM_001418799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZQ1"/>
    <dbReference type="STRING" id="436017.A4RZQ1"/>
    <dbReference type="GeneID" id="5003021"/>
    <dbReference type="Gramene" id="ABO97129">
        <property type="protein sequence ID" value="ABO97129"/>
        <property type="gene ID" value="OSTLU_35668"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35668"/>
    <dbReference type="eggNOG" id="KOG4453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058561_5_0_1"/>
    <dbReference type="OMA" id="SWPIFST"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010276">
        <property type="term" value="F:phytol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039606">
        <property type="entry name" value="Phytol/farnesol_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523:SF8">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523">
        <property type="entry name" value="PHYTOL KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="251" mass="26107" checksum="2EE923167EC207F2" modified="2007-05-15" version="1">MVFDAVAQFVASVDETPRDVAASALTTIGAFVWVKAFDALADRGAFASTTSRKLVHVTSGTFFACTWPLFSASGAARFFAAAIPLAQGVRLFGIGSGMIKNASAVRAVSREGGKEELLKGPLYYTAVLAACTSAYWRTNPIGIVAMAMMCGGDGFADLVGRKFGKGNALPWNEEKSFAGSAGFVAGGFGVASGLLAYFDAFGFIEATPTTYFVTLIIAFACALVESLPITSIVDDNFSVAITAIACGSLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4S050</accession>
    <name>A4S050_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_16121</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418682.1">
        <property type="nucleotide sequence ID" value="XM_001418645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S050"/>
    <dbReference type="STRING" id="436017.A4S050"/>
    <dbReference type="GeneID" id="5002964"/>
    <dbReference type="Gramene" id="ABO96975">
        <property type="protein sequence ID" value="ABO96975"/>
        <property type="gene ID" value="OSTLU_16121"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16121"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_559470_0_0_1"/>
    <dbReference type="OMA" id="AKMIFGC"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05476">
        <property type="entry name" value="pepsin_A_like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034161">
        <property type="entry name" value="Pepsin-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032799">
        <property type="entry name" value="TAXi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032861">
        <property type="entry name" value="TAXi_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683">
        <property type="entry name" value="ASPARTYL PROTEASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683:SF375">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14541">
        <property type="entry name" value="TAXi_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14543">
        <property type="entry name" value="TAXi_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="408"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="13">
        <location>
            <begin position="39"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="464" mass="50612" checksum="4183FB85FDB4ABB9" modified="2007-05-15" version="1">MRRRTTTATAGRRLSRADAIEIRSYGARLGNGYGSGHEFSLTVTLPGAQSFDLIVDTGSPLTYFPCVGCDAELCGYHEHQYYDWRLSNDFRLLNASMNAADAAFCDAMPVAHNVSADGECLFGLGYLDGARGGGSMIEDVVSVGDELSPAKMIFGCGGVVEADGGFDRQDGMAGFSRGNTAFHTQLAKAGVINAHVFGFCSEGSGTDTAMLSLGRYDFGRDLAPLSYTRILGADDLAVRTMSWKLGEAIIASSSNVYTVLDSGTTLVLLPPAMRDDFITKLVAQMAATHPELELFDDEDLGQMCFSSATPVLTAKLRDEWFPKLAITYDPDITLILPSENYLNSHLYIPHTYCLGIDESDDGTILLGQQALRNTFIEYDLENDRVGVVVAQCENLRKKFAPDTPHNPWRFVATIFILLFTACVVSAVSFCLYAKFGGQKPFKYRVFQVSDILDEEIEMGNVVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0B3</accession>
    <name>A4S0B3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418717.1">
        <property type="nucleotide sequence ID" value="XM_001418680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0B3"/>
    <dbReference type="STRING" id="436017.A4S0B3"/>
    <dbReference type="GeneID" id="5003034"/>
    <dbReference type="Gramene" id="ABO97010">
        <property type="protein sequence ID" value="ABO97010"/>
        <property type="gene ID" value="OSTLU_93035"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93035"/>
    <dbReference type="HOGENOM" id="CLU_404616_0_0_1"/>
    <dbReference type="OrthoDB" id="10421778at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="180"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="680" mass="74595" checksum="6AE7A3618107D35E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0D8</accession>
    <name>A4S0D8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418727.1">
        <property type="nucleotide sequence ID" value="XM_001418690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0D8"/>
    <dbReference type="STRING" id="436017.A4S0D8"/>
    <dbReference type="GeneID" id="5002936"/>
    <dbReference type="Gramene" id="ABO97020">
        <property type="protein sequence ID" value="ABO97020"/>
        <property type="gene ID" value="OSTLU_24827"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24827"/>
    <dbReference type="HOGENOM" id="CLU_539063_0_0_1"/>
    <dbReference type="OMA" id="VIKGFYM"/>
    <dbReference type="OrthoDB" id="10444206at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047259">
        <property type="entry name" value="QUIRKY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31425:SF50">
        <property type="entry name" value="FT-INTERACTING PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31425">
        <property type="entry name" value="PHOSPHORIBOSYLANTHRANILATE TRANSFERASE ISOFORM 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="455"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="506" mass="55431" checksum="7854419AE9A7B57B" modified="2007-05-15" version="1">MADDMKFSFGEASFNAEAPCTGAIRVDIVTTETGNLLGTTELDVMKLPRRKTDRHGNVAAAPSGRYHKLYSGDEGDDEDVGFVFLQAYVDPAVTYSQSQKPVLGELSIKVLKLNGLPESCAPALIANVGDAWALLPGFGGGGPSGWKRELHAAVRDAADQCTIGIYNRNKSDEMLGKIKFSPFSLPEHGRALVCTVPLTTRDVFGSGDDNGEATVRLQFKQKVSNTALFFHYCTPMLPMSAYRYGDMDEIMRDLDIINYEHLVTGRDALPEPLVRSILDVSDTDPSIATTRRTKASAMRLAATLESFGDVLKPLTQAVTWEKPMYTAALHISIFMCLWLPRLTFVGYFAFIAWYISLRNKPRVFTALGEDKSKLAGSVNVSKAPPGSTLSPLSSLVRESYGVAARATPSNDAYDAVVQISFWCQAQVEFLRAPLEKFNAILTWEDESESAKYQTLFLGAAVGFLFIPFRFVAAAILFVCLRHPWAAKPPLPPYKVALARRSIAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0F8</accession>
    <name>A4S0F8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plastid-encoded RNA polymerase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_35770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418965.1">
        <property type="nucleotide sequence ID" value="XM_001418928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0F8"/>
    <dbReference type="STRING" id="436017.A4S0F8"/>
    <dbReference type="GeneID" id="5002906"/>
    <dbReference type="Gramene" id="ABO97258">
        <property type="protein sequence ID" value="ABO97258"/>
        <property type="gene ID" value="OSTLU_35770"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35770"/>
    <dbReference type="eggNOG" id="KOG1521">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038421_0_1_1"/>
    <dbReference type="OMA" id="KKKCRAF"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07032">
        <property type="entry name" value="RNAP_I_II_AC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033901">
        <property type="entry name" value="RNAPI/III_AC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="5">
        <location>
            <begin position="60"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="360" mass="40050" checksum="DF5CF70AD386582B" modified="2007-05-15" version="1">MLERLEEQRHYVRAGAEHNANVNEVAYGGAYASVGKDFAFSAERFRETFALTLTTSDEERCVFELEGCSPAFANAFRRIILSEVPTMAIEKVFVVNNTSVVADEVFAHRLGLVPIKADPAMFEYRGEGDAANETNTIVLKMHVRCHKERNPDGTLGEVVNRSVYSNALTWCPEGSQLPEENGAKYSDFKRSQKEVVGDQELGCVHDDILLVKLAPGQEVELECHCVKGIGQEHAKWSPVGTCWYKMVPEITILEPITGADADEFMKKCANFSETHKCYACEGKGDKKTVKVVESRGCDFCVERVRELTGEPGWADKIAVRKRKDHFIFTIETIGQMAPGTIFKEAVKILASKAQNVLSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0V5</accession>
    <name>A4S0V5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_42574</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419042.1">
        <property type="nucleotide sequence ID" value="XM_001419005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0V5"/>
    <dbReference type="STRING" id="436017.A4S0V5"/>
    <dbReference type="GeneID" id="5003330"/>
    <dbReference type="Gramene" id="ABO97335">
        <property type="protein sequence ID" value="ABO97335"/>
        <property type="gene ID" value="OSTLU_42574"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42574"/>
    <dbReference type="eggNOG" id="KOG4720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_607430_0_0_1"/>
    <dbReference type="OMA" id="EAPYYKI"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="421" mass="46710" checksum="5F30546C91FDE5E2" modified="2007-05-15" version="1">MVTDRRHSSASEENSGASTTDFQDEDAPTSRSATPAPGRLNVELDVDREQRDEYQGVKSIVRNTVRGWANVENAALEVSPVRGGITNALFKVRLAQDAAPTTTKDPIARAVVVRVFGKGTDQFITHRKVQGETSHVLNEHGFGAKVLGVFSNGLVEEFIEAESVAPEELANGGILLRRVAAQMRRLHKETIARARANAIWDTLQLWFDLAYGVANDPTIFKNDARKESILASLKIDSESRQMLFEVIRARCEAVNSQTVYCHNDIHAGNFLLNRKTDNLTLIDYEYADYGPRAFDMANLFCEFAGFECNYDQFPTCELRREFYSAYLHTTVDAEIDALEAEVAAWTPVTHAFWALWAVIQAKYSAIDFDFLGFAAMRMKVFYASALAPSEWVPTNAALGGQHGTPEKSVGWNATAEGNVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0X2</accession>
    <name>A4S0X2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-carotene isomerase D27-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_7025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419261.1">
        <property type="nucleotide sequence ID" value="XM_001419224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0X2"/>
    <dbReference type="STRING" id="436017.A4S0X2"/>
    <dbReference type="GeneID" id="5003236"/>
    <dbReference type="Gramene" id="ABO97554">
        <property type="protein sequence ID" value="ABO97554"/>
        <property type="gene ID" value="OSTLU_7025"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7025"/>
    <dbReference type="eggNOG" id="ENOG502QTYT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076741_1_1_1"/>
    <dbReference type="OMA" id="CLAYICS"/>
    <dbReference type="OrthoDB" id="416096at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038938">
        <property type="entry name" value="D27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025114">
        <property type="entry name" value="D27-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33591">
        <property type="entry name" value="BETA-CAROTENE ISOMERASE D27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33591:SF4">
        <property type="entry name" value="OS08G0114100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13225">
        <property type="entry name" value="D27-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-carotene isomerase D27-like C-terminal" evidence="1">
        <location>
            <begin position="101"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="187" mass="20282" checksum="200B1501D01841CE" modified="2007-05-15" version="1" fragment="single">TTYADGALDALAISLFNAKLAAVVGEEASASANEKRGFERLVALADALADGRTVVEQRAAVTRALLSIIPAPVRFLFKKMIKPAPWVDEMNAYITREAFAWLVGPCEVMPRESDGVMAQVKLRKCRYLEQSGCSASCANFCKIPTQRFFKEAFGVDARLDPNHEDGSCVMTFGVKPDINDAAFAAPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0X9</accession>
    <name>A4S0X9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419265.1">
        <property type="nucleotide sequence ID" value="XM_001419228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0X9"/>
    <dbReference type="GeneID" id="5003437"/>
    <dbReference type="Gramene" id="ABO97558">
        <property type="protein sequence ID" value="ABO97558"/>
        <property type="gene ID" value="OSTLU_32904"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32904"/>
    <dbReference type="HOGENOM" id="CLU_2201432_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="108" mass="11677" checksum="FB8C9CFB273A7385" modified="2007-05-15" version="1">MSRDCATSPIYICVSNSSSSLRHPILLCFVRARLITSRIPHARSHAKSHTESPAPTAASSCNKDIVTKTGKSSLPDDSAFVYFLRSAAQFIATMCSKRGPNAVLCQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Z3</accession>
    <name>A4S0Z3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 56</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_50302</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419274.1">
        <property type="nucleotide sequence ID" value="XM_001419237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Z3"/>
    <dbReference type="STRING" id="436017.A4S0Z3"/>
    <dbReference type="GeneID" id="5003300"/>
    <dbReference type="Gramene" id="ABO97567">
        <property type="protein sequence ID" value="ABO97567"/>
        <property type="gene ID" value="OSTLU_50302"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50302"/>
    <dbReference type="eggNOG" id="KOG2573">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015495_4_1_1"/>
    <dbReference type="OMA" id="PDNYMFA"/>
    <dbReference type="OrthoDB" id="6780543at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000001">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000002">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="7">
        <location>
            <begin position="295"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="432"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="471" mass="51904" checksum="D9FAE9D6ADE3F0D6" modified="2007-05-15" version="1">MAQFVLFESSSGYGLFETLDLDVVGQALEKVQETTQSADKFGKVVKLHGFKPFTSAANALEQINCVSEGVASEDLQNFLEQNLPKLKDSKKAKFQLGVADSKLGNSIVETTKIPCVCNDHVGEIIRGIRAYFTKFVKGFKGGDYEKAQLGLAHSYSRAKVKFNVNRSDNMIIQAIALIDTLDKDINTFIMRVREWYGWHFPELVKVVNDNYMYARLALVIKDKATLTDEAMPALKEITGDEDKAKEVIEAAKASMGQDISPVDMINIESFAKRVISLAEYRTSLHNYLNNKMSVVAPNLGALIGDIIAARLISHAGSLTNLAKYPASTVQILGAEKALFRALKTKGNTPKYGLIFHSTFIGKANARNKGRISRYLANKCSIASRIDCFSDFQTTLFGEKLKDQVEERLAFYDKGTAPRKNIAMMQEVIAEIGPQAGGGGKRKATDSATATPKKSKKEKKDKKEKSAKKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="106" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1G0</accession>
    <name>A4S1G0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_33086</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419142.1">
        <property type="nucleotide sequence ID" value="XM_001419105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1G0"/>
    <dbReference type="STRING" id="436017.A4S1G0"/>
    <dbReference type="GeneID" id="5003465"/>
    <dbReference type="Gramene" id="ABO97435">
        <property type="protein sequence ID" value="ABO97435"/>
        <property type="gene ID" value="OSTLU_33086"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33086"/>
    <dbReference type="eggNOG" id="KOG0975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031922_0_1_1"/>
    <dbReference type="OMA" id="WLGLTQC"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009082">
        <property type="term" value="P:branched-chain amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF44">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO97435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="362" mass="40505" checksum="3548EAE5FDAE558D" modified="2007-05-15" version="1">MTGRPLPRCADEELGFGTVITDHMLKIEWNVERGWNHPMILPSGPVGLHPFAHVFHYAVECYEGMKAYVDNNGSVRLFRPEMNMQRFRVSAKRMSLPDFDGEQLLKCIETLVDIDKDWIPKQRGYSMYLRPVIFSTTPWLGLTQCAEAMILVLCCPVGPYFKSGFVPIKLSVDSKYIRAWPGGTGNVKSGGNYGPTVISQAAATANGASQSLFVYDKHEYVTEAGTMNIFFLIRNEQGVKQLITPSLKDGTILPGVTRQSVIELSQQWNECETVEKMIPFAEIKAAFERGDVLEIFGTGTAAVIQPINGIVYEGKEYKPVVPFDDSMLQVRLTNFLIGVQYGDIDHPWSHVVPPSTTWSKPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1K0</accession>
    <name>A4S1K0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419162.1">
        <property type="nucleotide sequence ID" value="XM_001419125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1K0"/>
    <dbReference type="GeneID" id="5003218"/>
    <dbReference type="Gramene" id="ABO97455">
        <property type="protein sequence ID" value="ABO97455"/>
        <property type="gene ID" value="OSTLU_33127"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33127"/>
    <dbReference type="HOGENOM" id="CLU_2430997_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="91" mass="9432" checksum="64DE93C98A85510E" modified="2007-05-15" version="1">MSIAFRARTSSAVVGVACALCAASHVRVVDARTARDVFGTARDASTSSETPGERGEAILGRAARREIGRAWNAAIDGAFGAGVRALSERKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1M0</accession>
    <name>A4S1M0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419174.1">
        <property type="nucleotide sequence ID" value="XM_001419137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1M0"/>
    <dbReference type="STRING" id="436017.A4S1M0"/>
    <dbReference type="GeneID" id="5003173"/>
    <dbReference type="Gramene" id="ABO97467">
        <property type="protein sequence ID" value="ABO97467"/>
        <property type="gene ID" value="OSTLU_33146"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33146"/>
    <dbReference type="eggNOG" id="KOG2184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073440_0_0_1"/>
    <dbReference type="OrthoDB" id="551361at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47423">
        <property type="entry name" value="G-PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47423:SF2">
        <property type="entry name" value="PROTEIN SQS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="200"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="244" mass="26974" checksum="DB4F9FBDB374EE46" modified="2007-05-15" version="1">MPGEKKMLKKLHVAATRATRARRDGFDANDARREMERVVREGKSLTIVCSKRACVARGQGRVIRALAAALGTTFRPTRAGKRAAFVIERVDGTSDVPPVVSEELLKSLCAEPMTRDEYLMSDERRARLEKRAEASRRANKGKKKKDRGRRWNRKSDEEDTTRDIVEFTRATEDEATFDEDAARRAPSPLSGAFAAFEAHTRGIGSRLLTAMGFTRGSGLGRDNQGIAEAPRAESRAKRAGLGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1U5</accession>
    <name>A4S1U5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF1640-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_42864</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419428.1">
        <property type="nucleotide sequence ID" value="XM_001419391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1U5"/>
    <dbReference type="STRING" id="436017.A4S1U5"/>
    <dbReference type="GeneID" id="5003206"/>
    <dbReference type="Gramene" id="ABO97721">
        <property type="protein sequence ID" value="ABO97721"/>
        <property type="gene ID" value="OSTLU_42864"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42864"/>
    <dbReference type="eggNOG" id="KOG3156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063283_4_0_1"/>
    <dbReference type="OMA" id="MCSSTHN"/>
    <dbReference type="OrthoDB" id="889336at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024461">
        <property type="entry name" value="CCDC90-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360:SF1">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07798">
        <property type="entry name" value="CCDC90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15915" checksum="D0B3B71B3327C33D" modified="2007-05-15" version="1">MTRAGFVARNELERELMHGRAETQALKQEVASSLREASASMKHSTETLQAENEKLRADLKYNIDRITQSQKLDLNLEKGRLRELHGIQESQMKEVEARVDRELHQMRTQIEAAKTEIIRYSVGTLVSLGALSLAAIRLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1V9</accession>
    <name>A4S1V9_OSTLU</name>
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        <recommendedName>
            <fullName evidence="6">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_42712</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ABO97727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="5003212"/>
    <dbReference type="Gramene" id="ABO97727">
        <property type="protein sequence ID" value="ABO97727"/>
        <property type="gene ID" value="OSTLU_42712"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42712"/>
    <dbReference type="eggNOG" id="KOG2667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034705_3_0_1"/>
    <dbReference type="OMA" id="GNFHVHL"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
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        <property type="entry name" value="Erv_N"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
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    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
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        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF37">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE 5-3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="469"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="145"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO97727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="513" mass="57212" checksum="BB380A15111FCDAD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S314</accession>
    <name>A4S314_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_33640</name>
    </gene>
    <organism evidence="6 7">
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S314"/>
    <dbReference type="STRING" id="436017.A4S314"/>
    <dbReference type="GeneID" id="5003505"/>
    <dbReference type="Gramene" id="ABO98131">
        <property type="protein sequence ID" value="ABO98131"/>
        <property type="gene ID" value="OSTLU_33640"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33640"/>
    <dbReference type="eggNOG" id="KOG0773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1716295_0_0_1"/>
    <dbReference type="OMA" id="GITKCAR"/>
    <dbReference type="OrthoDB" id="10056939at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
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        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="5">
        <location>
            <begin position="64"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="66"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="153" mass="17674" checksum="19533FEB4749942C" modified="2007-05-15" version="1">MRDDALAAYERRLDDVERRFETLRAKMELTLPSGITKCARSGIRAAFASARLRAEKARAVASRDAEPRRRRLGSKEGQRVLRSWILAHFDHPFPTREEKRRLAREIGSSEFAIGNFFINARARFHKPLVMALADELEREGVDVLNARDEERVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S325</accession>
    <name>A4S325_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_16890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419845.1">
        <property type="nucleotide sequence ID" value="XM_001419808.1"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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        </location>
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        </location>
    </feature>
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        <location>
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        </location>
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        <location>
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            <end position="761"/>
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    </feature>
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        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1200"/>
            <end position="1210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1321" mass="147133" checksum="103194FA47A4E96B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S389</accession>
    <name>A4S389_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenoprotein S</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S389"/>
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    <dbReference type="Gramene" id="ABO98168">
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        <property type="gene ID" value="OSTLU_94781"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94781"/>
    <dbReference type="HOGENOM" id="CLU_1707246_0_0_1"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
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        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="16748" checksum="DA9F23CB519CFA45" modified="2007-05-15" version="1">MWTAYARVASVVENALGINFHAFVACVTLVIALTYPKLAKSVSDRLDSRAMNDRERLERYQRNRQRALEKREEELRRAASETKGGKAELDRAAALEAKLAEIDAKAARLGLTANGKGRKLGDSGPSRPEWNPLMGGGASRGYRPTGRPRPGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3D0</accession>
    <name>A4S3D0_OSTLU</name>
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        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419898.1">
        <property type="nucleotide sequence ID" value="XM_001419861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3D0"/>
    <dbReference type="GeneID" id="5004133"/>
    <dbReference type="Gramene" id="ABO98191">
        <property type="protein sequence ID" value="ABO98191"/>
        <property type="gene ID" value="OSTLU_26012"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26012"/>
    <dbReference type="HOGENOM" id="CLU_1055205_0_0_1"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="23"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="264" mass="27650" checksum="A42AA70BE5A4D977" modified="2007-05-15" version="1">MTLVVITGPCAGREFELRRDGESAIGRTKRGNAVWIKGDGAVSQSHATCRWCAKREAWTISDAGSSNGTEVDGKDVEEGGEGATLRDGSVIKLGTETTVVCRTRAADERGEAGTVGEEEDEENGNRENAVVVNEGGRGAVGDGGKASAAKTKSGKRDAYAFDLDEPKSVTKVAAARKRAKATTVTAKQAHESTTAASETAEVATKAESRAAAEVGFDVPTVHEYATAQLERLQAVIRADARASVEAFRADARGLLADLLQDIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3L9</accession>
    <name>A4S3L9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphatidylinositol N-acetylglucosaminyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_93333</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419943.1">
        <property type="nucleotide sequence ID" value="XM_001419906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3L9"/>
    <dbReference type="STRING" id="436017.A4S3L9"/>
    <dbReference type="GeneID" id="5004071"/>
    <dbReference type="Gramene" id="ABO98236">
        <property type="protein sequence ID" value="ABO98236"/>
        <property type="gene ID" value="OSTLU_93333"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93333"/>
    <dbReference type="eggNOG" id="KOG3059">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024002_2_0_1"/>
    <dbReference type="OrthoDB" id="196709at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009450">
        <property type="entry name" value="Plno_GlcNAc_GPI2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06432">
        <property type="entry name" value="GPI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="34615" checksum="3D0DF91C811E17B9" modified="2007-05-15" version="1">MPRDDARARDYRVLYDRDARALRDNHTDPRTFLARMRLNKSVKTRSFATSARAAWTISQQCAVVVIHSGAHGAIADGAVRARTLVRWETRALGVGLAAWALGGDGSSAEGSVKLGRAGRAWRSIRLGALTLGGLVALTPLCQTMTAAVSDDTAATCATLALALYAITYDYAFVNLETKQLASSFSLGASMFASLLMASRLDDPASVFADVLLALECYVLSPYVWRAIRAFSTTLHLVVVFALHIIAFTVARARDETLAWAYVVGVFLLAVVAPASLVRLAASGKRQIAGPWDEALPKLYLFKDTVRAAGVPRYRHWAANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3M2</accession>
    <name>A4S3M2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metal-dependent protein hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419945.1">
        <property type="nucleotide sequence ID" value="XM_001419908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3M2"/>
    <dbReference type="STRING" id="436017.A4S3M2"/>
    <dbReference type="GeneID" id="5004072"/>
    <dbReference type="Gramene" id="ABO98238">
        <property type="protein sequence ID" value="ABO98238"/>
        <property type="gene ID" value="OSTLU_26102"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26102"/>
    <dbReference type="eggNOG" id="KOG2948">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051576_0_0_1"/>
    <dbReference type="OMA" id="FHCDEVV"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="37706" checksum="532C71A6FF33AFC2" modified="2007-05-15" version="1">MTNEAKRTKAQTTIATHDGAFHCDEALGCHLLRRTRAFAGAAIDRSRDGERWAKADVVIDVGAVYDAEKRLYDHHQREFAETFGRGFGTKLSSAGLVYKHYGEEIVREALTRAKRGEAPDEKTVEKIYVKMYEEFIEGVDAIDNGVNMYDTDAKAKYKDNTGLSARVKRLNPAWDEPNSPEKQMEQFEKAVALTGGEFDDVLEYYASKWLPARSHVESALDKAKSVHESGEILYLETFCPWKEHLYELEAERQMTTLPKFVLWQDPKGFRVSTISLSPSSFEFRKGLPTAWRGLRDDDLSKASGIPGCVFIHAAGFIGGNATYDGALAMAVAGLQMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3S7</accession>
    <name>A4S3S7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419972.1">
        <property type="nucleotide sequence ID" value="XM_001419935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3S7"/>
    <dbReference type="STRING" id="436017.A4S3S7"/>
    <dbReference type="GeneID" id="5004155"/>
    <dbReference type="Gramene" id="ABO98265">
        <property type="protein sequence ID" value="ABO98265"/>
        <property type="gene ID" value="OSTLU_94868"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94868"/>
    <dbReference type="HOGENOM" id="CLU_2339734_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="98" mass="10321" checksum="B83A988367D17C2A" modified="2007-05-15" version="1" fragment="single">MSSSSDDGDGAPSEIWGGQRNASEAKTPRRKARTKAERDASAESYEWSAWASSCGIISIAITATYFRILREVDVNGGLFPVAELVAQLALIAGAAVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3W8</accession>
    <name>A4S3W8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipase/carboxylesterase/thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_93362</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419993.1">
        <property type="nucleotide sequence ID" value="XM_001419956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3W8"/>
    <dbReference type="STRING" id="436017.A4S3W8"/>
    <dbReference type="GeneID" id="5004175"/>
    <dbReference type="Gramene" id="ABO98286">
        <property type="protein sequence ID" value="ABO98286"/>
        <property type="gene ID" value="OSTLU_93362"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93362"/>
    <dbReference type="eggNOG" id="KOG2112">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085544_0_0_1"/>
    <dbReference type="OMA" id="RAWFKPR"/>
    <dbReference type="OrthoDB" id="2418081at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF17">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="4">
        <location>
            <begin position="67"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="284" mass="31021" checksum="F0048B28BFF87375" modified="2007-05-15" version="1">MGFDARASTRDDATSDARDVERVVRRVNRRISSAVGAFGSDATGPRDVEGEGGRRGATREATRDAGAARLLVWFHGYGDVDGGAWREFCEVVARARGSASGRTAIATPDAMRMDAGNGRFPRAWFKPRLRVRRKDEREWTCDGIEDAVVRAVTIVDDAVRKYGIQRKDVVLGGFSQGACLALACAKSELSDVGGVLAVRGYLPNRSREFSELKPDTLILAGGADPLVPVEWSLEAGRLTGGMVTLRENMGHELCVEDVYRARRWFHERAVANGNCIANHTRLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S407</accession>
    <name>A4S407_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_8538</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420187.1">
        <property type="nucleotide sequence ID" value="XM_001420150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S407"/>
    <dbReference type="STRING" id="436017.A4S407"/>
    <dbReference type="GeneID" id="5003972"/>
    <dbReference type="Gramene" id="ABO98480">
        <property type="protein sequence ID" value="ABO98480"/>
        <property type="gene ID" value="OSTLU_8538"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8538"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_4_2_1"/>
    <dbReference type="OMA" id="CCQFFIC"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000013">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF558">
        <property type="entry name" value="YCF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="16"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="163" mass="17400" checksum="52A492752FF83C18" modified="2007-05-15" version="1" fragment="single">PKVYFDMQIGRGARATKLGRIVFELRSDATPKTAENFKVLCEKPEGEGYVGSRFHRVIPSFMCQGGDFTADNGTGGRSIYGRNFPDENFTLKHEGPGILSMANAGPNTNGSQFFICTVATPFLNGKHTVFGQVIEGMSVVKAIESVGSRGGETAADVIIGDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S412</accession>
    <name>A4S412_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_37894</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420191.1">
        <property type="nucleotide sequence ID" value="XM_001420154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S412"/>
    <dbReference type="STRING" id="436017.A4S412"/>
    <dbReference type="GeneID" id="5003976"/>
    <dbReference type="Gramene" id="ABO98484">
        <property type="protein sequence ID" value="ABO98484"/>
        <property type="gene ID" value="OSTLU_37894"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37894"/>
    <dbReference type="eggNOG" id="ENOG502QRQR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_579254_0_0_1"/>
    <dbReference type="OMA" id="HADGENC"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005747">
        <property type="entry name" value="MutS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01069">
        <property type="entry name" value="mutS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48466:SF2">
        <property type="entry name" value="OS10G0509000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48466">
        <property type="entry name" value="OS10G0509000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="4">
        <location>
            <begin position="213"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="502" mass="54193" checksum="378439E977A897D7" modified="2007-05-15" version="1" fragment="single">MRTPLEVVEAIERCVSVPGGEVLDAASETLRAIRVEQRRIREELRTMLNATSKEMARKNFAERAQIVTRLGRQCIPMKLGSAGELPGVVLDVSGTGNTVFKEPQIAVPLNNALATLSASEDAEIERILVELTSIVQTHADVLLDANEALTELDVANARARHAEWFDGAEPTIVDANQGMCVRELQHPLFRHWRRGTDVRDVVVPIDFNVDSSIKCVTITGPNTGGKTASLKAIGVACLMARAGLYLPCESGCEIPFFRHVIADLGDSQTLELDGGLSTFGAHLKGLQRILDAATDDTLVLLDEPGSGTDPAEGASLAVAVLNKLSRTSRLTIATSHYEEVKEATLASDTAQVAAVEFDLQSLQPTYRLLWGETGKSNALHIAAGLGLEPWILAEARIALAKADANAEVDASGAIARENRAKLASALDEECDVQLARRAAAAATLEETRALFDEVRSKSAHLDLRKQIIRDDANNEIERKIEEARDGLSRALRTLNVATPNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4S449</accession>
    <name>A4S449_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycine cleavage system P protein</fullName>
            <ecNumber evidence="8">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_26284</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="8"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420206.1">
        <property type="nucleotide sequence ID" value="XM_001420169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S449"/>
    <dbReference type="STRING" id="436017.A4S449"/>
    <dbReference type="GeneID" id="5004183"/>
    <dbReference type="Gramene" id="ABO98499">
        <property type="protein sequence ID" value="ABO98499"/>
        <property type="gene ID" value="OSTLU_26284"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26284"/>
    <dbReference type="eggNOG" id="KOG2040">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_3_2_1"/>
    <dbReference type="OMA" id="RNLICTC"/>
    <dbReference type="OrthoDB" id="6537869at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016594">
        <property type="term" value="F:glycine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000005">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000007">
        <property type="entry name" value="glycine dehydrogenase (Decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000007">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049316">
        <property type="entry name" value="GDC-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049315">
        <property type="entry name" value="GDC-P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003346">
        <property type="entry name" value="PRK04366.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773:SF1">
        <property type="entry name" value="GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="GLYCINE DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21478">
        <property type="entry name" value="GcvP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="9">
        <location>
            <begin position="487"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="793"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="976" mass="105656" checksum="802FB98B5587B553" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4E4</accession>
    <name>A4S4E4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420252.1">
        <property type="nucleotide sequence ID" value="XM_001420215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4E4"/>
    <dbReference type="GeneID" id="5004452"/>
    <dbReference type="Gramene" id="ABO98545">
        <property type="protein sequence ID" value="ABO98545"/>
        <property type="gene ID" value="OSTLU_93415"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93415"/>
    <dbReference type="HOGENOM" id="CLU_1135105_0_0_1"/>
    <dbReference type="OMA" id="GTIMATC"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43019:SF23">
        <property type="entry name" value="PROTEASE DO-LIKE 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43019">
        <property type="entry name" value="SERINE ENDOPROTEASE DEGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="25556" checksum="42A47CA49F36EBBF" modified="2007-05-15" version="1">MSAPVDVARAAAARVRADASSTSRAGSGVVVRHRGVACVLTAAHVASFAGAKNALRVELASGAARRGRVVGVHDALDLAVVYLDGDLDGAATMEPGEARVGDEARALGTAQRYAAATAACADAIRGRRETGRVLKIHRDDRGDDTHAMHDARVLAGQSGGALVRETDGKLLGVHSFGDAFWGGSRDVCVLVNAATLDAIEIARDGVDPEVYATARVNAMIFRSSDEALKRMAPELSAKQRASWIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4I7</accession>
    <name>A4S4I7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_6946</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420272.1">
        <property type="nucleotide sequence ID" value="XM_001420235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4I7"/>
    <dbReference type="STRING" id="436017.A4S4I7"/>
    <dbReference type="GeneID" id="5004475"/>
    <dbReference type="Gramene" id="ABO98565">
        <property type="protein sequence ID" value="ABO98565"/>
        <property type="gene ID" value="OSTLU_6946"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6946"/>
    <dbReference type="eggNOG" id="KOG0324">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069001_0_2_1"/>
    <dbReference type="OMA" id="RTECSAH"/>
    <dbReference type="OrthoDB" id="412286at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF9">
        <property type="entry name" value="OS06G0107000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="4">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="175" mass="18735" checksum="758DB703127557C2" modified="2007-05-15" version="1" fragment="single">MALVTLSVYDIKHAENARISSAVTSLNTLTRNALNVGGIFHGGVEVFGDEWSFGYCPEGSGVYRCNPRMNPMYEYRESVPLGVTSLSPARASAAVAALRAQWRGSDYEVLERNCNHFCEALCEALGCEGPPEWLNAFANNANKARGAYQSAVSGVESAYESAVSGVAGAWAWLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4I9</accession>
    <name>A4S4I9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FBP65</name>
        <name evidence="10" type="ORF">OSTLU_26425</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 7"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420445.1">
        <property type="nucleotide sequence ID" value="XM_001420408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4I9"/>
    <dbReference type="STRING" id="436017.A4S4I9"/>
    <dbReference type="GeneID" id="5004342"/>
    <dbReference type="Gramene" id="ABO98738">
        <property type="protein sequence ID" value="ABO98738"/>
        <property type="gene ID" value="OSTLU_26425"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26425"/>
    <dbReference type="eggNOG" id="KOG0543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_13_4_1"/>
    <dbReference type="OMA" id="HAFGANE"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF9">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="9">
        <location>
            <begin position="39"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="505"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO98738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="542" mass="58430" checksum="F12554B7801A452F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5C0</accession>
    <name>A4S5C0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">NADH-quinone oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_39049</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420747.1">
        <property type="nucleotide sequence ID" value="XM_001420710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5C0"/>
    <dbReference type="STRING" id="436017.A4S5C0"/>
    <dbReference type="GeneID" id="5004846"/>
    <dbReference type="Gramene" id="ABO99040">
        <property type="protein sequence ID" value="ABO99040"/>
        <property type="gene ID" value="OSTLU_39049"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39049"/>
    <dbReference type="eggNOG" id="KOG2282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_11_6_1"/>
    <dbReference type="OMA" id="QAMAYGV"/>
    <dbReference type="OrthoDB" id="10249365at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.740:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.210:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="11">
        <location>
            <begin position="10"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="13">
        <location>
            <begin position="88"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="12">
        <location>
            <begin position="225"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO99040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="685" mass="73696" checksum="AD184030BED4205A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5G8</accession>
    <name>A4S5G8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="3 7">4.2.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_5668</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>hydroxymethylbilane = uroporphyrinogen III + H2O</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="3 7"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420605.1">
        <property type="nucleotide sequence ID" value="XM_001420568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5G8"/>
    <dbReference type="STRING" id="436017.A4S5G8"/>
    <dbReference type="GeneID" id="5004604"/>
    <dbReference type="Gramene" id="ABO98898">
        <property type="protein sequence ID" value="ABO98898"/>
        <property type="gene ID" value="OSTLU_5668"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5668"/>
    <dbReference type="eggNOG" id="ENOG502QST9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_9_2_1"/>
    <dbReference type="OMA" id="WVESIME"/>
    <dbReference type="OrthoDB" id="443551at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042:SF1">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole biosynthesis uroporphyrinogen III synthase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="26428" checksum="FACE70EEAE691BB3" modified="2007-05-15" version="1" fragment="single">VVCTRERGKNGALMNLLAARGARCVELPLVEAVPGEDAATFPDVLKRESWDWVCVTSPEAAKVFLEAYERAGRPSGVRVAVVGAGTGKVLAKAEPTTFAMDKQFTPSKATAATMAAELPCDQGSLILYPASKKAATTLQDGLEARGATVVRLNTYSTERVERLSPEDVAAAVRADVVTFGSPSAVRAWVELCGDALYERLTADARALQPAYVCIGETSAEACANCELPDVFYPELPGIEGWAETVFLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5I1</accession>
    <name>A4S5I1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative mitochondrial ribosomal protein L27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MRPL27</name>
        <name evidence="5" type="ORF">OSTLU_39278</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420777.1">
        <property type="nucleotide sequence ID" value="XM_001420740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5I1"/>
    <dbReference type="STRING" id="436017.A4S5I1"/>
    <dbReference type="GeneID" id="5004643"/>
    <dbReference type="Gramene" id="ABO99070">
        <property type="protein sequence ID" value="ABO99070"/>
        <property type="gene ID" value="OSTLU_39278"/>
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    <dbReference type="KEGG" id="olu:OSTLU_39278"/>
    <dbReference type="eggNOG" id="KOG4600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095424_1_0_1"/>
    <dbReference type="OrthoDB" id="1867012at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="50S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_bL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_bL27_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="14391" checksum="71B5F7E0577331BA" modified="2007-05-15" version="1">MLRARARALASSTARATIAEEGARAWRAATQTIFVRFASKKQGGSSSNGRDSNPKFLGLKRGDGEVVRPGHVLARQRGTKWHPGTNCGIGKDHTLFALVQGKVCFSTDKHRGRKLINVAPLSKTHPKYVEGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S636</accession>
    <name>A4S636_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25364</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420877.1">
        <property type="nucleotide sequence ID" value="XM_001420840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S636"/>
    <dbReference type="GeneID" id="5004866"/>
    <dbReference type="Gramene" id="ABO99170">
        <property type="protein sequence ID" value="ABO99170"/>
        <property type="gene ID" value="OSTLU_25364"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25364"/>
    <dbReference type="HOGENOM" id="CLU_1285145_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="256" mass="28863" checksum="424122A8F746A4FE" modified="2007-05-15" version="1">MGGSLSAPAFYHPDLLAVLQCQKKIPIDFVSRDVPSWHIAPLLETHTHIKAPHRPASHSVMTDSVACDVPLYQRHVAQLAEVPSKRPRDPDWSRNSPVANELVDILNGALQDMGGWPICETIRCLCCSVSGPVRNTPPQMVEAFKKVCQQVNEAKLFNMGLQCRAGMYKIERKAGEGVAEVNEFCVLVEKRDDEKLRNVEALDTLEYIRSLKLSPGWEPRDWRDHHAVVTGWSPPANWMARCYDFPTPSYETTNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4S659</accession>
    <name>A4S659_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CHB3501</name>
        <name evidence="11" type="ORF">OSTLU_17735</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420888.1">
        <property type="nucleotide sequence ID" value="XM_001420851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S659"/>
    <dbReference type="STRING" id="436017.A4S659"/>
    <dbReference type="GeneID" id="5005065"/>
    <dbReference type="Gramene" id="ABO99181">
        <property type="protein sequence ID" value="ABO99181"/>
        <property type="gene ID" value="OSTLU_17735"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17735"/>
    <dbReference type="eggNOG" id="KOG1279">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_285039_0_0_1"/>
    <dbReference type="OMA" id="TIDMPDP"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049898">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032451">
        <property type="entry name" value="SMARCC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887:SF41">
        <property type="entry name" value="THIOREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16495">
        <property type="entry name" value="SWIRM-assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52032">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Chromo" evidence="10">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="8">
        <location>
            <begin position="248"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="497"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="9">
        <location>
            <begin position="500"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="902" mass="99948" checksum="9856917D4705895D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S671</accession>
    <name>A4S671_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GTB3501</name>
        <name evidence="10" type="ORF">OSTLU_51236</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPT6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420894.1">
        <property type="nucleotide sequence ID" value="XM_001420857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S671"/>
    <dbReference type="STRING" id="436017.A4S671"/>
    <dbReference type="GeneID" id="5005071"/>
    <dbReference type="Gramene" id="ABO99187">
        <property type="protein sequence ID" value="ABO99187"/>
        <property type="gene ID" value="OSTLU_51236"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51236"/>
    <dbReference type="eggNOG" id="KOG1856">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001680_2_0_1"/>
    <dbReference type="OMA" id="NINCALI"/>
    <dbReference type="OrthoDB" id="995477at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09928">
        <property type="entry name" value="SH2_Cterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09918">
        <property type="entry name" value="SH2_Nterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2740">
        <property type="entry name" value="Spt6, Death-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.850">
        <property type="entry name" value="Spt6, helix-hairpin-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049540">
        <property type="entry name" value="Spt6-like_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042066">
        <property type="entry name" value="Spt6_death-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032706">
        <property type="entry name" value="Spt6_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035420">
        <property type="entry name" value="Spt6_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035018">
        <property type="entry name" value="Spt6_SH2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035019">
        <property type="entry name" value="Spt6_SH2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028231">
        <property type="entry name" value="Spt6_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017072">
        <property type="entry name" value="TF_Spt6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145:SF6">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14635">
        <property type="entry name" value="HHH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14633">
        <property type="entry name" value="SH2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21710">
        <property type="entry name" value="Spt6_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14639">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158832">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Transcription elongation factor Spt6 YqgF" evidence="8">
        <location>
            <begin position="529"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription elongation factor Spt6 helix-hairpin-helix motif" evidence="7">
        <location>
            <begin position="681"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Spt6-like S1/OB" evidence="9">
        <location>
            <begin position="891"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="domain" description="Spt6 SH2" evidence="6">
        <location>
            <begin position="1020"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1245" mass="139052" checksum="A102E906973290F8" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S682</accession>
    <name>A4S682_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-oxoadipate dioxygenase/decarboxylase</fullName>
            <ecNumber evidence="6">1.13.11.93</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2-hydroxyglutarate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_5707</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.93" evidence="6"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421045.1">
        <property type="nucleotide sequence ID" value="XM_001421008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S682"/>
    <dbReference type="GeneID" id="5005107"/>
    <dbReference type="Gramene" id="ABO99338">
        <property type="protein sequence ID" value="ABO99338"/>
        <property type="gene ID" value="OSTLU_5707"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5707"/>
    <dbReference type="eggNOG" id="ENOG502QTNU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053061_1_0_1"/>
    <dbReference type="OMA" id="HEDYGVE"/>
    <dbReference type="OrthoDB" id="1908993at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009770">
        <property type="entry name" value="HGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31136:SF5">
        <property type="entry name" value="2-OXOADIPATE DIOXYGENASE_DECARBOXYLASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31136">
        <property type="entry name" value="DUF1338 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07063">
        <property type="entry name" value="HGLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01150">
        <property type="entry name" value="DUF1338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="257" mass="29319" checksum="007FB949A757447D" modified="2007-05-15" version="1" fragment="single">DHIAYRSFAHEDYGVEGVCEVFERLGWETVSASEGGRLEFTEKRVRARWMKPPKTPRGETPLPRIFVSELVVDACDEELKGYLTQHFERVGEGKVLRSMEWAKGRNARWQLPPASVYAKVERLSEYASWTLLHGYAVNHVALSLFQLRKMYPETPLRTLEDLETSFASNAAFSRIRWNESGGRIKRSPSGLLAQSALMSEDHEDTFKDYGLPGSYVEFVQRLPKPQNADKSFEELQECDLREGFEAGNASKIFDSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6P1</accession>
    <name>A4S6P1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Possible early light inducible or carotene biosynthesis related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CBR13a</name>
        <name evidence="5" type="synonym">CBR21b</name>
        <name evidence="4" type="synonym">ELIP</name>
        <name evidence="4" type="ORF">OSTLU_27189</name>
        <name evidence="5" type="ORF">OSTLU_29720</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6P1"/>
    <dbReference type="STRING" id="436017.A4S6P1"/>
    <dbReference type="Gramene" id="ABO99275">
        <property type="protein sequence ID" value="ABO99275"/>
        <property type="gene ID" value="OSTLU_27189"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01271">
        <property type="protein sequence ID" value="ABP01271"/>
        <property type="gene ID" value="OSTLU_29720"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27189"/>
    <dbReference type="KEGG" id="olu:OSTLU_29720"/>
    <dbReference type="eggNOG" id="ENOG502SY8D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1216207_0_0_1"/>
    <dbReference type="OMA" id="FEIFIVV"/>
    <dbReference type="OrthoDB" id="498150at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP01271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23136" checksum="49ABAF1C546235AD" modified="2007-05-15" version="1">MFAVTTRPQLAARAVVKTQRAHRRASVAVRAENDVSKAVEEANSEWKDADAASKQPTMRVDAIDPADGSIAEAAPLGNDNSMLDSVMLAFKDSRAVETINGRAAMIGWTAALYVELTSNTSFMHQLFNERTFTLADGITRTSTYPAAGFFLVPACVILTLASSLAPALKKSSPNGLDEAPEAFGPFRAEAEMTNGRGAMIGLVALPIVEKIMGGSALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S744</accession>
    <name>A4S744_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421389.1">
        <property type="nucleotide sequence ID" value="XM_001421352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S744"/>
    <dbReference type="GeneID" id="5005393"/>
    <dbReference type="Gramene" id="ABO99682">
        <property type="protein sequence ID" value="ABO99682"/>
        <property type="gene ID" value="OSTLU_27346"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27346"/>
    <dbReference type="eggNOG" id="ENOG502SPFS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_843048_0_0_1"/>
    <dbReference type="OrthoDB" id="498371at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="38011" checksum="74278CD6C86E0F92" modified="2007-05-15" version="1">MEFDEEEPRRQNEVYDALIRELVRVPDDVRDAVASFLQDLRRDGVDWYRVGDGGEFDDKESWRVGDGGEFDDKESFFRTVHAGACMRAARIMGSGCLKFAREHVAPWDEWTCAIAAYYGNLDCLKYAHENGCPWNENTCIAAAWNGHLDCLKYAHEHGYPWNERTCASAAWKGHLDCLKYAHEQGCDWDAWTCDNAADGGHLECLKYAHERGCDWDERTCASAAWEGHLDCLKYAHENGCDWNETMCASAAWKGHLDCLKYACACECPGSDRYAEALNEVVVPVVDERFGVEVALAFHRNGGEISMREFLPLWVAHREGYRDAHLEVARNVSNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4S763</accession>
    <name>A4S763_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421399.1">
        <property type="nucleotide sequence ID" value="XM_001421362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S763"/>
    <dbReference type="STRING" id="436017.A4S763"/>
    <dbReference type="GeneID" id="5005485"/>
    <dbReference type="Gramene" id="ABO99692">
        <property type="protein sequence ID" value="ABO99692"/>
        <property type="gene ID" value="OSTLU_27365"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27365"/>
    <dbReference type="eggNOG" id="KOG0123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_15_7_1"/>
    <dbReference type="OMA" id="KGWGIVE"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="112"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="209"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="288" mass="31060" checksum="79A2909CD1E25000" modified="2007-05-15" version="1">MDVDGGSSARLYVGNIPWSTTIEDLRELFAECGGVTRVDIPTGRQGRSRGYGLVEFNSEAEAQAAVTRMDGTPLGDRTITVREDKAPTKAAGGAKKASASVLGDAPAGGDGCRCYFGNLAWETSEETLTSHCASFGVNVVQCEVARQSGGRSKGWALVDFATPEEAQNAIEQMHNSEIQGRSIIVRVERPGAGQKSARVETRPENSSGLQIVVRNLPWTTTSEDLRQVFQQVGNVVNAVAVCHTDTGRSKGWGTVLFETREQAQAAIQGFNGVELEHRPMQIKLDRYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S836</accession>
    <name>A4S836_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_18265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421692.1">
        <property type="nucleotide sequence ID" value="XM_001421655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S836"/>
    <dbReference type="STRING" id="436017.A4S836"/>
    <dbReference type="GeneID" id="5005829"/>
    <dbReference type="Gramene" id="ABO99985">
        <property type="protein sequence ID" value="ABO99985"/>
        <property type="gene ID" value="OSTLU_18265"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18265"/>
    <dbReference type="eggNOG" id="KOG0450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1158936_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="240" mass="26385" checksum="3CFAC749AE7F2B8A" modified="2007-05-15" version="1" fragment="single">MSTRRATSALARALDRARAADAGARGARGNGNPPTLTVIARRASSTTASTTASTGANDDGDRFDDVTDALALTELTRAVRARGHLTAALDPLGRSLGPIVRGYETMEATTPKDARDIHALLQGYPDHFYKEDCKTKVSLGEYLGLSESARRAPEKRFHLGEDAATLDPSGARAKTAWRVDELFERLRDVYCGTMSVECNHLTSKERKRWLREQVECGPREASATERRRTLERLLTADRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S865</accession>
    <name>A4S865_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421709.1">
        <property type="nucleotide sequence ID" value="XM_001421672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S865"/>
    <dbReference type="GeneID" id="5005610"/>
    <dbReference type="Gramene" id="ABP00003">
        <property type="protein sequence ID" value="ABP00003"/>
        <property type="gene ID" value="OSTLU_27740"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27740"/>
    <dbReference type="HOGENOM" id="CLU_304972_0_0_1"/>
    <dbReference type="OMA" id="KSTHALP"/>
    <dbReference type="OrthoDB" id="10403966at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1071" mass="116659" checksum="26A40C0F02C0F912" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Q2</accession>
    <name>A4S8Q2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PCIF1 WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421800.1">
        <property type="nucleotide sequence ID" value="XM_001421763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Q2"/>
    <dbReference type="GeneID" id="5005778"/>
    <dbReference type="Gramene" id="ABP00094">
        <property type="protein sequence ID" value="ABP00094"/>
        <property type="gene ID" value="OSTLU_27929"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27929"/>
    <dbReference type="eggNOG" id="ENOG502QVT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_693339_0_0_1"/>
    <dbReference type="OMA" id="FASPMNA"/>
    <dbReference type="OrthoDB" id="567664at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016422">
        <property type="term" value="F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099122">
        <property type="term" value="F:RNA polymerase II C-terminal domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039881">
        <property type="entry name" value="PCIF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022035">
        <property type="entry name" value="PCIF1_WW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727:SF0">
        <property type="entry name" value="MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727">
        <property type="entry name" value="PHOSPHORYLATED CTD INTERACTING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12237">
        <property type="entry name" value="PCIF1_WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCIF1 WW" evidence="1">
        <location>
            <begin position="165"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="398" mass="43446" checksum="A7BF61D32FB48B05" modified="2007-05-15" version="1">MKRVREAFRAACERRGGLEAPPQLALERWRFATKLAEEARGRTAAAAGKGKTKRRRRGACGLVGENTDAMFPNVAHDGATKGTMANDLMRAGVSEAIAIEIEASVCAASAKEVVALEAMKQKLVDGGAHGLAKLAATKLTIHKHSRDLTLGDDYLVKLTHEAYGKLRALYEKHSRAGGDDDGDDDVHDRMFALLLRYKTIHGHGFQAACSHDVFRVLHDDLKVTMECFASPMNAYFARFCSAFGDVDAPFGSIGSFAAFQPSRGSYEVNPPFVREVLDEAALWCEALLERAEKSQNALTFVFIMPGWKETGAFDALTNSAFLRANVLIAAVDHGYCDGASHQRRDPYRASPYDTCVFVLQSSKAARDVGVKDTFATSVRVAMARAVPTLAQLKRQKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Q7</accession>
    <name>A4S8Q7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421670.1">
        <property type="nucleotide sequence ID" value="XM_001421633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Q7"/>
    <dbReference type="GeneID" id="5005805"/>
    <dbReference type="Gramene" id="ABO99963">
        <property type="protein sequence ID" value="ABO99963"/>
        <property type="gene ID" value="OSTLU_27934"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27934"/>
    <dbReference type="HOGENOM" id="CLU_592313_0_0_1"/>
    <dbReference type="OMA" id="RTIDCEA"/>
    <dbReference type="OrthoDB" id="10459618at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="391" mass="43425" checksum="5FB316448FB55B16" modified="2007-05-15" version="1">MWVDAVERVVAADAEDDAEGVETTAATRGRWIPTKARVGGDFDVGEESDDAEREDAEASSDADDAYEANATLRALDDEVWIENYGQAKRRRARAKFLRAHGVDPKTTSGTAAFAALGATRDDCPAAYFAPKVGAASLGGPGASELPEHFAKFSVHATKLAALADQIYILCTECSLGIPEDWRAKTSFVHGFRIDECLKTQGIDHWHKASFSHAHALMDAQKKQHKTVAIIEEDVITRDFADGGVGWRMLLDNLGHVRDTMRLEKDWRTIRVGYRAMFIDRSIESVSKLEGKETCPKDCRCEKKNAFTCIMRQSGCDMRSSDFYLVREAAYQPIIDKIYEGYTVDCEALREVPNQIYITPQLSFQGTLDLKLQTQIQMGEEFMQKCAVGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9B1</accession>
    <name>A4S9B1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_89440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422032.1">
        <property type="nucleotide sequence ID" value="XM_001421995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9B1"/>
    <dbReference type="STRING" id="436017.A4S9B1"/>
    <dbReference type="GeneID" id="5005934"/>
    <dbReference type="Gramene" id="ABP00326">
        <property type="protein sequence ID" value="ABP00326"/>
        <property type="gene ID" value="OSTLU_89440"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89440"/>
    <dbReference type="eggNOG" id="ENOG502QVC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060054_0_0_1"/>
    <dbReference type="OMA" id="NPAGFCI"/>
    <dbReference type="OrthoDB" id="201720at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009704">
        <property type="term" value="P:de-etiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904143">
        <property type="term" value="P:positive regulation of carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15852">
        <property type="entry name" value="PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15852:SF8">
        <property type="entry name" value="PROTEIN ORANGE-LIKE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="294" mass="32055" checksum="BA1D252485F9050C" modified="2007-05-15" version="1">MRAKASRTARAEWARTRAGGTRRAIGEGEGEGAATTAANDDAEEDDAEGEARDFDSQALPENYCIIEGRNSVVDFADMQAGEIAQNIESRRQRLFLLMEELRRLRVQQRVKTIGLDDDEVKETREFESVIPGFPVLTEDSVKDYRIYWGAAVGFLLLFGGLIAPMAEVKLGLGGTSYAEFIDSVHLPAQLAQVDPIVASFTGGAVGAISAFFVIEIQNVKEQRKKICMYCKGSGYLQCAECSTSNRPGRLIDPTSNTRCICPTCSGTAKVMCTSCLCTGMALATEHDPRIDPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAP0</accession>
    <name>A4SAP0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_4668</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422468.1">
        <property type="nucleotide sequence ID" value="XM_001422431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAP0"/>
    <dbReference type="STRING" id="436017.A4SAP0"/>
    <dbReference type="GeneID" id="5006526"/>
    <dbReference type="Gramene" id="ABP00785">
        <property type="protein sequence ID" value="ABP00785"/>
        <property type="gene ID" value="OSTLU_4668"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4668"/>
    <dbReference type="eggNOG" id="KOG1527">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_7_0_1"/>
    <dbReference type="OMA" id="EWTPQEY"/>
    <dbReference type="OrthoDB" id="508204at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902326">
        <property type="term" value="P:positive regulation of chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090352">
        <property type="term" value="P:regulation of nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900058">
        <property type="term" value="P:regulation of sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009416">
        <property type="term" value="P:response to light stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000001">
        <property type="entry name" value="Siroheme synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000001">
        <property type="entry name" value="Siroheme synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004790">
        <property type="entry name" value="PRK06136.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF3">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="26492" checksum="892C5D2D9295D9BA" modified="2007-05-15" version="1" fragment="single">VCLVGVGPGDPGLLTLRAYQLMQTADVVLYDRLVSNEILNLARAEARMVYVGKRAGYHTRTQEEIHELLAAFADAGATILRLKGGDPLVFGRGGEEFEFLREHNPNVRVEVVPGITAAAGVGSELGIPLTHRGVATSVRLLTGHLREGAGDPVDFAVTSADVETTLVVYMGLGTLPKLSEKLIASGFPADMPAVAIERGTTVDERRVFSSIEHLPEAAAACELVSPTLLIVGRTVTLSPHWPYAADESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAP6</accession>
    <name>A4SAP6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">APS reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">APR1</name>
        <name evidence="8" type="ORF">OSTLU_13445</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422646.1">
        <property type="nucleotide sequence ID" value="XM_001422609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAP6"/>
    <dbReference type="STRING" id="436017.A4SAP6"/>
    <dbReference type="GeneID" id="5006703"/>
    <dbReference type="Gramene" id="ABP00963">
        <property type="protein sequence ID" value="ABP00963"/>
        <property type="gene ID" value="OSTLU_13445"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13445"/>
    <dbReference type="eggNOG" id="KOG0189">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044089_4_0_1"/>
    <dbReference type="OMA" id="CMINGRT"/>
    <dbReference type="OrthoDB" id="7869097at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23945">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002537">
        <property type="entry name" value="PRK02090.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46482:SF9">
        <property type="entry name" value="5'-ADENYLYLSULFATE REDUCTASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46482">
        <property type="entry name" value="5'-ADENYLYLSULFATE REDUCTASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="278"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="415" mass="46129" checksum="58025EB8A0768D91" modified="2007-05-15" version="1">MRSARARGALRGPSARRAARRATTKARTTRAPSRATKADVDGMRDALERARATPLEIMDKALETHGDGLAIAFSGAEDVAVIQYAALTGRPYRVFSLDTGRLNPETYELFDKVEKHFDIKIEYCFPESEAVKALVNEKGMFSFYEDGHKECCGVRKVKPLRAKLATLTAWVTGQRKDQSPGTRNAVPACQIDPVFEGAAGGAGSLVKFNPLTDATSQEVWDFLRVMGTPVNALHERGYVSIGCAPCTRAVLPGQQEREGRWWWEDASDKECGLHSGNLTAEEKAKQDDREATEEDIFEHDSIRNLSRDDIAALKDEKTHGETTLAVLYAPWCPFCQRMVSGFETAAERLGPKGVKFAKFRADRDEKEWSQENLSMKSFPTLLLFPKGRSGYVKLGSERRDPDSLEIFIESITGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAS8</accession>
    <name>A4SAS8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">lycopene beta-cyclase</fullName>
            <ecNumber evidence="3">5.5.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_43800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carotenoid biosynthesis; beta-carotene biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carotenoid biosynthesis; beta-zeacarotene biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lycopene cyclase family.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.19" evidence="3"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422489.1">
        <property type="nucleotide sequence ID" value="XM_001422452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAS8"/>
    <dbReference type="STRING" id="436017.A4SAS8"/>
    <dbReference type="GeneID" id="5006547"/>
    <dbReference type="Gramene" id="ABP00806">
        <property type="protein sequence ID" value="ABP00806"/>
        <property type="gene ID" value="OSTLU_43800"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43800"/>
    <dbReference type="eggNOG" id="ENOG502QT2F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032956_1_0_1"/>
    <dbReference type="OMA" id="FVLMDFR"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045436">
        <property type="term" value="F:lycopene beta cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010108">
        <property type="entry name" value="Lycopene_cyclase_b/e"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01790">
        <property type="entry name" value="carotene-cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39757">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39757:SF5">
        <property type="entry name" value="OS02G0190600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05834">
        <property type="entry name" value="Lycopene_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="528" mass="58630" checksum="C0BECF3791F3B892" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAU9</accession>
    <name>A4SAU9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29386</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422666.1">
        <property type="nucleotide sequence ID" value="XM_001422629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAU9"/>
    <dbReference type="STRING" id="436017.A4SAU9"/>
    <dbReference type="GeneID" id="5006561"/>
    <dbReference type="Gramene" id="ABP00983">
        <property type="protein sequence ID" value="ABP00983"/>
        <property type="gene ID" value="OSTLU_29386"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29386"/>
    <dbReference type="eggNOG" id="KOG2908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042989_0_0_1"/>
    <dbReference type="OMA" id="SFEDYWE"/>
    <dbReference type="OrthoDB" id="1093at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054179">
        <property type="entry name" value="PSD13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035298">
        <property type="entry name" value="PSMD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22037">
        <property type="entry name" value="PSD13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="188"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="398" mass="43454" checksum="01822C1B6AB4092E" modified="2007-05-15" version="1">MPAAAPDAGTAYLDAAIDAARAIDDETRELLIEIGDLRTKKLWHELTLAIERAVAAPMNARVALLPGGLRGMYDGVVREAETRFNPLKTAHVAVAVSDALTGEEAVEFLTETSARLVAAHGDDAREPGVYVAAHVTLLRLVAGDLEYAKRAVTEGDKEALEALPAPDPSVSAAYHYVASRYYKVRENYAEFYKSGMLYLAYVSCEMLPAETRAALSVDLCLAALLGENVYNFAELLAHPIVESLNDGPFAWLMDVVKAFNEGDLHEYDQLCVKHAAALNAQPALVANERRLREKITILSLLQIIFKLPAEHREISLSDIAVKTKLTTDGVEYLLMKALSVHLIEGIIDQVESKVIVTWVQPRVLLRSQIAELAGRLDGWIEKVSAVESNLTDEIAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAX1</accession>
    <name>A4SAX1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422679.1">
        <property type="nucleotide sequence ID" value="XM_001422642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAX1"/>
    <dbReference type="GeneID" id="5006736"/>
    <dbReference type="Gramene" id="ABP00996">
        <property type="protein sequence ID" value="ABP00996"/>
        <property type="gene ID" value="OSTLU_29408"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29408"/>
    <dbReference type="HOGENOM" id="CLU_748838_0_0_1"/>
    <dbReference type="OMA" id="VECEQEF"/>
    <dbReference type="OrthoDB" id="10642925at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="370" mass="39539" checksum="1A6FA919A7356311" modified="2007-05-15" version="1">MLAPVAWLVFRGIKPTRAEREKYAMETRESETLAKRRVERDDEAAKLAKRLDEAKEAARAKAAKTMRATGPAGAATATATATATATNFKVEEKPKDVSAPAPEGAADERADASTRSDVGADVEDTAVISASTSSDETEATDAAVRVVSVNERSFETPESEAPVAPTPTVSHDVEPIVERHHADGEAYDVIAEHPKLVRAIHEANALVHKAHARRVESNQEFQDALRYREQVVHMASELGIPVAPLREVKETFKQSTYEAPLGPGAGEKAAEAAKSALAATKKFVDFAAPHVRSATTKAFDYSKQHATTAAGKLKQAHAKGDIRAPTLDEATDFAKSTSRRALGACVHAFDAITDQFAAVANKSAVKPQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB41</accession>
    <name>A4SB41_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_25867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422549.1">
        <property type="nucleotide sequence ID" value="XM_001422512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB41"/>
    <dbReference type="GeneID" id="5006769"/>
    <dbReference type="Gramene" id="ABP00866">
        <property type="protein sequence ID" value="ABP00866"/>
        <property type="gene ID" value="OSTLU_25867"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25867"/>
    <dbReference type="eggNOG" id="ENOG502S2NC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066761_0_0_1"/>
    <dbReference type="OrthoDB" id="497914at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="356" mass="38850" checksum="F0777E2F63E1DDCA" modified="2007-05-15" version="1">MRASPLATRASIDARAIGARRDAKARARRARDARAGATRDDDESWAFDPLALDARATRGATRGATRVASGACALVAVIACGASEDARAGGAAIDPFYAFSPVCPASDGVFRVGQRAAISLAGDENIENYRPLINDVLIRVRTELCVLESFVRETAVPFVREKGLGWVLPRRETSETYLAGVVFMLGANFILLGSTKVVAIMAIYHDLSLGLATRLFGSALGALGPTNEREKREKELNKVMDEQMNELKGVMSNWTIGKDDRARKTQEINDKYATKLEALRGSQEERSDRDDAVGLSKFRQVAGVVAVPLKVYGTVSSKGRQVLEVFDTFCSRYFVAFTVTYIIIKTAHYTVLKDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB59</accession>
    <name>A4SB59_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_9147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422719.1">
        <property type="nucleotide sequence ID" value="XM_001422682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB59"/>
    <dbReference type="SMR" id="A4SB59"/>
    <dbReference type="STRING" id="436017.A4SB59"/>
    <dbReference type="GeneID" id="5006618"/>
    <dbReference type="Gramene" id="ABP01036">
        <property type="protein sequence ID" value="ABP01036"/>
        <property type="gene ID" value="OSTLU_9147"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9147"/>
    <dbReference type="eggNOG" id="ENOG502QW9E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048788_5_2_1"/>
    <dbReference type="OMA" id="CTRSANK"/>
    <dbReference type="OrthoDB" id="545910at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="134" mass="15029" checksum="4B8AAC7FAC4528AB" modified="2007-05-15" version="1" fragment="single">WAGDLPYKYSGQTLDPVPVPEVLRRLQTAVEAKCGATFNHILLNRYRDGDDSMAFHADDEPELGKNACIAAVSVGHTRKFDVQVKSRAKKKTSIFLEHGSLMVMDGSLQHTHYHAVPKNRVPTNGKERINITFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBI0</accession>
    <name>A4SBI0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">VIC family transporter: potassium ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_43813</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the two pore domain potassium channel (TC 1.A.1.7) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422623.1">
        <property type="nucleotide sequence ID" value="XM_001422586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBI0"/>
    <dbReference type="GeneID" id="5006834"/>
    <dbReference type="Gramene" id="ABP00940">
        <property type="protein sequence ID" value="ABP00940"/>
        <property type="gene ID" value="OSTLU_43813"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43813"/>
    <dbReference type="eggNOG" id="KOG1420">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2613127_0_0_1"/>
    <dbReference type="OrthoDB" id="515205at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF291">
        <property type="entry name" value="IP11374P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="10">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP00940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="79" mass="8652" checksum="2FACEE22A446691B" modified="2007-05-15" version="1" fragment="single">HDVDGWSTFVDAVYFIAITVTTVGYGDISPQTDAGKIFMLFFIIVGIALATVVISKITDLIVDAKERSEVKAQEELDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQJ6</accession>
    <name>A4RQJ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_92063</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415401.1">
        <property type="nucleotide sequence ID" value="XM_001415364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQJ6"/>
    <dbReference type="STRING" id="436017.A4RQJ6"/>
    <dbReference type="GeneID" id="4999701"/>
    <dbReference type="Gramene" id="ABO93693">
        <property type="protein sequence ID" value="ABO93693"/>
        <property type="gene ID" value="OSTLU_92063"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92063"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_17_0_1"/>
    <dbReference type="OMA" id="EGQAMRI"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972">
        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="75"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="399"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="509" mass="54847" checksum="5A7178305DE9CB34" modified="2007-05-15" version="1">MPARADASARHRACERCRGEGATFALSRAQKKRRRLERDDGAATREAPEKRVECAACEGAGVVEGAATANGAAARVAIVGGGVGGAALALALTQRGARATVYERDERFEARKQGYGLTMQKYSGGAALRALGLALRGVGSDAHVSMDANGRVLGEYGHSARRRVGGEEDADQGARDGGAVAEAVSDEKRNVHLPRQKLRQSLLDALEPGVVRWGKRLERYEETEDGVTLRFDDGTSEEAGILVGADGIFSRVRAQKLGDDPLSYLGVLVVLGICRGVDAPLCRNKVFQVVDGENRMYAMPFTASPDGDGCIRPLDEQYEGEDEPGAMMWQLSFPVDEDRARALATDSEALWNEALRRCASWPDPVPRLLNQTRKEDMAGYPAYDRDMTPAEVLRGKVTSRVTLIGDAAHPMSPFKGQGANQALVDAVQLARCIVRSPQYMLPGQRRHGCVFPFESTHEALAAAERAMLARARGKVEKSRDAAKYLHSSAALAEGNCVRAHAAEAFASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQN3</accession>
    <name>A4RQN3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_10321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415764.1">
        <property type="nucleotide sequence ID" value="XM_001415727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQN3"/>
    <dbReference type="GeneID" id="4999921"/>
    <dbReference type="Gramene" id="ABO94056">
        <property type="protein sequence ID" value="ABO94056"/>
        <property type="gene ID" value="OSTLU_10321"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10321"/>
    <dbReference type="eggNOG" id="KOG4569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032957_5_0_1"/>
    <dbReference type="OMA" id="TITNWNC"/>
    <dbReference type="OrthoDB" id="495609at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF25">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="43"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="234" mass="25918" checksum="1DE14130947CE94D" modified="2007-05-15" version="1" fragment="single">VENWTCAYCASSKTTLADVGVFEHERKRVRAYAGYDGTLKRGVVAFRGTEPSSLYNWVENLDAAHSTLPTAKAKDGVGRVHSGFQDAYESVRKGLISHMIKLRTNYDGMWRHFEVEITGHSLGGALSTLLAVELEALGFRIARVTTFGSPRVGDWRFADYYDEKLGDRTHRFTHAHDAVPSLPPRLLGYHHVATEVFQNAEGEYVVGDGSGEDPNGSDSEWTHASLSDHLTYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQT5</accession>
    <name>A4RQT5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_7447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C85 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415790.1">
        <property type="nucleotide sequence ID" value="XM_001415753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQT5"/>
    <dbReference type="STRING" id="436017.A4RQT5"/>
    <dbReference type="GeneID" id="4999779"/>
    <dbReference type="KEGG" id="olu:OSTLU_7447"/>
    <dbReference type="eggNOG" id="KOG2605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044001_2_2_1"/>
    <dbReference type="OrthoDB" id="498216at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22751">
        <property type="entry name" value="OTU_plant_OTU9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF11">
        <property type="entry name" value="OTU DOMAIN-CONTAINING PROTEIN DDB_G0284757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="10"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO94082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="15581" checksum="8CF9D84253D0457E" modified="2007-05-15" version="1" fragment="single">LDARLGRLGMTRVPMVGDGNCQFRALAANALRDQERHAEIRELATTRVEERREDFEIYFDGPRALDKWLREMKRDRTWGDELTLRAACDALGQKIHCVQSTQSNWYLLYEPEELKSKRMCFISYVSPVHYDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQY6</accession>
    <name>A4RQY6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3 13">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_12103</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Plastid</location>
            <location evidence="13">Chloroplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Plastid</location>
        </subcellularLocation>
        <text evidence="13">And non-photosynthetic plastids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3 13"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415472.1">
        <property type="nucleotide sequence ID" value="XM_001415435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQY6"/>
    <dbReference type="STRING" id="436017.A4RQY6"/>
    <dbReference type="GeneID" id="4999626"/>
    <dbReference type="Gramene" id="ABO93764">
        <property type="protein sequence ID" value="ABO93764"/>
        <property type="gene ID" value="OSTLU_12103"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12103"/>
    <dbReference type="eggNOG" id="KOG1200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="OMA" id="CQKHMVD"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05333">
        <property type="entry name" value="BKR_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000037">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] reductase FabG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009466">
        <property type="entry name" value="PRK12826.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 12 13" id="KW-0521">NADP</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="14">
        <location>
            <begin position="29"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="35"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="180"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO93764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="28137" checksum="3464B5EAAE88FEF1" modified="2007-05-15" version="1">MSTVAARALASRSSVAKFASRAAKHASGPVCVVTGASRGIGAAIALALGQQGARVVVNYAASEGPANEVCEKIKAAGGDAIAVKANVAVPEDVDALFKATMDKFGEVNVLVNNAGITRDTLMMRMKLQQWQEVIDLNLTGVFLCTQAATKAMGKKKPVSGRIINITSVVGVTGNAGQANYSAAKAGVIGLTKTVAREYAGRNIQCNAIAPGFIASDMTAVLGEELEKKILTTIPAGRYGQPEEIAGLVKFLAMDPAAAYITGQTLHVDGGMVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR49</accession>
    <name>A4RR49_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_23897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415510.1">
        <property type="nucleotide sequence ID" value="XM_001415473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR49"/>
    <dbReference type="GeneID" id="4999569"/>
    <dbReference type="Gramene" id="ABO93802">
        <property type="protein sequence ID" value="ABO93802"/>
        <property type="gene ID" value="OSTLU_23897"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_23897"/>
    <dbReference type="HOGENOM" id="CLU_856315_0_0_1"/>
    <dbReference type="OrthoDB" id="10670465at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="34459" checksum="EA1CFDD95A536099" modified="2007-05-15" version="1">MNDDVAGVATNDTRHQRPPKIKLRLNIPARDDDDEKGRAGTTRKRTTTTTTTTTTTSRENSMSMSMGASMSLGEHGDEHGDEATQGMSFLSPPTGRQKRHTHSPATTPMSVGTSPRISSKRPRMSNDWIEDEVHPSMVMGTPGSGGTAAKRLTSEIMASNLSQLLSVSPMSTNNDGGTACAVDESWTSSSAPMSFGETVKSSTSLLKRTLSGTYGDTTGMLMLTAPQLAKSPTESMMVSHHGGGGLPPSSPSDPSPIHDLRKAALMRSRLLNVSSALPPRATPSSTRGNHLQRGFVHERPPIHSLGVGTVDVGDETESGERNVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR51</accession>
    <name>A4RR51_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415512.1">
        <property type="nucleotide sequence ID" value="XM_001415475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR51"/>
    <dbReference type="GeneID" id="4999873"/>
    <dbReference type="Gramene" id="ABO93804">
        <property type="protein sequence ID" value="ABO93804"/>
        <property type="gene ID" value="OSTLU_28892"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28892"/>
    <dbReference type="HOGENOM" id="CLU_1201537_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO93804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="231" mass="25069" checksum="C369C0C0F50739BA" modified="2007-05-15" version="1">MCTNGDAMTTNDVIAIQRRRSDDDAPKTPPKTPSSSDNLLHVLAGWTTITPAPLGDDAEKEDQKDDDDDDDDALSRCTTTNRRLDRDFGRHAEPIDDGALTTPTAPPPPTEPFPAKGRALLNTLLPNLKTSPSESPSPSSSSLARIEALLQALVKRVETVESKLDEVLSRCDERQKHDDNALDDACDDDDDNHFHTPKSEPRSISIASSPCLVRASPSPSIVNAFAELYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR54</accession>
    <name>A4RR54_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NADPH-dependent FMN and FAD-containing oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_40283</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415838.1">
        <property type="nucleotide sequence ID" value="XM_001415801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR54"/>
    <dbReference type="STRING" id="436017.A4RR54"/>
    <dbReference type="GeneID" id="4999837"/>
    <dbReference type="Gramene" id="ABO94130">
        <property type="protein sequence ID" value="ABO94130"/>
        <property type="gene ID" value="OSTLU_40283"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40283"/>
    <dbReference type="eggNOG" id="KOG1159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_17_6_1"/>
    <dbReference type="OMA" id="DIMSIPR"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000015">
        <property type="entry name" value="NADPH-dependent diflavin oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000032">
        <property type="entry name" value="NADPH-dependent diflavin oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF10">
        <property type="entry name" value="NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="10">
        <location>
            <begin position="23"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="232"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="69783" checksum="19969C149E3401D6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR70</accession>
    <name>A4RR70_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Iron-sulfur cluster assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the NifU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415848.1">
        <property type="nucleotide sequence ID" value="XM_001415811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR70"/>
    <dbReference type="STRING" id="436017.A4RR70"/>
    <dbReference type="GeneID" id="4999781"/>
    <dbReference type="Gramene" id="ABO94140">
        <property type="protein sequence ID" value="ABO94140"/>
        <property type="gene ID" value="OSTLU_28911"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28911"/>
    <dbReference type="eggNOG" id="KOG3361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079283_1_1_1"/>
    <dbReference type="OMA" id="YMTERVR"/>
    <dbReference type="OrthoDB" id="1925777at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1010.10:FF:000008">
        <property type="entry name" value="Iron-sulfur cluster assembly enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISCU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU N-terminal" evidence="5">
        <location>
            <begin position="29"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="158" mass="16962" checksum="52DA78971B6CA4B6" modified="2007-05-15" version="1">MLRRAIERTARRGTTSAKSVACSRVFERAYDKKVVDHYENPRNVGSFDKSDLNVGTGVVGAPACGDVMKLQIKVDDEGNIVDSCFKTFGCGSAIASSSVATEWIKGTHVDEAVTIKNQDIAKHLNLPPVKLHCSMLAEDAIRSAVADIKAKRAAAKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRM4</accession>
    <name>A4RRM4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29069</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415927.1">
        <property type="nucleotide sequence ID" value="XM_001415890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRM4"/>
    <dbReference type="GeneID" id="4999389"/>
    <dbReference type="Gramene" id="ABO94219">
        <property type="protein sequence ID" value="ABO94219"/>
        <property type="gene ID" value="OSTLU_29069"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29069"/>
    <dbReference type="eggNOG" id="KOG0463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012821_2_0_1"/>
    <dbReference type="OMA" id="FRFIQRP"/>
    <dbReference type="OrthoDB" id="248233at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04165">
        <property type="entry name" value="GTPBP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035531">
        <property type="entry name" value="GTPBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="139"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="594" mass="65028" checksum="BF89511E566212CA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRS4</accession>
    <name>A4RRS4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lhcp1</name>
        <name evidence="8" type="ORF">OSTLU_29120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415950.1">
        <property type="nucleotide sequence ID" value="XM_001415913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRS4"/>
    <dbReference type="STRING" id="436017.A4RRS4"/>
    <dbReference type="GeneID" id="4999380"/>
    <dbReference type="Gramene" id="ABO94242">
        <property type="protein sequence ID" value="ABO94242"/>
        <property type="gene ID" value="OSTLU_29120"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29120"/>
    <dbReference type="HOGENOM" id="CLU_1201257_0_0_1"/>
    <dbReference type="OMA" id="HVADPIH"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 7" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="2 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4 7" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="254" mass="26997" checksum="862A03DC3E85B53F" modified="2007-05-15" version="1">MLTSTFTGVRVAAAPKRATSRKIDTAVVARRTKASAPAKKSAFKAGQFGSLAPPDLYPEFGTYPGGGESPIIPFGDEKNAEREIIHGRWAMLGVTGAWAAENGTGIPWFTAGTLCTPDDCTAVADKFPGAVAPLAPAGSGYPNFWAVLAIEIFLVGSAESYRTGIFENPFPELTQGDVTPGGRFDPLGFAEAGDLEELKIKELKHSRLSMFAWLGCIFQALATQEGPIANWQSHVADPIHSNVLTNAAKGFSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS20</accession>
    <name>A4RS20_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_29215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat MORG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415663.1">
        <property type="nucleotide sequence ID" value="XM_001415626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS20"/>
    <dbReference type="STRING" id="436017.A4RS20"/>
    <dbReference type="GeneID" id="4999911"/>
    <dbReference type="Gramene" id="ABO93955">
        <property type="protein sequence ID" value="ABO93955"/>
        <property type="gene ID" value="OSTLU_29215"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29215"/>
    <dbReference type="eggNOG" id="KOG0316">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_1_1"/>
    <dbReference type="OMA" id="MCWDIRT"/>
    <dbReference type="OrthoDB" id="71437at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902895">
        <property type="term" value="P:positive regulation of miRNA transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051980">
        <property type="entry name" value="WD_repeat_MORG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842:SF3">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING PROTEIN 83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="55"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="245"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO93955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="317" mass="33280" checksum="1C1C100A854E141B" modified="2007-05-15" version="1">MSLPTHRARDLAGAHDGAVLAARFSRDAAHCVTCGRDRAFALWNARKGTLLRVYRGGHAREVRDASCARDGARIATCGGDRGVFLWDVATGASVRRWSGHEGEGGANATALCGPGDALCASAGYDASVRLWDCRASGARAMQVMHARTGVAFGDSVTSLSVDEDGAKIAAGCVDGCARTIDLRNGKCHVDSVGAPVTSVCFSHDKQCLIVGCLTSRVALLDCASGNAMATYRGHVAERAKTECRFSNTDAHVVASSEDGRVVFWDLVTGDVVRELQAHDRSTVVCSIDYAPEGAEPAMATCAADGTARYWTAPPTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSK7</accession>
    <name>A4RSK7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ara54-like RING finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Ara54</name>
        <name evidence="14" type="ORF">OSTLU_119676</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RBR family. RNF14 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416228.1">
        <property type="nucleotide sequence ID" value="XM_001416191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSK7"/>
    <dbReference type="STRING" id="436017.A4RSK7"/>
    <dbReference type="GeneID" id="5000262"/>
    <dbReference type="Gramene" id="ABO94521">
        <property type="protein sequence ID" value="ABO94521"/>
        <property type="gene ID" value="OSTLU_119676"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119676"/>
    <dbReference type="eggNOG" id="KOG1814">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021364_1_0_1"/>
    <dbReference type="OMA" id="SVKWLEP"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20341">
        <property type="entry name" value="BRcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23820">
        <property type="entry name" value="RWD_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="12">
        <location>
            <begin position="36"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="233"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="237"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="552" mass="61596" checksum="97C117422C636336" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT09</accession>
    <name>A4RT09_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">smo1</name>
        <name evidence="1" type="ORF">OSTLU_119507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416152.1">
        <property type="nucleotide sequence ID" value="XM_001416115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT09"/>
    <dbReference type="GeneID" id="5000500"/>
    <dbReference type="Gramene" id="ABO94445">
        <property type="protein sequence ID" value="ABO94445"/>
        <property type="gene ID" value="OSTLU_119507"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119507"/>
    <dbReference type="HOGENOM" id="CLU_3369284_0_0_1"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="35" mass="4124" checksum="20F725D58E78C60B" modified="2007-05-15" version="1">MICIGGVCIPYAAMIPMLINFFRYLRTLFWTRVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT41</accession>
    <name>A4RT41_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TraS3</name>
        <name evidence="4" type="ORF">OSTLU_119479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416139.1">
        <property type="nucleotide sequence ID" value="XM_001416102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT41"/>
    <dbReference type="GeneID" id="5000474"/>
    <dbReference type="Gramene" id="ABO94432">
        <property type="protein sequence ID" value="ABO94432"/>
        <property type="gene ID" value="OSTLU_119479"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119479"/>
    <dbReference type="HOGENOM" id="CLU_327997_0_0_1"/>
    <dbReference type="OMA" id="EANIECT"/>
    <dbReference type="OrthoDB" id="10043687at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="214"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="597"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="599"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="870" mass="97645" checksum="6CFC5667F9F96976" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT67</accession>
    <name>A4RT67_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416365.1">
        <property type="nucleotide sequence ID" value="XM_001416328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT67"/>
    <dbReference type="GeneID" id="5000246"/>
    <dbReference type="Gramene" id="ABO94658">
        <property type="protein sequence ID" value="ABO94658"/>
        <property type="gene ID" value="OSTLU_92293"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92293"/>
    <dbReference type="HOGENOM" id="CLU_919325_0_0_1"/>
    <dbReference type="OMA" id="YQETSCA"/>
    <dbReference type="OrthoDB" id="10551982at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050210">
        <property type="entry name" value="tRNA_Adenine-N(6)_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47739">
        <property type="entry name" value="TRNA1(VAL) (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47739:SF1">
        <property type="entry name" value="TRNA1(VAL) (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase small" evidence="1">
        <location>
            <begin position="76"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="311" mass="33365" checksum="C029840C9971ECB8" modified="2007-05-15" version="1">MRAALASPRAARPATTIVRALSTAPRAPRVADGETLDVLGASKLRVVQSKVGYRTGVDALALAWFARRSRGDVESFADRACDLGAGSSGAVGLAYALSGARPARATFVEAQRDSCERLRRSVETNARASDAFDVVPGDVVEDARALLDDRKMRRAFDVVLTNPPFFEATRGTPPKNKEKKGARFGILEDGGAATIHDFIGFAKEALREDGEFFVVYPSLGRARLLAAMVAAFGDDAVRATDVFDHEGASRPSLVFARATLRGYSGDAVETSCALYQETSCALYQEARVGEGKRAYVDSFEMFLQRVAQAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTA0</accession>
    <name>A4RTA0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_36485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416109.1">
        <property type="nucleotide sequence ID" value="XM_001416072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTA0"/>
    <dbReference type="STRING" id="436017.A4RTA0"/>
    <dbReference type="GeneID" id="5000379"/>
    <dbReference type="Gramene" id="ABO94401">
        <property type="protein sequence ID" value="ABO94401"/>
        <property type="gene ID" value="OSTLU_36485"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36485"/>
    <dbReference type="eggNOG" id="KOG1252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_1_0_1"/>
    <dbReference type="OMA" id="VFDDDWM"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000003">
        <property type="entry name" value="Cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="4">
        <location>
            <begin position="23"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="334" mass="35821" checksum="4696CECFAF2A4704" modified="2007-05-15" version="1" fragment="single">MTDPKHWRSTHARIANGPVVPQQLIGGTPMIDLSEFSANPKVKIYGKCEYLNPSGSIKDRIAQEILARALETGELKAGMTVVAATSGNTGAAIAMACAIRGFPYIVITNQKTSKEKIDAMRAYGGEVIVAPSGVPADHPDHYQNIEATMCAKNPKFYGVNQYDNPYNADAYEKTLGPEIWSQTEGAVTHFVAGGSTGGTITGTGRYLKSVDPTIKIVLADPKGSVLWDYFVNDIPEEELVAKSWEVEGVGKDSIPGVLDTEYIDGAVMGDDSSSFRMVRTVAESSGVLLGGSSGLNLHAARVLSSHIKEGTIVTVLCDSGVKYLSKIYNDEWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTJ1</accession>
    <name>A4RTJ1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL15</name>
        <name evidence="5" type="ORF">OSTLU_14085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416062.1">
        <property type="nucleotide sequence ID" value="XM_001416025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTJ1"/>
    <dbReference type="STRING" id="436017.A4RTJ1"/>
    <dbReference type="GeneID" id="5000296"/>
    <dbReference type="Gramene" id="ABO94354">
        <property type="protein sequence ID" value="ABO94354"/>
        <property type="gene ID" value="OSTLU_14085"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14085"/>
    <dbReference type="eggNOG" id="KOG1678">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080796_0_0_1"/>
    <dbReference type="OMA" id="YIRDAWK"/>
    <dbReference type="OrthoDB" id="10255148at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="204" mass="24447" checksum="45A8C9383843CE79" modified="2007-05-15" version="1">MGAYKYVEELWKKKQSDVMRFLQRIRVWEYRQLPSICRVTRPTRPDKARRLGYKAKQGFCIYRARVRRGGRKRPVAKGQVYGKPVHCGITKLKFARNLRSVAEERAARRCGALRVLNSYWLNQDSVYKYYEVIMVDPMHKCVRNDPRINWICNPTHKHREMRGLTSAGRKYRGLHGKGHNFTKSRPSKRATWRNNNRLSYRRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTM9</accession>
    <name>A4RTM9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416044.1">
        <property type="nucleotide sequence ID" value="XM_001416007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTM9"/>
    <dbReference type="GeneID" id="5000206"/>
    <dbReference type="Gramene" id="ABO94336">
        <property type="protein sequence ID" value="ABO94336"/>
        <property type="gene ID" value="OSTLU_29820"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29820"/>
    <dbReference type="eggNOG" id="ENOG502T27B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2546700_0_0_1"/>
    <dbReference type="OrthoDB" id="543322at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="83" mass="8172" checksum="E28CCF74C825D1B4" modified="2007-05-15" version="1">MAAKSALAITIPSQASSGGLGRESGMAFSSTQASSSGYTLEGTKKTGMSVKTKRGTLASVRAAAEAEVNAPKAAAAKPAKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU68</accession>
    <name>A4RU68_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1995 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_86670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416906.1">
        <property type="nucleotide sequence ID" value="XM_001416869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU68"/>
    <dbReference type="GeneID" id="5000633"/>
    <dbReference type="Gramene" id="ABO95199">
        <property type="protein sequence ID" value="ABO95199"/>
        <property type="gene ID" value="OSTLU_86670"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86670"/>
    <dbReference type="eggNOG" id="ENOG502S1TJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071171_0_0_1"/>
    <dbReference type="OMA" id="PGDWQVF"/>
    <dbReference type="OrthoDB" id="8026949at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053021">
        <property type="entry name" value="Chloroplast_ADK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (DUF1995)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509:SF4">
        <property type="entry name" value="DUF1995 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1995" evidence="1">
        <location>
            <begin position="23"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="267" mass="29592" checksum="651AD47464ADC888" modified="2007-05-15" version="1">MNKTRTRAARAARTVVSALPSLPLNTKEQIEQAAGAIEAALRDGKTTQAIELNLPLIGATDLDDWPGGIRQQYGALAPMVSEVLRLINAGAEGTCQQRVIDDADAVAALTLGSDVVVSFPTAEVLDDLRAIENKNDFRLKIIANPQWNTKGAIIGDFGFGPWKRRAEEFVGKFEQTYYLKEQRIQGEIVRTLKVYPNKWQVFALAPNENNKIVAEALGEFDERPLYDQLKKLLESREGSIAAMNWVERAKREATFNAKSLQAPPNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUD1</accession>
    <name>A4RUD1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-4-methyl-2-oxoglutarate aldolase</fullName>
            <shortName evidence="9">HMG aldolase</shortName>
            <ecNumber evidence="9">4.1.1.112</ecNumber>
            <ecNumber evidence="9">4.1.3.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Oxaloacetate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_8571</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 9">Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate</text>
            <dbReference type="Rhea" id="RHEA:22748"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:58276"/>
            <dbReference type="EC" id="4.1.3.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>oxaloacetate + H(+) = pyruvate + CO2</text>
            <dbReference type="Rhea" id="RHEA:15641"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="4.1.1.112"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class II aldolase/RraA-like family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.112" evidence="9"/>
    <dbReference type="EC" id="4.1.3.17" evidence="9"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416939.1">
        <property type="nucleotide sequence ID" value="XM_001416902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUD1"/>
    <dbReference type="STRING" id="436017.A4RUD1"/>
    <dbReference type="GeneID" id="5000881"/>
    <dbReference type="Gramene" id="ABO95232">
        <property type="protein sequence ID" value="ABO95232"/>
        <property type="gene ID" value="OSTLU_8571"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8571"/>
    <dbReference type="eggNOG" id="ENOG502S32I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072626_4_0_1"/>
    <dbReference type="OMA" id="RIAHGEW"/>
    <dbReference type="OrthoDB" id="497852at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047443">
        <property type="term" value="F:4-hydroxy-4-methyl-2-oxoglutarate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008428">
        <property type="term" value="F:ribonuclease inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051252">
        <property type="term" value="P:regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010203">
        <property type="entry name" value="RraA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01935">
        <property type="entry name" value="NOT-MenG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006875">
        <property type="entry name" value="PRK09372.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254:SF4">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="53"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605493-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="136" mass="14499" checksum="90C06B910677AEF1" modified="2007-05-15" version="1" fragment="single">FKDFGGRRRFHGEVTTVSCYENNPLVRAALEEPGRGRVLVVDGGASTRCALLGDNLAEMAATNGWSGIIVNGCVRDSEDIARFDVGVKAIGTHPLKSSKRDPGRRDARVSFAGVDFEPGSYVYADADGVVVAAKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUI8</accession>
    <name>A4RUI8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_3732</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ESV1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416678.1">
        <property type="nucleotide sequence ID" value="XM_001416641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUI8"/>
    <dbReference type="STRING" id="436017.A4RUI8"/>
    <dbReference type="GeneID" id="5001015"/>
    <dbReference type="Gramene" id="ABO94971">
        <property type="protein sequence ID" value="ABO94971"/>
        <property type="gene ID" value="OSTLU_3732"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3732"/>
    <dbReference type="eggNOG" id="ENOG502QSD3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040240_0_0_1"/>
    <dbReference type="OMA" id="KGDEWHE"/>
    <dbReference type="OrthoDB" id="495716at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043036">
        <property type="term" value="C:starch grain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000904">
        <property type="term" value="P:regulation of starch metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005982">
        <property type="term" value="P:starch metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052495">
        <property type="entry name" value="Alpha-glucan_binding_chloro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34113">
        <property type="entry name" value="INACTIVE PURPLE ACID PHOSPHATASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34113:SF2">
        <property type="entry name" value="PROTEIN LIKE EARLY STARVATION, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="285" mass="32374" checksum="4C6A91D9F204B694" modified="2007-05-15" version="1" fragment="single">GTLENGSRWWRESGEEELEGGKLCRWTLVRGASADGSVEWEEKWWETSDAFNYRELGAIKSGRDAKGNVWQESWREQVTHDTTTGFSNASKHIMREANKWGAQADGAEWHEVWDENYWGDGQVKRTCTKKGAIANGATPDDGHGNRWTHKWGEEWDGHGGCVKWTDSFADRDQSEDGGSGRAWGEKWEERWGGYAHNGSAGNRNGSTWDDRDGHKFEKTWGEEHWHDGRVHKWGATTDGSDGWDTWEDSAGWWERAPSFGWDEAVSHSPQLLNVPLRPRGTGVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUW4</accession>
    <name>A4RUW4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAC-A/B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_12381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May promote appropriate targeting of ribosome-nascent polypeptide complexes.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416740.1">
        <property type="nucleotide sequence ID" value="XM_001416703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUW4"/>
    <dbReference type="STRING" id="436017.A4RUW4"/>
    <dbReference type="GeneID" id="5000916"/>
    <dbReference type="Gramene" id="ABO95033">
        <property type="protein sequence ID" value="ABO95033"/>
        <property type="gene ID" value="OSTLU_12381"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_12381"/>
    <dbReference type="eggNOG" id="KOG2239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057806_2_1_1"/>
    <dbReference type="OMA" id="ALMELTI"/>
    <dbReference type="OrthoDB" id="3169036at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000002">
        <property type="entry name" value="Nascent polypeptide-associated complex (NAC), alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000006">
        <property type="entry name" value="Putative nascent polypeptide-associated complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAC-A/B" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="12883" checksum="1AB2C46087CAA8CF" modified="2007-05-15" version="1">MQKLGLEQLDDVQRVTFRKGKQAMFVINSPDVFHSPGSDSYVIFGEAKTEDLAAQAAQLKNAFKAEAPAAGAAMPTLEETGVEAKDIELVMTQANVSRAKAVTALKANPGDIVSAIMDLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUZ9</accession>
    <name>A4RUZ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_34459</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DExH box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416755.1">
        <property type="nucleotide sequence ID" value="XM_001416718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUZ9"/>
    <dbReference type="STRING" id="436017.A4RUZ9"/>
    <dbReference type="GeneID" id="5000647"/>
    <dbReference type="Gramene" id="ABO95048">
        <property type="protein sequence ID" value="ABO95048"/>
        <property type="gene ID" value="OSTLU_34459"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34459"/>
    <dbReference type="eggNOG" id="KOG0920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_1_4_1"/>
    <dbReference type="OMA" id="PNTRMQL"/>
    <dbReference type="OrthoDB" id="5600252at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000526">
        <property type="entry name" value="DExH-box ATP-dependent RNA helicase DExH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000002">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF237">
        <property type="entry name" value="ATP-DEPENDENT DNA_RNA HELICASE DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="133"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="393"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="936" mass="104112" checksum="7B2E6E07CF1E5D8B" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV51</accession>
    <name>A4RV51_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416781.1">
        <property type="nucleotide sequence ID" value="XM_001416744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV51"/>
    <dbReference type="STRING" id="436017.A4RV51"/>
    <dbReference type="GeneID" id="5000987"/>
    <dbReference type="Gramene" id="ABO95074">
        <property type="protein sequence ID" value="ABO95074"/>
        <property type="gene ID" value="OSTLU_30849"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30849"/>
    <dbReference type="HOGENOM" id="CLU_1311966_0_0_1"/>
    <dbReference type="OMA" id="WSIVHEG"/>
    <dbReference type="OrthoDB" id="514051at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47426">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASES (NAT) SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47426:SF3">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="210" mass="22749" checksum="B86BE688BCED600E" modified="2007-05-15" version="1">MRQAGVRSLRTFAVLARTDASGRRAGFEESSTTGETPADAEALRRWSIVHEGADANADTSVAESHLAVVGTLDVHLGAKLPGEILVGRRPFADASADASADAANDQYGFDPLAVVDPPRAYVFNVCVAPEFRGRGVAEAMLRVSYEYLASRTRAAVVYIHVERDNVSARRAYEKALFSIESEETPEQSASAAHEPRILLYREILRASPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVJ0</accession>
    <name>A4RVJ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="8">2.7.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_30992</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.21" evidence="8"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417429.1">
        <property type="nucleotide sequence ID" value="XM_001417392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVJ0"/>
    <dbReference type="STRING" id="436017.A4RVJ0"/>
    <dbReference type="GeneID" id="5001374"/>
    <dbReference type="Gramene" id="ABO95722">
        <property type="protein sequence ID" value="ABO95722"/>
        <property type="gene ID" value="OSTLU_30992"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30992"/>
    <dbReference type="eggNOG" id="KOG0575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_46_1_1"/>
    <dbReference type="OMA" id="NMPESDH"/>
    <dbReference type="OrthoDB" id="408964at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
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        <source>
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        <source>
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        <source>
            <dbReference type="EMBL" id="ABO95722.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
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</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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            <strain evidence="2 3">CCE9901</strain>
        </source>
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    </dbReference>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
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</entry>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ABO95821"/>
        <property type="gene ID" value="OSTLU_31224"/>
    </dbReference>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_398175_0_0_1"/>
    <dbReference type="OMA" id="PANAYML"/>
    <dbReference type="OrthoDB" id="10577563at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Nopp140-like"/>
    </dbReference>
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        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="692" mass="74590" checksum="3E107992DE22805D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWG2</accession>
    <name>A4RWG2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_49447</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of a prohibitin multimeric complex in mitochondrial membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the prohibitin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417571.1">
        <property type="nucleotide sequence ID" value="XM_001417534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWG2"/>
    <dbReference type="STRING" id="436017.A4RWG2"/>
    <dbReference type="GeneID" id="5001464"/>
    <dbReference type="Gramene" id="ABO95864">
        <property type="protein sequence ID" value="ABO95864"/>
        <property type="gene ID" value="OSTLU_49447"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49447"/>
    <dbReference type="eggNOG" id="KOG3083">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047969_0_2_1"/>
    <dbReference type="OMA" id="VPFIQNP"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="28"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="275" mass="29876" checksum="C84772AD13A75D7E" modified="2007-05-15" version="1">MSAAANALTNLARAAVTIGVGASVASQAIYDVDGGERAVMFDRFRGVLPVTSGEGTHFVVPFIQNPTIYDVRTRAKSLTSVTGTKDLQQVNLTLRVLCRPDVDKLPKIHQELGQDYDDRVLPSIGNEVLKATVAQFNADQLLTQRQLVSQRVSEALRLRAADFGIILDDVALTHLSFSSEYTKAIEAKQVSQQEAERAAYVVKRSEQEREAAIIRAEGESESARLISQATKAAGPALVELRRIEASKEIAQTLARSRNVMYLPGGGANMLLGLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWI8</accession>
    <name>A4RWI8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_36947</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417586.1">
        <property type="nucleotide sequence ID" value="XM_001417549.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RWI8"/>
    <dbReference type="GeneID" id="5001422"/>
    <dbReference type="Gramene" id="ABO95879">
        <property type="protein sequence ID" value="ABO95879"/>
        <property type="gene ID" value="OSTLU_36947"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36947"/>
    <dbReference type="eggNOG" id="KOG0929">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000691_1_2_1"/>
    <dbReference type="OMA" id="EVMCAYI"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000003">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.20:FF:000002">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="8">
        <location>
            <begin position="527"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="492"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="510"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO95879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1447" mass="159110" checksum="468F18DB7096182C" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWJ5</accession>
    <name>A4RWJ5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31358</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417589.1">
        <property type="nucleotide sequence ID" value="XM_001417552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWJ5"/>
    <dbReference type="GeneID" id="5001562"/>
    <dbReference type="Gramene" id="ABO95882">
        <property type="protein sequence ID" value="ABO95882"/>
        <property type="gene ID" value="OSTLU_31358"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31358"/>
    <dbReference type="eggNOG" id="ENOG502RZB5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1484379_0_0_1"/>
    <dbReference type="OMA" id="RSFFWEC"/>
    <dbReference type="OrthoDB" id="337581at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097196">
        <property type="term" value="C:Shu complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28498">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28498:SF1">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="105"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="182" mass="20064" checksum="054407EE304C0D55" modified="2007-05-15" version="1">MGAAPARRRATSTSEAEDDSNPKRWRDASNDARHRGAAIAEAAFDALARRARVARDANRAIDVPDDALEALAWLYGAKHLQKALEVMQAGRVRRVVAERSGRSMYAVHGSGAHERAPYLCFPAHFCSCRSFFWECVNRGEALACKHQLAAKLASVLRCAKTTTVDDVLLGNMMMKSFEDDPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWN1</accession>
    <name>A4RWN1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="12">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="12">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_37270</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="12"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417607.1">
        <property type="nucleotide sequence ID" value="XM_001417570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWN1"/>
    <dbReference type="STRING" id="436017.A4RWN1"/>
    <dbReference type="GeneID" id="5001269"/>
    <dbReference type="Gramene" id="ABO95900">
        <property type="protein sequence ID" value="ABO95900"/>
        <property type="gene ID" value="OSTLU_37270"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37270"/>
    <dbReference type="eggNOG" id="KOG0188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_5_0_1"/>
    <dbReference type="OMA" id="NCLEIWN"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070143">
        <property type="term" value="P:mitochondrial alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000011">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 12" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="13">
        <location>
            <begin position="28"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="622"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="737"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="741"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="967" mass="104242" checksum="7833872A588B439C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX74</accession>
    <name>A4RX74_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">hydroxymethylbilane synthase</fullName>
            <ecNumber evidence="5">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Hydroxymethylbilane synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_31592</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="5"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417948.1">
        <property type="nucleotide sequence ID" value="XM_001417911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX74"/>
    <dbReference type="STRING" id="436017.A4RX74"/>
    <dbReference type="GeneID" id="5001907"/>
    <dbReference type="Gramene" id="ABO96241">
        <property type="protein sequence ID" value="ABO96241"/>
        <property type="gene ID" value="OSTLU_31592"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31592"/>
    <dbReference type="eggNOG" id="KOG2892">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019704_1_2_1"/>
    <dbReference type="OMA" id="LWQANHI"/>
    <dbReference type="OrthoDB" id="564646at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900865">
        <property type="term" value="P:chloroplast RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13648">
        <property type="entry name" value="PBP2_PBGD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000004">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000101">
        <property type="entry name" value="Porphobilinogen deaminase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="entry name" value="Porphobilinogen deaminase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557:SF0">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobilinogen deaminase N-terminal" evidence="10">
        <location>
            <begin position="12"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobilinogen deaminase C-terminal" evidence="11">
        <location>
            <begin position="237"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO96241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="35140" checksum="7C87B9F46D1CDF04" modified="2007-05-15" version="1">MVVRAAVDAPIVKIGTRGSPLALAQAYMTRDLLKENFPELAEDGALEICIIKTTGDKVLDQPLADIGGKGLFTRELDDALLDGRIDIAVHSMKDVPTYLPEGMVLPCMLPREDVRDAFLCLKYDSLSQLPEGAVVGTASLRRQSQLLYKFPTLKCVNFRGNVQSRIRKLKEEVVDCTLLAIAGLKRMDLAQHAKVIIPTEEMLPAVAQGAIGITCRAGDDKQLAFLAKLNHEDTRMAVEGERSFLAALDGSCRTPIAAHCHLVDGKMQFRGLIASLDGKQVLETTREGAWDAASLLDAGKDAGAELKGKAPADFFANLIENGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXK2</accession>
    <name>A4RXK2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_38525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417767.1">
        <property type="nucleotide sequence ID" value="XM_001417730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXK2"/>
    <dbReference type="STRING" id="436017.A4RXK2"/>
    <dbReference type="GeneID" id="5001807"/>
    <dbReference type="Gramene" id="ABO96060">
        <property type="protein sequence ID" value="ABO96060"/>
        <property type="gene ID" value="OSTLU_38525"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38525"/>
    <dbReference type="eggNOG" id="KOG0946">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006318_3_0_1"/>
    <dbReference type="OMA" id="GQETFCN"/>
    <dbReference type="OrthoDB" id="198977at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048211">
        <property type="term" value="P:Golgi vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006955">
        <property type="entry name" value="Uso1_p115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024095">
        <property type="entry name" value="Vesicle_P115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006953">
        <property type="entry name" value="Vesicle_Uso1_P115_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013:SF0">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04871">
        <property type="entry name" value="Uso1_p115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04869">
        <property type="entry name" value="Uso1_p115_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="5">
        <location>
            <begin position="334"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="Uso1/p115-like vesicle tethering protein C-terminal" evidence="6">
        <location>
            <begin position="794"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="719"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="785"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="927" mass="98301" checksum="B938E849245B206E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXV6</accession>
    <name>A4RXV6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YlxR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="Gramene" id="ABO96356">
        <property type="protein sequence ID" value="ABO96356"/>
        <property type="gene ID" value="OSTLU_31832"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31832"/>
    <dbReference type="HOGENOM" id="CLU_878229_0_0_1"/>
    <dbReference type="OMA" id="RASCHAT"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="YlxR-like_sf"/>
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        <property type="entry name" value="YlxR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215">
        <property type="entry name" value="BLL0784 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215:SF1">
        <property type="entry name" value="YLXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YlxR-like"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="2">
        <location>
            <begin position="71"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="317" mass="35028" checksum="F40191C4815B8C91" modified="2007-05-15" version="1">MSRARGIARATRGGEVARRAVATTSTATATATRDDDDATGERLKRALRRCDDAWALDGTTHGARLALMPRRRCVGVNAHFPRALLVRYVLAMDGEKRRWVAPDARGEREGRGAYASADPRALEMAMKKRGFEMAFKTKDIHVPEKLAEMTRRQLRAHVRELFARACGSAREALAGNAGNGEESRAQTTPRTVEEEIEKLIETQKRIVAEDWILIPSDSRARDGAGDDETHEERRGSAESDAVRGVGYKLDALSMDELTACLDAADADESVLKRIRDGLKKFQTTGNLSDAPKLVDVNEDVSLGLRITQIKVKLFERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYC1</accession>
    <name>A4RYC1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">VHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_24632</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418360.1">
        <property type="nucleotide sequence ID" value="XM_001418323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYC1"/>
    <dbReference type="STRING" id="436017.A4RYC1"/>
    <dbReference type="GeneID" id="5002237"/>
    <dbReference type="Gramene" id="ABO96653">
        <property type="protein sequence ID" value="ABO96653"/>
        <property type="gene ID" value="OSTLU_24632"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24632"/>
    <dbReference type="eggNOG" id="KOG1087">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_505694_0_0_1"/>
    <dbReference type="OrthoDB" id="2018246at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13856:SF137">
        <property type="entry name" value="GH05942P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13856">
        <property type="entry name" value="VHS DOMAIN CONTAINING PROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="4">
        <location>
            <begin position="25"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="5">
        <location>
            <begin position="282"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="408"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="505"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96653.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="58245" checksum="EDCB7A9E80630D36" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="7">BEACH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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    </gene>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418194.1">
        <property type="nucleotide sequence ID" value="XM_001418157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYN0"/>
    <dbReference type="GeneID" id="5002216"/>
    <dbReference type="Gramene" id="ABO96487">
        <property type="protein sequence ID" value="ABO96487"/>
        <property type="gene ID" value="OSTLU_41455"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41455"/>
    <dbReference type="eggNOG" id="KOG1787">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000218_3_0_1"/>
    <dbReference type="OMA" id="SPMSNRW"/>
    <dbReference type="OrthoDB" id="26681at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1540.10:FF:000001">
        <property type="entry name" value="neurobeachin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050865">
        <property type="entry name" value="BEACH_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743:SF157">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743">
        <property type="entry name" value="BEIGE/BEACH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14844">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="3">
        <location>
            <begin position="77"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="42879" checksum="48A2AF603EF67FFD" modified="2007-05-15" version="1" fragment="single">MIFYTEDNSHVWSWPLEHLHQVQSRRYLLRRSALEFFMLDRMTYFIDFGTAEQRRQVFRVLIKLKPKNFVPLYLETSKPEALLRKSDITSRWIRREISNFDYIMALNTLAGRSYQDITQYPVFPWVLTDYTSETLDLSNPDVYRDLRKPIGALNPDRLARIKERYDFFDDPEIPKFHYGSHYSSSGTVLFYLLRVDPFTTLAYELQGGKFDHADRLFHDIASTWKSCYNDMSDVKELVPEFFYLPEMFKNVNNIDFGVTQSGEKVDAVILPPWAKSPEDFVAKQREALESDYVSKNLHHWVDLIFGYKQRGKAAESACNVFYYMTYEGAVDVEAIQDPILLKATQDQIACFGQTPSQLLTIPHPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYQ6</accession>
    <name>A4RYQ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiol-disulfide oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_10574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418204.1">
        <property type="nucleotide sequence ID" value="XM_001418167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYQ6"/>
    <dbReference type="GeneID" id="5002567"/>
    <dbReference type="Gramene" id="ABO96497">
        <property type="protein sequence ID" value="ABO96497"/>
        <property type="gene ID" value="OSTLU_10574"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10574"/>
    <dbReference type="eggNOG" id="ENOG502RXZ4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086500_2_1_1"/>
    <dbReference type="OMA" id="WLYAPLR"/>
    <dbReference type="OrthoDB" id="441708at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042246">
        <property type="term" value="P:tissue regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044691">
        <property type="entry name" value="DCC1_Trx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34290:SF2">
        <property type="entry name" value="OS04G0668800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34290">
        <property type="entry name" value="SI:CH73-390P7.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14274" checksum="F53CDF76ABE2AF6E" modified="2007-05-15" version="1" fragment="single">SWEFRLLYDGACPLCVREVEMLRAKDGGKGNLDLVDIASDDYDAKENAGIEYAEAMKTIHGLDAANNVYTGVEVFEKAYKAVGLGYVYAFTKVPFLLNAANKVYDVWAKYRLNVTSRGSLAEHLAARKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYS9</accession>
    <name>A4RYS9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418216.1">
        <property type="nucleotide sequence ID" value="XM_001418179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYS9"/>
    <dbReference type="GeneID" id="5002311"/>
    <dbReference type="Gramene" id="ABO96509">
        <property type="protein sequence ID" value="ABO96509"/>
        <property type="gene ID" value="OSTLU_15756"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15756"/>
    <dbReference type="HOGENOM" id="CLU_593672_0_0_1"/>
    <dbReference type="OMA" id="TWDTRVL"/>
    <dbReference type="OrthoDB" id="498086at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="461" mass="50392" checksum="C31B958943C04FF0" modified="2007-05-15" version="1">MKTVARKTSVWSNALAASATVADATTARDDARAKGASFEARGEDEEARVRRAASELRVKLLDEIVRGAAKREPSDEDGVRGSEDADARRARRAGRDAFLAATAKDGDEDEDAIARMRAAVNFVMGFCAEILQPSDDGGSPAVMPPLGTHVILRADVEAEGERSVYFQEQCSYDFDEIRTADHFIDYERQFVHASAKVQTAPRVSTSGSVIDVHFDLPKPSDSSTTNNIREGNFVEVRGCSGHPDYLGRRGECNNSGEVFEFNLPSLRISGLGRAYPVAEIVGEVTVRGCTSGLKTSLKFRPFDVETSPSFRNIVSGTMVRNNTEVKRLILGTWDTRVLLGCICEDRDSLDDVLHAARDFKVPPLTTATGVRSLLQALESPGSMSNKRLWQTIVEALRVANLHEPERSVVQEVLGEPATATREKIEEGSTMAYELAVIVANSPPPDAPPPLPRYWSPRTKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYY6</accession>
    <name>A4RYY6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TFIIB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_94516</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418474.1">
        <property type="nucleotide sequence ID" value="XM_001418437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYY6"/>
    <dbReference type="STRING" id="436017.A4RYY6"/>
    <dbReference type="GeneID" id="5002495"/>
    <dbReference type="Gramene" id="ABO96767">
        <property type="protein sequence ID" value="ABO96767"/>
        <property type="gene ID" value="OSTLU_94516"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94516"/>
    <dbReference type="eggNOG" id="KOG1598">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1192507_0_0_1"/>
    <dbReference type="OMA" id="HYEKRGE"/>
    <dbReference type="OrthoDB" id="511529at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF70">
        <property type="entry name" value="PLANT-SPECIFIC TFIIB-RELATED PROTEIN PTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="4">
        <location>
            <begin position="16"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="233" mass="25038" checksum="63AE1D3C0A7618BA" modified="2007-05-15" version="1" fragment="single">MDLAHHGEYAADDPGAARVPACPNCGKHEIKLEPALGSEICQACGVVYNASVLQTTLNWTEDGAADGTFLQDGAHVGAHLAAARAQMVSMPGASHVTRNMFRDRESTNLYHIAKSVEHTGALLKLNKDIIAEVKDLVTRASDGKWGQGLWTSQLTGACVYSVCRQNNLPVSMREVAEACSVNVFTLGRVFHKLQELHGLKMPPLDPENYVARAVAALPELAAISNKNSTVQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ37</accession>
    <name>A4RZ37_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_15835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418262.1">
        <property type="nucleotide sequence ID" value="XM_001418225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ37"/>
    <dbReference type="STRING" id="436017.A4RZ37"/>
    <dbReference type="GeneID" id="5002593"/>
    <dbReference type="Gramene" id="ABO96555">
        <property type="protein sequence ID" value="ABO96555"/>
        <property type="gene ID" value="OSTLU_15835"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15835"/>
    <dbReference type="eggNOG" id="KOG3109">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1430225_0_0_1"/>
    <dbReference type="OMA" id="INLACRE"/>
    <dbReference type="OrthoDB" id="1065058at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12725">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12725:SF117">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO96555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="190" mass="20876" checksum="C95D6C2E835B2E3E" modified="2007-05-15" version="1">MTAAEAAATRKTAFAKASQCYKGLRDLGLDVESQEAFTAYCRAGAETFLKPDAALAECLRAMPYRKVVMTNTSETEGMKALTALGLDASSSDAFEKVYGGIFTAPACKPQREAFEKVFADLGRDVDPRRCVMFEDSMKNVKAAKSFGMTTVFVRTRGESVLDDDVEACCDAVVDEIEFEQLRRQLPELFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZF6</accession>
    <name>A4RZF6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418322.1">
        <property type="nucleotide sequence ID" value="XM_001418285.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RZF6"/>
    <dbReference type="GeneID" id="5002374"/>
    <dbReference type="Gramene" id="ABO96615">
        <property type="protein sequence ID" value="ABO96615"/>
        <property type="gene ID" value="OSTLU_32368"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32368"/>
    <dbReference type="eggNOG" id="KOG1910">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_228789_0_0_1"/>
    <dbReference type="OMA" id="TPGACAQ"/>
    <dbReference type="OrthoDB" id="514036at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1216"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1592"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2348"/>
            <end position="2378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2400"/>
            <end position="2423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2438"/>
            <end position="2466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1595"/>
            <end position="1615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2362"/>
            <end position="2377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2407"/>
            <end position="2423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="2466" mass="272288" checksum="94D0D2FD0461879C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZR5</accession>
    <name>A4RZR5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_16020</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">PML body</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418843.1">
        <property type="nucleotide sequence ID" value="XM_001418806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZR5"/>
    <dbReference type="STRING" id="436017.A4RZR5"/>
    <dbReference type="GeneID" id="5002671"/>
    <dbReference type="Gramene" id="ABO97136">
        <property type="protein sequence ID" value="ABO97136"/>
        <property type="gene ID" value="OSTLU_16020"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16020"/>
    <dbReference type="eggNOG" id="KOG2756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050478_0_0_1"/>
    <dbReference type="OMA" id="IMMSNDK"/>
    <dbReference type="OrthoDB" id="9975959at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070260">
        <property type="term" value="F:5'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09080">
        <property type="entry name" value="TDP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051547">
        <property type="entry name" value="TDP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15822">
        <property type="entry name" value="TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15822:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Exo_endo_phos"/>
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    </dbReference>
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        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="47"/>
            <end position="297"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO97136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="325" mass="36593" checksum="BB7F24160411AB34" modified="2007-05-15" version="1">MTMVNAPSAGEKTSETLRATAAPAKPKANAEDSREGVAIEKGDLRLLTYNVWFGDVAQAERLEALGKVIETCDAHVVCLQEVTPQALFVLRAQPWWDAYVVGPKPPLQEYFSMMLFKRVVRSEVLKRDQYAFRNSQMGRYLDVVSHMRCPSSRATFALGTSHLESYISASRTSARERAVQMSECFSWLNQHENAIFMGDTNWDDKDGAVPLPDGWRDAWLEARPGDPGFTYDARKNAMLRGYLQKRLDRAFVKLKHFDVKRVEMVGTDPIPGVTYHKTVSNRGKAQILELPVVPSDHFGLLLTLRGKSRKLDERGGNDIETVDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZR6</accession>
    <name>A4RZR6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SUEL-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_24759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418844.1">
        <property type="nucleotide sequence ID" value="XM_001418807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZR6"/>
    <dbReference type="STRING" id="436017.A4RZR6"/>
    <dbReference type="GeneID" id="5003046"/>
    <dbReference type="Gramene" id="ABO97137">
        <property type="protein sequence ID" value="ABO97137"/>
        <property type="gene ID" value="OSTLU_24759"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24759"/>
    <dbReference type="HOGENOM" id="CLU_845539_0_0_1"/>
    <dbReference type="OMA" id="CELLWCW"/>
    <dbReference type="OrthoDB" id="10491906at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002673082" description="SUEL-type lectin domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="34404" checksum="CFF4BDA828B461C0" modified="2007-05-15" version="1">MPRARSTAALVAVALVARVATTAGAALASSCAPPRFSCASARATVDDASKCHASFRCRIVCSPSASCVETFTIRAGEATLPTGETVTFNASTRERSALGPTTYGGDAACSAVGCDAYATRLTTQNAALTERYDGKFCEVRETSERCALEGAPKDGSWTEFTVTMKCRNKILPCGARAVAEIDFLGVVGSVAPGAPSPPTPPDAPPMPPKPPPPPPPPSTFAKGGAGRAALRAALVVALSAVVAYAALGGAYVWALERGWVEGIAEPCWERDGAFCELLWCWCAPAYWRASDEECLAAYEGRAAAETATREDVAQTTAPLLGNASSDDDDDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S000</accession>
    <name>A4S000_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">TH1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_93007</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NELF-D family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418887.1">
        <property type="nucleotide sequence ID" value="XM_001418850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S000"/>
    <dbReference type="STRING" id="436017.A4S000"/>
    <dbReference type="GeneID" id="5002821"/>
    <dbReference type="Gramene" id="ABO97180">
        <property type="protein sequence ID" value="ABO97180"/>
        <property type="gene ID" value="OSTLU_93007"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93007"/>
    <dbReference type="eggNOG" id="ENOG502QPUE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_416458_0_0_1"/>
    <dbReference type="OMA" id="CHSEHTY"/>
    <dbReference type="OrthoDB" id="511287at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032021">
        <property type="term" value="C:NELF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034244">
        <property type="term" value="P:negative regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006942">
        <property type="entry name" value="TH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12144:SF0">
        <property type="entry name" value="NEGATIVE ELONGATION FACTOR C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12144">
        <property type="entry name" value="NEGATIVE ELONGATION FACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04858">
        <property type="entry name" value="TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="659" mass="70728" checksum="EDEA5F18621A6C3E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4S043</accession>
    <name>A4S043_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ycf49-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_9615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418680.1">
        <property type="nucleotide sequence ID" value="XM_001418643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S043"/>
    <dbReference type="STRING" id="436017.A4S043"/>
    <dbReference type="GeneID" id="5002754"/>
    <dbReference type="Gramene" id="ABO96973">
        <property type="protein sequence ID" value="ABO96973"/>
        <property type="gene ID" value="OSTLU_9615"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9615"/>
    <dbReference type="eggNOG" id="ENOG502RZEV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093295_2_0_1"/>
    <dbReference type="OMA" id="ACTWHYF"/>
    <dbReference type="OrthoDB" id="196633at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019634">
        <property type="entry name" value="Uncharacterised_Ycf49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33833">
        <property type="entry name" value="NUCLEOLAR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33833:SF3">
        <property type="entry name" value="YCF49-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10693">
        <property type="entry name" value="DUF2499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="9818" checksum="C8C1DB8BBE5F49F7" modified="2007-05-15" version="1" fragment="single">NALSLPTWVIHVSSLVEWLIAMGLAWEYAEVTKRPAWKGLTLGMIPCHASGIAACTFHLFYNAPALNSVVAMQALLTVVGNTTCALASYRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S067</accession>
    <name>A4S067_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_32634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418922.1">
        <property type="nucleotide sequence ID" value="XM_001418885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S067"/>
    <dbReference type="STRING" id="436017.A4S067"/>
    <dbReference type="GeneID" id="5002764"/>
    <dbReference type="Gramene" id="ABO97215">
        <property type="protein sequence ID" value="ABO97215"/>
        <property type="gene ID" value="OSTLU_32634"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32634"/>
    <dbReference type="eggNOG" id="ENOG502SNXY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115159_0_0_1"/>
    <dbReference type="OMA" id="DETRACC"/>
    <dbReference type="OrthoDB" id="547106at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005082">
        <property type="entry name" value="Peptidase_U9_T4_prohead"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03420">
        <property type="entry name" value="Peptidase_S77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="207" mass="22883" checksum="D54EAB21430B2802" modified="2007-05-15" version="1">MGVCVSVHTVERALADEAEIERRSRVDALARSLANNKGELYLHGVLARCDRVNRNGRVYPKPILHREVAAYVAARVRRGRAYGKLEHPAATDEAEFRDADDETRACCRVVDVYWCDGDRTLMGYVKILDTESGRAIREIYEGGGLVGASTRSWSSLETRADGKCYVDDDLELLAFDLVRDPATISLSANGLLTPVRGAVEGRGERLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0A4</accession>
    <name>A4S0A4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="1">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the Smc5-Smc6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSE1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="1"/>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418712.1">
        <property type="nucleotide sequence ID" value="XM_001418675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0A4"/>
    <dbReference type="STRING" id="436017.A4S0A4"/>
    <dbReference type="GeneID" id="5003029"/>
    <dbReference type="Gramene" id="ABO97005">
        <property type="protein sequence ID" value="ABO97005"/>
        <property type="gene ID" value="OSTLU_32670"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32670"/>
    <dbReference type="eggNOG" id="KOG4718">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1279193_0_0_1"/>
    <dbReference type="OMA" id="DGHVCNG"/>
    <dbReference type="OrthoDB" id="185455at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="27448" checksum="ADC4F9E95E5B1684" modified="2007-05-15" version="1">MPPAAAAKRKAKPLAATSPSPVKKNAKTTAPAASNDDASALSVQQQCFLQALLSRGIVESEDAEALYREIVEDDAANEFTRFWGEIAVALKFLDLDIRTGKFEGDGKTYMAVVNQGTTEVAKLATRMTPAEIALFRVAMLEILRDDSSAERGIDFMSALNSTELQLTQDASTQDGATQMTQLEKQTQTVQKMSKVVKDAALNDLVAERWLERVDDGRRLTLGPRSFLELREFILAQAPERARARWDKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0F3</accession>
    <name>A4S0F3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CobW C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_3375</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418735.1">
        <property type="nucleotide sequence ID" value="XM_001418698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0F3"/>
    <dbReference type="STRING" id="436017.A4S0F3"/>
    <dbReference type="GeneID" id="5002943"/>
    <dbReference type="Gramene" id="ABO97028">
        <property type="protein sequence ID" value="ABO97028"/>
        <property type="gene ID" value="OSTLU_3375"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3375"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_0_0_1"/>
    <dbReference type="OMA" id="HSQGFET"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF62">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="7">
        <location>
            <begin position="294"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="222"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="388" mass="42900" checksum="52B359C78FE2BF8A" modified="2007-05-15" version="1" fragment="single">DSRVPVTILTGFLGSGKTTLLNHVLKAEHGKRIVVIENEFGEVDIDGELVAFRESGDEDIMLLNNGCLCCTVRSDLVEMLMRLVKEKKGMFDHILIETTGLANPAPIIQTFYLEPALLDSLRLDGVVTLVDAKHAELHLDEVKPAGVVNESLEQVAFADRIVLNKTDLVTDAQANALEYRLRTINDLAKIGRASMAKVDLDFVLGVGGFDLERVQDQVLPDEPKKTEAHDHGHSHAAGEESCEKCDHDDGHSHSHGEEHSHSHAHSHGVEADADCEVCGEHGHSHSHHVHDDAVGSVSLSLDGDLDLDLVNDWLGLLLNERWEDLYRMKGVLAIQGCDERYVFQGVHALFEGMPDRAWKADETRSSKLVFIGKDLDRAELQRDFEACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0R9</accession>
    <name>A4S0R9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418788.1">
        <property type="nucleotide sequence ID" value="XM_001418751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0R9"/>
    <dbReference type="STRING" id="436017.A4S0R9"/>
    <dbReference type="GeneID" id="5002848"/>
    <dbReference type="Gramene" id="ABO97081">
        <property type="protein sequence ID" value="ABO97081"/>
        <property type="gene ID" value="OSTLU_32842"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32842"/>
    <dbReference type="eggNOG" id="ENOG502QW6Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_461840_0_0_1"/>
    <dbReference type="OMA" id="TLPHISM"/>
    <dbReference type="OrthoDB" id="2017000at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471:SF1">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="347"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="591" mass="67555" checksum="F9C48DEA4AF65927" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0W9</accession>
    <name>A4S0W9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DNA 5'-3' helicase FANCJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_32894</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419051.1">
        <property type="nucleotide sequence ID" value="XM_001419014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0W9"/>
    <dbReference type="STRING" id="436017.A4S0W9"/>
    <dbReference type="GeneID" id="5003237"/>
    <dbReference type="Gramene" id="ABO97344">
        <property type="protein sequence ID" value="ABO97344"/>
        <property type="gene ID" value="OSTLU_32894"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32894"/>
    <dbReference type="eggNOG" id="KOG1132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006515_1_0_1"/>
    <dbReference type="OMA" id="FSNDNAR"/>
    <dbReference type="OrthoDB" id="497061at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000731">
        <property type="entry name" value="Fanconi anemia group J protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF47">
        <property type="entry name" value="FANCONI ANEMIA GROUP J PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="39"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="785"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="825"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00082714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO97344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1067" mass="117443" checksum="F80A0E2113809B17" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0X0</accession>
    <name>A4S0X0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_4637</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419260.1">
        <property type="nucleotide sequence ID" value="XM_001419223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0X0"/>
    <dbReference type="STRING" id="436017.A4S0X0"/>
    <dbReference type="GeneID" id="5003424"/>
    <dbReference type="Gramene" id="ABO97553">
        <property type="protein sequence ID" value="ABO97553"/>
        <property type="gene ID" value="OSTLU_4637"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4637"/>
    <dbReference type="eggNOG" id="KOG2667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034705_1_0_1"/>
    <dbReference type="OMA" id="RAPCDFL"/>
    <dbReference type="OrthoDB" id="270930at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="130"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="310" mass="34517" checksum="413A3C7BB92FC863" modified="2007-05-15" version="1" fragment="single">VDAFARAAPHLTKRTRAGACVSVVGVVLACALALVEITDFLTPTRAKTHGVDDARNATLRIEIDVTFPRMPCQLLYVDAYDESGKHEVDARGLLLKTRLDASGRAIGEYESAGGVDLGGLVLFQRRPEHAHEVREAKADVEGCRLHGELEARRVAGTLRASTGPESYEFLKEIYDEPWEIDMRHAVKTFTFGAEFPGAVNPMNGVRRMETKSGIYKYFMKVVPTTYSSTRALFGFIPWTVRTRTNQYSVTEHFIETPHWGALPQLFFIYDLSAIAVNITVTSKSIVYFLTKTLATMGGIFALTRTVDRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Z7</accession>
    <name>A4S0Z7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_42459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419063.1">
        <property type="nucleotide sequence ID" value="XM_001419026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Z7"/>
    <dbReference type="STRING" id="436017.A4S0Z7"/>
    <dbReference type="GeneID" id="5003399"/>
    <dbReference type="Gramene" id="ABO97356">
        <property type="protein sequence ID" value="ABO97356"/>
        <property type="gene ID" value="OSTLU_42459"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42459"/>
    <dbReference type="eggNOG" id="KOG2650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065471_0_0_1"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06227">
        <property type="entry name" value="M14-CPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034269">
        <property type="entry name" value="At5g42320_M14_CPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF119">
        <property type="entry name" value="OS02G0119300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M14" evidence="4">
        <location>
            <begin position="1"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="356" mass="39355" checksum="40B296427E7115BC" modified="2007-05-15" version="1">MTTETREDATDGYRARVDVVYARLSGADAREDGDKLRVLLNYGEHGRELVPVDAAVRLLETMAEGEDAVVALARGRGVDETRLRAMLRATTFAVVPMENERGRELVERGDPCERKNGRGVDPNRNWGVNWGVKAPDYDPKEEFPGTAPFSEPESRIFRDLVASFEPHAVVNWHSGMSAIFTPYDHVAREPTGAGAEAMMRFARVIDAEHCAKKCTLGSGGKGVGYLAHGTATDYIYEKMKVPVVYTWEIYGDLDAPFEDCHRAFNPTTKETRDAVVEAWFGAPITLVSMLDQHPDINFKHQSVVPAVASSSSFAVGDEQRRFPWTISLAFAFFTLVALRRLRRSKRGGGAAIGTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1A2</accession>
    <name>A4S1A2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trafficking protein particle complex subunit 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_87978</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_87978"/>
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            <begin position="294"/>
            <end position="547"/>
        </location>
    </feature>
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            <end position="106"/>
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        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
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                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Jabbari K."/>
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                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">CCE9901</strain>
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        <property type="component" value="Chromosome 8"/>
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    </dbReference>
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    </feature>
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        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO97642.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
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    </evidence>
    <sequence length="62" mass="6678" checksum="267C44CA630AE82F" modified="2007-05-15" version="1" fragment="single">MGDAHYRALGVEASASAAEIKRAFAKRARECHPDKGGSAESFAAVRKAYECLSDVKARSTYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1H8</accession>
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        <recommendedName>
            <fullName evidence="3">RCC1-like domain-containing protein</fullName>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Jabbari K."/>
                <person name="Bowler C."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            <dbReference type="PubMed" id="17460045"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">CCE9901</strain>
        </source>
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        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
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        <location>
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            <end position="204"/>
        </location>
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        <location>
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    <feature type="non-terminal residue" evidence="4">
        <location>
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    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF25390"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
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    </evidence>
    <sequence length="212" mass="22087" checksum="0439D63F45846D49" modified="2007-05-15" version="1" fragment="single">VAAGGRYSVAVTSGQECLTWGEDVGGCTGHGESGLNRIHNTPKWMYWMTNATTKVVSCAAGSAHTVITTGSGQVYTFGVGDCGQLGHGDGVNYAKPKLVESVTLMNVSSVACGSNHTLVVTDSGYVYGFGSNSCGQLGCGDFSNIFIPRRMGHDEFVGGVVQVVGGEEHTVMLTEKGRVYVCGRGSDGQLGLSDTVDRSLVTLVSTMVNVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Q0</accession>
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        <recommendedName>
            <fullName evidence="1">Protein SirB1 N-terminal domain-containing protein</fullName>
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        <name evidence="2" type="ORF">OSTLU_6509</name>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419186.1">
        <property type="nucleotide sequence ID" value="XM_001419149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Q0"/>
    <dbReference type="STRING" id="436017.A4S1Q0"/>
    <dbReference type="GeneID" id="5003186"/>
    <dbReference type="Gramene" id="ABO97479">
        <property type="protein sequence ID" value="ABO97479"/>
        <property type="gene ID" value="OSTLU_6509"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6509"/>
    <dbReference type="eggNOG" id="ENOG502R2Y6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063810_1_0_1"/>
    <dbReference type="OrthoDB" id="28868at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350:SF21">
        <property type="entry name" value="F-BOX ONLY PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350">
        <property type="entry name" value="SI:DKEY-261L7.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein SirB1 N-terminal" evidence="1">
        <location>
            <begin position="28"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="216" mass="24559" checksum="F90513E1A9611AC7" modified="2007-05-15" version="1" fragment="single">KEDEDDVDLLACACYVAAHANPDIDVEDVRREIDACAALVRRRLDADVDARFPLRTIKTISRAWSTDLGFKGNVENYYEVENSCVDDVLRRKVGIPITLCLMYMEIAKRVGVDMVDVGIPGHLLCRPLAEGMEVLVDPFNQGDVLFIEEVEDILSKNSLFGEGGKVQIERSFLQETKIRKKAFLTRMLVNLKSIYFAREDYERALQITEYMMACNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1S0</accession>
    <name>A4S1S0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">OSTLU_16541</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasmic vesicle</location>
            <location evidence="11">COPII-coated vesicle membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419416.1">
        <property type="nucleotide sequence ID" value="XM_001419379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1S0"/>
    <dbReference type="STRING" id="436017.A4S1S0"/>
    <dbReference type="GeneID" id="5003110"/>
    <dbReference type="Gramene" id="ABO97709">
        <property type="protein sequence ID" value="ABO97709"/>
        <property type="gene ID" value="OSTLU_16541"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16541"/>
    <dbReference type="eggNOG" id="KOG1986">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008658_3_0_1"/>
    <dbReference type="OMA" id="FPPHYAE"/>
    <dbReference type="OrthoDB" id="10256289at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11287">
        <property type="entry name" value="Sec23_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.730:FF:000005">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.380:FF:000001">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000014">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037550">
        <property type="entry name" value="Sec23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF0">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="14">
        <location>
            <begin position="43"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="15">
        <location>
            <begin position="114"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="17">
        <location>
            <begin position="397"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="16">
        <location>
            <begin position="522"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="13">
        <location>
            <begin position="639"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="191"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABO97709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="770" mass="84191" checksum="9433E9D3E2B2ADF6" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S212</accession>
    <name>A4S212_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_16609</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419245.1">
        <property type="nucleotide sequence ID" value="XM_001419208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S212"/>
    <dbReference type="STRING" id="436017.A4S212"/>
    <dbReference type="GeneID" id="5003103"/>
    <dbReference type="Gramene" id="ABO97538">
        <property type="protein sequence ID" value="ABO97538"/>
        <property type="gene ID" value="OSTLU_16609"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16609"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OMA" id="DQKSHIE"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF8">
        <property type="entry name" value="7ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="266" mass="27436" checksum="C6066815A5FACE3D" modified="2007-05-15" version="1">MSSNFAFDAAGKVVVVTGGGRGIGAGIVDAFARQHGAKRVYSVSRSTEDTVLKPSTASGGEIVGVSADLSTPDGAAKVASTIAARGDDLVHVLVHNSGASWGAELESHDDKGFVKTYQLNVMGTWRLTVALLPHLMKAGTPQDPARVIVIGSIAGIRPQKYPTFSYDASKAALHHLALKLADEFARKRALDITVNVVAPGYIPTKMSAGLTKYGESSDDIVASSVPLRRAGAPADVAGAVAFLSSDAAAWITGVVLPVDGGFLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S292</accession>
    <name>A4S292_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BAT2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_33369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419493.1">
        <property type="nucleotide sequence ID" value="XM_001419456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S292"/>
    <dbReference type="STRING" id="436017.A4S292"/>
    <dbReference type="GeneID" id="5003580"/>
    <dbReference type="Gramene" id="ABO97786">
        <property type="protein sequence ID" value="ABO97786"/>
        <property type="gene ID" value="OSTLU_33369"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33369"/>
    <dbReference type="HOGENOM" id="CLU_498202_0_0_1"/>
    <dbReference type="OMA" id="GYHHGRR"/>
    <dbReference type="OrthoDB" id="10656002at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="58693" checksum="401FC28F32408B45" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2C3</accession>
    <name>A4S2C3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_33401</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the 19S regulatory particle (RP/PA700) base subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700). The RP/PA700 complex is composed of at least 17 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the proteasome subunit S2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419727.1">
        <property type="nucleotide sequence ID" value="XM_001419690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2C3"/>
    <dbReference type="STRING" id="436017.A4S2C3"/>
    <dbReference type="GeneID" id="5003728"/>
    <dbReference type="Gramene" id="ABO98020">
        <property type="protein sequence ID" value="ABO98020"/>
        <property type="gene ID" value="OSTLU_33401"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33401"/>
    <dbReference type="eggNOG" id="KOG2005">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008705_1_0_1"/>
    <dbReference type="OMA" id="GTCNGDI"/>
    <dbReference type="OrthoDB" id="10252509at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016643">
        <property type="entry name" value="26S_Psome_Rpn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041433">
        <property type="entry name" value="RPN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040892">
        <property type="entry name" value="RPN1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18051">
        <property type="entry name" value="RPN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17781">
        <property type="entry name" value="RPN1_RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015965">
        <property type="entry name" value="26S_Psome_Rpn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RPN1 N-terminal" evidence="6">
        <location>
            <begin position="66"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit RPN1 C-terminal" evidence="7">
        <location>
            <begin position="864"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="923" mass="100351" checksum="60591E91D165A11F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2R6</accession>
    <name>A4S2R6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pantoate--beta-alanine ligase</fullName>
            <ecNumber evidence="3">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Pantoate-activating enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pantothenate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_35160</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(R)-pantoate + beta-alanine + ATP = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419794.1">
        <property type="nucleotide sequence ID" value="XM_001419757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2R6"/>
    <dbReference type="STRING" id="436017.A4S2R6"/>
    <dbReference type="GeneID" id="5003787"/>
    <dbReference type="Gramene" id="ABO98087">
        <property type="protein sequence ID" value="ABO98087"/>
        <property type="gene ID" value="OSTLU_35160"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35160"/>
    <dbReference type="eggNOG" id="KOG3042">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047148_2_0_1"/>
    <dbReference type="OMA" id="CNHKLEP"/>
    <dbReference type="OrthoDB" id="2020436at2759"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="entry name" value="Pantoate-beta-alanine ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299">
        <property type="entry name" value="CYTIDYLATE KINASE/PANTOATE-BETA-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PANTOATE--BETA-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="290" mass="31854" checksum="479BE83C68C32646" modified="2007-05-15" version="1">MEIITDAREMRAWTRARRARGERVAFVPTMGALHEGHLALVDIARARCACDAVVLSVYVNETQFAPGEDFDAYPRVGDADERAARARGVDCVFAPKRMYANEGEGEGAAHETYVEVAELSKGLCAKTRPHFFKGVATIVTKLFNVVEPDAAVFGKKDYQQWRVIRRMARDLDFDIDVVGGEIVRESDGLAMSSRNLLLTTENREKATVIYQSLSEAKATAERAPTTSDALVTRVSERIRDGGGEVDYVQAMEPESLTPYVGVLDSPCVIAVAAKFGSVRLLDNVEIMCGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2T7</accession>
    <name>A4S2T7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419593.1">
        <property type="nucleotide sequence ID" value="XM_001419556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2T7"/>
    <dbReference type="GeneID" id="5003805"/>
    <dbReference type="Gramene" id="ABO97886">
        <property type="protein sequence ID" value="ABO97886"/>
        <property type="gene ID" value="OSTLU_33563"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33563"/>
    <dbReference type="HOGENOM" id="CLU_1196567_0_0_1"/>
    <dbReference type="OMA" id="MAFATMY"/>
    <dbReference type="OrthoDB" id="10602795at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="232" mass="26868" checksum="88066186FCB4EEBA" modified="2007-05-15" version="1">MSSFVKAGSYDPTLVDVELTAEEAKTRANRRDAFREHLRATLAEKELVGAFAKMYRMNEKPKDPLQWLLDYFERDQREHIRRAEETAETYRSELLRAEQERDSLIAKMEVMRQKVSNLERTVQELRDGGRKHVVGVYGGEEMPTGADAPAPAEKENDKKEKKEKKEKKEKKEKKEKKEKKEKESAARPPSDDEFFGNSKETFGSMKMKTTPDMFDDSDSSSLPKQQSLRDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2V8</accession>
    <name>A4S2V8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SDG3518</name>
        <name evidence="6" type="ORF">OSTLU_34722</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419603.1">
        <property type="nucleotide sequence ID" value="XM_001419566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2V8"/>
    <dbReference type="GeneID" id="5003816"/>
    <dbReference type="Gramene" id="ABO97896">
        <property type="protein sequence ID" value="ABO97896"/>
        <property type="gene ID" value="OSTLU_34722"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34722"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037565_1_1_1"/>
    <dbReference type="OMA" id="QEWSVLA"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19179">
        <property type="entry name" value="SET_RBCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044431">
        <property type="entry name" value="SET_RBCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF123">
        <property type="entry name" value="RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE_OXYGENASE SMALL SUBUNIT N-METHYLTRANSFERASE I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="86"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="524" mass="56992" checksum="0DB5BD94404B6E24" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3Y4</accession>
    <name>A4S3Y4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_26214</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting at the trans-Golgi network and early endosomes (TGN/EE). The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420001.1">
        <property type="nucleotide sequence ID" value="XM_001419964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3Y4"/>
    <dbReference type="STRING" id="436017.A4S3Y4"/>
    <dbReference type="GeneID" id="5003959"/>
    <dbReference type="Gramene" id="ABO98294">
        <property type="protein sequence ID" value="ABO98294"/>
        <property type="gene ID" value="OSTLU_26214"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26214"/>
    <dbReference type="eggNOG" id="KOG0934">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061221_0_0_1"/>
    <dbReference type="OMA" id="KAYHILD"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030121">
        <property type="term" value="C:AP-1 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016482">
        <property type="term" value="P:cytosolic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14831">
        <property type="entry name" value="AP1_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000007">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044733">
        <property type="entry name" value="AP1_sigma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00989">
        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="11">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00058887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="155" mass="18009" checksum="D9CD85DCD309A1BA" modified="2007-05-15" version="1">MIRFALLFSKQAKIRLSKYYVLTNQKERKRIERDVTSRIIPRANKLCNVVEYRDVKLVYRKYASLYFCLAVDRGANELATLEMIQHYVEILDKYFGNVCELDLVFNFHKAHYVLDEVFIAGHLQETSKKLIARLVGEHDALVERVKLGGPAAEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4C7</accession>
    <name>A4S4C7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_44133</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420410.1">
        <property type="nucleotide sequence ID" value="XM_001420373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4C7"/>
    <dbReference type="STRING" id="436017.A4S4C7"/>
    <dbReference type="GeneID" id="5004285"/>
    <dbReference type="Gramene" id="ABO98703">
        <property type="protein sequence ID" value="ABO98703"/>
        <property type="gene ID" value="OSTLU_44133"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44133"/>
    <dbReference type="eggNOG" id="KOG1940">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013368_2_0_1"/>
    <dbReference type="OMA" id="HATQNTR"/>
    <dbReference type="OrthoDB" id="497986at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16464">
        <property type="entry name" value="RING-H2_Pirh2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000208">
        <property type="entry name" value="Zinc finger protein-related isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039512">
        <property type="entry name" value="RCHY1_zinc-ribbon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017921">
        <property type="entry name" value="Znf_CTCHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037275">
        <property type="entry name" value="Znf_CTCHY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319:SF0">
        <property type="entry name" value="AND RING FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08900)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319">
        <property type="entry name" value="RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14599">
        <property type="entry name" value="zinc_ribbon_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161245">
        <property type="entry name" value="Zinc hairpin stack"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51270">
        <property type="entry name" value="ZF_CTCHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="6">
        <location>
            <begin position="159"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="CTCHY-type" evidence="7">
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            <end position="292"/>
        </location>
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        <location>
            <begin position="293"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="405" mass="45896" checksum="DD47C93A180FF4A9" modified="2007-05-15" version="1">MLIWVRNALNEDEREGMISSMRHATQNTRFAQWMNTWYSGKTNAADTAAVSSQDGMRQVHAYLSRRSGDVDKETFKPGWEDIFRMNQIQLEDAVRTVNRDDTLAPTKKAYLIQNLLASRWIVGNQLQAQKDKTTELSSVGSAQKSGAPAILCQPVDEDEENGKDGCKHYKRRCKIVAPCCDQAFTCRFCHDDASDHTVNRYAVKEMVCNECKKRQPVNEVCVGCSTSMAKYHCNVCNLFDDSSEAIYHCPFCNVCRRGKGLGVDFFHCMKCNACVSLQHGKHECSERGMDSECPVCKEFLAESETPVKELPCGHIMHATCFTTYTRHYYTCPLCRKSLGDFSMYFRMLDAILADESDDSVPEALRGKTQKVSCNDCAKDSDAKFHFVYHACAHCRSYNTRVLTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4D6</accession>
    <name>A4S4D6_OSTLU</name>
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        <recommendedName>
            <fullName evidence="3">Autophagy-related protein 13 N-terminal domain-containing protein</fullName>
        </recommendedName>
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    <gene>
        <name evidence="4" type="ORF">OSTLU_25201</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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            <end position="586"/>
        </location>
    </feature>
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            <end position="333"/>
        </location>
    </feature>
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        <location>
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            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="682" mass="71365" checksum="65B2958383666420" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4E1</accession>
    <name>A4S4E1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_5336</name>
    </gene>
    <organism evidence="8 9">
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="436017.A4S4E1"/>
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        <property type="gene ID" value="OSTLU_5336"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5336"/>
    <dbReference type="eggNOG" id="KOG3923">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034311_0_0_1"/>
    <dbReference type="OMA" id="DLWELQP"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="269"/>
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        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="293"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO98713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="310" mass="33953" checksum="E57DE3D2B2A4481A" modified="2007-05-15" version="1" fragment="single">VVVGGGVIGLTVALTLAERGMDVRVVAASFERTTSSVAAAFWFPFIVRTEPAALSDAWAIKSYEWYRELAREDGACGVEMRRCREFLKAPAPAAGWANAVEHYRALERGEHDEKYAGGYEFDVPVIAMPKFLPWLRTRCEALGVKFETRTLADVREARAFASNSERAFVVNCTGLGARRLVNDDLVKPVRGQVVYLKQDCGYGLFDDDPNALAYLIPRADCTVLGGTAQVDNDSLEPDDADERDIIAKCKRLWPELDETKVIGTNVGLRPSRTVVRCERDPADATLIHAYGHGGAGVTLCRGTALEVLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4G1</accession>
    <name>A4S4G1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420430.1">
        <property type="nucleotide sequence ID" value="XM_001420393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4G1"/>
    <dbReference type="GeneID" id="5004329"/>
    <dbReference type="Gramene" id="ABO98723">
        <property type="protein sequence ID" value="ABO98723"/>
        <property type="gene ID" value="OSTLU_26400"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26400"/>
    <dbReference type="eggNOG" id="ENOG502R1VP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089087_0_0_1"/>
    <dbReference type="OMA" id="FFPIIMD"/>
    <dbReference type="OrthoDB" id="1921626at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021467">
        <property type="entry name" value="DUF3119"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35550:SF2">
        <property type="entry name" value="OS05G0401200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11317">
        <property type="entry name" value="DUF3119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="267" mass="29533" checksum="4DB1FC3FF944BE76" modified="2007-05-15" version="1">MRCASALARASAPLNACARRTGRGARARDALALKRATVGVRRTIEIESIRPRTAARARASVATRASSLDDDVVVVPGDYRVGGVLLGVALLTGPALHLWTQFLVHGVLGGFLAFQASRVRFRFTRTDLEVVFIEPGADDSAALATDVASSGDNKLQGGGENRWAYDTITNWEFWWPGFPCLVYFKETQTKSDGQPHFFPIIMDGKMLYEVMLSRLPPSQNEKPSPSEWSLDLALEQTQIGRQIKENLNEDQLRQIKEMKGFPVLDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4H4</accession>
    <name>A4S4H4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">VIC family transporter: potassium ion channel subfamily H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_88568</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420439.1">
        <property type="nucleotide sequence ID" value="XM_001420402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4H4"/>
    <dbReference type="STRING" id="436017.A4S4H4"/>
    <dbReference type="GeneID" id="5004469"/>
    <dbReference type="Gramene" id="ABO98732">
        <property type="protein sequence ID" value="ABO98732"/>
        <property type="gene ID" value="OSTLU_88568"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88568"/>
    <dbReference type="eggNOG" id="KOG0498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_307449_0_0_1"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47823:SF9">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47823">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="210"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="852"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="919"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="852"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="935"/>
            <end position="949"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="962" mass="107005" checksum="83934B33B57D651F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4L0</accession>
    <name>A4S4L0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA m(6)A methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.348</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_43977</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:55584"/>
            <dbReference type="Rhea" id="RHEA-COMP:12414"/>
            <dbReference type="Rhea" id="RHEA-COMP:12417"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.348"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MT-A70-like family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.348" evidence="1"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420285.1">
        <property type="nucleotide sequence ID" value="XM_001420248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4L0"/>
    <dbReference type="SMR" id="A4S4L0"/>
    <dbReference type="STRING" id="436017.A4S4L0"/>
    <dbReference type="GeneID" id="5004353"/>
    <dbReference type="Gramene" id="ABO98578">
        <property type="protein sequence ID" value="ABO98578"/>
        <property type="gene ID" value="OSTLU_43977"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43977"/>
    <dbReference type="eggNOG" id="KOG2098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018702_1_0_1"/>
    <dbReference type="OMA" id="NRTGKMA"/>
    <dbReference type="OrthoDB" id="10262526at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036396">
        <property type="term" value="C:RNA N6-methyladenosine methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001734">
        <property type="term" value="F:mRNA m(6)A methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829:SF7">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO98578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="205" mass="23531" checksum="D8A74D7338DB84CC" modified="2007-05-15" version="1">MYEHEQFDVIMMDPPWQLATANPTRGVSLGYSQLTDQHIADLPLPQLQKNGLLFVWVINAKYQWCLNQFKKWGYEFVDEIVWVKVTKTRRLAKSHGFYLQHAKEVCLVARRGDAPPGLKNRAIGSDIIFAPRRGQSQKPTEIYELIEELVPNGRYLEIFARKNNLRDYWVSVGNEVTGTGLPPDDVKAFEERGHIPSAKYGASNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5F1</accession>
    <name>A4S5F1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_39213</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the 19S regulatory particle (RP/PA700) base subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420593.1">
        <property type="nucleotide sequence ID" value="XM_001420556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5F1"/>
    <dbReference type="STRING" id="436017.A4S5F1"/>
    <dbReference type="GeneID" id="5004678"/>
    <dbReference type="Gramene" id="ABO98886">
        <property type="protein sequence ID" value="ABO98886"/>
        <property type="gene ID" value="OSTLU_39213"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39213"/>
    <dbReference type="eggNOG" id="KOG2062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002323_0_0_1"/>
    <dbReference type="OMA" id="IMFGRQE"/>
    <dbReference type="OrthoDB" id="261572at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000017">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="749"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="8">
        <location>
            <begin position="11"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="7">
        <location>
            <begin position="765"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="826"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="929"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="844"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="869"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="940"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="963" mass="104083" checksum="7E0E9869EFA948E3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S633</accession>
    <name>A4S633_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420875.1">
        <property type="nucleotide sequence ID" value="XM_001420838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S633"/>
    <dbReference type="GeneID" id="5004864"/>
    <dbReference type="Gramene" id="ABO99168">
        <property type="protein sequence ID" value="ABO99168"/>
        <property type="gene ID" value="OSTLU_26973"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26973"/>
    <dbReference type="HOGENOM" id="CLU_1247154_0_0_1"/>
    <dbReference type="OMA" id="NINWHRM"/>
    <dbReference type="OrthoDB" id="3355217at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="222" mass="24146" checksum="4B389B8D2EFF5762" modified="2007-05-15" version="1">MGGEDDIKGILGVCAQVCFVGTVIAAARESGAHWLHRTCTLCGGAKTMRCEHCKATGKLQKPEDRGDFATLNAKIETFQCMFCQGKGAVNCRRCAGAGGEIGRNINWHRMVHGEKPFKDLLRNRNFGYIPSLLNERIARQADRDTLDDFHDEVEELDGVAAKIRRFRLSQARGEAPPAKGKRKGKAKKTSSKGKPTNAAAAKNSKPSGKAKKKVAPAPVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6C0</accession>
    <name>A4S6C0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Threonyl/alanyl tRNA synthetase SAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_41622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420915.1">
        <property type="nucleotide sequence ID" value="XM_001420878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6C0"/>
    <dbReference type="STRING" id="436017.A4S6C0"/>
    <dbReference type="GeneID" id="5005027"/>
    <dbReference type="Gramene" id="ABO99208">
        <property type="protein sequence ID" value="ABO99208"/>
        <property type="gene ID" value="OSTLU_41622"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41622"/>
    <dbReference type="eggNOG" id="KOG2105">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_3_1_1"/>
    <dbReference type="OMA" id="ACMEFEG"/>
    <dbReference type="OrthoDB" id="288942at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043039">
        <property type="term" value="P:tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051335">
        <property type="entry name" value="Alanyl-tRNA_Editing_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462">
        <property type="entry name" value="ALANYL-TRNA EDITING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462:SF2">
        <property type="entry name" value="THREONYL AND ALANYL TRNA SYNTHETASE SECOND ADDITIONAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Threonyl/alanyl tRNA synthetase SAD" evidence="3">
        <location>
            <begin position="217"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="269" mass="28152" checksum="0CEFB05DB1AEF936" modified="2007-05-15" version="1">MRATARATATALAHADADAGGTYAFERETTVTRVATRDDGGHEMTLASTIAHPAGGGQPSDSGRVVGANGRAWAFDAATRRRETGEVAHAGRTKPPFEVGDACRVTIDGAKRVLHARIHSAGHALDVAMIRAGLPPTTLTPTKGVHEPALAYVEYKGKVDPEHELADANALMARLNAEMAKLIAEDGASAAAEMTYDEAKAACGGELPAFIAPDMTPRIVTIVPDTPGCPCGGTHVARMSEIQDFKMTGVRVKKGVTRLSYAIPGMATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6F3</accession>
    <name>A4S6F3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421082.1">
        <property type="nucleotide sequence ID" value="XM_001421045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6F3"/>
    <dbReference type="GeneID" id="5005141"/>
    <dbReference type="Gramene" id="ABO99375">
        <property type="protein sequence ID" value="ABO99375"/>
        <property type="gene ID" value="OSTLU_93598"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93598"/>
    <dbReference type="HOGENOM" id="CLU_1393434_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="196" mass="22275" checksum="01D988665A1F4A65" modified="2007-05-15" version="1" fragment="single">VETHDRTHPRTRPDTPLCTQTFYRRLASRTSSDNTASSPRVPRTRPRTPTHRHFSHSRNRSPTVRSTSSRNRSPISRARVRRLVSLRSNWSVGRSFVIGPRPSRTSPYARRIAESTPPLTFAHLFAVAHALTASRVFASYRPSARAPRFKNFSRTRSLCRQCTSAPIDPGARSRGRWQKSSIDRDGMRSGARRGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6I3</accession>
    <name>A4S6I3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Staygreen protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_27130</name>
        <name evidence="9" type="ORF">OSTLU_29779</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the staygreen family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420948.1">
        <property type="nucleotide sequence ID" value="XM_001420911.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422946.1">
        <property type="nucleotide sequence ID" value="XM_001422909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6I3"/>
    <dbReference type="STRING" id="436017.A4S6I3"/>
    <dbReference type="GeneID" id="5004955"/>
    <dbReference type="GeneID" id="5007004"/>
    <dbReference type="Gramene" id="ABO99241">
        <property type="protein sequence ID" value="ABO99241"/>
        <property type="gene ID" value="OSTLU_27130"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01305">
        <property type="protein sequence ID" value="ABP01305"/>
        <property type="gene ID" value="OSTLU_29779"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27130"/>
    <dbReference type="KEGG" id="olu:OSTLU_29779"/>
    <dbReference type="eggNOG" id="ENOG502S3TG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1139355_0_0_1"/>
    <dbReference type="OMA" id="WIRWAAP"/>
    <dbReference type="OrthoDB" id="1931912at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024438">
        <property type="entry name" value="Staygreen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31750:SF4">
        <property type="entry name" value="LP06106P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31750">
        <property type="entry name" value="PROTEIN STAY-GREEN 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12638">
        <property type="entry name" value="Staygreen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Staygreen protein" evidence="7">
        <location>
            <begin position="57"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO99241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP01305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="259" mass="28604" checksum="F12428DA9B0FC9E7" modified="2007-05-15" version="1">MALDRALATRARASGASTSTSTRDASGRRPGPGARGRPAKGRGRGKTTTNAVFDALKFDPDRVSVAFDASSTRVEPESLLQRRYTLTHNDVTRNLTLTVGDAFNDDQTSIWYTRLLRDEVLAEWREDGLHVFCQVSAKEAWWIRWAAPLRSVVFRQKLPLVLDTLRYAERELLATYPELFDSPVYVNFGSADGPGDKEYWGDFRTAGSEETRSSRVTCADGAGLDPRIADNVRNTIITGRGSRVEVGGVILENSPAPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6I8</accession>
    <name>A4S6I8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_17845</name>
        <name evidence="3" type="ORF">OSTLU_19264</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
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                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421375.1">
        <property type="nucleotide sequence ID" value="XM_001421338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S714"/>
    <dbReference type="STRING" id="436017.A4S714"/>
    <dbReference type="GeneID" id="5005379"/>
    <dbReference type="Gramene" id="ABO99668">
        <property type="protein sequence ID" value="ABO99668"/>
        <property type="gene ID" value="OSTLU_27316"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27316"/>
    <dbReference type="HOGENOM" id="CLU_2019085_0_0_1"/>
    <dbReference type="OrthoDB" id="549104at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="13751" checksum="E2392A80986D8B5F" modified="2007-05-15" version="1">MLGLQPTNAAALEVRATNVAALAMYEKCGFETRGSRRGYYADGVDAVCMTRAPGERPVSTRELTRLLAGLDVDAARRPAPPLPERPERVRRAVVDAPRDVAFERASPDDRAFRMRDRVRRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7N1</accession>
    <name>A4S7N1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_43113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPL family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421301.1">
        <property type="nucleotide sequence ID" value="XM_001421264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7N1"/>
    <dbReference type="STRING" id="436017.A4S7N1"/>
    <dbReference type="GeneID" id="5005276"/>
    <dbReference type="Gramene" id="ABO99594">
        <property type="protein sequence ID" value="ABO99594"/>
        <property type="gene ID" value="OSTLU_43113"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43113"/>
    <dbReference type="eggNOG" id="KOG4427">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002173_9_3_1"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="95"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00057703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="443" mass="48833" checksum="3998246129F0A302" modified="2007-05-15" version="1">MELEPAVAASALQSQIDGGAPTQITGLLNDCPHALSFDERVKIFRELIKADRLKAGYRPQAGGADAAHGDTFARPVAQVTLRRESVLEDTLTSVLPLGAKARGRILVKFVNAAGQEEAGIDAGGLFKELLSQVTEQGLDPNRGLFQSNATGLIYPSPRAGDTHEGILLLEMIGMMIGKGMYEGILQDINMAPFFAAHVLGTARTIDDIPSLDEDLARSIVQILEYEGDVADLCLDFTCSEEIYGELVTRELVAGGRDVEVTAANKLFYVFSLADYHLNRRIATPMLAFMRGLTKIINQRWLRLFNVTELSLLLSGGESAIDVDDWELHTRYSGGYSSSSATVRNFWRVMRKFTPKQRQDVLKFVTSSPRPPLQGFKHLNPPFVIHKVRCEASMFAYFGATDVRRLPSASTCFNMLKLPNYRRASTLEKSVSYASQSRAGFELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7T9</accession>
    <name>A4S7T9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_27614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421511.1">
        <property type="nucleotide sequence ID" value="XM_001421474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7T9"/>
    <dbReference type="STRING" id="436017.A4S7T9"/>
    <dbReference type="GeneID" id="5005416"/>
    <dbReference type="Gramene" id="ABO99804">
        <property type="protein sequence ID" value="ABO99804"/>
        <property type="gene ID" value="OSTLU_27614"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27614"/>
    <dbReference type="eggNOG" id="ENOG502QQNF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045644_1_2_1"/>
    <dbReference type="OMA" id="ADHAREY"/>
    <dbReference type="OrthoDB" id="417520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090351">
        <property type="term" value="P:seedling development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238">
        <property type="entry name" value="MEMBRANE BOUND PREDICTED REDOX MODULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="THYLAKOID MEMBRANE PROTEIN TERC, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="283" mass="30302" checksum="8E8BA89BD5939827" modified="2007-05-15" version="1">MTSEAKQNRDVAIVAACLGVSCAFGAGIGAVEGADKASEYFAGYLLEQSLSVDNLFVFVLLFEYFKVPPERQTRVLNYGIVGALVMRAVMVGAGVELIENFQPILLVFAGILIFSSYKLLAEGEEEEEDMGDNAIVKFVGNFLEVSEDYDGDNFFTVQNGVKMATPLLLVLAVVEISDVVFAVDSIPAVFGVTKDPFIVYTSNLFAILSLRQLYTLISKAVGELKYLQTAVALVLGFIGAKMIVEYAGVEVPTEASLAVVVTMLGGGVGASLMLPSEDKEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7W2</accession>
    <name>A4S7W2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="5">5.4.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Glucose phosphomutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">OSTLU_42958</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:68748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:68752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421345.1">
        <property type="nucleotide sequence ID" value="XM_001421308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7W2"/>
    <dbReference type="STRING" id="436017.A4S7W2"/>
    <dbReference type="GeneID" id="5005239"/>
    <dbReference type="Gramene" id="ABO99638">
        <property type="protein sequence ID" value="ABO99638"/>
        <property type="gene ID" value="OSTLU_42958"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42958"/>
    <dbReference type="eggNOG" id="KOG0625">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009330_0_1_1"/>
    <dbReference type="OMA" id="IRERGAY"/>
    <dbReference type="OrthoDB" id="2291at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010319">
        <property type="term" value="C:stromule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009590">
        <property type="term" value="P:detection of gravity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd03085">
        <property type="entry name" value="PGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000002">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000004">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000005">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005737">
        <property type="entry name" value="PRK07564.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573:SF59">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PHOSPHOHEXOMUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24947">
        <property type="entry name" value="PGM1_C_vert_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="19">
        <location>
            <begin position="15"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="20">
        <location>
            <begin position="187"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="21">
        <location>
            <begin position="299"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ABO99638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="558" mass="60366" checksum="03200DD678C2C07C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7W8</accession>
    <name>A4S7W8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP synthase mitochondrial F1 complex assembly factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_43255</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421523.1">
        <property type="nucleotide sequence ID" value="XM_001421486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7W8"/>
    <dbReference type="STRING" id="436017.A4S7W8"/>
    <dbReference type="GeneID" id="5005433"/>
    <dbReference type="Gramene" id="ABO99816">
        <property type="protein sequence ID" value="ABO99816"/>
        <property type="gene ID" value="OSTLU_43255"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43255"/>
    <dbReference type="eggNOG" id="KOG3015">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047893_0_1_1"/>
    <dbReference type="OMA" id="WDPVLHW"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2180.10">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042272">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013:SF10">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07542">
        <property type="entry name" value="ATP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160909">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27085" checksum="43B388C98E21AE79" modified="2007-05-15" version="1">MGADGTAPRFYERVDARERDARDGTWRVELDARALRTPKRNEYAFATEGLARAVAAEWDAQGERIAPFTMPLTSLSATAIDHMGDAETRRVHVETLLKYFGTDATRVRSPDEATAARQAKAHDPIVAWAEREFGPVETSDSIFGPGTSEKTVEVLRRRLHAMCPWELTCAFALSAATKSLLISLKTLRGGLTVDEAIAAARVEEEAQIEEWGLVEGGHDLDQLDIRVKVSAPVVLMKLRRGQKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8E0</accession>
    <name>A4S8E0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS21</name>
        <name evidence="5" type="ORF">OSTLU_27816</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421604.1">
        <property type="nucleotide sequence ID" value="XM_001421567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8E0"/>
    <dbReference type="STRING" id="436017.A4S8E0"/>
    <dbReference type="GeneID" id="5005642"/>
    <dbReference type="Gramene" id="ABO99897">
        <property type="protein sequence ID" value="ABO99897"/>
        <property type="gene ID" value="OSTLU_27816"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27816"/>
    <dbReference type="eggNOG" id="KOG3486">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167122_1_0_1"/>
    <dbReference type="OMA" id="PEGCTIS"/>
    <dbReference type="OrthoDB" id="522601at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1230.20:FF:000008">
        <property type="entry name" value="40S ribosomal protein S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001931">
        <property type="entry name" value="Ribosomal_eS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038579">
        <property type="entry name" value="Ribosomal_eS21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10442">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01249">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002148">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="82" mass="9012" checksum="F68B81D4DEF288D4" modified="2007-05-15" version="1">MINADGENVDLYIPRKCSWTNRLITAKDKASVQLNVGHLDANGVYDGRYTTVALAGYVRSKGESDSAIDLLWQKKKAAINQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8I2</accession>
    <name>A4S8I2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_27860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421771.1">
        <property type="nucleotide sequence ID" value="XM_001421734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8I2"/>
    <dbReference type="STRING" id="436017.A4S8I2"/>
    <dbReference type="GeneID" id="5005736"/>
    <dbReference type="Gramene" id="ABP00065">
        <property type="protein sequence ID" value="ABP00065"/>
        <property type="gene ID" value="OSTLU_27860"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27860"/>
    <dbReference type="eggNOG" id="ENOG502RXAA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_673344_0_0_1"/>
    <dbReference type="OMA" id="REYYWAR"/>
    <dbReference type="OrthoDB" id="498616at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF21">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="409" mass="45818" checksum="9422FEA6F4EA3229" modified="2007-05-15" version="1">MRRRGSATGAVARHARSYARQKPLGACRRQARAREGGTAREEAPRGVSRVDALRHAGATWYEVFKQREARDEIASAFVAGAKIGTRFPRAPGRAARRAWATLKRWRREAPVTPSAALRHAGGSWLDVLTHPEFKTQLGKTLARPFQPVWLRQGAIDAAEARAKAKARDVIDPFGSLRHAGASRFAALTHEKVREYYWARVVAAYVRTVVRHPFSTAMFSSVTKCVSSDIFVQMVLEEKSFFELDWNRVASFFVLGVTYVGAFQYRLYNHWLKPLNDVWRPKYGLALSTGAVVAIDQAFVQPFLYLPTFLGIRVVSEGGTRLLDLPSEIFAKWKQTGPETMTALWLVWVPAQAINFAVVPKHLTIPWMNAIGIAWNGVLSWMTGRYAAAEAAKRKVVDEEVIERGEETAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8S0</accession>
    <name>A4S8S0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Leucine-rich repeat-containing N-terminal plant-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421808.1">
        <property type="nucleotide sequence ID" value="XM_001421771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8S0"/>
    <dbReference type="STRING" id="436017.A4S8S0"/>
    <dbReference type="GeneID" id="5005966"/>
    <dbReference type="Gramene" id="ABP00102">
        <property type="protein sequence ID" value="ABP00102"/>
        <property type="gene ID" value="OSTLU_18438"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18438"/>
    <dbReference type="eggNOG" id="ENOG502QRRF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_544410_0_0_1"/>
    <dbReference type="OMA" id="DCELTRA"/>
    <dbReference type="OrthoDB" id="564617at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="StomDev_PlantInt_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48004:SF59">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING N-TERMINAL PLANT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48004">
        <property type="entry name" value="OS01G0149700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="55513" checksum="D8469A0CB065D390" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S907</accession>
    <name>A4S907_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DMT family transporter: drug/metabolite</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_18490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S907"/>
    <dbReference type="GeneID" id="5005880"/>
    <dbReference type="Gramene" id="ABP00145">
        <property type="protein sequence ID" value="ABP00145"/>
        <property type="gene ID" value="OSTLU_18490"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18490"/>
    <dbReference type="eggNOG" id="ENOG502S191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_22_0_1"/>
    <dbReference type="OMA" id="MYVYRIG"/>
    <dbReference type="OrthoDB" id="2017960at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051258">
        <property type="entry name" value="Diverse_Substrate_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42920:SF5">
        <property type="entry name" value="EAMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42920">
        <property type="entry name" value="OS03G0707200 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="8">
        <location>
            <begin position="144"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="302" mass="31068" checksum="B26D45729B6B1E0F" modified="2007-05-15" version="1">MAYGSLSVSLKLVFESAGAPTAGVLGGVRGLMTILCFAPMLMAKDSKGGEGFETGAGFWRSAAELAFWNLGNQGLCNVALLFTDATRVSFFTQASIAFTPFIASLGGDKVKSMTWLGCALAFCGVAVLGMDGGAAAELGGNFNLGDLLALAGAASYSMYVYRIGQFAKQGFSGQGLQVWKNVFLAAMYGGWMLYDVFAFTSGVPGAAVPWAGWQNLKIWVLLAFTAIVPGCLADLGQAKGQETVSASESSVLLAGEPLFAAVFGAVTLGEILGPMGYVGGALIVFGGLVAGDVFASKKSLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S924</accession>
    <name>A4S924_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CAAX prenyl protease 2/Lysostaphin resistance protein A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_6079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421859.1">
        <property type="nucleotide sequence ID" value="XM_001421822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S924"/>
    <dbReference type="GeneID" id="5005888"/>
    <dbReference type="Gramene" id="ABP00153">
        <property type="protein sequence ID" value="ABP00153"/>
        <property type="gene ID" value="OSTLU_6079"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6079"/>
    <dbReference type="eggNOG" id="ENOG502QR9S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069726_0_0_1"/>
    <dbReference type="OMA" id="LCAPIWE"/>
    <dbReference type="OrthoDB" id="361580at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080120">
        <property type="term" value="P:CAAX-box protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009643">
        <property type="term" value="P:photosynthetic acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592:SF24">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="2">
        <location>
            <begin position="145"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="234" mass="26656" checksum="0215BA75C0AF8962" modified="2007-05-15" version="1" fragment="single">WEAKWGMKVIIQVMVLWFCAFCVIGNAVFPYAAGVLGFDTSSFTQRGLATYSLCLDFTQMLMTWFVLRQSLRPFRPFGVNWFPVRWFEDRKYLRDVAVACVAFPFVVWLHGLSTTLLEHIGLIAFDETVTAAWEQSMKSNDIISKAFYMLLASFAAPVWEELIFRGFFFASLTAFTGAARAMLISSTLFACAHFSLEQFLPLTFLGCLMCVVFVRTRNLLAPVLVHSAWNAWVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S987</accession>
    <name>A4S987_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_18550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422019.1">
        <property type="nucleotide sequence ID" value="XM_001421982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S987"/>
    <dbReference type="GeneID" id="5006059"/>
    <dbReference type="Gramene" id="ABP00313">
        <property type="protein sequence ID" value="ABP00313"/>
        <property type="gene ID" value="OSTLU_18550"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18550"/>
    <dbReference type="HOGENOM" id="CLU_1186665_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="Multiheme cytochromes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="234" mass="27581" checksum="6E2A505C2AC57E0D" modified="2007-05-15" version="1">MTCRACGTDRSVRKYRADLGKYYWRRAHTHMCVKCHEAHVGAMTPEAREEFDKQCAEETGRRKSKALLERREPRPPAPEGMTCRACGTDRNVRKYRADLGKYCWERPHTRMCVKCHEVHLDAMTPEAREEFDKQCAEAAGRRKSKAWMERREPTPPAPEGMTCRACGTDRSVRKYRANLGKYYWHHPYTRMCKKCHKAYLDAMTPRERDEFLHECAEKNREAWTRILRESSPYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S999</accession>
    <name>A4S999_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_93878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422025.1">
        <property type="nucleotide sequence ID" value="XM_001421988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S999"/>
    <dbReference type="GeneID" id="5005929"/>
    <dbReference type="Gramene" id="ABP00319">
        <property type="protein sequence ID" value="ABP00319"/>
        <property type="gene ID" value="OSTLU_93878"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93878"/>
    <dbReference type="HOGENOM" id="CLU_978567_0_0_1"/>
    <dbReference type="OMA" id="ETVETWH"/>
    <dbReference type="OrthoDB" id="497024at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018971">
        <property type="entry name" value="DUF1997"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34131">
        <property type="entry name" value="(RAP ANNOTATION RELEASE2) GALACTOSE-BINDING LIKE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34131:SF3">
        <property type="entry name" value="(RAP ANNOTATION RELEASE2) GALACTOSE-BINDING LIKE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09366">
        <property type="entry name" value="DUF1997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="285" mass="31025" checksum="6B1CF16459F5C9B3" modified="2007-05-15" version="1" fragment="single">VECALDAGEGRDCCAYAVNLRAHTRVRAATDERDEPGLTLSDYMRLPVSQYVDVPLPLGATMARLGEGTVRTATASETRDETFELTIPGLKFFSLEVAPVITVRVRCLGDEETVETWHGRAWDEGVDGEAEVKAGRRPETRRAAMRGPCVLIEIISAKVEGKLVESLGLNDMFVNRGTTAFRWRSIGDGSLDGPALTRTGFVDDEDAASEKESEGACIMGWTDIGVGVDPPGPFAKVPKGVSQRVGDAVLGTTLRVLQSVFVGGLAQDYQRWAYDEEYRSERAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9E5</accession>
    <name>A4S9E5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_37633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421921.1">
        <property type="nucleotide sequence ID" value="XM_001421884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9E5"/>
    <dbReference type="STRING" id="436017.A4S9E5"/>
    <dbReference type="GeneID" id="5006090"/>
    <dbReference type="Gramene" id="ABP00215">
        <property type="protein sequence ID" value="ABP00215"/>
        <property type="gene ID" value="OSTLU_37633"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37633"/>
    <dbReference type="eggNOG" id="KOG2617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025068_0_1_1"/>
    <dbReference type="OMA" id="HWRQQML"/>
    <dbReference type="OrthoDB" id="435022at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000002">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000005">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF4">
        <property type="entry name" value="CITRATE SYNTHASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="544" mass="59148" checksum="AFADC312E06CB183" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9M9</accession>
    <name>A4S9M9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YlxR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422095.1">
        <property type="nucleotide sequence ID" value="XM_001422058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9M9"/>
    <dbReference type="GeneID" id="5006256"/>
    <dbReference type="Gramene" id="ABP00412">
        <property type="protein sequence ID" value="ABP00412"/>
        <property type="gene ID" value="OSTLU_28256"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28256"/>
    <dbReference type="HOGENOM" id="CLU_1268733_0_0_1"/>
    <dbReference type="OrthoDB" id="10610256at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
        <property type="entry name" value="YlxR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037465">
        <property type="entry name" value="YlxR"/>
    </dbReference>
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        <property type="entry name" value="YlxR-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007393">
        <property type="entry name" value="YlxR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215">
        <property type="entry name" value="BLL0784 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215:SF1">
        <property type="entry name" value="YLXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64376">
        <property type="entry name" value="YlxR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="2">
        <location>
            <begin position="100"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23549" checksum="9DBA264B7C159E7E" modified="2007-05-15" version="1">MRRGRTSPKDAGAAVALARVARAAAGDEGDDVRGRADAVERAHAAATTLRTYESAIASAARAQRNRDVAKRKTRPRDRACNQPKPRQGWTRAALRERNARTCAACERIAAKADLFRAVRVKTASGETRVVVGDDARGVNGRSAYVCKTRACAARAAKGKAMQRALRCNVDQGVYDALAREARALEEAMGVDTSDYVFLRPEGTSARWKAPGEWIPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA11</accession>
    <name>A4SA11_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_18758</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422266.1">
        <property type="nucleotide sequence ID" value="XM_001422229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA11"/>
    <dbReference type="GeneID" id="5006218"/>
    <dbReference type="Gramene" id="ABP00583">
        <property type="protein sequence ID" value="ABP00583"/>
        <property type="gene ID" value="OSTLU_18758"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18758"/>
    <dbReference type="HOGENOM" id="CLU_1339168_0_0_1"/>
    <dbReference type="OMA" id="NAWFRSR"/>
    <dbReference type="OrthoDB" id="10465102at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="5">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="8"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="156"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="208" mass="23833" checksum="622B7A451A585BE1" modified="2007-05-15" version="1">MARALDEAKARQTGVSDAGAEILRGVFELERRPDAATRRRLAKQIGTTEQAVNAWFRSRRAKMKRDRLRRVLLVVLLLVGAAGLAFYAWNTFHQTAAAKRRMEALGKNYKWMTRSGLPRPYADKMQRERYGKKKLTYEKEKIITLGGKEDERVVRYTKENPKSSPLTKAPETPRQKLERIRAEASKKASKGRIAPRAQPNTLREPQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA18</accession>
    <name>A4SA18_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422163.1">
        <property type="nucleotide sequence ID" value="XM_001422126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA18"/>
    <dbReference type="GeneID" id="5006327"/>
    <dbReference type="Gramene" id="ABP00480">
        <property type="protein sequence ID" value="ABP00480"/>
        <property type="gene ID" value="OSTLU_28396"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28396"/>
    <dbReference type="HOGENOM" id="CLU_3035769_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="55" mass="5801" checksum="26070EE60F3911ED" modified="2007-05-15" version="1">MAIGKALGATWVSPGMCYPACVNAETLAEMFMIGTPLGVYAMCVGIDSHHGRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAH0</accession>
    <name>A4SAH0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_42298</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422387.1">
        <property type="nucleotide sequence ID" value="XM_001422350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAH0"/>
    <dbReference type="STRING" id="436017.A4SAH0"/>
    <dbReference type="GeneID" id="5006445"/>
    <dbReference type="Gramene" id="ABP00704">
        <property type="protein sequence ID" value="ABP00704"/>
        <property type="gene ID" value="OSTLU_42298"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42298"/>
    <dbReference type="eggNOG" id="KOG2492">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018697_2_1_1"/>
    <dbReference type="OMA" id="CEHFHIP"/>
    <dbReference type="OrthoDB" id="190098at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035597">
        <property type="term" value="F:tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12160:FF:000003">
        <property type="entry name" value="CDK5 regulatory subunit-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000001">
        <property type="entry name" value="tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43020">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43020:SF2">
        <property type="entry name" value="MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00413">
        <property type="entry name" value="CDK5RAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RADICAL_SAM"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="10">
        <location>
            <begin position="67"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="211"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="9">
        <location>
            <begin position="471"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABP00704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="579" mass="63020" checksum="F206332EDD2C0506" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAT0</accession>
    <name>A4SAT0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422491.1">
        <property type="nucleotide sequence ID" value="XM_001422454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAT0"/>
    <dbReference type="GeneID" id="5006549"/>
    <dbReference type="Gramene" id="ABP00808">
        <property type="protein sequence ID" value="ABP00808"/>
        <property type="gene ID" value="OSTLU_29369"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29369"/>
    <dbReference type="HOGENOM" id="CLU_1910172_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="133" mass="14016" checksum="862980A4A98CAE7B" modified="2007-05-15" version="1">MAAMLDQSLDAMIKDAAKATPKRRNAKKSANVKVGGKKNARSAMKKTNAGPTPMAVGGVKKTKNNKKKPARSNAATAMAVDGMMRGGGGRQANAQAGGRTKLVVGNLDFKVNDRDIKVRRRATLAWEGPSVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAY8</accession>
    <name>A4SAY8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_89708</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DECD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422523.1">
        <property type="nucleotide sequence ID" value="XM_001422486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAY8"/>
    <dbReference type="STRING" id="436017.A4SAY8"/>
    <dbReference type="GeneID" id="5006581"/>
    <dbReference type="KEGG" id="olu:OSTLU_89708"/>
    <dbReference type="eggNOG" id="KOG0329">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
    <dbReference type="OMA" id="YAHVEPK"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17950">
        <property type="entry name" value="DEADc_DDX39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000111">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="8"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="209"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABP00840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="358" mass="40064" checksum="65CCBE2741BE4F43" modified="2007-05-15" version="1" fragment="single">LAVQHECIPQAILGMDVLCQAKSGMGKTAVFVITVLQQLDPVPGEVGAVVMCHTRELAYQISHEFERFSTFLGDVTTAVVFGGIPIAQQKEQLKLQPPNIVVATPGRLKALAQDGTLNLKKCAHFVLDECDKMLEAVDMRADVQEIFKMTPHDKQVMMFTATLSKELRALCKKFMNDPMEIFVDDETKLTLHGLVQHYVKLEEAEKNRKLNDLLDSLMFNQVVIFVSSVQRCKALDKLLQECNFPSIAIHGSMGQEERLARYKSFKDGDKRILVATDLVARGIDIERVNIVINYDMPSSADTYLHRVGRAGRFGTKGLAVTFVASSEDTEVLSSVHERFEVEIKELPDEIDQSTYMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB23</accession>
    <name>A4SB23_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422702.1">
        <property type="nucleotide sequence ID" value="XM_001422665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB23"/>
    <dbReference type="GeneID" id="5006759"/>
    <dbReference type="Gramene" id="ABP01019">
        <property type="protein sequence ID" value="ABP01019"/>
        <property type="gene ID" value="OSTLU_94078"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94078"/>
    <dbReference type="eggNOG" id="ENOG502T04W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_326628_0_0_1"/>
    <dbReference type="OMA" id="LHASECT"/>
    <dbReference type="OrthoDB" id="10543195at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="843"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="877"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="884"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="901" mass="97775" checksum="08DA6EAAE2994DB9" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBI2</accession>
    <name>A4SBI2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_19151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422777.1">
        <property type="nucleotide sequence ID" value="XM_001422740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBI2"/>
    <dbReference type="STRING" id="436017.A4SBI2"/>
    <dbReference type="GeneID" id="5006683"/>
    <dbReference type="Gramene" id="ABP01094">
        <property type="protein sequence ID" value="ABP01094"/>
        <property type="gene ID" value="OSTLU_19151"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19151"/>
    <dbReference type="HOGENOM" id="CLU_777049_0_0_1"/>
    <dbReference type="OMA" id="CAGVGAK"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP01094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="357" mass="37433" checksum="C38A93BFC3CE3180" modified="2007-05-15" version="1">MTRATGRARASEDDATTTRGTYGATRTSRGSASDDARDDARRRGTTRARRWRAAGACACLALAIGTCGTGEGGAIERWGEATRALGARAWTKGVGAALGEGSVSSTVTSSVTSTVNGGTPSPPPPSPPPNPPPNPPPPSPPPNPPPNPPPNPPPTATPDAHPSSTPVESPSPAPEPVSSPPALTPDQAAKLKRDIRRLTRKIGRRKPDHPSMPGLQQQLAELQRELNGEASPTSSPSPASEPVSSPPALTPDQAAKLKRDIRRLTRKIGRRKPDHPSMPGLQQQLAELQRELNGEASPTSSVSARLGSKASIVVSTRDLDVSRASLFCVVAVTIVGIVIRRLRRAPEFETDEIARLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBY7</accession>
    <name>A4SBY7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_19266</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422855.1">
        <property type="nucleotide sequence ID" value="XM_001422818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBY7"/>
    <dbReference type="STRING" id="436017.A4SBY7"/>
    <dbReference type="GeneID" id="5007003"/>
    <dbReference type="Gramene" id="ABP01214">
        <property type="protein sequence ID" value="ABP01214"/>
        <property type="gene ID" value="OSTLU_19266"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19266"/>
    <dbReference type="eggNOG" id="KOG0554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_0_1"/>
    <dbReference type="OMA" id="WIISLEK"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000016">
        <property type="entry name" value="Asparagine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003037">
        <property type="entry name" value="PRK03932.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="104"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP01214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="448" mass="50370" checksum="5EF4B683F9643BE4" modified="2007-05-15" version="1">MAFIDLNDGSAISGMQAVVNEGSAAWDALDAGGVSTGAALRVKGKLVASPGGKQAAELAVEEIDVIGTADPETYPLQKKRHTLEYLRSIAHLRPRTNTIGAVARVRNQLAYATHTFFQEHGFLYANTPIITASDCEGAGEQFQVTTLLNGFGAGEWTTPASVVDEQEAMNKDGSIDYSQDFFGKPSYLTVSGQLNGEIMACAVNDIYTFGPTFRAENSNTSRHLAEFWMVEPELAFADLNDDMDCAEAYLKYCLNHVLEHCDEDLEFFEKNISKDNLRERLRNVASQEFARITYTEAVEHVLNAKKKFEFPIEWGSDLQSEHERYISEEVFKDRPVIVRDYPKDIKAFYMRLNDDNKTVAAMDVLVPRVGELMGGSQREERLDVLERRIEEVGLEKESYWWYLDLRRYGSQPHAGFGLGFERLVQYVTGVENIRDAIPFPRYPGSAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQE2</accession>
    <name>A4RQE2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415373.1">
        <property type="nucleotide sequence ID" value="XM_001415336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQE2"/>
    <dbReference type="GeneID" id="4999456"/>
    <dbReference type="Gramene" id="ABO93665">
        <property type="protein sequence ID" value="ABO93665"/>
        <property type="gene ID" value="OSTLU_28633"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28633"/>
    <dbReference type="HOGENOM" id="CLU_1167531_0_0_1"/>
    <dbReference type="OrthoDB" id="10632057at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="238" mass="25145" checksum="8E62909712A57420" modified="2007-05-15" version="1">MARENVFHVEKHANDALHNPPKRGRTHTVREIEAAARALGRATTKDDDGDGDGDGDGVAAGDVVVVDGCVVRVDATRKRSTKTTRARESALATSGALGKGKRRALAEEDRWKTMSRIESGGTAGAAALREARRATLGLSRGVRGERGDDDGPVVVPEGDLRFVDGWAVGRLDGAAEGSETVTGARSLDRSPDGVAVKSKSIDVSFGRAKKKRRDAGRVAETTTTSRRVGGLSFDVEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQM9</accession>
    <name>A4RQM9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_92077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415762.1">
        <property type="nucleotide sequence ID" value="XM_001415725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQM9"/>
    <dbReference type="GeneID" id="4999495"/>
    <dbReference type="Gramene" id="ABO94054">
        <property type="protein sequence ID" value="ABO94054"/>
        <property type="gene ID" value="OSTLU_92077"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92077"/>
    <dbReference type="eggNOG" id="KOG2920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097322_0_0_1"/>
    <dbReference type="OMA" id="PACIARR"/>
    <dbReference type="OrthoDB" id="545599at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF157">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 12 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="215" mass="23387" checksum="FE2379851CAB1A1F" modified="2007-05-15" version="1" fragment="single">VLETEIGNGVGAKLWNAAVTLSERLARTPEIVRGKRVLEVGAGVGMCGILCAKLGAAFVTLSDFEDALLDALDRSVADNGVGDACVARAVDWTKEAERLPTPAANPRHVMPDDAVFDVIIGSDVLYERQHVAALPACVDRRLARDGVCWLVNASRYADMFRDLLAAFDARGFDVDVIEDDLALRRADRESARVKSWHDDGEKTLRCRRRASSPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQN9</accession>
    <name>A4RQN9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_28728</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415767.1">
        <property type="nucleotide sequence ID" value="XM_001415730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQN9"/>
    <dbReference type="GeneID" id="4999930"/>
    <dbReference type="Gramene" id="ABO94059">
        <property type="protein sequence ID" value="ABO94059"/>
        <property type="gene ID" value="OSTLU_28728"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28728"/>
    <dbReference type="HOGENOM" id="CLU_2390061_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020164">
        <property type="entry name" value="Cyt_c_Oxase_assmbl_COX16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14138">
        <property type="entry name" value="COX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="94" mass="10371" checksum="BCB9080E9C19A4F9" modified="2007-05-15" version="1">MSRGGARFFAYGAPFVALVAVGASGLARVVGGRLEVRDALGEVDARAPARTQRVRRAMARFDAEAERRRLIDAREDREAYEMRAVWRPEGGQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQU8</accession>
    <name>A4RQU8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_39729</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQU8"/>
    <dbReference type="STRING" id="436017.A4RQU8"/>
    <dbReference type="GeneID" id="4999472"/>
    <dbReference type="Gramene" id="ABO94087">
        <property type="protein sequence ID" value="ABO94087"/>
        <property type="gene ID" value="OSTLU_39729"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39729"/>
    <dbReference type="eggNOG" id="KOG0032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_0_1"/>
    <dbReference type="OMA" id="SACDMWA"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="273" mass="30694" checksum="A5ED264C45490436" modified="2007-05-15" version="1" fragment="single">MPFLDKYDVLETLGAGGFAVVRKAKHRNTGEIVAVKTLRVEDSDDEDELQSMTLHEVKRELVMMQQLSAHPHIVTIREFFTEQNDEVVHVVMDCLQGEELDDLVNARGAFSEEEVKIIMSAMLDAVAFMHGKGVIHRDLKLENFVLAEKGDLKSLNIVDFGLAKALNARQKAQHVCGTLSYIAPEALLAGVYGQGVDVWALGIAMHVLLTNTWPFDDDDEDELYEQIIECDLDFETEEWESVSDVAKDLIEGLLDPNPKRRLTATQALEHAWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR44</accession>
    <name>A4RR44_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_28885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415835.1">
        <property type="nucleotide sequence ID" value="XM_001415798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR44"/>
    <dbReference type="STRING" id="436017.A4RR44"/>
    <dbReference type="GeneID" id="4999970"/>
    <dbReference type="Gramene" id="ABO94127">
        <property type="protein sequence ID" value="ABO94127"/>
        <property type="gene ID" value="OSTLU_28885"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28885"/>
    <dbReference type="HOGENOM" id="CLU_1430220_0_0_1"/>
    <dbReference type="OMA" id="NHWNDPP"/>
    <dbReference type="OrthoDB" id="498138at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007029">
        <property type="term" value="P:endoplasmic reticulum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040251">
        <property type="entry name" value="SEC31-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923">
        <property type="entry name" value="SEC31-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923:SF11">
        <property type="entry name" value="SECRETORY 31, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="190" mass="20027" checksum="E85D99D29573A0FC" modified="2007-05-15" version="1">MPLVGHPSPAQFAPSAAPQRVVGGVPVSTPSPSASTVTSLRGRERYCSGGAWVGPAPGWPKPPASATIENTDVSRVRQNNLSIVNTLREKYQLAMQGAPPMKLKELEGISNKIGGLFVFLNNTGAAAGADDENTITEPVVEALVTLSDCLASGNTPAVNSILLHLSQKHWEEVSYWFPALKRLARFAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR50</accession>
    <name>A4RR50_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415511.1">
        <property type="nucleotide sequence ID" value="XM_001415474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR50"/>
    <dbReference type="GeneID" id="4999447"/>
    <dbReference type="Gramene" id="ABO93803">
        <property type="protein sequence ID" value="ABO93803"/>
        <property type="gene ID" value="OSTLU_28891"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28891"/>
    <dbReference type="HOGENOM" id="CLU_2945874_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="60" mass="6817" checksum="4DE10BB2E2BE6BAA" modified="2007-05-15" version="1">MKCLISDHFVAKMLDWSSGYDVCLTYTGLRATIWTSTRLRFTSHSYVSQGKRDASRALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRK2</accession>
    <name>A4RRK2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_13873</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415915.1">
        <property type="nucleotide sequence ID" value="XM_001415878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRK2"/>
    <dbReference type="STRING" id="436017.A4RRK2"/>
    <dbReference type="GeneID" id="4999559"/>
    <dbReference type="Gramene" id="ABO94207">
        <property type="protein sequence ID" value="ABO94207"/>
        <property type="gene ID" value="OSTLU_13873"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_13873"/>
    <dbReference type="eggNOG" id="KOG2456">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_3_1_1"/>
    <dbReference type="OMA" id="KMFGDNP"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07087">
        <property type="entry name" value="ALDH_F3-13-14_CALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="10"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="471" mass="51651" checksum="CAB55A0423106E19" modified="2007-05-15" version="1">MRACFAAGLSLPLQKRRQQLMALLKMIREHEAEMLAALREDLSRVGVEALYYDVILPRSEIKAMVNNLRAWTGRRRVWTQRLITWPSSQWTEKQPRGCALVCSSWNFPFMLSLVPLAGAIAAGNTVVLKPSNESAVSTALLVKLLRQYCDPRVVQCVGSEVKGDGIDVMQTVLKEKFDMIFFTGSTTVGKIVARAAAENLTPTVLELGGKNPVVVTDCADLNIAAKQCMWGRTINCGQQCIAPEYVICHESRADRFMELCKTWANRFVPDASVDGAMARIGGPNPASRMAKIGKMLDDAKSGVEGDQIICGGGYDVTRRMVEPTVVKCASEKSPFMNAELFAPILCVLPYKTLGQAVDLIRSKPKPLSMYVFSRTASKTRILIDNTHAGGVTVNGTLTHCAHDGLPFGGVGESGFGRYHGRYSVDCFQREKPVLQKTRGLGFLGFGLITDPPLVYSPPAEWKTRVARMVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRN8</accession>
    <name>A4RRN8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415934.1">
        <property type="nucleotide sequence ID" value="XM_001415897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRN8"/>
    <dbReference type="GeneID" id="4999466"/>
    <dbReference type="Gramene" id="ABO94226">
        <property type="protein sequence ID" value="ABO94226"/>
        <property type="gene ID" value="OSTLU_29084"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29084"/>
    <dbReference type="HOGENOM" id="CLU_1177074_0_0_1"/>
    <dbReference type="OrthoDB" id="10480422at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="236" mass="26802" checksum="8BDA687641038BE7" modified="2007-05-15" version="1">MPAVVTMTRVAGADAAMEMEKTNRQQNALVARMEYHARRATETARALAEARDALECAGKEAKCERERANAATAACQSLRRELGRAQRLNLDSERKARYELERGAKARKALMEMVQDAKKDVKDARGELKASNERARLIEEWAKRRDAAATHAAARLRRMMEDAQALARRLKVVTDENVRLRRRYLRDRAELDDANEYSERLETDWTTRDGAKIVVRNPIFAGACDDADVDVRDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRT3</accession>
    <name>A4RRT3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GS catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_39960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415954.1">
        <property type="nucleotide sequence ID" value="XM_001415917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRT3"/>
    <dbReference type="STRING" id="436017.A4RRT3"/>
    <dbReference type="GeneID" id="4999446"/>
    <dbReference type="Gramene" id="ABO94246">
        <property type="protein sequence ID" value="ABO94246"/>
        <property type="gene ID" value="OSTLU_39960"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39960"/>
    <dbReference type="eggNOG" id="ENOG502QQE3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024307_0_0_1"/>
    <dbReference type="OMA" id="QFLVFCA"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1560">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040577">
        <property type="entry name" value="Gln-synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052725">
        <property type="entry name" value="GS_Type-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022147">
        <property type="entry name" value="GSIII_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42974">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42974:SF1">
        <property type="entry name" value="TYPE-3 GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18318">
        <property type="entry name" value="Gln-synt_C-ter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12437">
        <property type="entry name" value="GSIII_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="3">
        <location>
            <begin position="175"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="688" mass="75119" checksum="FF51D2B2FE2EAA69" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRW4</accession>
    <name>A4RRW4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415973.1">
        <property type="nucleotide sequence ID" value="XM_001415936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRW4"/>
    <dbReference type="GeneID" id="4999894"/>
    <dbReference type="Gramene" id="ABO94265">
        <property type="protein sequence ID" value="ABO94265"/>
        <property type="gene ID" value="OSTLU_29159"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29159"/>
    <dbReference type="HOGENOM" id="CLU_2578187_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="81" mass="9268" checksum="4432645DF39E69F1" modified="2007-05-15" version="1">MSEVRLLRHPRKVGPALVLKLGIRRIGSENSRVRALRMVSLRNALAVFIIRDSPSLIVRHLQKQVTGKRVRLLHARSLLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRY4</accession>
    <name>A4RRY4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_7690</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415985.1">
        <property type="nucleotide sequence ID" value="XM_001415948.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRY4"/>
    <dbReference type="GeneID" id="4999662"/>
    <dbReference type="Gramene" id="ABO94277">
        <property type="protein sequence ID" value="ABO94277"/>
        <property type="gene ID" value="OSTLU_7690"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7690"/>
    <dbReference type="eggNOG" id="KOG2881">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040186_1_2_1"/>
    <dbReference type="OMA" id="AGSNWDD"/>
    <dbReference type="OrthoDB" id="498495at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010270">
        <property type="term" value="P:photosystem II oxygen evolving complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF6">
        <property type="entry name" value="PROTEIN PAM71, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="205" mass="21539" checksum="8298E40E8658A94F" modified="2007-05-15" version="1" fragment="single">FLQGLLLILFSEIGDKTFFIAVLLALQQDKKAVFAGTYGALAAMTVISVTLGQFLHQLDENLPFETSVPWDDFLAAGLLLFFGVQTIRSAEESKAEEEEEDAKEAVEGLGSTFNDEMALIATTAALVFGAEWGDKSFFATIALAAAADPGQVVGGALAGHFIATAGAVTIGDVIGDYISERVVAYAGGSLFILFAVGTLVDAFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS57</accession>
    <name>A4RS57_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_14024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416022.1">
        <property type="nucleotide sequence ID" value="XM_001415985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS57"/>
    <dbReference type="GeneID" id="4999593"/>
    <dbReference type="Gramene" id="ABO94314">
        <property type="protein sequence ID" value="ABO94314"/>
        <property type="gene ID" value="OSTLU_14024"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14024"/>
    <dbReference type="HOGENOM" id="CLU_2309791_0_0_1"/>
    <dbReference type="OMA" id="WRKGAFE"/>
    <dbReference type="OrthoDB" id="425020at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="106" mass="11719" checksum="2CC62799DB3E61E5" modified="2007-05-15" version="1">MPRVKMFIDKTNDACPGKFDFTYNVEEVLRATVPEGQGWYIENNAEKPIPGGESALWRKGAFEVLRLDTDELLYSKKADGSHLVDGKGGPEGKLGKFIEEVMKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSG8</accession>
    <name>A4RSG8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_14344</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416248.1">
        <property type="nucleotide sequence ID" value="XM_001416211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSG8"/>
    <dbReference type="GeneID" id="5000332"/>
    <dbReference type="Gramene" id="ABO94541">
        <property type="protein sequence ID" value="ABO94541"/>
        <property type="gene ID" value="OSTLU_14344"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14344"/>
    <dbReference type="eggNOG" id="KOG0474">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003181_4_1_1"/>
    <dbReference type="OMA" id="RMSMAIC"/>
    <dbReference type="OrthoDB" id="428525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF161">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="10 12" id="KW-0868">Chloride</keyword>
    <keyword evidence="7 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="438"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="524"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="667"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="107"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO94541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="718" mass="76295" checksum="7B85483D95B95E99" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSU8</accession>
    <name>A4RSU8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD-repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Wdr50</name>
        <name evidence="7" type="ORF">OSTLU_119571</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat UTP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416430.1">
        <property type="nucleotide sequence ID" value="XM_001416393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSU8"/>
    <dbReference type="STRING" id="436017.A4RSU8"/>
    <dbReference type="GeneID" id="5000349"/>
    <dbReference type="Gramene" id="ABO94723">
        <property type="protein sequence ID" value="ABO94723"/>
        <property type="gene ID" value="OSTLU_119571"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119571"/>
    <dbReference type="eggNOG" id="KOG2055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_669750_0_0_1"/>
    <dbReference type="OMA" id="FEWTVAC"/>
    <dbReference type="OrthoDB" id="1935146at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045161">
        <property type="entry name" value="Utp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359">
        <property type="entry name" value="WD-REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO94723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="411" mass="44980" checksum="CFFD3177A7FE5310" modified="2007-05-15" version="1">MGGSRGRAWIDDHGDGGFCGNFANKRRVEAVEFAGSELALSQPDEESISFIGSKVVKRWSDGTHTSTGRAFPEVGNSAVRVGLEARRNLNLLDFTRVKDFDFDGPPESAAICVHFHHKRELALSASADSRVNIFRVDGKNNKLFQTLSIENVSIKNVEFSRSSDYTIICGKGNLLLGHLERNTVERVHMRRETLVRGTFAQAPGTDLLGIPGSSEVNIISQTSRTCVMKLNTTGTSVRACVFSHAGMEIIGVTDDGLLYCWDVRMQRCLKKAAGFDDTKCICLTPDGEKIITGQGNGIVSVHRFADVDWSDPYKRRTQSPAKRISSLSTSVTSLSSDPHGDIIIMSSSFKKNALRAFHVPTLSMVKAWPTSSTPLHYVSSTAFNNDGTLLAVANARGRILTYRVCSRQTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTA4</accession>
    <name>A4RTA4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR-repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TPR5</name>
        <name evidence="2" type="ORF">OSTLU_14156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416345.1">
        <property type="nucleotide sequence ID" value="XM_001416308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTA4"/>
    <dbReference type="GeneID" id="5000104"/>
    <dbReference type="Gramene" id="ABO94638">
        <property type="protein sequence ID" value="ABO94638"/>
        <property type="gene ID" value="OSTLU_14156"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14156"/>
    <dbReference type="HOGENOM" id="CLU_444382_0_0_1"/>
    <dbReference type="OMA" id="LANDCAD"/>
    <dbReference type="OrthoDB" id="500452at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="615" mass="67974" checksum="8DDBE8B293484A29" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTF6</accession>
    <name>A4RTF6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416322.1">
        <property type="nucleotide sequence ID" value="XM_001416285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTF6"/>
    <dbReference type="GeneID" id="5000241"/>
    <dbReference type="Gramene" id="ABO94615">
        <property type="protein sequence ID" value="ABO94615"/>
        <property type="gene ID" value="OSTLU_29895"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29895"/>
    <dbReference type="HOGENOM" id="CLU_1273835_0_0_1"/>
    <dbReference type="OMA" id="CATTHAR"/>
    <dbReference type="OrthoDB" id="43442at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007454">
        <property type="entry name" value="UPF0250_YbeD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04359">
        <property type="entry name" value="DUF493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="21576" checksum="A46F9938E5A72803" modified="2007-05-15" version="1">MLAARARSHRTASCATTHARASRVAPARAHRERRARARAVPEGGDDAATPDWAKDLVLDERGDLIDAKTGEPLNEFGATRFDLYVRALRGEYDAPYDTSERDDGEIMETIQQFPAKYTYQVVTTTETASEEGFVSGLVEKIAGAAGEAKVEVEVKPRGKKYSSIWCTMFVFSAKEVSDTIREIKDYDARIKMCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTI0</accession>
    <name>A4RTI0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_36094</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416074.1">
        <property type="nucleotide sequence ID" value="XM_001416037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTI0"/>
    <dbReference type="GeneID" id="5000381"/>
    <dbReference type="Gramene" id="ABO94366">
        <property type="protein sequence ID" value="ABO94366"/>
        <property type="gene ID" value="OSTLU_36094"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36094"/>
    <dbReference type="eggNOG" id="ENOG502S0MX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058969_1_1_1"/>
    <dbReference type="OMA" id="IGVPNKR"/>
    <dbReference type="OrthoDB" id="412320at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF5">
        <property type="entry name" value="PYRUVATE FORMATE-LYASE 1-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PYRUVATE FORMATE-LYASE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01066">
        <property type="entry name" value="organic_radical-activating_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="78"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="324" mass="35891" checksum="09954DED0B1BE6B2" modified="2007-05-15" version="1">MRDDDEKAQPKSPTFCFATKRRGAFPPRPRPIVFLPPERNYAARGLGLLGGDPASAADIEDCGAVTGRVHSIDTFTAVDGHGIRCIVFLQGCEKRCAFCCNVDSTHAALAKTPNPGRTMSVNDIVEILKRNRKYYASSEGGGLTLSGGECLLQPAFVEAVAIKTHEIGLTVAIDTAASGDAETWNRVLPHVDVVLLCVKSSSLEKYKAITGTTEREYETMRAFLKELNRRRVKTWLRFVLMSDPDSRFVDFRTNDENELRGLAELAKTHECVEGIELLPYHRFGEFKFSELGLEYKLEGMRTPDAEEIHAAQTFLQSQGVTVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTY8</accession>
    <name>A4RTY8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CWH43-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_30433</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416868.1">
        <property type="nucleotide sequence ID" value="XM_001416831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTY8"/>
    <dbReference type="GeneID" id="5000925"/>
    <dbReference type="Gramene" id="ABO95161">
        <property type="protein sequence ID" value="ABO95161"/>
        <property type="gene ID" value="OSTLU_30433"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30433"/>
    <dbReference type="HOGENOM" id="CLU_1148839_0_0_1"/>
    <dbReference type="OMA" id="YTRIAAC"/>
    <dbReference type="OrthoDB" id="10432823at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050911">
        <property type="entry name" value="DRAM/TMEM150_Autophagy_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324:SF2">
        <property type="entry name" value="EG:22E5.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324">
        <property type="entry name" value="FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="6">
        <location>
            <begin position="14"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="242" mass="25642" checksum="E015A68788D08F3C" modified="2007-05-15" version="1">MAPGAASGDEISASALVRVACASTVACIVTTYAFATSQSAIATNVFPIISETFTGTPQSAVSEFALGFASWVLFFMVAVVKVYLDRYATSDARWRAHGRRSARVGYVAAICLALTAAINYGESFGAHVTAAFGFLFALWIWLACVVAQLRKHEDAVSRFSMRAKVAGLAFAGLGVGGFTALSALVGKDESRTAYSLIGFCEWLAVLALVAACYTMAWDLDAKGVSIRVCFDEESPPRSEQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTZ5</accession>
    <name>A4RTZ5_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">F-ATPase family transporter: protons (Mitochondrial)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_30441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416872.1">
        <property type="nucleotide sequence ID" value="XM_001416835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTZ5"/>
    <dbReference type="STRING" id="436017.A4RTZ5"/>
    <dbReference type="GeneID" id="5001058"/>
    <dbReference type="Gramene" id="ABO95165">
        <property type="protein sequence ID" value="ABO95165"/>
        <property type="gene ID" value="OSTLU_30441"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30441"/>
    <dbReference type="eggNOG" id="KOG1353">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_415839_0_0_1"/>
    <dbReference type="OMA" id="RPMVEEF"/>
    <dbReference type="OrthoDB" id="30023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="entry name" value="ATP synthase alpha/beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="4">
        <location>
            <begin position="140"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase alpha subunit C-terminal" evidence="5">
        <location>
            <begin position="453"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO95165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="565" mass="60365" checksum="2EC43C9B79571DBB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTZ6</accession>
    <name>A4RTZ6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_6857</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416581.1">
        <property type="nucleotide sequence ID" value="XM_001416544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTZ6"/>
    <dbReference type="STRING" id="436017.A4RTZ6"/>
    <dbReference type="GeneID" id="5000713"/>
    <dbReference type="Gramene" id="ABO94874">
        <property type="protein sequence ID" value="ABO94874"/>
        <property type="gene ID" value="OSTLU_6857"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6857"/>
    <dbReference type="eggNOG" id="KOG2249">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022453_3_1_1"/>
    <dbReference type="OMA" id="TSEYKHF"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06144">
        <property type="entry name" value="REX4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000007">
        <property type="entry name" value="Interferon-stimulated exonuclease gene 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037431">
        <property type="entry name" value="REX4_DEDDh_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="10">
        <location>
            <begin position="3"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="20257" checksum="D0B82217FF3374EF" modified="2007-05-15" version="1" fragment="single">VTAVLALDCEMVGVGADGKRSILARASIVNEDGNVIMDAHVLPTERVTDYRTAVSGVRAKDLTAANGAVAFKKVQAQMSELLRGRILVGHSLKNDMRVLMLDHPKRDTRDTSLYHPLTRPLRPEERCVPGAPRGRGCRALRDLARQHLGLEIQKGEHSSVDDARATLALYKKFAKRWESALRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU16</accession>
    <name>A4RU16_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="1">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_45116</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
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        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis.</text>
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    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416881.1">
        <property type="nucleotide sequence ID" value="XM_001416844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU16"/>
    <dbReference type="STRING" id="436017.A4RU16"/>
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    <dbReference type="Gramene" id="ABO95174">
        <property type="protein sequence ID" value="ABO95174"/>
        <property type="gene ID" value="OSTLU_45116"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_45116"/>
    <dbReference type="eggNOG" id="KOG0571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014658_2_2_1"/>
    <dbReference type="OMA" id="QFASKHT"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
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        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006949">
        <property type="entry name" value="PRK09431.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="10">
        <location>
            <begin position="2"/>
            <end position="193"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="638" mass="71792" checksum="E5397AAFC3C89A79" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUE0</accession>
    <name>A4RUE0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416906.1"/>
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    <dbReference type="AlphaFoldDB" id="A4RUE0"/>
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    <dbReference type="Gramene" id="ABO95236">
        <property type="protein sequence ID" value="ABO95236"/>
        <property type="gene ID" value="OSTLU_14602"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14602"/>
    <dbReference type="HOGENOM" id="CLU_500040_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="545" mass="59781" checksum="5002477F4276935F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUG0</accession>
    <name>A4RUG0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_30607</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416953.1">
        <property type="nucleotide sequence ID" value="XM_001416916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUG0"/>
    <dbReference type="STRING" id="436017.A4RUG0"/>
    <dbReference type="GeneID" id="5001023"/>
    <dbReference type="Gramene" id="ABO95246">
        <property type="protein sequence ID" value="ABO95246"/>
        <property type="gene ID" value="OSTLU_30607"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30607"/>
    <dbReference type="eggNOG" id="KOG2543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028223_1_0_1"/>
    <dbReference type="OMA" id="QLRRWHG"/>
    <dbReference type="OrthoDB" id="365981at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020796">
        <property type="entry name" value="ORC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047088">
        <property type="entry name" value="ORC5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048866">
        <property type="entry name" value="ORC5_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14630">
        <property type="entry name" value="ORC5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21639">
        <property type="entry name" value="ORC5_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="ORC5 lid" evidence="10">
        <location>
            <begin position="181"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 5 C-terminal" evidence="9">
        <location>
            <begin position="307"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO95246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="459" mass="50929" checksum="35636C68852141CC" modified="2007-05-15" version="1">MYVHGPPVTGKTSIVRDVVGRSGRPWAYASCATEHAPKLLYEAVVEELTPYLVRSSESLRRASAEQVKKALKCDRFSDLVEILRAHLPASPGARACYVVVDEAQRMLQWRGEPVLNAFLRLAELSCRKVIVIFIGEQGWDTFCSASGTTPYEGVYFPAYSREELRYILLKERPSDADEMLYNGFLGVMLNTFTATCRNLHELRATVAPLWAQYVKPYEEARARGDPLPEPRALYAALNSKKGSTKGDECANARDGGSSSAPKREQPNVHTGLTVPLSPAALALGRGEWPVRRDATGSGAGGRLDFEIPRLTKFLLVAAFLCSHNSDEVDKRMFGGQIEGHVARAKRKDRNAQDRERAAAAEAAVDKRRVFKLERLIAWFHFITRSACDEHGAEVADLEEELLSADVFMQISSMTQLGMLSINRGSAMEGGLYQCNISRDLAERLAQNLGVHLDTYLKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUJ4</accession>
    <name>A4RUJ4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_30642</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>coproporphyrinogen III + O2 + 2 H(+) = protoporphyrinogen IX + 2 CO2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:18257"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="1.3.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416682.1">
        <property type="nucleotide sequence ID" value="XM_001416645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUJ4"/>
    <dbReference type="STRING" id="436017.A4RUJ4"/>
    <dbReference type="GeneID" id="5000783"/>
    <dbReference type="Gramene" id="ABO94975">
        <property type="protein sequence ID" value="ABO94975"/>
        <property type="gene ID" value="OSTLU_30642"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30642"/>
    <dbReference type="eggNOG" id="KOG1518">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026169_0_0_1"/>
    <dbReference type="OMA" id="VHANWRY"/>
    <dbReference type="OrthoDB" id="15318at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1500.10:FF:000002">
        <property type="entry name" value="oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018375">
        <property type="entry name" value="Coprogen_oxidase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01021">
        <property type="entry name" value="COPROGEN_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO94975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="368" mass="40876" checksum="CD724525459760A1" modified="2007-05-15" version="1">MRATGVDKPRAVRASAVRARATRGGATRARAAAQGIEQEVKIDAAPTTLLREGSGEEGDATQMRARFEKMIRAAQNEICDAITALDGKPFHEDAWTRPGGGGGISRVLQDGNVFEKAGVNVSVVYGQMPPEAYRAATGEEGASKEMIPFFAAGISSVMHPHNPMAPTVHFNYRYFETDAPKGSAGAPRAWWFGGGTDLTPSYIFDEDVTHFHQTLKDICDKHDGEFYPKFKQWADDYFMIKHRGERRGVGGVFFDDMNDRSKDELLAFATDMAGGVVPAYVPLVAKHKDDEFTPEQRAWQQMRRGRYVEFNLVYDRGTTFGLKTGGRIESILMSLPRYCEWQYDHAPEAGSREADALDAFKNPRTWCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="108" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUQ7</accession>
    <name>A4RUQ7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_30705</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416713.1">
        <property type="nucleotide sequence ID" value="XM_001416676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUQ7"/>
    <dbReference type="STRING" id="436017.A4RUQ7"/>
    <dbReference type="GeneID" id="5000582"/>
    <dbReference type="Gramene" id="ABO95006">
        <property type="protein sequence ID" value="ABO95006"/>
        <property type="gene ID" value="OSTLU_30705"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30705"/>
    <dbReference type="eggNOG" id="KOG0018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_0_1_1"/>
    <dbReference type="OMA" id="KHMDFQR"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03275">
        <property type="entry name" value="ABC_SMC1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028468">
        <property type="entry name" value="Smc1_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF12">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="13">
        <location>
            <begin position="521"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="326"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="416"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="673"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="802"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1225" mass="138968" checksum="121A52CF6F4085BA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUS1</accession>
    <name>A4RUS1_OSTLU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUS1"/>
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    <dbReference type="Gramene" id="ABO95013">
        <property type="protein sequence ID" value="ABO95013"/>
        <property type="gene ID" value="OSTLU_30719"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30719"/>
    <dbReference type="HOGENOM" id="CLU_2150093_0_0_1"/>
    <dbReference type="OrthoDB" id="497467at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="112" mass="11874" checksum="5C601ED0904F9BB8" modified="2007-05-15" version="1">MRTIARVAGVANARRVATPRQRARRAASTVATRAKEANAASETVDDVALGMEPCLVGWADKDANGADVYCCEQPGGEVACQVADTTEKVECAIIEDEETGEMTVDCSKIERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUT7</accession>
    <name>A4RUT7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>Mamiellophyceae</taxon>
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            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416729.1">
        <property type="nucleotide sequence ID" value="XM_001416692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUT7"/>
    <dbReference type="ESTHER" id="ostlu-a4rut7">
        <property type="family name" value="Fusarinine_C_esterase_sidJ"/>
    </dbReference>
    <dbReference type="GeneID" id="5000706"/>
    <dbReference type="Gramene" id="ABO95022">
        <property type="protein sequence ID" value="ABO95022"/>
        <property type="gene ID" value="OSTLU_30735"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30735"/>
    <dbReference type="eggNOG" id="KOG4840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049633_4_0_1"/>
    <dbReference type="OMA" id="ALQPTEW"/>
    <dbReference type="OrthoDB" id="10034502at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
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        <property type="entry name" value="SidJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591:SF1">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08538">
        <property type="entry name" value="DUF1749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30299" checksum="3FAC1F088BC0AD76" modified="2007-05-15" version="1">MYADGCASSEARACVVVVPGLGDGPASLSYVARGSALEARCASTARALIRFELSTSYEGYGTRRLRDDARDIDAVIRALRVKFPLATSFALVGHSTGCQSICHYLASGYDSASAVDRIVLQAGVSDRDWYDADCGREVMREWVARAREMAPDDLMPADTPGTYGVATNARRFLSLASAGGDDDWFSLDIFDGSSGEGVESSKIVRKLGAGACARVDVRLVVSTADEYVPYDRDVVVAHNERIRDAFARVAKSARTHYIEANHDLSDMAEKDAPGFVDFVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV59</accession>
    <name>A4RV59_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TFIIE beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_14806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416785.1">
        <property type="nucleotide sequence ID" value="XM_001416748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV59"/>
    <dbReference type="STRING" id="436017.A4RV59"/>
    <dbReference type="GeneID" id="5000747"/>
    <dbReference type="Gramene" id="ABO95078">
        <property type="protein sequence ID" value="ABO95078"/>
        <property type="gene ID" value="OSTLU_14806"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14806"/>
    <dbReference type="eggNOG" id="KOG3095">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_967536_0_0_1"/>
    <dbReference type="OMA" id="LARFWLQ"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TFIIE beta" evidence="1">
        <location>
            <begin position="75"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="296" mass="32999" checksum="E6717DF1F1242BCB" modified="2007-05-15" version="1">MAGSSKRKASVLEKTLNKYRSGQKAASKIMTAAARDRAALDARSEAQYARMKAAAEAQKLAEAAAIAAMEAEAKPVEPVKVVATNLLAKQKHAIDTLFAQRRPMSNDDLRVFLGFDCNVGPLFESLKNHEKVRYDAAKGLFEYRAKHDVLCKEDVLELVNSTPDGLAIDEIVDAYVKAKDDAIALAEEDDAVIMLTNTETKKKVLFRKQPEYEVDLSEDFVGSFHDIEIPEYDVDFDKALRREGIEPTPRPVYDLGPAPEVEKKKKKRAVNFERMNVTNAHMPELFKAAQVDRLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RVT2</accession>
    <name>A4RVT2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31087</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RVT2"/>
    <dbReference type="GeneID" id="5001402"/>
    <dbReference type="Gramene" id="ABO95497">
        <property type="protein sequence ID" value="ABO95497"/>
        <property type="gene ID" value="OSTLU_31087"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31087"/>
    <dbReference type="eggNOG" id="ENOG502S43J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169286_0_0_1"/>
    <dbReference type="OMA" id="RVEKYGH"/>
    <dbReference type="OrthoDB" id="532630at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO95497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="79" mass="9220" checksum="E806F0CE79C27B5E" modified="2007-05-15" version="1">MHPPLTLDKHPICREAVIALKRCHAENALGKFLGKCNEEKWTLDACLKEQKLWKSRRNLKLARESKARLAKKLEEERAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWF3</accession>
    <name>A4RWF3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="11">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_31319</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 11">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Glycosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="11"/>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417568.1">
        <property type="nucleotide sequence ID" value="XM_001417531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWF3"/>
    <dbReference type="STRING" id="436017.A4RWF3"/>
    <dbReference type="GeneID" id="5001519"/>
    <dbReference type="Gramene" id="ABO95861">
        <property type="protein sequence ID" value="ABO95861"/>
        <property type="gene ID" value="OSTLU_31319"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31319"/>
    <dbReference type="eggNOG" id="KOG2711">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033449_0_2_1"/>
    <dbReference type="OMA" id="NIYTPIA"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020015">
        <property type="term" value="C:glycosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045017">
        <property type="term" value="P:glycerolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="term" value="P:systemic acquired resistance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(P)+]"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(P)+]"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000940">
        <property type="entry name" value="PRK00094.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000942">
        <property type="entry name" value="PRK00094.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF1">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)] 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0327">Glycosome</keyword>
    <keyword evidence="3 9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="2 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="12">
        <location>
            <begin position="23"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="13">
        <location>
            <begin position="201"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="28"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="276"/>
            <end position="277"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00084116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO95861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="353" mass="37255" checksum="A8D30F0BF97BE840" modified="2007-05-15" version="1">MRWAAFVESAHANDESVLQSSKKVAIMGGGSFGTAMATLLARNKADLDVVILMRNEDDARALNEEHRNVKYLPKYSLPVNIRASTDAKEALAGCDFIIHAVPVQQSRKFLAGVKDYIDPKTPMLCLSKGLETGTCDMMSEIIPSGLGRDQPLAVLSGPTFAVELMQGLPTTIVAASEDESLAISVQQLFGSSCLRVNTSTDVTGVELSGAMKNVLAIAAGIVEGLELGNNAMAALVAQGVAEIRWLAGKMGARPETLAGVSGTGDIMLTCFVNLSRNRTVGVRLGSGETLEEVLGSMNQVAEGVATAAAVVQLAKRYRVHLPVLTAVASILDGHMDAKTAVDKIMHLPQVPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWJ2</accession>
    <name>A4RWJ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_5313</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417587.1">
        <property type="nucleotide sequence ID" value="XM_001417550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWJ2"/>
    <dbReference type="STRING" id="436017.A4RWJ2"/>
    <dbReference type="GeneID" id="5001425"/>
    <dbReference type="Gramene" id="ABO95880">
        <property type="protein sequence ID" value="ABO95880"/>
        <property type="gene ID" value="OSTLU_5313"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5313"/>
    <dbReference type="eggNOG" id="KOG0773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040111_0_2_1"/>
    <dbReference type="OMA" id="HSDDMMG"/>
    <dbReference type="OrthoDB" id="496851at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005539">
        <property type="entry name" value="ELK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005540">
        <property type="entry name" value="KNOX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03789">
        <property type="entry name" value="ELK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03790">
        <property type="entry name" value="KNOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01188">
        <property type="entry name" value="ELK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01255">
        <property type="entry name" value="KNOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="183"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO95880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="244" mass="28328" checksum="0FDC4FC8A533F9C0" modified="2007-05-15" version="1" fragment="single">SATDSEEMTLAVRAHPMYPRLVEAYYECRQIGAEGDVLEALDRERDAMLYSVQVMNEDASSSGGAHDVPQRDLDRFMRECTHELESYVKELHALYEDAKSCCRELETRARKVRSDVVKSADIRGEAAESKRRAPATAAEHAAASGDFDQILSNSQQRRDHEERLREALKRKYASSIMTLKSEFMRKRKKGKLPDQSTEVLKNWWSENIVWPYPTEDDKRELIAQTKLDATQVNNWFINFRKRHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWV2</accession>
    <name>A4RWV2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CST complex subunit CTC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_31468</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417888.1">
        <property type="nucleotide sequence ID" value="XM_001417851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWV2"/>
    <dbReference type="GeneID" id="5002054"/>
    <dbReference type="Gramene" id="ABO96181">
        <property type="protein sequence ID" value="ABO96181"/>
        <property type="gene ID" value="OSTLU_31468"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31468"/>
    <dbReference type="HOGENOM" id="CLU_278912_0_0_1"/>
    <dbReference type="OMA" id="ITIHRAM"/>
    <dbReference type="OrthoDB" id="2314520at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045740">
        <property type="term" value="P:positive regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010833">
        <property type="term" value="P:telomere maintenance via telomere lengthening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042617">
        <property type="entry name" value="CTC1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14865">
        <property type="entry name" value="CST COMPLEX SUBUNIT CTC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14865:SF2">
        <property type="entry name" value="CST COMPLEX SUBUNIT CTC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0779">Telomere</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1132" mass="124213" checksum="3EF12E3D94EA67C2" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWW1</accession>
    <name>A4RWW1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF445 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_15260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417892.1">
        <property type="nucleotide sequence ID" value="XM_001417855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWW1"/>
    <dbReference type="GeneID" id="5002059"/>
    <dbReference type="Gramene" id="ABO96185">
        <property type="protein sequence ID" value="ABO96185"/>
        <property type="gene ID" value="OSTLU_15260"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15260"/>
    <dbReference type="eggNOG" id="ENOG502RMTT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028773_0_0_1"/>
    <dbReference type="OMA" id="PFFAAIW"/>
    <dbReference type="OrthoDB" id="410754at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35791">
        <property type="entry name" value="UPF0754 MEMBRANE PROTEIN YHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35791:SF1">
        <property type="entry name" value="UPF0754 MEMBRANE PROTEIN YHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52221" checksum="7E55D4B531DD99FE" modified="2007-05-15" version="1">MEIRNNWRLLSIQKRTKAFERRMFNSMDSLRGKLSAVLSNKVIARAVDKFNADRKGMLLIPLVAAFVGWFTNWLAVKMIFYPINFLGIPLFQYVEGSVYGFDILQPLGILGWQGIVPAKAAQMSLTMVTMVTEKLVNVQAVFMLLDPTAVSSLLLTEVPNMASKIASEMIPDWSLKLAESAVPALPTPTLGEVGGVVSTYLSGFVTLLQQQVDHVIDLKELVVTAMCTDRVVLVDLFRRCGAAELDFLVNSGLFFGFLLGVIQMVVWAFYDNPWSITIGGMIVGLLTNWLALKCIFEPVEPVFVGPFKIQGLFLQRQHEVSGTFSDYLTEKVLKSENIWNNMLNGDKGPEFNAMLEQYTKKFVVEEAAARGMSVADLDVSLIDEVCRKVVEKLPEHIHVLHEYTDATLGLKELMRERMKLMTPQEFERVLHPIFEQDELTLIISGAVLGAAAGYIQQIYSVKPPADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX37</accession>
    <name>A4RX37_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_87197</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO95981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417688.1">
        <property type="nucleotide sequence ID" value="XM_001417651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX37"/>
    <dbReference type="GeneID" id="5001689"/>
    <dbReference type="Gramene" id="ABO95981">
        <property type="protein sequence ID" value="ABO95981"/>
        <property type="gene ID" value="OSTLU_87197"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87197"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030929_0_0_1"/>
    <dbReference type="OMA" id="CIANFAI"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF46">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="490" mass="51162" checksum="902EEABD6DC53D1E" modified="2007-05-15" version="1">MAGDASEGAARGDAGAAWLSEDATPRNDALDKLIISLFVPAMLNFLIIPLVGAVDVFWVGRLEDAVALAAQGAANQVFQSAFWIISFIPSVVAPVVAKAAAGGDTNELSKKIGEGIFCAAVVGAMGMVLMYTMQERALGIVGVAAGSVTAHQAAPYVGYRALTFIPAIVSTVGFAAFRGTLDVMTPMKITLASQMLNVVLDPLFIFGVGTFKAMGVAGAAIATSISEIFSAGLYTTLLVKRKLVDLKDMFRPPSAAALGTLLVGGAGVQLRAVAQNITFLAVMRAILTMDSTGTAAAAHTISSQVFQLGVIAILALSTIATILIPQRMNSMEKGGPREAKRVADRLLVWGVVIGVILAVLQAGAIPFLGVFSSLSEVQEQAKMPCIIGALLQPLNGIVFVGEGLMQGHQAFLRLAAGMFVSTGAMLVALNIYGNSLAGVWFCFTVFNTFRLFFGLRHHFFDGPLAPRHIDATIAKLEVETAAKAAAAKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX79</accession>
    <name>A4RX79_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aspartate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31597</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417950.1">
        <property type="nucleotide sequence ID" value="XM_001417913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX79"/>
    <dbReference type="STRING" id="436017.A4RX79"/>
    <dbReference type="GeneID" id="5001814"/>
    <dbReference type="Gramene" id="ABO96243">
        <property type="protein sequence ID" value="ABO96243"/>
        <property type="gene ID" value="OSTLU_31597"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31597"/>
    <dbReference type="eggNOG" id="KOG1411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032440_1_2_1"/>
    <dbReference type="OMA" id="GTWTHIT"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000015">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF54">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="29"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="399" mass="44300" checksum="BE9FFDC2383C8891" modified="2007-05-15" version="1">MSRFGDVPEAPKDPILGISEMFNADAHAEKMNLGVGAYRDDNGKPVVLNCVREAEKRIAGNFNMEYLPTNGSKDFVQQSLKLAFGENSAHVADGSIAAVQSLSGTGSCRLMAEFQRRFMPGCKVYITVPTWSNHHNIWRDAGCEQDTFRYYKESTRGLDFEGMVEDIQNAPDGSMFLLHACAHNPTGVDPSAEQWREISKVMKAKNHFAFFDMAYQGFASGDCERDAQAIRIFVEDGHKVALAQSFAKNMGLYGQRIGTVSVMCKDKEEANRVESQLKVIARAMYSNPPMHGALIASTILGDAALKAQWYEEVKGMADRIIKMRTLLRKNLEESGSTLPWQHVTDQIGMFCFSGMTGEQVDKLRTDHHIYMTRNGRISMAGVTSSNVGRLAAAMHEVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXC3</accession>
    <name>A4RXC3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_24535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417975.1">
        <property type="nucleotide sequence ID" value="XM_001417938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXC3"/>
    <dbReference type="STRING" id="436017.A4RXC3"/>
    <dbReference type="GeneID" id="5001848"/>
    <dbReference type="Gramene" id="ABO96268">
        <property type="protein sequence ID" value="ABO96268"/>
        <property type="gene ID" value="OSTLU_24535"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24535"/>
    <dbReference type="eggNOG" id="KOG2617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022049_2_1_1"/>
    <dbReference type="OMA" id="YTVIFGI"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO96268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="399" mass="43785" checksum="DB55713BB2EA7D6D" modified="2007-05-15" version="1">MVAGGMRGITAMLYETSLLDAEEGIRFRGRAIPELREKLPKARGGEEPLPEGIMWLMLTGEIPSEAQVRTLSAELAARAEVPKAVFDALDALPKNAHPMTQLSVALMAMQPESKFAKAYQDGAHKTTFWEHAFEDSMDIIARLPAVCAAIYRRTFKDGTLVAADASLDWAANFAHMMGHDSEAVKELMRLYMTIHVDHEGGNVSAHATHLVGSALSDPYLSLVAGLNGLAGPLHGLANQEVLKWLNETREKVGDNATKEELTEFVWATLKSGRVVPGYGHGVLRKTDPRYTCQREFALKHLPDDPMFKLVGKLFEVVPGVLTETGKVKNPWPNVDAHSGVLLQYYGITEANFYTVLFGASRAIGVLSQLTLSRGSGYPIERPKSVTSQWIEEKFGKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXQ1</accession>
    <name>A4RXQ1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_92764</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417796.1">
        <property type="nucleotide sequence ID" value="XM_001417759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXQ1"/>
    <dbReference type="GeneID" id="5001890"/>
    <dbReference type="Gramene" id="ABO96089">
        <property type="protein sequence ID" value="ABO96089"/>
        <property type="gene ID" value="OSTLU_92764"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92764"/>
    <dbReference type="HOGENOM" id="CLU_063545_0_0_1"/>
    <dbReference type="OMA" id="AGECAPM"/>
    <dbReference type="OrthoDB" id="271506at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="277"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="333" mass="35824" checksum="7111813903A15360" modified="2007-05-15" version="1">MPSFTPSTSDAAGCLTALEDVSPSLRVLGAMSFVVSALIGAPQAYKIYARKSSRGVSFWTLALGNVGGFLCVLNLYVLHYDQIKLSGNAFADFKGWARGQPSLLFIWVELANTLSMLIVTPMAYAYVEDSEHAFAVTTPLGGVDWSMKKAVRAGVLLQMVIVACAWAPALIVLHRAGECAPMAWYGNAIGVVVAMIICLKFIPQVKESYENKGSGSLSYLTYGADLCGGLVAFLQKLLVTNERVSTWLPPLILHSLEAYVLGMNAINDKARLGAGAARRDRDADDANEPDEERVQSERLLPRASRGASGATSPRASSPTRADAASWWKSATWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXV8</accession>
    <name>A4RXV8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_31834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418064.1">
        <property type="nucleotide sequence ID" value="XM_001418027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXV8"/>
    <dbReference type="STRING" id="436017.A4RXV8"/>
    <dbReference type="GeneID" id="5002147"/>
    <dbReference type="Gramene" id="ABO96357">
        <property type="protein sequence ID" value="ABO96357"/>
        <property type="gene ID" value="OSTLU_31834"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31834"/>
    <dbReference type="eggNOG" id="KOG0550">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_381031_0_0_1"/>
    <dbReference type="OMA" id="NICACEQ"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052758">
        <property type="entry name" value="SRC_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44200">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44200:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="619"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="727" mass="80910" checksum="5B2E26B4AB6E6674" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYQ4</accession>
    <name>A4RYQ4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_41053</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="12">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418433.1">
        <property type="nucleotide sequence ID" value="XM_001418396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYQ4"/>
    <dbReference type="STRING" id="436017.A4RYQ4"/>
    <dbReference type="GeneID" id="5002226"/>
    <dbReference type="Gramene" id="ABO96726">
        <property type="protein sequence ID" value="ABO96726"/>
        <property type="gene ID" value="OSTLU_41053"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41053"/>
    <dbReference type="eggNOG" id="KOG3111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054856_0_1_1"/>
    <dbReference type="OMA" id="CHLMIED"/>
    <dbReference type="OrthoDB" id="1927044at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000171">
        <property type="entry name" value="Ribulose-phosphate 3-epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="154"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="205"/>
            <end position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="231" mass="24864" checksum="8C081ED33D234388" modified="2007-05-15" version="1">MSTPYANAPVISPSLLSCDFARMADESRKVIACGADWLHLDVMDGHFVPNLTFGAPVLTSLRPHVPDAYFDVHLMVTNPLDYIEPMAKAKTNMFTFHAEACDGDAGVERACEEVRKAGMEVGIAIKPGTAVDVVHSSVEKGLCDMVLVMTVEPGFGGQKFNPECCEKVKRLRERFPKLKIQVDGGLSASTIDAAAEAGANVIVAGSSVFGSDDWTKAIDVLREGVQKYNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ21</accession>
    <name>A4RZ21_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine phosphatase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418498.1">
        <property type="nucleotide sequence ID" value="XM_001418461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ21"/>
    <dbReference type="GeneID" id="5002274"/>
    <dbReference type="Gramene" id="ABO96791">
        <property type="protein sequence ID" value="ABO96791"/>
        <property type="gene ID" value="OSTLU_92911"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92911"/>
    <dbReference type="eggNOG" id="KOG4754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073762_0_0_1"/>
    <dbReference type="OMA" id="ERWWYLP"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF57">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="31049" checksum="71EB2EB6E38FB64C" modified="2007-05-15" version="1">MRWIAVAASGTPELGNVSMSTFAKRKRASAKAPARGDAKTIHLVRHGRTEMNDYLRENHWADPDFVDPMMIDTRLTSEGEAQARALRTIATALEPAPELIVASPLRRALRTAELAFGAAGEDALGDVPRVVCALARERVFHGSDIGRVARELGEDHPDWDLTEMGDDDATWWYTPDGKDPFTTAELEPVDVFEERMQEFRRWLDARPEKSIAVIAHWGVCYSLTGDEFQNCELRTLDFHTDLDVGNGDFQKFDVFLQDNIWGQIGRALVSFKNKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZ90</accession>
    <name>A4RZ90_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_5143</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418289.1">
        <property type="nucleotide sequence ID" value="XM_001418252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZ90"/>
    <dbReference type="STRING" id="436017.A4RZ90"/>
    <dbReference type="GeneID" id="5002424"/>
    <dbReference type="Gramene" id="ABO96582">
        <property type="protein sequence ID" value="ABO96582"/>
        <property type="gene ID" value="OSTLU_5143"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5143"/>
    <dbReference type="eggNOG" id="KOG2512">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032612_2_0_1"/>
    <dbReference type="OMA" id="YFQHEIT"/>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1250">
        <property type="entry name" value="Tubulin Binding Cofactor C, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038397">
        <property type="entry name" value="TBCC_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="5">
        <location>
            <begin position="78"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="255" mass="28722" checksum="51B1EB9BC6D6D168" modified="2007-05-15" version="1" fragment="single">KAALRAVNARVVDLDRATAEWSYFLPAYDARVMMRKMGELREQFERAVACVTPRERFRFKSRGGRATVGGAAASAATPANQTAVAMAALDLCDADDGPGTRDRRGETIVIDRATNDGEDYALERLVDCDIFVLGAIRALRAYDLRRCRVYVLAIAGSALVENIVDSVVCVATRQLRVHAARRTNFHVRATSRPIVEDSREVAFAPRFSIESPNEEEVLKAHGLFEENHMWREVDDFLWLKSSQSPHWRLLDERDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="115" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZD8</accession>
    <name>A4RZD8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">TrmE-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_49818</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418313.1">
        <property type="nucleotide sequence ID" value="XM_001418276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZD8"/>
    <dbReference type="STRING" id="436017.A4RZD8"/>
    <dbReference type="GeneID" id="5002448"/>
    <dbReference type="Gramene" id="ABO96606">
        <property type="protein sequence ID" value="ABO96606"/>
        <property type="gene ID" value="OSTLU_49818"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_49818"/>
    <dbReference type="eggNOG" id="KOG1191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019624_4_2_1"/>
    <dbReference type="OMA" id="EFHCHGG"/>
    <dbReference type="OrthoDB" id="188276at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14858">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.120:FF:000003">
        <property type="entry name" value="tRNA modification GTPase MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000494">
        <property type="entry name" value="tRNA modification GTPase MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="entry name" value="tRNA modification GTPase MnmE domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42714">
        <property type="entry name" value="TRNA MODIFICATION GTPASE GTPBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42714:SF2">
        <property type="entry name" value="TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116878">
        <property type="entry name" value="TrmE connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0630">Potassium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="13">
        <location>
            <begin position="279"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO96606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="525" mass="54962" checksum="DE39ACB9D61A3291" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZG8</accession>
    <name>A4RZG8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418569.1">
        <property type="nucleotide sequence ID" value="XM_001418532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZG8"/>
    <dbReference type="GeneID" id="5002605"/>
    <dbReference type="Gramene" id="ABO96862">
        <property type="protein sequence ID" value="ABO96862"/>
        <property type="gene ID" value="OSTLU_32381"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32381"/>
    <dbReference type="eggNOG" id="ENOG502SC9M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753136_0_0_1"/>
    <dbReference type="OMA" id="DVIPRMW"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043367">
        <property type="entry name" value="PLIP1/2/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46483">
        <property type="entry name" value="PHOSPHOLIPASE A1 PLIP2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46483:SF4">
        <property type="entry name" value="PHOSPHOLIPASE A1 PLIP2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="129"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="368" mass="40872" checksum="CE98BCF0DB02B82D" modified="2007-05-15" version="1">MKTKMKMKMKMKTASTRATSSSDASSSAAAAKDEEDDCVLATKCARMANFVYKGGGVESWMADDGLQTKARGVTGATGWCVCDDVERNARFIVVRGAAWSQPDTDRNKLSWQIAKIWPQALRKDRKTPVVCHQGVYEMVEEFWRDLVPWLSDETFDGTYYFTGHSLGGSMGLVVAARARELGLEEARVGGVYTFGAPPVLAYDRLAGNGPGSSIDDEPEVGMDEILRLVGFTRGASLVKQYVLAKDVIPRMWLSADPVFVAATKTDFIGGLLDWRRETFGEGMFTKNRFLYESIGDLYWLEYADGEQGKPTLSRYGGDDVLTKLRMNLDDITQSPLTAWQTIGDHNSQAYVDALQFLTIRRVINPSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZP2</accession>
    <name>A4RZP2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_16000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418607.1">
        <property type="nucleotide sequence ID" value="XM_001418570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZP2"/>
    <dbReference type="STRING" id="436017.A4RZP2"/>
    <dbReference type="GeneID" id="5002626"/>
    <dbReference type="Gramene" id="ABO96900">
        <property type="protein sequence ID" value="ABO96900"/>
        <property type="gene ID" value="OSTLU_16000"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16000"/>
    <dbReference type="HOGENOM" id="CLU_066329_0_0_1"/>
    <dbReference type="OMA" id="LMFCIDG"/>
    <dbReference type="OrthoDB" id="496389at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238">
        <property type="entry name" value="MEMBRANE BOUND PREDICTED REDOX MODULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF4">
        <property type="entry name" value="SLL1022 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="30294" checksum="3EE4F607E47BE0D4" modified="2007-05-15" version="1">MTVLWGTTSTQAEKKELMSAFIGSAAVETMLSLDNLVVFHQIFGTFKVPPSRRPGILVAGLPIMLVVRVTLFLSFHGVYTYVRVLFVLIGVFIIYQGVCVAYFSEDDDDNDDLSSNWIVKGVRGCFGNRMSTKYEGSAFYVRTPDGALQFTPLILVMVFIEASDLMFCIDGVSTIYVVGHTDLLAVVCGDCCAVLLVRALYPQLQGTVEIFPDLNYAVAATLVAVGVDMILTASKRELPVFVLVCFMVAVFIAGVVSSLVRGLISKTCADRKPATHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S049</accession>
    <name>A4S049_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_35755</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CKS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418912.1">
        <property type="nucleotide sequence ID" value="XM_001418875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S049"/>
    <dbReference type="STRING" id="436017.A4S049"/>
    <dbReference type="GeneID" id="5002756"/>
    <dbReference type="Gramene" id="ABO97205">
        <property type="protein sequence ID" value="ABO97205"/>
        <property type="gene ID" value="OSTLU_35755"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_35755"/>
    <dbReference type="eggNOG" id="KOG3484">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140546_2_0_1"/>
    <dbReference type="OMA" id="MHEPEPH"/>
    <dbReference type="OrthoDB" id="440676at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.170.10:FF:000003">
        <property type="entry name" value="Cyclin-dependent kinases regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00944">
        <property type="entry name" value="CKS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="75" mass="9079" checksum="19006ECA0A401B07" modified="2007-05-15" version="1">MPQIQYSEKYYDDVYEYRHVVLPPDIAKLLPKNRLLTETEWRGLGVQQSRGWVHYAIHRPEPHIMLYRRPKETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S087</accession>
    <name>A4S087_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418932.1">
        <property type="nucleotide sequence ID" value="XM_001418895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S087"/>
    <dbReference type="GeneID" id="5002686"/>
    <dbReference type="Gramene" id="ABO97225">
        <property type="protein sequence ID" value="ABO97225"/>
        <property type="gene ID" value="OSTLU_32653"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32653"/>
    <dbReference type="eggNOG" id="ENOG502SDR5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1646536_0_0_1"/>
    <dbReference type="OMA" id="CIKPITF"/>
    <dbReference type="OrthoDB" id="6239435at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="161" mass="17366" checksum="F8F40D23C73B2306" modified="2007-05-15" version="1">MGRAREYFVDKGLTPTDVVPAFVFHEVISVAFAASTWIAAYAIEPSRTVLKPLAKTKVAEKAAPLFRKTLAAAAKQTAKATTRVPALRAANAERLTLSLAESLFFRGCIKPITFGGKLWLSYQFIVWTKTVGRNAAKPLASASARMGAKRDRALGIALKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0E5</accession>
    <name>A4S0E5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_16194</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418731.1">
        <property type="nucleotide sequence ID" value="XM_001418694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0E5"/>
    <dbReference type="STRING" id="436017.A4S0E5"/>
    <dbReference type="GeneID" id="5002939"/>
    <dbReference type="Gramene" id="ABO97024">
        <property type="protein sequence ID" value="ABO97024"/>
        <property type="gene ID" value="OSTLU_16194"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16194"/>
    <dbReference type="eggNOG" id="KOG4182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006044_1_0_1"/>
    <dbReference type="OMA" id="LKYYHNC"/>
    <dbReference type="OrthoDB" id="245173at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="116"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO97024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="816" mass="88024" checksum="BF4B2D95C3826916" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0X6</accession>
    <name>A4S0X6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_32901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419264.1">
        <property type="nucleotide sequence ID" value="XM_001419227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0X6"/>
    <dbReference type="GeneID" id="5003235"/>
    <dbReference type="Gramene" id="ABO97557">
        <property type="protein sequence ID" value="ABO97557"/>
        <property type="gene ID" value="OSTLU_32901"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32901"/>
    <dbReference type="eggNOG" id="ENOG502RZ7W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1192562_0_0_1"/>
    <dbReference type="OrthoDB" id="2093442at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="65"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="249" mass="26782" checksum="C776FB49C4F82807" modified="2007-05-15" version="1">MVDGTDSATQQEVGMLTKIDFSSNLVRTENRATWDASQSSCAYSGSKESGVSKHFWTRISVSGRYVSVIGAHLKANPTQPSSCAQREAQVEVLRAIAQARYDAGDAVIVAGDLNDYSDRHVDAGNNSPTSKVLKRLRDFNDDGVDELEEVGGRIAQVSRYTWQSGSSKAKLDYILTSRADIEVVSAAIRHDLVTSSVSDHFPLVATLDIKPRNTSLLGTVGANSVTNATMATSVAVGIAVFAMTTIFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0Y6</accession>
    <name>A4S0Y6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_46324</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419057.1">
        <property type="nucleotide sequence ID" value="XM_001419020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0Y6"/>
    <dbReference type="STRING" id="436017.A4S0Y6"/>
    <dbReference type="GeneID" id="5003394"/>
    <dbReference type="Gramene" id="ABO97350">
        <property type="protein sequence ID" value="ABO97350"/>
        <property type="gene ID" value="OSTLU_46324"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_46324"/>
    <dbReference type="eggNOG" id="KOG2479">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024521_0_0_1"/>
    <dbReference type="OMA" id="CKHNGVI"/>
    <dbReference type="OrthoDB" id="16538at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007783">
        <property type="entry name" value="eIF3d"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05091">
        <property type="entry name" value="eIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="47208" checksum="B7938D70331EE341" modified="2007-05-15" version="1">MDEAARDLGVGAERERNRQARIQSRKAQQWNTWAYNRQQQQVHYSASVDIRPDWEVVEQIAFPEIIKQSLELAEAAPEDLATYGSVRWFDKSYDRVTPKSEVLLRRRTEEPPRNVTASEDPIIQKYAAEGTGNVFTTDGVLAAVMCAARSNYSWDIVIKKKDGKIFLDKRPDGNFDQLTVSETAQEPIPDDPEDINGVQQLSAEGTKANRAFVEQSLTVEKDAYKFGEPVPFFGEDDNDSIAYKYRKWNVDDTTKLVCRCELNAVSESKGMDKGKALTTLVKALNEFDSKVTGIDWRLKIETQRGAVVANELKNNANKLAKWTAMAVLAGAEQMKLGFVSRVHPRDPNAHAILNTQTYNTKDFAQQINIKEANMWGSLKLFLDTCRKFEDGSYICVKDPLKNILRFYKYEESASMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S119</accession>
    <name>A4S119_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Gamma tubulin complex component C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_93105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419076.1">
        <property type="nucleotide sequence ID" value="XM_001419039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S119"/>
    <dbReference type="STRING" id="436017.A4S119"/>
    <dbReference type="GeneID" id="5003339"/>
    <dbReference type="Gramene" id="ABO97369">
        <property type="protein sequence ID" value="ABO97369"/>
        <property type="gene ID" value="OSTLU_93105"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93105"/>
    <dbReference type="HOGENOM" id="CLU_291589_0_0_1"/>
    <dbReference type="OMA" id="LCFRARI"/>
    <dbReference type="OrthoDB" id="775571at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF70">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="8">
        <location>
            <begin position="885"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="626"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1206" mass="132976" checksum="753DEE9D422E141A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4S129</accession>
    <name>A4S129_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">L-aspartate oxidase</fullName>
            <ecNumber evidence="4 11">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_24902</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the oxidation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>L-aspartate + O2 = iminosuccinate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419291.1">
        <property type="nucleotide sequence ID" value="XM_001419254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S129"/>
    <dbReference type="STRING" id="436017.A4S129"/>
    <dbReference type="GeneID" id="5003363"/>
    <dbReference type="Gramene" id="ABO97584">
        <property type="protein sequence ID" value="ABO97584"/>
        <property type="gene ID" value="OSTLU_24902"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24902"/>
    <dbReference type="eggNOG" id="KOG2403">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_3_0_1"/>
    <dbReference type="OMA" id="HCVQWLI"/>
    <dbReference type="OrthoDB" id="71672at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000002">
        <property type="entry name" value="L-aspartate oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.100">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00551">
        <property type="entry name" value="nadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="L-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716:SF2">
        <property type="entry name" value="L-ASPARTATE OXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000171">
        <property type="entry name" value="SDHA_APRA_LASPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 11" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="13">
        <location>
            <begin position="28"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal" evidence="14">
        <location>
            <begin position="430"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000171-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="541" mass="58994" checksum="76EEFDDD72ED3BC0" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1G8</accession>
    <name>A4S1G8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_42531</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419363.1">
        <property type="nucleotide sequence ID" value="XM_001419326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1G8"/>
    <dbReference type="STRING" id="436017.A4S1G8"/>
    <dbReference type="GeneID" id="5003250"/>
    <dbReference type="Gramene" id="ABO97656">
        <property type="protein sequence ID" value="ABO97656"/>
        <property type="gene ID" value="OSTLU_42531"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_42531"/>
    <dbReference type="eggNOG" id="KOG0835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022000_4_1_1"/>
    <dbReference type="OMA" id="WEDVWSV"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20532">
        <property type="entry name" value="CYCLIN_CCNL_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21797">
        <property type="entry name" value="CycT2-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036580">
        <property type="entry name" value="Cyclin_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="40"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="5">
        <location>
            <begin position="154"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="156"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="34310" checksum="D13E80BD5BE232E9" modified="2007-05-15" version="1">MIHTSTAVDNFYVVDVKNTPSRSKDVDEETEFVQRIYGASLIRSACLLLRSPLSVVITAQTLLHRFYTKKSLTDYDVKLVATASIALACKLEEKDRKLRDVLNATRRAAQRHENKPRVVMAINTPEYEEYKSDAKNMEMVMLREFGFFAHVTPPHPFAYTLGTHLELDDDLVKRAWVLCNDSAMTALCVQYKPDVIACGCIYLAAKELGKALPSSPPWFCLVDGVTKENLEAIAETITAFHAVEKVDYKCLSGRGSERETKQRERSAHNSSSDRGRRRSRSRSPSERRVRRRDSRDYDRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1H0</accession>
    <name>A4S1H0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_16471</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419365.1">
        <property type="nucleotide sequence ID" value="XM_001419328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1H0"/>
    <dbReference type="GeneID" id="5003470"/>
    <dbReference type="Gramene" id="ABO97658">
        <property type="protein sequence ID" value="ABO97658"/>
        <property type="gene ID" value="OSTLU_16471"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16471"/>
    <dbReference type="HOGENOM" id="CLU_763654_0_0_1"/>
    <dbReference type="OMA" id="SHERWEP"/>
    <dbReference type="OrthoDB" id="195752at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051598">
        <property type="entry name" value="TSUP/Inactive_protease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN MJ0441-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701:SF2">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN YJNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="32693" checksum="39C27BFAD355E373" modified="2007-05-15" version="1">MNTVVRALTLGQVAVVVAACVAGALLVGAVGLGGVVILPALLLARACTPEVGIVSLFVAFTPTMALRVWMLRKIVPRDRFPTRLGGVAAAGGACGASVAGGALLDVVPREALTYVIGLVALVAGGKDVADSARRLRSRAARSRAGEGETVVTVEDGGDDGDDGDAALEMDGADAVDANESESKSDEYWLEPTTREMWLLFSIGVVVGMLSVLTGTGGPISFLPIVVLWKGKVNRKVMLSMSAIQSVFLGIAAIVSTTARGKKPDPGLVLLILPCGLVGVALGVRVLKYFSREWLTLFIGTILLAVGSFTVHQATEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1V6</accession>
    <name>A4S1V6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_3761</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419215.1">
        <property type="nucleotide sequence ID" value="XM_001419178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1V6"/>
    <dbReference type="STRING" id="436017.A4S1V6"/>
    <dbReference type="GeneID" id="5003211"/>
    <dbReference type="Gramene" id="ABO97508">
        <property type="protein sequence ID" value="ABO97508"/>
        <property type="gene ID" value="OSTLU_3761"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3761"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OMA" id="TFWNPDY"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="201"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO97508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="340" mass="37012" checksum="F992F0D0E438885A" modified="2007-05-15" version="1" fragment="single">KDVVAVAKTGSGKTLAFLLPMFHGMKRHGGVEGLVVAPTRELAIQIQAEAEKFGAAHGFQSVVVYGGASAYEQKNALRTKKPCLVIGTPGRLTDLMSQEGVLSLAELSVIVLDEADRMLDMGFEPQIKQIFGATPTKRQTLLFSATWPKSVRKLAAGYLNQDKSCVEEIFIGEGASDGELAANKAITQRFIEARDHEKDEHLYNLICEFPDESRVVVFANTKRRVENLAKTFAAEGFGTVSVHGDKSQADREASLRKFVENKAPLMMATDVAARGLDIKGVTHVINYDMARDVESYVHRIGRTGRAGELGAAVTFWNVDYDKPCTPALCKIARDAGQAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="113" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1Y2</accession>
    <name>A4S1Y2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Histone-lysine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SDG3504</name>
        <name evidence="14" type="ORF">OSTLU_16584</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419228.1">
        <property type="nucleotide sequence ID" value="XM_001419191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1Y2"/>
    <dbReference type="STRING" id="436017.A4S1Y2"/>
    <dbReference type="GeneID" id="5003491"/>
    <dbReference type="Gramene" id="ABO97521">
        <property type="protein sequence ID" value="ABO97521"/>
        <property type="gene ID" value="OSTLU_16584"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16584"/>
    <dbReference type="eggNOG" id="KOG1080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_536828_0_0_1"/>
    <dbReference type="OMA" id="PCGDKHA"/>
    <dbReference type="OrthoDB" id="496514at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10518">
        <property type="entry name" value="SET_SETD1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE ATX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHD"/>
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        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
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    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="49"/>
            <end position="100"/>
        </location>
    </feature>
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        <location>
            <begin position="104"/>
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        </location>
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            <begin position="346"/>
            <end position="467"/>
        </location>
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            <begin position="472"/>
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        </location>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
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            <dbReference type="EMBL" id="ABO97521.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="54768" checksum="3C7862377F87BDD4" modified="2007-05-15" version="1">MDKVVGYVRPTVRNRYRMSEAEVVERRRREAIENAGADETPSIFRTPSVEKCDVCDSVREFDQDVLVQCDECMILVHMGCYGVTTAPTGGRWLCRACELGLRTPPRCALCPNVGGAMKPTLCGRWCHVVCALWAECTFAHPDGVAEPIEGVNMVPAESLKATCAVCEQSYGACAQCMGTKKCQKAFHVYCARDAECGYIAHSRTVAQLKQAGIRKFIVGYEQPLRNTDTLLFPSCPACANWRGRKRKRRASTPKKRTQTPKTRPTVDSREVEDKDEDAKPLQCAKFDPLGAYARALTVSPKDSIPYLVTGARTSRLESFSLRAVALADPPRNLNERFERMKATISDRLTLGKSYIHGYGLFAKRAHARGEMIIDYVGEIVRPVVADIRERDVYDTCFGNGTYIFALGGDDQPVRLDATCAGNLANLANHSCAPNAHSRQVYAANDNHICLFASRNIQPGEEILYEYRLGADQTLRCNCGAANCRGVVNFTAEHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4S207</accession>
    <name>A4S207_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_001419419.1"/>
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        <property type="gene ID" value="OSTLU_16605"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_1527234_0_0_1"/>
    <dbReference type="OMA" id="PKDTMPF"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
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        </location>
    </feature>
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        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="18965" checksum="A4D4FA1FC6DF7470" modified="2007-05-15" version="1">MIARVSTTSTVTARASARQNKTERRDAAVVRANAKEQACAAVLAMTVMASPLANAAVEVAQVAKGDTKSLASDLFAEQQTKSTPAAPKKTKQLASPSMPKAPSFSAPSLPSFSAPSISLPSFSTAKKTDAKAPAAKEAPAPKAKKESGAGPNLALTLLVLFSPLLAVQAVSFQTFARIAKQSAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S326</accession>
    <name>A4S326_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_25083</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419639.1">
        <property type="nucleotide sequence ID" value="XM_001419602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S326"/>
    <dbReference type="STRING" id="436017.A4S326"/>
    <dbReference type="GeneID" id="5003848"/>
    <dbReference type="Gramene" id="ABO97932">
        <property type="protein sequence ID" value="ABO97932"/>
        <property type="gene ID" value="OSTLU_25083"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25083"/>
    <dbReference type="eggNOG" id="KOG1525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_375269_0_0_1"/>
    <dbReference type="OrthoDB" id="515344at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05162">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047365">
        <property type="entry name" value="Tudor_AtPTM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21743">
        <property type="entry name" value="PTM_DIR17_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="4">
        <location>
            <begin position="387"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="245"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="457"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="689"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO97932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="740" mass="80921" checksum="624E7A886A2A9C45" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S330</accession>
    <name>A4S330_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_88308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419641.1">
        <property type="nucleotide sequence ID" value="XM_001419604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S330"/>
    <dbReference type="STRING" id="436017.A4S330"/>
    <dbReference type="GeneID" id="5003853"/>
    <dbReference type="Gramene" id="ABO97934">
        <property type="protein sequence ID" value="ABO97934"/>
        <property type="gene ID" value="OSTLU_88308"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88308"/>
    <dbReference type="eggNOG" id="KOG0092">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_10_2_1"/>
    <dbReference type="OMA" id="RYWANEL"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000808">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="183" mass="19858" checksum="285F494626572967" modified="2007-05-15" version="1" fragment="single">VKLVLLGASGAGKTALSTRFVRGTFDGENASATVGAAFASTTRALDDARARIKFEIWDTAGQERYASLAPLYYRGATAAMIAFDARDGASFERARYWAEELRKHGDARCRVLLVGNKIDAVRDDERATAREACEALAREYGMAAYRETSAKTGEGVQEAFEDVARAVMTREMSAREDATVVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A4S351</accession>
    <name>A4S351_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_25087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419652.1">
        <property type="nucleotide sequence ID" value="XM_001419615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S351"/>
    <dbReference type="GeneID" id="5003863"/>
    <dbReference type="Gramene" id="ABO97945">
        <property type="protein sequence ID" value="ABO97945"/>
        <property type="gene ID" value="OSTLU_25087"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_25087"/>
    <dbReference type="HOGENOM" id="CLU_485210_0_0_1"/>
    <dbReference type="OMA" id="CTIADPF"/>
    <dbReference type="OrthoDB" id="10501855at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="562" mass="62024" checksum="F8942B47882CA8F2" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S387</accession>
    <name>A4S387_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">15-cis-phytoene synthase</fullName>
            <ecNumber evidence="3">2.5.1.32</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_5449</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34475"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.32"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="3"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419874.1">
        <property type="nucleotide sequence ID" value="XM_001419837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S387"/>
    <dbReference type="STRING" id="436017.A4S387"/>
    <dbReference type="GeneID" id="5004202"/>
    <dbReference type="Gramene" id="ABO98167">
        <property type="protein sequence ID" value="ABO98167"/>
        <property type="gene ID" value="OSTLU_5449"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5449"/>
    <dbReference type="eggNOG" id="KOG1459">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037269_1_3_1"/>
    <dbReference type="OMA" id="HIVAFFD"/>
    <dbReference type="OrthoDB" id="6600518at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046905">
        <property type="term" value="F:15-cis-phytoene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480">
        <property type="entry name" value="BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="302" mass="34103" checksum="C71F34E5061B396D" modified="2007-05-15" version="1" fragment="single">AQRATSTSAATVEQARAQAKETTRTYARSFYWASQFMTKGREDAYALYCWCRELDEIVDGADGADEERRAKLNRSEANLEAMFRKGTLTEPSYADVALSDTLARVEGLRIGPFKDMISGMRRDIDDARFERVEDVLNYAYQVAGTVALMILPILTLGSVDDEQKAAKREERGVALGIALQLTNIVRDVGEDARQRGRVYIADEDLKLFELTRDDVLSMKTPTTNYMALIEYQIQRALFYYSKALEGIDLLPPLARPPTKLIAGLYQRIAFAVRENDYDNLSKRAFSSTYEKLTLTPKLLLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3B0</accession>
    <name>A4S3B0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_94785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420063.1">
        <property type="nucleotide sequence ID" value="XM_001420026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3B0"/>
    <dbReference type="STRING" id="436017.A4S3B0"/>
    <dbReference type="GeneID" id="5004123"/>
    <dbReference type="Gramene" id="ABO98356">
        <property type="protein sequence ID" value="ABO98356"/>
        <property type="gene ID" value="OSTLU_94785"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94785"/>
    <dbReference type="HOGENOM" id="CLU_1269773_0_0_1"/>
    <dbReference type="OrthoDB" id="515250at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="3">
        <location>
            <begin position="48"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="218" mass="23875" checksum="F0D4421009EA1193" modified="2007-05-15" version="1" fragment="single">MPKSASVLSLDSTAATSAGSDGANTTQVGLGREDKDLFPRSDVALANERVQNQLELEKCKHLLENFINQPEALNFRDPIDPQTVERANYGSVVEEPMGLTIVLNKLRMNAFASSREVWKACNSIWSNCRSCYPSSSRMRKLCDLAELMFTTTWRAQGLNKFSDASDDDSCDAPPGMKSLNDFKNAGPKTATRPPSGAVTSARVGRSRVASFKCDVCKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3J8</accession>
    <name>A4S3J8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_38040</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420108.1">
        <property type="nucleotide sequence ID" value="XM_001420071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3J8"/>
    <dbReference type="STRING" id="436017.A4S3J8"/>
    <dbReference type="GeneID" id="5004062"/>
    <dbReference type="Gramene" id="ABO98401">
        <property type="protein sequence ID" value="ABO98401"/>
        <property type="gene ID" value="OSTLU_38040"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38040"/>
    <dbReference type="eggNOG" id="KOG0731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_16_2_1"/>
    <dbReference type="OMA" id="NLACEMV"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF58">
        <property type="entry name" value="INACTIVE ATP-DEPENDENT ZINC METALLOPROTEASE FTSHI 5, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="94"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO98401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="437" mass="48266" checksum="D4DA6249A5717DA6" modified="2007-05-15" version="1" fragment="single">MEKYPRWLEITAFLFNALTPMVMVFYAWLIYEGTYKDSSEDMFGNMTTRNYDSNVRQGMTLKDITGIDNVKAEMFELISYLKDFEKYNSMGARIPAGVLLCGPPGTGKTLLARCVAGEANVPFFSCAGTEFMEMFVGVGAARIRNLFDQAKKVAPCIIFIDEFDAVGTKRTETQSGQVYGNDEATATINQMLTEMDGFSTATGIMVLAATNRPQVLDPALIRAGRFDRIIEMGLPNKKSRQEILFLHCNKPSFASSVDPNLDYEYLARQTAGFSGADIENLTKSAVMRCAQGEKALASTGDFFLARDRMLEDTLIAQLDAYERDSVVNYYAAQAVVAMHMPSYDEISKVTVFNGGVATGQIVYVPDEVDSPAARTVRSMEYYEAKLCVLLAGQMAERYLYGPENVTTRGMHDVAAATNLACEMVMQNGWSDLGPIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S426</accession>
    <name>A4S426_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="8">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_26259</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
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                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
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                <person name="Pazour G.J."/>
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                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
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        <reaction evidence="8">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
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        </location>
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        </source>
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</entry>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
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                <person name="Jabbari K."/>
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                <person name="Robbens S."/>
                <person name="Werner G."/>
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                <person name="Paulsen I."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
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                <person name="Rouze P."/>
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                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
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                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
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                <person name="Werner G."/>
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                <person name="Pazour G.J."/>
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                <person name="Paulsen I."/>
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                <person name="Schmutz J."/>
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            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4H7"/>
    <dbReference type="STRING" id="436017.A4S4H7"/>
    <dbReference type="GeneID" id="5004471"/>
    <dbReference type="Gramene" id="ABO98559">
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        <property type="gene ID" value="OSTLU_26414"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26414"/>
    <dbReference type="eggNOG" id="KOG3710">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1063156_0_0_1"/>
    <dbReference type="OrthoDB" id="441695at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="140"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="262" mass="28380" checksum="6183B6980839A5F8" modified="2007-05-15" version="1">MKAMLEGLEYAPEDNAAATTAATAETVGYAFSSDHLRALERDGYVVVDDLISQDVARAAAASARAMYDRGVMQNLRQEGRDDDVAVLATSSLPAGDEFAGLRPCVEALLRVPDDLRRVVARVDDDALGADVVSKVRACRAPDRLMLARYGSESCRYVPHLDNDPSDDANDAGSPGLRPSDRVFTLIAYLNPDWDATRGGRFRAYRPGVAADAASPSDFVDIDPILGRVVVFDAAKLLHEVRPSFHDRYAVTVWTRGAELLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4P9</accession>
    <name>A4S4P9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_44270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420474.1">
        <property type="nucleotide sequence ID" value="XM_001420437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4P9"/>
    <dbReference type="STRING" id="436017.A4S4P9"/>
    <dbReference type="GeneID" id="5004549"/>
    <dbReference type="Gramene" id="ABO98767">
        <property type="protein sequence ID" value="ABO98767"/>
        <property type="gene ID" value="OSTLU_44270"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44270"/>
    <dbReference type="eggNOG" id="KOG2764">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_2_1"/>
    <dbReference type="OMA" id="KATCYPG"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903189">
        <property type="term" value="P:glyoxal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03135">
        <property type="entry name" value="GATase1_DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000015">
        <property type="entry name" value="Protein DJ-1 homolog C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006287">
        <property type="entry name" value="DJ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01383">
        <property type="entry name" value="not_thiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF12">
        <property type="entry name" value="PARKINSON DISEASE PROTEIN 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="4">
        <location>
            <begin position="31"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="253" mass="27036" checksum="DB17E631D97041B7" modified="2007-05-15" version="1">MRARTRTRTQSRTQSRTQSQSNARQRATAPTVLVPIARGSEEMETVIIVDVLRRAGADVTVASIEPGDDDETRRDDDDDAARRDDAVECSRGVRIVPDARLRDLARVETRAWDLIALPGGMPGAANLAKSERLTRALTRQMETPGALVAAMCASPGVVLAPRGMLDGLACTAHPAFVKDLPSDASANGRVVVDGDVVTSRGPGTALEFALALAEKLFGADKAREVAAPMVLPPIDHSSPRVANEWRLLDAEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Q8</accession>
    <name>A4S4Q8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
            <ecNumber evidence="2">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_88612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyltransferase 77 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420477.1">
        <property type="nucleotide sequence ID" value="XM_001420440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Q8"/>
    <dbReference type="STRING" id="436017.A4S4Q8"/>
    <dbReference type="CAZy" id="GT77">
        <property type="family name" value="Glycosyltransferase Family 77"/>
    </dbReference>
    <dbReference type="GeneID" id="5004555"/>
    <dbReference type="Gramene" id="ABO98770">
        <property type="protein sequence ID" value="ABO98770"/>
        <property type="gene ID" value="OSTLU_88612"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88612"/>
    <dbReference type="eggNOG" id="ENOG502QSJ9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_471436_0_0_1"/>
    <dbReference type="OMA" id="ARCYCDK"/>
    <dbReference type="OrthoDB" id="540503at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052636">
        <property type="term" value="F:arabinosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052325">
        <property type="term" value="P:cell wall pectin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053250">
        <property type="entry name" value="Glycosyltransferase_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46936">
        <property type="entry name" value="ARABINOSYLTRANSFERASE XEG113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46936:SF1">
        <property type="entry name" value="ARABINOSYLTRANSFERASE XEG113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="4">
        <location>
            <begin position="68"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="613"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="634" mass="71032" checksum="DDD7B384422FCA14" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Z0</accession>
    <name>A4S4Z0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="19">CaCA family transporter: sodium ion/potassium ion/calcium ion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_2890</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420352.1">
        <property type="nucleotide sequence ID" value="XM_001420315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Z0"/>
    <dbReference type="STRING" id="436017.A4S4Z0"/>
    <dbReference type="GeneID" id="5004405"/>
    <dbReference type="Gramene" id="ABO98645">
        <property type="protein sequence ID" value="ABO98645"/>
        <property type="gene ID" value="OSTLU_2890"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_2890"/>
    <dbReference type="eggNOG" id="KOG1307">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007948_5_0_1"/>
    <dbReference type="OMA" id="RLWAWIT"/>
    <dbReference type="OrthoDB" id="2127281at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008273">
        <property type="term" value="F:calcium, potassium:sodium antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="sodium/potassium/calcium exchanger 5 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00367">
        <property type="entry name" value="calcium/sodium antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846:SF8">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YRBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="SODIUM/POTASSIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="16" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="10" id="KW-0769">Symport</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="284"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="18">
        <location>
            <begin position="7"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="18">
        <location>
            <begin position="312"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABO98645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="431" mass="46496" checksum="8ACCDC6B1BA691E1" modified="2007-05-15" version="1" fragment="single">GGIFAYLVGVIYLFIGIAIVCDDFFVASLEKICEALGLSDDVAGATFMAAGSSAPELASSAMSLINSGTDNALGVGTIVGSAVFNILVIIGTTVIFAGQTLKLDWKPLARDCSFYFAAIVGIVATFNGGRVNWWEGLIYVFLYCLYIAFMWKNVYFMKLLDDKFGDYLGRPDAAVEMEEAAGGGLGAQSASKATTSAMSKELSFTGSIYVGFAAQRFKAGLGNKQHRAKALSPGQLRAIRNATEKVTWSHHHVKHAPTEDGVASEDGDDETNPFVMPAEWKDRPIWALSLPWYALFTISIPPCHNPKWEKWYFGSFLASIGWIGIISHFMVEWCARIGCLLKIPAIVMGTTVLAAGTSIPDALSSISVAKDGFADMAVANAVGSNVFDIWLGLGLPWLLYLSWQKPSYITVSTTELLPSSLILLGVLILYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S552</accession>
    <name>A4S552_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="gene ID" value="OSTLU_26639"/>
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        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="104" mass="11595" checksum="A8768542F1773FD7" modified="2007-05-15" version="1">MSEFAPPSYTGDPNLARCSEEYFKLGFWGLQFGLAFCALGGARFSRIAPGLSGDTALALSEEAANRRREKAGKRRRSHLQKGFGDKTGNAYQLRALDFRRQNMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S567</accession>
    <name>A4S567_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_17468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001420352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S567"/>
    <dbReference type="GeneID" id="5004505"/>
    <dbReference type="Gramene" id="ABO98682">
        <property type="protein sequence ID" value="ABO98682"/>
        <property type="gene ID" value="OSTLU_17468"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17468"/>
    <dbReference type="eggNOG" id="ENOG502QU4P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_297782_0_0_1"/>
    <dbReference type="OMA" id="PPWIRQR"/>
    <dbReference type="OrthoDB" id="511341at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043367">
        <property type="entry name" value="PLIP1/2/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46483">
        <property type="entry name" value="PHOSPHOLIPASE A1 PLIP2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46483:SF4">
        <property type="entry name" value="PHOSPHOLIPASE A1 PLIP2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="784"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="815"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="4">
        <location>
            <begin position="719"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1078"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="320"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1097" mass="118568" checksum="AB6B06D9B7932E4C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5R2</accession>
    <name>A4S5R2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_39103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420653.1">
        <property type="nucleotide sequence ID" value="XM_001420616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5R2"/>
    <dbReference type="STRING" id="436017.A4S5R2"/>
    <dbReference type="GeneID" id="5004916"/>
    <dbReference type="Gramene" id="ABO98946">
        <property type="protein sequence ID" value="ABO98946"/>
        <property type="gene ID" value="OSTLU_39103"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39103"/>
    <dbReference type="eggNOG" id="KOG0891">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000178_9_2_1"/>
    <dbReference type="OMA" id="IEWMNDT"/>
    <dbReference type="OrthoDB" id="498235at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004677">
        <property type="term" value="F:DNA-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05172">
        <property type="entry name" value="PIKKc_DNA-PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037706">
        <property type="entry name" value="DNA-PK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF68">
        <property type="entry name" value="DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="1">
        <location>
            <begin position="90"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="2">
        <location>
            <begin position="451"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="483" mass="53502" checksum="2B10657235C40DE6" modified="2007-05-15" version="1">MLTSAIATARREKTSVNAALKHAEAQIVAVWVKEFPGLNNASRIRLSDFSSWFASYASFAGVSTALEIPGQYDNINAPPDMERHVTIMGFAPEVQVFESKQRPKKITMRGSDGRDYQFIVKGGEDLRQDERIQRLFRAMNGLLASNTESRGRGLEVRTFHVSPLSNRTGLIEFLRKTSPLLRLLNKPVEEANVTAFVEHQRWIKERATGLGKRKRESAHVDATTHSDYLSAIGKASKDDSVAILTRLKSATTSPDALRKILFTAAGSAEAFVMMRQSFATSLASSSICGYVAGVGDRHLDNILLDISTGELVHIDFGYAFGTATHALPIPELVPFRATPALLDVFSPLNARTWLETDMCRTMKALQDGSTLLKGVMDIFLRDPLIDWERESVSAGTQSHIQNRITRAWGKLELDNPAVVVVDECESKHKNSAHWTDLRKTLVGANAPPAKKCTDVEHQIRALLDLATNPELLAVAWSGWRPWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5U6</accession>
    <name>A4S5U6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_26886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420672.1">
        <property type="nucleotide sequence ID" value="XM_001420635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5U6"/>
    <dbReference type="STRING" id="436017.A4S5U6"/>
    <dbReference type="GeneID" id="5004871"/>
    <dbReference type="Gramene" id="ABO98965">
        <property type="protein sequence ID" value="ABO98965"/>
        <property type="gene ID" value="OSTLU_26886"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26886"/>
    <dbReference type="eggNOG" id="KOG0135">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_558291_0_0_1"/>
    <dbReference type="OMA" id="WIRFTVQ"/>
    <dbReference type="OrthoDB" id="538336at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="492" mass="54075" checksum="6FE2366A91C6BB32" modified="2007-05-15" version="1">MTRDDHADVHAVARALARAPKRATRRTAKALRALVSRRGALTFTDVEDDPARFFAAHRALATHATTLGPGFWIRFTVQYNLFAGTCAALGTEAQRARLETLRRRGTLGCFCLTERLAGVNSGLVVHTRADWDGKTGGYVINSGEGDGGTKNWISQGLTADAAVVVANLFVKGRSFGPHGFLVTMREGAFGRLARGITVGDMGLKTTGNDLDNAWVRFDDFRAPAESLLAKYGDVDASTGEYVAKKEGIRTMDMIGQRLFTGRVAVAQAALTFVRRLFDDTKRYSDQKPCTMRGDSPALTDVPQLRALYDEGYATIDRLDAYVKQCENELCQCLRRREIPDAVLVQAIAVAKIKAVEGAIDLAFRLKQEVGSYALMSGTGFDNTDFLQCCKFAEGDSRILSQKLARDCFGAFQRNDQRSAVGVKSEIELDLCQRIDEHMRDAREANANVSKIEAWDSAWREVYRLAEVICERVMHEKSFAAAAAAGSVTRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5X9</accession>
    <name>A4S5X9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_39280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420688.1">
        <property type="nucleotide sequence ID" value="XM_001420651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5X9"/>
    <dbReference type="STRING" id="436017.A4S5X9"/>
    <dbReference type="GeneID" id="5004707"/>
    <dbReference type="Gramene" id="ABO98981">
        <property type="protein sequence ID" value="ABO98981"/>
        <property type="gene ID" value="OSTLU_39280"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39280"/>
    <dbReference type="HOGENOM" id="CLU_1840313_0_0_1"/>
    <dbReference type="OrthoDB" id="1476984at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254:SF4">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605493-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="140" mass="15105" checksum="A6F758DFF0B9E76C" modified="2007-05-15" version="1" fragment="single">MESPEYEAFEQTGPNECVVMESVGPWESVGGDIKFLRLAQLKCAGLVTDGSVRDTAVLREYGFPVFSISTTPRQGPHVHQPWEANGVITCGGIVVRPGDAIIGDQDGVVVIPASHAQEVYDIAHSREIVEDIVKTELATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>A4S631</accession>
    <name>A4S631_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic</fullName>
            <shortName evidence="6">RA</shortName>
            <shortName evidence="6">RuBisCO activase</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_3956</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Plastid</location>
            <location evidence="1 6">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RuBisCO activase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420873.1">
        <property type="nucleotide sequence ID" value="XM_001420836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S631"/>
    <dbReference type="STRING" id="436017.A4S631"/>
    <dbReference type="GeneID" id="5004862"/>
    <dbReference type="Gramene" id="ABO99166">
        <property type="protein sequence ID" value="ABO99166"/>
        <property type="gene ID" value="OSTLU_3956"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_3956"/>
    <dbReference type="eggNOG" id="KOG0651">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038420_1_0_1"/>
    <dbReference type="OMA" id="QQSSWEA"/>
    <dbReference type="OrthoDB" id="2014558at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046863">
        <property type="term" value="F:ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044960">
        <property type="entry name" value="RCA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048571">
        <property type="entry name" value="RuBisCO_activase_AAA_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32429">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32429:SF11">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE_OXYGENASE ACTIVASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21228">
        <property type="entry name" value="RuBisCO_activase_AAA_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="7">
        <location>
            <begin position="136"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Ribulose bisphosphate carboxylase/oxygenase activase AAA helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="342" mass="37849" checksum="83704DA4E1BD8893" modified="2007-05-15" version="1" fragment="single">RPRRPSSWTAREKTQKNIGRDYLVELGKNDTGNTNTNVGARQGVVDDVFTRNATGEFQLGADSDIASGELRYRYQEARKFKNLVGDYHCPPAFMEKVSGHLVKNFLFGGGLRHVREMTNEAGVVVQPPNTPLILGVWGGKGCGKSFNLELACKAMGVTPIITSAGELEDENAGAPGRLIRERYKRAGEILRRTGVMSCLIINDVDAGIGWFKDTQHTVNNQTVCGTLMNLCDHPELVSLGEDRGEDGKNLQTARVPIIVTGNDLSTVYAPLLRDGRMDKWYWNPSRDDICDIVHALFKDEVDWSPDATARLVNAFPGQPLDFFGAARAKVYDDAVSRWMCEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S647</accession>
    <name>A4S647_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421028.1">
        <property type="nucleotide sequence ID" value="XM_001420991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S647"/>
    <dbReference type="STRING" id="436017.A4S647"/>
    <dbReference type="GeneID" id="5005058"/>
    <dbReference type="Gramene" id="ABO99321">
        <property type="protein sequence ID" value="ABO99321"/>
        <property type="gene ID" value="OSTLU_93571"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93571"/>
    <dbReference type="HOGENOM" id="CLU_440339_0_0_1"/>
    <dbReference type="OMA" id="WQRVEWI"/>
    <dbReference type="OrthoDB" id="498655at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="621" mass="66292" checksum="165BE61209D6D9CC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S669</accession>
    <name>A4S669_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_41640</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420893.1">
        <property type="nucleotide sequence ID" value="XM_001420856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S669"/>
    <dbReference type="STRING" id="436017.A4S669"/>
    <dbReference type="GeneID" id="5005070"/>
    <dbReference type="Gramene" id="ABO99186">
        <property type="protein sequence ID" value="ABO99186"/>
        <property type="gene ID" value="OSTLU_41640"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_41640"/>
    <dbReference type="eggNOG" id="KOG2103">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005034_3_0_1"/>
    <dbReference type="OMA" id="IWPESAR"/>
    <dbReference type="OrthoDB" id="498028at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="11">
        <location>
            <begin position="192"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO99186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="398" mass="43755" checksum="163870A65C95FF43" modified="2007-05-15" version="1">MAKSSTTTTFFVVNQFTGELFGKPTIVDVAAAHVLPFTLPTGEDALIVVDAEGRAATYPKRAEPSALDALNSLSYYKVDQTTNEVRGYKLRKASDGMTTMDSLHTWTVSFPPAAGSIVGFANKPTSEERVNSWTRVPGDRSTLFKYLNPNTIFVATSDGTAVHVSLIDGVTGRILYRVRHGDARGPVKAVVCENWVAYHYFNTRAKRYAMSVLEMFDDGEERRNLATSSSLNPPPLRIIGQSYYVRPEAKMISVTRSKRGVTEPAVLLATANDQVAAIDKRFLDPRRPNKPSAADREEGLIPYTEVIPIFPGSWVTHKRVVHGLRGLVTAPAELESSIHFVAHGLDLFYARITPSQSFDALDDDFNYVLLVFTLVALAVGAFVTKRAADAADANHAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S697</accession>
    <name>A4S697_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">triose-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_7124</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421055.1">
        <property type="nucleotide sequence ID" value="XM_001421018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S697"/>
    <dbReference type="STRING" id="436017.A4S697"/>
    <dbReference type="GeneID" id="5005013"/>
    <dbReference type="Gramene" id="ABO99348">
        <property type="protein sequence ID" value="ABO99348"/>
        <property type="gene ID" value="OSTLU_7124"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7124"/>
    <dbReference type="eggNOG" id="KOG1643">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024251_2_3_1"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000016">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF42">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO99348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="245" mass="25966" checksum="B094C3588BFEAB1C" modified="2007-05-15" version="1" fragment="single">MAGNWKLNPKTLDEARTLAALVGAAARDGGIGTNKSKTEVFVCPPAPFAAEVARTLEGSGVAVGAQNIYFEASGAFTGEMSAEMAKSVGCTHVLIGHSERRELFGETDEMTRLKTRKTLDCGMTAVLCIGETKEEYERGEAKKVCNRQLSAALSGVEADEMSKVIIAYEPVWAIGTGLTATPAIAQSVHAGIRQWFRTNYGESVAAKIQIQYGGSVKPETVDELMQAPDVDGCLVGGASLNAEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6C7</accession>
    <name>A4S6C7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_5458</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421070.1">
        <property type="nucleotide sequence ID" value="XM_001421033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6C7"/>
    <dbReference type="STRING" id="436017.A4S6C7"/>
    <dbReference type="GeneID" id="5005127"/>
    <dbReference type="Gramene" id="ABO99363">
        <property type="protein sequence ID" value="ABO99363"/>
        <property type="gene ID" value="OSTLU_5458"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5458"/>
    <dbReference type="eggNOG" id="KOG1465">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_4_3_1"/>
    <dbReference type="OMA" id="ASDHICT"/>
    <dbReference type="OrthoDB" id="269919at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051855">
        <property type="entry name" value="eIF2B_beta_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="301" mass="30825" checksum="3A8BA320843D3EE6" modified="2007-05-15" version="1" fragment="single">EIIASVRAIGGSLAVLKREHLLVGNVARRVLRVIRDEGATSERGDGGGGGESGGGGGGAATKKLKKDVIDTAHEVIEEMETVSTNIASQSSDFVTNGCVVMTMGSNASAGTGLAEAFLRDANKKRSASEGGGGFSVVVAESAPRYDGHAMAKSLAERGVRDVSLICDSAVYATMPSVKLCVLSARGVLADGSALVDSGAYNIALAAKAHSVPVLMLAGSYAISPKTQKEAGFDRVYGFGSPSTALGYGERGADPDAVVINPSFEFVPAELISVFVTDHGAHCPGFINVLLSEMYSPLDSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6F7</accession>
    <name>A4S6F7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_88941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421085.1">
        <property type="nucleotide sequence ID" value="XM_001421048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6F7"/>
    <dbReference type="STRING" id="436017.A4S6F7"/>
    <dbReference type="GeneID" id="5005142"/>
    <dbReference type="Gramene" id="ABO99378">
        <property type="protein sequence ID" value="ABO99378"/>
        <property type="gene ID" value="OSTLU_88941"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88941"/>
    <dbReference type="eggNOG" id="ENOG502QUFP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035287_2_0_1"/>
    <dbReference type="OMA" id="TARSHEW"/>
    <dbReference type="OrthoDB" id="1716402at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008507">
        <property type="entry name" value="DUF789"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31343">
        <property type="entry name" value="T15D22.8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31343:SF42">
        <property type="entry name" value="T15D22.8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05623">
        <property type="entry name" value="DUF789"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="279" mass="31015" checksum="00702AB1F247390C" modified="2007-05-15" version="1">MANIEAFVASSAPVFSSRAESSRDFALSELWDAFTEPSAFGAEVPLRLQDGQPCVSQYYVPFLSGMQLFVRGDGEDGEDGEDGARRRRVGTGTRLIYEFFEKASPYSRAPFREIIDLILDERAELRTMTSADLAPSSWMSVAWYPIYRIPQGTMLHDVQGCFLTYHALYAGELCDGDIACPLPPEMTMLSEDLLALRAARAKERASASDDAGAGGGSTAAPHAHILRPFGLSMYKMQGDVWAANDDVTDWMNKLMDGAYTWLRMRKTVHPDYEFFSHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Q8</accession>
    <name>A4S6Q8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Signal peptidase complex subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Microsomal signal peptidase 22 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_36742</name>
        <name evidence="11" type="ORF">OSTLU_93629</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SPCS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421133.1">
        <property type="nucleotide sequence ID" value="XM_001421096.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422822.1">
        <property type="nucleotide sequence ID" value="XM_001422785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6Q8"/>
    <dbReference type="STRING" id="436017.A4S6Q8"/>
    <dbReference type="GeneID" id="5005196"/>
    <dbReference type="GeneID" id="5006880"/>
    <dbReference type="Gramene" id="ABO99426">
        <property type="protein sequence ID" value="ABO99426"/>
        <property type="gene ID" value="OSTLU_93629"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01181">
        <property type="protein sequence ID" value="ABP01181"/>
        <property type="gene ID" value="OSTLU_36742"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_36742"/>
    <dbReference type="KEGG" id="olu:OSTLU_93629"/>
    <dbReference type="eggNOG" id="KOG3372">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068714_1_0_1"/>
    <dbReference type="OMA" id="LAIMCIM"/>
    <dbReference type="OrthoDB" id="498559at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007653">
        <property type="entry name" value="SPC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04573">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016089">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007635052" description="Signal peptidase complex subunit 3" evidence="10">
        <location>
            <begin position="28"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO99426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <name evidence="2" type="ORF">OSTLU_27288</name>
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        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
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    </organism>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="OMA" id="DAWFNIT"/>
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="655"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="687"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="946" mass="106045" checksum="D870FCECA725AF43" modified="2007-05-15" version="1"> </sequence>
</entry>
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        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_27303"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502QQSA">
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    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058032">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CDP1-like_IMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044685">
        <property type="entry name" value="CPD1-like"/>
    </dbReference>
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        <property type="entry name" value="PLASTID DIVISION PROTEIN CDP1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33925:SF1">
        <property type="entry name" value="PROTEIN ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARC6"/>
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    </dbReference>
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    </dbReference>
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        </location>
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            <end position="499"/>
        </location>
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        <location>
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            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25515"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="762" mass="82466" checksum="5124B6ABA76AC44E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7P3</accession>
    <name>A4S7P3_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <lineage>
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        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
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        <property type="gene ID" value="OSTLU_27569"/>
    </dbReference>
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    <dbReference type="OMA" id="ERGGCAN"/>
    <dbReference type="OrthoDB" id="534245at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
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    </dbReference>
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        <property type="entry name" value="OS01G0867200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="105"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABO99783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="385" mass="41357" checksum="FE329D9724AF389F" modified="2007-05-15" version="1">MAPANLPKSIAHGPSALEVRAFAHARVVFPSPSHPSPGEHHASRACVYNARASDEETYDVIIASGCDVLACEINLSDSNVDRGKENALRPTAVSETAARRRRLESSSTKREIQSISLSEDARKLLMVDNYGVVDVMTRDVGGGGKFGDGSRLAAVGANDVEGVGGWCGAVTGGGEDGKIYVAKSSQRVVDLYDGDRRVRRIRTLLAPYDIELTAVGNGGNVFVVAEGHQLAVYDDRIAERGGCANRISLGYNKPLYAVSTSRTPGLESVIACGGAERVVHVLDIRKWGAMERWRNAAKFDITQLELSTSSPGFAYVAGLDYECMCGSWRTQKSDGGFSFRADTRWMGLHSCKTACGRGDVLAGWAESGHVYALRTQPAIDSFRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7Y5</accession>
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    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="5 6">
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        <lineage>
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            <taxon>Mamiellophyceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421530.1">
        <property type="nucleotide sequence ID" value="XM_001421493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7Y5"/>
    <dbReference type="STRING" id="436017.A4S7Y5"/>
    <dbReference type="GeneID" id="5005443"/>
    <dbReference type="Gramene" id="ABO99823">
        <property type="protein sequence ID" value="ABO99823"/>
        <property type="gene ID" value="OSTLU_89214"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89214"/>
    <dbReference type="eggNOG" id="KOG0531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_615934_0_0_1"/>
    <dbReference type="OMA" id="RWSEVKV"/>
    <dbReference type="OrthoDB" id="542800at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF7">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="257"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="384"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="445" mass="48711" checksum="47FEBC29A358575C" modified="2007-05-15" version="1">MKTLTPELASARTIGDACALKACSLNAVEDDVLARAETTSGAIKKLDVSENALSDLSGVRSTSLTWFSCANNVLKSDALAALGQNCPRIRTLNVSGNDGLRTLRGVENMHALAALIAKECGLRDIDHVRGLKELNTLACAECELRDVGDALSESPALRKVNLSKNALSKLGIDALQSSRGLRELRVAHNELKTIPPCVAKTPNLRILDVGYNKISDWGDLSALRELNRLEQLTLRGCPIANDPEYAEKITRMCPGLKLLDGRKPRDARGRPPERADATSDDELDDIDPEEKSKKRKKVKDSVKGRDGEKDDDGGGGESERSFVELFVAKNKGKVLDGDGAVATHEEEKDPTKRTGLIGVFENKDLKRKGPCGSAAFKALLKNDAGTGLNAGTWDEDDVTMQKTKKKKKEGTTDSTEKKKKKKKDLREMTPEERKEHLRMQRKRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S805</accession>
    <name>A4S805_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SDG3519</name>
        <name evidence="5" type="ORF">OSTLU_40473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421544.1">
        <property type="nucleotide sequence ID" value="XM_001421507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S805"/>
    <dbReference type="GeneID" id="5005783"/>
    <dbReference type="Gramene" id="ABO99837">
        <property type="protein sequence ID" value="ABO99837"/>
        <property type="gene ID" value="OSTLU_40473"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40473"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031250_0_0_1"/>
    <dbReference type="OMA" id="PHPPDLI"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF116">
        <property type="entry name" value="F21J9.27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="4">
        <location>
            <begin position="70"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="488" mass="53129" checksum="879E1DA6DB313038" modified="2007-05-15" version="1">MSDAPASSTAWWRRRELLATRTTTTTTTTATTTTTAEEERLANDAKARVQSGVLATFATWFDHRGGKIHERVRMTYRPNFGWSLEADGDIADGERLVSLPPKLMLRCDSDDVSEPLKNVVDRVPNEFWSSKVGLVLLRERVAGAHSAFAPYITLLPAVHEGSPTFFPPDAVRALEYAPIVQQINKRARFLGTFAGNALTVDDGESYVDEAHPGRQRVEMTIDANALGWATACASSRAFKVGANSAPAMLPVIDICNHSFNPSVSVRAIEEGDNAGGVELIARRALTSGEPIELSYGNLSNDELLLDYGFIVKDNPFDCVKLRWDLKLIELAREIGGLAAAPIDTVAKVAPWQATALERIGLVGDDPNVELSVFGAGQVMDKKALAGLRVLYSKSSAEASRAADAPFGEIDADVVSKDTEIKALRTCMSLLALALGNFSTTLEKDEELHDAATSPQVRLAIAFRMEKKKVLAKSMARLNESIERLQRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S828</accession>
    <name>A4S828_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-amylase</fullName>
            <ecNumber evidence="3">3.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">1,4-alpha-D-glucan glucanohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_18258</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421556.1">
        <property type="nucleotide sequence ID" value="XM_001421519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S828"/>
    <dbReference type="STRING" id="436017.A4S828"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="GeneID" id="5005660"/>
    <dbReference type="Gramene" id="ABO99849">
        <property type="protein sequence ID" value="ABO99849"/>
        <property type="gene ID" value="OSTLU_18258"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18258"/>
    <dbReference type="eggNOG" id="KOG0471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030069_1_0_1"/>
    <dbReference type="OMA" id="GWAVWEN"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11314">
        <property type="entry name" value="AmyAc_arch_bac_plant_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012850">
        <property type="entry name" value="A-amylase_bs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07821">
        <property type="entry name" value="Alpha-amyl_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="8">
        <location>
            <begin position="86"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO99849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="517" mass="58173" checksum="05C77DAF4394D8E1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4S859</accession>
    <name>A4S859_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_51525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the 19S regulatory particle (RP/PA700) lid subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700). The RP/PA700 complex is composed of at least 17 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p55 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421568.1">
        <property type="nucleotide sequence ID" value="XM_001421531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S859"/>
    <dbReference type="STRING" id="436017.A4S859"/>
    <dbReference type="GeneID" id="5005606"/>
    <dbReference type="Gramene" id="ABO99861">
        <property type="protein sequence ID" value="ABO99861"/>
        <property type="gene ID" value="OSTLU_51525"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51525"/>
    <dbReference type="eggNOG" id="KOG1498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033860_1_0_1"/>
    <dbReference type="OMA" id="AENEMFK"/>
    <dbReference type="OrthoDB" id="268763at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000070">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040896">
        <property type="entry name" value="RPN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18098">
        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="213"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00064920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="428" mass="48500" checksum="F216E77E7778F8A7" modified="2007-05-15" version="1">MLALEKTYRLAADFVATPRLCVAIVDVLRACEDWDGLREHVAALTKRRAQLKQAIAAMVRRCMEFIDEAPGAEQRLKLIETLCDATSGKIFVEVEKSRLTRALAKMHEDEGRVAEACGVMQEVAIETYGALTRHEKLFFIEEQVRLCLAKKDYLRALILSRKINPKVFDELIEKEKKDAEKAALAAKSATELSIPSLEALKLRYYELMVEYYSHSDEYLEQCRCYQNILECAEVKHDVARWGPTLKKVVWLVCLSKHEPMQQSILHGVKGNLKLSDLPAHEALIKQFCTKEIIHWTTLQERYAGEIAAETELFGGEKGAKRVEDLKLRVIEHNMLVIAAYYSRMSLSRLSELLCLSPEETEKHLSSCVVDKSVAAKIDRPAGLVNFSAAKSSDFLLNKWVSNIDSLLTCLDKASHLIQKESQQFKVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8X0</accession>
    <name>A4S8X0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421962.1">
        <property type="nucleotide sequence ID" value="XM_001421925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8X0"/>
    <dbReference type="GeneID" id="5006124"/>
    <dbReference type="Gramene" id="ABP00256">
        <property type="protein sequence ID" value="ABP00256"/>
        <property type="gene ID" value="OSTLU_27996"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27996"/>
    <dbReference type="HOGENOM" id="CLU_2324535_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="99" mass="10544" checksum="722338AD1972F216" modified="2007-05-15" version="1">MKEVEISAADKAFIESTKKTISAARAAGQVDAKTLKEIEAAAAGMKEVTKKVNTARMQKMEAALEAAIAAAKQCTDDCPAAWEEVEEISAAKSREEGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8Z4</accession>
    <name>A4S8Z4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_51641</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Ribosomal protein P0 is the functional equivalent of E.coli protein L10.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421843.1">
        <property type="nucleotide sequence ID" value="XM_001421806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8Z4"/>
    <dbReference type="STRING" id="436017.A4S8Z4"/>
    <dbReference type="GeneID" id="5005872"/>
    <dbReference type="Gramene" id="ABP00137">
        <property type="protein sequence ID" value="ABP00137"/>
        <property type="gene ID" value="OSTLU_51641"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_51641"/>
    <dbReference type="eggNOG" id="KOG0816">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071690_1_0_1"/>
    <dbReference type="OMA" id="LEWAENY"/>
    <dbReference type="OrthoDB" id="10262308at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000003">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="126"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="255" mass="28139" checksum="D4A260C432264145" modified="2007-05-15" version="1">MPKSKRAKVVSLTQTKKKDREWKSTLIERVRDALSERSSVYVFKYENMRNGTFKEMRAATEATTTFFVGSNKVLRVALGRDAESEASEGAATLGARVKGDCGVMFTNLSREDVESVFERFAVKDYARTGALARETVTVEAGPVHGPSGALMEHTLEPTLRKNGMPTKLNRGVIELEANHTLCKEGQHISPQGAILLRLFGHELAEFRCRLTCGLVNGELEVYEEDDEGDDGDDGPIDRFAHDGITDSMMLPPGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S942</accession>
    <name>A4S942_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TLDc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421869.1">
        <property type="nucleotide sequence ID" value="XM_001421832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S942"/>
    <dbReference type="STRING" id="436017.A4S942"/>
    <dbReference type="GeneID" id="5006039"/>
    <dbReference type="Gramene" id="ABP00163">
        <property type="protein sequence ID" value="ABP00163"/>
        <property type="gene ID" value="OSTLU_28070"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28070"/>
    <dbReference type="eggNOG" id="ENOG502S19X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1028888_0_0_1"/>
    <dbReference type="OMA" id="CAYDART"/>
    <dbReference type="OrthoDB" id="25620at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="1">
        <location>
            <begin position="28"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="25909" checksum="DDCE3B48B6B969F6" modified="2007-05-15" version="1">MNKDEWPDQWPAETTASAAALASDEGEVREIRPALKQTQLEKLALGCAYDARTHGWSARAFHTQLDGQGAAVLVGKTADGETFGGYNPIGWLGYGEARDAISAFLYVLDRKTGKAVKLPKTGGSGMAIIDEDGKGPQWGPDGLKISLEGRSARSRLGTYYETMPDGGDCMFANTKRGSPVELTELRVYVSLEDTEIAKNYQPNALQWQKGELEEIRSNDDDPNHMDGFFGKLFGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4S996</accession>
    <name>A4S996_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">YEATS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_28126</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421897.1">
        <property type="nucleotide sequence ID" value="XM_001421860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S996"/>
    <dbReference type="STRING" id="436017.A4S996"/>
    <dbReference type="GeneID" id="5006065"/>
    <dbReference type="Gramene" id="ABP00191">
        <property type="protein sequence ID" value="ABP00191"/>
        <property type="gene ID" value="OSTLU_28126"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28126"/>
    <dbReference type="eggNOG" id="KOG3149">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051385_1_1_1"/>
    <dbReference type="OMA" id="VMSEVYE"/>
    <dbReference type="OrthoDB" id="494822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16910">
        <property type="entry name" value="YEATS_TFIID14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573:SF1">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="YEATS" evidence="5">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="194" mass="22083" checksum="409B0797D4B1BE2F" modified="2007-05-15" version="1">MIVGTIAHYLGKRADEYHSHRWTVYVRGLDGEDLSHCVESVEFALHPSFDEPTRVLTQAPYEVTETGWGEFDIGVKITFSSDCGEARTVTTTTPLKLFPSAEEIARHGPQTTKKPLIKERYEEIVFHECDGGFYKRMKSHAWKRAPKSAHDDAWSSFKDKPELVGIYAAREVTKERIKILEQQLEVLESIDANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9B9</accession>
    <name>A4S9B9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L30, component of cytosolic 80S ribosome and 60S large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL30</name>
        <name evidence="5" type="ORF">OSTLU_37627</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421907.1">
        <property type="nucleotide sequence ID" value="XM_001421870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9B9"/>
    <dbReference type="STRING" id="436017.A4S9B9"/>
    <dbReference type="GeneID" id="5006078"/>
    <dbReference type="Gramene" id="ABP00201">
        <property type="protein sequence ID" value="ABP00201"/>
        <property type="gene ID" value="OSTLU_37627"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_37627"/>
    <dbReference type="eggNOG" id="KOG2988">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130502_0_1_1"/>
    <dbReference type="OMA" id="RSMPEQP"/>
    <dbReference type="OrthoDB" id="1928736at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="14"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="111" mass="12199" checksum="52EE796561A55013" modified="2007-05-15" version="1">MAPKQGSKKAAEGINARLQIVMRSGRYTLGYKQCLKTLRKGQSKLVLISNNCPALRKSEIEYYAMLAKTGVHHYAGNNVDLGTACGRYYRVSCMSITDPGDSDIVKAVPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9N7</accession>
    <name>A4S9N7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422203.1">
        <property type="nucleotide sequence ID" value="XM_001422166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9N7"/>
    <dbReference type="STRING" id="436017.A4S9N7"/>
    <dbReference type="GeneID" id="5006157"/>
    <dbReference type="Gramene" id="ABP00520">
        <property type="protein sequence ID" value="ABP00520"/>
        <property type="gene ID" value="OSTLU_18666"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18666"/>
    <dbReference type="HOGENOM" id="CLU_824856_0_0_1"/>
    <dbReference type="OrthoDB" id="10552237at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="FF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045148">
        <property type="entry name" value="TCRG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377">
        <property type="entry name" value="TRANSCRIPTION ELONGATION REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377:SF3">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="38325" checksum="73745C2529EBC9AF" modified="2007-05-15" version="1">MATAADAAGVVLDPDAYDDDATDGTRDDESSNFDAQWRRATTEKRADVEAFEAMVRARLGDGLADARWERALMKMRRDARFRALKTHSERRAAFDALRRRAAEEKREGEKRRRAARGEDEADADARRARALRARESEASERRRRDEREARFRKERLLDDEAEAAFQALCAERVKTYARSYDEAFRRDLVGDPMGRDDVSRLRGGEARARTLYEAHRLAVEASLKAEFEKLARRIIDKLVVRELSDETAANEARARRRASALDVIFDGALAYARAAEDEFELVDDVLFAFVSDGDKKQIWTECAIDILSRHGVKIGDDRVEDGEDEDEDEDEDGAVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAF2</accession>
    <name>A4SAF2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CDP-diacylglycerol--inositol 3-phosphatidyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_7533</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422375.1">
        <property type="nucleotide sequence ID" value="XM_001422338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAF2"/>
    <dbReference type="STRING" id="436017.A4SAF2"/>
    <dbReference type="GeneID" id="5006483"/>
    <dbReference type="Gramene" id="ABP00692">
        <property type="protein sequence ID" value="ABP00692"/>
        <property type="gene ID" value="OSTLU_7533"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7533"/>
    <dbReference type="eggNOG" id="KOG3240">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067602_2_1_1"/>
    <dbReference type="OMA" id="ASHWTHA"/>
    <dbReference type="OrthoDB" id="10251079at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABP00692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16947" checksum="EA50BB8FF40BE5BC" modified="2007-05-15" version="1" fragment="single">NVYAYAPNLVGYARIALAICALRTAFADVRTCLLCYFASFACDELDGRLARRYDQCSEFGRALDMITDRLATSGLLVVLAMEHREWYATCVGLLALDVASHWTHAYVQLMIGADGHKSIGDESFFLLRWYYGNRIFMGACCVSVEVLYLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAU6</accession>
    <name>A4SAU6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
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        <property type="nucleotide sequence ID" value="XM_001422464.1"/>
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    <dbReference type="Gramene" id="ABP00818">
        <property type="protein sequence ID" value="ABP00818"/>
        <property type="gene ID" value="OSTLU_29383"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29383"/>
    <dbReference type="eggNOG" id="ENOG502QUYC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040972_2_0_1"/>
    <dbReference type="OMA" id="MLWISKG"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03041">
        <property type="entry name" value="GST_N_2GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Glutathione_S-Trfase"/>
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        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45288">
        <property type="entry name" value="THIOREDOXIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45288:SF1">
        <property type="entry name" value="THIOREDOXIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01202">
        <property type="entry name" value="SUF2.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
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    </dbReference>
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        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="107"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="230"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="309" mass="34238" checksum="65E8EA0203DA8249" modified="2007-05-15" version="1">MREPTTTTTTPDATSEVIRVETRAEGEYELRQTTTPKRFAVADGELLNVATAAAPIALRWTSGLMCHGYEAKVVDGEVGEGEYAVWSGSGKAVRETSDVAKFPRPEKPLKMYQFQGCPFCKKVREAVISLDLDVIYYPCPRDGPEYREFVRAEGGRAQFPYLVDDNTGTKMYESDDIIAYMYEKYGPGKANIGPALTSGTLTSVTAGLALLPRLGKGSAYAPSKKPENMQPIVFYGYEGSPFCVLVAEKLCELELPYLQRSCGRGSPKRQELFDKRGTFQVPYIEDPNTGIAMFESKDIVNYLQEQYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAZ6</accession>
    <name>A4SAZ6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_19010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422527.1">
        <property type="nucleotide sequence ID" value="XM_001422490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAZ6"/>
    <dbReference type="STRING" id="436017.A4SAZ6"/>
    <dbReference type="GeneID" id="5006746"/>
    <dbReference type="Gramene" id="ABP00844">
        <property type="protein sequence ID" value="ABP00844"/>
        <property type="gene ID" value="OSTLU_19010"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19010"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019433_0_0_1"/>
    <dbReference type="OMA" id="VWDARQH"/>
    <dbReference type="OrthoDB" id="256303at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF7">
        <property type="entry name" value="F-BOX AND WD-40 DOMAIN PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="471"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="557"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="169"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="330"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABP00844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="794" mass="84376" checksum="AA8DE90FF8CC0D09" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB73</accession>
    <name>A4SB73_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422567.1">
        <property type="nucleotide sequence ID" value="XM_001422530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB73"/>
    <dbReference type="STRING" id="436017.A4SB73"/>
    <dbReference type="GeneID" id="5006625"/>
    <dbReference type="Gramene" id="ABP00884">
        <property type="protein sequence ID" value="ABP00884"/>
        <property type="gene ID" value="OSTLU_29509"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29509"/>
    <dbReference type="eggNOG" id="ENOG502QSHF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1083339_0_0_1"/>
    <dbReference type="OrthoDB" id="515493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044818">
        <property type="entry name" value="ILR3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46133">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46133:SF8">
        <property type="entry name" value="TRANSCRIPTION FACTOR ILR3-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="100"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP00884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="257" mass="27569" checksum="141FF9E8CA25D430" modified="2007-05-15" version="1">MDGATPTADWLSDFFDSFDADDVGAFDGANAFADVPTEVIGGEGPRVRAAGTKRKATEEADGSQDERVAVTATSVAATSVAATTAAATTATGRSNVLSEGAKKTKSTREKRRRDVLNSRFEELSAVLEPGESQGESQSKATVVFAATELIKRLRVEHARLANMIMRFQEDNLLKTELTQKLAAERDQLMQEKTHLLREKLRIEAQLQGFLTSMPFASPADGMVSTKSASGVAAWTVPMPFMPASEEGEDVTLRAPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4SB81</accession>
    <name>A4SB81_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="3 8">2.5.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_43874</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:21257"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EPSP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="3 8"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422572.1">
        <property type="nucleotide sequence ID" value="XM_001422535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SB81"/>
    <dbReference type="STRING" id="436017.A4SB81"/>
    <dbReference type="GeneID" id="5006630"/>
    <dbReference type="Gramene" id="ABP00889">
        <property type="protein sequence ID" value="ABP00889"/>
        <property type="gene ID" value="OSTLU_43874"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43874"/>
    <dbReference type="eggNOG" id="KOG0692">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024321_0_0_1"/>
    <dbReference type="OMA" id="YEDHRMA"/>
    <dbReference type="OrthoDB" id="197068at2759"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.65.10.10:FF:000004">
        <property type="entry name" value="3-phosphoshikimate 1-carboxyvinyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="entry name" value="Enolpyruvate transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090">
        <property type="entry name" value="AROM/DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090:SF5">
        <property type="entry name" value="PENTAFUNCTIONAL AROM POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Enolpyruvate transferase" evidence="9">
        <location>
            <begin position="7"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABP00889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="436" mass="46403" checksum="2C3131C2E5EC964E" modified="2007-05-15" version="1">MEQLTLKPMKKIEGTVRLPGSKSLSNRILLLAALAEGTTKVENLLDSDDIRYMVDALKVLGLSFTEDRENNILEITGCGGKLPVEGAELFLGNAGTAMRPLTAAVAAAGKGTFILDGVERMRERPIQDLVDGLVQLGVKAECTMGTGCPPVKVEANGLPGGRVELSGSVSSQYLTALLMAAPLCEGSIEIVIVDELISKPYVEMTITLMERFGVKVEKADDLQSFKIQGGQKYISPGSAFVEGDASSASYFLAGATITGGTVTVIGCGSESIQGDTNFAYTMEQMGATLEWGPNSVTCTGPKGPLKAIDVNMNAMPDAAMTLAVAALFADGITTIRDVASWRVKETERMIAICTELRKLGCDVFEGADYCVITPPHKLDPPAKMKANVDIDTYDDHRMAMAFALAACGDVDVVINDPKCTKKTFPTYFDVLKSVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBA7</accession>
    <name>A4SBA7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422586.1">
        <property type="nucleotide sequence ID" value="XM_001422549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBA7"/>
    <dbReference type="GeneID" id="5006644"/>
    <dbReference type="Gramene" id="ABP00903">
        <property type="protein sequence ID" value="ABP00903"/>
        <property type="gene ID" value="OSTLU_29542"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29542"/>
    <dbReference type="HOGENOM" id="CLU_2214387_0_0_1"/>
    <dbReference type="OrthoDB" id="10459387at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11234" checksum="2671E29A4F0D71EA" modified="2007-05-15" version="1">MARALADRALGAVRVTCSVRGLDAVARAHGSALASCDVVDRDLPRPVRCADDDESRAATSRADAVARERAVVSASDAPLYARRKWKAPMRLDVEVGASLGDIESASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4SBC1</accession>
    <name>A4SBC1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_29556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP01066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422749.1">
        <property type="nucleotide sequence ID" value="XM_001422712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SBC1"/>
    <dbReference type="STRING" id="436017.A4SBC1"/>
    <dbReference type="GeneID" id="5006650"/>
    <dbReference type="Gramene" id="ABP01066">
        <property type="protein sequence ID" value="ABP01066"/>
        <property type="gene ID" value="OSTLU_29556"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29556"/>
    <dbReference type="eggNOG" id="KOG2163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457418_0_0_1"/>
    <dbReference type="OMA" id="CHHLANR"/>
    <dbReference type="OrthoDB" id="515817at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048343">
        <property type="entry name" value="ZW10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20666">
        <property type="entry name" value="ZW10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centromere/kinetochore protein zw10 C-terminal" evidence="2">
        <location>
            <begin position="299"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="3">
        <location>
            <begin position="448"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABP01066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="597" mass="63869" checksum="7C5BBB205FF2AE3F" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQG8</accession>
    <name>A4RQG8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyanobacterial aminoacyl-tRNA synthetase CAAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_8449</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415730.1">
        <property type="nucleotide sequence ID" value="XM_001415693.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQG8"/>
    <dbReference type="STRING" id="436017.A4RQG8"/>
    <dbReference type="GeneID" id="4999861"/>
    <dbReference type="Gramene" id="ABO94022">
        <property type="protein sequence ID" value="ABO94022"/>
        <property type="gene ID" value="OSTLU_8449"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8449"/>
    <dbReference type="eggNOG" id="ENOG502QWJR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095488_4_0_1"/>
    <dbReference type="OMA" id="ESQWAKV"/>
    <dbReference type="OrthoDB" id="2014299at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025564">
        <property type="entry name" value="CAAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033344">
        <property type="entry name" value="CURT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222:SF3">
        <property type="entry name" value="PROTEIN CURVATURE THYLAKOID 1C, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14159">
        <property type="entry name" value="CAAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanobacterial aminoacyl-tRNA synthetase CAAD" evidence="3">
        <location>
            <begin position="8"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO94022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="90" mass="9997" checksum="DBEBFA8D7552B245" modified="2007-05-15" version="1" fragment="single">KLREVTDTLSEKWEESDEKPAIVTLSVYGFVGLVAANGTLRAVDSLPLIPDLLELVGILFSGFFVYQNLLYKPDRAALKETVTKTLNKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQT9</accession>
    <name>A4RQT9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_28777</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415444.1">
        <property type="nucleotide sequence ID" value="XM_001415407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQT9"/>
    <dbReference type="STRING" id="436017.A4RQT9"/>
    <dbReference type="GeneID" id="4999587"/>
    <dbReference type="Gramene" id="ABO93736">
        <property type="protein sequence ID" value="ABO93736"/>
        <property type="gene ID" value="OSTLU_28777"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28777"/>
    <dbReference type="eggNOG" id="KOG3448">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130474_0_1_1"/>
    <dbReference type="OMA" id="DNISCTD"/>
    <dbReference type="OrthoDB" id="10256176at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01725">
        <property type="entry name" value="LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000009">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016654">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829">
        <property type="entry name" value="SNRNP CORE PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829:SF2">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="9">
        <location>
            <begin position="39"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO93736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="130" mass="14607" checksum="8AF8545686B08592" modified="2007-05-15" version="1">MSPSRVVPLTFARGAIEKIAKSRSRRADVKSTRVLDVALFYSYFKTLVGKPVTVELKNDLAIAGTLVSVDQYLNIKLENTRVTDEARYPHMRSVRNCFIRGSVVRYVQLPEAAVDVDILHDATRREARGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQZ8</accession>
    <name>A4RQZ8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 8 central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_86096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415479.1">
        <property type="nucleotide sequence ID" value="XM_001415442.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RQZ8"/>
    <dbReference type="GeneID" id="4999734"/>
    <dbReference type="Gramene" id="ABO93771">
        <property type="protein sequence ID" value="ABO93771"/>
        <property type="gene ID" value="OSTLU_86096"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86096"/>
    <dbReference type="eggNOG" id="KOG2079">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000917_1_2_1"/>
    <dbReference type="OMA" id="NAAVHYV"/>
    <dbReference type="OrthoDB" id="289913at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="4">
        <location>
            <begin position="641"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO93771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1363" mass="149102" checksum="56297D4455EDBB49" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRX2</accession>
    <name>A4RRX2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ALA-interacting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_44624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415978.1">
        <property type="nucleotide sequence ID" value="XM_001415941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRX2"/>
    <dbReference type="STRING" id="436017.A4RRX2"/>
    <dbReference type="GeneID" id="4999396"/>
    <dbReference type="Gramene" id="ABO94270">
        <property type="protein sequence ID" value="ABO94270"/>
        <property type="gene ID" value="OSTLU_44624"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_44624"/>
    <dbReference type="eggNOG" id="KOG2952">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025025_1_1_1"/>
    <dbReference type="OMA" id="WWTDTNV"/>
    <dbReference type="OrthoDB" id="340608at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015840">
        <property type="entry name" value="DUF284_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="333" mass="36077" checksum="C294C7CB98B596C4" modified="2007-05-15" version="1">MAGAARTTAPTSRKPAFSAFSQQQLWARRPALTPALTAKLMISIGVACFAVGAAIFNTANDLRTLVKRYDDAATCASGFFPTSAEQAMQMSFNGAGTTCTVTLTAKSNMNKPVYVYYELSNFFQNHRAFVRDLDYFQLMGKPSQGLCTTHEKTSAGAEISPCGVQAWSFFNDSYAVAVNGAATTIDSANIAWKSDLKYKLGDYAPTNMNTDQATRGGGQITGNVDTDEDFATWMRTAALSKFRKLVGVINADIAKGDTITFTIQNRYNTYKFNGEKAVVLATNSWIGGRNLVFPACYFLAGSLCSGLGAVGVFLHIFGDKFKSESTNEWSTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRY0</accession>
    <name>A4RRY0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_29176</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFB7 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415983.1">
        <property type="nucleotide sequence ID" value="XM_001415946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRY0"/>
    <dbReference type="STRING" id="436017.A4RRY0"/>
    <dbReference type="GeneID" id="4999859"/>
    <dbReference type="Gramene" id="ABO94275">
        <property type="protein sequence ID" value="ABO94275"/>
        <property type="gene ID" value="OSTLU_29176"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29176"/>
    <dbReference type="eggNOG" id="KOG3468">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154847_3_0_1"/>
    <dbReference type="OMA" id="HELHAYN"/>
    <dbReference type="OrthoDB" id="268414at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008698">
        <property type="entry name" value="NDUB7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900">
        <property type="entry name" value="NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05676">
        <property type="entry name" value="NDUF_B7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO94275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="80" mass="9415" checksum="7CAEA9F1EA9CA4A6" modified="2007-05-15" version="1">MGSSDQSEMIASREDMKRAKLDIGYRDFCAHLLIPLNECRRKSFYLPWKCGHERHVYEKCQYKEYMKRVASVKASKGDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS13</accession>
    <name>A4RS13_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 8">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CAH1</name>
        <name evidence="9" type="ORF">OSTLU_8182</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 8"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415659.1">
        <property type="nucleotide sequence ID" value="XM_001415622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS13"/>
    <dbReference type="STRING" id="436017.A4RS13"/>
    <dbReference type="GeneID" id="4999520"/>
    <dbReference type="Gramene" id="ABO93951">
        <property type="protein sequence ID" value="ABO93951"/>
        <property type="gene ID" value="OSTLU_8182"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_8182"/>
    <dbReference type="eggNOG" id="KOG1578">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053879_5_3_1"/>
    <dbReference type="OMA" id="QCESCAR"/>
    <dbReference type="OrthoDB" id="10248475at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF76">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO93951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="19746" checksum="AB62BFB3D4EDBB20" modified="2007-05-15" version="1" fragment="single">RGQNPRALVVACCDSRADPAIVFDTAPGDVFVVRNVANLVPPYTGVDFGHHGTCAAVEYSVAHLEVPLIVVMGHTQCGGAAAGLRKYGGDPNGDPAVFAANEATGEGFIGSWVALTKTSVREVCEKYDPDIRARMLEHELVRNSVRNLATFPFVRERMDKGTLEVIGAVFNVFDGTLTILDAETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS56</accession>
    <name>A4RS56_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">riboflavin kinase</fullName>
            <ecNumber evidence="2">2.7.1.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_9092</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="2"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415682.1">
        <property type="nucleotide sequence ID" value="XM_001415645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS56"/>
    <dbReference type="STRING" id="436017.A4RS56"/>
    <dbReference type="GeneID" id="5000019"/>
    <dbReference type="Gramene" id="ABO93974">
        <property type="protein sequence ID" value="ABO93974"/>
        <property type="gene ID" value="OSTLU_9092"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_9092"/>
    <dbReference type="eggNOG" id="KOG3110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048437_3_3_1"/>
    <dbReference type="OMA" id="NGEVHKM"/>
    <dbReference type="OrthoDB" id="276388at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO93974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="126" mass="13695" checksum="A85BD1C290188FC7" modified="2007-05-15" version="1" fragment="single">VVTGFGRGSKQMGVPTANLDPETCGGEAVLSALPLGVYFGWAKREGESNWHECVLNVGKRPTFVDGDGTTIEVHVMGASDATPEYEDDFYGETMRVDVCGFIRPELRFDSLPELVARIKTDIGLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS83</accession>
    <name>A4RS83_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001415995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS83"/>
    <dbReference type="STRING" id="436017.A4RS83"/>
    <dbReference type="GeneID" id="4999513"/>
    <dbReference type="Gramene" id="ABO94324">
        <property type="protein sequence ID" value="ABO94324"/>
        <property type="gene ID" value="OSTLU_29278"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29278"/>
    <dbReference type="eggNOG" id="ENOG502QWDD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061989_0_0_1"/>
    <dbReference type="OMA" id="WKNGQYK"/>
    <dbReference type="OrthoDB" id="10267106at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033194">
        <property type="term" value="P:response to hydroperoxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="UPF0246"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YaaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30283:SF4">
        <property type="entry name" value="PEROXIDE STRESS RESISTANCE PROTEIN YAAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30283">
        <property type="entry name" value="PEROXIDE STRESS RESPONSE PROTEIN YAAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03883">
        <property type="entry name" value="H2O2_YaaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="294" mass="31781" checksum="8E7CCD418012FA3F" modified="2007-05-15" version="1">MKATTTREDASASASASATPFVVVLSPAKALDEAAMNASDATRATRPRFAERANAIAREARELKAGDLKTLMGVSDAIAKLNVERFGNFEKAATKACALAFDGPAFRHLKASTLKTEEEKAYLQKHLRILSGLYGCLRPYDAIAPYRLEMGTKWAPSGKDLYAYWGEDIALAIADDLDEQAATSGESSARPFVVNCASQEYWKSVKREALTKRGVDVYTMTFPGPAVYAKQARGAMVRHCVDARVASPEDLKTFRGTDGCWKFDAAASSEFNFVFARGAVKAGDAKPAKKAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS94</accession>
    <name>A4RS94_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_1953</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001416000.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="olu:OSTLU_1953"/>
    <dbReference type="eggNOG" id="ENOG502QQ4X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022515_2_0_1"/>
    <dbReference type="OMA" id="FEVRQWD"/>
    <dbReference type="OrthoDB" id="496493at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="R3H_AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058670">
        <property type="entry name" value="PTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034081">
        <property type="entry name" value="R3H_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045735">
        <property type="entry name" value="Spore_III_AA_AAA+_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20953">
        <property type="entry name" value="KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20953:SF3">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25516">
        <property type="entry name" value="PTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19568">
        <property type="entry name" value="Spore_III_AA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="120"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="552" mass="59822" checksum="37094E50E3681A7A" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSW8</accession>
    <name>A4RSW8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Potassium:hydrogen antiporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Kea1</name>
        <name evidence="12" type="ORF">OSTLU_119547</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416419.1">
        <property type="nucleotide sequence ID" value="XM_001416382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSW8"/>
    <dbReference type="GeneID" id="5000472"/>
    <dbReference type="Gramene" id="ABO94712">
        <property type="protein sequence ID" value="ABO94712"/>
        <property type="gene ID" value="OSTLU_119547"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119547"/>
    <dbReference type="eggNOG" id="KOG1650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005126_11_1_1"/>
    <dbReference type="OMA" id="VREESAY"/>
    <dbReference type="OrthoDB" id="1654420at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045158">
        <property type="entry name" value="KEA4/5/6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16254">
        <property type="entry name" value="POTASSIUM/PROTON ANTIPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16254:SF14">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="537"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="622"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="286"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="148"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="159"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO94712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="671" mass="73041" checksum="ABCBFC3B671A6791" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT91</accession>
    <name>A4RT91_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 4 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">26S proteasome regulatory subunit RPN10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_6757</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S5A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416354.1">
        <property type="nucleotide sequence ID" value="XM_001416317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT91"/>
    <dbReference type="STRING" id="436017.A4RT91"/>
    <dbReference type="GeneID" id="5000429"/>
    <dbReference type="Gramene" id="ABO94647">
        <property type="protein sequence ID" value="ABO94647"/>
        <property type="gene ID" value="OSTLU_6757"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_6757"/>
    <dbReference type="eggNOG" id="KOG2884">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033293_1_0_1"/>
    <dbReference type="OMA" id="QCIPENT"/>
    <dbReference type="OrthoDB" id="1731724at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010150">
        <property type="term" value="P:leaf senescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048528">
        <property type="term" value="P:post-embryonic root development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010029">
        <property type="term" value="P:regulation of seed germination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009733">
        <property type="term" value="P:response to auxin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009735">
        <property type="term" value="P:response to cytokinin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051788">
        <property type="term" value="P:response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009744">
        <property type="term" value="P:response to sucrose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048767">
        <property type="term" value="P:root hair elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000005">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="5"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00071116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="246" mass="25997" checksum="1DE1B35E82BDB98B" modified="2007-05-15" version="1" fragment="single">MVLEATILCLDNSEHVRNSDYAPSRLQAEADALNLLAGAKTQSNPENAVGVLSLAGKTPRVLTTPTQDLGAVLNSVHGVKIEGEINVCVGVQVAHLALKHRQNKHQRMRIVLFVGSPLRDEIEALRAVGKKLRKCNVAVDVVSFGDVEANREKLDAFVTSVNKNNNSNLVVVEPGANLSDVLCGTAIFNQDGAASGSGFAAAAAAAQSQAAMQGLEGMGDMGDMGDDPALMMALRISLEEERARQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTI8</accession>
    <name>A4RTI8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RWP-RK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29862</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative transcription factor.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416067.1">
        <property type="nucleotide sequence ID" value="XM_001416030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTI8"/>
    <dbReference type="STRING" id="436017.A4RTI8"/>
    <dbReference type="GeneID" id="5000357"/>
    <dbReference type="Gramene" id="ABO94359">
        <property type="protein sequence ID" value="ABO94359"/>
        <property type="gene ID" value="OSTLU_29862"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29862"/>
    <dbReference type="eggNOG" id="ENOG502QSPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028507_0_0_1"/>
    <dbReference type="OMA" id="NHKARRN"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044607">
        <property type="entry name" value="RKD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373">
        <property type="entry name" value="PROTEIN RKD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373:SF2">
        <property type="entry name" value="RWP-RK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="8">
        <location>
            <begin position="122"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="297"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="423"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO94359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="644" mass="68653" checksum="F736741879213B73" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTY7</accession>
    <name>A4RTY7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_4650</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416867.1">
        <property type="nucleotide sequence ID" value="XM_001416830.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RTY7"/>
    <dbReference type="STRING" id="436017.A4RTY7"/>
    <dbReference type="GeneID" id="5001051"/>
    <dbReference type="Gramene" id="ABO95160">
        <property type="protein sequence ID" value="ABO95160"/>
        <property type="gene ID" value="OSTLU_4650"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4650"/>
    <dbReference type="eggNOG" id="KOG1528">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033446_3_0_1"/>
    <dbReference type="OMA" id="WSSHVRY"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000003">
        <property type="entry name" value="PAP-specific phosphatase HAL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF17">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO95160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="366" mass="39173" checksum="3DF99329B576BABD" modified="2007-05-15" version="1" fragment="single">ELETALDAVRLASTLCQEVQAQLMRMDEQAETKEDRSLVTLADYAAQAIIVWRISQDFPDMTLVGEEDAEALTEGGEGGAATLAKIVALVNKTLKTHIGDDAVELSSQDVVSAINKGKSTGGAKGKHWILDPVDGTLGFVRGDQYAIALALMDEGDLKVGVMGCPNMPKQGDVLEFETSYSYGFSPRLVSKMLAGDSLGWYKGCIFTAVRGHGSYMFPVDEELNFEPSKVTVSGAFDPQKAKFTEPVMKANSSQGFTAAVATNLGIECKPLRIYSQVKYGSVARADADVFMKFPKAGYREKIWDHAAGVILVEEAGGRVSDAGGAPLNFAGGRYIEGLDRGIIAASSALHERLLDAVAKSWSSSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4RU87</accession>
    <name>A4RU87_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">rRNA-processing protein FYV7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_30534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416916.1">
        <property type="nucleotide sequence ID" value="XM_001416879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RU87"/>
    <dbReference type="GeneID" id="5001090"/>
    <dbReference type="Gramene" id="ABO95209">
        <property type="protein sequence ID" value="ABO95209"/>
        <property type="gene ID" value="OSTLU_30534"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30534"/>
    <dbReference type="HOGENOM" id="CLU_1231374_0_0_1"/>
    <dbReference type="OMA" id="RFIKARQ"/>
    <dbReference type="OrthoDB" id="515882at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013730">
        <property type="entry name" value="Fyv7/TAP26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15657">
        <property type="entry name" value="THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15657:SF1">
        <property type="entry name" value="THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08524">
        <property type="entry name" value="rRNA_processing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO95209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="23273" checksum="1B61E8A949649E51" modified="2007-05-15" version="1">MKRDGRSALSIGRFINARKSTYDKRARIKQSRDEAAAKKAKYERLQKKLGEKIERDEGFDPEAYERRLAAIDNPDLAREAKGAKRGDDEDEDLDEDAKTRAAAAEDDEAPEEQLTVKGKKKKFDYLKKAWEKGQVERAEREAQRKVFLEEKAARDAELKAQRVKRQDKKQLMRKKTKRGQPVMKHRVQSILDKLQAEQMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUB4</accession>
    <name>A4RUB4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_30562</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416931.1">
        <property type="nucleotide sequence ID" value="XM_001416894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUB4"/>
    <dbReference type="STRING" id="436017.A4RUB4"/>
    <dbReference type="GeneID" id="5000690"/>
    <dbReference type="Gramene" id="ABO95224">
        <property type="protein sequence ID" value="ABO95224"/>
        <property type="gene ID" value="OSTLU_30562"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30562"/>
    <dbReference type="eggNOG" id="KOG0344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_4_1"/>
    <dbReference type="OMA" id="EMAHSIM"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17957">
        <property type="entry name" value="DEADc_DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044764">
        <property type="entry name" value="DDX52/Rok1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="56"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="252"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="393"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO95224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="474" mass="52785" checksum="B1EB1B4960400E77" modified="2007-05-15" version="1">MRKRLKMRVQGADGACPAPLQGFEELHERYKCGRRLLERMREANFKEPTPIQRQAVPILCSGSELLAIAPTGSGKTLAFLLPIIMKLGTHEEGGARALLLAPTKELAGQSARILRILSRGVSGLKSCLLTKATAGNDFSKVDIVVATPMRLKILLQHDKIDLSKVLYLVLDEADKLFEMGFVEQIDAVVAACDNKDVTRALFSATLPEKVEELARSVMARPIRLTVGERNSASNTISQRMVFCGHEAGKLLALRQIIREGIKPPVIIFTQSKERAKHLAKELTGDGLHIGLIHAEMSDSKREEQVDRFRMGETWVLIATDLMARGMDFVGVSTVINFDFPGSPTSYIHRIGRSGRAGRPGAAITFFTEEDAQRGDLKPIANVMKNSGCEVPEWMLNHTGEKGLRRRKRKDGKEDNPRRAPLDMPMGADPKVYAPDKKKRKKTPRKKNDDEAMPPLPKKWKGKSKSKEKKEKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUC2</accession>
    <name>A4RUC2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_34527</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416935.1">
        <property type="nucleotide sequence ID" value="XM_001416898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUC2"/>
    <dbReference type="STRING" id="436017.A4RUC2"/>
    <dbReference type="GeneID" id="5000710"/>
    <dbReference type="Gramene" id="ABO95228">
        <property type="protein sequence ID" value="ABO95228"/>
        <property type="gene ID" value="OSTLU_34527"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34527"/>
    <dbReference type="eggNOG" id="KOG2241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_6_5_1"/>
    <dbReference type="OMA" id="YVEMVEC"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000225">
        <property type="entry name" value="tyrosine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF47">
        <property type="entry name" value="NUCLEIC ACID-BINDING, OB-FOLD-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO95228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="161" mass="17203" checksum="9C68F92A14A1C70B" modified="2007-05-15" version="1">MELKVGKVLSVENHPESEKLYVEMVECGEDEPRLICSGLAPYMSKDDVLGKLVIVVANLKPRNMAGMKSNGMLLAASDAAHENVELLCAPEGAVPGERITWDGAENIEPHGVNKVAKKKIWEGVQKDLKTDATKGANWNGLPMLTSAGQCTCASLTDANVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUH8</accession>
    <name>A4RUH8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_14631</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the V-ATPase G subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416673.1">
        <property type="nucleotide sequence ID" value="XM_001416636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUH8"/>
    <dbReference type="STRING" id="436017.A4RUH8"/>
    <dbReference type="GeneID" id="5000658"/>
    <dbReference type="Gramene" id="ABO94966">
        <property type="protein sequence ID" value="ABO94966"/>
        <property type="gene ID" value="OSTLU_14631"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14631"/>
    <dbReference type="eggNOG" id="KOG1772">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125101_3_0_1"/>
    <dbReference type="OMA" id="ARKYRQD"/>
    <dbReference type="OrthoDB" id="250802at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005124">
        <property type="entry name" value="V-ATPase_G"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01147">
        <property type="entry name" value="V_ATP_synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713:SF11">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="30"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="107" mass="11726" checksum="AD20D42C1D4C01EB" modified="2007-05-15" version="1">MDASRDGISKLMLAEKEAQAIVSAAREEKTARLRAAVEEAKGEIAAYRAEREARYARMVAEQTGNKAETDSRLKAEYDEEMAKLQAKVSAAKSTVVHDLLSAVKDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUM9</accession>
    <name>A4RUM9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO94992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416699.1">
        <property type="nucleotide sequence ID" value="XM_001416662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUM9"/>
    <dbReference type="GeneID" id="5000699"/>
    <dbReference type="Gramene" id="ABO94992">
        <property type="protein sequence ID" value="ABO94992"/>
        <property type="gene ID" value="OSTLU_30676"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30676"/>
    <dbReference type="HOGENOM" id="CLU_1941613_0_0_1"/>
    <dbReference type="OrthoDB" id="10438621at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="130" mass="14708" checksum="CAE7EF3CE8876012" modified="2007-05-15" version="1">MEEAVAALARGERALGEKNAKAAIEALSKIETLVPREYKLNQRAGLLLSEAYKLAGDNARYLEYKNRVWWWGRGLRWPGWYIIAYLSARSAYFDAKEDDEAAFSMSEAGVVAPLWVGLLFLLVEYGLPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4RUT0</accession>
    <name>A4RUT0_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_24271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416725.1">
        <property type="nucleotide sequence ID" value="XM_001416688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RUT0"/>
    <dbReference type="GeneID" id="5000904"/>
    <dbReference type="Gramene" id="ABO95018">
        <property type="protein sequence ID" value="ABO95018"/>
        <property type="gene ID" value="OSTLU_24271"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_24271"/>
    <dbReference type="HOGENOM" id="CLU_022051_0_0_1"/>
    <dbReference type="OMA" id="TWAARAN"/>
    <dbReference type="OrthoDB" id="10505494at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="694" mass="77982" checksum="FB73F12076A99E02" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV28</accession>
    <name>A4RV28_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RecA family profile 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_86836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416770.1">
        <property type="nucleotide sequence ID" value="XM_001416733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV28"/>
    <dbReference type="STRING" id="436017.A4RV28"/>
    <dbReference type="GeneID" id="5000648"/>
    <dbReference type="Gramene" id="ABO95063">
        <property type="protein sequence ID" value="ABO95063"/>
        <property type="gene ID" value="OSTLU_86836"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_86836"/>
    <dbReference type="eggNOG" id="KOG1564">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041732_1_0_1"/>
    <dbReference type="OrthoDB" id="1861185at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071140">
        <property type="term" value="P:resolution of mitotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090656">
        <property type="term" value="P:t-circle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="1">
        <location>
            <begin position="12"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="307" mass="31987" checksum="2942E3AD98C57CB4" modified="2007-05-15" version="1">MRVAAAAAADARAACVSTMCPRIDDALRGGVRARHVTEIAGESASAKTTLCAQLAVRATARGGAAVYVHTDGPAPTALMRRIASSARFVAEACDGDEDAATAALERVYVVKALGDADALRETLTAVSAVLRAPVSEDAVVRMIVVDSIAAPFRDDATNGGWTYAAKRAGALHKLTMLLKEYATKHDVAVVVTNHVVDSVRENGTGAHGDGAVATRAMGEFTTSGRRVVPALGLMWSNCVNARLFLTRRATRGQGYVVGGDDGDDGNAGVARTLHVVYAPHLPESSVDFVVREDGAWDVAAPRPRAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV79</accession>
    <name>A4RV79_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UNC-45/Cro1/She4 central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_30877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417091.1">
        <property type="nucleotide sequence ID" value="XM_001417054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV79"/>
    <dbReference type="STRING" id="436017.A4RV79"/>
    <dbReference type="GeneID" id="5001011"/>
    <dbReference type="Gramene" id="ABO95384">
        <property type="protein sequence ID" value="ABO95384"/>
        <property type="gene ID" value="OSTLU_30877"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30877"/>
    <dbReference type="HOGENOM" id="CLU_571552_0_0_1"/>
    <dbReference type="OMA" id="MAEMQLV"/>
    <dbReference type="OrthoDB" id="565708at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46043">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46043:SF13">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO95384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="50513" checksum="31AE86170B71F1B4" modified="2007-05-15" version="1">MTDAKVHAMMDDIAGWKRSTGKMRRLLRQMRALRAAIAGEVETTWGKLTHRTRGTFLRESLPRLCEFKEREAQIAAFGLVQTLALHDDCATALATKEMFKLCVATIKGKDKERAVAASGALTTLVNHDDTRFLASDEGLDKSMTALITEKGLGVRVKRNCVVTFARIADDPEVASLMSAKAPEQLIKNFLDFVDKTDDTDTEKWALIAIARLAMNDEFSNLMEKKGYVPFLFELSRDKIPARKLAAALVIAHMARNKDLRETLVKYRAIQLFCTIAMNTSERIDMAEMQLVAALGLKNLASNFDLRALAGKTGAIQACIFMLRSPQQEVKRFAALAIAELALYEPNGERFCKQGALKWIIQLARTGDVRSETAAITALSNLMLSPGNQSIMIVEDGTKVVDYLQNSRNPRVAHLAKQLLKRLRMAKLRAACKFAARMKATGNALIDAGIEIGEGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A4RV82</accession>
    <name>A4RV82_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000583">
        <property type="protein sequence ID" value="ABO95386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417093.1">
        <property type="nucleotide sequence ID" value="XM_001417056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RV82"/>
    <dbReference type="GeneID" id="5000805"/>
    <dbReference type="Gramene" id="ABO95386">
        <property type="protein sequence ID" value="ABO95386"/>
        <property type="gene ID" value="OSTLU_30880"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30880"/>
    <dbReference type="HOGENOM" id="CLU_781650_0_0_1"/>
    <dbReference type="OMA" id="MTHIGVE"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="38795" checksum="5E8DDC43A8AD0FAB" modified="2007-05-15" version="1">MASVRRAPSTATPRASSRRARDARSTPRRARVSPRALDAARDVVVVTGALERLAQTSAVELKRNEKSSDVRVVAALPREAFEGVRNPRDVRSTTLVYPHAKTLEMLDEQGVETAELGETLGGETATRERTTCVIFAEESSKKLKACVETFCEAIDGGRFPRLRRVVLMSRIGVERRDVDPFKYMNRKTFRGGAPLDDCVACEDMIRRRAAKTVKPGGVADGWTFTIVRTGELRGNGPTSKVVQADYALTLVDNAFDVRMQDIDIDEGDKMPGGDFTKRLSAAVFANRTLTTSRYDVLNAAYSIVSTGPAPRERRKGYDVAKGKSPPPVSDREIDEALAPGDEDAERVPGAVPVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWE7</accession>
    <name>A4RWE7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DMT family transporter: phosphate/phosphoenolpyruvate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_87077</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417565.1">
        <property type="nucleotide sequence ID" value="XM_001417528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWE7"/>
    <dbReference type="GeneID" id="5001233"/>
    <dbReference type="Gramene" id="ABO95858">
        <property type="protein sequence ID" value="ABO95858"/>
        <property type="gene ID" value="OSTLU_87077"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87077"/>
    <dbReference type="eggNOG" id="KOG1443">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022332_1_2_1"/>
    <dbReference type="OMA" id="DIENETC"/>
    <dbReference type="OrthoDB" id="18894at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="10"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO95858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="375" mass="41480" checksum="ADEC63C6083D8BCC" modified="2007-05-15" version="1">MRDVRARGLKCSLLVLVWFSTGTGLALFNKQILGVERGGFPCPIFLTSMQFAMQYAMARACLGAGVLEDAEKARGKREEVPSEVYWRNLAPVGAAMALDIALSNLSLAFITVSVYTVAKTSTIVFTLGLAFLFRFERPTWFLGGVVTLVVVGQVMSVEGDAQFDVFGFIMCLIAALMSALRWIFSQRVMHRDRDEPGDHAKGIKDSHHVSHPVVFVSLIYPIMFVIVFTFSSLKERWWFAIPHSKWLASPIDVFVDLVVFACGASMAFCLTLAEFELLNETSAMSMMFIGVLKDIINIVCGMLLFGDKFGSANVVGLGLCMVGVVGYNKYKWEQLKLKALTSQRRGDDSDAVPLVEITSISSTSPRRRLDDFTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWL7</accession>
    <name>A4RWL7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000584">
        <property type="protein sequence ID" value="ABO95893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417600.1">
        <property type="nucleotide sequence ID" value="XM_001417563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWL7"/>
    <dbReference type="STRING" id="436017.A4RWL7"/>
    <dbReference type="GeneID" id="5001541"/>
    <dbReference type="Gramene" id="ABO95893">
        <property type="protein sequence ID" value="ABO95893"/>
        <property type="gene ID" value="OSTLU_31380"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31380"/>
    <dbReference type="eggNOG" id="ENOG502S77H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1002530_0_0_1"/>
    <dbReference type="OrthoDB" id="498126at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO95893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="278" mass="30602" checksum="9621010AE3C5192C" modified="2007-05-15" version="1">MIGALVGRRKTTGERVTLKAFSGQLFGEWRVEGWAPPVGELTHDTAYYKSEHGKIKALSERIAKAEMEERMTRAEVREATAARDDEAKALAAEAKRAKEARRRARADGASDAIVETLDEESRASKRAMSTLKKARDAAVAPKLEILARLRARIDDMKSERKALSRALQDKIWEGYKLPSLGGQVRPLRDVFHPPVAALPCGCADCAAPKLLAWAHTLGITPTSIAEIWIGASRPRDFRVRGVAYGACRDKCVPIMGHMLCPEPPDARSVDATTPCRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RWZ9</accession>
    <name>A4RWZ9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">OSTLU_31514</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417910.1">
        <property type="nucleotide sequence ID" value="XM_001417873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RWZ9"/>
    <dbReference type="STRING" id="436017.A4RWZ9"/>
    <dbReference type="GeneID" id="5002075"/>
    <dbReference type="Gramene" id="ABO96203">
        <property type="protein sequence ID" value="ABO96203"/>
        <property type="gene ID" value="OSTLU_31514"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31514"/>
    <dbReference type="eggNOG" id="KOG0682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_0_1"/>
    <dbReference type="OMA" id="HATMTSI"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="9"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO96203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="418" mass="44655" checksum="9B2259145D3C3E1C" modified="2007-05-15" version="1">MAIDAGTTAFMIVSMALVNLMTPGLAFFYGGLVRSSNVLTIMMQNYVSMGLITLVWAVWGYSLCFGTSKNGVIGSARTHYFLENLATQELPYAEGMPGLVFAGFQGMFAVIAPSLMTGAFADRVRFVPYVLFIFFWVHLVYFPFAHWVWGGGWMARNGVKDFAGGIVVHITAGFSALATVVALPNRRKLEGDDVDTNPHNIPFVALGTGLLWFGWFGFNGGSALAANESAALAAMNSEISASAALFFWLMLEWKMEGKPTLVGACVGAIAGLATITPCAAYVKPWAALTIGTLCVPWCYACIELTKKYNLDDALDVWAVHGMGGFFGTLCVGIFSSAAMTGNAFEAGGKLFGKQLLAAVGCAAYSFVMGYAIIKVLEKFMDVVPREGDRRMGLDVSMHGAKAYSEDPSGSKKGGAVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4RX23</accession>
    <name>A4RX23_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_5133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417922.1">
        <property type="nucleotide sequence ID" value="XM_001417885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RX23"/>
    <dbReference type="STRING" id="436017.A4RX23"/>
    <dbReference type="GeneID" id="5001970"/>
    <dbReference type="Gramene" id="ABO96215">
        <property type="protein sequence ID" value="ABO96215"/>
        <property type="gene ID" value="OSTLU_5133"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5133"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_18_0_1"/>
    <dbReference type="OMA" id="ARCSATN"/>
    <dbReference type="OrthoDB" id="497922at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039323">
        <property type="entry name" value="ANKRD_45/46/60"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677:SF4">
        <property type="entry name" value="USHER SYNDROME TYPE-1G PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="19004" checksum="82EC97A5C7D4AC49" modified="2007-05-15" version="1" fragment="single">ALHAAVASGDVVDARELLELGANVNEPKSEEDSTTPLLVAAAKGNVEMVKLLIKSGANLDAQDDCDNNALHVACSKGHVNVVSRLIKAGCDVETRAGNGATALHLAARKGHDDVVELLLDSDMQIESLDGKGATPLHAACSGGYEDVVGLLLKRGANTAAVDAKGKTPRQIANKKGHDDCAKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXG6</accession>
    <name>A4RXG6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417746.1">
        <property type="nucleotide sequence ID" value="XM_001417709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXG6"/>
    <dbReference type="GeneID" id="5001747"/>
    <dbReference type="Gramene" id="ABO96039">
        <property type="protein sequence ID" value="ABO96039"/>
        <property type="gene ID" value="OSTLU_15411"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15411"/>
    <dbReference type="HOGENOM" id="CLU_327446_0_0_1"/>
    <dbReference type="OMA" id="HMNERER"/>
    <dbReference type="OrthoDB" id="10565886at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="847"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="819"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="855"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="879" mass="98250" checksum="1E2F641571720CCE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXH9</accession>
    <name>A4RXH9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RWP-RK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_31702</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative transcription factor.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417754.1">
        <property type="nucleotide sequence ID" value="XM_001417717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXH9"/>
    <dbReference type="STRING" id="436017.A4RXH9"/>
    <dbReference type="GeneID" id="5001846"/>
    <dbReference type="Gramene" id="ABO96047">
        <property type="protein sequence ID" value="ABO96047"/>
        <property type="gene ID" value="OSTLU_31702"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31702"/>
    <dbReference type="HOGENOM" id="CLU_768131_0_0_1"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044607">
        <property type="entry name" value="RKD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373">
        <property type="entry name" value="PROTEIN RKD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373:SF2">
        <property type="entry name" value="RWP-RK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="8">
        <location>
            <begin position="33"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="361" mass="39786" checksum="68DAA1F16C2E26FD" modified="2007-05-15" version="1">MSAVETTTNTGLPIRMPNDARGATHAIDPLSDVHTAVKSATGTKIIALIDVSSRFALPIAQAAKELDVCVTVLKSTCRAFGIMRWPYRKMRKLNTMIKQLERSARNAAEENILHHRMKRLEACRRARDLLVLEAEANARARIGKPASQQSAKAEIASTGARYDSSGRLGNFKDPGYAFDTDHKGYALHEAMRKMMETEGLDTIGRSGHVDVESDPLSELASQVTAVQERFVRRPNRNKRQLPTRCPEEMALHEFVMGNPGLEAMASLTARLRRQKESKKQTSEHADDADGEVDIDGDDGKQIAWIVSSQSPAYTVNVRPSNPTARIPDVLVEERSRREATSPLEPSLALFPLNVSAIHSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXP0</accession>
    <name>A4RXP0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Caltractin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Centrin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_31762</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">This calcium-binding protein is found in the basal body complexes (the functional homolog of the centrosome in animal cell). In mitotic cells it is specifically associated with the poles of the mitotic spindles at the sites of the duplicated basal body complexes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the centrin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418026.1">
        <property type="nucleotide sequence ID" value="XM_001417989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXP0"/>
    <dbReference type="STRING" id="436017.A4RXP0"/>
    <dbReference type="GeneID" id="5002104"/>
    <dbReference type="Gramene" id="ABO96319">
        <property type="protein sequence ID" value="ABO96319"/>
        <property type="gene ID" value="OSTLU_31762"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31762"/>
    <dbReference type="eggNOG" id="KOG0028">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_18_2_1"/>
    <dbReference type="OMA" id="CIEAREF"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000077">
        <property type="entry name" value="Centrin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000070">
        <property type="entry name" value="Centrin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF59">
        <property type="entry name" value="EF-HAND SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="19"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="92"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="128"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO96319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="163" mass="18596" checksum="CA83FD6CF26A23C9" modified="2007-05-15" version="1">MWAGPARKGKGRSSGLSEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPNKDEIKKMIADIDKDGNGTIDFEEFLAMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMTDEELQEMIDEADRDGDGEVNEEEFFRIMKKTSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXU9</accession>
    <name>A4RXU9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_31824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417817.1">
        <property type="nucleotide sequence ID" value="XM_001417780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXU9"/>
    <dbReference type="GeneID" id="5001768"/>
    <dbReference type="Gramene" id="ABO96110">
        <property type="protein sequence ID" value="ABO96110"/>
        <property type="gene ID" value="OSTLU_31824"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31824"/>
    <dbReference type="HOGENOM" id="CLU_1443272_0_0_1"/>
    <dbReference type="OrthoDB" id="448399at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20905" checksum="2EBF1345D6B06D43" modified="2007-05-15" version="1">MGKKKRKRKDKDGQAAGAEAKKKLFTKKDWTCACGFLNYSKNKLACHKCKAARPARVGRNAAEDYLSRWAVMETTEVNAIHHQFLLKQVGIDNELRDEFFDFFVEYCGSLPDSRRRKIVSGAKKVRARLDAILQACDNRKGAASESDEGEDEDKAPVTANVAQTKKRGNRGKKGRGKQAAKASPTPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXV5</accession>
    <name>A4RXV5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_31831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418062.1">
        <property type="nucleotide sequence ID" value="XM_001418025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXV5"/>
    <dbReference type="STRING" id="436017.A4RXV5"/>
    <dbReference type="GeneID" id="5002146"/>
    <dbReference type="Gramene" id="ABO96355">
        <property type="protein sequence ID" value="ABO96355"/>
        <property type="gene ID" value="OSTLU_31831"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_31831"/>
    <dbReference type="HOGENOM" id="CLU_790828_0_0_1"/>
    <dbReference type="OMA" id="AANECMA"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46268">
        <property type="entry name" value="STRESS RESPONSE PROTEIN NHAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46268:SF6">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN UP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="3">
        <location>
            <begin position="215"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="351" mass="40107" checksum="E5322BAEFC183D62" modified="2007-05-15" version="1">MLDDRLTVHQLPQMAGFDESRLTVVVAFDFGYQIHDKACWRWLEKWLLLDPSSINLTLLHIETVRDPAKLELTSYRYISLEDSSRFLPYDVWRSLRRNKYPHHEVVLLQTNIGISKSILDYMRYDAPRHAMLVLGSRHHTPSIIPRFLMGSVSSDVTAKIDSHPVLLIRTRLFKDVSDLREDTVGSAYLGLREEGKEFGCGRSICIAVDGAHVKSLVHYVMREIMRKTDIVQIVHCAADENASTLARVSAELEEIREELKTFLDDENQLDSVLLDFTGDIREKVLEHVDERMSSKAIDLLVIGNRTRRAVLSRNIIGSTAQYILQYAHVPVLMVPDALIEYMEDDAMSTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RXX9</accession>
    <name>A4RXX9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_94394</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001417831.1">
        <property type="nucleotide sequence ID" value="XM_001417794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RXX9"/>
    <dbReference type="STRING" id="436017.A4RXX9"/>
    <dbReference type="GeneID" id="5001724"/>
    <dbReference type="Gramene" id="ABO96124">
        <property type="protein sequence ID" value="ABO96124"/>
        <property type="gene ID" value="OSTLU_94394"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94394"/>
    <dbReference type="eggNOG" id="KOG1527">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_7_0_1"/>
    <dbReference type="OMA" id="VIYMGIL"/>
    <dbReference type="OrthoDB" id="508204at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000001">
        <property type="entry name" value="Siroheme synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004790">
        <property type="entry name" value="PRK06136.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF3">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="6">
        <location>
            <begin position="4"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABO96124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="237" mass="24597" checksum="53F103266B6EF736" modified="2007-05-15" version="1">MGSVCLVGAGPGGVDALTMGAARALANADVVVYDDLGGSSEDVLALATKANAEFVSVGKRGGSAKSWTQSDICELLVELARSGKRVARLKGGCPSVFARVSDEIAALRKHGVHTTMIPGISSALSAPLSVGIPLTDRELGRHFSVTSAHDPNSIDFAAFAGIDTCVFLMVGRTLPIVVESLTREGNKSPTTPCCVIRNGMQPDERSWFGSLRDIVEKTSGESLSPCILVVGNVVTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RY60</accession>
    <name>A4RY60_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HotDog ACOT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_38503</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000585">
        <property type="protein sequence ID" value="ABO96406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418113.1">
        <property type="nucleotide sequence ID" value="XM_001418076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RY60"/>
    <dbReference type="STRING" id="436017.A4RY60"/>
    <dbReference type="GeneID" id="5001886"/>
    <dbReference type="Gramene" id="ABO96406">
        <property type="protein sequence ID" value="ABO96406"/>
        <property type="gene ID" value="OSTLU_38503"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_38503"/>
    <dbReference type="eggNOG" id="KOG2763">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032862_4_0_1"/>
    <dbReference type="OMA" id="ETWERTY"/>
    <dbReference type="OrthoDB" id="331699at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03442">
        <property type="entry name" value="BFIT_BACH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655:SF0">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="HotDog ACOT-type" evidence="5">
        <location>
            <begin position="195"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="368" mass="41354" checksum="56E8FF08B9961B85" modified="2007-05-15" version="1">MYKSHGSGAVRMGRILEDLDSLAGNIAFFHADDDDDTTKTPQLVTASVDRVRLNRPLSLDKDVVLRGEVAFVGTSSMVIRMEADDDGAVEDATVDDDRTEPALAADFTFVARDPETNKSWPVNPLVCVSRRHKERAQEIQASILRKRLRSKKGDAVLNETLIKHRTEWVRSIRERACLNQEMPALTAGYNEVMTTQTMAENMFVAQPQQRNLSGRVFGGFLLRRAYELAFANCQLFSGGHPMFVEMSDIDFTLPVNIGDLVRFKCKVLHTVNAEEARCGKPSVYLEVRAIVTNPHKVTSAVANKFFFKFNVAEFAEADGTTTGEPVRLRRVLPESNDEALLIWDKCIRRTLCDDNDFDVRNNLSMMTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYG8</accession>
    <name>A4RYG8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_92856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418164.1">
        <property type="nucleotide sequence ID" value="XM_001418127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYG8"/>
    <dbReference type="GeneID" id="5002267"/>
    <dbReference type="Gramene" id="ABO96457">
        <property type="protein sequence ID" value="ABO96457"/>
        <property type="gene ID" value="OSTLU_92856"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_92856"/>
    <dbReference type="HOGENOM" id="CLU_1181853_0_0_1"/>
    <dbReference type="OMA" id="FIRDCAA"/>
    <dbReference type="OrthoDB" id="497528at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="235" mass="26137" checksum="901D6FE3B12820AF" modified="2007-05-15" version="1">MPRATTRATTRATTRATTRAATTATRRSRTTRAARATTRRRATSIEDVPPEDVAIVVELLDSESGEEVTEKVDAMAKGGLLTAGVVEAARVIVEANRQSGQDPDVVALLEDVYKTLDVRLREMAATQVKDALTFAQELMKYFTAEDLERDESVAVTKVQLMMREEFERPGGVSREALAKYLDEVLPVMDQQDERIQSGLETATTPEQQAQIVQLMMQRTKERMQIEFIRDCAAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYI2</accession>
    <name>A4RYI2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_40972</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418395.1">
        <property type="nucleotide sequence ID" value="XM_001418358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYI2"/>
    <dbReference type="STRING" id="436017.A4RYI2"/>
    <dbReference type="GeneID" id="5002351"/>
    <dbReference type="Gramene" id="ABO96688">
        <property type="protein sequence ID" value="ABO96688"/>
        <property type="gene ID" value="OSTLU_40972"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40972"/>
    <dbReference type="eggNOG" id="KOG2311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007831_2_2_1"/>
    <dbReference type="OMA" id="CNPAMGG"/>
    <dbReference type="OrthoDB" id="3329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070899">
        <property type="term" value="P:mitochondrial tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1800:FF:000001">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.570:FF:000001">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000094">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000119">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="entry name" value="GidA associated domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1800">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG/GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049312">
        <property type="entry name" value="GIDA_C_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047001">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00136">
        <property type="entry name" value="mnmG_gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="GLUCOSE INHIBITED DIVISION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21680">
        <property type="entry name" value="GIDA_C_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="SAM_GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01228">
        <property type="entry name" value="GIDA_assoc_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain" evidence="8">
        <location>
            <begin position="605"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO96688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="693" mass="76176" checksum="C890880C46E4F3C7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYJ0</accession>
    <name>A4RYJ0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">OSTLU_10320</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LpxC family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418401.1">
        <property type="nucleotide sequence ID" value="XM_001418364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYJ0"/>
    <dbReference type="STRING" id="436017.A4RYJ0"/>
    <dbReference type="GeneID" id="5002357"/>
    <dbReference type="Gramene" id="ABO96694">
        <property type="protein sequence ID" value="ABO96694"/>
        <property type="gene ID" value="OSTLU_10320"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10320"/>
    <dbReference type="eggNOG" id="ENOG502QT9Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046528_0_0_1"/>
    <dbReference type="OMA" id="IVFYRSD"/>
    <dbReference type="OrthoDB" id="10265200at2759"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001289">
        <property type="term" value="P:lipid X metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="entry name" value="lpxc deacetylase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="entry name" value="lpxc deacetylase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694:SF1">
        <property type="entry name" value="UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABO96694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="271" mass="29750" checksum="2471EA442E89B43A" modified="2007-05-15" version="1" fragment="single">QQTIRRSVTYAGTGLRSGEVELMRVRPAKAGEGRYFVKVPSVRASYELANEDVRLSSELNGDFVVRGAEHLLSALEAMGIDNCRIELEGTGEVPIMDGSASSYAYDICCVGLTPARAVDGGEVPRMAWKITENVMVQEGDAFMMFNVDDVSKLTYGIDLSYKTTAIGKQWESWTPTEDAPYVFHVSPARMFGTMNDFTAYYRAGYIRAGLEDCALIANGDQYWNAPLRVNNEPARHKILDLIGDLSLLAEPGMSGVPVGHVIAYKAGHKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYK7</accession>
    <name>A4RYK7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_32062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418408.1">
        <property type="nucleotide sequence ID" value="XM_001418371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYK7"/>
    <dbReference type="GeneID" id="5002570"/>
    <dbReference type="Gramene" id="ABO96701">
        <property type="protein sequence ID" value="ABO96701"/>
        <property type="gene ID" value="OSTLU_32062"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32062"/>
    <dbReference type="HOGENOM" id="CLU_486979_0_0_1"/>
    <dbReference type="OrthoDB" id="10683226at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO96701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="560" mass="64528" checksum="5891398E8ABE63F5" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4RYX7</accession>
    <name>A4RYX7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CFA20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418239.1">
        <property type="nucleotide sequence ID" value="XM_001418202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RYX7"/>
    <dbReference type="STRING" id="436017.A4RYX7"/>
    <dbReference type="GeneID" id="5002338"/>
    <dbReference type="Gramene" id="ABO96532">
        <property type="protein sequence ID" value="ABO96532"/>
        <property type="gene ID" value="OSTLU_15789"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15789"/>
    <dbReference type="eggNOG" id="KOG3213">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_746777_0_0_1"/>
    <dbReference type="OrthoDB" id="10261083at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="2">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="371" mass="41601" checksum="19FEA930600A32E6" modified="2007-05-15" version="1">MGATQPILAMQLRASGGANFSFEVRVRDAADARRRLVFSSSFSEVRPTPLHCQVPLRDLPRDEWVTLLLPLVELVPVCFSSGSAGYRSIDAIVIRGECSIRKIFTLRGDTQAQAWTESRAGETPRQAIVIPRECDFPPGVRAAAHTVIPSQDPALYDAHEEECRVRERNREVRMPIKVAFGRRAPTSQRERLRERADAAPARASDDHTDVRWSDLDQIMSNLRVRDAGGAGVRHSLASSSSSSSYASSRRTADEAAEELDMRNVNVSLGNLSIHGGREHHRYADVDDEDVDEGDEDVDEGDEDVDEDEDNDYEDNDYDEDDYEDDDYEDDDYENDASRLEDDDEILSPFDGDVDDDHDDRAFDLDDSDVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZB3</accession>
    <name>A4RZB3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TatD related DNase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_5749</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418545.1">
        <property type="nucleotide sequence ID" value="XM_001418508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZB3"/>
    <dbReference type="STRING" id="436017.A4RZB3"/>
    <dbReference type="GeneID" id="5002511"/>
    <dbReference type="Gramene" id="ABO96838">
        <property type="protein sequence ID" value="ABO96838"/>
        <property type="gene ID" value="OSTLU_5749"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5749"/>
    <dbReference type="eggNOG" id="KOG3020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_1_0_1"/>
    <dbReference type="OMA" id="YGGSQKH"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO96838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="30755" checksum="28C8D4425F39D7D7" modified="2007-05-15" version="1" fragment="single">VDVGANLTDGMFRGVYRGKRAHEDDLGAVLRRAREAGVSDIIVTAGTLEEAREAVALARETREDGAAPRLYATCGVHPTRCGAFADDVDGADAHLEKLKRVALDGKASGTIVAIGEMGLDYDRLEFCDAATQKEMFEKQFALAEATSLPLFLHMRAACDDFLEIIDRNAHRFTAGVVHSFTGGAREAAAVLARENLLIGLNGCSLKTQENLDVVKTIPLDRIVLETDAPWCGIKPTHAGFAAVAPPLSWPKPVKKEKWFAGALIKDRCEPAHIVCVAQIIACAHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZC7</accession>
    <name>A4RZC7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-synthesizing GTPase</fullName>
            <ecNumber evidence="3">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_32338</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418552.1">
        <property type="nucleotide sequence ID" value="XM_001418515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZC7"/>
    <dbReference type="STRING" id="436017.A4RZC7"/>
    <dbReference type="GeneID" id="5002518"/>
    <dbReference type="Gramene" id="ABO96845">
        <property type="protein sequence ID" value="ABO96845"/>
        <property type="gene ID" value="OSTLU_32338"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32338"/>
    <dbReference type="eggNOG" id="KOG0466">
        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="component" value="Chromosome 6"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:translation initiation factor activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:formation of translation preinitiation complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="eIF2_gamma"/>
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    </dbReference>
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        <property type="entry name" value="eIF2G"/>
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        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
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        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
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        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003077">
        <property type="entry name" value="PRK04000.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="34"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO96845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="463" mass="50157" checksum="166AA5C44A2FA960" modified="2007-05-15" version="1">MVYACGDDGLSVQDLATLDVGSLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLGYANAKIYKCEDEKCPRPDCYRAYSSTKEDAPACEVKGFEDKKMQLVRHVSFVDCPGHDILMATMLNGAAVMDGALLLIAGNETCPQPQTSEHLAAVEIMRLKHIIILQNKIDLVQENAAANQYDTICKFIQGTIADGAPVIPISAQLKYNIDVVCEYIIKKIPVPERNFISPPNMIVIRSFDVNKPGAEVEEIQGGVAGGSILQGVLKVGQDIEVRPGIVTKDADGKIQCKPIMTRIVSLFAEQNLLQYAVPGGLIGVGTTCDPTLTRADRLVGQVLGEVGKLPEVFTELEVNFFLLRRLLGVRTQGSERQGKVSKLAKSEVLMLNIGSMCTGARVVAVKSDLAKLQLTSPVCTKVGEKVALSRRVEKHWRLIGWGSIQAGTELSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZH8</accession>
    <name>A4RZH8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_15947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000586">
        <property type="protein sequence ID" value="ABO96630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418337.1">
        <property type="nucleotide sequence ID" value="XM_001418300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZH8"/>
    <dbReference type="STRING" id="436017.A4RZH8"/>
    <dbReference type="GeneID" id="5002195"/>
    <dbReference type="Gramene" id="ABO96630">
        <property type="protein sequence ID" value="ABO96630"/>
        <property type="gene ID" value="OSTLU_15947"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15947"/>
    <dbReference type="eggNOG" id="ENOG502QTEG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_848342_0_0_1"/>
    <dbReference type="OMA" id="YDKYFES"/>
    <dbReference type="OrthoDB" id="286233at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044243">
        <property type="entry name" value="FLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47310">
        <property type="entry name" value="PROTEIN FLUORESCENT IN BLUE LIGHT, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47310:SF2">
        <property type="entry name" value="PROTEIN FLUORESCENT IN BLUE LIGHT, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="241"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO96630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="328" mass="35073" checksum="5DF437E29CB43059" modified="2007-05-15" version="1">MMRTTTATTRTTTRVAALGARATGRGRGRGRDARARASGDAQRAGADGDARDDARRGGATTRKNRRGLLGAGFAAATAGLTGLTRAANAAPTLPKELTEPDEIFREDFNVQFAGLTVDHKDLIYALVVGQTIGFVGSAVGGAEARKRAEEIERLNSTLLKVNKEVRKELRSSQGRKVAFSTMDSSDEASSETVLEIISLLKSGKSKLKAQASQEAKETFTKARQLIDANQSALKEPWKAVRKAERGLGAASARLGEYDEALSHMKTVLKLSTEHDDTSVATDACGIIADIYAEMDQIEVAADWYDKYFESLAIEDAKEAAEAGSSSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZL8</accession>
    <name>A4RZL8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_15983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418595.1">
        <property type="nucleotide sequence ID" value="XM_001418558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZL8"/>
    <dbReference type="GeneID" id="5002914"/>
    <dbReference type="Gramene" id="ABO96888">
        <property type="protein sequence ID" value="ABO96888"/>
        <property type="gene ID" value="OSTLU_15983"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_15983"/>
    <dbReference type="eggNOG" id="ENOG502RV0I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_337537_0_0_1"/>
    <dbReference type="OMA" id="YLQRRPF"/>
    <dbReference type="OrthoDB" id="498847at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43939:SF68">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 290 KDA-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43939">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672047" evidence="3">
        <location>
            <begin position="23"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="826"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="844" mass="91839" checksum="44CDBFA307713BF1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>A4RZY9</accession>
    <name>A4RZY9_OSTLU</name>
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        <submittedName>
            <fullName evidence="4">Plastid ribosomal protein L27 large ribosomal subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PRPL27</name>
        <name evidence="4" type="ORF">OSTLU_32559</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO96945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001418615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RZY9"/>
    <dbReference type="STRING" id="436017.A4RZY9"/>
    <dbReference type="GeneID" id="5002815"/>
    <dbReference type="Gramene" id="ABO96945">
        <property type="protein sequence ID" value="ABO96945"/>
        <property type="gene ID" value="OSTLU_32559"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_32559"/>
    <dbReference type="eggNOG" id="KOG4600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095424_2_0_1"/>
    <dbReference type="OMA" id="RQCGSTW"/>
    <dbReference type="OrthoDB" id="496407at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="50S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_bL27"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_bL27_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO96945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="161" mass="17360" checksum="31DF9D7A8FBF2C4E" modified="2007-05-15" version="1">MHAALSSKLSTVALRIAPARVDARAPRRAVIECAHKKGTGSTKNGRDSNPQYLGVKKYGEEKVQVGSIIVRQRGNKFHAGAGVGTGKDFTLFALRDGEVMFKVGANKKKFVTVVDTVDRSGRADGQPTRKDKRKAMYSPRAVVRAALEEGISAPGVERVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4S0S2</accession>
    <name>A4S0S2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL18c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">CL18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRPL18</name>
        <name evidence="9" type="ORF">OSTLU_16290</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000587">
        <property type="protein sequence ID" value="ABO97082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001418789.1">
        <property type="nucleotide sequence ID" value="XM_001418752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S0S2"/>
    <dbReference type="STRING" id="436017.A4S0S2"/>
    <dbReference type="GeneID" id="5002850"/>
    <dbReference type="Gramene" id="ABO97082">
        <property type="protein sequence ID" value="ABO97082"/>
        <property type="gene ID" value="OSTLU_16290"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16290"/>
    <dbReference type="eggNOG" id="KOG1870">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098841_0_1_1"/>
    <dbReference type="OMA" id="NKQIYAQ"/>
    <dbReference type="OrthoDB" id="1932324at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000001">
        <property type="entry name" value="50S ribosomal protein L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_uL18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_uL18_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_uL18_bac/plant/anim"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00082729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO97082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="13401" checksum="6AED5221089F7E68" modified="2007-05-15" version="1">MTPKEAKRQQRHRKIRSKISGSSERPRISVYRSNQHVYVQVIDDENQKTIAALGTMSASVKAVIGSEEWKGKTVESAEQVGKMLGAVCVEKGITQAVFDRGGFLYHGRVKAIADGARAAGVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>A4S171</accession>
    <name>A4S171_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_50293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419313.1">
        <property type="nucleotide sequence ID" value="XM_001419276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S171"/>
    <dbReference type="STRING" id="436017.A4S171"/>
    <dbReference type="GeneID" id="5003402"/>
    <dbReference type="Gramene" id="ABO97606">
        <property type="protein sequence ID" value="ABO97606"/>
        <property type="gene ID" value="OSTLU_50293"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_50293"/>
    <dbReference type="eggNOG" id="KOG0718">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019611_2_0_1"/>
    <dbReference type="OMA" id="QLDKHTM"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055225">
        <property type="entry name" value="DNAJC11-like_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22774">
        <property type="entry name" value="DNAJC11_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="13"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO97606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="571" mass="62909" checksum="E6475ED54487B82C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S188</accession>
    <name>A4S188_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BSD2 cysteine rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_33012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419107.1">
        <property type="nucleotide sequence ID" value="XM_001419070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S188"/>
    <dbReference type="STRING" id="436017.A4S188"/>
    <dbReference type="GeneID" id="5003271"/>
    <dbReference type="Gramene" id="ABO97400">
        <property type="protein sequence ID" value="ABO97400"/>
        <property type="gene ID" value="OSTLU_33012"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33012"/>
    <dbReference type="eggNOG" id="ENOG502S25V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2019090_0_0_1"/>
    <dbReference type="OrthoDB" id="2019540at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1580.10">
        <property type="entry name" value="ABC transporter ATPase like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057453">
        <property type="entry name" value="BSD2_CRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25436">
        <property type="entry name" value="BSD2_CRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD2 cysteine rich" evidence="2">
        <location>
            <begin position="65"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO97400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="123" mass="12690" checksum="7D88BCC4C8358EBB" modified="2007-05-15" version="1">MRVGVPSTRAPSTRPSPSFAPSASSSSARASRPARANTVSTLFATGDDARGDASRRADPAPETRCPVCRGTGWKPCGQCEGTGINPSDAFGGKFKAGDACWLCEGKNGARTMCGNCVDLTDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4S199</accession>
    <name>A4S199_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">GTP cyclohydrolase II domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">OSTLU_87976</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 2 phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419113.1">
        <property type="nucleotide sequence ID" value="XM_001419076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S199"/>
    <dbReference type="STRING" id="436017.A4S199"/>
    <dbReference type="GeneID" id="5003417"/>
    <dbReference type="Gramene" id="ABO97406">
        <property type="protein sequence ID" value="ABO97406"/>
        <property type="gene ID" value="OSTLU_87976"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_87976"/>
    <dbReference type="eggNOG" id="KOG1284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020273_1_2_1"/>
    <dbReference type="OMA" id="GGVHMAM"/>
    <dbReference type="OrthoDB" id="60371at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10990:FF:000001">
        <property type="entry name" value="Riboflavin biosynthesis protein RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000001">
        <property type="entry name" value="Riboflavin biosynthesis protein RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00179">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01283">
        <property type="entry name" value="RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016299">
        <property type="entry name" value="Riboflavin_synth_RibBA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001591">
        <property type="entry name" value="PRK00393.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006803">
        <property type="entry name" value="PRK09311.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00505">
        <property type="entry name" value="ribA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF18">
        <property type="entry name" value="3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001259">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="20">
        <location>
            <begin position="272"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ABO97406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="487" mass="53039" checksum="A3850E7CFF35D8A2" modified="2007-05-15" version="1">MSRCASARAPARDARRRDARAWTRRARTLATTTRRRDGARATRHRATTRARATTGDDPDAPTAGFAAVADALEDVAKGKFVVVLDDEDRENEGDLIGAADKMTAESLAFMIRHTSGLVCVSLEDSRADALDLPLMVDSQSNKDAMKTAFTVSVDLATSTTGISASERAMTINALGSDETTAAAFVRPGHVFPLRYRAGGVLKRAGHTEAAVDLARMAGSSPVGVLCEIVNDEDGSMARLPQLKVFAEKHGLKMVLISDMIRYRRAREKMVERTAVARLPTEYGNFTCVSYKNTLDGHEHVAFLYGEHEGDVSGAVGEDMLVRVHSECLTGDIFKSARCDCGNQLDMAMRRIAGEGKGCIVYLRGQEGRGIGLGHKLRAYNLQDEGRDTVQANEDLGFPADTREYGVGAQILQDLGVTSLRLMTNNPAKYNGLSGYGLKVTGRVPLFAPVTMENKRYIDTKRMKMGHLFEMLEGVEPSQAESEQKPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1F8</accession>
    <name>A4S1F8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_33084</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419141.1">
        <property type="nucleotide sequence ID" value="XM_001419104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1F8"/>
    <dbReference type="GeneID" id="5003464"/>
    <dbReference type="Gramene" id="ABO97434">
        <property type="protein sequence ID" value="ABO97434"/>
        <property type="gene ID" value="OSTLU_33084"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33084"/>
    <dbReference type="HOGENOM" id="CLU_822190_0_0_1"/>
    <dbReference type="OMA" id="GWLCTCE"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="53"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO97434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="304" mass="34652" checksum="AB3A50BFA68BC981" modified="2007-05-15" version="1">MSNHPSVAWSAARVALGVLFWEGQFQISKQCFAKRLPETSEKERTYKRAVSSYIVSFVHAFFLTWAGWRIVFKLRLGSVAERLSLYANADASFVGFVEVVTIAFFSYVVYDLLHVIEQYPDLGGVDILAHHLGFFTASLLAYAYGAYPFMLGWLCTCETSTPILNTRFFIKSWREMEYTLPNIDALAKFFGMKTRGVVAGNWLEYYVSVAFLWVFVAVRVVGYGGALIALTFDLKSVEDNYIPYPVRATLYALTCCGFVLNAVWTYKIYGMVKHFRRKTLKQRDACEEPISDSEEEDPSVQKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S1X2</accession>
    <name>A4S1X2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_16577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000588">
        <property type="protein sequence ID" value="ABO97733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419440.1">
        <property type="nucleotide sequence ID" value="XM_001419403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S1X2"/>
    <dbReference type="GeneID" id="5003485"/>
    <dbReference type="Gramene" id="ABO97733">
        <property type="protein sequence ID" value="ABO97733"/>
        <property type="gene ID" value="OSTLU_16577"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16577"/>
    <dbReference type="HOGENOM" id="CLU_1135107_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO97733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="245" mass="27598" checksum="2C6153D4F0D15BAB" modified="2007-05-15" version="1">MDEDEGADARGKREMDAMDAMAETADAETARTIPPLPGEDAALVAEYYAQFQVRMELDRARLARRAAVREDEAVSANDDDDDDDDESEDSSSQTEFGEESDAEDDDAEDDDAVEVISKSDVDIRDNAFDRLRLKAIEAYRELEKRIYRVAREGAEAIAPLSRDLWDRFVRCTRRMARRKFDLQKEASSLTDVIVVVTASGIAFIVARKCFSALMARNDRAERAARSVEIDLARCWHDAGTYGYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S225</accession>
    <name>A4S225_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HhH-GPD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_33300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419671.1">
        <property type="nucleotide sequence ID" value="XM_001419634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S225"/>
    <dbReference type="STRING" id="436017.A4S225"/>
    <dbReference type="GeneID" id="5003702"/>
    <dbReference type="Gramene" id="ABO97964">
        <property type="protein sequence ID" value="ABO97964"/>
        <property type="gene ID" value="OSTLU_33300"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33300"/>
    <dbReference type="eggNOG" id="KOG4161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051101_0_0_1"/>
    <dbReference type="OMA" id="YYAHDAW"/>
    <dbReference type="OrthoDB" id="10265068at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="37443" checksum="7608E8A9B87C5AA9" modified="2007-05-15" version="1">MPDENLTEYERQRLAHVQRNREYMARLGVNALADDIRNKMSSRKISTTSRKRVKREEPSEPTRRSSRVVGVKAEYDGSTIDALLDEDEENENGRARKRASVDAELDDDELAKDVVATSREWLAEAREKLLATRADVANSFVEKSAKDEAWRRDAVARWGDSVPSARSVSDWKAWTMSRLGTPPPPSPMQLLQEYYAHDAWQLLIACALMSRVASGALKHECISNFFAKFPTPSAALAADSQDVFEIIKRLGLFPGRMRTIVEVSTKFLLETGEFEVGLEPELKIYGIGEFGVDSFEIFARGDVRRKPKDCNLQSFCAWQRRHGNGKVKVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A4S261</accession>
    <name>A4S261_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_33338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419693.1">
        <property type="nucleotide sequence ID" value="XM_001419656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S261"/>
    <dbReference type="GeneID" id="5003630"/>
    <dbReference type="Gramene" id="ABO97986">
        <property type="protein sequence ID" value="ABO97986"/>
        <property type="gene ID" value="OSTLU_33338"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_33338"/>
    <dbReference type="HOGENOM" id="CLU_2744572_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO97986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="71" mass="8062" checksum="83F8F2AD294F99BB" modified="2007-05-15" version="1">MRCIGVALCRAPSRARCGDAKTDARLGLLHLIRADTVLAYQRIRLFVWANSMKTVVFDTYREIPNTGFKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S283</accession>
    <name>A4S283_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_34929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO97780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419487.1">
        <property type="nucleotide sequence ID" value="XM_001419450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S283"/>
    <dbReference type="STRING" id="436017.A4S283"/>
    <dbReference type="GeneID" id="5003643"/>
    <dbReference type="Gramene" id="ABO97780">
        <property type="protein sequence ID" value="ABO97780"/>
        <property type="gene ID" value="OSTLU_34929"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34929"/>
    <dbReference type="eggNOG" id="KOG1659">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045277_9_0_1"/>
    <dbReference type="OMA" id="MFMVELM"/>
    <dbReference type="OrthoDB" id="653904at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001046">
        <property type="term" value="F:core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22906">
        <property type="entry name" value="HFD_DRAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF5">
        <property type="entry name" value="DR1-ASSOCIATED COREPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="3">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO97780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="98" mass="10413" checksum="FD8CAA4A7642CBF8" modified="2007-05-15" version="1" fragment="single">MPPKGKTNLLAARIKRVMQKDEDVGKIAGPAPIVMGKALELFVKQLVTTANDVAVLHGSKTVNGSHLKGAVAMVPEAFDFLSDIVEKAKDLGPPPDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2A5</accession>
    <name>A4S2A5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G10 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_10590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419717.1">
        <property type="nucleotide sequence ID" value="XM_001419680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2A5"/>
    <dbReference type="STRING" id="436017.A4S2A5"/>
    <dbReference type="GeneID" id="5003589"/>
    <dbReference type="Gramene" id="ABO98010">
        <property type="protein sequence ID" value="ABO98010"/>
        <property type="gene ID" value="OSTLU_10590"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_10590"/>
    <dbReference type="eggNOG" id="KOG3404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087132_1_1_1"/>
    <dbReference type="OMA" id="QWEVFQI"/>
    <dbReference type="OrthoDB" id="277109at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16874" checksum="1110362ECEBDE457" modified="2007-05-15" version="1" fragment="single">RRLKGKQPPEGFDMIEHAIEDFENQMKDAVNEEHEGKRKNELSWRIHRIHWEKNRFVFDLMYKRKALKRELYDYLCREKIADQALISKWRKPGYENLCSLLSIQKSATNFGTASICRVPMASRAPQQRLTPNVKTGCISCCSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4S2V3</accession>
    <name>A4S2V3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_34718</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419811.1">
        <property type="nucleotide sequence ID" value="XM_001419774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S2V3"/>
    <dbReference type="STRING" id="436017.A4S2V3"/>
    <dbReference type="GeneID" id="5003762"/>
    <dbReference type="Gramene" id="ABO98104">
        <property type="protein sequence ID" value="ABO98104"/>
        <property type="gene ID" value="OSTLU_34718"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34718"/>
    <dbReference type="eggNOG" id="KOG0804">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009969_1_0_1"/>
    <dbReference type="OMA" id="WADASCP"/>
    <dbReference type="OrthoDB" id="273556at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16457">
        <property type="entry name" value="RING-H2_BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011422">
        <property type="entry name" value="BRAP2/ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047243">
        <property type="entry name" value="RING-H2_BRAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07576">
        <property type="entry name" value="BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="157"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="191"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="443"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="333"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="51814" checksum="B207200150F64838" modified="2007-05-15" version="1">MAHAARVERDDDDDDDDDDARRADGAPTVGATRGRVRLFKTTRDDGCATTTRRNANAACVVGVPSAIAIADFCRFVAGAMATTRSVRAVAGRGDGARSTYDAVLEFDDGDAADAFVENYHGRRYAMGREETCVAVRVVRVEEGAEASGTLGTEVPTCPVCLDRLDAEASGIVTTICEHAFHAECLSGWADASCPVCRYAHEPESKARCATCGKDHDLWVCLICGEVRCGRYAGACAVNHWTETNHTYALELGTQRVWDYVSDGFVHRLIQSKSGLEALVASKLDAIASEYDLLLTSQLESQRKYFEGLLQTANARCAGTISREDEDSRNAAVVARAMSEAKDAKRELKMLQKANASHVASIEQLRDELEHAHALSDTLAENVETLRAEATRAEKRKTIELAIKDARIKELEEENRDLMLFLDTSNKLSVDASLAEEIAGGTVVGIDTDTTPEPTPSRNRTHERLKGKVEAERRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>A4S317</accession>
    <name>A4S317_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_34638</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Small heat shock protein required for the establishment of auxin gradients and for patterning of the apical domain of the embryo. Involved in the specification of the cotyledon primordia. Also required for normal inflorescence and floral meristem function, normal developmental patterning and thermotolerance. Acts as a molecular chaperone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000589">
        <property type="protein sequence ID" value="ABO98132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419839.1">
        <property type="nucleotide sequence ID" value="XM_001419802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S317"/>
    <dbReference type="STRING" id="436017.A4S317"/>
    <dbReference type="GeneID" id="5003507"/>
    <dbReference type="Gramene" id="ABO98132">
        <property type="protein sequence ID" value="ABO98132"/>
        <property type="gene ID" value="OSTLU_34638"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_34638"/>
    <dbReference type="eggNOG" id="KOG2265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047332_2_0_1"/>
    <dbReference type="OMA" id="RQKEMGG"/>
    <dbReference type="OrthoDB" id="416217at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000001">
        <property type="entry name" value="Nuclear migration protein nudC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="8"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00053226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO98132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="20746" checksum="286A81F2D3A15D3C" modified="2007-05-15" version="1">MPNKGNGGEAEKYVWTQTLDDLEVRVAVPPGTKSKEIECAFAKNRFSFKLKTASGEPRIEGEFYAAITPDECYWTLEDNAYVSCFLQKAKTGAEWWPHVLVDDPKIDTKKVEPENSRLDDLDGETRSTVEKMMYDQRQKAMGLPTADEQTKQDALKKFMAAHPEMDFSNCKFDGVSGASPFDASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>A4S397</accession>
    <name>A4S397_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_16948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419880.1">
        <property type="nucleotide sequence ID" value="XM_001419843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S397"/>
    <dbReference type="GeneID" id="5004229"/>
    <dbReference type="Gramene" id="ABO98173">
        <property type="protein sequence ID" value="ABO98173"/>
        <property type="gene ID" value="OSTLU_16948"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_16948"/>
    <dbReference type="HOGENOM" id="CLU_388014_0_0_1"/>
    <dbReference type="OMA" id="PAMHELM"/>
    <dbReference type="OrthoDB" id="7700931at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672125" description="FAS1 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="223"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="401"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="591"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="712" mass="78344" checksum="AE35C25A8A0DAD92" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3D5</accession>
    <name>A4S3D5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">OSTLU_26018</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 15">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane. Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes. Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA. SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER. Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="12 15">Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="15">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419900.1">
        <property type="nucleotide sequence ID" value="XM_001419863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3D5"/>
    <dbReference type="STRING" id="436017.A4S3D5"/>
    <dbReference type="GeneID" id="5004136"/>
    <dbReference type="Gramene" id="ABO98193">
        <property type="protein sequence ID" value="ABO98193"/>
        <property type="gene ID" value="OSTLU_26018"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26018"/>
    <dbReference type="eggNOG" id="KOG0780">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_6_1_1"/>
    <dbReference type="OMA" id="MTIFVMD"/>
    <dbReference type="OrthoDB" id="10250817at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 15" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="16">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABO98193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="513" mass="55413" checksum="057577423402E9FD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3J1</accession>
    <name>A4S3J1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfotransferase</fullName>
            <ecNumber evidence="1">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_17021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3J1"/>
    <dbReference type="GeneID" id="5004058"/>
    <dbReference type="Gramene" id="ABO98221">
        <property type="protein sequence ID" value="ABO98221"/>
        <property type="gene ID" value="OSTLU_17021"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17021"/>
    <dbReference type="eggNOG" id="ENOG502T0Y4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_680410_0_0_1"/>
    <dbReference type="OMA" id="ISETLMH"/>
    <dbReference type="OrthoDB" id="498565at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="134"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO98221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="405" mass="45960" checksum="F158318AD335D7B1" modified="2007-05-15" version="1">MTVKQRPRTGGRATAREDGAREANEEARARASGRAARSATIGSGLALALWWASSPRWWTATRDEGKPAVDARAAAYAFGTSTEAISGWSLRDVAEFLAMSDARWLGSTVEATEAVSRDDGRKRVARRADGFARFVATHHKTGTALMHDVFSTIANRSSPPYTFFDVRAFEDAELVVNEVTGKGLERAARRRFREADIVLDYHFGKSLPAFIEQNETTRLLQSMISVSNAREYRIVHVVRDPLDVLVSGLAYHARSPNDERWLSRARVAELSYAEFLKTASPKDAIAAEMSFSDDEIRMLALTYVQCERNRDTCLNLRLEAFERNFDRTLERALRFLRFPSQNITSMIQIASVHDVSKWSEDELRKNEHYTKRIDRRPYYEAAREDDDIWRTITALRRAMGYDATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3K0</accession>
    <name>A4S3K0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-processing factor 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">OSTLU_17027</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001419932.1">
        <property type="nucleotide sequence ID" value="XM_001419895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S3K0"/>
    <dbReference type="STRING" id="436017.A4S3K0"/>
    <dbReference type="GeneID" id="5004264"/>
    <dbReference type="Gramene" id="ABO98225">
        <property type="protein sequence ID" value="ABO98225"/>
        <property type="gene ID" value="OSTLU_17027"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17027"/>
    <dbReference type="eggNOG" id="KOG0282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022571_2_1_1"/>
    <dbReference type="OMA" id="TLWHPHE"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000034">
        <property type="entry name" value="Pre-mRNA-processing factor 17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="207"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="251"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="335"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="467"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO98225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="500" mass="55244" checksum="E4889A2C16015EF0" modified="2007-05-15" version="1">MRVNLTYDEMTAPIEGPRHETREDRLTGRGARNHALGQVDATTVNAFSFDEQYNTYNSRGYAAAPSGTGVVGDADAMRASKGETAFNISAAKKRRIREEVLAGVATPASGETDTSAWAPARAAQKEKEYVKWHMDNREAKLRAKGKLEGLETGPGEDGGAQDDSKFTKFHGSEEVNYAGDSWIAAPKSEKRDGDGTCFAPNKCVHTFNGHTKGVSKIEFFPHTGHLLLSAGMDNVVKIWDVYNSRKCMRTYMGHDKAVKDVCFNGDGTRFVSTSWDKKVRLWDTETGKIIQTVTSGKIGYCAKIHPKQDNLVLIGQSDKKIVQWDMNNGDLVQEYDQHLGPVNSITFADGGERFMSSSDDKTLRVWEFGIPVTTKYIADPSMHSVPATAISNNGKYIIGQSLDNQIITFSVDERFRRNNKKRFGGHHNAGYACQPAFSTDDSTVVSGDGSGKIFFWDWKTSKIIKSVKAHAEVCIGVAWHPLKSSVVASCSWDKTIKLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3U9</accession>
    <name>A4S3U9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_2933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
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            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">CCE9901</strain>
        </source>
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        <property type="gene ID" value="OSTLU_2933"/>
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    <dbReference type="eggNOG" id="ENOG502QUXN">
        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="entry name" value="YvcK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CofD-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CofD"/>
    </dbReference>
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        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240:SF0">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="40240" checksum="23D722ED7144CA97" modified="2007-05-15" version="1" fragment="single">PKVVVFSGGTAMNVIAVELSELTQKVTHVIPVSDNGGSTSEIVRVLGGPAVGDLRSRCLRVTDESTPEAVAVKALLGHRLHPTDSALARDEWYKIQEGDHELWEGIGQDYANIIRRFLVHFHQEVTSKPIKERFDFVNGSIGNFFFAGARLFFRSMDAAIFLYSRVSRIPDDTHIVPCLLHKENERVNLAAELMNGTILRGQNEISHPSIDSKNVWDVDKVVTAYDPLESPIKRVFYASSLDPADDNFEVQPKPNPTVLENITDCDAILYGMGSLYTSIIPNVGLKGMAQCIASSTSKKLLMLNGSLDRETGTMTASEIVRAVVDAVNMRYTAAETNFDVKELITDVVYPKNGGITVDVDALAAMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S3X9</accession>
    <name>A4S3X9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_26209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF1 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="OSTLU_26209"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26209"/>
    <dbReference type="eggNOG" id="KOG2318">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OMA" id="YEMEMSW"/>
    <dbReference type="OrthoDB" id="498902at2759"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039754">
        <property type="entry name" value="Esf1"/>
    </dbReference>
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        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056750">
        <property type="entry name" value="RRM_ESF1"/>
    </dbReference>
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        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="RRM_ESF1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ESF1 RRM" evidence="7">
        <location>
            <begin position="184"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="6">
        <location>
            <begin position="702"/>
            <end position="724"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="448"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="503"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="640"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="713"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="399"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
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            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="566"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="713"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO98292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="782" mass="87553" checksum="087DB97BAEC2DBD4" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>A4S414</accession>
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    <protein>
        <recommendedName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_26246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
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                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRN3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_001419976.1"/>
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    <dbReference type="STRING" id="436017.A4S414"/>
    <dbReference type="GeneID" id="5004103"/>
    <dbReference type="Gramene" id="ABO98306">
        <property type="protein sequence ID" value="ABO98306"/>
        <property type="gene ID" value="OSTLU_26246"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26246"/>
    <dbReference type="eggNOG" id="KOG2434">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010579_4_0_1"/>
    <dbReference type="OMA" id="YVLCYHM"/>
    <dbReference type="OrthoDB" id="26970at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001042">
        <property type="term" value="F:RNA polymerase I core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001181">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007991">
        <property type="entry name" value="RNA_pol_I_trans_ini_fac_RRN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790:SF0">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IA RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05327">
        <property type="entry name" value="RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="624"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="732"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="624"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="747"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO98306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="761" mass="83244" checksum="EF817BEDAD85B715" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S447</accession>
    <name>A4S447_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_93386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420032.1">
        <property type="nucleotide sequence ID" value="XM_001419995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S447"/>
    <dbReference type="GeneID" id="5003931"/>
    <dbReference type="Gramene" id="ABO98325">
        <property type="protein sequence ID" value="ABO98325"/>
        <property type="gene ID" value="OSTLU_93386"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93386"/>
    <dbReference type="HOGENOM" id="CLU_623165_0_0_1"/>
    <dbReference type="OMA" id="WCTRERT"/>
    <dbReference type="OrthoDB" id="497553at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="440" mass="48230" checksum="2C15EBD33EF1116F" modified="2007-05-15" version="1">MRRGSRFAHQEFCARCARAHRERGVSVTDARLESAMMGLSSAMKFGTSEQDAFASAVAMVTLTLYRFDRIEAEGGEGEGEGEGEGEGEGEGRLSARTLEEARKRVEEDKEAMGMLKYIEMTNKNADEGYTLRRMELERRFASGGEKRTPTPGESIMRMNCKLTLLTREMIELERGITHARRGLEAMEDVDATVDETEIIEIEAQQQLALAWCTRERTPARELAADMLVAFFSVLTNHPVGYREFVRAARSAYEAGISADEITGALDAPEFDVEGTQRGMFGRAADAPKIFAGLVTTAYVAFEAEGLPLPAAAKGDEDLFAYASHPRASDEDAEFQRPTDEDTRRARARGLRKAVEGWMAMDRDELANEVSASLSIDESIDDDAAQPFAGSTTTKSTAPGDGSFAVVRDEAFGASSITLVTLRHQRNIVSFVRNDLAVQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4S457</accession>
    <name>A4S457_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pseudouridine-5'-phosphate glycosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26294</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000590">
        <property type="protein sequence ID" value="ABO98505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420212.1">
        <property type="nucleotide sequence ID" value="XM_001420175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S457"/>
    <dbReference type="STRING" id="436017.A4S457"/>
    <dbReference type="GeneID" id="5004185"/>
    <dbReference type="Gramene" id="ABO98505">
        <property type="protein sequence ID" value="ABO98505"/>
        <property type="gene ID" value="OSTLU_26294"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26294"/>
    <dbReference type="eggNOG" id="KOG3009">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012201_0_1_1"/>
    <dbReference type="OMA" id="GVHREWT"/>
    <dbReference type="OrthoDB" id="198885at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030597">
        <property type="term" value="F:RNA glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="34181" checksum="E1AAC0E1AAAE0062" modified="2007-05-15" version="1">MPRVGDADAPRRRIARLSTHVAPTARADVAVRVSDEVRATLARGGAVVALESTIVAHGMPHPENLETARAVERAVRARGATPATVAIVDGVCVVGATDGELERVARMGTACAKASRRDLSAACGTGKTAATTVSGTMVLARAAGVDVFVTGGIGGVHVGGQDTMDVSADLMELGRTPVAVVCAGAKSILDIPRTLEVLETNGVTVCAYGVDEFPAFFTRSSGCEAPARVDTPLEAAKVIDAGLRLNLNSGSVFAVPIPLEHEALGASIESATARALRETEERGVAGRDVTPYVLKRVAELTGGASLKANIALVMNNAKIGADIACELARLRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4F2</accession>
    <name>A4S4F2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1824 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_43989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420256.1">
        <property type="nucleotide sequence ID" value="XM_001420219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4F2"/>
    <dbReference type="GeneID" id="5004324"/>
    <dbReference type="Gramene" id="ABO98549">
        <property type="protein sequence ID" value="ABO98549"/>
        <property type="gene ID" value="OSTLU_43989"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43989"/>
    <dbReference type="eggNOG" id="ENOG502S97V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2403581_0_0_1"/>
    <dbReference type="OrthoDB" id="39680at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014953">
        <property type="entry name" value="DUF1824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08854">
        <property type="entry name" value="DUF1824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160532">
        <property type="entry name" value="Ava3019-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO98549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="9851" checksum="59477705B7E6ACE6" modified="2007-05-15" version="1">MLGICAASAEEGLAALKTWTAELGLPKGKLHGMDKDGIPVDPPKGAVFIKYNSLSGDAYISGYGGTFRGVLFTPELDDGAFRQYGYLPLDVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4N4</accession>
    <name>A4S4N4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420299.1">
        <property type="nucleotide sequence ID" value="XM_001420262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4N4"/>
    <dbReference type="GeneID" id="5004543"/>
    <dbReference type="Gramene" id="ABO98592">
        <property type="protein sequence ID" value="ABO98592"/>
        <property type="gene ID" value="OSTLU_26472"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26472"/>
    <dbReference type="HOGENOM" id="CLU_2945875_0_0_1"/>
    <dbReference type="OrthoDB" id="10597388at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO98592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="60" mass="7125" checksum="EE5D8BB17857F7FE" modified="2007-05-15" version="1">MKQREAFRRSNAKTHKENERRNAIERQEKRLARWRAGVAMKREYEMKYGGGLGETTARGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4S4Y4</accession>
    <name>A4S4Y4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL29</name>
        <name evidence="6" type="ORF">OSTLU_26572</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420349.1">
        <property type="nucleotide sequence ID" value="XM_001420312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S4Y4"/>
    <dbReference type="STRING" id="436017.A4S4Y4"/>
    <dbReference type="GeneID" id="5004402"/>
    <dbReference type="Gramene" id="ABO98642">
        <property type="protein sequence ID" value="ABO98642"/>
        <property type="gene ID" value="OSTLU_26572"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26572"/>
    <dbReference type="eggNOG" id="KOG3504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169255_2_0_1"/>
    <dbReference type="OMA" id="PRTNKYP"/>
    <dbReference type="OrthoDB" id="996720at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002673">
        <property type="entry name" value="Ribosomal_eL29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01779">
        <property type="entry name" value="Ribosomal_L29e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="57" mass="6376" checksum="71AA62EC16364198" modified="2007-05-15" version="1">MAKSTNHTAHNQSYKNHRNGIKKPKRVGKPSTKGMDPKFLKNQKFAKRGSLKAAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="91" xmlns="https://uniprot.org/uniprot">
    <accession>A4S559</accession>
    <name>A4S559_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal RNA-processing protein 44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_43971</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420386.1">
        <property type="nucleotide sequence ID" value="XM_001420349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S559"/>
    <dbReference type="STRING" id="436017.A4S559"/>
    <dbReference type="GeneID" id="5004500"/>
    <dbReference type="Gramene" id="ABO98679">
        <property type="protein sequence ID" value="ABO98679"/>
        <property type="gene ID" value="OSTLU_43971"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43971"/>
    <dbReference type="eggNOG" id="KOG2102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002333_5_0_1"/>
    <dbReference type="OMA" id="GQVMRNN"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09862">
        <property type="entry name" value="PIN_Rrp44-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000001">
        <property type="entry name" value="Exosome complex exonuclease exoribonuclease (Rrp44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033771">
        <property type="entry name" value="Rrp44_CSD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033770">
        <property type="entry name" value="RRP44_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF35">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RRP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17216">
        <property type="entry name" value="Rrp44_CSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17215">
        <property type="entry name" value="Rrp44_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="PIN" evidence="13">
        <location>
            <begin position="46"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="RNB" evidence="14">
        <location>
            <begin position="483"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABO98679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="962" mass="105897" checksum="8850AA51F91EE5BE" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4S565</accession>
    <name>A4S565_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">OSTLU_88696</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="2"/>
    <dbReference type="EMBL" id="CP000591">
        <property type="protein sequence ID" value="ABO98849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420556.1">
        <property type="nucleotide sequence ID" value="XM_001420519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S565"/>
    <dbReference type="STRING" id="436017.A4S565"/>
    <dbReference type="GeneID" id="5004294"/>
    <dbReference type="Gramene" id="ABO98849">
        <property type="protein sequence ID" value="ABO98849"/>
        <property type="gene ID" value="OSTLU_88696"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_88696"/>
    <dbReference type="eggNOG" id="KOG1936">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025113_3_1_1"/>
    <dbReference type="OMA" id="MDIIGCK"/>
    <dbReference type="OrthoDB" id="1906957at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000054">
        <property type="entry name" value="Histidine--tRNA ligase chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707:SF1">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="77"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABO98849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="525" mass="57636" checksum="46B293EBE21590E2" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5D7</accession>
    <name>A4S5D7_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_26726</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably involved in the biogenesis of the COX complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420588.1">
        <property type="nucleotide sequence ID" value="XM_001420551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5D7"/>
    <dbReference type="STRING" id="436017.A4S5D7"/>
    <dbReference type="GeneID" id="5004826"/>
    <dbReference type="Gramene" id="ABO98881">
        <property type="protein sequence ID" value="ABO98881"/>
        <property type="gene ID" value="OSTLU_26726"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26726"/>
    <dbReference type="eggNOG" id="KOG1563">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1463592_0_0_1"/>
    <dbReference type="OrthoDB" id="10040024at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF2">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO98881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="185" mass="19687" checksum="BBB9D73D83684992" modified="2007-05-15" version="1">MDLARTARVGPRARSVCGVAVPGSLIVTPVRLRAKKKGWFGRGASAAAGEAETVLLLRGWAPDAWTDADAAAGACAKTEGVVRGSERKGRFTPENEPGEDRWFWLDAPALAESRGLPRDAPLIQAIRAGSGDETTYPSAATKEELMRFPVSPEQHSGYAATWFALSAATGALAVVRIRRGVGRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5J0</accession>
    <name>A4S5J0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxypeptidase</fullName>
            <ecNumber evidence="2">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_39506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420780.1">
        <property type="nucleotide sequence ID" value="XM_001420743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5J0"/>
    <dbReference type="MEROPS" id="S10.A47"/>
    <dbReference type="GeneID" id="5004617"/>
    <dbReference type="Gramene" id="ABO99073">
        <property type="protein sequence ID" value="ABO99073"/>
        <property type="gene ID" value="OSTLU_39506"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39506"/>
    <dbReference type="eggNOG" id="KOG1282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008523_9_0_1"/>
    <dbReference type="OMA" id="YQDEMAN"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF201">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006521796" description="Carboxypeptidase" evidence="2">
        <location>
            <begin position="31"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="264" mass="28115" checksum="0AF042DC63E05B5F" modified="2007-05-15" version="1" fragment="single">MTTTRRARATRATAVALFACAVVAPGACDARATTRGTRASVELRREERGGAMARDGDAVTTLPGYGAPPSTQYSGFLDASASTPGTALHYWFAAKRDGDWTRAPTLLWMNGGPGSSSILGFLQEQGPLLVNASGGLMENPFAWTKYANLVALESPAGVGWSYCQEMTVGGDCSNDDVSAARDAAAAVVDFFHRKFPELRSNKFYVTGESYAGVYVPTLARELLDFNDAQTSDDAKIPLAGIATGDPCTDNDSQRNSMSMLWYGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>A4S5X8</accession>
    <name>A4S5X8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DMT family transporter: drug/metabolite</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_17672</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO98980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420687.1">
        <property type="nucleotide sequence ID" value="XM_001420650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S5X8"/>
    <dbReference type="GeneID" id="5004888"/>
    <dbReference type="Gramene" id="ABO98980">
        <property type="protein sequence ID" value="ABO98980"/>
        <property type="gene ID" value="OSTLU_17672"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_17672"/>
    <dbReference type="HOGENOM" id="CLU_824855_0_0_1"/>
    <dbReference type="OMA" id="PVMIKYP"/>
    <dbReference type="OrthoDB" id="498093at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050638">
        <property type="entry name" value="AA-Vitamin_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32322:SF2">
        <property type="entry name" value="EAMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32322">
        <property type="entry name" value="INNER MEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="8">
        <location>
            <begin position="40"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="8">
        <location>
            <begin position="180"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABO98980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="337" mass="36313" checksum="1364819DD0A3790B" modified="2007-05-15" version="1">MATEKDAERGDGTLARRSSLSESFSEHDRGQIVNHAALWTAQLIWALMHVLSHDALEHVEPTAFCALRLALALPFLAISARKEGGSLPWRAVATWVVPMGAMIGAAYLLVFVANARSGPTLVACVQPIMPVSVAVMSYVIGLERMTRVKALGVIVVFAGTVTALRAYEIFQTGGMNFLDIFLLLSQTNSYAVYVVMLGVATKTYPYPLLFLFLATAVAEFVVLLIAIPAFARLDVSRVPASAWGAVVFAGWGSSVFAHSLNSWAVARVKGVLPTVYSGVQVIFTIVLSRVFLRERLPWDRGVGIAVTILGVCLVARAKYAETPDATRRDAPSRSCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4S627</accession>
    <name>A4S627_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_26967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000592">
        <property type="protein sequence ID" value="ABO99163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001420870.1">
        <property type="nucleotide sequence ID" value="XM_001420833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S627"/>
    <dbReference type="STRING" id="436017.A4S627"/>
    <dbReference type="GeneID" id="5004734"/>
    <dbReference type="Gramene" id="ABO99163">
        <property type="protein sequence ID" value="ABO99163"/>
        <property type="gene ID" value="OSTLU_26967"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_26967"/>
    <dbReference type="eggNOG" id="ENOG502QTE9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_279195_0_0_1"/>
    <dbReference type="OMA" id="MAVHFLA"/>
    <dbReference type="OrthoDB" id="1896158at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31110">
        <property type="entry name" value="PESTICIDAL CRYSTAL CRY8BA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31110:SF2">
        <property type="entry name" value="PESTICIDAL CRYSTAL CRY8BA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1130" mass="122455" checksum="6AAE33869943A51E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6Q9</accession>
    <name>A4S6Q9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tafazzin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">OSTLU_7284</name>
        <name evidence="14" type="ORF">OSTLU_7370</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine</text>
            <dbReference type="Rhea" id="RHEA:33731"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64743"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:33732"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:33733"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the taffazin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421134.1">
        <property type="nucleotide sequence ID" value="XM_001421097.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422821.1">
        <property type="nucleotide sequence ID" value="XM_001422784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6Q9"/>
    <dbReference type="STRING" id="436017.A4S6Q9"/>
    <dbReference type="GeneID" id="5004990"/>
    <dbReference type="GeneID" id="5006879"/>
    <dbReference type="Gramene" id="ABO99427">
        <property type="protein sequence ID" value="ABO99427"/>
        <property type="gene ID" value="OSTLU_7370"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01180">
        <property type="protein sequence ID" value="ABP01180"/>
        <property type="gene ID" value="OSTLU_7284"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7284"/>
    <dbReference type="KEGG" id="olu:OSTLU_7370"/>
    <dbReference type="eggNOG" id="KOG2847">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1615127_0_0_1"/>
    <dbReference type="OrthoDB" id="193467at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000872">
        <property type="entry name" value="Tafazzin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497:SF0">
        <property type="entry name" value="TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497">
        <property type="entry name" value="TAZ PROTEIN TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00979">
        <property type="entry name" value="TAFAZZIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="13">
        <location>
            <begin position="8"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO99427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABP01180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="165" mass="18027" checksum="13DD8DFA6F696A70" modified="2007-05-15" version="1" fragment="single">DRANAQGLLTVCNHVSTFDDPGMLSALIPWSVFVGEPRRGGVRWTLCTDEICAKTKLRESFFLCGKALAIKRGGGVEQPAMRTAANLLLRGDWVHLFPEGRVSRDGELGTMRRGVAKLLCDVEIAGGTPPMVLPFWHSGMSDVKPYGRWEIGVGKRVHVTVGEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A4S6T9</accession>
    <name>A4S6T9_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_19192</name>
        <name evidence="2" type="ORF">OSTLU_27238</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000593">
        <property type="protein sequence ID" value="ABO99443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000601">
        <property type="protein sequence ID" value="ABP01164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421150.1">
        <property type="nucleotide sequence ID" value="XM_001421113.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422805.1">
        <property type="nucleotide sequence ID" value="XM_001422768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S6T9"/>
    <dbReference type="STRING" id="436017.A4S6T9"/>
    <dbReference type="GeneID" id="5005210"/>
    <dbReference type="GeneID" id="5006863"/>
    <dbReference type="Gramene" id="ABO99443">
        <property type="protein sequence ID" value="ABO99443"/>
        <property type="gene ID" value="OSTLU_27238"/>
    </dbReference>
    <dbReference type="Gramene" id="ABP01164">
        <property type="protein sequence ID" value="ABP01164"/>
        <property type="gene ID" value="OSTLU_19192"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_19192"/>
    <dbReference type="KEGG" id="olu:OSTLU_27238"/>
    <dbReference type="HOGENOM" id="CLU_310234_0_0_1"/>
    <dbReference type="OrthoDB" id="501822at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 21"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP01164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="949" mass="102712" checksum="0046F1DF2C6FC8F7" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>A4S715</accession>
    <name>A4S715_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_27317</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421193.1">
        <property type="nucleotide sequence ID" value="XM_001421156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S715"/>
    <dbReference type="GeneID" id="5005380"/>
    <dbReference type="Gramene" id="ABO99486">
        <property type="protein sequence ID" value="ABO99486"/>
        <property type="gene ID" value="OSTLU_27317"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27317"/>
    <dbReference type="eggNOG" id="KOG1676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_867115_0_0_1"/>
    <dbReference type="OMA" id="KMIADSW"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="32"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="100"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="174"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="321" mass="34483" checksum="443F156B383DBF07" modified="2007-05-15" version="1">MAVNVAKAAPKSARDDEDAGVVGDGANSKKATYCVEHYDMDVKYEGLIIGPGGATIRKLQQDIGTSIEVVRGEGKLQIKGSREKIEYARKMLDEFFEQKGSKTVKVKCKARSGLIIGNAGQTIKALKEQTGCRIEVMRDVEECVITGPGDRVKVAQAIVEKMIADSWEEGADGDITIVEEVIPCAYKAGAIIGPSGGTIRHIRETTGVAIDIERGADGCKASDQCRIIGTPAQVKKAVEIVHQLLKEMNQAQLQAAPVVPPMYAYGYGTMPNAYAAVPGIPVNSSQMQQIDPQTAAYYAQWQAYYAAQQNTVMPPHPPADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4S792</accession>
    <name>A4S792_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase subfamily 4-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_43238</name>
        <name evidence="6" type="ORF">OSTLU_43286</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421416.1">
        <property type="nucleotide sequence ID" value="XM_001421379.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421447.1">
        <property type="nucleotide sequence ID" value="XM_001421410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S792"/>
    <dbReference type="STRING" id="436017.A4S792"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="GeneID" id="5005312"/>
    <dbReference type="GeneID" id="5005349"/>
    <dbReference type="Gramene" id="ABO99709">
        <property type="protein sequence ID" value="ABO99709"/>
        <property type="gene ID" value="OSTLU_43238"/>
    </dbReference>
    <dbReference type="Gramene" id="ABO99740">
        <property type="protein sequence ID" value="ABO99740"/>
        <property type="gene ID" value="OSTLU_43286"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_43238"/>
    <dbReference type="KEGG" id="olu:OSTLU_43286"/>
    <dbReference type="eggNOG" id="KOG1111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_20_0_1"/>
    <dbReference type="OMA" id="GAMTYCK"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03814">
        <property type="entry name" value="GT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="4">
        <location>
            <begin position="96"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="3">
        <location>
            <begin position="272"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="50181" checksum="E6887E29206A5117" modified="2007-05-15" version="1" fragment="single">MTRAPRASARPRRATTTTTTRATTTTTTGGGIFRPKRRDGDAGRADARSTATRNAAVVVARRRATTRTTATATATTDARPKRRVAIFVEPSPFSHVSGMKNRFLRLIENLREMGDDVVVITPDRDPPKEYHGAKVIGLRGFVLPFYGTDTLLCSFGLDGRVWREFKENKPDLVHCAVPGGMIFGAMTYCKAMDIPLVESYHTHIPHYIPRYTWAGLVKPMWDLIRFWNGYASTTLVTSSILENELRGEGCKNLQVWDKGVDTVAFNPSFKSEEMRKRLSGGRDGPIIGCVGRLGAEKRLGDLKDILAKLPSNVNLAIIGDGPERKRLEEHFAGTNTVFTGMITGDDLSAAYASLDVFVMPSPSETLGFVVMESMASGVPVVAVAAGGLLDILTNPGDVGLLYPEYDYDKAAEHVKMLLENDSERQRMGAASRADVEKWGWMSSNRNLRENQYSKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7E9</accession>
    <name>A4S7E9_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">OSTLU_27455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421441.1">
        <property type="nucleotide sequence ID" value="XM_001421404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7E9"/>
    <dbReference type="STRING" id="436017.A4S7E9"/>
    <dbReference type="GeneID" id="5005305"/>
    <dbReference type="Gramene" id="ABO99734">
        <property type="protein sequence ID" value="ABO99734"/>
        <property type="gene ID" value="OSTLU_27455"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27455"/>
    <dbReference type="eggNOG" id="KOG1448">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048814_0_0_1"/>
    <dbReference type="OrthoDB" id="10263753at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF45">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="3">
        <location>
            <begin position="207"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABO99734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="305" mass="33690" checksum="50DA4D4136024AE6" modified="2007-05-15" version="1">MLFYCTEMEQMAREIAAIDGNIELGEIQWRTFADGFPNIFVNDAEQLHGRHVAFLASFHNASVIFQQLSVIYSLPKMFVASFRLILPFFPTGTFERVDKEGEIPTAVTMARMLSSIPHSRGGPTDMIVFDIHALQERFYFGDSVTPLFASGIPLLLERLASLEDAADVVIAYPDEGACKRFHNFFAKYDEVVCTKVREGDKRIVTIKEGKPTGKHIVIVDDLVQSGGTLIECAKVLRREGASAVSAYVTHGVFPNESWRRFTDPSAGFANFWITDSCPQTVSACSGVAPFVVLKLAGSVAHALNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7W6</accession>
    <name>A4S7W6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoglycolate phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">OSTLU_5787</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Divalent metal ions. Mg(2+) is the most effective.</text>
    </comment>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421347.1">
        <property type="nucleotide sequence ID" value="XM_001421310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7W6"/>
    <dbReference type="STRING" id="436017.A4S7W6"/>
    <dbReference type="GeneID" id="5005431"/>
    <dbReference type="Gramene" id="ABO99640">
        <property type="protein sequence ID" value="ABO99640"/>
        <property type="gene ID" value="OSTLU_5787"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_5787"/>
    <dbReference type="eggNOG" id="KOG2882">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_0_0_1"/>
    <dbReference type="OMA" id="EHFSYCK"/>
    <dbReference type="OrthoDB" id="413953at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO99640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="30801" checksum="6BF2C0CA624304BA" modified="2007-05-15" version="1" fragment="single">ELDEDVDSVVIDCDGVVWNGDALIPGAKAAIEALRAKKKRVFFATNNSTKSRAHYAAKFASLGVDVSKYEIYTSAYAAAMYLKQRRFDEIEDGDDAEPRGEHGERVGDARQKKVYVIGERGVMEEMEEAGIDVEAGVYDSVRCTGRDWEEMEEWLDPENDVGAVVVGSDSAFTFAKLAYASLQIQRGALFIATNPDAGDKIGRALYPGAGAIVNAVATACGEQPEIYCGKPSSFMLDLLCEHTNIDMSRTLVVGDRIDTDIAFGKAGKAGLTALVFTGVTDSEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4S7X6</accession>
    <name>A4S7X6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_7208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000594">
        <property type="protein sequence ID" value="ABO99646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421353.1">
        <property type="nucleotide sequence ID" value="XM_001421316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S7X6"/>
    <dbReference type="STRING" id="436017.A4S7X6"/>
    <dbReference type="GeneID" id="5005245"/>
    <dbReference type="Gramene" id="ABO99646">
        <property type="protein sequence ID" value="ABO99646"/>
        <property type="gene ID" value="OSTLU_7208"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_7208"/>
    <dbReference type="eggNOG" id="KOG3961">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073223_2_0_1"/>
    <dbReference type="OMA" id="IPIKXNS"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019399">
        <property type="entry name" value="Parkin_co-regulated_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207:SF2">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10274">
        <property type="entry name" value="ParcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="195" mass="21527" checksum="F1F3EC16D3515432" modified="2007-05-15" version="1" fragment="single">TRFRQKYDAGEIPARVAHGTGANAIAWRVDPSALDASAYLPLFIDGLKETKHPYRLLAVRGGIELTRACGERALLDALPRSVLPMKEALGTGDMAVTAVALELLREFVKVSPSIGEALVPYYRNLLPALNALKDVSDVYVSLVNLTDCRSWREPHRRSRRNIGSLVRATLRALERRGGADALVNIKYQIPTYQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4S818</accession>
    <name>A4S818_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_27694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421684.1">
        <property type="nucleotide sequence ID" value="XM_001421647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S818"/>
    <dbReference type="GeneID" id="5005821"/>
    <dbReference type="Gramene" id="ABO99977">
        <property type="protein sequence ID" value="ABO99977"/>
        <property type="gene ID" value="OSTLU_27694"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27694"/>
    <dbReference type="eggNOG" id="ENOG502SRBK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100782_0_0_1"/>
    <dbReference type="OMA" id="DANAFVM"/>
    <dbReference type="OrthoDB" id="203880at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO99977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27421" checksum="43C93050FCE09E04" modified="2007-05-15" version="1">MAQRWYAASEARYLSTTDEQPLVEAREDFLDFKRYGDLKECALKHPKLRVKGGLNDAGFSKTRGFVVKFNLEGVDKFKASPDYECFASVFDELRLPDANAFVMNILLCELGDYDAYNAEELSVGLHLDTTVGIYSRHMFIAHQVSVLYNSVPNDMVGGELELFPYGDGYPDTGAAPEKKIRPKENMLVNFRGDAFHQVRSYKTRSGSERVSLVLEQYVIDDDAYGKTMRFFEAFKSNMTMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="104" xmlns="https://uniprot.org/uniprot">
    <accession>A4S895</accession>
    <name>A4S895_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Regulator of telomere elongation helicase 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">OSTLU_40695</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421725.1">
        <property type="nucleotide sequence ID" value="XM_001421688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S895"/>
    <dbReference type="STRING" id="436017.A4S895"/>
    <dbReference type="GeneID" id="5005862"/>
    <dbReference type="Gramene" id="ABP00019">
        <property type="protein sequence ID" value="ABP00019"/>
        <property type="gene ID" value="OSTLU_40695"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_40695"/>
    <dbReference type="eggNOG" id="KOG1132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006515_4_1_1"/>
    <dbReference type="OMA" id="NCATIVA"/>
    <dbReference type="OrthoDB" id="19182at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904430">
        <property type="term" value="P:negative regulation of t-circle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010569">
        <property type="term" value="P:regulation of double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090657">
        <property type="term" value="P:telomeric loop disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000431">
        <property type="entry name" value="Regulator of telomere elongation helicase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057498">
        <property type="entry name" value="Rtel1_ARCH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF34">
        <property type="entry name" value="REGULATOR OF TELOMERE ELONGATION HELICASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23109">
        <property type="entry name" value="ARCH_RTEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="19"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00073810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABP00019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="749" mass="83209" checksum="46BF6A28C835C7D2" modified="2007-05-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8A4</accession>
    <name>A4S8A4_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421588.1">
        <property type="nucleotide sequence ID" value="XM_001421551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8A4"/>
    <dbReference type="GeneID" id="5005669"/>
    <dbReference type="Gramene" id="ABO99881">
        <property type="protein sequence ID" value="ABO99881"/>
        <property type="gene ID" value="OSTLU_18317"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18317"/>
    <dbReference type="HOGENOM" id="CLU_623166_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABO99881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="440" mass="48024" checksum="E6ADF7C8773ADA25" modified="2007-05-15" version="1">MASATTKATRRRLSWRDALDETRTYDDDDGDGAKDGWARRGGAADEENATARRAKGQKTSASPRRALAAVDANATMTSPTTRCNTFLAGSTPGAMSAKHASRVRALVEVDEPEEEAEVAEISFDFEDESAMMSPASVDDAELESDSTGDVTVVMSSKRGRLSRVNETFNVFKSLAQLAISPSELDVSKRRAPTPMNTPATTLTFDDDVDSPVVQARTEADLRDTVEKIASSLVDVEDVMSSYTTRVRAHRVAKALGAAIFMLAISARLYFAWNVAIAAFRPRYAIDGTAFAYRWFWRSRTNWNVPFAFAGYASYGEFMIQRALDVESRRAMTRAAAFRAAVSATRRVAVVLAYISGVFGIFGVVAKASEDPHPGETTKRGATSPFVFVPKVMMMMTTTTDPERPRRPSFGASAVLDTSDRTSSTHREMDGEADEFAVVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8D1</accession>
    <name>A4S8D1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABP00042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421748.1">
        <property type="nucleotide sequence ID" value="XM_001421711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8D1"/>
    <dbReference type="GeneID" id="5005685"/>
    <dbReference type="Gramene" id="ABP00042">
        <property type="protein sequence ID" value="ABP00042"/>
        <property type="gene ID" value="OSTLU_27806"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27806"/>
    <dbReference type="eggNOG" id="ENOG502SU7H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_916420_0_0_1"/>
    <dbReference type="OMA" id="VWSIARV"/>
    <dbReference type="OrthoDB" id="10442068at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="304" mass="34937" checksum="49303864A8A882D9" modified="2007-05-15" version="1">MRKRRARELTKRWLLLVLVCGSFLFAFLYPLPETKSSVHTVVILTVGNDRKLDDLHRLARDTVFSNTRSARISAQVLVYEGKFRPWFNTSTADDATVVQASREVERLRYGSHSFELFSGIYGASVKPRALRWLTQPDQAWIDFGWIIEPDVVFTGSWQTLFEKYESDSSDLIAFNTTFRYSNKTAWNHWPSCTYCRGLPNWCKQSALLPAFRISRNFAAAAVAHLSTSTRSSGHHEAFLPTFLTVNSDTFSFRDLGPDVAYMRWRPAFDFDAVPRLAPIRRDALYHPVKSLEMYRNLSQASLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8L3</accession>
    <name>A4S8L3_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_27889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421642.1">
        <property type="nucleotide sequence ID" value="XM_001421605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8L3"/>
    <dbReference type="GeneID" id="5005724"/>
    <dbReference type="Gramene" id="ABO99935">
        <property type="protein sequence ID" value="ABO99935"/>
        <property type="gene ID" value="OSTLU_27889"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27889"/>
    <dbReference type="HOGENOM" id="CLU_1621741_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO99935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18259" checksum="FED539CC20B84C96" modified="2007-05-15" version="1">MRASRGDDAPALPGRAVAVDEDKKSIDNDANKRAVKRYRDRQRDAKMKLESENAALRVETTRLATELAHARWVLDAVASRCGMKRRATGRDADAALRRSVARVIHGAGCPLGHQGRDRPFRLDATEARRREDEDEDELAAFLKEFLVHEDGKCPCPGRARDGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>A4S8M4</accession>
    <name>A4S8M4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pseudouridine synthase I TruA alpha/beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_27900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000595">
        <property type="protein sequence ID" value="ABO99942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421649.1">
        <property type="nucleotide sequence ID" value="XM_001421612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S8M4"/>
    <dbReference type="STRING" id="436017.A4S8M4"/>
    <dbReference type="GeneID" id="5005758"/>
    <dbReference type="Gramene" id="ABO99942">
        <property type="protein sequence ID" value="ABO99942"/>
        <property type="gene ID" value="OSTLU_27900"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_27900"/>
    <dbReference type="eggNOG" id="KOG2553">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023331_0_0_1"/>
    <dbReference type="OMA" id="FQARREC"/>
    <dbReference type="OrthoDB" id="10256309at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF9">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="374"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="289"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO99942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="556" mass="62155" checksum="A175B8DDB1181AF1" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A4S903</accession>
    <name>A4S903_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001421981.1">
        <property type="nucleotide sequence ID" value="XM_001421944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S903"/>
    <dbReference type="STRING" id="436017.A4S903"/>
    <dbReference type="GeneID" id="5005877"/>
    <dbReference type="Gramene" id="ABP00275">
        <property type="protein sequence ID" value="ABP00275"/>
        <property type="gene ID" value="OSTLU_28030"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28030"/>
    <dbReference type="HOGENOM" id="CLU_1663660_0_0_1"/>
    <dbReference type="OrthoDB" id="10469126at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="159" mass="17202" checksum="639CD98CAD2B5A25" modified="2007-05-15" version="1">MLDETTTETGLTTAQGEELRRRWGAMASALATTGESNAAKQSALNETSRRNAITEIAGRAKIGAKEFESLKSVAPERRIAEVLLTIPRGAERAAAVEDALTPPADGEDLGGDEENEDVFTTAPRLLNVLEGMARERRTDGEDDSELCELIEIVERKCDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S955</accession>
    <name>A4S955_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422005.1">
        <property type="nucleotide sequence ID" value="XM_001421968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S955"/>
    <dbReference type="GeneID" id="5005905"/>
    <dbReference type="Gramene" id="ABP00299">
        <property type="protein sequence ID" value="ABP00299"/>
        <property type="gene ID" value="OSTLU_18525"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18525"/>
    <dbReference type="eggNOG" id="ENOG502QRMN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1108582_0_0_1"/>
    <dbReference type="OMA" id="ANDGPER"/>
    <dbReference type="OrthoDB" id="498975at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36383">
        <property type="entry name" value="OS09G0529350 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36383:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="251" mass="26196" checksum="CD2B9EBDF3A595CA" modified="2007-05-15" version="1">MASDASVRAEAERAGRDARDVAAREIEKVEQMERERVRTTFEEVQMKTEASQSKAERAAEETLALKRDAVERAEAKMRALDAERAALREELAKEDASGGNGAGDKWADGTSIDEAAEKAESAKSAAVGGASGALLATPLIVSQGGGLVSIGIVAVSCAVFGVTYRYAVRRDLGNNELKGGVVGAFGLARGLSAADVYLRAASLNGDADFATYAQAALLAGQGVLTYAFAALALEQAFARGILKPFGEPPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9G0</accession>
    <name>A4S9G0_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">OSTLU_47791</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000596">
        <property type="protein sequence ID" value="ABP00353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422059.1">
        <property type="nucleotide sequence ID" value="XM_001422022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9G0"/>
    <dbReference type="STRING" id="436017.A4S9G0"/>
    <dbReference type="GeneID" id="5006099"/>
    <dbReference type="Gramene" id="ABP00353">
        <property type="protein sequence ID" value="ABP00353"/>
        <property type="gene ID" value="OSTLU_47791"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_47791"/>
    <dbReference type="eggNOG" id="KOG3163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1070048_0_0_1"/>
    <dbReference type="OMA" id="TNTPEND"/>
    <dbReference type="OrthoDB" id="1847590at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 16"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11381">
        <property type="entry name" value="NSA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.310:FF:000001">
        <property type="entry name" value="NSA2, ribosome biogenesis homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039411">
        <property type="entry name" value="NSA2_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12642">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABP00353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="260" mass="29839" checksum="E0B0F8950852E674" modified="2007-05-15" version="1">MPQNEHIELFQKRYGKRLDHEERTRKKEAREPHKRSQVAKKLIGLKAKLYAKKRHKEKVEMKKTINSHSERNNKHKVEEKAQPGAIPAYLMDREQTSRAKVLSNTVKQKRKEKAGKWEVPLPKVRPVAEDEMFKVMRSGKRMKKSWKRMITKATFVGPGFTRKPPKYERFIRPSGLRFTKAHITHPELKATFQLEILGVKKNPNGPMYSSLGVLTKGTIIEVNVSELGLVTPGGKVVWGKYAQITNNPENDGCVNGVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9M1</accession>
    <name>A4S9M1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_93917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422196.1">
        <property type="nucleotide sequence ID" value="XM_001422159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9M1"/>
    <dbReference type="STRING" id="436017.A4S9M1"/>
    <dbReference type="GeneID" id="5006253"/>
    <dbReference type="Gramene" id="ABP00513">
        <property type="protein sequence ID" value="ABP00513"/>
        <property type="gene ID" value="OSTLU_93917"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_93917"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_746774_0_0_1"/>
    <dbReference type="OMA" id="RYEYRRD"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF14">
        <property type="entry name" value="PROTEIN DNAJ, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="65"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="371" mass="39933" checksum="50EF94F5BA73254C" modified="2007-05-15" version="1">MRRVASRVGKRASGARPARASDAARVASRVREATRGATDDFQRRDGNARRRESARAYAASTIEDDPHALLGVARGASADEVKRAYRREALKWHPDRHQGDAKARAEARFKRISAAYQALSAPGGGERRARASGGGGRGGGAEDFARRARAANARRGGETPGGYGYEYRRDFTREDAERVFREMFGNDSSSFIRELERAMREAATRGRAPGFGAPGFGAPGFGAGGFAFGRGMSAYDLNDLFKTLFSEQVANEISETSYVNARGETVIRRVVRSRAPNGVVSESVTERVVGRGGGAQDPWRQQSTSAGAARGARAPPPPGSVVGVNPLVELAVGAARVARIAFVRFVATFGARILQQIIRFILRRIFGGGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4S9R2</accession>
    <name>A4S9R2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FG-GAP repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_89512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422217.1">
        <property type="nucleotide sequence ID" value="XM_001422180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4S9R2"/>
    <dbReference type="GeneID" id="5006274"/>
    <dbReference type="Gramene" id="ABP00534">
        <property type="protein sequence ID" value="ABP00534"/>
        <property type="gene ID" value="OSTLU_89512"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89512"/>
    <dbReference type="eggNOG" id="ENOG502QPN1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011646_0_0_1"/>
    <dbReference type="OrthoDB" id="498961at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34284">
        <property type="entry name" value="FG-GAP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34284:SF1">
        <property type="entry name" value="FG-GAP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="52847" checksum="043F552A5CAAB78D" modified="2007-05-15" version="1" fragment="single">VDEVEREVLEDEEGGEFEYYAFDARTGARRWTETSGEDEHRRRARARLSLRNLDDDEIDGAVERACRDFRESIVQDGLPHLWRHPVDTKMRLAHFRRHKSRANAMARDKASAGKRKRGAAAAKAVPSNAATRAFGRALDALKGESKRRLDDDDAHPPHASTHARRVRKREPPNVVVSHHAEGIDVLHLYSGVKVCEMKLKSPGLHVDLDGDGVVDHVEAHGRNLRSAEDIPHCWATVTSGVPDEGRTLSASICRGGSGLAGHRAAQAAGRDIRAVEVVSPISLRRLPETSSELAKPLDRMGRDAIFLNSRGEMTCYNARDGEQKRWQIRTTADWTPSDDVVKPSLTSFPIRVDGYLDLAIATGASSMVIVNSKGYRATAPIELPSPPAAPLVARDVDGDGFTDLVLHTKSGVYVWIQTPRAGNLPFTFLIGALAASASLALVLRLRDAPDAVARRDASFVVRARASSRPSSSSGDDDVPSDADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA10</accession>
    <name>A4SA10_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine-S-conjugate beta-lyase</fullName>
            <ecNumber evidence="2">4.4.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">OSTLU_28388</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.13" evidence="2"/>
    <dbReference type="EMBL" id="CP000597">
        <property type="protein sequence ID" value="ABP00476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422159.1">
        <property type="nucleotide sequence ID" value="XM_001422122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA10"/>
    <dbReference type="STRING" id="436017.A4SA10"/>
    <dbReference type="GeneID" id="5006323"/>
    <dbReference type="Gramene" id="ABP00476">
        <property type="protein sequence ID" value="ABP00476"/>
        <property type="gene ID" value="OSTLU_28388"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28388"/>
    <dbReference type="eggNOG" id="KOG0257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_15_0_1"/>
    <dbReference type="OMA" id="HIRINIG"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 17"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051798">
        <property type="entry name" value="Class-II_PLP-Dep_Aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43525">
        <property type="entry name" value="PROTEIN MALY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43525:SF1">
        <property type="entry name" value="PROTEIN MALY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="27"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABP00476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="389" mass="43228" checksum="6382FC1006649FA8" modified="2007-05-15" version="1">MSRKWDRFASRGDPTPLWVADMDFSAPRAVVDAVTAIARAGHYGYADPDDAVTEAATARFRERHGVADANANALRWLPGLNPGLNHAVRAARRARGGRAVVTAVCTPIYPPFLHASRNDESARVEVALRRAIEDGRARYSIDWEALETALAREDVGLLLWCNPHNPVGRVWTRDEMVRVARLCVKHDVVLCSDEVWRELILDEKATPFCGAGSILDEVDGLRERLIIMTSPSKTYNVAGCDVAMAYIADKALRLHFARAGSDKAEITPFGYAATLAAYTDPSCEEWRQRLLTYLRANRDHIDAALSDDANARELMTWTVPDASYLMWLNCEKLVDRVERSPFEHFIEHGVALSDGAPFSAPLSARINFATRRDILDQGLDSIVTALERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA63</accession>
    <name>A4SA63_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_28443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422292.1">
        <property type="nucleotide sequence ID" value="XM_001422255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA63"/>
    <dbReference type="GeneID" id="5006381"/>
    <dbReference type="Gramene" id="ABP00609">
        <property type="protein sequence ID" value="ABP00609"/>
        <property type="gene ID" value="OSTLU_28443"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28443"/>
    <dbReference type="eggNOG" id="ENOG502S88X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_730340_0_0_1"/>
    <dbReference type="OrthoDB" id="9991036at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="201"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="379" mass="42447" checksum="6596A31EFD0D060B" modified="2007-05-15" version="1">MRNKRRTRRLRITVISITLASSMSFIMYRSLSSSSSSLKTHRDDVSPLERSIADVVRDLKATRERVLRDVLATAVSTDTTDAREVENSSPIADALDQAKRIIENFDRAGRSNAREDEAESLETLRSVVESVSDVQRLAANPNSPVVRRAKKRSELFNRIHDANLWGSAESRSGGGSTKATTSTAARCIGEWIRKYDIKTFLDLPCGDANWQAGIPGIENVRYTGMDISVGALETAKTRMSEVQTDIDDFRTHDIVALPMRQRYDAIMHRDVVQHLSYEEALRGLSNFAKSGSTYFIVSTHPKSTERGVESDVGVARDIGYTYQNNMQSEPFNFPPPLEMCDNYANNDASKIAIWRIADLPNFERKLAHISTHESGARKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA67</accession>
    <name>A4SA67_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_28447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422327.1">
        <property type="nucleotide sequence ID" value="XM_001422290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA67"/>
    <dbReference type="GeneID" id="5006384"/>
    <dbReference type="Gramene" id="ABP00644">
        <property type="protein sequence ID" value="ABP00644"/>
        <property type="gene ID" value="OSTLU_28447"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28447"/>
    <dbReference type="HOGENOM" id="CLU_2965109_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="59" mass="6783" checksum="A54F99AA95882392" modified="2007-05-15" version="1">MIALSECVSADELTCANIDIVLRFLKADSFQAVFTLQKQIYAAAFWTIRNLRTLYRILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>A4SA92</accession>
    <name>A4SA92_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_18822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000598">
        <property type="protein sequence ID" value="ABP00661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422344.1">
        <property type="nucleotide sequence ID" value="XM_001422307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SA92"/>
    <dbReference type="CAZy" id="GT17">
        <property type="family name" value="Glycosyltransferase Family 17"/>
    </dbReference>
    <dbReference type="GeneID" id="5006401"/>
    <dbReference type="Gramene" id="ABP00661">
        <property type="protein sequence ID" value="ABP00661"/>
        <property type="gene ID" value="OSTLU_18822"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_18822"/>
    <dbReference type="HOGENOM" id="CLU_623167_0_0_1"/>
    <dbReference type="OrthoDB" id="6474464at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003830">
        <property type="term" value="F:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006813">
        <property type="entry name" value="Glyco_trans_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224:SF0">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04724">
        <property type="entry name" value="Glyco_transf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="440" mass="49377" checksum="21D0F34735541CAF" modified="2007-05-15" version="1">MRQLRAFQIVAFVVVTLTYAYVHLYVDFDFPRELVRITGVTVNGTVGDQSESIDASVSETADENTPRAFNEPLAPSSDLCEELVRISSDHRRVIELLTRAQFPSALSPTDYDDSSIALQPASSVQFECDAGKTLDEPRNIVDVFLFGGGEVDTLEIRLYELHPVVDKFIAVTSNVTHKGEATFDALESLLQTARFESIRDKVEIFKHAQAGAAAPNGVNFQFEAEKESAIARELAKRYDEKTLVIFGHVDEIPAREDVWKAARCETALPGNFGIWFPYGNLNFAFRSDFPARNMPWTLGDPGVTVANRLDQMLLPRGRMEHVLGRGFHATNYCFPPQYILKMMTATEYGGFDDFIGNIKSGTNKTCEQTMQELRLFCLNDPVRAYGARMRRVDELVKAGENAEQFYTPLALRLSNMTRYPSWDPTGQAIDQRATILPGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAG8</accession>
    <name>A4SAG8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PRELI/MSF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000599">
        <property type="protein sequence ID" value="ABP00702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422385.1">
        <property type="nucleotide sequence ID" value="XM_001422348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAG8"/>
    <dbReference type="GeneID" id="5006443"/>
    <dbReference type="Gramene" id="ABP00702">
        <property type="protein sequence ID" value="ABP00702"/>
        <property type="gene ID" value="OSTLU_28565"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28565"/>
    <dbReference type="HOGENOM" id="CLU_1028155_0_0_1"/>
    <dbReference type="OMA" id="FMACERE"/>
    <dbReference type="OrthoDB" id="10525266at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 19"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABP00702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="29893" checksum="3732AB845D2788DB" modified="2007-05-15" version="1">MVKLCVDSPALDVDAATLWRARTTSLFMTCERAVFGDLERSVVLYERCRHDENRARCVIRTKLDAKLPYMARRALGVKSSRDAVVMYDDVTLEETQSTGPYLFEASSRTYGTFLNPENSVLKGTVLCKSVDDGSMLSVRLECAVKMTGIGSAIERTIVSGMKTKFALYPKVIELYKAKLRENEAKRRERDEERAAKASIDACADACEFHSARDSDSERDDVAPSLADDRVADAKKGDATSPIATGCCVPASRRRSRSSNSNSNAAPVKRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAQ2</accession>
    <name>A4SAQ2_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Oxidized purine nucleoside triphosphate hydrolase</fullName>
            <ecNumber evidence="13">3.6.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">2-hydroxy-dATP diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">7,8-dihydro-8-oxoguanine triphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">8-oxo-dGTPase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Methylated purine nucleoside triphosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Nucleoside diphosphate-linked moiety X motif 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">OSTLU_29340</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Oxidized purine nucleoside triphosphate hydrolase which is a prominent sanitizer of the oxidized nucleotide pool. Catalyzes the hydrolysis of 2-oxo-dATP (2-hydroxy-dATP) into 2-oxo-dAMP. Also has a significant hydrolase activity toward 2-oxo-ATP, 8-oxo-dGTP and 8-oxo-dATP. Through the hydrolysis of oxidized purine nucleoside triphosphates, prevents their incorporation into DNA and the subsequent transversions A:T to C:G and G:C to T:A. Also catalyzes the hydrolysis of methylated purine nucleoside triphosphate preventing their integration into DNA. Through this antimutagenic activity protects cells from oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2-oxo-ATP + H2O = 2-oxo-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67392"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71395"/>
            <dbReference type="ChEBI" id="CHEBI:172878"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:67393"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2-oxo-dATP + H2O = 2-oxo-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31583"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:63212"/>
            <dbReference type="ChEBI" id="CHEBI:77897"/>
            <dbReference type="EC" id="3.6.1.56"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:31584"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>8-oxo-dATP + H2O = 8-oxo-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:65396"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71361"/>
            <dbReference type="ChEBI" id="CHEBI:172871"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:65397"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>8-oxo-dGTP + H2O = 8-oxo-dGMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31575"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:63224"/>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:31576"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>N(6)-methyl-ATP + H2O = N(6)-methyl-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67608"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
            <dbReference type="ChEBI" id="CHEBI:172873"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:67609"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>N(6)-methyl-dATP + H2O = N(6)-methyl-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:169976"/>
            <dbReference type="ChEBI" id="CHEBI:172872"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:67605"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>O(6)-methyl-dGTP + H2O = O(6)-methyl-dGMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67600"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:169974"/>
            <dbReference type="ChEBI" id="CHEBI:169975"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:67601"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.56" evidence="13"/>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422472.1">
        <property type="nucleotide sequence ID" value="XM_001422435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAQ2"/>
    <dbReference type="STRING" id="436017.A4SAQ2"/>
    <dbReference type="GeneID" id="5006707"/>
    <dbReference type="Gramene" id="ABP00789">
        <property type="protein sequence ID" value="ABP00789"/>
        <property type="gene ID" value="OSTLU_29340"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29340"/>
    <dbReference type="eggNOG" id="ENOG502S254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_11_1_1"/>
    <dbReference type="OMA" id="MIEATLC"/>
    <dbReference type="OrthoDB" id="408303at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008413">
        <property type="term" value="F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008828">
        <property type="term" value="F:dATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03427">
        <property type="entry name" value="NUDIX_MTH1_Nudt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003563">
        <property type="entry name" value="8ODP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758">
        <property type="entry name" value="7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758:SF2">
        <property type="entry name" value="OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01403">
        <property type="entry name" value="8OXTPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="24">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00032071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00053094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ABP00789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="184" mass="21130" checksum="0E82EF2059F37504" modified="2007-05-15" version="1">MPREVREGDIALARGAAHRAFTLVVVRDYEGGRVLLGEKLRGFGAGYYNGFGGKVERGETVEAAAARELTEEANVEATNMTRRGALRFVFDDKPLEPWLVHVFHCSRYDGEIAASDEMRPEWFDLDDVPFENMWADDPYWWPLFLEEKEFVGTFTFTNTTTLVDYWIRETKDLMLDVEAMTANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAR8</accession>
    <name>A4SAR8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">OSTLU_94057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422655.1">
        <property type="nucleotide sequence ID" value="XM_001422618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAR8"/>
    <dbReference type="GeneID" id="5006541"/>
    <dbReference type="Gramene" id="ABP00972">
        <property type="protein sequence ID" value="ABP00972"/>
        <property type="gene ID" value="OSTLU_94057"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_94057"/>
    <dbReference type="eggNOG" id="KOG1454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_957761_0_0_1"/>
    <dbReference type="OMA" id="SSPREIW"/>
    <dbReference type="OrthoDB" id="498673at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689:SF1">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="7"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABP00972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="291" mass="31029" checksum="6ACD63523A7ACB7C" modified="2007-05-15" version="1">MRRASEALDAEVVAHDSCGFGLTARPRDVKKYTRASDAKACRAIAREVGGDAAARSLTLMGHSLGAVGAALAAAQGGVDYVVLVAPAIIGGKLRKNDAGDDAALSLPTFVRVAFAAVGAAAATAAWCLTCAVKPFLILLLRKLVRSKEFWTKGLRAAIDPSRVDAMASDWIDGYRKPSVVRDWDVGMFRVVLASVVAASSPREIWRDAMARARATTQPSTLEREDAVNALVESGAKILIVHGENDVIVPASNSRTLAKLLNCELRILPKCGHMPHEESPEAFIDVLRDFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAU4</accession>
    <name>A4SAU4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_89681</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422500.1">
        <property type="nucleotide sequence ID" value="XM_001422463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAU4"/>
    <dbReference type="STRING" id="436017.A4SAU4"/>
    <dbReference type="GeneID" id="5006558"/>
    <dbReference type="Gramene" id="ABP00817">
        <property type="protein sequence ID" value="ABP00817"/>
        <property type="gene ID" value="OSTLU_89681"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_89681"/>
    <dbReference type="eggNOG" id="KOG1184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_3_1_1"/>
    <dbReference type="OMA" id="DFRHEEP"/>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02002">
        <property type="entry name" value="TPP_BFDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF86">
        <property type="entry name" value="ACETOLACTATE SYNTHASE LARGE SUBUNIT ILVX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="357"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABP00817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="652" mass="69550" checksum="78B287CD91B130BA" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>A4SAX6</accession>
    <name>A4SAX6_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000600">
        <property type="protein sequence ID" value="ABP00832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001422515.1">
        <property type="nucleotide sequence ID" value="XM_001422478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4SAX6"/>
    <dbReference type="STRING" id="436017.A4SAX6"/>
    <dbReference type="GeneID" id="5006573"/>
    <dbReference type="Gramene" id="ABP00832">
        <property type="protein sequence ID" value="ABP00832"/>
        <property type="gene ID" value="OSTLU_29413"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29413"/>
    <dbReference type="eggNOG" id="KOG4828">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1899000_0_0_1"/>
    <dbReference type="OMA" id="HTEFLIT"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10178">
        <property type="entry name" value="PAC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABP00832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="154" mass="16547" checksum="4A41E0DC788B7687" modified="2007-05-15" version="1">MFPPRAGQCACVIDGAHTEFLITEYADRVLVVATQIGKLGTVFHLSRSQSVELSDPSYEDDGETMDDATASMDTVIARTVIGRRDDDALRACARRIADVLFTEGLEKPIVCALGLRSDASLEAKRAVARVAVERGRELLAASRAAEGSGSRSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQP6</accession>
    <name>A4RQP6_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA repair protein RAD50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">OSTLU_28736</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415771.1">
        <property type="nucleotide sequence ID" value="XM_001415734.1"/>
    </dbReference>
    <dbReference type="STRING" id="436017.A4RQP6"/>
    <dbReference type="GeneID" id="4999395"/>
    <dbReference type="Gramene" id="ABO94063">
        <property type="protein sequence ID" value="ABO94063"/>
        <property type="gene ID" value="OSTLU_28736"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28736"/>
    <dbReference type="eggNOG" id="KOG0962">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006184_0_0_1"/>
    <dbReference type="OMA" id="FSDYYYR"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000593">
        <property type="entry name" value="DNA repair protein RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004584">
        <property type="entry name" value="Rad50_eukaryotes"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00606">
        <property type="entry name" value="rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="14 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="17" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="21">
        <location>
            <begin position="6"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="760"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="904"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="288"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="428"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="577"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="774"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="913"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ABO94063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="1313" mass="148397" checksum="3A9E788FA68A0BAD" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQZ1</accession>
    <name>A4RQZ1_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Actin-related protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Actin-like protein 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARP3501</name>
        <name evidence="10" type="ORF">OSTLU_39896</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CCE9901</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415475.1">
        <property type="nucleotide sequence ID" value="XM_001415438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQZ1"/>
    <dbReference type="STRING" id="436017.A4RQZ1"/>
    <dbReference type="GeneID" id="4999699"/>
    <dbReference type="Gramene" id="ABO93767">
        <property type="protein sequence ID" value="ABO93767"/>
        <property type="gene ID" value="OSTLU_39896"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39896"/>
    <dbReference type="eggNOG" id="KOG0678">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_3_0_1"/>
    <dbReference type="OMA" id="GIHYPIR"/>
    <dbReference type="OrthoDB" id="421448at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009825">
        <property type="term" value="P:multidimensional cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010090">
        <property type="term" value="P:trichome morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd10221">
        <property type="entry name" value="ASKHA_NBD_Arp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000029">
        <property type="entry name" value="Actin-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000006">
        <property type="entry name" value="Actin-related protein 3 (ARP3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABO93767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="416" mass="46131" checksum="BC1D27ADE1D72FEF" modified="2007-05-15" version="1">MSSDAHTRPAVVIDNGTGYTKMGFAKNVNPTHVIPTCVAENAPASASKRRGAMDDLDFAIGDEAMALSGSRDVRWPIRHGQVENWEHMEKFWEASICRYLRCDPEDHYFLLTEPPLNPPENREYTAEIMFESFNAPGMYIGVQAVLALAASIASKKQSQYASALTGTVIDIGDGVTHVIPVSDGYVLGSSIKSVPLAGRDLTTFVQYLMRERGERVPPEDAMEVARKVKEDYCYVCKDVVKEFLQHERMPGEYVVQIHGVRGKTGDTWTADVGYERFLAPEVFFEPEIYSSDYITPLPELVHQAIASSPIDTRRNLYGNIVLSGGSTMFKGFGKRIKRDVKRLVDGRIAATTKGATFESKEVEVEVVTHNFQRTAVWFGGSVLASTPGFYSSCVTKAEYEEKGASVVRQNPVFRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>A4RR30</accession>
    <name>A4RR30_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein FAM136A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_28872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM136 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415498.1">
        <property type="nucleotide sequence ID" value="XM_001415461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RR30"/>
    <dbReference type="GeneID" id="4999810"/>
    <dbReference type="Gramene" id="ABO93790">
        <property type="protein sequence ID" value="ABO93790"/>
        <property type="gene ID" value="OSTLU_28872"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_28872"/>
    <dbReference type="eggNOG" id="KOG3377">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110442_1_0_1"/>
    <dbReference type="OMA" id="QADMHRC"/>
    <dbReference type="OrthoDB" id="9975421at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008560">
        <property type="entry name" value="DUF842_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21096">
        <property type="entry name" value="PROTEIN FAM136A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21096:SF0">
        <property type="entry name" value="PROTEIN FAM136A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05811">
        <property type="entry name" value="DUF842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="14369" checksum="71C64279D7209B5B" modified="2007-05-15" version="1">MEDLQKNIVKIQDDLDLKVFRPLQKRAFDASSKCCDGDKSRESFQACLERAGQATSQAEHAVMQTLGQFQQRVQRCVVQCQDKAQSIVEAKGVEKAQAQMESCANDCGKFYVKELNSIGAKLMKEHKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRH1</accession>
    <name>A4RRH1_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415900.1">
        <property type="nucleotide sequence ID" value="XM_001415863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRH1"/>
    <dbReference type="GeneID" id="4999503"/>
    <dbReference type="Gramene" id="ABO94192">
        <property type="protein sequence ID" value="ABO94192"/>
        <property type="gene ID" value="OSTLU_29015"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29015"/>
    <dbReference type="HOGENOM" id="CLU_1032041_0_0_1"/>
    <dbReference type="OrthoDB" id="28939at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009563">
        <property type="entry name" value="SSSCA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051888">
        <property type="entry name" value="UPF0148_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537:SF1">
        <property type="entry name" value="PROTEIN ZNRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537">
        <property type="entry name" value="SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06677">
        <property type="entry name" value="Auto_anti-p27"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="270" mass="29027" checksum="B5B5E1AE5A4BE65F" modified="2007-05-15" version="1">MSDASARIAARLLRGWTLTAERCPVARCGTPLMRERATDATFYCAGGDASVRLDDVEHGARSGAVDAWEAESDEDEDARDRDGARAREVGTSEEEDGDADDARSPSAREDATRIDGGIDGLVLRDGVVDVSGRVAEKMLMGWTLTNDVCPVSSCSAPLVRNRAGESFCVRHEMFVRKGESATRAMGATVSAPKPPPGTAAARDGKSRVGRQSRVDDEIEESSLRTLRALEEKLAQARGALRDETDVDKCRSWLAFIDELHGSMRALSGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRK8</accession>
    <name>A4RRK8_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glycerophosphodiester phosphodiesterase</fullName>
            <ecNumber evidence="1">3.1.4.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">OSTLU_4812</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a sn-glycero-3-phosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12969"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:83408"/>
            <dbReference type="EC" id="3.1.4.46"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.46" evidence="1"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415920.1">
        <property type="nucleotide sequence ID" value="XM_001415883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRK8"/>
    <dbReference type="STRING" id="436017.A4RRK8"/>
    <dbReference type="GeneID" id="4999435"/>
    <dbReference type="Gramene" id="ABO94212">
        <property type="protein sequence ID" value="ABO94212"/>
        <property type="gene ID" value="OSTLU_4812"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_4812"/>
    <dbReference type="eggNOG" id="KOG2421">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013007_1_0_1"/>
    <dbReference type="OMA" id="HANGRMI"/>
    <dbReference type="OrthoDB" id="1058301at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051578">
        <property type="entry name" value="GDPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="5">
        <location>
            <begin position="15"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABO94212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="314" mass="33392" checksum="36300D38C66FDCBB" modified="2007-05-15" version="1" fragment="single">PGLFEPAGCAVIGHRGLQANRASGAGIRENTLASFNAASAGGAEWCEFDVQVTADGVPVAWHDDVVIIPSNALGVEKTVPLTTDDEDDEDDDDYDEDDNKVTFYRVFGGDLEPQPWVMEVEDEIPTLAQILGNTPKELGFNIELKFDEENSCETRRLVAELRAILAVCMAQPSRRIVFSSFDPDAALLMRAIQGSYPVMILTDAEPHHVDPRRRSVAAAMEVALEGGLCGVVSNVKAIISRPSDATDVRDSGLLLATYGEGNDDVAASSTQVELGVFGIITDAVPAVAKKFNATTVNPGNLAPALAPLVSPSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRL4</accession>
    <name>A4RRL4_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">OSTLU_39738</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CCE9901</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415923.1">
        <property type="nucleotide sequence ID" value="XM_001415886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRL4"/>
    <dbReference type="STRING" id="436017.A4RRL4"/>
    <dbReference type="GeneID" id="4999480"/>
    <dbReference type="Gramene" id="ABO94215">
        <property type="protein sequence ID" value="ABO94215"/>
        <property type="gene ID" value="OSTLU_39738"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_39738"/>
    <dbReference type="eggNOG" id="KOG1147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_1_2_1"/>
    <dbReference type="OMA" id="CPVVDSH"/>
    <dbReference type="OrthoDB" id="10250478at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10289">
        <property type="entry name" value="GST_C_AaRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000070">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000004">
        <property type="entry name" value="Glutamyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="13">
        <location>
            <begin position="71"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABO94215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="749" mass="83233" checksum="8B7861FBFF0FFB03" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRU7</accession>
    <name>A4RRU7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pentatrichopeptide repeat (PPR) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PPR7</name>
        <name evidence="5" type="ORF">OSTLU_29142</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO94256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415964.1">
        <property type="nucleotide sequence ID" value="XM_001415927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRU7"/>
    <dbReference type="STRING" id="436017.A4RRU7"/>
    <dbReference type="GeneID" id="4999912"/>
    <dbReference type="Gramene" id="ABO94256">
        <property type="protein sequence ID" value="ABO94256"/>
        <property type="gene ID" value="OSTLU_29142"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29142"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_433067_0_0_1"/>
    <dbReference type="OMA" id="SCTINMN"/>
    <dbReference type="OrthoDB" id="42736at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051114">
        <property type="entry name" value="Mito_RNA_Proc_CCM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934:SF6">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN PET309, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="143"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="274"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="312"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="387"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="422"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABO94256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="632" mass="69347" checksum="FB34C2E94ECCD2CB" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A4RRV2</accession>
    <name>A4RRV2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">OSTLU_29146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415632.1">
        <property type="nucleotide sequence ID" value="XM_001415595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RRV2"/>
    <dbReference type="GeneID" id="4999830"/>
    <dbReference type="Gramene" id="ABO93924">
        <property type="protein sequence ID" value="ABO93924"/>
        <property type="gene ID" value="OSTLU_29146"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29146"/>
    <dbReference type="eggNOG" id="ENOG502SDI7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058904_0_0_1"/>
    <dbReference type="OMA" id="RACKWIT"/>
    <dbReference type="OrthoDB" id="498740at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO93924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="281" mass="31359" checksum="D920678067028D9A" modified="2007-05-15" version="1">MATNVECHAEDAFIRGLTKDAVSWYLEDAYGDSLGRDGARARFVGRELGGWYLQQLIKLGAATSTAIAHPPLSRKFLLWDLDMIPLRPLTLFKGEIPVRQIGGNVIKSYEAAYETLTGDRLKYAKDGTSYVTHQMVVDASIMEEMLDAFARKADRTDELATTSDELPRWATAVLQSLNRKDLTLGFSEYATYASYVVDNHPSEVSVESRKKWARASGGKLGISFQRWINHDGLCCPGPGVLGLMKSRRFDYVGHEIGHVESCRYDSPEHEFSYGLPITVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4RS25</accession>
    <name>A4RS25_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PsbP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_29220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000581">
        <property type="protein sequence ID" value="ABO93959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001415667.1">
        <property type="nucleotide sequence ID" value="XM_001415630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RS25"/>
    <dbReference type="STRING" id="436017.A4RS25"/>
    <dbReference type="GeneID" id="4999985"/>
    <dbReference type="Gramene" id="ABO93959">
        <property type="protein sequence ID" value="ABO93959"/>
        <property type="gene ID" value="OSTLU_29220"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_29220"/>
    <dbReference type="eggNOG" id="ENOG502QT1A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1417289_0_0_1"/>
    <dbReference type="OMA" id="FRIGRAK"/>
    <dbReference type="OrthoDB" id="2013293at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO93959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="192" mass="20806" checksum="EAD518746635B3A6" modified="2007-05-15" version="1">MGEPEAARAEAALTTYEDDKLKFKVQYPSDWTTSTGETPASEEILGGGARDLFTISPPGANARDVNVTIVATPAGADFTKMGSLGDAYGFGYGLVVPLNKPRAKKGQEDRIQFAELIDSVGKGDYYKVEYKFAKPSTGINSIFFVLAGLGYDGRVSHLYTATAQYPRAEEDKWRAQVEAIIDSVVYPPTIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSE2</accession>
    <name>A4RSE2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidyl-prolyl cis-trans isomerase, FKBP-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FBP72</name>
        <name evidence="1" type="ORF">OSTLU_14365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416264.1">
        <property type="nucleotide sequence ID" value="XM_001416227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSE2"/>
    <dbReference type="STRING" id="436017.A4RSE2"/>
    <dbReference type="GeneID" id="5000151"/>
    <dbReference type="Gramene" id="ABO94557">
        <property type="protein sequence ID" value="ABO94557"/>
        <property type="gene ID" value="OSTLU_14365"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_14365"/>
    <dbReference type="eggNOG" id="KOG0543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_427229_0_0_1"/>
    <dbReference type="OMA" id="WRARCDW"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF8">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABO94557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="637" mass="70631" checksum="3DBE2B26AD772861" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSJ2</accession>
    <name>A4RSJ2_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">OSTLU_30239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416238.1">
        <property type="nucleotide sequence ID" value="XM_001416201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSJ2"/>
    <dbReference type="GeneID" id="5000324"/>
    <dbReference type="Gramene" id="ABO94531">
        <property type="protein sequence ID" value="ABO94531"/>
        <property type="gene ID" value="OSTLU_30239"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_30239"/>
    <dbReference type="HOGENOM" id="CLU_3090649_0_0_1"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="52" mass="6079" checksum="5046F865CDA986AA" modified="2007-05-15" version="1">MTSHEPWIYTYFTPFSSKSLILQHLREVVPNANLLAFACLAFVFIDHLLVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSR8</accession>
    <name>A4RSR8_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidic acid Phosphatase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Pap2</name>
        <name evidence="2" type="ORF">OSTLU_119604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CCE9901</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416200.1">
        <property type="nucleotide sequence ID" value="XM_001416163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSR8"/>
    <dbReference type="STRING" id="436017.A4RSR8"/>
    <dbReference type="GeneID" id="5000292"/>
    <dbReference type="Gramene" id="ABO94493">
        <property type="protein sequence ID" value="ABO94493"/>
        <property type="gene ID" value="OSTLU_119604"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119604"/>
    <dbReference type="eggNOG" id="ENOG502QPKC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1013341_0_0_1"/>
    <dbReference type="OrthoDB" id="1716650at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003832">
        <property type="entry name" value="DUF212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446">
        <property type="entry name" value="ACID PHOSPHATASE/VANADIUM-DEPENDENT HALOPEROXIDASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446:SF29">
        <property type="entry name" value="ACID PHOSPHATASE_VANADIUM-DEPENDENT HALOPEROXIDASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02681">
        <property type="entry name" value="DUF212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABO94493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="275" mass="29718" checksum="A72D7744F0ADE9A4" modified="2007-05-15" version="1">MSSSMVVPSRGLRASSFRIQSDRSTIKHGAAFITRRSTNTLAPSLTFLYTNAGSPVRGSVCSTTSETMQSTTPETIEELQLCQEELYCVPQGSSRIIFSAQDPFSDRVATRANALSAVPVGVSFSTAFSDLTGNHAFMCAFLSWLVAQVAKIFTAYYREGRWDYRVMFDSGGMPSSHTALVVGLTTSIAHLHGLGSVHFPMSLAFTLIVMYDAAGVRRHAGKQAEVLNKILADTFHGSPLSNTKLKEVLGHSPLQVVCGAILGVLVASFYMLKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>A4RSZ7</accession>
    <name>A4RSZ7_OSTLU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RWP-RK domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Rwp1</name>
        <name evidence="8" type="ORF">OSTLU_119524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CCE9901</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative transcription factor.</text>
    </comment>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416406.1">
        <property type="nucleotide sequence ID" value="XM_001416369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RSZ7"/>
    <dbReference type="STRING" id="436017.A4RSZ7"/>
    <dbReference type="GeneID" id="5000529"/>
    <dbReference type="Gramene" id="ABO94699">
        <property type="protein sequence ID" value="ABO94699"/>
        <property type="gene ID" value="OSTLU_119524"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119524"/>
    <dbReference type="eggNOG" id="ENOG502QSPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071153_2_0_1"/>
    <dbReference type="OMA" id="PCYKIPQ"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044607">
        <property type="entry name" value="RKD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373">
        <property type="entry name" value="PROTEIN RKD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373:SF2">
        <property type="entry name" value="RWP-RK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="7">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABO94699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="121" mass="14052" checksum="0E14BEC6715FCFAE" modified="2007-05-15" version="1">MTSKQQLISMYAVLKIEDAAKELGMGTTALKKRCRQYGIHRWPHRQLKSLDNLIDALEKLTDDSTGDSTDASCIETAIMQLKYHRQRIAKDPCYKIPQSVFRLRQAQFKDKHRRTKEVNCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4RT10</accession>
    <name>A4RT10_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Pph1</name>
        <name evidence="11" type="ORF">OSTLU_119508</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name="Putnam N."/>
                <person name="Dupont C."/>
                <person name="Jorgensen R."/>
                <person name="Derelle E."/>
                <person name="Rombauts S."/>
                <person name="Zhou K."/>
                <person name="Otillar R."/>
                <person name="Merchant S.S."/>
                <person name="Podell S."/>
                <person name="Gaasterland T."/>
                <person name="Napoli C."/>
                <person name="Gendler K."/>
                <person name="Manuell A."/>
                <person name="Tai V."/>
                <person name="Vallon O."/>
                <person name="Piganeau G."/>
                <person name="Jancek S."/>
                <person name="Heijde M."/>
                <person name="Jabbari K."/>
                <person name="Bowler C."/>
                <person name="Lohr M."/>
                <person name="Robbens S."/>
                <person name="Werner G."/>
                <person name="Dubchak I."/>
                <person name="Pazour G.J."/>
                <person name="Ren Q."/>
                <person name="Paulsen I."/>
                <person name="Delwiche C."/>
                <person name="Schmutz J."/>
                <person name="Rokhsar D."/>
                <person name="Van de Peer Y."/>
                <person name="Moreau H."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="17460045"/>
            <dbReference type="DOI" id="10.1073/pnas.0611046104"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CCE9901</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CP000582">
        <property type="protein sequence ID" value="ABO94690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_001416397.1">
        <property type="nucleotide sequence ID" value="XM_001416360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RT10"/>
    <dbReference type="STRING" id="436017.A4RT10"/>
    <dbReference type="GeneID" id="5000225"/>
    <dbReference type="Gramene" id="ABO94690">
        <property type="protein sequence ID" value="ABO94690"/>
        <property type="gene ID" value="OSTLU_119508"/>
    </dbReference>
    <dbReference type="KEGG" id="olu:OSTLU_119508"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013173_20_0_1"/>
    <dbReference type="OMA" id="PECWSGS"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000001568">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080005">
        <property type="term" value="P:photosystem stoichiometry adjustment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF589">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="10">
        <location>
            <begin position="93"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABO94690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001568"/>
        </source>
    </evidence>
    <sequence length="388" mass="42151" checksum="6C46D10A6FEEE81E" modified="2007-05-15" version="1">MKVAPLQQVATVSSPKLVSRHFRHKRRTVQSGSRFPLSDLNGLLTGGELAGLVATCLAAVIVSNASRATTSSVDSLEQVRKPAAKVRRPVDLDWGACSDIGPRDYMEDAYQVVKGPDHFFAAVYDGHGGCGSSTYLRSNFYKFVSAMLGKNRKLLSDETTTDDEMNTIFEKSMSEVFMAADSALIDYIATLGDPECWSGSTATVCVVNSSLLMCANVGDSRAVLCRSGKPVDISADHRPTTSSSCGRCEIKRINQAGGWISQSRVCGILAVTRAFGDYEFKGGRYELLEELKDSSDILAMKASMEGPPVISLPHCFTIPRSTEDEFIILASDGLWDTMNSAQAVTFVRSELKKDPSKSMQDIADALIARALRCRTQDNVVCIVVKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RTF5</accession>
    <name>A4RTF5_OSTLU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">OSTLU_29894</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ostreococcus lucimarinus (strain CCE9901)</name>
        <dbReference type="NCBI Taxonomy" id="436017"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Bathycoccaceae</taxon>
            <taxon>Ostreococcus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Proc. Natl. Acad. Sci. U.S.A." volume="104" first="7705" last="7710">
            <title>The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.</title>
            <authorList>
                <person name="Palenik B."/>
                <person name="Grimwood J."/>
                <person name="Aerts A."/>
                <person name="Rouze P."/>
                <person name="Salamov A."/>
                <person name=